Portal de Periódicos da CAPES

Ophelia Aubert, Dojin Yoo, David Zielinski, Christian Jacquelinet, Emanuele Cozzi, Beatriz Domínguez‐Gil, M. I. Da Silva, Ville Sallinen, Karsten Midtvedt, Camila Ulloa, Franz Immer, David Hartell, Annemarie Weißenbacher, Nikolina Bašić‐Jukić, Kazuhiro Tanabe, Georgia Menoudakou, Helena Teofilo Ferreira da Silva, John Forsythe, Peter P. Reese, Simone Vogelaar, Vassilios Papalois, Alexandre Loupy,

Tópico(s): Reconstructive Surgery and Microvascular Techniques

2021 - Springer Science+Business Media | Transplant International

Steven R. H. Beach, Gene H. Brody, Alexandre A. Todorov, Tracy D. Gunter, Robert A. Philibert,

... authorGene H. Brody, Gene H. Brody University of Georgia, Athens, GASearch for more papers by this authorAlexandre A. Todorov, Alexandre A. Todorov Department of Psychiatry, Washington University, St. ... authorGene H. Brody, Gene H. Brody University of Georgia, Athens, GASearch for more papers by this authorAlexandre A. Todorov, Alexandre A. Todorov Department of Psychiatry, Washington University, St. ...

Tópico(s): Child and Adolescent Health

2009 - Wiley | American Journal of Medical Genetics Part B Neuropsychiatric Genetics

Feng Zhang, Georgia Zarkada, Jinah Han, Jinyu Li, Alexandre Dubrac, Roxana Ola, Gaël Genet, Kevin Boyé, P Michon, Steffen E. Künzel, João Paulo Camporez, Abhishek K. Singh, Guo‐Hua Fong, Michael Simons, Patrick Tso, Carlos Fernández‐Hernando, Gerald I. Shulman, William C. Sessa, Anne Eichmann,

Zipping up obesity Chylomicrons are specialized particles that carry dietary fats from the intestine to the bloodstream for absorption into the body. Lacteals are lymphatic vessels that act as the highway for chylomicron transport, but it is unclear how passage occurs. Zhang et al. report that two endothelial cell receptors, neuropilin-1 (NRP1) and vascular endothelial growth factor receptor 1 (VEGFR1, also known as FLT1), are required to convert the entry spaces between lacteals from open junctions ...

Tópico(s): Dietary Effects on Health

2018 - American Association for the Advancement of Science | Science

Craig S. Anderson, Yining Huang, Richard I. Lindley, Xiaoying Chen, Hisatomi Arima, Guofang Chen, Qiang Li, Laurent Billot, Candice Delcourt, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, Alice C. Durham, Pablo M. Lavados, Tsong-Hai Lee, Christopher Levi, Sheila Cristina Ouriques Martins, Verónica V. Olavarría, Jeyaraj Pandian, Mark Parsons, Octávio Marques Pontes‐Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Federico Silva, Lili Song, Trung Quoc Nguyen, Joanna M. Wardlaw, Ji-Guang Wang, Xia Wang, Mark Woodward, John Chalmers, Thompson Robinson, Craig S. Anderson, Yining Huang, Richard I. Lindley, Xiaoying Chen, Hisatomi Arima, Guofang Chen, Qiang Li, Laurent Billot, Candice Delcourt, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, Alice C. Durham, Pablo M. Lavados, Tsong‐Hai Lee, Christopher Levi, Sheila Cristina Ouriques Martins, Verónica V. Olavarría, Jeyaraj Pandian, Mark Parsons, Octávio Marques Pontes‐Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Federico Silva, Lili Song, Trung Quoc Nguyen, Joanna M. Wardlaw, Ji‐Guang Wang, Xia Wang, Mark Woodward, John Chalmers, Thompson Robinson, Jong S. Kim, Christian Stapf, R. J. Simes, Graeme J. Hankey, Peter Sandercock, Marie‐Germaine Bousser, Ka Sing Wong, Anish Scaria, Yoichiro Hirakawa, Tom J. Moullaali, Cheryl Carcel, P. J. Gordon, Sully X. Fuentes-Patarroyo, Dino Benito, Ruiqi Chen, Yongjun Cao, Amy Kunchok, Stephen L. Winters, Shelagh B. Coutts, Sohei Yoshimura, Shoujiang You, Jie Yang, Guojun Wu, Shi‐Hong Zhang, Lisa Manning, Amit Mistri, Victoria J. Haunton, Jatinder S. Minhas, Alejandra Malavera, Joyce Lim, Leibo Liu, Namrata N. Kumar, Nicole Tay, Kerry Jenson, Sarah Richtering, Sharon Tucker, Elizabeth Knight, Elizaveta Ivanova, Emma Thembani, E. Odgers, Elizabeth A. Sanders, Sabrina Small, Ruchita Vaghasiya, Manuela Armenis, Paul S. Donnelly, Merza Ahmad Baig, N. J. Blacklock, B. Naidu, Helen Monaghan, Phillipa Smith, Parisa Glass, Xuejie Bai, Qiancheng Li, Pingping Zhu, Liang Kong, Ruihong He, He Zhao, Jiajie Lv, Haijing Jia, Zhen Xi, Yuhan Cong, Buliang Cui, Hua Deng, Ying Guo, L He, Ruolan Jia, Nan Li, Wei Li, Mengxiao Liu, Meng Zhang, Ziwei Xu, Ting Zhang, Yan Zhao, Philip D. Gregory, Yunjeong In, Su Kim, Jung Eun Ahn, Sul Hwa Kim, Young Lan Hong, Francisca González-McCawley, Magda Carla Ouriques Martins, Bernardita Portales, Ching‐Yi Wang, S J Ryu, Hardeep Aujla, Sue Lewin, Tracy Kumar, Sara Barrows, Ahtasam Ebraimo, Hong Ha Uyen, Nguyen Anh Giang, Le Thi My Linh, Lê Thị Thuý An, Do Minh Phuong, Pham Vu Bich Ngoc, Nguyen Mai Hang, Nguyen Thi Bich Tran, Ha Thi Thu Hien, Mai Bao Yen, Ngo Thuy Tram, Tran Thi Thanh Truc, Nguyen A. Hoa, Nguyen T.B. Thuan, HA THI KIM OANH, Deepti Arora, Shweta Jain Verma, Martín Krause, Miriam Priglinger, Susan Day, S. Jala, Lucy Davies, Emma Ray, S. Celestino, Linda Law, Tissa Wijeratne, G. André Ng, Ken Nagao, Gary Weiss, N.F. Titton, C. Batista, Zan Ding, Leonardo Augusto Carbonera, Kathleen Ferreira, Ricardo Lessa de Castro, R.K. Martins Filho, Marcelo Addas‐Carvalho, Milena C Libardi, Gustavo Miranda Martins, D. Leite Fagundes, Gabriel Baron, A. Boehringer, José‐Joel González‐Barbosa, Rodrigo Bazán, Geórgia de Carvalho Braga, Gustavo José Luvizutto, Priscila Watson Ribeiro, Fernanda Cristina Winckler, Carla Heloísa Cabral Moro, Alexandre Luiz Longo, R. Liberato, Roberto Ramos Barbosa, Pedro Magalhães, M. Portal, Kevin Martin, Andressa de Souza, Daissy Liliana Mora Cuervo, Daniel Perin, Lucas Miranda Marques, Fernanda Oliveira, Marco Battaglini, F. Lourenço, Kathleen Ferreira, G. Silva, Luís Duarte, Marta Alves, João Carlos Sousa, M. Uhehara, Alejandro M. Brunser, Enrico Mazzon, M. Spencer, Indrani Acosta, A. Rojo, R. Rivas, C Klapp, L. Carvallo, P. Carvallo, Eloy Mansilla, J. Flores, M. Alvarado, Alex F. Herrera, Carolina Reyes, F. Jurado, G. Bustamante, Laura Bravo, José Manuel Matamala, Rodrigo Guerrero, Shuyu Zhou, Ping Li, Wei Liu, L. Liu, Yaohua Tian, Huiling Xu, Jing Wang, Lingling Wang, Zhen Zeng, Lingling Wang, Jinli Zhang, Min Yan, Lei Wang, Qilu Zhang, Tao Xue, Chao Liu, Jie Shi, X. Zhang, L. Tai, Lei Xu, Lu Hua, H. Nie, Xianchan Li, Junshan Zhou, Y. Liu, Ping Gong, Yaohua Tian, H. Zhao, Jinli Zhang, Ruikun Li, Xia Wang, Q. Chen, Yan Li, Longfei Wu, Jinli Zhang, Lijun Jia, Xiaonan Guo, Xianchan Li, Guofeng Chen, Binshan Lin, Wusheng Zhu, Kun Yang, Jinli Zhang, Zheng Zhang, Chenglong Xie, Dawei Wu, Zheng Zhang, Xianchan Li, Yi Wang, D. Liu, Z. Liu, Liming Liang,

Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but the target systolic blood pressure for optimal outcome is uncertain. We assessed intensive blood pressure lowering compared with guideline-recommended blood pressure lowering in patients treated with alteplase for acute ischaemic stroke.We did an international, partial-factorial, open-label, blinded-endpoint trial of thrombolysis-eligible ...

Elsevier BV

4

4

Artigo Acesso aberto Produção Nacional Revisado por pares

Iain Chapple, Brian L. Mealey, Thomas E. Van Dyke, P. Mark Bartold, Henrik Dommisch, Peter Eickholz, Maria L. Geisinger, Robert J. Genco, Michael Glogauer, Moshe Goldstein, Terrence J. Griffin, Palle Holmstrup, Georgia K. Johnson, Yvonne L. Kapila, Niklaus P. Lang, Joerg Meyle, Shinya Murakami, Jacqueline M. Plemons, Giuseppe Alexandre Romito, Lior Shapira, Dimitris N. Tatakis, Wim Teughels, Leonardo Trombelli, Clemens Walter, Gernot Wimmer, Pinelopi Xenoudi, Hiromasa Yoshie,

Abstract Periodontal health is defined by absence of clinically detectable inflammation. There is a biological level of immune surveillance that is consistent with clinical gingival health and homeostasis. Clinical gingival health may be found in a periodontium that is intact, i.e. without clinical attachment loss or bone loss, and on a reduced periodontium in either a non‐periodontitis patient (e.g. in patients with some form of gingival recession or following crown lengthening surgery) or in a ...

Tópico(s): Periodontal Regeneration and Treatments

2018 - Wiley | Journal of Periodontology

5

5

Artigo Acesso aberto Produção Nacional Revisado por pares

Iain Chapple, Brian L. Mealey, Thomas E. Van Dyke, P. Mark Bartold, Henrik Dommisch, Peter Eickholz, Maria L. Geisinger, Robert J. Genco, Michael Glogauer, Moshe Goldstein, Terrence J. Griffin, Palle Holmstrup, Georgia K. Johnson, Yvonne L. Kapila, Niklaus P. Lang, Joerg Meyle, Shinya Murakami, Jacqueline M. Plemons, Giuseppe Alexandre Romito, Lior Shapira, Dimitris N. Tatakis, Wim Teughels, Leonardo Trombelli, Clemens Walter, Gernot Wimmer, Pinelopi Xenoudi, Hiromasa Yoshie,

Periodontal health is defined by absence of clinically detectable inflammation. There is a biological level of immune surveillance that is consistent with clinical gingival health and homeostasis. Clinical gingival health may be found in a periodontium that is intact, i.e. without clinical attachment loss or bone loss, and on a reduced periodontium in either a non-periodontitis patient (e.g. in patients with some form of gingival recession or following crown lengthening surgery) or in a patient with ...

Tópico(s): Periodontal Regeneration and Treatments

2018 - Wiley | Journal Of Clinical Periodontology

Ying Xu, Maree L. Hackett, John Chalmers, Richard I. Lindley, Xia Wang, Qiang Li, Thompson Robinson, Hisatomi Arima, Pablo M. Lavados, Craig S. Anderson, John Chalmers, Craig S. Anderson, Richard I. Lindley, Hisatomi Arima, Yining Huang, Jong Sung Kim, Pablo M. Lavados, Tsong‐Hai Lee, Christopher Levi, Mark Parsons, Sheila Cristina Ouriques Martins, Jeyaraj Pandian, Octávio Marques Pontes‐Neto, Thompson Robinson, Vijay K. Sharma, Nguyen Huy Thang, Shoichiro Sato, Christian Stapf, Ji-Guang Wang, Joanna M. Wardlaw, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, R. J. Simes, Graeme J. Hankey, Peter Sandercock, Marie‐Germaine Bousser, Ka Sing Wong, Laurent Billot, Qiang Li, Anish Scaria, Xia Wang, Yoichiro Hirakawa, Mark Woodward, Richard I. Lindley, Candice Delcourt, Cheryl Carcel, P. J. Gordon, Sully Xiomara Fuentes Patarroyo, Dino Benito, Christopher Levi, Mark Parsons, Hossein Zareie, Yongjun Cao, Amy Kunchok, Stephen L. Winters, Shelagh B. Coutts, Cheryl Carcel, Tom J. Moullaali, Yongjun Cao, Jie Yang, Guojun Wu, Shihong Zhang, Lili Song, Guofang Chen, Thompson Robinson, Lisa Manning, Xiaoying Chen, Joyce Lim, Sharon Tucker, Leibo Liu, Sully Xiomara Fuentes Patarroyo, Penelope Gordon, Sarah Richtering, Xia Wang, Kerry Jenson, Elizabeth Knight, Elizaveta Ivanova, Emma Thembani, E. Odgers, Elizabeth A. Sanders, Sabrina Small, Ruchita Vaghasiya, Manuela Armenis, Paul S. Donnelly, Merza Ahmad Baig, N. J. Blacklock, B. Naidu, Ravinder Singh, Helen Monaghan, Phillipa Smith, Parisa Glass, Zhen Xi, Hua Deng, Buliang Cui, Ying Guo, L He, Ruolan Jia, Nan Li, Wei Li, Mengxiao Liu, Ziwei Xu, Meng Zhang, Ting Zhang, Yan Zhao, Yunjeong In, Su Jin Kim, Jung Eun Ahn, Sul Hwa Kim, Young Lan Hong, Verónica V. Olavarría, Francisca González, Bernardita Portales, Alejandra Malavera, Magda Carla Ouriques Martins, Ching‐Yi Wang, S J Ryu, Alice Durham, Hardeep Aujla, Sue Lewin, Tracy Kumar, Hong Ha Uyen, Nguyen Anh Giang, Le Thi My Linh, Lê Thị Thuý An, Do Minh Phuong, Pham Vu Bich Ngoc, Nguyen Mai Hang, Nguyen Thi Bich Tran, Ha Thi Thu Hien, Mai Bao Yen, Martín Krause, Miriam Priglinger, Susan Day, S. Jala, Eoin O’Brien, Lucy Davies, Candice Delcourt, Cheryl Carcel, T. Paraskevaidis, Craig S. Anderson, Tissa Wijeratne, S. Celestino, Linda Law, G. André Ng, Ken Nagao, Christopher Levi, Mark Parsons, Ferdinand Miteff, Neil J. Spratt, Lara Kaauwai, Sheila Cristina Ouriques Martins, Rosane Brondani, Andréa Garcia de Almeida, Gary M. Weiss, M. Portal, Millene Rodrigues Camilo, Diandra B. Favoretto, Fábio Alves, Francisco Antunes Dias, Clara Barreira, Carla Heloísa Cabral Moro, Alexandre Luiz Longo, R. Liberato, Renata Cavalcante Barbosa, Pedro Magalhães, Rodrigo Bazán, Geórgia de Carvalho Braga, Gustavo José Luvizutto, Priscila Watson Ribeiro, Melanie Polin, Lucas Miranda Marques, Fernanda Oliveira, Marco Battaglini, F. Lourenço, Kathleen Ferreira, G. Silva, Luís Duarte, Marta Alves, João Carlos Sousa, M. Uhehara, Verónica V. Olavarría, Michael Valenzuela, Alejandro M. Brunser, V. Díaz-Tapia, R. Rivas, C Klapp, L. Carvallo, P. Carvallo, G. Bustamante, Laura Bravo, José Manuel Matamala, Rodrigo Guerrero, Eloy Mansilla, J. Flores, M. Alvarado, Alex F. Herrera, Carolina Reyes, G. Chen, Ping Li, Shuyu Zhou, Wei Liu, L. Liu, Yaohua Tian, Z. Li, Z. Chen, Chao Liu, Yongjun Cao, Jie Shi, Shoujiang You, Xiaolei Zhang, J. Wang, Lidan Wang, Lidan Wang, Zhen Zeng, S. Zhang, Jinli Zhang, Min Yan, Lidan Wang, Tao Xue, Qi Zhang, Xiaofeng Zhang, Yan Li, Ruikun Li, Georgina Cheng, Q. Chen, Yi Zhang, Junshan Zhou, Jie Yang, Ying Liu, M.K. Xu, Xu Wei, Rong Li, Huan Liu, Ying Lv, C. Zhang, Xiaolei Zhang, Jun Xia, Hui Wang, Yi Zhang, X. Li, Yi Wang, X. Li, Aiming Lu, Seng Tan, Yu-Wen Huang, Yi Wang, Longfei Wu, Z. Liu, Shiyan Huang, Ya Gao, Longfei Wu, H. Sun, Xiaofeng Zhang, Xinbiao Guo, Ying Lian, Tao Xu, Deqin Geng, Xiao Yan, Dongmin Wang, Naisi Zhao, Jufen Liu, Yuesong Pan, Hui Wang, Z. Wang, Yuanjie Niu, Yi Wang, D. Liu, Wenjun Wu, Hui Wang, Yang Li, Sheng Liu, S. Zhang, D. Wang, Xiangpeng Chang, Jufen Liu, Shuguang Wang, D. Wang, Wenguo Huang, Yuan‐Han Yang, Anna Song, Xiaolei Zhang, Mengchen Zou, Bo Hu, Qianzhou Lv, Lingli Sun, Cong Geng, Lili Song, Hongjian Zhang, Yu‐Peng Wu, Li’an Huang, Yonggang Hao, H. Yan, B. Qiao, A. Zhang,

Seizures after ischemic stroke have not been well-studied. We aim to determine the frequency, determinants, and significance of early seizures after thrombolysis for acute ischemic stroke.Data are from the Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED), an international, multicenter, randomized controlled trial where patients with acute ischemic stroke were randomized to low-dose (0.6 mg/kg) or standard-dose (0.9 mg/kg) IV alteplase. The protocol prespecified prospective ...

Lippincott Williams & Wilkins

Sohei Yoshimura, Richard I. Lindley, Cheryl Carcel, Shoichiro Sato, Candice Delcourt, Xia Wang, John Chalmers, Craig S. Anderson, Hisatomi Arima, Yining Huang, Jong Sung Kim, Pablo M. Lavados, Tsong‐Hai Lee, Christopher Levi, Mark Parsons, Sheila Cristina Ouriques Martins, Jeyaraj Pandian, Octávio Marques Pontes‐Neto, Thompson Robinson, Vijay K. Sharma, Nguyen Huy Thang, Christian Stapf, Ji‐Guang Wang, Joanna M. Wardlaw, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, Laurent Billot, Qiang Li MBiostat, Mark Woodward, P. J. Gordon, Sully Xiomara Fuentes Patarroyo, Dino Benito, Hossein Zareie, Yongjun Cao, Amy Kunchok, Stephen L. Winters, Shelagh B. Coutts, Tom J. Moullaali, Yongjun Cao, Jie Yang, Guojun Wu, Shihong Zhang, Lili Song, Guofang Chen, Lisa Manning, Amit Mistri, Victoria J. Haunton, Xiaoying Chen, Joyce Lim, Sharon Tucker, Leibo Liu, Sully Xiomara Fuentes Patarroyo, Penelope Gordon, Sarah Richtering, Xia Wang, Kerry Jenson, Elizabeth Knight, Elizaveta Ivanova, Emma Thembani, E. Odgers, Elizabeth A. Sanders, Sabrina Small, Ruchita Vaghasiya, Manuela Armenis, Paul S. Donnelly, Merza Ahmad Baig, N. J. Blacklock, B. Naidu, Ravinder Singh, Zhen Xi, Hua Deng, Buliang Cui, Ying Guo, L He, Ruolan Jia, Nan Li, Wei Li, Mengxiao Liu, Ziwei Xu, Meng Zhang, Ting Zhang, Yan Zhao, Yunjeong In, Su Kim, Jung Eun Ahn, Sul Hwa Kim, Young Lan Hong, Verónica V. Olavarría, Francisca González, Bernardita Portales, Alejandra Malavera, Magda Carla Ouriques Martins Taiwan, Ching‐Yi Wang, S J Ryu, Alice Durham, Hardeep Aujla, Sue Lewin, Tracy Kumar Vietnam, Hong Ha Uyen, Nguyen Anh Giang, Le Thi My Linh, Lê Thị Thuý An, Do Minh Phuong, Pham Vu Bich Ngoc, Nguyen Mai Hang, Nguyen Thi Bich Tran, Ha Thi Thu Hien, Mai Bao Yen, Martín Krause, Miriam Priglinger, Susan Day, S. Jala, Linda Davies, Candice Delcourt, Cheryl Carcel, T. Paraskevaidis, Craig S. Anderson, Tissa Wijeratne, S. Celestino, Linda Law, G. André Ng, Christopher Levi, Ken Nagao, Mark Parsons, Ferdinand Miteff, Neil J. Spratt, Lara Kaauwai, Sheila Cristina Ouriques Martins, Rosane Brondani, Arthur Ferraz de Almeida, Gary M. Weiss, Millene Rodrigues Camilo, M. Portal, Diandra B. Favoretto, Fábio Aguiar-Alves, Francisco Antunes Dias, Clara Barreira, Carla Heloísa Cabral Moro, Alexandre Luiz Longo, R. Liberato, Roberto Ramos Barbosa, Pedro Magalhães, Rodrigo Bazán, Geórgia de Carvalho Braga, Gustavo José Luvizutto, Priscila Watson Ribeiro, Melanie Polin, Lucas Miranda Marques, Fernanda Oliveira, Marco Battaglini, F. Lourenço, Kathleen Ferreira, Kattyúcia Cruz Meireles Silva, Luís Duarte, Marta Alves, João de Sousa, M. Uhehara, Verónica V. Olavarría, Michael Valenzuela, Alejandro M. Brunser, V. Díaz-Tapia, R. Rivas, C Klapp, L. Carvallo, P. Carvallo, G. Bustamante, Laura Bravo, José Manuel Matamala, Rodrigo Guerrero, Eloy Mansilla, J. Flores, M. Alvarado, Alex F. Herrera, Carolina Reyes, G. Chen, Ping Li, Shaonan Zhou, Wei Liu, L. Liu, Yaohua Tian, Z. Li, Chen C. Liu, Yiwei Cao, Jie Shi, Shoujiang You, X. Zhang, Jing Wang, Lidan Wang, Lidan Wang, Zhen Zeng, S. Zhang, Xiaofeng Zhang, Min Yan, Lidan Wang, Tao Xue, Qilu Zhang, Xiaofeng Zhang, Yan Li, Ruikun Li, Georgina Cheng, Q. Chen, Yi Zhang, Junshan Zhou, Jean Yang, Ying Liu, Min Xu, Wei Xia, Rong Li, H. Liu, Ying Lv, C. Zhang, X. Zhang, Jun Xia, Hui Wang, Yi Zhang, Xianchan Li, Yi Wang, Xianchan Li, Aiming Lu, Seng Tan, Yining Huang, Yi Wang, Longfei Wu, Z. Liu, Song Huang, Ya Gao, Longfei Wu, H. Sun, Xiaofeng Zhang, Xiaohong Guo, Ying Lian, Tongren Xu, Deqin Geng, Yan Xia, D. Wang, Naisi Zhao, Jufen Liu, Yalan Pan, Hui Wang, Zhiqiang Wang, Yuanjie Niu, Yi Wang, D. Liu, Wei-Sheng Wu, Hui Wang, Lifang Yang, Simin Liu, Shuyang Zhang, D. Wang, Xuexiang Chang, Jufen Liu, Shuguang Wang, D. Wang, Wei Huang, Jean Yang, Anna Song, X. Zhang, Mengchen Zou, Bo Hu, L. Zhou, Lingli Sun, Cong Geng, Lili Song, H. Zhang, Yangfeng Wu, Li-Ting Huang, Yuantao Hao, H. Yan, B. Qiao, A. Zhang, Jean Yang, Ying Liu, Jun Feng, Wen-Jun He, X. Liu, Qinghai Huang, Qing Yang, Wen Zheng, Xincun Zhuang, Xiaoling Chen, H. Nie, Li Li, Xintong Wu, Ting Wu, Bo‐Ying Bao, Yi Wang, Xueliang Zeng, Fang‐Qing Guo, Hancheng Dai, Xu Yang, Yuanhua Shao, X. Zhang, Shun Li, L. Tai,

To determine the optimal cut point on the NIH Stroke Scale (NIHSS) for predicting poor 90-day clinical outcome in patients with supratentorial and infratentorial acute ischemic stroke (AIS).Data are from participants of the alteplase-dose arm of the randomized controlled trial, Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Associations between baseline characteristics of clinically defined supratentorial and infratentorial AIS patients and poor functional outcome, defined ...

Lippincott Williams & Wilkins

Fernanda G. Herrera, Catherine Ronet, Maria Ochoa de Olza, David Barras, Isaac Crespo, Massimo Andreatta, Jesús Corría-Osorio, Aodrenn Spill, Fabrizio Benedetti, Raphaël Genolet, Angela Orcurto, Martina Imbimbo, Eleonora Ghisoni, Blanca Navarro Rodrigo, Dominik Berthold, Apostolos Sarivalasis, Khalil Zaman, Rafael Durán, Clarisse Dromain, John O. Prior, Niklaus Schaefer, Jean Bourhis, Georgia Dimopoulou, Zoi Tsourti, Marius Messemaker, Thomas H. Smith, Sarah Warren, Periklis Foukas, Sylvie Rusakiewicz, Mikaël J. Pittet, Stefan Zimmermann, Christine Sempoux, Urania Dafni, Alexandre Harari, Lana E. Kandalaft, Santiago J. Carmona, Denarda Dangaj, Melita Irving, George Coukos,

Abstract Developing strategies to inflame tumors is critical for increasing response to immunotherapy. Here, we report that low-dose radiotherapy (LDRT) of murine tumors promotes T-cell infiltration and enables responsiveness to combinatorial immunotherapy in an IFN-dependent manner. Treatment efficacy relied upon mobilizing both adaptive and innate immunity and depended on both cytotoxic CD4+ and CD8+ T cells. LDRT elicited predominantly CD4+ cells with features of exhausted effector cytotoxic cells, ...

Tópico(s): Immunotherapy and Immune Responses

2021 - American Association for Cancer Research | Cancer Discovery

Georgia Zarkada, Joel P. Howard, Xue Xiao, Hyojin Park, Mathilde Bizou, Séverine Leclerc, Steffen E. Künzel, Blanche Boisseau, Jinyu Li, Gaël Cagnone, Jean Sébastien Joyal, Grégor Andelfinger, Anne Eichmann, Alexandre Dubrac,

Endothelial tip cells guiding tissue vascularization are primary targets for angiogenic therapies. Whether tip cells require differential signals to develop their complex branching patterns remained unknown. Here, we show that diving tip cells invading the mouse neuroretina (D-tip cells) are distinct from tip cells guiding the superficial retinal vascular plexus (S-tip cells). D-tip cells have a unique transcriptional signature, including high TGF-β signaling, and they begin to acquire blood-retina ...

Tópico(s): Retinal Diseases and Treatments

2021 - Elsevier BV | Developmental Cell

Jackie M. Poos, Amy MacDougall, Esther van den Berg, Lize C. Jiskoot, Janne M. Papma, Emma L. van der Ende, Harro Seelaar, Lucy L. Russell, Georgia Peakman, Rhian S. Convery, Yolande A.L. Pijnenburg, Fermín Moreno, Raquel Sánchez‐Valle, Barbara Borroni, Robert Laforce, Marie-Claire Doré, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Simon Ducharme, Christopher Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Isabelle Le Ber, Florence Pasquier, John C. van Swieten, Jonathan D. Rohrer, Martin N. Rossor, Nick C. Fox, Jason D. Warren, Ione Woollacott, Rachelle Shafei, Carolin Heller, Imogen J. Swift, Katrina Moore, Aitana Sogorb‐Esteve, Annabel Nelson, Arabella Bouzigues, Caroline Greaves, David L. Cash, Hanya Benotmane, Emily Todd, Henrik Zetterberg, Kiran Samra, Martina Bocchetta, Rita Guerreiro, José Brás, David L. Thomas, Jennifer Nicholas, Simon Mead, Lieke Meeter, Jessica Panman, Lucia Giannini, Rick van Minkelen, Myriam Barandiarán, Begoña Indakoetxea, Alazne Gabilondo, Mikel Tainta, María de Arriba, Ana Gorostidi, Miren Zulaica, Jorge Villanúa, Zigor Díaz, Ana Gorostidi, Marta Cañada, Patricia Alves, Sergi Borrego‐Écija, Jaume Olives, Albert Lladó, Mircea Balasa, Anna Antonell, Núria Bargalló, Enrico Premi, Maura Cosseddu, Stefano Gazzina, Alessandro Padovani, Alberto Benussi, Valentina Cantoni, Roberto Gasparotti, Silvana Archetti, Sandra E. Black, Sara Mitchell, Ekaterina Rogaeva, Morris Freedman, Ron Keren, David F. Tang‐Wai, Linn Öijerstedt, Christin Andersson, Vesna Jelić, Håkan Thonberg, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Thomas Cope, Carolyn Timberlake, Timothy Rittman, Christen Shoesmith, Robert Bartha, Rosa Rademakers, Carlo Wilke, Lisa Graf, H.‐O. Karnath, Benjamin Bender, Rose Bruffaerts, Philip Van Damme, Mathieu Vandenbulcke, Annick Vogels, Koen Poesen, Catarina B. Ferreira, Gabriel Miltenberger, Frederico Simões do Couto, Carolina Maruta, Ana Verdelho, Sónia Afonso, Ricardo Taipa, Paola Caroppo, Giuseppe Di Fede, Giorgio Giaccone, Sara Prioni, Veronica Redaelli, Giacomina Rossi, Diana Duro, Maria Rosário Almeida, Miguel Castelo‐Branco, Maria João Leitão, Miguel Tábuas‐Pereira, Beatriz Santiago, Serge Gauthier, Pedro Rosa‐Neto, Michele Veldsman, Paul Thompson, Tobias Langheinrich, Catharina Prix, Tobias Hoegen, Elisabeth Wlasich, Sandra Loosli, Sonja Schönecker, Elisa Semler, Sarah Anderl‐Straub, Jolina Lombardi, Benedetta Nacmias, Camilla Ferrari, Cristina Polito, Gemma Lombardi, Valentina Bessi, Agnès Camuzat, Alexis Brice, Anne Bertrand, Aurélie Funkiewiez, Daisy Rinaldi, Dario Saracino, Olivier Colliot, Sabrina Sayah, Adeline Rollin, Grégory Kuchcinski, Maxime Bertoux, Thibaud Lebouvier, Vincent Deramecourt,

Disease-modifying therapeutic trials for genetic frontotemporal dementia (FTD) are underway, but sensitive cognitive outcome measures are lacking. The aim of this study was to identify such cognitive tests in early stage FTD by investigating cognitive decline in a large cohort of genetic FTD pathogenic variant carriers and by investigating whether gene-specific differences are moderated by disease stage (asymptomatic, prodromal, and symptomatic).C9orf72, GRN, and MAPT pathogenic variant carriers as ...

Tópico(s): Alzheimer's disease research and treatments

2022 - Lippincott Williams & Wilkins | Neurology

Julio C. Rojas, Ping Wang, Adam M. Staffaroni, Carolin Heller, Yann Cobigo, Amy Wolf, Sheng‐Yang M. Goh, Peter A. Ljubenkov, Hilary W. Heuer, Jamie Fong, Joanne Taylor, Eliseo Veras, Linan Song, Andreas Jeromin, David Hanlon, Lili Yu, Arvind Khinikar, Rajeev Sivasankaran, Agnieszka Kieloch, Marie‐Anne Valentin, Anna M. Karydas, Laura L. Mitic, Rodney Pearlman, John Kornak, Joel H. Kramer, Bruce L. Miller, Kejal Kantarci, David S. Knopman, Neill R. Graff‐Radford, Leonard Petrucelli, Rosa Rademakers, David J. Irwin, Murray Grossman, Eliana Marisa Ramos, Giovanni Coppola, Mario F. Mendez, Yvette Bordelon, Bradford C. Dickerson, Nupur Ghoshal, Edward D. Huey, Ian R. Mackenzie, Brian S. Appleby, Kimiko Domoto‐Reilly, Ging‐Yuek Robin Hsiung, Arthur W. Toga, Sandra Weıntraub, Daniel Kaufer, Diana Kerwin, Irene Litvan, Chiadikaobi Onyike, Alexander Pantelyat, Erik D. Roberson, Maria Carmela Tartaglia, Tatiana Foroud, Weiping Chen, Julie Czerkowicz, Danielle Graham, John C. van Swieten, Barbara Borroni, Raquel Sánchez‐Valle, Fermín Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Christopher Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Sandro Sorbi, David M. Cash, Rhian S. Convery, Martina Bocchetta, Martha Foiani, Caroline Greaves, Georgia Peakman, Lucy L. Russell, Imogen J. Swift, Emily Todd, Jonathan D. Rohrer, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer,

We tested the hypothesis that plasma neurofilament light chain (NfL) identifies asymptomatic carriers of familial frontotemporal lobar degeneration (FTLD)-causing mutations at risk of disease progression.Baseline plasma NfL concentrations were measured with single-molecule array in original (n = 277) and validation (n = 297) cohorts. C9orf72, GRN, and MAPT mutation carriers and noncarriers from the same families were classified by disease severity (asymptomatic, prodromal, and full phenotype) using the CDR ...

Tópico(s): Parkinson's Disease Mechanisms and Treatments

2021 - Lippincott Williams & Wilkins | Neurology

Yves Lévy, Christine Lacabaratz, Kim Ellefsen-Lavoie, Wolfgang Stöhr, Jean‐Daniel Lelièvre, Pierre‐Alexandre Bart, Odile Launay, Jonathan Weber, Bernd Salzberger, Aurélie Wiedemann, Mathieu Surénaud, David M. Koelle, Hans Wolf, Ralf Wagner, Véronique Rieux, David C. Montefiori, Nicole L. Yates, Georgia D. Tomaras, Raphaël Gottardo, Bryan T. Mayer, S.-W Ding, Rodolphe Thiébaut, Sheena McCormack, Geneviève Chêne, Giuseppe Pantaleo,

DNA vectors have been widely used as a priming of poxvirus vaccine in prime/boost regimens. Whether the number of DNA impacts qualitatively or quantitatively the immune response is not fully explored. With the aim to reinforce T-cell responses by optimizing the prime-boost regimen, the multicentric EV03/ANRS VAC20 phase I/II trial, randomized 147 HIV-negative volunteers to either 3xDNA plus 1xNYVAC (weeks 0, 4, 8 plus 24; n = 74) or to 2xDNA plus 2xNYVAC (weeks 0, 4 plus 20, 24; n = 73) groups. T-cell ...

Tópico(s): Herpesvirus Infections and Treatments

2020 - Public Library of Science | PLoS Pathogens

Jon S. Matsumura, Kevin T. Stroupe, Frank A. Lederle, Tassos C. Kyriakides, Ling Ge, Julie A. Freischlag, Erika R. Ketteler, Darra D. Kingsley, John Marek, Richard J. Massen, Brian Matteson, John D. Pitcher, Mark Langsfeld, John D. Corson, James M. Goff, Karthnik Kasirajan, Christina Paap, Diane C. Robertson, Atef A. Salam, Ravi Veeraswamy, Ross Milner, Karthikeshwar Kasirajan, Jane Guidot, Brajesh K. Lal, Steven J. Busuttil, Michael Lilly, Melita Braganza, Kea Ellis, Mark A. Patterson, William D. Jordan, David Whitley, Steve M. Taylor, Marc A. Passman, Donna Kerns, Cindy Inman, Jennifer Poirier, James L. Ebaugh, J.D. Raffetto, David K. Chew, Subhash Lathi, Christopher Owens, Kathleen Hickson, Hasan H. Dosluoglu, Karen Eschberger, Melina R. Kibbe, Henry Baraniewski, Jon Matsumura, Michelle Endo, Anna Busman, Wendy Meadows, Mary E. Evans, Joseph S. Giglia, Hosam El Sayed, Amy B. Reed, Madeline Ruf, Stephanie Ross, Jessie Jean-Claude, Gilles Pinault, Preet Kang, Nadine E White, Matthew Eiseman, Reba Jones, Carlos H. Timaran, J. Gregory Modrall, M. Burress Welborn, J.Alonso Lopez, Tammy Nguyen, John K.Y. Chacko, Kenneth Granke, Angela G. Vouyouka, Erin Olgren, Prakash Chand, Brenda Allende, Michael J. Ranella, Claudia Yales, Thomas A. Whitehill, William C. Krupski, Mark R. Nehler, Stephen Johnson, Darrell N. Jones, Pamela K. Strecker, Michelle A. Bhola, Cynthia K. Shortell, John Gray, Jeffrey H. Lawson, Richard L. McCann, Mark Sebastian, Jean Kistler Tetterton, Carla Blackwell, Patricia A. Prinzo, Nina Lee, Frank T. Padberg, Joaquim J. Cerveira, Brajesh K. Lal, Robert W. Zickler, Karen Hauck, Scott A. Berceli, W. Anthony Lee, C. Keith Ozaki, Peter R. Nelson, Anne S. Irwin, Randy Baum, Bernadette Aulivola, Heron E. Rodríguez, Fred N. Littooy, Howard P. Greisler, Mary T. O'Sullivan, Panagiotis Kougias, Peter H. Lin, Ruth L. Bush, Gene Guinn, Catherine Cagiannos, Sherilyn Pillack, Barbara Guillory, Dolores F. Cikrit, Stephen G. Lalka, Gary W. Lemmon, Ryan Nachreiner, Mitzi Rusomaroff, Elaine O’Brien, Joseph J. Cullen, Jamal J. Hoballah, William J. Sharp, Jeanne L. McCandless, Vickie Beach, David J. Minion, Thomas H. Schwarcz, Joy Kimbrough, Laura Ashe, Anna K. Rockich, Jill Warner-Carpenter, Mohammed Moursi, John F. Eidt, Sandra Brock, Christian Bianchi, Vicki Bishop, Ian L. Gordon, Roy M. Fujitani, Stephen M. Kubaska, Mina Behdad, R. Azadegan, Christine Ma Agas, Kathy Zalecki, John R. Hoch, Sandra C. Carr, Charles W. Acher, Margaret L. Schwarze, Girma Tefera, Matthew W. Mell, Beth Dunlap, Janice Rieder, John Stuart, Darryl S. Weiman, Omran Abul-Khoudoud, H. Edward Garrett, Sandra Walsh, Karen L. Wilson, Gary R. Seabrook, Robert A. Cambria, Kellie R. Brown, Brian D. Lewis, Susan Framberg, Christa Kallio, Roderick A. Barke, Steven M. Santilli, Alexandre C. d’Audiffret, Nancy Oberle, Catherine Proebstle, Lauri Lee Johnson, Glenn R. Jacobowitz, Neal S. Cayne, Caron Rockman, Mark A. Adelman, Paul J. Gagne, Matthew M. Nalbandian, Leah J. Caropolo, Iraklis I. Pipinos, Jason M. Johanning, Thomas G. Lynch, Holly DeSpiegelaere, Georgia Purviance, Wei Zhou, Ronald L. Dalman, Jason T. Lee, Bassem Safadi, Sheila M. Coogan, Sherry M. Wren, Doghdoo D. Bahmani, Deanna Maples, Shawna Thunen, Michael A. Golden, Marc Mitchell, Ronald M. Fairman, Sally Reinhardt, Mark A. Wilson, Edith Tzeng, Satish C. Muluk, Nina Peterson, Maria Foster, James M. Edwards, Gregory L. Moneta, Gregory J. Landry, Lloyd M. Taylor, Richard Yeager, Eleanor Cannady, Gerald S. Treiman, Stephanie Hatton-Ward, Barbara Salabsky, Nikhil Kansal, Erik L. Owens, Melanie Estes, Beth A. Forbes, Cinda Sobotta, Joseph H. Rapp, Linda M. Reilly, Sandra L. Perez, Kimberly Yan, Rajaabrata Sarkar, Shelley Dwyer, Ted R. Kohler, Thomas S. Hatsukami, David G. Glickerman, Michael E. Sobel, Thomas S. Burdick, Kimberly Pedersen, Patricia A. Cleary, Nikhil Kansal, Erik L. Owens, Melanie Estes, Beth A. Forbes, Cinda Sobotta, Martin R. Back, Dennis F. Bandyk, Brad Johnson, Murray L. Shames, Rebecca L. Reinhard, Sandra C. Thomas, Glenn C. Hunter, Luis R. Leon, Alex Westerband, Robert J. Guerra, Macario Riveros, John L. Mills, John Hughes, Andréa M. Escalante, Shemuel B. Psalms, Nancy N. Day, Robyn Macsata, Anton N. Sidawy, Jonathan Weiswasser, Subodh Arora, Brenda J. Jasper, Alan Dardik, Vivian Gahtan, Bart E. Muhs, Bauer E. Sumpio, Richard J. Gusberg, Marcelo Spector, Jeffrey Pollak, John Aruny, Eamon Kelly, James Wong, Penny Vasilas, Carmelene Joncas, Hugh A. Gelabert, Christian DeVirgillio, David A. Rigberg, L R Cole,

Prior analysis in the Open vs Endovascular Repair Veterans Affairs (VA) Cooperative Study (CSP #498) demonstrated that survival, quality of life, and total health care costs are not significantly different between the open and endovascular methods of repair of abdominal aortic aneurysm. The device is a major cost of this method of repair, and the objective of this study was to evaluate the costs of the device, abdominal aortic aneurysm repair, and total health care costs when different endograft systems ...

Tópico(s): Vascular Procedures and Complications

Elsevier BV | Journal of Vascular Surgery

Janet T. Powell, Michael Sweeting, Pinar Ulug, J D Blankensteijn, F. Lederle, J-P Becquemin, R M Greenhalgh, R M Greenhalgh, Jonathan Beard, Martin Buxton, Louise Brown, Peter L. Harris, Janet T. Powell, John Rose, I T Russell, Mark Sculpher, Simon G. Thompson, Richard Lilford, Peter Bell, R M Greenhalgh, S. C. Whitaker, PA Poole-Wilson, C V Ruckley, William B. Campbell, Michael R. E. Dean, M.S.T. Ruttley, E C Coles, Janet T. Powell, Alison Halliday, S. Julian Gibbs, Louise Brown, David Epstein, Mark Sculpher, Simon G. Thompson, R.J. Hannon, Lynn C. Johnston, Andrew W. Bradbury, Michael Henderson, S D Parvin, David Shepherd, Roger M. Greenhalgh, Adam Mitchell, P. R. Edwards, G. Abbott, D J Higman, A. Vohra, S. Ashley, C Robottom, Mike Wyatt, John Rose, David J. Byrne, Richard Edwards, D P Leiberman, D H McCarter, Peter R. Taylor, John Reidy, A R Wilkinson, Duncan F. Ettles, A E Clason, G.L.S. LEEN, N. Wilson, Mark Downes, Stuart Walker, Janet Lavelle, M.J. Gough, Simon McPherson, D J A Scott, D O Kessell, Ross Naylor, R.D. Sayers, N.G. Fishwick, Peter L. Harris, Debby Gould, Michael G. Walker, NATE CHALMERS, A. Garnham, Michael Collins, Jonathan Beard, P.A. Gaines, Ashour Michael, Raman Uberoi, B.D. Braithwaite, Simon C. Whitaker, Jonathan N. Davies, Simon Travis, George Hamilton, Andrew Platts, A A Shandall, Brian A. Sullivan, Mohammed S. Sobeh, Matthew Matson, A.D. Fox, R. Orme, W Yusef, Timothy C. Doyle, M Horrocks, John Hardman, Paul Blair, Peter K. Ellis, Gordon A. Morris, A. Odurny, Rajiv Vohra, Martin Duddy, Matt Thompson, T M Loosemore, Antonio Belli, Robert Morgan, M Adiseshiah, Jocelyn Brookes, C N McCollum, Raymond Ashleigh, M. Aukett, Sara Baker, Ellis Barbé, N Batson, Jocelyn Bell, John E. Blundell, Dee Boardley, Simon Boyes, Oliver Brown, J. Bryce, Martin D. Carmichael, Tina Chance, Jonathan Coleman, C Cosgrove, G. Curran, Thomas H. Dennison, Carol Devine, Nikki Dewhirst, Belinda Errington, H Farrell, Charles Fisher, Paul Fulford, Michael J. Gough, Carol Graham, Richard Hooper, G. O. Horne, L. A. Horrocks, B Hughes, Tim Hutchings, Monisha Das, Ciaran Judge, Louise Kelly, John D. Kemp, Amy C. Kite, Milja Kivelä, Michelle Lapworth, Cheong Lee, L Linekar, Asif Mahmood, Lyn March, Julio Ellacuriaga San Martin, N Matharu, K McGuigen, P Morris-Vincent, Stephen Murray, Ann Marie Murtagh, Gareth Owen, Virin Ramoutar, Christine Rippin, J M Rowley, Julia Sinclair, Sarah Spencer, V Taylor, Christopher Tomlinson, Sue Ward, Vera Wealleans, Jason R. West, Katie White, John P. Williams, L Wilson, D. E. Grobbee, J D Blankensteijn, Aneta Bąk, Jaap Buth, Peter M. T. Pattynama, E L G Verhoeven, A E van Voorthuisen, J D Blankensteijn, Ron Balm, Jaap Buth, Philippe W.M. Cuypers, D. E. Grobbee, Monique Prinssen, Marc R.H.M. van Sambeek, E L G Verhoeven, Annette F. Baas, M. G. Myriam Hunink, J M van Engelshoven, Michael J. Jacobs, Bas A.J.M. de Mol, J. Hajo van Bockel, Ron Balm, Jim A. Reekers, Xander Tielbeek, E L G Verhoeven, Willem Wisselink, N. Boekema, L.M. Heuveling, I. Sikking, Monique Prinssen, Ron Balm, J D Blankensteijn, Jaap Buth, Philippe W.M. Cuypers, Marc R.H.M. van Sambeek, E L G Verhoeven, Jorg L. de Bruin, Annette F. Baas, J D Blankensteijn, Monique Prinssen, Erik Buskens, Jacob Buth, Alexander V. Tielbeek, J D Blankensteijn, Ron Balm, Jim A. Reekers, Marc R.H.M. van Sambeek, Peter M. T. Pattynama, E L G Verhoeven, Taco Jan Prins, Arie C. van der Ham, J.J.I.M. van der Velden, Steven M.M. van Sterkenburg, G.B. ten Haken, C.M.A. Bruijninckx, Hans van Overhagen, R.P. Tutein Nolthenius, Tadek R. Hendriksz, Joep A.W. Teijink, Henk F. Odink, A.A.E.A. de Smet, Dammis Vroegindeweij, R.M.M. van Loenhout, Matthieu Rutten, Jaap F. Hamming, L. E. H. Lampmann, M.H. Bender, Hella Pasmans, A.C. Vahl, C de Vries, A. J. C. Mackaay, L.M.C. van Dortmont, A.J. van der Vliet, Leo J. Schultze Kool, J.H.B. Boomsma, H.R. van Dop, J.C.A. de Mol van Otterloo, T.P.W. de Rooij, T.M. Smits, Ercüment Yılmaz, Willem Wisselink, F.G. van den Berg, Michel J T Visser, E van der Linden, Geert Willem H. Schurink, Mariëtte de Haan, H.J. Smeets, P. Stabel, F. Van Elst, J Poniewierski, Frank Vermassen, F. Lederle, Julie A. Freischlag, Ted R. Kohler, E Latts, Junya Matsumura, Frank T. Padberg, Tassos C. Kyriakides, Kristi M. Swanson, Peter Guarino, Peter Peduzzi, Michele Antonelli, Clinton Cushing, Elizabeth A. Davis, Lydia Durant, Susan J. Joyner, Alice Kossack, Tassos C. Kyriakides, Mary LeGwin, V. A. McBride, Thomas P. O’Connor, Joanne Poulton, Samuel J. Stratton, Stephen R. Zellner, Amanda J. Snodgrass, Julie Thornton, Kristi M. Swanson, Clair Haakenson, Kevin T. Stroupe, Yvonne Jonk, J W Hallett, Norman Hertzer, Jonathan Towne, David A. Katz, T. Karrison,

Abstract Background The erosion of the early mortality advantage of elective endovascular aneurysm repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a satisfactory explanation. Methods An individual-patient data meta-analysis of four multicentre randomized trials of EVARversus open repair was conducted to a prespecified analysis plan, reporting on mortality, aneurysm-related mortality and reintervention. Results The analysis included 2783 patients, with 14 245 person- ...

Oxford University Press

Laurent Peyrin‐Biroulet, Jean‐François Rahier, Julien Kirchgesner, Véred Abitbol, Sebastian Shaji, Alessandro Armuzzi, Konstantinos Κarmiris, Javier P. Gisbert, Peter Bossuyt, Ulf Helwig, Johan Burisch, Henit Yanai, Glen Doherty, Fernando Magro, Tamás Molnár, Mark Löwenberg, Jonas Halfvarson, Edyta Zagórowicz, Hélène Rousseau, Cédric Baumann, Filip Baert, Laurent Beaugerie, Jean‐Marc Gornet, Laurent Beaugerie, Sebastian Shaji, Laurent Peyrin‐Biroulet, Jean‐Marie Reimund, Xavier Hébuterne, Aurélien Amiot, Franco Armelao, Pierre Blanc, Claudio Papi, Guillaume Pineton de Chambrun, Xavier Roblin, Michael J. J. Chu, Konstantinos Κarmiris, Sohail Shariq, N. Viazis, Jimmy K. Limdi, Piotr Eder H, Georgios Michalopoulos, A. S. Bell, Livia Biancone, Marie Dewitte, Zia Mazhar, Denis Franchimont, Stéphane Nancey, Gilles Macaigne, Mariabeatrice Principi, Mathurin Fuméry, Gareth Parkes, Jean-Christophe Valats, Glen Doherty, Guillaume Bouguen, Tamás Molnár, Hersin Tsai, Mohsin Gangi, Natalia Pedersen, Frédéric Heluwaert, Richard Shenderey, Sebastian Zeißig, Jeffrey Butterworth, Fabiana Castiglione, Lynsey Corless, Camille Zallot, Filip Baert, Salil Singh, Sunil Sonwalkar, Elizabeth Clayton, Jean‐François Rahier, Deven Vani, Guy Bellaïche, Martine De Vos, Julien Kirchgesner, Uri Kopylov, Triana Lobatón, Christophe Locher, Gerassimos J. Mantzaris, George Abouda, Katie Smith, Michael Sprakes, Anǵeliki Theodoropoulou, Emma Wesley, Joëlle Bonnet, David Elphick, Cyrielle Gilletta, John Gordon, David Laharie, A. Nakad, Ambrogio Orlando, Patrick Dubois, Peter Hasselblatt, Christophe Michiels, Cathryn Preston, Anca Staicu, Lucine Vuitton, Mehdi Kaassis, Ally Speight, Deb Ghosh, Mark Löwenberg, Nicolas Mathieu, Anne-Laure Pelletier, Anne Phillips, Fernando Magro, Romain Altwegg, Irit Avni, biron, Jonathon Landy, Maria Nachury, Achuth Shenoy, Caroline Trang, Véred Abitbol, Georgios Bamias, Klaudia Farkas, Christian Maaser, Ariella Bar‐Gil Shitrit, Britta Siegmund, Jérôme Filippi, Colm OʼMorain, Henit Yanai, Laurent Costes, David Hobday, Zoltán Szepes, Emma Calabrese, Helen Dallal, Michael Fung Kee Fung, Arvind Ramadas, Bijay Baburajan, Konrad Koss, Christophe Barberis, Anthony Buisson, Morgane Amil, Paola Balestrieri, Matthew Johnson, Maria Tzouvala, S Viennot, Ferenc Nagy, Nick Thompson, Laurent Alric, Sunil Samuel, Anne Bourrier, Elise Chanteloup, Émilie Del Tedesco, Marcus Harbord, Alan Lobo, Sally Myers, Richard Pollok, Tariq Ahmad, Rubina Chaudhary, Christos Karakoidas, Ashraf Soliman, Carmen Stefănescu, Georgios Theocharis, S Vanden Branden, Belén Beltrán, Yoram Bouhnik, Arnaud Bourreille, Joana C. Branco, Ben Colleypriest, Rami Eliakim, Paul R. Knight, Aoibhlinn O’Toole, Virgina Robles, Konstantinos Triantafyllou, Marta Maia Boscá-Watts, Guy Lambrecht, Lucia Marquez Mosquera, Simon Panter, Aikaterini Pappa, Marion Simon, Ganesh Sivaji, Christophe Bellanger, Arthur Belle, Natalia Borruel, Laurence J. Egan, Harald Peeters, D Sharpstone, Ramesh Arasaradnam, José Manuel Benitez, Jens Frederik Dahlerup, Όλγα Γιουλεμέ, Javier P. Gisbert, Ulf Helwig, Miguel Mínguez, Eftychia Tsironi, Angela Variola, Patrick B. Allen, Lucille Boivineau, Andy Cole, Nina Dib, Fernando Gomollón, Richard L. Johnston, Κωνσταντίνος Κατσάνος, Nicholas A. Kennedy, Marianne Kiszka‐Kanowitz, Ignacio Marín‐Jiménez, Pál Miheller, Pilar Nos, Othman Saraj, Lars Vinter‐Jensen, Eran Zittan, Clotilde Baudry, Xavier Calvet, Marie-Christine Cazelles-Boudier, J L Coenegrachts, Garret Cullen, Marco Daperno, Anjan Dhar, Romain Gérard, Nanna M. Jensen, Nitsan Maharshak, Mark E. McAlindon, Simon Mcloughlin, Miles Parkes, Kamal Patel, Armando Peixoto, Dimitrios Polymeros, Francisco Portela, Rodolfo Rocca, Philippe Marteau, Sreedhar Subramanian, Ruth Tennenbaum, Raja Atreya, Oliver Bachmann, Arthur Berger, Renáta Bor, Maire Buckley, Daniel Carpio, María Chaparro, Francesco Costa, Eugeni Domènech, María Esteve, Stephen F. Foley, Jordi Guardiola, Ioannis E. Κoutroubakis, Tanja Kuehbacher, Cécilia Landman, A. Lavagna, Noemí Manceñido, Míriam Mañosa, María Dolores Martín‐Arranz, Laurianne Plastaras, Maria Lia Scribano, Subhasish Sengupta, Nils Teich, My‐Linh Tran‐Minh, Evanthia Zampeli, Leila Amininejad, Teresa Arroyo, Alain Attar, A Bäckman, Anita Bálint, John Beckly, Shomron Ben‐Horin, Sónia Bernardo, Ludovic Caillo, Bénédicte Caron, María Shanika de Silva, Anna Fábián, Gionata Fiorino, Ana Gutiérrez, Adi Lahat, Mohamed Masmoudi, Marco Mendolaro, Vinciane Muls, Florian Poullenot, C Probert, Cathérine Reenaers, Mariann Rutka, Zaman Sarwari, Joanne Sayer, Beatriz Sicilia, Helena Tavares de Sousa, Catherine Van Kemseke, Yamile Zabana, Marco Astegiano, Paul R. Banim, Dominik Bettenworth, Médina Boualit, Jacob Broder Brodersen, Angeliki Christidou, Rachel Cooney, João Cortez Pinto, Portugal Marília Cravo, Anneline Cremer, Silvio Danese, Antonio Di Sabatino, Jan Fallingborg, Antonio Ferronato, Esther Garcia Planella, Sanjay Gupta, Jonas Halfvarson, Eran Israeli, Samantha Kestenbaum, Lone Larsen, Elisabeth Macken,

There is a need to evaluate the benefit-risk ratio of current therapies in inflammatory bowel disease (IBD) patients to provide the best quality of care. The primary objective of I-CARE (IBD Cancer and serious infections in Europe) was to assess prospectively safety concerns in IBD, with specific focus on the risk of cancer/lymphoma and serious infections in patients treated with anti-tumor necrosis factor and other biologic monotherapy as well as in combination with immunomodulators.I-CARE was designed ...

Elsevier BV

Aurélien Amiot, Jean‐François Rahier, Filip Baert, Stéphane Nahon, Ailsa Hart, N. Viazis, Livia Biancone, Eugeni Domènech, Catherine Reenears, Laurent Peyrin‐Biroulet, Laurent Beaugerie, Johan Burisch, Jean‐Marc Gornet, Laurent Beaugerie, Laurent Peyrin‐Biroulet, Jean-Marie Reimund, Xavier Hébuterne, Aurélien Amiot, Pierre Blanc, Guillaume Pineton de Chambrun, Xavier Roblin, Konstantinos Κarmiris, Sohail Shariq, N. Viazis, Jimmy K. Limdi, Piotr Eder, Georgios Michalopoulos, A. S. Bell, Livia Biancone, Marie Dewitte, Zia Mazhar, Denis Franchimont, Stéphane Nancey, Gilles Macaigne, Mariabeatrice Principi, Mathurin Fuméry, Gareth Parkes, Jean-Christophe Valats, Glen Doherty, Guillaume Bouguen, Tamás Molnár, Hersin Tsai, Mohsin Gangi, Natalia Pedersen, Frédéric Heluwaert, Richard Shenderey, Sebastian Zeißig, Jeffrey Butterworth, Fabiana Castiglione, Lynsey Corless, Camille Zallot, Filip Baert, Salil Singh, Sunil Sonwalkar, Julie Burton, Elizabeth Clayton, Jean‐François Rahier, Deven Vani, R. D’Incà, Guy Bellaïche, Martine De Vos, Julien Kirchgesner, Uri Kopylov, Triana Lobatón, Christophe Locher, Gerassimos J. Mantzaris, George Abouda, Katie Smith, Anǵeliki Theodoropoulou, Emma Wesley, Joëlle Bonnet, David Elphick, Cyrielle Gilletta, John Gordon, David Laharie, A. Nakad, Ambrogio Orlando, Patrick Dubois, Peter Hasselblatt, Christophe Michiels, Cathryn Preston, Anca Staicu, Lucine Vuitton, Mehdi Kaassis, Ally Speight, Deb Ghosh, Mark Löwenberg, Nicolas Mathieu, Anne-Laure Pelletier, Anne Phillips, Fernando Magro, Romain Altwegg, Irit Avni‐Biron, Jonathon Landy, Maria Nachury, Achuth Shenoy, Caroline Trang, Véred Abitbol, Georgios Bamias, Klaudia Farkas, Christian Maaser, Ariella Bar‐Gil Shitrit, Britta Siegmund, Jérôme Filippi, Colm OʼMorain, Henit Yanai, Laurent Costes, David Hobday, Zoltán Szepes, Emma Calabrese, Helen Dallal, Michael Fung Kee Fung, Arvind Ramadas, Bijay Baburajan, Konrad Koss, Christophe Barberis, Anthony Buisson, Morgane Amil, Paola Balestrieri, Matthew Johnson, Maria Tzouvala, S Viennot, Andrew A. Li, Ferenc Nagy, Nick Thompson, Laurent Alric, Sunil Samuel, Anne Bourrier, Elise Chanteloup, Émilie Del Tedesco, Marcus Harbord, Alan Lobo, Sally Myers, Richard Pollok, Tariq Ahmad, Rubina Chaudhary, Christos Karakoidas, Édouard Louis, Ashraf Soliman, Carmen Stefănescu, Georgios Theocharis, S Vanden Branden, Belén Beltrán, Yoram Bouhnik, Arnaud Bourreille, Joana C. Branco, Ben Colleypriest, Rami Eliakim, Paul R. Knight, Aoibhlinn O’Toole, Virgina Robles, Konstantinos Triantafyllou, Marta Maia Boscá-Watts, Guy Lambrecht, Lucia Marquez Mosquera, Simon Panter, Aikaterini Pappa, Marion Simon, Ganesh Sivaji, Christophe Bellanger, Arthur Belle, Natalia Borruel, Laurence J. Egan, Harald Peeters, D Sharpstone, Ramesh Arasaradnam, José Manuel Benitez, Jens Frederik Dahlerup, Όλγα Γιουλεμέ, Javier P Gisbert, Ulf Helwig, Miguel Mínguez, Eftychia Tsironi, Angela Variola, Patrick B. Allen, Lucille Boivineau, Andy Cole, Nina Dib, Fernando Gomollón, Richard L. Johnston, Κωνσταντίνος Κατσάνος, Nicholas A. Kennedy, Marianne Kiszka‐Kanowitz, Ignacio Marín‐Jiménez, Pál Miheller, Pilar Nos, Othman Saraj, Lars Vinter‐Jensen, Eran Zittan, Clotilde Baudry, Xavier Calvet, Marie-Christine Cazelles-Boudier, J L Coenegrachts, Garret Cullen, Marco Daperno, Anjan Dhar, Romain Gérard, Christian Lodberg Hvas, Nanna M. Jensen, Nitsan Maharshak, Mark E. McAlindon, Simon Mcloughlin, Miles Parkes, Kamal Patel, Armando Peixoto, Dimitrios Polymeros, Francisco Portela, Rodolfo Rocca, Philippe Marteau, Sreedhar Subramanian, Ruth Tennenbaum, Raja Atreya, Oliver Bachmann, Arthur Berger, Renáta Bor, Maire Buckley, Daniel Carpio, María Chaparro, Francesco Costa, Eugeni Domènech, María Esteve, Stephen Foley, Jordi Guardiola, Ioannis E. Κoutroubakis, Tanja Kuehbacher, Cécilia Landman, A. Lavagna, Noemí Manceñido, Míriam Mañosa, María Dolores Martín‐Arranz, Laurianne Plastaras, Maria Lia Scribano, Subhasish Sengupta, Nils Teich, My‐Linh Tran‐Minh, Evanthia Zampeli, Leila Amininejad, Teresa Arroyo, Alain Attar, A Bäckman, Anita Bálint, John Beckly, Shomron Ben‐Horin, Sónia Bernardo, Ludovic Caillo, Bénédicte Caron, María Shanika De Silva, Anna Fábián, Gionata Fiorino, Ana Gutiérrez, Adi Lahat, Mohamed Masmoudi, Marco Mendolaro, Vinciane Muls, Florian Poullenot, C Probert, Cathérine Reenaers, Mariann Rutka, Zaman Sarwari, Joanne Sayer, Beatriz Sicilia, Helena Tavares de Sousa, Catherine Van Kemseke, Ana Paula Vieira, Yamile Zabana, Marco Astegiano, Paul R. Banim, Dominik Bettenworth, Médina Boualit, Jacob Broder Brodersen, Angeliki Christidou, Rachel Cooney, João Cortez Pinto, Marília Cravo, Anneline Cremer, Silvio Danese, Antonio Di Sabatino, Jan Fallingborg, Antonio Ferronato, Esther Garcia Planella, Sanjay Gupta, Jonas Halfvarson, Eran Israeli, Samantha Kestenbaum, Lone Larsen, Elisabeth Macken, Nicoletta Μathou, Ágnes Milassin, Joanna Pofelski, Chiara Ricci, Francisco Rodríguez‐Moranta, M. Schmidt-Lauber, Ian Shaw, Marta Gravito‐Soares, Heithem Soliman, Christos Triantos,

Abstract Background and Aims There are concerns regarding the potential impact of the COVID-19 outbreak on patients with inflammatory bowel disease [IBD]. We report on the impact of the COVID-19 outbreak in a European prospective cohort study of patients with IBD Patients and Methods We prospectively collected data from 5457 patients with IBD nested in the ongoing I-CARE project and still followed up in April 2020, with monthly online monitoring of clinical activity, treatment, imaging and endoscopy. ...

Oxford University Press

Masahiro Kanai, Shea J. Andrews, Mattia Cordioli, Christine Stevens, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Akiko Iwasaki, Juha Karjalainen, Juha Mehtonen, Matti Pirinen, Karolina Chwiałkowska, Amy Trankiem, Mary K. Balaconis, Kumar Veerapen, Brooke N. Wolford, Hajar Fauzan Ahmad, Shea J. Andrews, Kathrin Aprile von Hohenstaufen Puoti, Cindy G. Boer, Palwendé Romuald Boua, Guillaume Butler‐Laporte, Carmen L. Cadilla, Karolina Chwiałkowska, Francesca Colombo, Venceslas Douillard, Nicole Dueker, Atanu Kumar Dutta, Yasser M. El‐Sherbiny, Madonna M. Eltoukhy, Sahar Esmaeeli, Annika Faucon, Marie-Julie Favé, Israel Fernández Cadenas, Margherita Francescatto, Laurent C. Francioli, Lude Franke, Macarena Fuentes‐Guajardo, Rocío Gallego Durán, David Gómez-Cabrero, Emi N. Harry, Philip R. Jansen, József Szentpéteri, Elżbieta Kaja, Masahiro Kanai, Chloe Kirk, Athanasios Kousathanas, José Eduardo Krieger, Sanjay Patel, Audrey Lemaçon, Sophie Limou, Píetro Lió, Eirini Marouli, M. Marttila, Carolina Medina‐Gómez, Yael Michaeli, Isabelle Migeotte, Soumyajit Mondal, Andrés Moreno‐Estrada, Leire Moya, Tomoko Nakanishi, Jamal Nasir, Dorote Pasko, Nathaniel M. Pearson, Alexandre C. Pereira, James R. Priest, Vid Prijatelj, Ivana Nedeljković, Alexander Teumer, Réka Várnai, Manuel Romero‐Gómez, Christina Roos, Jeffrey Rosenfeld, Ruolin Li, Eva C. Schulte, Claudia Schurmann, Bahareh Sedaghati-khayat, Doaa Shaheen, Ilangumaran Shivanathan, Csilla Sipeky, Zhou Sirui, Pasquale Striano, Yosuke Tanigawa, Alicia Utrilla Remesal, Nirmal Vadgama, Costanza L. Vallerga, Sander W. van der Laan, Ricardo A. Verdugo, Qingbo Wang, Wei Zhou, Ummu Afeera Zainulabid, Ruth N. Zárate, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Catherine H. Weldon, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Alexander S. Hatoum, Amit Agrawal, Ryan Bogdan, Sarah M. C. Colbert, Wesley K. Thompson, Chun Fan, Emma C. Johnson, Lyudmila Niazyan, Mher Davidyants, Arsen Arakelyan, Diana Avetyan, Makhabbat Bekbossynova, Ainur Tauekelova, Mukhtar Tuleutayev, Aliya Sailybayeva, Yerlan Ramankulov, Elena Zholdybayeva, Jarkyn Dzharmukhanov, Kuat Kassymbek, Tatyana Tsechoeva, Gulsimzhan Turebayeva, Zauresh Smagulova, Timur Muratov, Sadyk Khamitov, Alex S. F. Kwong, Nicholas J. Timpson, Mari Niemi, Souad Rahmouni, Julien Guntz, Y Beguin, Mattia Cordioli, Sara Pigazzini, Lindokuhle Nkambule, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Stéphanie Gofflot, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Nicky Tiembe, David Morrison, Jonathan Afilalo, Vincent Mooser, J. Brent Richards, Simon Rousseau, Madéleine Durand, Guillaume Butler‐Laporte, Vincenzo Forgetta, Lætitia Laurent, Zaman Afrasiabi, Meriem Bouab, Chris Tselios, Xiaoqing Xue, Marc Afilalo, Maureen Oliveira, Janick St-Cyr, Ariane Boisclair, Jiannis Ragoussis, Daniel Auld, Daniel E. Kaufmann, G. Mark Lathrop, Guillaume Bourque, Simon Décary, Emilia Liana Falcone, Alexandre Montpetit, Alain Piché, Christel Renoux, Natàlia Blay, Sze Man Tse, Ma’n H. Zawati, Lea K. Davis, Nancy J. Cox, Jennifer E. Below, Julia Sealock, Annika Faucon, Megan M. Shuey, Hannah G. Polikowsky, Lauren E. Petty, Douglas M. Shaw, Hung‐Hsin Chen, Wanying Zhu, Axel Schmidt, Kerstin U. Ludwig, Carlo Maj, Selina Rolker, Daniella Balla, Pari Behzad, Markus M. Nöthen, Julia Fazaal, Verena Keitel, Verena Keitel, Björn‐Erik Ole Jensen, Torsten Feldt, Nikolaus Marx, Michael Dreher, Isabell Pink, Markus Cornberg, Thomas Illig, Clara Lehmann, Philipp Schommers, Jan Rybniker, Max Augustin, Lisa Knopp, Ingo Kurth, Thomas Eggermann, Sonja Volland, Marc Moritz Berger, Thorsten Brenner, Anke Hinney, Oliver Witzke, Margarethe Konik, Robert Bals, Christian Herr, Nicole Ludwig, Jörn Walter, Eicke Latz, Susanne V. Schmidt, Jennifer D. Brooks, Shelley B. Bull, Lloyd T. Elliott, France Gagnon, Celia M.T. Greenwood, Rayjean J. Hung, Jerry Lawless, Andrew D. Paterson, Lei Sun, Michael J. Rauh, Laurent Briollais, Anne‐Claude Gingras, Yvonne Bombard, Trevor J. Pugh, Jared T. Simpson, Lee Goneau, Anat R. Halevy, David M. Maslove, Bjug Borgundvaag, Luke Devine, Erin Bearss, David Richardson, Saranya Arnoldo, Steven Friedman, Ahmed Taher, Seth Stern, Marc Dagher, Jovanka Vasilevska‐Ristovska, Catherine M. Biggs, Beata Mickiewicz, Lisa J. Strug, Stephen W. Scherer, Naveed Aziz, Steven J.M. Jones, Bartha Maria Knoppers, Mark Lathrop, Stuart E. Turvey, Rae S. M. Yeung, Upton Allen, Angela M. Cheung, Margaret S. Herridge, Miranda Hunt, Jordan Lerner‐Ellis, Jennifer Taher, Rulan S. Parekh, Linda T. Hiraki, Juthaporn Cowan, Francine M. Ducharme, Mario Ostrowski, François P. Bernier, Jim Kellner, Elika Garg, Samantha Yoo, Caitlyn Vlasschaert, Erika Frangione, Monica Chung, Abdul Noor, Elena Greenfeld, Karen Colwill, Marc Clausen, Gary Chao, FengYun Yue, Marvin J. Fritzler, Joseph Whitney, Bhooma Thiruvahindrapuram, Jean‐Michel Garant, Rohan Abraham, Adrienne D. Davis, Aaron Campigotto,

Investigating the role of host genetic factors in COVID-19 severity and susceptibility can inform our understanding of the underlying biological mechanisms that influence adverse outcomes and drug development 1,2 .Here we present a second updated genome-wide association study (GWAS) on COVID-19 severity and infection susceptibility to SARS-CoV-2 from the COVID-19 Host Genetic Initiative (data release 7).We performed a meta-analysis of up to 219,692 cases and over 3 million controls, identifying 51 ...

Nature Portfolio

Fabienne Charbit‐Henrion, Manon Haas, Stanislas Chaussade, Christophe Cellier, Nadine Cerf–Bensussan, Georgia Malamut, Shérine Khater, Anis Khiat, Sascha Cording, Marianna Parlato, Marie‐Agnès Dragon‐Durey, F. Beuvon, Nicole Brousse, Benoît Terris, Capucine Pïcard, Mathieu Fusaro, Frédéric Rieux‐Laucat, Marie‐Claude Stolzenberg, Anne‐Sophie Jannot, Alexis Mathian, Matthieu Allez, Marion Malphettes, Claire Fieschi, Alexandre Aubourg, Camille Zallot, Xavier Roblin, Véred Abitbol, Arthur Belle, Pauline Wils, Morgane Cheminant, Tamara Matysiak‐Budnik, Lucine Vuitton, Philippe Pouderoux, Laurent Abramowitz, Martin Castelle, Félipe Suarez, Olivier Hermine, Frank M. Ruemmele, Luc Mouthon,

Autoimmune enteropathy (AIE) is a severe form of enteropathy characterized by chronic diarrhea refractory to any exclusion diet and associated with autoimmunity.1Schiepatti A. et al.Gut. 2022 Jun 8; (gutjnl-2021-326645)PubMed Google Scholar,2Villanacci V. et al.Clin Immunol. 2019; 207: 10-17Crossref PubMed Scopus (14) Google Scholar Despite this clear definition, diagnosis is challenging. The presence of antienterocyte antibodies against the AIE-75kDa antigen3Kobayashi I. et al.Gastroenterology. 1999; ...

Tópico(s): Genetic factors in colorectal cancer

2022 - Elsevier BV | Clinical Gastroenterology and Hepatology

Jennifer A. Jackson, Amy S. Kennedy, Michael J. Moore, Artur Andriolo, Connor C. G. Bamford, Susannah Calderan, Ted Cheeseman, George Gittins, Kátia R. Groch, Natalie Kelly, Russell Leaper, MS Leslie, S Lurcock, Brian Miller, J. D. Richardson, Victoria J. Rowntree, Patrick Smith, Emilie Nicoline Stepien, Gabriele Stowasser, Philip N. Trathan, Els Vermeulen, Alexandre N. Zerbini, Emma L. Carroll,

... killed in the sub-Antarctic waters off South Georgia (South Atlantic) between 1904 and 1965. In recent ... from a summertime vessel-based expedition to South Georgia, stable isotope data collected from SRWs and putative prey and sightings reports collated by the South Georgia Museum. The expedition used directional acoustics and visual ... The isotopic position of SRWs in the South Georgia food web suggests feeding on a combination of ... and an increasing humpback whale presence in South Georgia waters following the cessation of whaling.

Tópico(s): Marine and fisheries research

2020 - Inter-Research | Endangered Species Research

Janaína Gomes‐da‐Silva, Fabiana Ranzato Filardi, Maria Regina de Vasconcellos Barbosa, José Fernando A. Baumgratz, Carlos Eduardo de Mattos Bicudo, Taciana Barbosa Cavalcanti, Marcus A. Nadruz Coelho, Andréa Ferreira da Costa, Denise Pinheiro da Costa, Eduardo Dalcin, Paulo H. Labiak, Haroldo Cavalcante de Lima, Lúcia G. Lohmann, Leonor Costa Maia, Vidal de Freitas Mansano, Mariângela Menezes, Marli Pires Morim, Carlos Wallace do Nascimento Moura, Eimear Nic Lughadha, Denílson Fernandes Peralta, Jefferson Prado, Nádia Roque, João Renato Stehmann, Lana da Silva Sylvestre, Larissa Trierveiler‐Pereira, Bruno Machado Teles Walter, Geraldo Zimbrão, Rafaela Campostrini Forzza, Fernanda Pessi de Abreu, Maria Carolina de Abreu, Vanessa Holanda Righetti de Abreu, Rafael Acuña Castillo, Edgar Augusto Lobato Afonso, Leandro de Almeida Neves Nepomuceno Agra, María F. Agra, Daniel P. P. de Aguiar, Elisa Teixeira Aires, Frank Almeda, Gracineide S.S. Almeida, Mariana M. Almeida, Nicolli Bruna Cabello de Almeida, Rafael Felipe de Almeida, Roberto B.P. Almeida, Thaís Elias Almeida, Eduardo Bezerra de Almeida, Daniela Alves, Flávio Macêdo Alves, Karina N.L. Alves, Maria B.B. Alves, Rodolfo F. Alves, Maria Clara Estanislau do Amaral, André L.S. Amaral, Leandro de Almeida Amélio, André M. Amorim, Bruno S. Amorim, Eduardo Toledo de Amorim, Vívian Oliveira Amorim, Ivanilza Moreira de Andrade, Ray S. Andrade, Thiago André, Regina Helena Potsch Andreata, Caroline Oliveira Andrino, María Betiana Ângulo, Cassiane Barroso dos Anjos, Guilherme Medeiros Antar, Mirian C.A. Antonicelli, Lorena Lana Camelo Antunes, Lidyanne Yuriko Saleme Aona, Marcelo D. Arana, João L.M. Aranha, Anderson G.A. Araújo, Andréa Onofre de Araújo, Camila C. Araújo, Cíntia Aparecida Teixeira Araújo, Filipe Maia Araújo, Mário H.T. Araújo, María Mercedes Arbo, Emily S. Arnou, Renata Asprino, Francine C. Assis, Leandro C. S. Assis, Marta Camargo de Assis, Francisco Athayde Filho, Sarah Maria Athiê‐Souza, Igor Henrique Freitas Azevedo, Lucas F. Bacci, Camilo V.O. Barbosa, Juliana Ferreira Barbosa, Rafael Gomes Barbosa‐Silva, Ian C. Barcellos, Gloria E. Barboza, Flávia Regina Baptista Barcelos, Laísa Barcelos, Kamilla L. Barreto, Fábio de Barros, Thiago Oliveira Barros, Maria Beatriz Barbosa de Barros Barreto, Cid José Passos Bastos, Cláudia Araújo Bastos, João A. N. Batista, Marcella M.I. Batista, Hortensia Pousada Bautista, Adarilda Petini Benelli, Nicolas Garcia Berguecio, Luís Carlos Bernacci, Maila Beyer, Andrea Carla Caldas Bezerra, Luísa M.P.A. Bezerra, Yuri R.L. Bezerra, Luciano B. Bianchetti, Narcísio C. Bigio, Leonardo Biral, VINICIUS FERRACINI BISSOLI, Felipe Bittencourt, Thuane Bochorny, Amabily Bohn, Lynn Bohs, Gabriel F.P. Bojacá, Abril Boldorini, Ilsi Iob Boldrini, Mônica Bolson, Juçara Bordin, Natali G. Bordon, Rafael Augusto Xavier Borges, Rodrigo L. Borges, Roseli Lopes da Costa Bortoluzzi, Claudia Petean Bove, Massimo G. Bovini, João Marcelo Alvarenga Braga, Nayara S.S. Braga, Suema Branco, Laiana M. Brauner, Denise Monte Braz, João B. A. Bringel, A. L. V. Toscano de Brito, Eliete S. Brito, Carla Poleselli Bruniera, Mônica Gomes Buchoski, William R. Buck, Norma Catarina Bueno, VINÍCIUS R. BUENO, Henrique Mallmann Büneker, Mariana de Oliveira Bünger, Maria T.A. Buril-Vital, George P. Burton, Andressa Cabral, Elsa L. Cabral, Fernanda Nunes Cabral, Tiara Sousa Cabral, Mayara K. Caddah, Claudenir Simões Caires, Taiara Aguiar Caires, Luana Silva Braucks Calazans, Diana Kelly Dias Caldas, Maria Fernanda Calió, Joel Calvo, Paulo Eduardo Aguiar Saraiva Câmara, Rodrigo Augusto Camargo, MEL C. CAMELO, Antônio Campos-Rocha, Elisa Candido, Bianca Kalinowski Canestraro, Thais S. Canto‐Dorow, Patrick de Castro Cantuária, Álison L. Cara, Gonzalo Cárdenas, Anabela Cardoso, Domingos Cardoso, J. Cardoso, Leandro Jorge Telles Cardoso, Pedro Henrique Cardoso, Andrey Lucas Cardozo, Nállarett M.D. Cardozo, Dimas Marchi do Carmo, João Afonso Martins do Carmo, Camila R. Carneiro, Cláudia Elena Carneiro, Tatiana Tavares Carrijo, Maria Beatriz Rossi Caruzo, Catarina Silva de Carvalho, Dariane A.S. Carvalho, Fernanda Antunes Carvalho, Maria Luiza Silveira de Carvalho, Jefferson Carvalho-Sobrinho, Micheline Carvalho‐Silva, Ana Carolina Devides Castello, Márcia S. Castro, I.C. Silva, Fernanda S. Catenacci, L. H. Cavalcanti, Larissa Cavalheiro, Armando Carlos Cervi, Roberta Gomes Chacon, Aline Pitol Chagas, Earl C.O. Chagas, Alain Chautems, Olivier Chauveau, Renata Nicora Chequín, Anderson Luiz Christ, Jheniffer A. Christ, Bruno B. Cidrão, Lynn G. Clark, Alexa A.O.P. Coelho, Guilherme Peres Coelho, Rubens Luiz Gayoso Coelho, Gabriel Dalla Colletta, Matheus Colli‐Silva, Adilva de Souza Conceição, Tulio C. Conceição, João Paulo S. Condack, Fernanda L. Contro, Inês Cordeiro, Luciana Silva Cordeiro, Wesley Cordeiro, Ana L.A. Côrtes, Daniel Costa, Fabiane Nepomuceno Costa, Fernanda S.N. Costa, Francisco C.P. Costa, Géssica A.G. Costa, Isabelle Gomes Cardoso Machado da Costa, Itayguara Ribeiro da Costa, Jeferson Miranda Costa, Jorge Antônio Silva Costa, José G.S. Costa, Maria T.R. Costa, Mitchel I.A. Costa, Suzana Maria Costa, Thiago Vieira Costa, Tiago Souza Costa, Maria B. Costa e Silva, James Lucas da Costa‐Lima, Matheus Martins Teixeira Cota, Yuri S. V. Couceiro, Thales Silva Coutinho, Dayvid Rodrigues Couto, Ricardo S. Couto, Anielly F. Couvo, Stephany B. Cyrillo, Luis H. Dal Molin, Cleiton Dalastra, Rafaella Georgia Lima Damasceno, Lara R.P. De Lazzari, Leonardo Paz Deble, Carolina Delfini, G. Delgado, Alfonso Delgado‐Salinas, Aline Possamai Della, Piero G. Delprete, Massimiliano Dematteis, Greta Aline Dettke, Marcelo Fernando Devecchi, Talita S. Dewes, Fernando R. Di Maio, Kauê N.L. Dias, Micheli C. Dias, Pedro Henrique dos Santos Dias, Yani Aranguren, Vinícius A.O. Dittrich, Yoannis Domínguez, Marcos da Costa Dórea, Mariane P. Dorneles, Stefan Dreßler, Marília Cristina Duarte, Juan David Tovar, Julie Henriette Antoinette Dutilh, Leo X.C. Dutra, Valquíria Ferreira Dutra, Lívia Echternacht, Lilian Eggers, Roy H.J. Erkens, Marcelo P. Eslabão, Fábio S. Espírito Santo, Hans‐Joachim Esser, Liliana Essi, Gerleni Lopes Esteves, Roberto Lourenço Esteves, Joel F. Everling, Cecilia Ezcurra, Marlon Garlet Facco, Andrea A. Cabaña Fader, Marcus J.A. Falcão, Laura Bubantz Fantecelle, Gabriela E. Farco, Allan Laid Alkimim Faria, Ana P.G. Faria, Aparecida Donisete de Faria, Maria Tereza de Marsillac Pasinato, Jair Eustáquio Quintino Faria, Simone Farias, Rosana Farias‐Singer, Maria Ana Farinaccio, Ana Clara Gonçalves Fernandes, Fernando Fernandes de Oliveira Neto, José Manuel Fernandes, Rozijane Santos Fernandes,

Abstract The shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous ...

Wiley

Erola Pairo‐Castineira, Konrad Rawlik, Andrew D. Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A. McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S. Thwaites, Kirstie Morrice, Seán Keating, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Julian C. Knight, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Colin B. Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A. Riancho, Augusto Rojas‐Martínez, Pablo Lapunzina, Sara Clohisey, Johnny Millar, Manu Shankar‐Hari, Emma Aitkin, Latha Aravindan, Ruth Armstrong, J. Kenneth Baillie, Heather Biggs, Ceilia Boz, Adam Brown, Primmy Chikowore, Richard Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Naomi Kearns, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Christen Lauder, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Sheena Murphy, Hellen Mybaya, Miranda Odam, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Petra Tucker, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Jacqueline Pan, Neus Grau, Tim Jones, Rosario Lim, Martina Marotti, R. Chris Whitton, Aneta Bociek, Sara Campos, Gill Arbane, Manu Shankar‐Hari, Marlies Ostermann, Mina Cha, Fabiola DAmato, Eirini Kosifidou, Shelley Lorah, Kyma Morera, Sarah Bircham, Laura Brady, Keith Hugill, Jeremy Henning, Stephen Bonner, Evie Headlam, Jessica Jones, A. List, J Morley, Amy Welford, Bobette Kamangu, Anitha Ratnakumar, Abiola Shoremekun, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew L. Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, P. May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, Olivier Zongo, S. M. Wood, Anne Zak, David Collier, Manuela Mundy, C. C. Thompson, Lisa Pritchard, Minnie Gellamucho, David Cartlidge, Nageswar Bandla, Lucy Bailey, Michelle Davies, Jane Delaney, Leanne Scott, Marwa Abdelrazik, Frater Alasdair, David Carter, Munzir Elhassan, Arunkumar Ganesan, Samuel Jenkins, Zoe Lamond, Dharam Purohit, Kumar Rohit, Malik Saleem, Alanna Wall, Kugan Xavier, Dhanalaksmi Bakthavatsalam, Kirolos Gehad, Pakeerathan Gnanapragasam, Kapil Jain, Swati Jain, Abdul Malik, Naveen Pappachan, Jerónimo Moreno-Cuesta, Anne Haldeos, Rachel Vincent, Maryjane Oziegb, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Abigail Knighton, Monalisa Nayak, Evita Pappa, Rohit Saha, Sian Saha, Andrew Dodd, Kevin O’Reilly, Mark McPhail, Emma Clarey, Harriet Noble, John Smith, Phoebe Coghlan, Stephen J. Brett, Anthony Gordon, Maie Templeton, David Antcliffe, Dorota Banach, Sarah Darnell, Ziortza Fernandez, Eleanor Jepson, Amal Mohammed, Roceld Rojo, Sonia Sousa Arias, Anita Gurung, Jenny Wong, Jaime Fernandez-Roman, David Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, Alicia Waite, Karen Williams, Victoria Waugh, Ingeborg Welters, Jessica Emblem, Maria Norris, David Shaw, Archana Bashyal, Sally Beer, Paula Hutton, Stuart McKechnie, Neil Davidson, Soya Mathew, Grace Readion, Jung Hee Ryu, Jean Wilson, Shruti Agrawal, Kay Elston, Megan Jones, Eoghan Meaney, Petra Polgarova, Muhammad Elbehery, Charlotte Summers, Esther Daubney, Anthony Ng, Jocelyn R. Marshall, Nazima Pathan, Katerina Stroud, Deborah White, Angela Andrew, Saima Ashraf, Amy Clark, Martin Dent, Margaret Langley, Cecilia Peters, Lucy Ryan, Julia Sampson, Shuying Wei, Alice Baddeley, Megan Meredith, Lucy Morris, Alexandra Gibbons, Lisa McLoughlin, Carlos Castro Delgado, Victoria Clark, Deborah Dawson, Lijun Ding, Georgia Durrant, Obiageri Ezeobu, Abiola Harrison, William James Hurt, Rebecca Kanu, Ashley Kinch, Susannah Leaver, Ana Lisboa, Jisha Mathew, Kamal Patel, Romina Pepermans Saluzzio, John Rawlins,

Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown

Nature Portfolio

Mari Niemi, Juha Karjalainen, Rachel G. Liao, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Shea J. Andrews, Masahiro Kanai, Kumar Veerapen, Israel Fernández‐Cadenas, Eva C. Schulte, Pasquale Striano, M. Marttila, Camelia C. Minică, Eirini Marouli, Mohd Anisul Karim, Frank R. Wendt, Jeanne E. Savage, Laura Sloofman, Guillaume Butler‐Laporte, Han‐Na Kim, Stavroula Kanoni, Yukinori Okada, Jinyoung Byun, Younghun Han, Mohammed Jashim Uddin, George Davey Smith, Cristen J. Willer, Joseph D. Buxbaum, Juha Mehtonen, Hilary K. Finucane, Mattia Cordioli, Alicia R. Martin, Wei Zhou, Bogdan Paşaniuc, Hanna Julienne, Hugues Aschard, Huwenbo Shi, Loïc Yengo, Renato Polimanti, Maya Ghoussaini, Jeremy Schwartzentruber, Ian Dunham, Karolina Chwiałkowska, Margherita Francescatto, Amy Trankiem, Mary K. Balaconis, Lea K. Davis, Sulggi A. Lee, James R. Priest, Alessandra Renieri, Vijay G. Sankaran, David A. van Heel, Patrick Deelen, J. Brent Richards, Tomoko Nakanishi, Les Biesecker, V. Eric Kerchberger, J. Kenneth Baillie, Francesca Mari, Anna Bernasconi, J. Kenneth Baillie, Arif Canakoglu, Brooke N. Wolford, Annika Faucon, Atanu Kumar Dutta, Claudia Schurmann, Emi N. Harry, Ewan Birney, Huy Nguyen, Jamal Nasir, Mari Kaunisto, Matthew Solomonson, Nicole Dueker, Nirmal Vadgama, Sophie Limou, Souad Rahmouni, Hamdi Mbarek, Dima Darwish, Md Mesbah Uddin, Raquel Albertos, Jordi Pèrez‐Tur, Ruolin Li, Lasse Folkersen, Ida Moltke, Nils Koelling, Alexander Teumer, Athanasios Kousathanas, Alicia Utrilla, Ricardo A. Verdugo, Ruth Zárate, Carolina Medina‐Gómez, David Gómez-Cabrero, Elena Carnero‐Montoro, Carmen L. Cadilla, Andrés Moreno‐Estrada, Adriana Garmendia, Leire Moya, Bahareh Sedaghati-khayat, Palwendé Romuald Boua, Marie-Julie Favé, Laurent C. Francioli, Audrey Lemaçon, Isabelle Migeotte, Sanjay Patel, Réka Várnai, József Szentpéteri, Csilla Sipeky, Francesca Colombo, Kathrin von Hohenstaufen, Píetro Lió, Costanza L. Vallerga, Qingbo Wang, Yosuke Tanigawa, Hogune Im, Chulho Han, Han Song, Jiwoo Lim, Y.‐A. Lee, Sugyeong Kim, Sangyoon Im, Biljana Atanasovska, Hajar Fauzan Ahmad, Cindy G. Boer, Philip R. Jansen, Lude Franke, Elżbieta Kaja, Dorota Pasko, Ingrid Kennis-Szilagyi, Sergey A. Kornilov, Vid Prijatelj, Ivana Nedeljković, Ilangkumaran Sivanadhan, Sarala Perumal, Sahar Esmaeeli, Nathaniel M. Pearson, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Jorge Esparza-Gordillo, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Catherine H. Weldon, Minoli A. Perera, Kevin J. O’Leary, Matthew Tuck, Travis J. O’Brien, David Meltzer, Peter H. O’Donnell, Edith A. Nutescu, Guang Yang, Cristina Alarcón, Stefanie Herrmann, Sophia Mazurek, Jeff Banagan, Zacharia Hamidi, April Barbour, Noora Raffat, Diana Moreno, Paula N. Friedman, Bart Ferwerda, Diederik van de Beek, Matthijs C. Brouwer, Alexander P. J. Vlaar, W. Joost Wiersinga, Daniëlle Posthuma, Elleke Tissink, A. H. Koos Zwinderman, Emil Uffelmann, Michiel A. van Agtmael, Anne Geke Algera, Frank van Baarle, Diane Bax, Martijn Beudel, Harm Jan Bogaard, Marije K. Bomers, Peter I. Bonta, Lieuwe D. J. Bos, Michela Botta, Justin de Brabander, Godelieve de Bree, Sanne de Bruin, Marianna Bugiani, Esther Bulle, Osoul Chouchane, Alex Cloherty, Dave A. Dongelmans, Paul Elbers, Lucas M. Fleuren, Suzanne E. Geerlings, Bart F. Geerts, Teunis B. H. Geijtenbeek, Armand R. J. Girbes, Abraham Goorhuis, Martin P. Grobusch, Florianne Hafkamp, Laura A. Hagens, Jörg Hamann, Vanessa Harris, Robert Hemke, Sabine Hermans, Leo Heunks, Markus W. Hollmann, Janneke Horn, Joppe W. Hovius, Menno D. de Jong, Rutger Koning, Niels van Mourik, Jeannine F. Nellen, Esther J. Nossent, Frederique Paulus, Edgar Peters, Tom van der Poll, Bennedikt Preckel, Jan M. Prins, Jorinde Raasveld, Tom D. Y. Reijnders, Michiel Schinkel, Marcus J. Schultz, Alex R. Schuurman, Kim Sigaloff, Marry R. Smit, Cornelis Stijnis, Willemke Stilma, Charlotte E. Teunissen, Patrick Thoral, Anissa M. Tsonas, Marc van der Valk, Denise P. Veelo, Heder de Vries, Michèle van Vugt, Dorien Wouters, René Minnaar, Adrie Kromhout, Kees W. J. van Uffelen, Ruud A. Wolterman, Genevieve Roberts, Daniel J. Park, Catherine A. Ball, Marie V. Coignet, Shannon McCurdy, Spencer C. Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Miloš Pavlović, Eurie L. Hong, Kristin A. Rand, Ahna R. Girshick, Harendra Guturu, Asher Haug Baltzell, Souad Rahmouni, Julien Guntz, Y Beguin, Sara Pigazzini, Lindokuhle Nkambule, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Julien Guiot, Laurent Jadot, Samira Azarzar, Patricia Dellot, Stéphanie Gofflot, Sabine Claassen, Axelle Bertrand, Gilles Parzibut, Mathilde Clarinval, Catherine Moermans, Olivier Malaise, Kamilia El Kandoussi, Raphaël Thonon, Pascale Huynen, Alyssia Mesdagh, Sofia Ferreira Melo, Nicolas Jacques, Emmanuel Di Valentin, François Giroule,

The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-19

Nature Portfolio

I Dajti, José Ignacio Valenzuela, L Boccalatte, Nicolas A Gemelli, Dantwan Smith, Nagendra N. Dudi‐Venkata, Hidde M. Kroon, Tarik Sammour, Matthew M. Roberts, D Mitchell, K Lah, A Pearce, Dion Morton, Amanda Dawson, A Drane, Claire Sharpin, Ramesh Nataraja, Maurizio Pacilli, Daniel Cox, Vijayaragavan Muralidharan, Georgina Riddiough, Edmund Clarke, Wael Jamel, Kirby R. Qin, Peter Pockney, Daron Cope, N Egoroff, Natalie Lott, Sven Putnis, S De Robles, Zen Yang Ang, Martin Mitteregger, Stefan Uranitsch, Marjorie Stiegler, Gerald Seitinger, Felix Aigner, D B Lumenta, Sebastian P. Nischwitz, Erika Richtig, Mauro Pau, Petra Srekl-Filzmaier, Nicolas Eibinger, Birgit Michelitsch, Melanie Fediuk, A Papinutti, Geoffrey Seidel, Joseph Kahn, Tina Cohnert, Donna A. Messner, F. Ofner, J Presl, Márta Varga, Michael Weitzendorfer, K. Emmanuel, Alf-Dorian Binder, Marc Zimmermann, S Holawe, Emeka Nkenke, Christoph Grimm, M Kranawetter, Ashrarur Rahman Mitul, Nazmul Islam, Syed S. Karim, Niels Komen, Sven Putnis, S De Robles, Emily Ang, Herbert De Praetere, Tim Tollens, G Schols, C. Smets, Laura Haenen, Jorien Quintens, K Van Belle, Gabriëlle H. van Ramshorst, Piet Pattyn, Liesbeth Desender, Thomas Martens, Dirk Van de Putte, Philip Lerut, Aude Grimonprez, Marcus L.F. Janssen, G. De Smul, P. Wallaert, Jef Van den Eynde, Wouter Oosterlinck, Raf Van den Eynde, An Sermon, A. Boeckxstaens, Anne-Laure Cordonnier, Jeroen De Coster, Joris Jaekers, Constantinus Politis, Marc Miserez, Nicolas Duchateau, Charles de Gheldere, Nicolas Flamey, Piet Pattyn, A Christiano, Benedetta Guidi, A L Minussi, Sílvia Castro, Willy Okoba, F H R Maldonado, Paulo Oliveira, Tiago Antônio Baldasso, Luciano Marques dos Santos, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Laércio Pol Fachin, Tainá Santos Bezerra, Aldo Vieira Barros, A Silva, A L S Leite, Daniela Silvestre, C Carvalho Ferro, M S Araujo, L. M. Lopes, P D Damasceno, D H S Araujo, Gustavo Andreazza Laporte, M Salem, Marco Guimarães-Filho, Lucas Souto Nacif, Ronald Luiz Gomes Flumignan, Luís CU Nakano, Danielle Akemi Bergara Kuramoto, A L S Aidar, Mariana Raffo Pereda, R M Correia, Brena Costa Santos, Alzira Alves de Siqueira Carvalho, Jorge Eduardo de Amorim, Henrique Jorge Guedes Neto, Libnah Leal Areias, Álvaro Francisco Lopes de Sousa, Carolina Dutra Queiroz Flumignan, W G Lustre, Doris Hupfeld Moreno, Nathana Prado de Almeida Barros, José Carlos Costa Baptista‐Silva, Leandro Luongo de Matos, L P Kowaski, Marco Aurélio Vamondes Kulcsar, KS Nunes, Marcos F.S. Teixeira, Rafael Leite Nunes, Takeshi Ijichi, N. J. Kim, Ana Beatriz Pontes Marreiro, Bárbara Müller, Joseph Awada, Glauco Baiocchi, Luiz Paulo Kowalski, JG Vartanian, Fabiana B. Makdissi, Samuel Aguiar, Nuno Marques, Genival Barbosa de Carvalho, Tatiana Marques, Emne Ali Abdallah, Charles Edouard Zurstrassen, Jamie Gross, Stênio de Cássio Zéqui, Bruna Tirapelli Gonçalves, Sigrid de Sousa dos Santos, João Pedreira Duprat Neto, Felipe José Fernández Coimbra, Rafael De Cicco, Flávio Roberto Takeda, Ivan Cecconello, Ulysses Ribeiro, A Gatti, R Oliva, C Nardi, Mihail Slavchev, Boyko Atanasov, Nikolay Belev, Angela Dell, David L. Bigam, Khaled Dajani, S Al Riyami, Janet Martin, Davy Cheng, Hua Yang, A Fayad, François Martin Carrier, E. Amzallag, Joannie Desroches, Marie T. Ruel, Natasha Caminsky, Marylise Boutros, J Moon, E. G. C. Wong, Tsafrir Vanounou, Jonathan Pelletier, S Wong, Elie Girsowicz, J Bayne, Daniel I. Obrand, Heather L. Gill, Oren K. Steinmetz, Kenneth MacKenzie, Marie‐Amélie Lukaszewski, Ghader Jamjoum, Philippe Richebé, Olivier Verdonck, S Discepola, Nathalie Godin, M. Idrissi, Vincent Lecluyse, Geneviève Côté, Sebastian Demyttenaere, Richard Garfinkle, Marylise Boutros, A Kouyoumdjian, Marylise Boutros, Sinziana Dumitra, J Moon, E. G. C. Wong, Kosar Khwaja, Lan Luo, Marie‐Amélie Lukaszewski, Heather L. Gill, Gerald J. Berry, Adrienne Liberman, Elie Girsowicz, J Bayne, Daniel I. Obrand, Oren K. Steinmetz, Kenneth MacKenzie, Severin Schmid, Jonathan Spicer, Mehdi Farsi, Jad Abou‐Khalil, Étienne J. Couture, Seyede Momeneh Mohammadi, Hugo Tremblay, Nathalie Gagné, Anne Bergeron, Alexis F. Turgeon, O. Costerousse, David Bellemare, C. Babin, Catherine Blier, M L Wood, Amit Persad, Gary Groot, Hau Pham, Frédérick D’Aragon, Élaine Carbonneau, Maude Bouchard, Marie-Hélène Masse, F Pesant, Jennifer Héroux, Paul J. Karanicolas, Julie Hallet, A Nadler, Avery B. Nathens, M Ko, A Brar, Kelly Mayson, B Kidane, Sadeesh Srinathan, M Escudero, Janette T. Reyes, María Marta Modolo, P Ramirez Nieto, Rodrígo Sepúlveda, A Bolbarán, Andrés Molero‐Chamizo, Isaac Ruiz, Gabriel Reyes, Rafael Salas, Cristóbal Suazo, Rodrigo Muñoz, E Grasset, Martín Inzunza, Nicolás Besser, M J Irarrázaval, Cristián Jarry, Felipe Bellolio, C A Romero Manqui, M Ruiz Esquide, T. Fuentes, José Luis Campos, C. Perez, Payton Cabrera, Raúl Eduardo Pinilla Morales, Óscar Guevara, LJ Jimenez Ramirez, B G Velasquez Cuasquen, Damián Mora, A Bonilla, Sandra Diaz, E Manrique,

To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide ...

Oxford University Press

John L. Gittleman,

... Drouet-Hoguet, Sandrine Ruette, Sébastien Devillard, Michel Albaret, Alexandre Millon Rural populations of the red fox Vulpes ... 10.1111/j.1365-2656.2009.01616.xJosé Alexandre Felizola Diniz-Filho, Miguel Ãngel Rodríguez, Luis Mauricio ... 1420-9101.2003.00664.xNatália Mundim Tôrres, José Alexandre Felizola Diniz-Filho, , Phylogenetic autocorrelation and evolutionary diversity ...

Tópico(s): Species Distribution and Climate Change

1986 - University of Chicago Press | The American Naturalist

Eli Geffen, Matthew E. Gompper, John L. Gittleman, Hang‐Kwang Luh, David W. Macdonald, Robert K. Wayne,

... 0300-3256.2004.00152.xNatália M. Tôrres, José Alexandre F. Diniz-Filho, Macroecologia de carnívoros do Novo ... 115–144.https://doi.org/10.1007/BF03192423José Alexandre Felizola Diniz-Filho PHYLOGENETIC AUTOCORRELATION UNDER DISTINCT EVOLUTIONARY ... 10.1111/j.0014-3820.2001.tb00630.xJosé Alexandre Felizola Diniz-Filho PHYLOGENETIC AUTOCORRELATION UNDER DISTINCT EVOLUTIONARY ... 657.https://doi.org/10.1590/S0034-71081998000400012José Alexandre Felizola Diniz-Filho, Carlos Eduardo Ramos de Sant' ...

Tópico(s): Ecology and biodiversity studies

1996 - University of Chicago Press | The American Naturalist

Celso Pontes,

... Antonio Federico; Latvia – Prof. Gertrude Enina; Luxemburg – Dr Alexandre Bisdorff; – The Netherlands – Prof. J. Troost – Norway – Prof. ... Kesseelring; Turkey – Prof. Rana Karabudak, Prof. Tulay Kansu; Georgia – Prof. Janelidze Marina. E.F.N.S. Task ...

Tópico(s): Clinical Reasoning and Diagnostic Skills

2001 - Wiley | European Journal of Neurology

Tom Abbott, T. Ahmad, M.K. Phull, A.J. Fowler, Russ Hewson, Bruce Biccard, Michelle S. Chew, Michael Gillies, Rupert M. Pearse, Rupert M. Pearse, Scott Beattie, Pierre-Alain Clavien, Nicolas Demartines, Lee A. Fleisher, Michael P. W. Grocott, J. B. Haddow, Andrea Bianchin, Peter Holt, Rui P. Moreno, Naomi Pritchard, Andrew Rhodes, Duminda N. Wijeysundera, M.G.F. Wilson, Tahania Ahmed, Kirsty Everingham, Russ Hewson, Marta Januszewska, Mandeep-Kaur Phull, Richard Halliwell, Mark Shulman, Paul S. Myles, Werner Schmid, M. Hiesmayr, Patrick Wouters, Stefan De Hert, Suzana M. Lobo, Xiangming Fang, Lars S. Rasmussen, Emmanuel Futier, Matthieu Biais, Aurélien Venara, K. Slim, Michael Sander, Despoina Koulenti, Kostoula Arvaniti, Matthew T.V. Chan, Atul Kulkarni, Susilo Chandra, Aida Rosita Tantri, Emad Geddoa, Muntadhar Abbas, Giorgio Della Rocca, Datin Sivasakthi, Marzida Mansor, Pastor Luna, R. Arthur Bouwman, Wolfgang Bühre, Vanessa Beavis, Doug Campbell, Timothy G. Short, Tunde Osinaike, Ricardo Matos, Ioana Grigoraş, М. Yu. Кirov, Д. Н. Проценко, Bruce Biccard, César Aldecoa, Michelle S. Chew, Christoph K. Hofer, Martin Hübner, James Ditai, Tamás Szakmány, Lee A. Fleisher, Marissa Ferguson, Michael MacMahon, Ritchie Cherian, Helen Currow, Kathirgamanathan Kanathiban, David Gillespie, Edward Pathmanathan, Katherine W. Phillips, J Reynolds, Joanne Rowley, J. Douglas, Ross Kerridge, Sameer Garg, Michael Bennett, Megha Jain, David Alcock, N Terblanche, R Cotter, Kate Leslie, Marcelle Stewart, Nicolette Zingerle, Antony Clyde, Oliver Hambidge, Adam Rehak, Sharon Cotterell, Wilson Binh Quan Huynh, Timothy M. McCulloch, Erez Ben‐Menachem, Thomas M. Egan, Jennifer R. Cope, Paul Fellinger, Markus Haisjackl, Simone Haselberger, Caroline Holaubek, Paul Lichtenegger, Florian Scherz, Franz Hoffer, Veronika Cakova, Andreas Eichwalder, Norbert Fischbach, R. Klug, Elisabeth Schneider, Martin Veselý, Reinhart Wickenhauser, Karl Gernot Grubmueller, Marion Leitgeb, Friedrich Lang, Nancy Toro, Marlene Bauer, Friedrich Laengle, Claudia Haberl, Thomas Mayrhofer, Christoph Trybus, Christian Buerkle, Karin Forstner, Reinhard Germann, Harald Rinoesl, Elke Schindler, Ernst Trampitsch, Gerhard Bogner, Daniel Dankl, Martin Duenser, G. Fritsch, Ilse Gradwohl-Matis, Andreas Hartmann, Thomas Hoelzenbein, Tarkan Jaeger, Franz Landauer, Gregor Lindl, Michael Lux, Johannes Steindl, Ottokar Stundner, Christian Szabo, Jawad Bidgoli, Hans Verdoodt, Patrice Forget, D. Ethan Kahn, Fernande Lois, Mona Momeni, Caroline Prégardien, Audrey Pospiech, Arnaud Steyaert, Laurent Veevaete, Dirk De Kegel, K. De Jongh, L. Foubert, Carine Smitz, M. Vercauteren, Jan Poelaert, Veerle Van Mossevelde, J Abeloos, Stefaan Bouchez, Marc Coppens, Luc De Baerdemaeker, Isabel Deblaere, Ann De Bruyne, Kristine Fonck, Björn Heyse, Tom Jacobs, Koen Lapage, Anneliese Moerman, Martine Neckebroek, Aliaksandra Parashchanka, Nathalie Roels, Nancy Van Den Eynde, Michaël Vandenheuvel, JurgenVan Limmen, Ann Vanluchene, Caroline Vanpeteghem, Piet Wyffels, Christel Huygens, Punitha Vandenbempt, Marc Van de Velde, Dimitri Dylst, Bruno Janssen, Evelien Schreurs, Fábia Berganton Aleixo, Keulle Candido, Hugo Dias Batista, Mário Guimarães, Jaqueline Guizeline, João Hoffmann, Francisco Ricardo Marques Lobo, Vinicius Carraro do Nascimento, Katia Nishiyama, Lucas Eduardo Pazetto, Daniela Souza, Rodrigo Rodrigues, Ana Maria Vilela dos Santos, Jaquelline Jardim, Luíz Marcelo Sá Malbouisson, João Silva, Paulo do Nascimento, Thalissa Hermínia Baio, Gabriel Isaac Pereira de Castro, Henri Roger Watanabe Oliveira, Cristina Prata Amêndola, Gutemberg Cardoso, Daniela Ortega, Ana Flavia Brotto, Mirella Cristine de Oliveira, Álvaro Réa-Neto, Fernando Augusto Lavezzo Dias, M. Travi, L. Zerman, Pedro Azambuja, Marcos Freitas Knibel, Antônio Sérgio Martins, William Almeida, Calim Neder Neto, Maria Ângela Tardelli, Eliana Bernadete Caser, Márcio Machado, Crisitiano Aguzzoli, Sérgio Vasconcellos Baldisserotto, Fernanda Beck Tabajara, Fernanda Bettega, La Hore Correa Rodrigues Júnior, Julia de Gasperi, Lais Faina, Marcos Farias Nolasco, Bruna Ferreira da Costa Fischer, Mariana Fosch de Campos Ferreira, Cristina Hartmann, Marta Kliemann, Gustavo Luis Hubert Ribeiro, Julia Merladete Fraga, Thiago Motta Netto, Laura Valduga Pozza, Paulo Rafael Wendling, Caroline Azevedo, Juliana Bueno Garcia, Marcel Rezende Lopes, Bernardo Maia, Paula Maselli, Ralph Melo, Weslley Mendes, Matheus Neves, Jacqueline Ney, Cláudio Piras, Christopher Applewhaite, Adrienne Carr, Lorraine Chow, Kaylene Duttchen, Julena Foglia, Michael W. Greene, Ashley Hinther, Kendra Houston, Thomas Jared McCormick, Jennifer Mikhayel, Sam Montasser, Alex Ragan, Andrew Suen, Adrianna Woolsey, Hai Yu, Duane J. Funk, Stephen Kowalski, Regina Legaspi, Heather McDonald, Faisal Sharaf Siddiqui, Jeremy Pridham, Bernadette Rowe, Sonia Sampson, Barton Thiessen, Geoff Zbitnew, André Bernard, Ronald B. George, Philip H. Jones, Rita Moor, Naveed Siddiqui, Alexandra Wolfer, Diem Tran, Denyse Winch, Gary Dobson, Thomas Jared McCormick, Osama Montasser, Richard Hall, Leyla Baghirzada, Gerard F. Curley, Si Dai, Gregory M. T. Hare, Esther Lee, Uma Shastri,

BackgroundThe surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool.MethodsProspective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital ...

Elsevier BV

Tom Abbott, Kathryn Greaves, A Patel, Tahania Ahmad, J. B. Haddow, Emmanuel Futier, Matthieu Biais, K. Slim, Rupert M. Pearse, Rupert M. Pearse, Scott Beattie, Pierre‐Alain Clavien, Nicolas Demartines, Lee A. Fleisher, Michael P. W. Grocott, J. B. Haddow, Andreas Hoeft, Peter Holt, Rui P. Moreno, Naomi Pritchard, Andrew Rhodes, Duminda N. Wijeysundera, M.G.F. Wilson, Tahania Ahmed, Kirsty Everingham, Russ Hewson, Marta Januszewska, Rupert M. Pearse, Mandeep-Kaur Phull, Richard Halliwell, Mark Shulman, Paul S. Myles, Werner Schmid, M. Hiesmayr, Patrick Wouters, Stefan De Hert, Suzana M. Lobo, Scott Beattie, Duminda N. Wijeysundera, Xiangming Fang, Lars S. Rasmussen, Emmanuel Futier, Matthieu Biais, Aurélien Venara, K. Slim, Michael Sander, Despoina Koulenti, Kostoula Arvaniti, Matthew T.V. Chan, Atul P Kulkarni, Susilo Chandra, Aida Rosita Tantri, Emad Geddoa, Muntadhar Abbas, Giorgio Della Rocca, Datin Sivasakthi, Marzida Mansor, Pastor Luna, R. Arthur Bouwman, Wolfgang Bühre, Vanessa Beavis, Douglas Campbell, Timothy G. Short, Tunde Osinaike, Ricardo Matos, Ioana Grigoraş, М. Yu. Кirov, Д. Н. Проценко, Bruce Biccard, César Aldecoa, Michelle S. Chew, Christoph K. Hofer, Martin Hübner, James Ditai, Tamás Szakmány, Lee A. Fleisher, Marissa Ferguson, Michael MacMahon, Mark Shulman, Ritchie Cherian, Helen Currow, Kathirgamanathan Kanathiban, David Gillespie, Edward Pathmanathan, Katherine W. Phillips, J Reynolds, Joanne Rowley, J. Douglas, Ross Kerridge, Helen Currow, Sameer Garg, Michael Bennett, Megha Jain, David Alcock, N Terblanche, R Cotter, Kate Leslie, Marcelle Stewart, Nicolette Zingerle, Antony Clyde, Oliver Hambidge, Adam Rehak, Sharon Cotterell, Wilson Binh Quan Huynh, Timothy M. McCulloch, Erez Ben‐Menachem, Thomas M. Egan, Jennifer R. Cope, Richard Halliwell, Paul Fellinger, Simone Haselberger, Caroline Holaubek, Paul Lichtenegger, Florian Scherz, Werner Schmid, Franz Hoffer, Veronika Cakova, Andreas Eichwalder, Norbert Fischbach, R. Klug, Elisabeth Schneider, Martin Veselý, Reinhart Wickenhauser, Karl Gernot Grubmueller, Marion Leitgeb, Friedrich Lang, Nancy Toro, Marlene Bauer, Friedrich Laengle, Thomas Mayrhofer, Christian Buerkle, Karin Forstner, Reinhard Germann, Harald Rinoesl, Elke Schindler, Ernst Trampitsch, G. Fritsch, Christian Szabo, Jawad Bidgoli, Hans Verdoodt, Patrice Forget, D. Ethan Kahn, Fernande Lois, Mona Momeni, Caroline Prégardien, Audrey Pospiech, Arnaud Steyaert, Laurent Veevaete, Dirk De Kegel, K. De Jongh, L. Foubert, Carine Smitz, M. Vercauteren, Jan Poelaert, Veerle Van Mossevelde, J Abeloos, Stefaan Bouchez, Marc Coppens, Luc De Baerdemaeker, Isabel Deblaere, Ann De Bruyne, Stefan De Hert, Kristine Fonck, Björn Heyse, Tom Jacobs, Koen Lapage, Anneliese Moerman, Martine Neckebroek, Aliaksandra Parashchanka, Nathalie Roels, Nancy Van Den Eynde, Michaël Vandenheuvel, Jurgen Van Limmen, Ann Vanluchene, Caroline Vanpeteghem, Patrick Wouters, Piet Wyffels, Christel Huygens, Punitha Vandenbempt, Marc Van de Velde, Dimitri Dylst, Bruno Janssen, Evelien Schreurs, Fábia Berganton Aleixo, Keulle Candido, Hugo Dias Batista, Mário Guimarães, Jaqueline Guizeline, João Hoffmann, Suzana M. Lobo, Francisco Ricardo Marques Lobo, Vinicius Carraro do Nascimento, Katia Nishiyama, Lucas Eduardo Pazetto, Daniela Souza, Rodrigo Rodrigues, Ana Maria Vilela dos Santos, Jaquelline Jardim, João Silva, Paulo do Nascimento, Thalissa Hermínia Baio, Gabriel Isaac Pereira de Castro, Henri Roger Watanabe Oliveira, Cristina Prata Amêndola, Gutemberg Cardoso, Daniela Ortega, Ana Flavia Brotto, Mirella Cristine de Oliveira, Álvaro Réa-Neto, Fernando Augusto Lavezzo Dias, Pedro Azambuja, Marcos Freitas Knibel, Antônio Sérgio Martins, William Almeida, Calim Neder Neto, Maria Ângela Tardelli, Eliana Bernadete Caser, Márcio Machado, Crisitiano Aguzzoli, Sérgio Vasconcellos Baldisserotto, Fernanda Beck Tabajara, Fernanda Bettega, La Hore Correa Rodrigues Júnior, Julia de Gasperi, Lais Faina, Marcos Farias Nolasco, Bruna Ferreira Costa Fischer, Mariana Fosch Campos Ferreira, Cristina Hartmann, Marta Kliemann, Gustavo Luis Hubert Ribeiro, Julia Merladete Fraga, Thiago Motta Netto, Laura Valduga Pozza, Paulo Rafael Wendling, Caroline Azevedo, Juliana Bueno Garcia, Marcel Rezende Lopes, Bernardo Maia, Paula Maselli, Ralph Melo, Weslley Mendes, Matheus Neves, Jacqueline Ney, Cláudio Piras, Christopher Applewhaite, Adrienne Carr, Lorraine Chow, Kaylene Duttchen, Julena Foglia, Michael W. Greene, Ashley Hinther, Kendra Houston, Thomas Jared McCormick, Jennifer Mikhayel, Sam Montasser, Alex Ragan, Andrew Suen, Adrianna Woolsey, Hai Yu, Duane J. Funk, Stephen Kowalski, Regina Legaspi, Heather McDonald, Faisal Sharaf Siddiqui, Jeremy Pridham, Bernadette Rowe, Sonia Sampson, Barton Thiessen, Geoff Zbitnew, André Bernard, Ronald B. George, Philip H. Jones, Rita Moor, Naveed Siddiqui, Alexandra Wolfer, Diem Tran, Denyse Winch, Gary Dobson, Ashley Hinther, Thomas Jared McCormick, Osama Montasser, Andrew Suen, Adrianna Woolsey, André Bernard, Ronald B. George, Richard Hall, André Bernard, Ronald B. George, Richard Hall, Christopher Applewhaite, Leyla Baghirzada, Thomas Jared McCormick, Andrew Suen, Si Dai, Gregory M. T. Hare,

The Clavien-Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien-Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational ...

Oxford University Press

James Glasbey, Tom Abbott, Adesoji Ademuyiwa, Adewale Adisa, Ehab Alameer, Sattar Alshryda, Alexis Arnaud, Brittany Bankhead-Kendall, Mohamad K. Abou Chaar, Daoud Chaudhry, Ainhoa Costas‐Chavarri, Miguel F Cunha, Justine Davies, Anant Desai, Muhammed Elhadi, Marco Fiore, J.E.F. Fitzgerald, Maria Fourtounas, Alexander J. Fowler, K Futaba, Gaetano Gallo, Dhruva Ghosh, Rohan R Gujjuri, Rebecca Hamilton, Parvez Haque, Ewen M. Harrison, Peter J. Hutchinson, Gabriella Hyman, Arda Işık, Umesh Jayarajah, Haytham M.A. Kaafarani, Bryar Kadir, Ismaïl Lawani, Hans Lederhuber, Elizabeth Li, Markus Löffler, Maria Aguilera Lorena, Harvinder Mann, Janet Martin, Dennis Mazingi, Craig D McClain, Kenneth A McLean, John G. Meara, Antonio Ramos‐De la Medina, Mengistu G Mengesha, Ana Minaya, María Marta Modolo, Rachel Moore, Dion Morton, Dmitri Nepogodiev, Faustin Ntirenganya, Francesco Pata, Rupert M. Pearse, Maria Picciochi, Thomas Pinkney, Peter Pockney, Gabriëlle H. van Ramshorst, Toby Richards, April Camilla Roslani, Sohei Satoi, Raza Sayyed, Richard Shaw, Joana F F Simoes, Neil Smart, Richard Sullivan, Malin Sund, Sudha Sundar, Stephen Tabiri, Elliott H Taylor, Mary L Venn, Dakshitha Wickramasinghe, Naomi Wright, Sebastian Bernardo Shu Yip, Aneel Bhangu, Omar Omar, Ewen M. Harrison, Aneel Bhangu, Kwabena Siaw-Acheampong, Ruth Benson, Edward Bywater, Brett E Dawson, Jonathan P Evans, Emily Heritage, Conor Jones, Sivesh K. Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew T. Knight, Samuel Lawday, Harvinder Mann, Ella J Marson, S McKay, Emily Mills, Gianluca Pellino, Abhinav Tiwari, Isobel M Trout, Richard Wilkin, Sadi A. Abukhalaf, Michel Adamina, Adesoji Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeier, Osaid Alser, Muhammad Alshaar, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany Bankhead-Kendall, Emma Barlow, David Beard, Ruth Blanco‐Colino, Amanpreet Brar, Ana Minaya‐Bravo, Kerry Breen, Chris Bretherton, Igor Lima Buarque, Josh Burke, Edward Caruana, Mohamad K. Abou Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moisés Cukier, Giana H. Davidson, Salomone Di Saverio, Thomas M Drake, John Edwards, Sameh Hany Emile, Shebani Farik, Samuel Ford, Tatiana Garmanova, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A. Griffiths, Magdalena Gruendl, Constantine Halkias, Intisar Hisham, Peter J. Hutchinson, Shelley Hwang, Michael D. Jenkinson, Pascal Jonker, Debby Keller, Angelos G. Kolias, Schelto Kruijff, Sezai Leventoğlu, Andrey Litvin, Andrew P. Loehrer, María Marta Modolo, Piotr Major, Hassan Mashbari, Symeon Metallidis, Helen Mohan, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionuţ Negoi, Milagros Niquen-Jimenez, Maricarmen Olivos, Salah Eddine Oussama Kacimi, Oumaima Outani, Marie Dione Parreno-Sacdalanm, C. Perez, Thomas Pinkney, Willemijn Y. van der Plas, Ahmad Uzair Qureshi, Dejan Radenković, Antonio Ramos‐De la Medina, Elliot John Revell, Keith Roberts, April Camilla Roslani, Martin Rutegård, Juan José Segura‐Sampedro, Irène Santos, Andrew Schache, Andreas A. Schnitzbauer, Justina O. Seyi‐Olajide, Neil Sharma, Caitlin Shaw, Sebastian Shu, Kjetil Søreide, Antonino Spinelli, Grant D. Stewart, Philip Townend, Georgios Tsoulfas, Raghavan Vidya, Dale Vimalachandran, Oliver Warren, Duane Wedderburn, NA EuroSurg, NA European Society of Coloproctology, NA Global Initiative for Children's Surgery, NA GlobalSurg, NA GlobalPaedSurg, NA ItSURG, NA PTSurg, NA SpainSurg, NA Italian Society of Colorectal Surgery, NA Association of Surgeons in Training, NA Irish Surgical Research Collaborative, NA Transatlantic Australasian Retroperitoneal Sarcoma Working, NA Italian Society of Surgical Oncology, Lesley Booth, Margaret Barker, Neil Barker, Shirley Cooke, Suzanne Doré, Nigel Horwood, Emmy Runigamugabo, Carrie Tierney Weir, Mike Bahrami-Hessari, Asad Riaz, Jaffer Shah, Mohammed Safi, Dariel Thereska, Irida Dajti, Riadh Cheddadi, Anisse Tidjane, Carlos A Quinteros, Ahmed khelfaoui, Kamel Ben Salem, Omar Riffi, Salah Eddine Oussama Kacimi, Salim Loudjedi, Tidjani Damerdji, Diana Alejandra Pantoja Pachajoa, René M. Palacios Huatuco, Fernando A. Alvarez, Alejandro Marcelo Doniquian, Roberto Ariel Abeldaño Zúñiga, Francisco Schlottmann, C. Cobos, Cecilia Gigena, Agustin Albani Forneris, Agustín Duro, Agustín García-Mansilla, Virginia Cano Busnelli, C. Poggi, Pedro Mercado, Marcos González, Agustina F Castro Lalin, Horacio F. Mayer, Rodrigo Brandariz, Pablo A. Slullitel, Rocio Boudou, Pablo Lobos, María C Uffelmann, María Laura Petersen, Emilia Luzzi, F. Lichtenberger, María Amor, Celeste S Zarratea, Tomás Alfredo Esteves, Nicolas A Gemelli, Sebastián Tirapegui, Juan Liyo, Jordán Scherñuk, Luis Alejandro Boccalatte, Rubén Balmaceda, José Luis D’addino, M. Caubet, José Alfredo Calderón Arancibia, Carina Chwat, Brian Morris, Nicolás Avellaneda, Ivana Ines Pedraza Salazar, D Eskinazi, Lara Vargas, María Emilia Muriel, Stefano Lucchini, M. Gosselink, Amelia Davis, J. Barker, Kirby R. Qin, David Proud, Daniel Cox, Su Kah Goh, David S. Liu, Dan Wu, Neil D. Merrett, Sarit Badiani, Shomik Sengupta, Anshini Jain, Christopher Steen, Enoch Wong, C Ip, Matthew Leaning, Conor McCartney, Sivakumar Gananadha, Evie Yeap, Sean Stevens,

The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system strengthening and address growing backlogs.

Elsevier BV