
Bianca de Lemos Zingano, Ricardo Guarnieri, Alexandre Paim Díaz, Marcelo Libório Schwarzbold, Peter Wolf, Kátia Lin, Roger Walz,
Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is the most prevalent type of surgically remediable epilepsy and highly associated with psychiatric comorbidities. This study aimed to evaluate Hospital anxiety and depression scale-anxiety subscale (HADS-A) and The State-Trait Anxiety Inventory – Trait subscale (STAI-T) accuracy for detection of anxiety disorders in patients with drug-resistant MTLE-HS. One hundred three consecutive patients with drug-resistant MTLE-HS were enrolled. ...
Tópico(s): EEG and Brain-Computer Interfaces
2018 - Elsevier BV | Journal of Affective Disorders

Bianca de Lemos Zingano, Ricardo Guarnieri, Alexandre Paim Díaz, Marcelo Libório Schwarzbold, Maria Alice Horta Bicalho, Lucia Sukys-Claudino, Hans J. Markowitsch, Peter Wolf, Kátia Lin, Roger Walz,
This study aimed to evaluate the diagnostic accuracy of the Hamilton Rating Scale for Depression (HRSD), the Beck Depression Inventory (BDI), the Hospital Anxiety and Depression Scale (HADS), and the Hospital Anxiety and Depression Scale-Depression subscale (HADS-D) as diagnostic tests for depressive disorder in drug-resistant mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS).One hundred three patients with drug-resistant MTLE-HS were enrolled. All patients underwent a neurological examination, ...
Tópico(s): Neurological disorders and treatments
2015 - Elsevier BV | Epilepsy & Behavior

Jean Costa Nunes, Danielle Brandes Zakon, Lucia Sukys-Claudino, Ricardo Guarnieri, Alexandre Bastos, Luiz Paulo Queiroz, Roger Walz, Kátia Lin,
PurposeTo investigate the frequency and patterns of headache in a well-defined and homogeneous group of mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) patients.MethodsOne hundred consecutive MTLE-HS patients under comprehensive presurgical evaluation were evaluated from May 2009 to April 2010. A standardized questionnaire was applied according to the criteria of the International Headache Society (IHS). Headache diagnosis was based on the second edition of the International Classification ...
Tópico(s): Migraine and Headache Studies
2011 - Elsevier BV | Seizure

Bettina Moritz, Marcelo Libório Schwarzbold, Ricardo Guarnieri, Alexandre Paim Díaz, Ana Lúcia S. Rodrigues, Alcir Luiz Dafré,
Objective Given that the literature data indicates that ascorbic acid may have an anxiolytic effect, we hypothesized that a single oral administration of ascorbic acid could acutely affect emotional states.Methods The effects of acid ascorbic supplementation on anxiety and other emotional states were evaluated by the State-Trait Anxiety Inventory (STAI), and Visual Analogue Mood Scale (VAMS).Immediately before, and 2 hours after receiving a single ascorbic acid dose (1000 mg) or placebo, 142 graduate ...
Tópico(s): Vitamin C and Antioxidants Research
2017 - Nencki Institute of Experimental Biology | Acta Neurobiologiae Experimentalis

Alice Maria Costa Martins, Fabíola Carine Monteiro de Sousa, Paulo Sérgio Ferreira Barbosa, Marcos Hikari Toyama, Daniela O. Toyama, Cleidiana C. Aprígio, Maria Goretti Rodrigues de Queiroz, Mirian C. Guarnieri, Alexandre Havt, Dalgimar B. de Menezes, Manassés Claudino Fonteles, Helena Serra Azul Monteiro,
Acute renal failure is the most common complication in the lethal cases caused by snakebites in Brazil. Among the Brazilian venom snakes, Bothrops erythromelas is responsible for the majority of accidents in Northeastern Brazil. Didelphis marsupialis serum could inhibit myonecrotic, hemorrhagic, edematogenic hyperalgesic and lethal effects of envenomation determined by ophidian bites. In the present study, we evaluated the action of the anti-bothropic factor isolated from D. marsupialis on the renal ...
Tópico(s): Healthcare and Venom Research
2005 - Elsevier BV | Toxicon

César Bündchen Záccaro de Oliveira, W. J. Souza, Carolina F. Sant’Ana, César Costapinto Santana, Cláudio Dariva, Elton Franceschi, Ricardo A. Guarnieri, Montserrat Fortuny, Alexandre F. Santos,
During the crude oil production, stable water-in-oil (W/O) emulsions are generally found along the pipeline between the reservoir and surface facilities. The main objective of this work is discussing about the influence of the salinity (with NaCl at 0, 50, and 100 g·L–1), pH (2, 6, and 10 values), and water content (variations between 8% and 65%) upon the rheological behavior of water-in-crude oil emulsions. Tests including the rotational and oscillatory rheology for assessment of profiles of viscosity, ...
Tópico(s): Hydraulic Fracturing and Reservoir Analysis
2018 - American Chemical Society | Energy & Fuels

Rafael Humberto de Carvalho, Adriana Lourenço Soares, Paulo D. Guarnieri, Alexandre Oba, Elza Iouko Ida, Massami Shimokomaki,
The objective of this study was to determine the incidence of Pale, Soft, Exudative (PSE) meat and to characterize the Dark, Fim, Dry (DFD) meat as well as the Dead on Arrival (DOA) index in a commercial turkey slaughterhouse in southern Brazil during the summer and winter seasons. The journeys (n=64) were over a distance of 36 ± 20 km and took approximately 95 ± 20 min. Color (L*) and pH distribution of turkey breast meat (n=5,352) were evaluated from different farms (n=64) during the 2015-2016 years. The ...
Tópico(s): Identification and Quantification in Food
2018 - Instituto de Tecnologia do Paraná (Tecpar) | Brazilian Archives of Biology and Technology

Bianca Schwab, Heloisa Silveira Daniel, Carine Lutkemeyer, João Arthur Lange Lins Neves, Louise Nassif Zilli, Ricardo Guarnieri, Alexandre Paim Díaz, Ana Maria Maykot Prates Michels,
Health-related quality of life (HRQOL) assessment tools have been broadly used in the medical context. These tools are used to measure the subjective impact of the disease on patients. The objective of this study was to evaluate the variables associated with HRQOL in a Brazilian sample of patients followed up in a tertiary outpatient clinic for depression and anxiety disorders.Cross-sectional study. Independent variables were those included in a sociodemographic questionnaire and the Hospital Anxiety ...
Tópico(s): Health disparities and outcomes
2015 - Associação de Psiquiatria do Rio Grande do Sul | Trends in Psychiatry and Psychotherapy
Menno V. Huisman, Kenneth J. Rothman, Miney Paquette, Christine Teutsch, Hans‐Christoph Diener, Sérgio Dubner, Jonathan L. Halperin, Chang Sheng, Kristina Zint, Amelie Elsaesser, Dorothee B. Bartels, Gregory Y.H. Lip, Dzifa Wosornu Abban, Nasser Abdul, Mark Abelson, Alan Ackermann, Fran Adams, Luthando Adams, Pedro Adragão, Walter Ageno, Rajesh Aggarwal, Sergio Agosti, Javier A. Marin, Francisco Aguilar, Julio Alberto Aguilar Linares, Luis Aguinaga, Zia Ahmad, Paul Ainsworth, Kamal Al Ghalayini, Saad Al Ismail, Abdelfatah Alasfar, Abdul Alawwa, Raed Al-Dallow, Lisa Alderson, Dimitrios Alexopoulos, Abdullah Ali, Malik Ali, Pareed Aliyar, Tammam Al-Joundi, Soufian Al Mahameed, Hossein Almassi, Khalid Almuti, Mohamed Al-Obaidi, Mohamed Al‐Shehri, Ute Altmann, Alvaro Rabelo Alves, Ayham Al-Zoebi, W. Amara, Mathieu Amelot, Nima Amjadi, Fabrizio Ammirati, Nabil Andrawis, Denis Angoulvant, Giorgio Annoni, Gerardo Ansalone, Sorin Alexandru Antonescu, M. Kevin Ariani, Juan Carlos Arias, Sébastien Armero, Rohit Arora, Chander Arora, William Ashcraft, Muhammad Shakil Aslam, Alfredo Astesiano, Philippe Audouin, Charles Augenbraun, Şenay Aydın, Rabih R. Azar, Abul Azim, Shahid Aziz, Luciano Marcelo Backes, Mirza Amir Baig, Suchdeep Bains, Asaad I. Bakbak, Seth Baker, Karim Bakhtiar, Richard Bala, Jonathan Banayan, Stellan Bandh, Shigenobu Bando, Subhash Banerjee, Alan J. Bank, О. Л. Барбараш, Gonzalo Barón‐Esquivias, Craig Barr, Carlos M. Barrera, John R. Barton, Vanja Bašić Kes, Giovanni Baula, Hamid el Bayeh, Nooshin Bazargani, Steffen Behrens, Alan Bell, Juan Benezet‐Mazuecos, Bouziane Benhalima, Philippe Berdagué, Brian J. Berg van den, P.F.M.M. Bergen van, Edvard Berngard, Richard A. Bernstein, Percy Berrospi, Sergio Berti, Vicente Bertoméu, Andrea Berz, Paulo Bettencourt, Robert Betzu, Jan Beyer‐Westendorf, Ravi Bhagwat, Toby Black, Jorge Hugo Blanco Ibaceta, Stephen R. Bloom, Edwin Blumberg, Mario Bo, Valerie Bockisch, Ellen Bøhmer, Maria Grazia Bongiorni, Giuseppe Boriani, Ralph Bosch, D.J. Boswijk, Jochen Bott, E. Bottacchi, Marica Bracic Kalan, Axel Brandes, Bjørn Bratland, Donald Brautigam, Nicolas Breton, Paul J.A.M. Brouwers, Kevin F. Browne, Jordi Bruguera, Myriam Brunehaut, Claude Brunschwig, Hervé Buathier, Aurélie Buhl, John Bullinga, Kenneth Butcher, Jose Walter Cabrera Honorio, Alberto Caccavo, Didier Cadinot, Shanglang Cai, Valéria Calvi, A. John Camm, Rui Candeias, James Capo, Alessandro Capucci, Juliano Novaes Cardoso, Yan Duarte, Brian E. Carlson, Paula Carvalho, Susanna Cary, Rene Casanova, Gavino Casu, Simon Cattan, Claudio Cavallini, Guillaume Cayla, Tae Joon, Kwang Soo, Said Chaaban, Jei Keon Chae, Krishnan Challappa, Sunil Prakash Chand, Harinath Chandrashekar, Mark Chang, Paul Charbel, Ludovic Chartier, Kausik Chatterjee, Aamir Cheema, Shih‐Ann Chen, Pierre Chevallereau, Fu‐Tien Chiang, Francesco Chiarella, Lin Chih-Chan, Yong Keun Cho, Dong Ju Choi, Guy Chouinard, Danny, Hoi Fan Chow, Dimitrios Chrysos, Г. А. Чумакова, Eduardo Chuquiure‐Valenzuela, Tomas Cieza-Lara, Violeta Cindea Nica, Vlad Ciobotaru, David J. Cislowski, Olivier Citerne, Matthias Claus, Anthony Clay, Piers Clifford, Serge Cohen, Andrew Cohen, Furio Colivicchi, Rónán Collins, Steve Compton, Sean P. Connors, Alberto Conti, Gabriel Contreras Buenostro, Gregg Coodley, Martin Cooper, Lynn Corbett, Oran Corey, Julián Coronel, John Corrigan, Rosa Ysabel Cotrina Pereyra, Yves Cottin, Benoit Coutu, Aurel Cracan, Peter Crean, James Crenshaw, Harry J.G.M. Crijns, Charles H. Crump, Fred Cucher, David Cudmore, Lianqun Cui, John E. Culp, Harald Darius, Patrick Dary, Olivier Dascotte, Ira Dauber, Thomas Davee, Ruth Davies, Gershan Davis, Jean‐Marc Davy, Mark Dayer, Axel De La Briolle, Manuel de Mora, Eduardo de Teresa, Luc De Wolf, Eric Decoulx, Sasalu Deepak, Pascal Defaye, Freddy Del‐Carpio Munoz, Diana Delić-Brkljačić, Laurent Deluche, S. Destrac, N. Joseph Deumite, Silvia Di Legge, Olivier Dibon, Igor Diemberger, Jean Guillaume Dillinger, Pedro Dionísio, Stefan Naydenov, Imran Dotani, Elena Dotcheva, Anthony D’Souza, Simon W Dubrey, Xavier Ducrocq, Dmitry Dupljakov, Vuong Duthinh, Óscar Pereira Dutra, Dipankar Dutta, Nathalie Duvilla, Johnny Dy, Rainer Dziewas, Charles B. Eaton, William Eaves, Matthew Ebinger, J.W.M. Eck van, Tim Edwards, Isabel Egocheaga, Clifford Ehrlich, Steven Eisenberg, Abdel El Hallak, Adnan El Jabali, Rami El Mahmoud, Mahfouz El Shahawy, Zayd Eldadah, Fouad Elghelbazouri, Omar Elhag, Mehiar El-Hamdani, Darlene J. Elias, Adam Ellery, Hassan El‐Sayed, Arif Elvan, Bernard Erickson, E Espaliat, Louis Essandoh, Tamara Everington, Rudolph Evonich, Andrey Ezhov, Lorenzo Fácila, Ramin Farsad, Maxime Fayard, Francesco Fedele, Luís Gustavo Gomes Ferreira, Daniel Ferreira, José Santos, Anna Ferrier, Alexandra Vanessa Finsen, Brian First, Raymond Fisher, John C. Floyd, Thomas Folk, Ana Catarina Fonseca, Luísa Fonseca, Steven Forman, Magnus Forsgren, Malcolm Foster,
GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non–vitamin K antagonist oral anticoagulant (NOAC), became available. This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase ...
Elsevier BV

Carla Pauli, Maria Emília Rodrigues de Oliveira Thais, Ricardo Guarnieri, Marcelo Libório Schwarzbold, Alexandre Paim Díaz, Juliana Ben, Marcelo Neves Linhares, Hans J. Markowitsch, Peter Wolf, Samuel Wiebe, Kátia Lin, Roger Walz,
Purpose The purpose of this study was to investigate the following: i) the objective impairment in neuropsychological tests that were associated with the subjective perception of cognitive function decline in Brazilian patients who underwent mesial temporal lobe epilepsy (MTLE) surgery and ii) the predictive variables for those impaired objective neuropsychological tests. Methods Forty-eight adults with MTLE (27 right HS and 23 male) were divided according to their perception of changes (Decline or ...
Tópico(s): Neuroscience and Neuropharmacology Research
2017 - Elsevier BV | Epilepsy & Behavior

Mark William Lopes, Rodrigo Bainy Leal, Ricardo Guarnieri, Marcelo Libório Schwarzbold, Alexandre Ademar Hoeller, Alexandre Paim Díaz, Gustavo Luchi Boos, Kátia Lin, Marcelo Neves Linhares, Jean Costa Nunes, João Quevedo, Z A Bortolotto, Hans J. Markowitsch, Stafford L. Lightman, Roger Walz,
Abstract Glucocorticoids (GC) released during stress response exert feedforward effects in the whole brain, but particularly in the limbic circuits that modulates cognition, emotion and behavior. GC are the most commonly prescribed anti-inflammatory and immunosuppressant medication worldwide and pharmacological GC treatment has been paralleled by the high incidence of acute and chronic neuropsychiatric side effects, which reinforces the brain sensitivity for GC. Synapses can be bi-directionally modifiable ...
Tópico(s): Memory and Neural Mechanisms
2016 - Springer Nature | Translational Psychiatry

Maria Emília Rodrigues de Oliveira Thais, G Cavallazzi, Douglas Affonso Formolo, Lucas D'Ávila de Castro, Roseli Schmoeller, Ricardo Guarnieri, Marcelo Libório Schwarzbold, Alexandre Paim Díaz, Alexandre Hohl, Rui Daniel Prediger, Maria Joana Mäder, Marcelo Neves Linhares, Angelica Staniloiu, Hans J. Markowitsch, Roger Walz,
Objectives Traumatic brain injury ( TBI ) is a main cause of mortality and morbidity. Association studies between hospitalization variables and cognitive impairment after TBI are frequently retrospective, including non‐consecutive patients showing variable degrees of TBI severity, and poor management of missing (drop out) cases. Methods We assessed prospectively the demographic and hospitalization variables of 234 consecutive patients with severe TBI (admission G lasgow C oma S cale [ GCS ] ≤8) and determined ...
Tópico(s): Cardiac Arrest and Resuscitation
2012 - Wiley | Journal of Neuropsychology

V. Guarnieri, Leonardo Biazi, Roberto Marchiori, Alexandre Lago,
The adherence of Platinum thin film on Si/SiO2 wafer was studies using Chromium, Titanium or Alumina (Cr, Ti, Al2O3) as interlayer. The adhesion of Pt is a fundamental property in different areas, for example in MEMS devices, which operate at high temperature conditions, as well as in biomedical applications, where the problem of adhesion of a Pt film to the substrate is known as a major challenge in several industrial applications health and in biomedical devices, such as for example in the stents. ...
Tópico(s): Molecular Junctions and Nanostructures
2014 - Landes Bioscience | Biomatter

Elisângela Barboza da Silva, Denisson Santos, Douglas Alves, Milson dos Santos Barbosa, Regina C. L. Guimarães, Bianca M. S. Ferreira, Ricardo A. Guarnieri, Elton Franceschi, Cláudio Dariva, Alexandre F. Santos, Montserrat Fortuny,
The use of ionic liquids (ILs) as demulsifiers of water-in-crude oil emulsions represents a new field of study. The main purpose of this work is to investigate the effect of five ILs, [C4mim]+[NTf2]−, [C8mim]+[NTf2]−, [C12mim]+[NTf2]−, [C4py]+[NTf2]−, and [C8mim]+[ [OTf]−, and a set of operation parameters on the demulsification process, including the heating type (conventional and microwave), IL concentration (0.74–8.9 μmol/g), effect of alkyl chain length, and effect of cation and anion type on demulsification ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2013 - American Chemical Society | Energy & Fuels

Rita C. B. Lemos, Elisângela B. da Silva, Adélia dos Santos, Regina C. L. Guimarães, Bianca M. S. Ferreira, Ricardo A. Guarnieri, Cláudio Dariva, Elton Franceschi, Alexandre F. Santos, Montserrat Fortuny,
The main objective of this work is to investigate the role of two types of ionic liquids, omimBF4 and omimPF6, upon the microwave demulsification process. A series of batch demulsification runs were carried out to evaluate the final emulsified water content of emulsion samples after the exposure to microwaves at distinct ionic liquid concentrations. Tests were performed in a commercial microwave reactor system, using high stable water-in-crude oil emulsion samples containing different salt and water ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2010 - American Chemical Society | Energy & Fuels

Marcelo Libório Schwarzbold, Alexandre Paim Díaz, Jean Costa Nunes, Daniel Santos Sousa, Alexandre Hohl, Ricardo Guarnieri, Marcelo Neves Linhares, Roger Walz,
Objective: To evaluate the validity and utility of the Hamilton Rating Scale for Depression (HAM-D), Beck Depression Inventory (BDI), and Hospital Anxiety and Depression Scale (HADS) as screening tools for depression after severe traumatic brain injury (TBI). Methods: Forty-six consecutive survivors of severe TBI were evaluated at a median of 15 months after injury. Receiver operating characteristic (ROC) analysis was performed using HAM-D, BDI, and HADS as predictors, and the Structured Clinical Interview ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2014 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry

Alexandre Paim Díaz, Marcelo Libório Schwarzbold, Maria Emília de Oliveira Thais, G Cavallazzi, Roseli Schmoeller, Jean Costa Nunes, Alexandre Hohl, Ricardo Guarnieri, Marcelo Neves Linhares, Roger Walz,
To evaluate predictors of non-return to work (nRTW) among social, demographic, clinical, and psychiatric variables after severe traumatic brain injury (TBI) in a cohort of Brazilian patients.Prospective study. Forty-three community-dwelling individuals treated at a Level I trauma center at the time of TBI were evaluated 18 months after trauma. Measures included DSM-IV-TR criteria for personality changes after TBI and Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) to assess psychiatric ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2014 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry

Carla Pauli, Maria Emília de Oliveira Thais, Lucia Sukys-Claudino, Maria Alice Horta Bicalho, Alexandre Bastos, Ricardo Guarnieri, Jean Costa Nunes, Kátia Lin, Marcelo Neves Linhares, Roger Walz,
PurposeThe identification of variables associated with health-related quality of life (HRQoL) in patients with mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) would improve surgical decision-making and post-operatory follow-up in this group of patients.MethodsWe analyzed the independent association between the Quality of Life in Epilepsy Inventory—31 (QOLIE-31) of 81 consecutive patients with refractory MTLE-HS. The clinical, demographic, radiological and electrophysiological ...
Tópico(s): Neuroscience and Neuropharmacology Research
2012 - Elsevier BV | Epilepsy & Behavior

Rafael Humberto de Carvalho, Adriana Lourenço Soares, Danielle Cristina Barreto Honorato, Paulo D. Guarnieri, Mayka Reghiany Pedrão, Fernanda G. Paião, Alexandre Oba, Elza Iouko Ida, Massami Shimokomaki,
The objective of this study was to report the incidence of pale, soft, and exudative (PSE) turkey breast meat at a commercial plant in southern Brazil and the consequences on the quality of meat processing. This study was subdivided into 2 experiments: I) incidence of PSE meat and II) effects on meat processing. Experiment I: A total of 2610 breast filets were collected, and pH and color were tested. A value of 53.0 was determined using a Minolta lightness test (L*) as the cutoff value for PSE meat ...
Tópico(s): Animal Nutrition and Physiology
2014 - Elsevier BV | LWT

Paula Martins, Daisy Machado, Thaís Holtz Theizen, João Paulo Oliveira Guarnieri, Bruno Gaia Bernardes, Gabriel Piccirillo Gomide, Marcus Alexandre Finzi Corat, Camilla Abbehausen, José Luiz Proença‐Módena, Carlos Fernando Odir Rodrigues Melo, Karen Noda Morishita, Rodrigo Ramos Catharino, Clarice Weis Arns, Marcelo Lancellotti,
Abstract The increase of Zika virus (ZIKV) infections in Brazil in the last two years leaves a prophylactic measures on alert for this new and emerging pathogen. Concerning of our positive experience, we developed a new prototype using Neisseria meningitidis outer membrane vesicles (OMV) on ZIKV cell growth in a fusion of OMV in the envelope of virus particles. The fusion of nanoparticles resulting from outer membrane vesicles of N . meningitidis with infected C6/36 cells line were analyzed by Nano ...
Tópico(s): Bacterial Infections and Vaccines
2018 - Nature Portfolio | Scientific Reports

Lauro Wichert‐Ana, Tonicarlo Rodrigues Velasco, Vera C. Terra, Veriano Alexandre, Ricardo Guarnieri, Roger Walz, Mery Kato, Whemberton Martins de Araújo, Carlos Gilberto Carlotti, David Araújo, Antônio Carlos dos Santos, Américo Ceiki Sakamoto,
Typical (TPP) and atypical (APP) perfusion patterns (PP) may be seen in ictal SPECT of patients with temporal lobe epilepsy (TLE). APP may pose problem in the lateralization of the epileptogenic zone (EZ). We aimed to investigate predictive variables for the occurrence of TPP and APP.Fifty-one TLE patients were submitted to successful anterior-mesial temporal lobectomy. Univariate (UVA) and multivariate (MVA) analysis were performed upon clinical data, distribution of interictal spikes, and ictal chronology ...
Tópico(s): Ion Transport and Channel Regulation
2003 - Elsevier BV | Seizure

Alexandre Paim Díaz, Marcelo Libório Schwarzbold, Ricardo Guarnieri, Maria Emília Rodrigues de Oliveira Thais, Alexandre Hohl, Jean Costa Nunes, Marcelo Neves Linhares, Rui Daniel Prediger, Roger Walz,
Personality changes are one of the most prevalent neuropsychiatric impairments following severe traumatic brain injury (TBI) and are related to significant functional impairment, caregiver burden, direct and indirect costs 1. According to the Diagnostic and Statistical Manual of Mental Disorders IV – Text Revision (DSM-IV-TR), personality changes are characterized “by a marked change in personality style and traits from a previous level of functioning. Patients must show evidence of a causative organic ...
Tópico(s): Cardiac Arrest and Resuscitation
2014 - Wiley | CNS Neuroscience & Therapeutics

Ricardo Guarnieri, Jorge Hallak, Roger Walz, Tonicarlo Rodrigues Velasco, Veriano Alexandre Júnior, Vera C. Terra, Lauro Wichert‐Ana, Américo Ceiki Sakamoto,
A epilepsia é uma das causas mais comuns de incapacidade funcional. Comorbidades psiquiátricas, como as psicoses, estão freqüentemente associadas à epilepsia. Psicoses na epilepsia (PNE) requerem tratamento farmacológico mais cuidadoso, levando-se em conta a propensão dos antipsicóticos (AP) em provocar crises convulsivas e o risco de interação farmacocinética com as drogas antiepilépticas (DAE). Após uma breve descrição da classificação e das principais características clínicas das PNE, foram discutidos ...
Tópico(s): Neurological disorders and treatments
2004 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry

Felipe Marín, Adriano Fagali de Souza, Alexandre Mikowski, Luís Henrique Guarnieri Fontanella, Paulo Soares, Luís Norberto López de Lacalle,
Abstract The hybrid manufacturing procedure of combining an initial machining process and a posterior laser powder bed fusion (LPBF) process opens a new range of possibilities for manufacturing complex parts, promising to reduce both costs and printing time. Hence, the first portion of the part might be manufactured by machining, which is used as the substrate for the LPBF. Different manufacturing processes produce a melting interface zone (MIZ) that can affect the mechanical properties of hybrid ...
Tópico(s): Manufacturing Process and Optimization
2022 - Springer Science+Business Media | International Journal of Precision Engineering and Manufacturing-Green Technology

Rafael Humberto de Carvalho, Danielle Cristina Barreto Honorato, Paulo D. Guarnieri, Adriana Lourenço Soares, Mayka Reghiany Pedrão, Alexandre Oba, Fernanda G. Paião, Elza Iouko Ida, Massami Shimokomaki,
The poultry industry suffers losses from problems as pale, soft and exudative (PSE), and dark, firm and dry (DFD) meat can develop in meat as a result of short- and long-term stress, respectively. These abnormalities are impacted by pre-slaughter animal welfare. This work evaluated the effects of open vehicle container microclimate, throughout the 38 ± 10 km journey from the farm to the slaughterhouse, on commercially turkey transported during the Brazilian winter season. The journey was initiated immediately ...
Tópico(s): Effects of Environmental Stressors on Livestock
2017 - Korean Society of Animal Sciences and Technology | Journal of Animal Science and Technology

Cristiane Ribeiro de Carvalho, Mark William Lopes, Leandra C. Constantino, Alexandre Ademar Hoeller, Hiago Murilo Melo, Ricardo Guarnieri, Marcelo Neves Linhares, Zuner A. Bortolotto, Rui Daniel Prediger, Alexandra Latini, Kátia Lin, Júlio Licinio, Rodrigo Bainy Leal, Roger Walz,
We demonstrate that the rate of extracellular signal-related kinase phosphorylation (P-ERK1,2/Total-ERK1,2) in the amygdala is negatively and independently associated with anxiety symptoms in 23 consecutive patients with drug-resistant mesial temporal lobe epilepsy that was surgically treated. In naive Wistar rats, the P-ERK1,2/Total-ERK1,2 ratio in the amygdala correlates negatively with innate anxiety-related behavior on the elevated plus maze (n = 20) but positively with expression of defensive-learned ...
Tópico(s): Receptor Mechanisms and Signaling
2021 - Springer Nature | Molecular Psychiatry

Érica R. Coimbra, Karinne Rezek, Sara Escorsi‐Rosset, Michele Christine Landemberger, Rosa Maria R.P.S. Castro, Michelle Nave Valadão, Ricardo Guarnieri, Tonicarlo Rodrigues Velasco, Vera C. Terra, Marino M. Bianchin, Lauro Wichert‐Ana, Veriano Alexandre, Helena Brentani, Vilma R. Martins, Américo Ceiki Sakamoto, Roger Walz,
Cognitive impairment has long been recognized in people with medically refractory epilepsies. Mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS), the most common surgically remediable epileptic syndrome, has been associated with a cellular prion protein (PrPc) gene (Prnp) variant allele at codon 171. The polymorphism consisting of a methionine-for-valine substitution at codon 129 has been associated with early cognitive deterioration in elderly people and patients with Down syndrome. ...
Tópico(s): Trace Elements in Health
2006 - Elsevier BV | Epilepsy & Behavior

Ricardo Guarnieri, Lauro Wichert‐Ana, Jaime E. C. Hallak, Tonicarlo Rodrigues Velasco, Roger Walz, Mery Kato, Veriano Alexandre, Vera C. Terra, Marino M. Bianchin, Antônio Waldo Zuardi, J.F.W. Deakin, Américo Ceiki Sakamoto,
Psychosis is commonly observed in patients with mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS). Interictal single photon emission computed tomography (SPECT) was performed to compare regional cerebral blood flow (rCBF) pattern of MTLE-HS patients with psychosis of epilepsy (POE) comorbidity and MTLE-HS patients without any psychiatric disorders (Control group). For this, 21 patients with POE and 23 Control patients were matched by educational level, clinical, demographic, electrophysiological, ...
Tópico(s): Neuroscience and Neuropharmacology Research
2005 - Elsevier BV | Psychiatry Research Neuroimaging

Ricardo Guarnieri, David Araújo, Carlos Gilberto Carlotti, João Alberto Assirati, Jaime E. C. Hallak, Tonicarlo Rodrigues Velasco, V. Alexandre, Vera C. Terra, Roger Walz, Marino M. Bianchin, Lauro Wichert‐Ana, Maria Beatriz Martins Linhares, Charles L. Dalmagro, Luciana Midori Inuzuka, Américo Ceiki Sakamoto,
We report two male patients with medically intractable epilepsy and obsessive–compulsive disorder (OCD) symptoms. Both patients experienced remission of obsessive–compulsive symptoms after surgical treatment of epilepsy. Although the surgeries targeted different brain regions, the two patients had in common unilateral anterior cingulate cortex ablation. On the basis of these observations, we discuss the pathophysiology of OCD symptoms, emphasizing the role of corticosubcortical pathways in their ...
Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
2005 - Elsevier BV | Epilepsy & Behavior

Ricardo Guarnieri, Roger Walz, Jaime E. C. Hallak, Érica R. Coimbra, Edna de Almeida, Maria P. Cescato, Tonicarlo Rodrigues Velasco, Veriano Alexandre, Vera C. Terra, Carlos Gilberto Carlotti, João Alberto Assirati, Américo Ceiki Sakamoto,
Clinical and demographic presurgical variables may be associated with unfavorable postsurgical neurological outcome in patients with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). However, few reports include preoperative psychiatric disorders as a factor predictive of long-term postsurgical MTLE-HS neurological outcome. We used Engel's criteria to follow 186 postsurgical patients with MTLE-HS for an average of 6 years. DSM-IV criteria and psychiatric comorbidity criteria specific ...
Tópico(s): Neurological disorders and treatments
2009 - Elsevier BV | Epilepsy & Behavior