
Thibério de Souza Castelo, Thiago Rodrigues Frota, Alexandre Rodrigues Silva,
The goat semen cryopreservation is an important reproductive biotechnique that promotes the conservation of male germplasm indefinitely. This technique, associated to the artificial insemination, represents an efficient mechanism for promotion and diffusion of the high quality genetic material. Semen cryopreservation provides an economy for the producer when reducing the costs with feeding and transport of the stud males, as well as the risks of transmission of sexually transmissible diseases. The ...
Tópico(s): Reproductive Biology and Fertility
2008 - University of Veterinary and Pharmaceutical Sciences, Brno | Acta Veterinaria Brno

Ana C.A. Frota, Alexandre Nakao Odashiro, Patrícia M. R. Pereira, Bruno F. Fernandes, K.D. Godeiro, J.P. Souza Filho, Miguel N. Burnier,
We report a case of choroidal melanoma metastatic to the liver diagnosed by fine-needle aspiration. The biopsy sample was immunostained for COX-2 and c-kit.Accurate diagnosis and identification of potential therapeutic targets are important for subsequent therapy and can be achieved by radiologically guided fine-needle aspiration biopsy.
Tópico(s): Peptidase Inhibition and Analysis
2007 - Elsevier BV | Canadian Journal of Ophthalmology

Alexandre Magno Frota Monteiro, Raquel Luiza Santos, Nathália Kimura, Maria Alice Tourinho Baptista, Márcia Cristina Nascimento Dourado,
Abstract Introduction Caregivers of people with Alzheimer disease (PwAD) report significant stress, burden and depression compared to caregivers of people with other dementias, especially when neuropsychiatric symptoms are prominent. Adequate coping strategies can modify the impact of stressful situations and increase the caregivers’ quality of life. Objective To systematically review the different coping strategies used by caregivers of PwAD to manage neuropsychiatric symptoms. Method We carried ...
Tópico(s): Mental Health Treatment and Access
2018 - Associação de Psiquiatria do Rio Grande do Sul | Trends in Psychiatry and Psychotherapy

Márcia Cristina Nascimento Dourado, Tatiana Belfort, Alexandre Magno Frota Monteiro, Aline Tavares de Lucena, Isabel Barbeito Lacerda, Julia Gaigher, Maria Alice Tourinho Baptista, Michelle Brandt, Nathália Ramos Kimura, Natalie de Souza, Paula Gasparini, Rogéria Rangel, Valeska Marinho,
The COVID-19 pandemic has raised significant concerns about the management and care for people with dementia and their caregivers. In this context, this work will discuss how social isolation or social distancing caused by the pandemic may impact the clinical management of people with dementia, caregivers' health, and dementia research. The pandemic disrupts all forms of social interaction and may increase the behavioral impairment of people with dementia. Regarding pharmacological treatment, telemedicine ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2020 - Associação Neurologia Cognitiva e do Comportamento | Dementia & Neuropsychologia

Lívia Érika Carlos Marques, Cristiane Cunha Frota, Josiane da Silva Quetz, Alexandre Havt, Rosa Maria Salane Mota, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Carl Kendall, Lígia Regina Franco Sansigolo Kerr,
Mycobacterium leprae bacilli are mainly transmitted by the dissemination of nasal aerosols from multibacillary (MB) patients to susceptible individuals through inhalation. The upper respiratory tract represents the main entry and exit routes of M. leprae. Therefore, this study aimed to evaluate the sensitivity and specificity of real-time quantitative polymerase chain reaction (qPCR) in detecting M. leprae in nasal secretion (NS) and skin biopsy (SB) samples from MB and paucibacillary (PB) cases. Fifty- ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2017 - Taylor & Francis | Pathogens and Global Health

K.D. Godeiro, Ana de Arantes Frota, E. Antecka, Alexandre Nakao Odashiro, S. Maloney, Bruno F. Fernandes, Miguel N. Burnier,
Choroidal neovascular membrane (CNVM) is one of the leading causes of severe visual loss and is often associated with age-related macular degeneration (AMD). Various modalities of treatment, including photocoagulation and surgery, are being considered as options, but with limited success. Prostate-specific membrane antigen (PSMA) is a type II membrane glycoprotein expressed in benign and malignant prostatic tissues, in some non-prostatic tissues, and in the endothelium of tumor-associated neovasculature ...
Tópico(s): Glaucoma and retinal disorders
2006 - Medknow | Journal of Carcinogenesis

Clotilde Druck Garcia, João Carlos Goldani, Ajácio Brandão, Sérgio R. Haussen, Jorge Neumann, Eduardo Mainieri Chem, Fernando Lucchese, José Dario Frota Filho, Alexandre S. Marcon, Santo Pascoal Vitola, V. Bittencourt, A.P. Barboza, Roberto Chem, José de Jesus Peixoto Camargo, Ítalo Mundialino Marcon, ANTONIO NOCCI KALIL, Lúcia Elbern, Elizabeth de Carvalho Castro, João Rafael Victor Schmitt, Valter Duro Garcı́a,
Objetivo: Educar precocemente futuros profissionais de saúde, alunos de Medicina, Nutrição e Biomedicina, visando aumentar seu conhecimento sobre doação e transplantes e qualificá-los para divulgar informações, produzindo uma resposta positiva, reforçando seu compromisso com esse processo, para aumentar o número insuficiente de doadores. Métodos: A fim de fornecer as informações necessárias sobre o processo de doação-transplante, a Universidade Federal de Ciências da Saúde de Porto Alegre, associada ...
Tópico(s): Palliative Care and End-of-Life Issues
2009 - | Brazilian Journal of Transplantation

Thaís Sousa Mendes, Edmundo Frota de Almeida Sobrinho, Alexandre Antônio Marques Rosa, Laiza Medeiros dos Anjos, Genilma Matos da Costa, Givago da Silva Souza, Bruno Gomès, Cézar Akiyoshi Saito, Manoel da Silva Filho, Luiz Carlos L. Silveira,
Tópico(s): Retinal and Optic Conditions
2009 - Springer Science+Business Media | Documenta Ophthalmologica

David Darnis Bezerra da Silva, Clódis Maria Tavares, Nataly Mayara Cavalcante Gomes, Aline Costa Cardoso, Ricardo Alexandre Arcêncio, Paula Sacha Frota Nogueira,
Abstract Objective: to describe the epidemiological profile of elderly persons with leprosy in the state of Alagoas. Method: a descriptive epidemiological study of leprosy cases among the elderly reported to the Disease Notification Information System between 2005 and 2015 was carried out. Results: a total of 896 cases were identified, with a predominance of 60-69 years old (60.5%), who were male (50.4%), had no schooling (34.8%), no source of income (54.1%), multibacillary forms of the disease (67.9%), ...
Tópico(s): Health, Nursing, Elderly Care
2018 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Revista Brasileira de Geriatria e Gerontologia

... Ministro da Educacao reuniu-se com o ator Alexandre Frota e representantes do Revoltados On Line e Escola ...
Tópico(s): Gender, Sexuality, and Education
2016 - | Ponto Urbe

Mauro Macêdo de Oliveira, Hélcio Silva dos Santos, Henrique Douglas Melo Coutinho, Paulo Nogueira Bandeira, Priscila T. da Silva, Thiago Sampaio de Freitas, Janaína Esmeraldo Rocha, Jayze da Cunha Xavier, Fábia F. Campina, Cristina Rodrigues dos Santos Barbosa, José Bezerra de Araújo Neto, Raimundo Luíz Silva Pereira, Maria Milene Costa da Silva, Débora Feitosa Muniz, Alexandre Magno Rodrigues Teixeira, Vanessa Moreira Frota, Tigressa Helena Soares Rodrigues, Ana M. Amado, M. Paula M. Marques, Luís A. E. Batista de Carvalho, C.E.S. Nogueira,
Curcumin, along with its derivatives, form a large class of natural and synthetic compounds with notable biological activity. However, their highly reactive β-diketone moiety renders this type of compounds unstable at pH above 6.5. The substitution of this group for a mono-carbonyl solves this problem, while improving antibacterial and anti-inflammatory activities. A thiophene curcuminoid, (1E,4E)-1,5-Di(thiophen-2-yl)penta-1,4-dien-3-one (DB Thiophene), has been synthesised and its molecular and ...
Tópico(s): Synthesis and biological activity
2020 - Elsevier BV | Journal of Molecular Structure

Natália de Souza Xavier Costa, Gabriel Ribeiro Júnior, Adair Aparecida dos Santos Alemany, Luciano Belotti, Alexandre Santos Schalch, Marcela Frota Cavalcante, Susan Pereira Ribeiro, Mariana Matera Veras, Esper G. Kallás, Paulo Hilário Nascimento Saldiva, Marisa Dolhnikoff, Luiz Fernando Ferraz da Silva,
Abstract Evidence regarding the impact of air pollution on acute respiratory distress syndrome (ARDS) is limited, and most studies focus on ARDS onset. Our study aimed to evaluate whether exposure to fine particulate matter interferes with lung recovery and remodeling in a murine model of acute lung injury. Forty-eight mice received nebulized LPS or the vehicle (controls). Blood, BALF, lungs and spleen were collected after 5 weeks of exposure to either PM 2.5 (PM and LPS + PM group) or filtered air (control ...
Tópico(s): Infection Control and Ventilation
2020 - Nature Portfolio | Scientific Reports

Danilo Teixeira Noritomi, Roberto de Cleva, Idal Beer, Alexandre Garcia Dalbem, Alexandre Braga Libório, Norberto Anízio Ferreira Frota, Joaquim Gama‐Rodrigues,
The true incidence of subarachnoid hemorrhage (SAH) as a cause of cardiopulmonary arrest (CPA) is difficult to determine, but it can be relatively common in some populations, especially in the young subgroups.1Shapiro S. Management of subarachnoid hemorrhage patients who presented with respiratory arrest resuscitated with bystander CPR.Stroke. 1996; 27: 1780-1782Crossref PubMed Scopus (27) Google Scholar, 2Bonita R. Thomson S. Subarachnoid hemorrhage: epidemiology, diagnosis, management, and outcome. ...
Tópico(s): Cardiac Arrest and Resuscitation
2006 - Elsevier BV | Resuscitation

Moisés Rocha dos Santos, Eduardo Dorneles Ferreira de Souza, Mateus Barros Frota de Carvalho, Alexandre César Muniz de Oliveira, Areolino de Almeida Neto, Marco Rocha Curado, Paulo R. A. Ribeiro,
Machine Learning (ML) has been widely and successfully employed in different fields to estimate information from datasets. However, the necessary time to learn a motor task or to rehabilitate is mainly determined by the professional experience of medical doctor, physiotherapist and so on. Thus, this work introduces a software to measure the performance of subjects on a experiment performing a tracing task, which requires motor learning, and uses ML algorithms on the dataset acquired during this experiment. ...
Tópico(s): Motor Control and Adaptation
2019 - Springer Science+Business Media | Lecture notes in computer science

Eduardo Alexandre Rancan, Eloísa Ianes Frota, Tábata Marina Nóbrega de Freitas, Maria Cecília Jordani, Paulo Roberto Barbosa Évora, Orlando de Castro e Silva,
Purpose To evaluate the effects of treatment with Indigo Carmine (IC) on rat livers subjected to ischemia-reperfusion injury. Methods The animals were subdivided into 4 groups: 1.SHAM group(SH) - saline; 2.SHAM group with IC-2mg/Kg(SHIC); 3.IR group - rats submitted to ischemia and reperfusion with saline(IR); 4.IR group with IC-2mg/Kg(IRIC). The IR protocol consists of liver exposure and administration of drug or saline intravenously, followed by 60 minutes of ischemia and 15 of reperfusion. Liver samples ...
Tópico(s): Neuroscience and Neuropharmacology Research
2020 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Alexandre Gnaho, Vinh Nguyen, Thierry Villevielle, Melina Frota, Emmanuel Marret, Marc Gentili,
To assess the accuracy of the ultrasound (US) to predict the depth to reach lumbar intrathecal and epidural spaces in order to decrease the number of puncture attempts. Thirty-one patients (25 males and 6 females), ASA I or II participated in this study. The transversal ultrasound image of the lumbar spine was obtained at the level of the L3–L4 space. An anesthesiologist without prior information performed the spinal anesthesia through the predicted target area. The distance between the skin and the ...
Tópico(s): Intraoperative Neuromonitoring and Anesthetic Effects
2012 - Elsevier BV | Brazilian Journal of Anesthesiology

Alexandre Ribas Semeler, Adílson Luiz Pinto, Helen Beatriz Frota Rozados,
Currently, data are stored in an always-on condition, and can be globally accessed at any point, by any user. Data librarianship has its origins in the social sciences. In particular, the creation of data services and data archives, in the United Kingdom (Data Archives Services) and in the United States and Canada (Data Library Services), is a key factor for the emergence of data librarianship. The focus of data librarianship nowadays is on the creation of new library services. Data librarians are ...
Tópico(s): Privacy-Preserving Technologies in Data
2017 - SAGE Publishing | Journal of Librarianship and Information Science

Danielle L. da Silva, Camila Mendes de Lima, Vanessa Caroline Randi Magalhães, Ludmila Matos Baltazar, Nalu T. A. Peres, Rachel Basques Caligiorne, Alexandre Sampaio Moura, Tatiani Fereguetti, José Martins, Lívia Frota Rabelo, Jônatas Santos Abrahão, Anders Lyon, Susana Johann, Daniel Assis Santos,
SARS-CoV-2 predisposes patients to secondary infections; however, a better understanding of the impact of coinfections on the outcome of hospitalized COVID-19 patients is still necessary.To analyse death risk due to coinfections in COVID-19 patients.The odds of death of 212 severely ill COVID-19 patients were evaluated, with detailed focus on the risks for each pathogen, site of infection, comorbidities and length of hospitalization.The mortality rate was 50.47%. Fungal and/or bacterial isolation ...
Tópico(s): Antifungal resistance and susceptibility
2021 - Elsevier BV | Journal of Hospital Infection

Sérgio B. Legoas, Alexandre A. Araújo, B. Laks, A. B. Klautau, S. Frota-Pessôa,
We report results for the surface band structures of molybdenum and tungsten (001) surfaces by employing the surface version of the first-principles, self-consistent real-space linear muffin-tin orbital method in the atomic sphere approximation. The surface state dispersions as well as the spectral density of states were obtained employing the transfer matrix scheme. The resulting surface band structures are compared with recent experimental measurements at temperatures above the transition temperature, ...
Tópico(s): Physics of Superconductivity and Magnetism
2000 - American Physical Society | Physical review. B, Condensed matter

Joabi Nascimento, José Diego Brito-Sousa, Anne Cristine Gomes de Almeida, Marly Marques de Melo, Mônica Regina Farias Costa, Laila R. A. Barbosa, Reinaldo Nery Ramos, Alexandre Vilhena Silva-Neto, Patrícia Carvalho da Silva Balieiro, Erick Frota Gomes Figueiredo, Emanuelle Lira Silva, Djane Clarys Baía-da-Silva, Quique Bassat, Gustavo Adolfo Sierra Romero, Gisely Cardoso de Melo, Vanderson de Souza Sampaio, Marcus Lacerda, Wuelton Marcelo Monteiro,
Difficulties associated with the assessment of glucose-6-phosphate dehydrogenase deficiency (G6PDd), particularly in remote areas, hinders the safe use of 8-aminoquinolines such as primaquine (PQ) and tafenoquine against Plasmodium vivax malaria due to the risk of haemolysis.This cross-sectional study was conducted in 41 malaria-endemic municipalities of six states in the Brazilian Amazon, between 2014 and 2018. Male individuals were screened for G6PDd using the qualitative Fluorescent Spot Test using ...
Tópico(s): Methemoglobinemia and Tumor Lysis Syndrome
2022 - Elsevier BV | The Lancet Regional Health - Americas

Naila Cristina Soler-Camargo, Taiana Tainá Silva‐Pereira, Cristina Kraemer Zimpel, Maurício Frota Camacho, André Zelanis, Alexandre Hild Aono, José Salvatore Leister Patané, Andrea Pires dos Santos, Ana M. S. Guimarães,
Whole-genome sequence analyses have significantly contributed to the understanding of virulence and evolution of the Mycobacterium tuberculosis complex (MTBC), the causative pathogens of tuberculosis. Most MTBC evolutionary studies are focused on single nucleotide polymorphisms and deletions, but rare studies have evaluated gene content, whereas none has comprehensively evaluated pseudogenes. Accordingly, we describe an extensive study focused on quantifying and predicting possible functions of MTBC ...
Tópico(s): Bacteriophages and microbial interactions
2022 - Microbiology Society | Microbial Genomics

Clarissa Frota Macatrão Costa, Valério Monteiro‐Neto, Bruno Rafael de Carvalho Santos, Bruno Rafael Rabelo Costa, Alexandre Santana Azevedo, Josilene Lima Serra, Hermínio Benitez Rabello Mendes, Adenilde Ribeiro Nascimento, Mariana Bonfim, Oliver Kuppinger,
The Port Complex of Maranhão (PCM) is the second largest port complex in Brazil, receiving ships with large volumes of ballast water. To evaluate the microbiological quality of its waters, physicochemical parameters (pH and salinity), the number of coliforms (thermotolerants and totals), and the presence of enterobacterias and diarrheagenic Escherichia coli strains were analyzed. In order to identify the presence of E. coli virulence genes target regions of the stx, elt, est, aggR, CVD432, ipaH and ...
Tópico(s): Fecal contamination and water quality
2014 - Springer Nature | Brazilian Journal of Microbiology
Rafaella Pessoa Moreira, Clara Beatriz Costa da Silva, Tainara Chagas de Sousa, Flávia Lavinnya Betsaida Félix Leitão, Huana Carolina Cândido Morais, Andressa Suelly Saturtino de Oliveira, Gonzalo Duarte Clíments, María Begoña Sánchez Gómez, Tahissa Frota Cavalcante, Alexandre Cunha Costa,
In the face of escalating global aridification, this study examines the complex relationship between climate variability, air pollution, natural disasters, and the prevalence of cardiovascular disease (CVD) and diabetes mellitus (DM) in arid regions.
Tópico(s): Spaceflight effects on biology
2024 - Springer Science+Business Media | Public health reviews

André Filipe Junqueira dos Santos, Carolina Bisinoto Borges, Lídia Kelsin Fung, Mayra Zanetti, Pedro Kallas Curiati, Vanessa Meirelles Pereira Danzini, Euro de Barros Couto Júnior, Paulo Sérgio Panse Silveira, Luiz Eugênio Garcez Leme,
... Madisson, Marisa Accioly Rodrigues da Costa Domingues, Marcos Alexandre Frota, Marta Nagai Coelho, Mayra Jacuviske Venegas, Maysa Seabra ...
Tópico(s): Retirement, Disability, and Employment
2011 - Wiley | Journal of the American Geriatrics Society

Márcia Perencin Tondato, Lucas Lopes Fraga, Pietro Giuliboni Nemr Coelho,
... na pandemia realizadas nas postagens do deputado federal Alexandre Frota no Instagram, refletindo sobre suas estratégias performáticas que ...
Tópico(s): Cultural, Media, and Literary Studies
2022 - UNIVERSIDADE CATÓLICA DE BRASÍLIA | Esferas

Vitor Pestana Ostrensky, Alexandre Alves Porsse, Leonardo Matsuno da Frota,
Studies in regional science show the influence of public transport on gentrification. However, the vast majority of published works deal with cases in developed countries and do not account for selection bias or endogeneity. This work uses a difference-in-differences model, combined with a propensity score matching, to analyze the effects of new metro stations between 2000 and 2010 in São Paulo, Brazil. The analysis relies on outcome variables typically used in the gentrification literature. The ...
Tópico(s): Transportation Planning and Optimization
2022 - Elsevier BV | Regional Science Policy & Practice

José Diego Brito-Sousa, Felipe Murta, Sheila Vítor-Silva, Vanderson de Souza Sampaio, Maxwell O. Mendes, Marcelo Augusto Mota Brito, Talita S. B. Batista, Alícia Cacau Santos, Leonardo Lincoln Gomes Marques, Laila R. A. Barbosa, Marly Marques de Melo, Djane Clarys Baía-da-Silva, Alexandre Vilhena Silva-Neto, Thaliê Cavalcante Santos, Brenda K. A. Souza, Erick Frota Gomes Figueiredo, Emanuelle L. Silva, Sheila Rodovalho, Theresa Helissa Nakagawa, Ana Ruth Lima Arcanjo, André M. Siqueira, Gisely Cardoso de Melo, Judith Recht, Gonzalo J. Domingo, Quique Bassat, Germana Bancone, Wuelton Marcelo Monteiro, Marcus Lacerda,
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency greatly hinders Plasmodium vivax malaria radical cure and further elimination due to 8-aminoquinolines-associated hemolysis. Although the deleterious health effects of primaquine in G6PD deficient individuals have been known for over 50 years, G6PD testing is not routinely performed before primaquine treatment in most P . vivax endemic areas. Method/Principal findings The qualitative CareStart G6PD screening test was implemented in 12 malaria ...
Tópico(s): Methemoglobinemia and Tumor Lysis Syndrome
2021 - Public Library of Science | PLoS neglected tropical diseases

Elias da Silva Santos, Karina Alexandre Barros Nogueira, Luiziana Cavalcante Costa Fernandes, Jéssica Roberta Pereira Martins, Alice Vitoria Frota Reis, José de Brito Vieira Neto, Ivanildo José da Silva, Cláudia Pessoa, Raquel Petrilli, Josimar O. Eloy,
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family and is present in the epithelial cell membrane. Its endogenous activation occurs through the binding of different endogenous ligands, including the epidermal growth factor (EGF), leading to signaling cascades able to maintain normal cellular functions. Although involved in the development and maintenance of tissues in normal conditions, when EGFR is overexpressed, it stimulates the growth and progression of ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2020 - Elsevier BV | International Journal of Pharmaceutics

Bruno Rodrigues Arruda, Maria Gabriela Araújo Mendes, Paulo George Cavalcante de Freitas, Alice Vitoria Frota Reis, Thayane Soares Lima, Luiziana Cavalcante Costa Fernandes Crisóstomo, Karina Alexandre Barros Nogueira, Cláudia Pessoa, Raquel Petrilli, Josimar O. Eloy,
Paclitaxel (PTX), Docetaxel (DTX) and Cabazitaxel (CTX) are taxanes: substances that belong to a class of diterpenes derived from plants of the Taxus genus (yew). Taxanes are currently used in clinical practice for the treatment of various types of cancer, including breast, ovarian, lung, and prostate, among others. Despite their wide applications, taxanes have some disadvantages that can hinder their use as a chemotheraputic, including low solubility, high toxicity and induction of multidrug resistance ( ...
Tópico(s): Advanced Drug Delivery Systems
2022 - Elsevier BV | Journal of Drug Delivery Science and Technology

Vanessa da Frota Santos, Ana Karoline Bastos Costa, Ivana Cristina Vieira de Lima, Herta de Oliveira Alexandre, Elucir Gir, Marli Teresinha Gimeniz Galvão,
Resumo O objetivo deste artigo é avaliar a eficácia do uso do telefone para adesão de pessoas com HIV/AIDS à terapia antirretroviral. Realizou-se uma revisão sistemática, nas bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs/Bireme), Scopus, Medical Literature Analysis and Retrieval System Online (Medline/PubMed), Web of Science; e nas bibliotecas Scientific Eletronic Library Online (SciELO) e Cochrane, com uso dos seguintes descritores: “HIV”, “Cell Phones”, “Acquired ...
Tópico(s): Science and Education Research
2019 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva