Ramona Elena Tulbure-Andone, Nicolae Neagu, Dan Alexandru Szabo,
Tópico(s): Education and Learning Interventions
2020 - | Health Sports & Rehabilitation Medicine
Enea Ferlizza, Alexandre Campos, Alexandru Gabriel Neagu, Aurora Cuoghi, Elisa Bellei, Emanuela Monari, Francesco Dondi, André M. Almeida, Gloria Isani,
Chronic kidney disease (CKD) is a major cause of mortality in cats, but sensitive and specific biomarkers for early prediction and monitoring of CKD are currently lacking. The present study aimed to apply proteomic techniques to map the urine proteome of the healthy cat and compare it with the proteome of cats with CKD. Urine samples were collected by cystocentesis from 23 healthy young cats and 17 cats with CKD. One-dimensional sodium-dodecyl-sulfate polyacrylamide gel electrophoresis (1D-SDS-PAGE) ...
Tópico(s): Renal Diseases and Glomerulopathies
2015 - Elsevier BV | The Veterinary Journal
Elin Åberg, Sarah Holst, Alexandru Gabriel Neagu, Sven Ove Ögren, Catharina Lavebratt,
Pregnant women with epilepsy have to balance maternal and fetal risks associated with uncontrolled seizures against the potential teratogenic effects from antiepileptic drugs (AEDs). Carbamazepine (CBZ) is among the four most commonly used AEDs for treatment of pregnant epileptic women. We previously reported that new-born children had a decreased head circumference after in utero CBZ exposure. This study investigates how prenatal exposure of CBZ influences the number of neurons in new-born and young ...
Tópico(s): Epilepsy research and treatment
2013 - Public Library of Science | PLoS ONE
Ana Daniela Pascariu, Andreea Ioana Neagu, Andrei Valentin Neagu, Alexandru Băjenaru, Cezar Betianu,
Inflammatory pseudotumor-like follicular dendritic cell sarcoma is a rare histological variant of follicular dendritic cell sarcoma involving typically the spleen and the liver, often linked to the presence of Epstein-Barr virus infection. Definite diagnosis of this type of sarcoma is difficult to make owing to nonspecific clinical and imaging findings and is based on histopathological features. Inflammatory pseudotumor-like follicular dendritic cell sarcoma is described as a low-aggressivity tumor ...
Tópico(s): Vascular Tumors and Angiosarcomas
2021 - BioMed Central | Journal of Medical Case Reports
Violeta Stefania Rotărescu, Diana Bianca Matei, Ioana Alexandra Mircea, Andreea Maria Mirescu, Bogdan George Nedelescu, Daniela Georgiana Nedelea, Alexandra Neagu, Alexandru George Necșulescu, Gabriel Angelo Oteșanu, Lucian Constantin Tudor,
In the unique context of the coronavirus disease 2019 (COVID-19) pandemic, researchers and clinicians alike drew attention to the risks involved by physical and social isolation for mental health. Factors like resilience, gender, urban/rural environment, or preexisting anxiety can impact anxious states produced by home forced isolation. Based on these, we assumed that: i) there are significant differences in the level of anxiety (state) during the pandemic, depending on the living area of the subjects; ...
Tópico(s): Psychological Well-being and Life Satisfaction
2021 - PAGEPress (Italy) | Research in Psychotherapy Psychopathology Process and Outcome
Ioana Anca Ștefanopol, Liliana Baroiu, Anca-Iulia Neagu, Dumitru Marius Dănilă, Alexandru Nechifor, Magdalena Miulescu, Gabriela Bălan, Claudiu Ionuț Vasile, Elena Niculeț, Alin Laurenţiu Tatu,
Paraovarian cysts (POCs) develop within the broad ligament of the uterus. POCs are considered to be giant when the threshold of 150 mm is exceeded. Clinical signs and symptoms occur as a consequence of the pressure effect on adjacent organs or due to complications. Abdominal ultrasonography, computed tomography or magnetic resonance imaging are useful imaging tools, but most often the exact origin of such voluminous cysts is revealed only by surgical exploration. The review aims to appraise and update ...
Tópico(s): Ovarian function and disorders
2022 - Dove Medical Press | Therapeutics and Clinical Risk Management
Mihai-Emil Gherghina, Ileana Peride, Mirela Ţigliş, Tiberiu Paul Neagu, Andrei Niculae, Ionel Alexandru Checheriţă,
Background: The connection between uric acid (UA) and renal impairment is well known due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging studies allege a new hypothesis concerning UA and renal impairment involving a pro-inflammatory status, endothelial dysfunction, and excessive activation of renin–angiotensin–aldosterone system (RAAS). Additionally, hyperuricemia associated with oxidative stress is incriminated in DNA damage, oxidations, inflammatory cytokine ...
Tópico(s): Case Reports on Hematomas
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Andrei Niculae, Ileana Peride, Mirela Ţigliş, Evgeni Sharkov, Tiberiu Paul Neagu, Ioan Lascăr, Ionel Alexandru Checheriţă,
Severe burn injuries lead to acute kidney injury (AKI) development, increasing the mortality risk up to 28-100%. In addition, there is an increase in hospitalization days and complications appearance. Various factors are responsible for acute or late AKI debut, like hypovolemia, important inflammatory response, excessive load of denatured proteins, sepsis, and severe organic dysfunction. The main measure to improve the prognosis of these patients is rapidly recognizing this condition and reversing ...
Tópico(s): Trauma, Hemostasis, Coagulopathy, Resuscitation
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Andrei Alexandru Boroiu, Elena Neagu, Andrei Alexandru Boroiu, Ionel Vieru,
In order to identify the possibilities for solving the traffic problems in the central area of Pitesti municipality - from improving traffic-light intersections to the proposal to redirect some of the traffic flows outside the area under analysis - a Vissim application, consisting of a microsimulation of road traffic in the central area, was performed. Based on the research conducted, a perspective of great interest proved to be the identification of the possibilities by means of which, to an extent ...
Tópico(s): Transportation Systems and Logistics
2018 - IOP Publishing | IOP Conference Series Materials Science and Engineering
Irina Băran, Diana N. Ionescu, Alexandru Filippi, Maria‐Magdalena Mocanu, Adrian Iftime, Ramona Madalina Babes, Ioana Teodora Tofolean, Ruxandra Irimia, Alexandru Goicea, Valentin Popescu, Alexandru Dimancea, Andrei Neagu, Constanţa Ganea,
The flavonoid quercetin and menadione (vitamin K3) are known as potent apoptogens in human leukemia Jurkat T cells. We explored some underlying mechanisms and the potential relevance of the combination quercetin-menadione for clinical applications. In acute treatments, quercetin manifested a strong antioxidant character, but induced a transient loss of Δψm, likely mediated by opening of the mitochondrial permeability transition pore. After removal of quercetin, persistent mitochondrial hyperpolarization ...
Tópico(s): Vitamin K Research Studies
2014 - Elsevier BV | Leukemia Research
Mădălina Zamfir, Vladimir Florian, Alexandru Stanciu, Gabriel Neagu, Ştefan Preda, Gheorghe Militaru,
The Internet of Things (IoT) is a priority topic for research and innovation in ICT as well as a major trend for its development in the next period. Due to the large variety of IoT based solutions and their economic and social impact, the healthcare is among most relevant application domains to illustrate this trend. The paper presents the main adopted design and development decisions to build a platform for prototyping IoT based assistive applications with health monitoring capabilities. The prototyping ...
Tópico(s): IoT Networks and Protocols
2016 - Springer Science+Business Media | Lecture notes in business information processing
Dan Alexandru Szabo, Nicolae Neagu, Ioan Sabin Sopa,
Tópico(s): Sports and Physical Education Research
2020 - | Health Sports & Rehabilitation Medicine
Dan Alexandru Szabo, Nicolae Neagu, Silvia Teodorescu, Corina Predescu, Ioan Sabin Sopa, Loredana Panait,
It has been estimated that between 30 and 50 per cent of all injuries that take place throughout participation in a sport are the consequence of soft tissue injuries, and muscle injuries are the primary cause of physical disability.The current literature review was designed between October 2021 and April 2022, according to the PRISMA standards, using the PubMed, Scopus, and Web of Science databases. At the screening stage, we eliminated articles that did not fit into the themes developed in all ...
Tópico(s): Sports injuries and prevention
2022 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Mirela Ţigliş, Ileana Peride, Iulia Alexandra Florea, Andrei Niculae, Lucian Cristian Petcu, Tiberiu Paul Neagu, Ionel Alexandru Checheriţă, I. Grintescu,
Population-based studies regarding renal replacement therapy (RRT) used in critical care populations are useful to understand the trend and impact of medical care interventions. We describe the use of RRT and associated outcomes (mortality and length of intensive care stay) in a level 1 hospital.
Tópico(s): Dialysis and Renal Disease Management
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Gabriel Neagu, Marilena Ianculescu, Adriana Alexandru, Vladimir Florian, Constanța Zoie Rădulescu,
The next generation of IoT is characterized by the usage of smart solutions with embedded intelligence at the edge that relies on high connectivity, processing capabilities for edge devices and real-time analysis of information. This evolution is based on the convergence of some key ICT technologies like hyperconnectivity and new network architectures, edge computing, artificial intelligence, and blockchain. Considering the high expectations regarding the wide use in various domains of the new, ...
Tópico(s): Blockchain Technology Applications and Security
2019 - Elsevier BV | Procedia Computer Science
Alexandra Neagu, Adela-Ioana Mocanu, Alexandru Bonciu, Gabriella Coadă, Horia Mocanu,
Although etiologically heterogeneous at least 50% of all early on‑set hearing losses have a genetic cause and of these, the large majority, 75‑80% are most probably autosomal recessive and 70% are non‑syndromic. The rest of the congenital hearing losses are determined by clinical and environmental factors such as ototoxic medication, prematurity, and complications at birth. During the last decade it became clear that 50‑80% of all such afflictions result from mutations in a single gene, GJB2 , which ...
Tópico(s): Neuroscience of respiration and sleep
2021 - Spandidos Publishing | Experimental and Therapeutic Medicine
Dan Alexandru Szabo, Nicolae Neagu, Silvia Teodorescu, Ioan Sabin Sopa,
Tópico(s): Children's Physical and Motor Development
2020 - | Health Sports & Rehabilitation Medicine
Dan Alexandru Szabo, Nicolae Neagu, Silvia Teodorescu, Ciprian Marius Panait, Ioan Sabin Sopa,
Currently, sports activities require a high reaction speed, coordination, and balance, highlighting the relationship between proprioceptive control, visual control, and hand-eye coordination in youth. The present research assessed the proprioceptive control, reaction speed, and lower limb balance of youth from five different schools to identify the level of physical preparation of children in this direction. This prospective study was conducted between 1 January 2020 and 29 February 2020. A total ...
Tópico(s): Sports and Physical Education Research
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
V. Ionescu, Alexandra Popa, Andrei Alexandru, Emilia Manole, Mihaela Neagu, Sevinci Pop,
The impact of dietary phytoestrogens on human health has been a topic of continuous debate since their discovery. Nowadays, based on their presumptive beneficial effects, the amount of phytoestrogens consumed in the daily diet has increased considerably worldwide. Thus, there is a growing need for scientific data regarding their mode of action in the human body. Recently, new insights of phytoestrogens’ bioavailability and metabolism have demonstrated an inter-and intra-population heterogeneity ...
Tópico(s): Diet, Metabolism, and Disease
2021 - Multidisciplinary Digital Publishing Institute | Antioxidants
Mariana Ardelean, Nicolae Neagu, Dan Alexandru Szabo,
Tópico(s): Sports Science and Education
2020 - | Health Sports & Rehabilitation Medicine
Dan Alexandru Szabo, Nicolae Neagu, Septimiu Voidăzan, Ioan Sabin Sopa, Camelia Gliga,
Tópico(s): Sports Analytics and Performance
2019 - | Health Sports & Rehabilitation Medicine
Andrei Alexandru Boroiu, Ion Tabacu, Alexandru Ene, Elena Neagu, Andrei Alexandru Boroiu,
For modelling road traffic at the level of a road network it is necessary to specify the flows of all traffic currents at each intersection. These data can be obtained by direct measurements at the traffic light intersections, but in the case of a roundabout this is not possible directly and the literature as well as the traffic modelling software doesn't offer ways to solve this issue. Two sets of formulas are proposed by which all traffic flows from the roundabouts with 3 or 4 arms are calculated ...
Tópico(s): Vehicle emissions and performance
2017 - IOP Publishing | IOP Conference Series Materials Science and Engineering
Gina Gheorghe, Anca Pantea Stoian, Mihnea‐Alexandru Găman, Bogdan Socea, Tiberiu Paul Neagu, Ana Maria Alexandra Stănescu, Ovidiu Gabriel Bratu, Dan Mischianu, Andra‐Iulia Suceveanu, Camelia Cristina Diaconu,
Chronic liver diseases are a public health issue, because of their high incidence and prevalence, the important impact on the quality of life and high mortality rates. From a pathogenic point of view, in almost all liver diseases there is an increase in oxidative stress. Oxidative stress represents as an imbalance between the production of oxidizing agents and antioxidants. This imbalance contributes to the initiation and progression of hepatic injury. Among the most important risk factors for increased ...
Tópico(s): Liver Disease Diagnosis and Treatment
2019 - Revista de Chimie | Revista de Chimie
Ileana Peride, Mirela Ţigliş, Tiberiu Paul Neagu, Andrei Niculae, Ionel Alexandru Checheriţă,
Chronic kidney disease (CKD) is associated with different complications, including chronic kidney disease–mineral and bone disorder (CKD–MBD), which represents a systemic disorder that involves the presence of different mineral or bone structure abnormalities (i.e., modification of bone turnover, strength, volume, etc.), including even vascular calcification development. Even if, over the years, different pathophysiological theories have been developed to explain the onset and progression of CKD–MBD, ...
Tópico(s): Trace Elements in Health
2022 - Multidisciplinary Digital Publishing Institute | Diagnostics
Zenaida Chiţu, Fausto Tomei, Giulia Villani, Alessandro Di Felice, Giovanni Zampelli, I. C. Paltineanu, I. Vişinescu, Alexandru Dumitrescu, Marcel Bularda, Dumitru Neagu, Romulus Costache, Luca Ecaterina,
In recent decades, water scarcity has become a frequent and widespread phenomenon. Intensification of water scarcity will have economic impact on the main water-using sectors. The highest pressure on the water resources is exerted by agriculture. Irrigation is the largest consumer of the agriculture sector and the efficient use of water is of utmost importance. The aim of this study is to explore the capability of an innovative platform that combines Earth Observation data, weather forecasts and ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2020 - Multidisciplinary Digital Publishing Institute | Water
Eliza Manea, Raluca Jipa, Alexandru Milea, Antonia Roman, Georgiana Neagu, Adriana Hristea,
Introduction. Information on healthcare-associated C.difficile infection (HA-CDI) in COVID-19 patients is limited. We aimed to assess the characteristics of HA-CDI acquired during and before the COVID-19 pandemic. Methods. We conducted a retrospective study in a tertiary care hospital, in which since March 2020 exclusively COVID-19 patients are hospitalized. We compared HA-CDI adult patients hospitalized in March 2020-February 2021 with those hospitalized during the same period in 2017-2018. Results. ...
Tópico(s): Antibiotic Use and Resistance
2021 - De Gruyter | Romanian Journal of Internal Medicine
Ioana Gomoiu, Dan Mohanu, Roxana Rădvan, M. Dumbravician, Simona Neagu, Roxana Cojoc, Mădălin Enache, Alexandru Chelmuș, Ileana Mohanu,
The microclimate monitoring of Humor Monastery, Tismana Monastery and the refectory of Hurezi monastic complex from Romania was performed in order to investigate its effect on the growth of bacteria isolated from infilling mortar.According to the results, microclimate parameters values in Humor Monastery and the refectory of Hurezi monastic complex were similar but specific for each season due to the absence of central heating.Opposite, in Tismana Monastery with central heating, no remarkable differences ...
Tópico(s): Microbial Metabolism and Applications
2017 - Polish Academy of Sciences | Acta Physica Polonica A
Mariana Ardelean, Nicolae Neagu, Dan Alexandru Szabo,
The aim of this research is to identify and analyse the causes that have influenced the total number of student places and career paths of graduates of a sports-program high school. In this sociological research, the case study method was used, which had in the foreground the Sports Program Suceava High school, from Romania. The sampling comprised the high school grade students (XI-XII), registered from September 2015 to August 2019. The objectives of the study are to determine the main variables ...
Tópico(s): Physical Education and Training Studies
2021 - | Revista Romaneasca pentru Educatie Multidimensionala
Cristian Cobilinschi, R.C. Tincu, Claudia Cobilinschi, Tiberiu Paul Neagu, Gabriel Becheanu, Ruxandra-Diana Sinescu, Ionel Alexandru Checheriţă, I. Grintescu, Ioan Lascăr,
Organophosphate (OP) use remains largely available worldwide despite more strict regulatory measures, in agriculture, parks or households, leading to a daily low-dose exposure.The systemic dysfunction appears partly due to acetylcholinesterase inhibition, exhibiting a primary toxic effect on the endocrine system but also on the liver and kidneys, which are responsible for products metabolization and elimination.Prolonged OP exposure can be responsible for histopathological (HP) changes that can either ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2020 - Romanian Academy's Publishing House | Romanian Journal of Morphology and Embryology
Dan Alexandru Szabo, Nicolae Neagu, Horațiu Popoviciu, Simona Szasz, Tudor Andrei Șopterean, Roxana Mihaela Munteanu,
Abstract Purpose The following research highlighted the importance of the TECAR therapy in recovering after anterior cruciate ligament surgery in performance athletes. Methods The study took place at Fizionova Medical Recovery Center in Targu Mures, on a period of 6 weeks between 24.01.2020 and 07.03.2020, on a sample of 10 subjects with anterior cruciate ligament surgery (5 subjects in the experiment group that followed the TECAR recovery program and 5 subjects that only followed a physiotherapy ...
Tópico(s): Total Knee Arthroplasty Outcomes
2020 - Mirton Publishing House, Timisoara | Timisoara Physical Education and Rehabilitation Journal