Andrés Pichón-Rivière, Michael Drummond, Alfredo Palacios, Sebastián García Martí, Federico Augustovski,
BackgroundAssessment of the efficiency of interventions is paramount to achieving equitable health-care systems. One key barrier to the widespread use of economic evaluations in resource allocation decisions is the absence of a widely accepted method to define cost-effectiveness thresholds to judge whether an intervention is cost-effective in a particular jurisdiction. We aimed to develop a method to estimate cost-effectiveness thresholds on the basis of health expenditures per capita and life expectancy ...
Tópico(s): Global Maternal and Child Health
2023 - Elsevier BV | The Lancet Global Health
Adriana Palacios, Alfredo Córdova Lizama, P.M. Castro-Olivera, Erika Palacios Rosas,
The use of hydrogen is increasing in many countries due to potential decarbonization and sustainable energy transition projects. Hydrogen is shown to be a versatile transition alternative in different applications, with an increasing trend towards clean alternatives with better performance improving the existing processes. This paper reviews (i) the international panorama of hydrogen production, (ii) the main alternatives for hydrogen production in Mexico, and (iii) the applications of hydrogen in ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2022 - Elsevier BV | International Journal of Hydrogen Energy
Amaha del Palacio, Alfredo Perez-Revilla, Rosa Albanil, Teresa Sotelo, Debra Chester Kalter,
del Palacio, Amaha M.D.; Perez-Revilla, Alfredo M.D.; Albanil, Rosa M.D.; Sotelo, Teresa M.D.; Kalter, D. Chester M.D. Author Information
Tópico(s): Congenital Diaphragmatic Hernia Studies
1990 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Ernesto Garcı́a-Rubi, D. Vazquez‐Alemán, Juan Pablo Méndez, Jorge Salinas, J. Garza‐Flores, Samuel Ponce‐de‐León, Gregorio Pérez‐Palacios, Alfredo Ulloa‐Aguirre,
Summary OBJECTIVE We examined the functional status of the hypothalamic‐opioid system involved in LH secretion and the pituitary LH sensitivity and reserve in patients with anorexia nervosa were studied during body weight loss and weight recovery. We measured the temporal relationship between weight recovery, expression of hypothalamic‐opioid activity and pituitary GnRH responsiveness, and resumption of ovulatory cycles. DESIGN Five patients with anorexia nervosa were prospectively studied during ...
Tópico(s): Menstrual Health and Disorders
1992 - Wiley | Clinical Endocrinology
José Ignacio Rodrı́guez, José Palacios, Alfredo García‐Alix, I. Pastor, Ricardo Paniagua,
Tópico(s): Congenital Anomalies and Fetal Surgery
1988 - Springer Science+Business Media | Calcified Tissue International
Antonio Gallardo, José María Fernández‐Palacios, Alfredo Bermúdez, Lea de Nascimento, Jorge Durán, Laura García‐Velázquez, Javier Méndez, Alexandra Rodríguez,
Tópico(s): Atmospheric chemistry and aerosols
2020 - Springer Science+Business Media | Biogeochemistry
Miguel Ángel Suárez-Rosales, Raúl Pinto-Segura, Elia G. Palacios, Alfredo Hernández-Herrera, F. Chávez,
The combined processes; rapid solidification, addition of Cu3P compound and heat treatments to improve the mechanical properties of the hypereutectic Al-13Si, Al-20Si and Al-20Si-1.5Fe-0.7Mn alloys (in wt. %) was studied. Optical microscopy and scanning electron microscopy were used to characterize the microstructures. The mechanical properties were evaluated by tensile tests. It was found that the cooling rate (20-50°C/s) used to solidify the alloys plus the addition of Cu3P compound favored the formation ...
Tópico(s): Microstructure and mechanical properties
2016 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research
Matthew J. Kohn, Caroline A. E. Strömberg, Richard H. Madden, Regan E. Dunn, S. Evans, Alma Palacios, Alfredo A. Carlini,
New local/regional climatic data were compared with floral and faunal records from central Patagonia to investigate how faunas evolve in the context of local and global climates. Oxygen isotope compositions of mammal fossils between c. 43 and 21 Ma suggest a nearly constant mean annual temperature of 16 ± 3 °C, consistent with leaf physiognomic and sea surface studies that imply temperatures of 16–18 °C. Carbon isotopes in tooth enamel track atmospheric δ13C, but with a positive deviation at 27.2 Ma, ...
Tópico(s): Plant Diversity and Evolution
2015 - Elsevier BV | Palaeogeography Palaeoclimatology Palaeoecology
Juan Carlos Castillo, Diego Palacios, Alfredo Joignant, Maximiliano Tham,
Political participation has frequently been associated with individual resources; that is, individuals with higher incomes, higher educational levels and more time tend to participate in the political process to a greater extent than other individuals do. The present study suggests that in addition to resources, an individual's beliefs about economic distribution are an important determinant of participation both in elections and in protests. Based on the analysis of the Chilean data from the Latin ...
Tópico(s): Social Capital and Networks
2015 - Wiley | Bulletin of Latin American Research
Juan Luis Mosqueda-Gómez, Aldo J. Montaño‐Loza, Ana Lilia Rolón, Carlos Cervantes, Miriam Bobadilla-del-Valle, Jesús Silva-Sánchez, Ulises Garza–Ramos, Angelina Villası́s-Keever, Arturo Galindo‐Fraga, Guillermo M. Ruiz Palacios, Alfredo Ponce‐de‐León, José Sifuentes‐Osornio,
ObjectivesTo study the prevalence, risk factors, outcome, and molecular epidemiology in patients with bacteremia caused by extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae (Kp) (cases), in comparison with patients with bacteremia caused by a susceptible Kp (controls).MethodsThis was a retrospective case–control study including all episodes of Kp bacteremia for the period 1993 to 2002 at a referral hospital for adults in Mexico. ESBL production was tested for by E-test. All isolates ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2008 - Elsevier BV | International Journal of Infectious Diseases
Diego Esteban‐Fernández, Marı́a Montes-Bayón, Elisa Blanco González, M. Milagros Gómez-Gómez, M. A. Palacios, Alfredo Sanz‐Medel,
The judicious use of cis-Pt as an intravenously administrable Pt(II) drug for chemotherapy requires the evaluation of its interactions with blood proteins. Therefore, the combined use of modern analytical chemical speciation and of analytical proteomics approaches to study these interactions is described here. The method involves incubation of cis-Pt with standard proteins and human serum samples. The separation of the proteins is conducted by liquid chromatography in an anion exchange column (Mono ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2008 - Royal Society of Chemistry | Journal of Analytical Atomic Spectrometry
Patricia Canto, Felipe Vilchis, Bertha Chávez, Osvaldo M. Mutchinick, Julianne Imperato‐McGinley, Gregorio Pérez‐Palacios, Alfredo Ulloa‐Aguirre, Juan Méndez,
BACKGROUND AND OBJECTIVE Male pseudohermaphroditism due to 5α‐reductase deficiency was originally described in 1974. Recently, 5α‐reductase Type 2 gene defects have been found generally to be due to point mutations within the 5 exons of the 5α‐reductase‐2 gene. In this report, we describe the molecular study of patients with 5α‐reductase deficiency. DESIGN Previously diagnosed patients with 5α‐reductase deficiency were sampled in order to perform molecular studies. PATIENTS Eight 5α‐reductase deficient ...
Tópico(s): Urologic and reproductive health conditions
1997 - Wiley | Clinical Endocrinology
Miguel A. Parada, Carlos Palacios, Alfredo Lahsen,
Tópico(s): earthquake and tectonic studies
1997 - Springer Science+Business Media | Mineralium Deposita
Alfredo E. Rodríguez, Igor F. Palacios, Alfredo M. Rodríguez-Granillo, Juan Mieres, Sonia Tarragona, Carlos Fernández‐Pereira, Leonardo Solórzano, Ricardo Pauletto, Patrick W. Serruys, David Antoniucci,
The aim of this study was to compare 5-year cost-effectiveness and clinical outcomes of patients with oral rapamycin (OR) plus bare-metal stent versus the drug-eluting stent (DES) strategy. During 2006 to 2007, a total of 200 patients were randomized to OR (n = 100) and DES (n = 100). Primary end point was to compare costs of initial procedure and cost-effectiveness of both revascularization strategies. Safety was evaluated by the composite of death, myocardial infarction, and cerebrovascular accident. ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2013 - Elsevier BV | The American Journal of Cardiology
A.K. Román-Ruiz, Edi A. Malo, Graciela Huerta‐Palacios, Alfredo Castillo, Juan F. Barrera, Julio C. Rojas,
Tópico(s): Plant Parasitism and Resistance
2012 - Springer Science+Business Media | Arthropod-Plant Interactions

Andrés Pichón-Rivière, Ariel Bardach, Federico Rodríguez Cairoli, Agustín Casarini, Natalia Espínola, Lucas Perelli, Luz Myriam Reynales-Shigematsu, Blanca Llorente, Márcia Pinto, Belén Saénz de Miera Juárez, Tatiana Villacrés, Esperanza Peña Torres, Nydia Amador, César Antonio Loza Munarriz, Marianela Castillo‐Riquelme, Javier Roberti, Federico Augustovski, Andrea Alcaraz, Alfredo Palacios,
To investigate the tobacco-attributable burden on disease, medical costs, productivity losses and informal caregiving; and to estimate the health and economic gains that can be achieved if the main tobacco control measures (raising taxes on tobacco, plain packaging, advertising bans and smoke-free environments) are fully implemented in eight countries that encompass 80% of the Latin American population.
Tópico(s): Obesity, Physical Activity, Diet
2023 - BMJ | Tobacco Control
Edgar Cortés Gallardo Medina, Victor Miguel Velazquez Espitia, Daniela Chípuli Silva, Sebastián Fernández Ruiz de las Cuevas, Marco Palacios Hirata, Alfredo Zhu Chen, José Ángel González, Rogelio Bustamante-Bello, Carlos Francisco Moreno‐García,
Autonomous vehicles are increasingly becoming a necessary trend towards building the smart cities of the future. Numerous proposals have been presented in recent years to tackle particular aspects of the working pipeline towards creating a functional end-to-end system, such as object detection, tracking, path planning, sentiment or intent detection, amongst others. Nevertheless, few efforts have been made to systematically compile all of these systems into a single proposal that also considers the ...
Tópico(s): Autonomous Vehicle Technology and Safety
2021 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Andrea Alcaraz, Andrés Pichón-Rivière, Alfredo Palacios, Ariel Bardach, Darío Balan, Lucas Perelli, Federico Augustovski, Agustín Ciapponi,
Abstract Background Around 184,000 deaths per year could be attributable to sugar-sweetened beverages (SSBs) consumption worldwide. Epidemiological and decision models are important tools to estimate disease burden. The purpose of this study was to identify models to assess the burden of diseases attributable to SSBs consumption or the potential impact of health interventions. Methods We carried out a systematic review and literature search up to August 2018. Pairs of reviewers independently selected, ...
Tópico(s): Global Public Health Policies and Epidemiology
2021 - BioMed Central | BMC Public Health
Lucas González, Ariel Bardach, Alfredo Palacios, Claudia Peckaitis, Agustín Ciapponi, Andres Pichón-Riviere, Federico Augustovski,
Breast cancer (BC) is the most common cancer in women. It imposes a huge disease burden and a significant impact on health-related quality of life (HRQoL). Our study focused on HRQoL of patients with BC in Latin America and the Caribbean (LAC). We conducted a systematic review to identify relevant articles published between 2008 and August 2018. We conducted several meta-analyses and subgroup analyses by country, disease stage, and instrument used (Prospective Register Of Systematic Reviews registration ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2021 - AlphaMed Press | The Oncologist
Agustín Ciapponi, Federico Rodríguez Cairoli, Germán Solioz, Carlos Rojas‐Roque, Akram Hernández-Vasquéz, Alfredo Palacios, Ariel Bardach,
Objetivos. Evaluar cómo y en qué medida se produce un intercambio desde los cigarrillos convencionales (CC) a los sistemas electrónicos de administración de nicotina (SEAN). Materiales y métodos. Se realizó una revisión sistemática hasta agosto de 2019. El desenlace primario fue la proporción de un intercambio completo o parcial de CC a los SEAN y sus aspectos económicos. Los desenlaces secundarios como medidas de resultado fueron la probabilidad de intercambio y la tendencia en el intercambio por ...
Tópico(s): Obesity, Physical Activity, Diet
2021 - National Institute of Health of Peru | Revista Peruana de Medicina Experimental y Salud Pública

Andrés Pichón-Rivière, Andrea Alcaraz, Alfredo Palacios, Belén Rodríguez, Luz Myriam Reynales-Shigematsu, Márcia Pinto, Marianela Castillo‐Riquelme, Esperanza Peña Torres, Diana Isabel Osorio, Leandro Huayanay, César Antonio Loza Munarriz, Belén Sáenz de Miera-Juárez, Verónica Gallegos-Rivero, Catherine De La Puente, María del Pilar Navía-Bueno, Joaquín Caporale, Javier Roberti, Sacha Alexis Virgilio, Federico Augustovski, Ariel Bardach,
BackgroundWorldwide, smoking tobacco causes 7 million deaths annually, and this toll is expected to increase, especially in low-income and middle-income countries. In Latin America, smoking is a leading risk factor for death and disability, contributes to poverty, and imposes an economic burden on health systems. Despite being one of the most effective measures to reduce smoking, tobacco taxation is underused and cigarettes are more affordable in Latin America than in other regions. Our aim was ...
Tópico(s): Smoking Behavior and Cessation
2020 - Elsevier BV | The Lancet Global Health
Marianela Castillo‐Riquelme, Ariel Bardach, Alfredo Palacios, Andrés Pichón-Rivière,
Background Globally, tobacco consumption continues to cause a huge burden of preventable diseases. Chile has been leading the tobacco burden ranking in the Latin American region for the last ten years; it has currently a 33. 3% prevalence of current smokers. Methods A microsimulation economic model was developed within the framework of a multi-country project in order to estimate the burden attributable to smoking in terms of morbidity, mortality, disability-adjusted life-years (DALYs), and direct ...
Tópico(s): Obesity, Physical Activity, Diet
2020 - Public Library of Science | PLoS ONE
Alfredo Palacios, Natalia Espínola, Carlos Rojas‐Roque,
The high fragmentation and decentralization in the provision of health care services that characterizes Argentina's health system, as well as the economic and social inequalities, challenge the achievement of the Universal Health Coverage (UHC). The objective of this study is to measure socioeconomic-related inequality and horizontal inequity in the use of health care services in Argentina as well as identify the factors that contribute to these disparities.The 2013 National Risk Factor Survey, developed ...
Tópico(s): Healthcare Policy and Management
2020 - BioMed Central | International Journal for Equity in Health
Leixuri Aguirre, Sara Palacios-Ortega, Alfredo Fernández‐Quintela, Elizabeth Hijona, Luís Bujanda, María P. Portillo,
Excessive fat accumulation within the liver is known as "simple hepatic steatosis", which is the most benign form of non-alcoholic fatty liver disease (NAFLD). The aim of the present study was to determine whether pterostilbene improves this hepatic alteration in Zucker (fa/fa) rats. Animals were distributed in two experimental groups (n = 10) and fed a standard laboratory diet. Rats in the pterostilbene group were given a dose of 30 mg/kg body weight/d for six weeks. After sacrifice, serum glucose, transaminase, ...
Tópico(s): Lipid metabolism and biosynthesis
2019 - Multidisciplinary Digital Publishing Institute | Nutrients

Márcia Pinto, Ariel Bardach, Alfredo Palacios, Aline Navega Biz, Andrea Alcaraz, Belén Rodríguez, Federico Augustovski, Andrés Pichón-Rivière,
The prevalence of smoking in Brazil has decreased considerably in recent decades, but the country still has a high burden of disease associated with this risk factor. The study aimed to estimate the burden of mortality, morbidity, and costs for society associated with smoking in 2015 and the potential impact on health outcomes and the economy based on price increases for cigarettes through taxes. Two models were developed: the first is a mathematical model based on a probabilistic microsimulation ...
Tópico(s): Smoking Behavior and Cessation
2019 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Ariel Bardach, Andrea Alcaraz, Agustín Ciapponi, Osvaldo Ulises Garay, Andrés Pichón-Rivière, Alfredo Palacios, Mariana Cremonte, Federico Augustovski,
Around 6% of total deaths are related to alcohol consumption worldwide. Mathematical models are important tools to estimate disease burden and to assess the cost-effectiveness of interventions to address this burden.We carried out a systematic review on models, searching main health literature databases up to July 2017. Pairs of reviewers independently selected, extracted data and assessed the quality of the included studies. Discrepancies were resolved by consensus. We selected those models exploring: ...
Tópico(s): Alcohol Consumption and Health Effects
2019 - BioMed Central | BMC Public Health
Osvaldo Ulises Garay, Alfredo Palacios, Andrés Pichón-Rivière, Federico Augustovski, Sebastián García Martí, Akram Hernández-Vasquéz, Elena Tapia, Guillermo Rosa-Díez, Ariel Bardach,
Acute kidney injury (AKI) is a public health problem that affects millions of hospitalized patients worldwide. In Argentina, evidence suggests that its incidence has risen in recent years. When severe, AKI may require a renal replacement therapy (RRT) where continuous RRT (CRRT) and intermittent RRT (IRRT) are plausible options for patients in the intensive care unit.To evaluate the cost utility of CRRT versus IRRT for the National Institute of Social Services for Retirees and Pensioners, the largest ...
Tópico(s): Chronic Kidney Disease and Diabetes
2019 - Elsevier BV | Value in Health Regional Issues
José M. Lárraga‐Gutiérrez, Olivia Amanda García‐Garduño, C. G. Treviño-Palacios, José Alfredo Herrera-González,
Flatbed scanners are the most frequently used reading instrument for radiochromic film dosimetry because its low cost, high spatial resolution, among other advantages. These scanners use a fluorescent lamp and a CCD array as light source and detector, respectively. Recently, manufacturers of flatbed scanners replaced the fluorescent lamp by light emission diodes (LED) as a light source. The goal of this work is to evaluate the performance of a commercial flatbed scanner with LED based source light ...
Tópico(s): Radiation Detection and Scintillator Technologies
2018 - Elsevier BV | Physica Medica
Federico Augustovski, Martín Chaparro, Alfredo Palacios, Lizheng Shi, Andrea Beratarrechea, Vilma Irazola, Adolfo Rubinstein, Katherine T. Mills, Jiang He, Andrés Pichón-Rivière,
BackgroundA recent cluster randomized trial evaluating a multicomponent intervention showed significant reductions in blood pressure in low-income hypertensive subjects in Argentina.ObjectivesTo assess the cost-effectiveness of this intervention.MethodsA total of 1432 hypertensive participants were recruited from 18 primary health care centers. The intervention included home visits led by community health workers, physician education, and text messaging. Resource use and quality of life data using ...
Tópico(s): Healthcare Systems and Reforms
2018 - Elsevier BV | Value in Health
Ariel Bardach, Felicia Cañete, Guillermo Sequera, Alfredo Palacios, Andrea Alcaraz, Belén Rodríguez, Joaquín Caporale, Federico Augustovski, Andrés Pichón-Rivière,
Objectives. To consider the burden of disease associated to tobacco consumption in Paraguay and to evaluate the potential economic and health effect of price increase through taxes. Materials and Methods. A Monte Carlo simulation model was designed incorporating natural history, costs, and quality of life of diseases associated to smoking for 2015. Also, several scenarios were considered for the impact of tax raises on the prevalence of smoking and fiscal collection. Results. In Paraguay, 3,354 ...
Tópico(s): Global Public Health Policies and Epidemiology
2018 - National Institute of Health of Peru | Revista Peruana de Medicina Experimental y Salud Pública