Produção Nacional
Revisado por pares
Priscilla Ribeiro dos Santos, Alfredo Alejandro Gugliano,
Resumo Na última década, o governo brasileiro diversificou os fóruns de interlocução com a sociedade civil na gestão das políticas públicas. Com base nessa proposta, o Conselho de Desenvolvimento Econômico e Social (CDES) foi criado em 2003 para assessorar a Presidência da República quanto às políticas desenvolvimentistas. Este artigo tem como objetivo analisar a efetividade do CDES no que tange a interlocução com a sociedade civil e a incidência no processo decisório das políticas governamentais ...
Tópico(s): Social and Political Issues
2015 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista de Sociologia e Política
Produção Nacional
Revisado por pares
Lívia de Jesus Vieira, Taliane Leila Soares, Mônica Lanzoni Rossi, Alfredo Augusto Cunha Alves, Francisco de Assis Ribeiro dos Santos, Fernanda Vidigal Duarte Souza,
The objective of this work was to characterize the viability, production and morphology of pollen for different species in the genus Manihot. Floral buds from Manihot accessions were collected from two germplasm banks at Embrapa Cassava & Fruits. The viability of the pollen was assessed via colorimetric, in vitro and in vivo assays. The diameter of the pollen grains was determined by measuring the transversal length of the grain. The experimental design was entirely randomized. Studies on pollen ultrastructure ...
Tópico(s): Plant Reproductive Biology
2012 - Sociedade Botânica do Brasil | Acta Botanica Brasilica
Produção Nacional
Revisado por pares
Petra Barros dos Santos, Juliana Silva Zanetti, Alfredo Ribeiro‐Silva, Eduardo IC Beltrão,
The main focus of several studies concerned with cancer progression and metastasis is to analyze the mechanisms that allow cancer cells to interact and quickly adapt with their environment. Integrins, a family of transmembrane glycoproteins, play a major role in invasive and metastatic processes. Integrins are involved in cell adhesion in both cell-extracellular matrix and cell-cell interactions, and particularly, β1 integrin is involved in proliferation and differentiation of cells in the development ...
Tópico(s): HER2/EGFR in Cancer Research
2012 - BioMed Central | Diagnostic Pathology
Produção Nacional
Revisado por pares
Aliny Pereira de Lima, Flávia de Castro Pereira, César Augusto Sam Tiago Vilanova-Costa, Alessandra de Santana Braga Barbosa Ribeiro, Luiz Alfredo Pavanin, Wagner Batista dos Santos, Elisângela de Paula Silveira-Lacerda,
Tópico(s): Chromium effects and bioremediation
2010 - Springer Science+Business Media | Journal of Biosciences
Produção Nacional
Revisado por pares
M.M.S.G. Cardena, Ândrea Ribeiro‐dos‐Santos, Sidney Emanuel Batista dos Santos, Alfredo José Mansur, Alexandre C. Pereira, Cíntia Fridman,
Heart failure (HF) is a chronic limiting disease associated with high morbidity and mortality [1Lindenfeld J. Albert N.M. Boehmer J.P. et al.HFSA 2010 comprehensive heart failure practice guideline.J Card Fail. 2010; 16: e1-e194Abstract Full Text Full Text PDF PubMed Scopus (828) Google Scholar, 2Godoy H.L. Silveira J.A. Segalla E. Almeida D.R. Hospitalização e mortalidade por insuficiência cardíaca em hospitais públicos no município de São Paulo.Arq Bras Cardiol. 2011; 97: 402-407Crossref PubMed Scopus ( ...
Tópico(s): Hemoglobinopathies and Related Disorders
2014 - Elsevier BV | International Journal of Cardiology
Produção Nacional
Revisado por pares
M.M.S.G. Cardena, Ândrea Ribeiro‐dos‐Santos, Sidney Emanuel Batista dos Santos, Alfredo José Mansur, Alexandre C. Pereira, Cíntia Fridman,
In populations that have a high degree of admixture, such as in Brazil, the sole use of ethnicity self-declaration information is not a good method for classifying individuals regarding their ethnicity. Here, we evaluate the relationship of self-declared ethnicities with genomic ancestry and mitochondrial haplogroups in 492 individuals from southeastern Brazil. Mitochondrial haplogroups were obtained by analyzing the hypervariable regions of the mitochondrial DNA (mtDNA), and the genomic ancestry ...
Tópico(s): Molecular Biology Techniques and Applications
2013 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Zehra Köksal, Germán Burgos, Elizeu Fagundes de Carvalho, Sílvia Loiola, María Laura Parolín, Alfredo Quiroz, Ândrea Ribeiro‐dos‐Santos, Ulises Toscanini, Carlos Vullo, Claus Børsting, Leonor Gusmão, Vânia Pereira,
Y haplogroups, defined by Y-SNPs, allow the reconstruction of the human Y chromosome genealogy, which is important for population, evolutionary and forensic genetics. In this study, Y-SNPs were typed and haplogroups inferred with the MPS Ion AmpliSeq™ HID Y-SNP Research Panel v1, as a high-throughput approach. Firstly, the performance of the panel was evaluated with different DNA input amounts, reagent volumes and cycle numbers. DNA-inputs from 0.5 to 1 ng generated the most balanced read depth. ...
Tópico(s): Genetic diversity and population structure
2022 - Elsevier BV | Forensic Science International Genetics
Produção Nacional
Revisado por pares
Reginaldo Cruz Alves Rosa, Jessica Oliveira de Santis, Lorena Alves Teixeira, Greice Andreotti de Molfetta, Jennifer Thalita Targino dos Santos, Vanessa dos Santos Ribeiro, Fernando Chahud, Alfredo Ribeiro‐Silva, Mariângela Ottoboni Brunaldi, Wilson A. Silva, Victor Evangelista de Faria Ferraz,
To report the frequency of Lynch syndrome (LS) in a cohort of patients from Southeast Brazil bearing endometrial cancer (EC), using a tumor screening universal approach.A total of 242 endometrial carcinomas were screened by immunohistochemistry (IHC) and microsatellite instability (MSI) for detection of DNA mismatch repair deficiency (dMMR). MLH1 methylation was assessed to identify sporadic cases. Patients with dMMR tumors were recruited for germline variant analysis by next-generation sequencing of ...
Tópico(s): Cancer Genomics and Diagnostics
2020 - Elsevier BV | Gynecologic Oncology
Produção Nacional
Revisado por pares
Flávia de Castro Pereira, Aliny Pereira de Lima, César Augusto Sam Tiago Vilanova-Costa, Wanessa Carvalho Pires, Alessandra de Santana Braga Barbosa Ribeiro, Lucas Carlos Gomes Pereira, Luiz Alfredo Pavanin, Wagner Batista dos Santos, Elisângela de Paula Silveira-Lacerda,
Abstract Chemotherapy is a common treatment for leukemia. Ruthenium complexes have shown potential utility in chemotherapy and photodynamic therapy. The identification of new chemotherapeutics agents is critical for further progress in the treatment of leukemia. Ruthenium complexes generally have lower toxicities compared to cisplatin attributed to their specific accumulation in cancer tissues. Based on these evidences, in the present work we studied the cytotoxic activity of the ruthenium(III) ...
Tópico(s): DNA and Nucleic Acid Chemistry
2014 - Springer International Publishing | SpringerPlus
Luís Costa-Matos, Paulo Ricardo Batista, Nuno Monteiro, Maria José Simões, Conceição Egas, Jorge Pereira, Helena Pinho, Natália Gomes dos Santos, João Ribeiro, Maria Augusta Cipriano, Pedro Henriques, Fernando Girão, Alfredo José Rodrigues, Armando Carvalho,
Hepcidin plays a crucial role in iron metabolism, preventing its absorption at the basolateral enterocyte membrane. Hepcidin regulation is complex and regulated at the transcriptional level. The relation between iron overload and alcoholic liver disease is well known, but its mechanism is not clear. We present an observational, case-control study, aimed at evaluating the effects of alcohol on the expression of hepcidin in human participants. We intended to assess whether iron overload related to ...
Tópico(s): Hemoglobinopathies and Related Disorders
2012 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Produção Nacional
Revisado por pares
Aliny Pereira de Lima, Flávia de Castro Pereira, César Augusto Sam Tiago Vilanova-Costa, Francyelli Mello-Andrade, Alessandra de Santana Braga Barbosa Ribeiro, Polyana Lopes Benfica, Marize Campos Valadares, Luiz Alfredo Pavanin, Wagner Batista dos Santos, Elisângela de Paula Silveira-Lacerda,
Ruthenium(III) complexes are increasingly attracting the interest of researchers due to their promising pharmacological properties. In the present study, we investigated the ability of cis-(dichloro)tetrammineruthenium(III) chloride to produce lethal effects in human chronic myelogenous leukemia K562 cells. The MTT tetrazolium reduction test and the trypan blue exclusion assay revealed that the IC50 for the compound after 48 h of incubation with K562 cells was approximately 10.74 and 73.45 μM, respectively. ...
Tópico(s): Synthesis of Tetrazole Derivatives
2010 - Elsevier BV | Toxicology in Vitro
Produção Nacional
Revisado por pares
Aliny Pereira de Lima, Flávia de Castro Pereira, César Augusto Sam Tiago Vilanova-Costa, Jordana Ribeiro Soares, Lucas Carlos Gomes Pereira, Hellen Karine Paes Porto, Luiz Alfredo Pavanin, Wagner Batista dos Santos, Elisângela de Paula Silveira-Lacerda,
Tópico(s): Click Chemistry and Applications
2011 - Springer Science+Business Media | Biological Trace Element Research
Produção Nacional
Revisado por pares
Daniela Fernanda de Freitas, David F. Colón, Rangel L. Silva, Eloá Mangabeira Santos, Victor Hugo Dantas Guimarães, Guilherme Henrique Mendes Ribeiro, Alfredo Maurício Batista de Paula, André Luiz Sena Guimarães, Sidnei Tavares dos Reis, Fernando Q. Cunha, Maísa Mota Antunes, Gustavo Batista Menezes, Sérgio Henrique Sousa Santos,
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2022 - Springer Nature | Molecular Biology Reports
Produção Nacional
Revisado por pares
M.M.S.G. Cardena, Ândrea Ribeiro‐dos‐Santos, Sidney Emanuel Batista dos Santos, Alfredo José Mansur, Sabrina Bernardez‐Pereira, Paulo Caleb Júnior Lima Santos, Alexandre C. Pereira, Cíntia Fridman,
Tópico(s): Cardiovascular Function and Risk Factors
2015 - Springer Nature | Journal of Human Hypertension
Produção Nacional
Revisado por pares
Bruno Albuquerque de Castro, Vitor Vecina dos Santos, Guilherme Beraldi Lucas, Jorge Alfredo Ardila‐Rey, Rudolf Ribeiro Riehl, André Luiz Andreoli,
Dry-type insulated transformers stand out for their higher applicability in substations, high-voltage instrumentation systems, and electrical installations. In this machine, the insulation system is constituted of dielectric materials such as epoxy resin and Nomex paper. Some critical issues in the operation of this equipment, such as overload, moisture, or heat, can induce a slow degradation of the physical-chemical properties of the dielectric materials, which can culminate in the total failure ...
Tópico(s): Electrical Fault Detection and Protection
2022 - Multidisciplinary Digital Publishing Institute | Sensors
Produção Nacional
Revisado por pares
Andressa Leite Ferraz de Melo, Luana Rossato, Marcelo dos Santos Barbosa, Rhanany Alan Calloi Palozi, Tamaeh Monteiro‐Alfredo, Kátia Ávila Antunes, Junio Eduvirgem, Suzana M. Ribeiro, Simone Simionatto,
The emergence of resistance to antibiotics has become a global challenge as far as the control and treatment of nosocomial infections are concerned. Compared to the planktonic state, biofilms generally confer more resistance to antibiotics and may become a potential source of infection. Researchers are thus focused on developing novel drugs not as vulnerable as the current ones to bacterial resistance mechanisms and also able to target bacteria in biofilms. Natural products, especially those derived ...
Tópico(s): Phytochemistry and Bioactivity Studies
2022 - Elsevier BV | Microbiological Research
Produção Nacional
Revisado por pares
Luciana Torres Ribeiro, Gustavo Novelino Simão, A. L. M. Matos, Carlos Gilberto Carlotti, Benedicto Oscar Colli, Luciano Neder, Alfredo Ribeiro-Silva, Margaret de Castro, Eduardo Magalhães Rego, Antônio Carlos dos Santos,
Tópico(s): CNS Lymphoma Diagnosis and Treatment
2004 - Springer Science+Business Media | Neuroradiology
Produção Nacional
Revisado por pares
José Yure Gomes dos Santos, Suzana Maria Gico Lima Montenegro, Richarde Marques da Silva, Celso Augusto Guimarães Santos, Nevil Quinn, Ana Paula Campos Xavier, Alfredo Ribeiro Neto,
Water management in the Caatinga/Atlantic forest ecotone in Brazil is critically dependent on better understanding of potential future changes in streamflow and sediment dynamics. This paper evaluates both the future impacts of land use and land cover (LULC) changes and the impacts of climate change on the streamflow and sediment yield in the Tapacurá River basin in northeastern Brazil, using a novel combination of approaches. Projected climate data derived using global circulation model HadGEM2- ...
Tópico(s): Flood Risk Assessment and Management
2021 - Elsevier BV | CATENA
Produção Nacional
Yan Ranny Machado Gomes, Marcella Vasconcelos Quintella Jucá, Larissa Ferreira David Romão Batista, Alfredo Ribeiro Neto, Sylvana Melo dos Santos,
Tópico(s): Groundwater and Watershed Analysis
2021 - Springer Science+Business Media | Sustainable Water Resources Management
Produção Nacional
Diêgo Cézar dos Santos Araújo, Suzana Maria Gico Lima Montenegro, Alfredo Ribeiro Neto, Samara Fernanda da Silva,
The Northeast region of Brazil, particularly the Brazilian semiarid region (BSR), is frequently affected by drought events, such as the great drought that started in 2012 and is considered one of the most severe droughts in recent decades. Monitoring and quantifying this type of event is essential for decision-making and the adoption of impact mitigation strategies. In this study, remotely sensed soil moisture (SM) data from three products derived from Soil Moisture and Ocean Salinity (SMOS-CATDS and ...
Tópico(s): Irrigation Practices and Water Management
2023 - Elsevier BV | Remote Sensing Applications Society and Environment
Produção Nacional
Cristiana Simão Seixas, Deborah Santos Prado, Carlos Alfredo Joly, Peter H. May, Estela Maria Souza Costa Neves, Leonardo Ribeiro Teixeira,
A governança ambiental é peça-chave para atingir a Agenda 2030 da Organização das Nações Unidas (ONU). Este artigo explora o potencial do Brasil de aproximar-se dos Objetivos do Desenvolvimento Sustentável (ODS) da Agenda 2030. Para tanto, apresenta seus avanços e retrocessos, em particular após a Constituição Federal de 1988 enfocando: licenciamento ambiental; vegetação nativa; recursos pesqueiros; recursos hídricos; unidades de conservação; e mudanças climáticas. Concluímos o artigo apontando que ...
Tópico(s): Environmental Sustainability and Education
2020 - FUNDAÇÃO GETÚLIO VARGAS | Cadernos Gestão Pública e Cidadania
Produção Nacional
Revisado por pares
Eliza Vitória Nascimento Figueredo, Estherfane Ribeiro de Lima, Alfredo Augusto Fernandes dos Santos, Dandara Dinna Cavalcante da Silva, Amauri dos Santos Araújo, Isabel Comasetto, Raíssa Rafaella Santos Moreno da Silva,
Objetivo: descrever como se caracteriza o envelhecimento da população do estado de Alagoas, a partir de uma metodologia de pesquisa de revisão bibliográfica sobre todos os artigos encontrados em relação ao envelhecimento da população idosa nas últimas décadas, utilizando as bases de dados Scientific Electronic Library Online (SciELO), PUBMED e dados coletados do Instituto Brasileiro de Geografia e Estatística- IBGE. Metodologia: Trata-se de um estudo descritivo, com delineamento transversal e abordagem ...
Tópico(s): Aging, Health, and Disability
2021 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
Produção Nacional
Revisado por pares
Felipe von Glehn, Sven Jarius, Rodrigo Pessoa Cavalcanti Lira, Maria Carolina Alves Ferreira, Fadua H Ribeiro von Glehn, Stella Castro, Guilherme C. Beltramini, Felipe PG. Bergo, Alessandro S. Farias, Carlos Otávio Brandão, Brigitte Wildemann, Alfredo Damasceno, Fernando Cendes, Leonilda Maria Barbosa dos Santos, Clarissa Lin Yasuda,
Background: Although aquaporin-4 (AQP4) is widely expressed in the human brain cortex, lesions are rare in neuromyelitis optica (NMO) spectrum disorders (NMOSD). Recently, however, several studies have demonstrated occult structural brain atrophy in NMO. Objective: This study aims to investigate magnetic resonance imaging (MRI) patterns of gray matter (GM) and white matter (WM) abnormalities in patients with NMOSD and to assess the visual pathway integrity during disease duration correlation of the retinal ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2014 - SAGE Publishing | Multiple Sclerosis Journal
Produção Nacional
Revisado por pares
Kaline de Mello, Alice Dantas Brites, Clarice Borges-Matos, Paulo André Tavares, Jean Paul Metzger, Ricardo Ribeiro Rodrigues, Zenilda Ledo dos Santos, Carlos Alfredo Joly, Gerd Sparovek,
Abstract Natural ecosystems are under severe threat worldwide and environmental policies are essential to minimize present and future impacts on biodiversity, ecosystem services and climate change. The New Forest Act in Brazil is the main policy to protect native vegetation in private lands, which comprise 54% of the remaining Brazilian native vegetation. However, conflicts between environmental and agricultural concerns in its implementation demand for balanced solutions based on scientific evidence. ...
Tópico(s): Environmental Conservation and Management
2022 - Fundação de Amparo à Pesquisa do Estado de SP | Biota Neotropica
Produção Nacional
Revisado por pares
Daniel Basílio Zandonadi, Heitor Monteiro Duarte, Mirella Pupo Santos, Luís Alfredo dos Santos Prado, Rodrigo Lemes Martins, Emiliano Nicolas Calderón, Ana Carolina Almeida Fernandes, Quézia Souza Santos, Filipe Junior Gonçalves Nunes, Luiz Carlos Felisberto Ribeiro, Taís Nogueira Fernandes, Alexandre Castilho, Francisco de Assis Esteves,
Isoëtes L. is a genus of lycophytes widely distributed around the world, with many endemic species. In our work we document the first successful large scale ex situ cultivation of the threatened species from Brazilian Amazon Isoëtes cangae and Isoëtes serracarajensis, which are endemic of a lake and close ponds nearby, respectively. This study aimed to develop the ex situ cultivation methods of the species I. cangae and I. serracarajensis. The capacity of regrowth and to tolerate high soluble iron ...
Tópico(s): Growth and nutrition in plants
2020 - Elsevier BV | Aquatic Botany
Produção Nacional
Audrey Handyara Bicalho, Fabio Ribeiro do Santos, Daniele Cristina Moreira, Luís Paulo Oliveira, Amanda Souto Machado, Lucyana Conceição Farias, Alfredo Maurício Batista de Paula, André Luiz Sena Guimarães, Sérgio Henrique Sousa Santos,
Background: Malnutrition induced by dietary restriction produces several metabolic changes that affect body weight, the digestive system, and annex organs, including the liver. Malnutrition generates an inflammatory state and increases oxidative stress. The liver is one of the body vital organs, becoming necessary to analyze the impact of food supplementation on the repair of possible changes that may occur in this organ due to malnutrition. Aims: To evaluate the effects of a low-cost supplementation ...
Tópico(s): Vitamin C and Antioxidants Research
2021 - Bentham Science Publishers | Recent Patents on Food Nutrition & Agriculture
Produção Nacional
Revisado por pares
Raúl D. Santos, Sérgio Timerman, Andrei C. Spósito, Alfredo Halpern, Adriano Segal, Artur Beltrame Ribeiro, Artur Garrido, Charles Mady, Fábio Fernandes, Geraldo Lorenzi‐Filho, José Antônio Franchini Ramires, Maria Teresa Zanela, M Grinberg, Márcio C. Mancini,
Tópico(s): Healthcare Regulation
2002 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Miguel Del Campo, Ian M. L. Feitosa, Erlane Marques Ribeiro, Dafne Dain Gandelman Horovitz, André Luiz Santos Pessoa, Giovanny Vinícius Araújo de França, Alfredo García‐Alix, Maria Juliana R. Doriqui, Héctor Yuri Conti Wanderley, Maria V. T. Sanseverino, Joao Ivanildo Neri, João Monteiro de Pina Neto, Emerson Soares dos Santos, Islane Verçosa, Mirlene Cecília Soares Pinho Cernach, Paula Frassinetti Vasconcelos de Medeiros, Sáile Cavalcante Kerbage, André A. Silva, Vanessa van der Linden, Celina Maria Turchi Martelli, Marli Tenório Cordeiro, Rafael Dhália, Fernanda Sales Luiz Vianna, César G. Victora, Denise P. Cavalcanti, Lavínia Schüler‐Faccini,
In October 2015, Zika virus (ZIKV) outbreak the Brazilian Ministry of Health (MoH). In response, the Brazilian Society of Medical Genetics established a task force (SBGM‐ZETF) to study the phenotype of infants born with microcephaly due to ZIKV congenital infection and delineate the phenotypic spectrum of this newly recognized teratogen. This study was based on the clinical evaluation and neuroimaging of 83 infants born during the period from July, 2015 to March, 2016 and registered by the SBGM‐ZETF. ...
Tópico(s): Virology and Viral Diseases
2017 - Wiley | American Journal of Medical Genetics Part A
Produção Nacional
Revisado por pares
Paulo André Tavares, Alice Dantas Brites, Vinícius Guidotti, Paulo Guilherme Molin, Kaline de Mello, Zenilda Ledo dos Santos, Luís Fernando Guedes Pinto, Jean Paul Metzger, Ricardo Ribeiro Rodrigues, Carlos Alfredo Joly, Gerd Sparovek,
Native vegetation in private lands plays an important role in providing ecosystem services and safeguarding biodiversity worldwide. Legal protection rules of this vegetation are thus crucial. In Brazil, since 1934, there has been a requirement for landowners to preserve a percentage of their land covered with native vegetation, the Legal Reserve. However, the 1934 legislation applies only to arboreal vegetation, while the protection of savannahs and grasslands begins after 1965 and 1989. The reference ...
Tópico(s): Economic and Environmental Valuation
2021 - Elsevier BV | Environmental Science & Policy
Produção Nacional
Revisado por pares
Pedro Henrique Salomão Ganança, Alfredo P. Santos‐Jr, Ricardo Alexandre Kawashita Ribeiro, Lourival Baía de Vasconcelos Neto, Ivan Alves dos Santos Júnior, Daniel de Sousa Guedes, Rafael de Fraga,
Abstract Investigating non‐random assemblages emerging in response to environmental gradients is relevant to understand mechanisms and processes affecting biodiversity. Species may be filtered from fractions of environmental gradients that limit dispersal, survival or ontogenetic development, which ultimately leads to biotic complementarities among sites. Non‐random assemblages as a response to environmental filtering have been widely demonstrated in Amazonian forests, but are rarely assessed in ...
Tópico(s): Wildlife-Road Interactions and Conservation
2021 - Wiley | Austral Ecology