Produção Nacional
Revisado por pares
Paulo Sávio Angeiras de Góes, Nilcema Figueiredo, Jerlucia Cavalcanti das Neves, Fabiana Moura da Motta Silveira, José Felipe Riani Costa, Gilberto Alfredo Pucca, Maritza Sosa Rosales,
Este trabalho discorre a respeito da avaliação da atenção secundária no âmbito da vigilância em saúde. Estudo descritivo, de caráter avaliativo normativo. Para análise de desempenho, foram utilizados dados secundários, com base na série histórica da produção de procedimentos odontológicos realizados nos CEO implantados no país e registrados pelo SIA/SUS no ano de 2007, e dados primários, pela visita in loco de 10% dos serviços implantados, com uso de questionários dirigidos à equipe profissional ...
Tópico(s): Medical Malpractice and Liability Issues
2012 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Allan Motta Couto, Paulo Fernando Trugilho, Alfredo Napoli, José Tarcísio Lima, José Reinaldo Moreira da Silva, Thiago de Paula Protásio,
The objective of this study was to evaluate the effect of radial position and final carbonization temperature on the chemical, physical and mechanical properties of charcoal from wood of Corymbia and Eucalyptus.Three individuals of Corymbia citriodora and two natural hybrids of Eucalyptus urophylla (VM04 and MN463) were cut.One short piece was removed from each individual and it was mechanically processed, so that the samples were removed at three different radial positions for the determination ...
Tópico(s): Natural Fiber Reinforced Composites
2015 - Editora da Universidade de São Paulo | Scientia Forestalis
Produção Nacional
Revisado por pares
Raphael Jurca Gonçalves da Motta, Luciana Yamamoto Almeida, Kelly Rocio Vargas Villafuerte, Alfredo Ribeiro‐Silva, Jorge Esquiche León, Camila Tirapelli,
Abstract Background and Objective Some studies suggest that regulatory T cells (Tregs) have suppressive effects on inflammatory osteolysis. The aim of this study was to evaluate Treg immunomarkers in periodontitis‐affected tissues from patients with periodontitis and clinically healthy gingiva (control). Material and Methods The presence and distribution of positive cells for CD4, CD25 and FOXP3 (Treg immunomarkers) in periodontitis‐affected tissues (epithelium and lamina propria) of 30 patients (ten ...
Tópico(s): Oral Health Pathology and Treatment
2019 - Wiley | Journal of Periodontal Research
Produção Nacional
Revisado por pares
Julie Hendry, Glenn Jones, Umesh Mahantshetty, Gustavo R. Sarria, Neiro Waechter da Motta, Elena Fidarova, May Abdel‐Wahab, Rashmi Prasad, Alfredo Polo, Eduardo Zubizarreta,
To compare loco-regional (LR) control and adverse effects (AE) of external beam radiotherapy (EBRT) in combination with 2 different fractionation schedules of HDR brachytherapy (HDRBT) with or without chemotherapy (CT) in cervical cancer.
Tópico(s): Breast Cancer Treatment Studies
2017 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Produção Nacional
Revisado por pares
Thiago de Paula Protásio, Paulo Fernando Trugilho, Alfredo Napoli, Marcela Gomes da Silva, Allan Motta Couto,
The objective of this work was to evaluate the carbonization yield of babassu nutshell as affected by final temperature, as well as the energy losses involved in the process. Three layers constituting the babassu nut, that is, the epicarp, mesocarp and endocarp, were used together. The material was carbonized, considering the following final temperatures: 450, 550, 650, 750, and 850ºC. The following were evaluated: energy and charcoal yields, pyroligneous liquid, non-condensable gases, and fixed ...
Tópico(s): Thermochemical Biomass Conversion Processes
2014 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira
Luciano Baresi, Angelo Morzenti, Alfredo Motta, Matteo Rossi,
UML is a well-known and widely used design notation: it offers a rich set of modeling elements, but their behavior is often not properly defined. Many proposals have tried to provide UML with a formal semantics, but they often focus on a limited number of diagram types, and thus do not provide a viable solution for the actual verification of complex UML models. This paper addresses a significant and consistent set of UML diagrams, called MADES UML, and uses a metric temporal logic to ascribe a formal ...
Tópico(s): Advanced Software Engineering Methodologies
2012 - Association for Computing Machinery | ACM SIGSOFT Software Engineering Notes
Francesco Pappalardo, Alessandro Cincotti, Alfredo Motta, Marzio Pennisi,
Atherosclerosis, a pathology affecting arterial blood vessels, is one of most common diseases of the developed countries. We present studies on the increased atherosclerosis risk using an agent based model of atherogenesis that has been previously validated using clinical data. It is well known that the major risk in atherosclerosis is the persistent high level of low density lipoprotein (LDL) concentration. However, it is not known if short period of high LDL concentration can cause irreversible ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2009 - Springer Science+Business Media | Lecture notes in computer science
A. Hernández-Almada, Genly León, Juan Magaña, Miguel A. García-Aspeitia, V. Motta, Emmanuel N. Saridakis, Kuralay Yesmakhanova, Alfredo D. Millano,
We study the scenario of Kanadiakis horizon entropy cosmology which arises from the application of the gravity-thermodynamics conjecture using the Kaniadakis modified entropy. The resulting modified Friedmann equations contain extra terms that constitute an effective dark energy sector. We use data from Cosmic chronometers, Supernova Type Ia, HII galaxies, Strong lensing systems, and Baryon acoustic oscillations observations and we apply a Bayesian Markov Chain Monte Carlo analysis to construct ...
Tópico(s): Advanced Thermodynamics and Statistical Mechanics
2022 - Oxford University Press | Monthly Notices of the Royal Astronomical Society
Omar M. Salazar, Talgit Sandhu, Neiro Waechter da Motta, María Ángeles Pérez Escutia, Eduardo Lanzós-Gonzales, A Mouelle-Sone, Alfredo Moscol, Mayer Zaharia, Shamas Zaman,
To find the fastest and most effective/efficient method to economically deliver fractionated half-body irradiation (HBI) for widespread (WS), symptomatic, metastatic bone cancer.A Phase III trial with 3 HBI arms: (Arm A) Control (15 Gy/5 fractions/5 days); (Arm B) Hyperfractionation (HF) (8 Gy/2 fractions/1 day); (Arm C) Accelerated HF (12 Gy/4 fractions/2 days). Six countries randomized 156 patients (all with WS bone metastases): 51, 56, and 49 patients to Arms A, B, and C, respectively. There were 72 (46%) ...
Tópico(s): Advanced Radiotherapy Techniques
2001 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics
Carla Fornaro, Maria Piubeni, Valeria Tovazzi, Deborah Cosentini, Maria C. Gelmi, Gabriella Rota, Barbara Berta, Wilma Barucco, Eleonora Lombardi, Luisa Moles, Tiziana Faustini, Tiziana Fettolini, Paolo Carlo Motta, Vittorio Ferrari, Alfredo Berruti, Elisabetta Conti,
Port-a-cath (PAC) system is one of the most frequently employed venous accesses for administration of chemotherapy and supportive care. To prevent late complications, the latest guidelines recommend flushing/locking procedures every four weeks. In this retrospective study, we evaluate the frequencies of late complications with a eight-week flushing/locking procedure compared to the standard one. This study retrospectively compares the frequency of complications occurred using standard versus delayed ...
Tópico(s): Intravenous Infusion Technology and Safety
2018 - Wiley | European Journal of Cancer Care
Carlo Ghezzi, Valerio Panzica La Manna, Alfredo Motta, Giordano Tamburrelli,
Summary Modern software systems are increasingly built by integrating different services implemented by independent organizations and offered in an open service marketplace. In such environment, multiple providers may compete with each other by publishing services that provide the same functionality, and export the same interface, but differ in the offered QoS and in particular in the offered performance. Clients and service integrators may therefore dynamically select the most efficient services ...
Tópico(s): Software System Performance and Reliability
2014 - Wiley | Concurrency and Computation Practice and Experience
Luciano Baresi, Angelo Morzenti, Alfredo Motta, Matteo Rossi,
Tópico(s): Advanced Software Engineering Methodologies
2011 - Springer Science+Business Media | Lecture notes in computer science
Allan Motta Couto, Paulo Fernando Trugilho, Alfredo Napoli, José Tarcísio Lima, J. R. M. da Silva, Thiago de Paula Protásio,
Tópico(s): Lignin and Wood Chemistry
2015 - Editora da Universidade de São Paulo | Scientia Forestalis
Rebecca Pedersini, Carla Fornaro, Pierluigi di Mauro, Susanna Bianchi, Lucia Vassalli, Vito Amoroso, Maria C. Gelmi, Mara Ardine, Filippo Rodella, Deborah Cosentini, Alberto Dalla Volta, Antonella Turla, Michela Pierini, Paolo Carlo Motta, Elisa Conti, Edda Simoncini, Alfredo Berruti,
Abstract Background The DigniCap System is an effective scalp cooling device for the prevention of chemotherapy‐induced alopecia in early breast cancer patients. Aim This prospective study was designed to confirm the efficacy and tolerability of the device, to explore potential factors associated with its efficacy and to collect data on patient perceptions and satisfaction. Methods Between January 2016 and June 2018, 163 early breast cancer patients eligible for adjuvant chemotherapy were enrolled. ...
Tópico(s): Dermatologic Treatments and Research
2020 - Wiley | International Journal of Nursing Practice
Carlo Ghezzi, Alfredo Motta, Valerio Panzica La Manna, Giordano Tamburrelli,
Tópico(s): Business Process Modeling and Analysis
2010 - Springer Science+Business Media | Lecture notes in computer science
Produção Nacional
Revisado por pares
Raphael Jurca Gonçalves da Motta, Camila Tirapelli, Roberto Juns da Silva, Kelly Rocio Vargas Villafuerte, Luciana Yamamoto Almeida, Alfredo Ribeiro‐Silva, Jorge Esquiche León,
Background: Dendritic cells (DCs) form a key link between innate and adaptive immune responses. The aim of this study is to analyze presence and distribution of immature (im) and mature (m) DCs in gingival tissue samples obtained from patients diagnosed with aggressive periodontitis (AgP), chronic periodontitis (CP), and clinically healthy periodontium (control group). Methods: Gingival tissue samples obtained from patients with: 1) AgP (aged <35 years); 2) CP (aged ≥35 years); and 3) control group (aged >18 ...
Tópico(s): Immune Response and Inflammation
2016 - Wiley | Journal of Periodontology
Pasquale Ambrosino, Paolo Parrella, Roberto Formisano, Antimo Papa, Giorgio Alfredo Spedicato, Matteo Nicola Dario Di Minno, Andréa Motta, Mauro Maniscalco,
Background Nasal nitric oxide (nNO) is considered a biomarker of nasal inflammation. Objective To perform a systematic review with meta-analysis and meta-regressions on the association between nNO levels and allergic rhinitis (AR). Methods PubMed, Web of Science, Scopus, and EMBASE databases were systematically searched. Differences between cases and controls were expressed as standardized mean differences (SMD) with 95% confidence intervals (CI). Results Overall, 39 articles were included: 30 containing ...
Tópico(s): Respiratory and Cough-Related Research
2020 - Elsevier BV | Annals of Allergy Asthma & Immunology
Luciano Baresi, Gundula Blohm, Dimitrios S. Kolovos, Nicholas Matragkas, Alfredo Motta, Richard F. Paige, Alek Radjenovic, Matteo Rossi,
Formal verification and validation activities from the early development phases can foster system consistency, correctness, and integrity, but they are often hard to carry out as most designers do not have the necessary background. To address this difficulty, a possible approach is to allow engineers to continue using familiar notations and tools, while verification and validation are performed on demand, automatically, and transparently. In this paper we describe how the problem of making formal ...
Tópico(s): Software Testing and Debugging Techniques
2013 - Springer Science+Business Media | Software & Systems Modeling
Pasquale Ambrosino, Mariasofia Accardo, Marco Mosella, Antimo Papa, Salvatore Fuschillo, Giorgio Alfredo Spedicato, Andréa Motta, Mauro Maniscalco,
Background. Chronic cough is a disabling condition with a high proportion of diagnostic and therapeutic failures. Fractional exhaled nitric oxide (FeNO) has been considered a useful biomarker for predicting inhaled corticosteroids (ICS) response. We evaluated the relationship between FeNO and ICS response in chronic cough by performing a systematic review with meta-analysis.Methods. PubMed, Web of Science, Scopus and EMBASE databases were systematically searched. Differences were expressed as Odds ...
Tópico(s): Voice and Speech Disorders
2021 - Informa | Annals of Medicine
Produção Nacional
Revisado por pares
Giovani Antônio Rodrigues, NP Qualio, LD de Macedo, LMAR Innocentini, Alfredo Ribeiro‐Silva, NT Foss, Marco Andrey Cipriani Frade, Ana Carolina Fragoso Motta,
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy established by the World Health Organization in 1982 and, despite its widespread use, Brazil ranks second worldwide in numbers of cases. Oral involvement in leprosy has been poorly described in the literature, and few studies have shown that although the bacillus is found in mucosa, specific leprosy lesions are rare ...
Tópico(s): Oral Health Pathology and Treatment
2016 - Wiley | Oral Diseases
Produção Nacional
Revisado por pares
Philippe Caufour, M.C.A Motta, A.M.Y Yamamura, Susana Vázquez, I I Ferreira, Alfredo V. Jabor, Myrna C. Bonaldo, M.S. Freire, Ricardo Galler,
Chimeric yellow fever (YF)-dengue type 2 (Den 2) viruses were constructed by replacing the premembrane (prM) and envelope (E) genes of YF 17D virus with those from Den 2 virus strains of south-east Asian genotype. Whereas viable chimeric viruses were successfully recovered when the YF 17D C gene and the Den 2 prM gene were fused at the signalase cleavage site, no virus could be rescued from the constructions fused at the viral protease cleavage site. Unlike YF virus that replicated in all the cell lines ...
Tópico(s): Viral Infections and Outbreaks Research
2001 - Elsevier BV | Virus Research
Pasquale Ambrosino, Salvatore Fuschillo, Mariasofia Accardo, Marco Mosella, Antonio Molino, Giorgio Alfredo Spedicato, Andréa Motta, Mauro Maniscalco,
The use of fractional exhaled nitric oxide (FeNO) has been proposed for identifying and monitoring eosinophilic airway inflammation in chronic obstructive pulmonary disease (COPD). To explore the clinical utility of FeNO in COPD, we aimed to assess its short-term variability in a clinically stable COPD cohort.
Tópico(s): Respiratory Support and Mechanisms
2022 - Multidisciplinary Digital Publishing Institute | Journal of Personalized Medicine
Pasquale Ambrosino, Stefano Sanduzzi Zamparelli, Marco Mosella, Roberto Formisano, Antonio Molino, Giorgio Alfredo Spedicato, Antimo Papa, Andréa Motta, Matteo Nicola Dario Di Minno, Mauro Maniscalco,
Endothelial dysfunction has been proposed to play a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow-mediated dilation (FMD) is recognized as an accurate clinical method to assess endothelial function. Thus, we performed a meta-analysis of the studies evaluating FMD in convalescent COVID-19 patients and controls with no history of COVID-19.A systematic literature search was conducted in the main scientific databases according to the Preferred Reporting ...
Tópico(s): Cardiovascular Disease and Adiposity
2022 - Informa | Annals of Medicine
Pasquale Ambrosino, Antonio Molino, Ilenia Calcaterra, Roberto Formisano, Silvia Stufano, Giorgio Alfredo Spedicato, Andréa Motta, Antimo Papa, Matteo Nicola Dario Di Minno, Mauro Maniscalco,
Background: Growing evidence points to a key role of endothelial dysfunction in the pathogenesis of COVID-19. In this study, we evaluated changes in endothelium-dependent flow-mediated dilation (FMD) in a cohort of convalescent COVID-19 patients undergoing pulmonary rehabilitation (PR). Methods: After swab test negativization, convalescent COVID-19 patients referring to a post-acute care facility for PR were consecutively screened for inclusion. Study procedures were performed at the time of hospitalization ...
Tópico(s): Heart Rate Variability and Autonomic Control
2021 - Multidisciplinary Digital Publishing Institute | Biomedicines
Pasquale Ambrosino, Ilenia Calcaterra, Antonio Molino, Pasquale Moretta, Roberta Lupoli, Giorgio Alfredo Spedicato, Antimo Papa, Andréa Motta, Mauro Maniscalco, Matteo Nicola Dario Di Minno,
Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated dilation (FMD) among convalescent COVID-19 patients. Methods: COVID-19 patients referred to a Pulmonary Rehabilitation Unit within 2 months from swab test negativization were consecutively evaluated for inclusion and compared to controls matched for age, gender, ...
Tópico(s): Climate Change and Health Impacts
2021 - Multidisciplinary Digital Publishing Institute | Biomedicines
Produção Nacional
Revisado por pares
Yasmin Yamanaka, Maurício Eiji de Almeida Santos Yamashita, Lara Maria Alencar Ramos Innocentini, Leandro Dorigan de Macedo, Fernando Chahud, Alfredo Ribeiro‐Silva, Ana Maria Ferreira Roselino, Maria José Alves Rocha, Ana Carolina Fragoso Motta,
A great number of lichenoid lesions have overlapping clinicopathological features, so the use of adjunct tests to establish definitive diagnosis is recommended for correct management and prognosis of the lesions. In this context, direct immunofluorescence (DIF) can be a useful tool. Thus, this study aimed to characterize the clinical, histopathological, and DIF pattern in patients with oral lichen planus (OLP) and patients with oral lichenoid lesions (OLLs). Patients with OLP and patients with OLL ...
Tópico(s): Oral and Maxillofacial Pathology
2017 - Lippincott Williams & Wilkins | American Journal of Dermatopathology
Gaetano Corso, E. Trivellone, Andréa Motta, Alfredo Postiglione, Francesco Paolo Mancini, Virginia Carbone, Claudio Napoli,
Oxidation of low density lipoprotein (LDL) has been implicated in atherogenesis. An increased content of oleic acid in LDL and the substitution of monounsaturated for polyunsaturated fatty acids in the diet reduce LDL oxidation. With 1H-NMR analysis, all LDL modifications, including the production of copper-induced aldehyde products, can be evaluated simultaneously. The aim of the present study was to investigate whether the fatty acid composition of LDL affected the NMR evaluation of aldehyde compounds. ...
Tópico(s): Fatty Acid Research and Health
1997 - Elsevier BV | Clinica Chimica Acta
Produção Nacional
Revisado por pares
Allan Motta Couto, Thiago Campos Monteiro, Paulo Fernando Trugilho, José Tarcísio Lima, José Reinaldo Moreira da Silva, Alfredo Napoli, Diego Pierre de Almeida,
Tópico(s): Bamboo properties and applications
2022 - Springer Science+Business Media | Journal of Forestry Research
Produção Nacional
Revisado por pares
Ying‐Qian Mo, Hiroyuki Nakamura, Tsutomu Tanaka, Toshio Odani, Paola Pérez, Youngmi Ji, Benjamin N. French, Thomas Pranzatelli, Drew G. Michael, Hongen Yin, Susan S. Chow, Maryam Khalaj, Sandra Afione, Changyu Zheng, Fabíola Reis de Oliveira, Ana Carolina Fragoso Motta, Alfredo Ribeiro‐Silva, Eduardo Melani Rocha, Cuong Q. Nguyen, Masayuki Noguchi, Tatsuya Atsumi, Blake M. Warner, John A. Chiorini,
BMP6 is a central cytokine in the induction of Sjögren's syndrome–associated (SS-associated) secretory hypofunction. However, the upstream initiation leading to the production of this cytokine in SS is unknown. In this study, RNA ISH on salivary gland sections taken from patients with SS indicated monocytic lineage cells as a cellular source of BMP6. RNA-Seq data on human salivary glands suggested that TLR4 signaling was an upstream regulator of BMP6, which was confirmed by in vitro cell assays and ...
Tópico(s): Lymphatic System and Diseases
2022 - American Society for Clinical Investigation | Journal of Clinical Investigation
Produção Nacional
Revisado por pares
Ricardo Galler, Renato Sérgio Marchevsky, Elena Caride, L.F.C. Almeida, A.M.Y. Yamamura, Alfredo V. Jabor, Mario Motta, Myrna C. Bonaldo, Evandro Silva Freire Coutinho, M.S. Freire,
A chimeric yellow fever (YF)-dengue serotype 2 (dengue 2) virus was constructed by replacing the premembrane and envelope genes of the YF 17D virus with those from dengue 2 virus strains of Southeast Asian genotype. The virus grew to high titers in Vero cells and, after passage 2, was used for immunogenicity and attenuation studies in rhesus monkeys. Subcutaneous immunization of naive rhesus monkeys with the 17D-D2 chimeric virus induced a neutralizing antibody response associated with the protection ...
Tópico(s): Viral Infections and Outbreaks Research
2005 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research