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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Joseph A. Lewnard, Marina Antillón, Gregg Gonsalves, Alice Miller, Albert I. Ko, Virginia E. Pitzer,

Introduction of Vibrio cholerae to Haiti during the deployment of United Nations (UN) peacekeepers in 2010 resulted in one of the largest cholera epidemics of the modern era. Following the outbreak, a UN-commissioned independent panel recommended three pre-deployment intervention strategies to minimize the risk of cholera introduction in future peacekeeping operations: screening for V. cholerae carriage, administering prophylactic antimicrobial chemotherapies, or immunizing with oral cholera vaccines. ...

Tópico(s): COVID-19 epidemiological studies

2016 - Public Library of Science | PLoS Medicine

Artigo Revisado por pares

Allison J. Gonsalves, Jrène Rahm, Alice Teles de Carvalho,

Abstract Grounded in sociocultural theory, this study explores how the figured world of science is reworked through a series of multi‐media activities that were introduced into a girls‐only conversation club in an after school program for Teens. The study is part of a multi‐sited ethnography in which we explored youths' engagement with science within three sites. In this paper, we focus on a qualitative case study of one site. We present an analysis of the kinds of resources and cultural models ...

Tópico(s): Environmental Education and Sustainability

2013 - Wiley | Journal of Research in Science Teaching

Artigo Acesso aberto Revisado por pares

Patrick Mellors, Surendra Dasari, Mindy Kohlhagen, Taxiarchis Kourelis, Ronald S. Go, Eli Muchtar, Morie A. Gertz, Shaji Kumar, Francis K. Buadi, Maria Alice V. Willrich, John A. Lust, Prashant Kapoor, Martha Q. Lacy, David Dingli, Yi L. Hwa, Amie Fonder, Miriam Hobbs, S. R. Hayman, Rahma Warsame, Nelson Leung, Yi Lin, Wilson I. Gonsalves, Mustaqeem Siddiqui, Robert A. Kyle, S. Vincent Rajkumar, David Murray, Angela Dispenzieri,

Immunoenrichment-based matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), termed MASS-FIX, offers several advantages over immunofixation for the detection and isotyping of serum monoclonal protein, including superior sensitivity and specificity, the ability to differentiate therapeutic monoclonal antibodies, and the rapid identification of light chain (LC) N-glycosylation. We identified 6315 patients with MASS-FIX performed at our institution since 2018. Of ...

Tópico(s): Glycosylation and Glycoproteins Research

2021 - Springer Nature | Blood Cancer Journal

Artigo Acesso aberto Brasil Produção Nacional

Manoel Teixeira Souza, Osmar Nickel, Dennis Gonsalves,

Versoes traduziveis e nao traduziveis do gene da capa proteica (cp) de um isolado de Papaya ringspot virus (PRSV) coletado no Estado da Bahia, Brasil, foram produzidas para expressao nas variedades Sunrise e Sunset Solo de mamoeiro (Carica papaya). O sistema de biobalistica foi utilizado para transformar embrioes somaticos secundarios derivados de embrioes zigoticos imaturos. Cinquenta e quatro linhas transgenicas, sendo 26 contendo versoes traduziveis e 28 contendo versoes nao traduziveis do gene ...

Tópico(s): Insect Resistance and Genetics

2005 - Springer Nature | Fitopatologia Brasileira

Artigo Acesso aberto Revisado por pares

Isabel Lu, Karla L. Hanson, Stephanie Jilcott Pitts, Jane Kolodinsky, Alice S. Ammerman, Marilyn Sitaker, Weiwei Wang, Leah C. Volpe, Emily H. Belarmino, Jennifer Garner, Liana Gonsalves, Rebecca A. Seguin,

Abstract Objective: To examine participants’ experiences with nutrition education classes that were implemented with and designed to complement a cost-offset community-supported agriculture (CSA) programme. Design: Qualitative analysis of data from twenty-eight focus groups with ninety-six participants enrolled in Farm Fresh Foods for Healthy Kids (F3HK). Transcribed data were coded and analysed by a priori and emergent themes. Setting: Rural and micropolitan communities in New York, North Carolina, ...

Tópico(s): Child Nutrition and Feeding Issues

2020 - Cambridge University Press | Public Health Nutrition

Artigo Acesso aberto Revisado por pares

Eneyi E. Kpokiri, Dan Wu, Megan L. Srinivas, Juliana Anderson, Lale Say, Osmo Kontula, Noor Ani Ahmad, Chelsea Morroni, Chimaraoke Izugbara, Richard de Visser, Georgina Yaa Oduro, Evelyn Gitau, Alice Welbourn, Michele P. Andrasik, Wendy V. Norman, Soazig Clifton, Amanda Gabster, Amanda N. Gesselman, Chantal Smith, Nicole Prause, Adesola Olumide, Jennifer Toller Erausquin, Peter Muriuki, Ariane van der Straten, Martha Nicholson, Kathryn A. O’Connell, Meggie Mwoka, Nathalie Bajos, Catherine H Mercer, Lianne Gonsalves, Joseph D. Tucker,

Population health surveys are rarely comprehensive in addressing sexual health, and population-representative surveys often lack standardised measures for collecting comparable data across countries. We present a sexual health survey instrument and implementation considerations for population-level sexual health research. The brief, comprehensive sexual health survey and consensus statement was developed via a multi-step process (an open call, a hackathon, and a modified Delphi process). The survey ...

Tópico(s): Mobile Health and mHealth Applications

2021 - BMJ | Sexually Transmitted Infections

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Alice Miranda Bezerra Medeiros, Mariana Gama e Silva, Jackson de Menezes Barbosa, Érica Martins de Lavor, Tiago Feitosa Ribeiro, Cícero André Ferreira Macêdo, Luiz Antonio Miranda de Souza Duarte Filho, Thiala Alves Feitosa, Jussara de Jesus Silva, Harold Hilarion Fokoue, Cleônia Roberta Melo Araújo, Arlan de Assis Gonsalves, Luciano Augusto de Araújo Ribeiro, Jackson Roberto Guedes da Silva Almeida,

Pain and inflammation are unpleasant experiences that usually occur as a result of tissue damage. Despite the number of existing analgesic drugs, side effects limit their use, stimulating the search for new therapeutic agents. In this sense, five hydrazone derivatives (H1, H2, H3, H4, and H5), with general structure R 1 R 2 C = NNR 3 R 4 , were synthesized with molecular modification strategies. In this paper, we describe the ability of hydrazone derivatives to attenuate nociceptive behavior and the ...

Tópico(s): Phenothiazines and Benzothiazines Synthesis and Activities

2021 - Public Library of Science | PLoS ONE

Artigo Revisado por pares

Alice Barratt, Leroy Gonsalves, Christopher Turbill,

Abstract Small insectivorous bats often enter a state of torpor, a controlled, reversible decrease in body temperature and metabolic rate. Torpor provides substantial energy savings and is used more extensively during periods of low temperature and reduced prey availability. We studied torpor use and activity of a small (10.1 ± 0.4 g) fishing bat, Myotis macropus, during winter in a mild climate in Australia. We predicted that the thermal stability of water would make foraging opportunities in winter ...

Tópico(s): Effects of Environmental Stressors on Livestock

2022 - Oxford University Press | Journal of Mammalogy

Revisão Brasil Produção Nacional Revisado por pares

Nayara Matos Pereira, Luiz Alves Vieira Netto, Luís Felipe Araújo Peres, Alice Jardim Zaccariotti, Lígia Gonsalves Ribeiro, Paulo Ronaldo Jubé Ribeiro,

Tópico(s): Neurosurgical Procedures and Complications

2021 - Springer Science+Business Media | Child s Nervous System

Artigo Acesso aberto Brasil Produção Nacional

Manoel Teixeira Souza, Osmar Nickel, Dennis Gonsalves,

Translatable and nontranslatable versions of the coat protein (cp) gene of a Papaya ringspot virus (PRSV) isolate collected in the state of Bahia, Brazil, were engineered for expression in Sunrise and Sunset Solo varieties of papaya (Carica papaya). The biolistic system was used to transform secondary somatic embryo cultures derived from immature zygotic embryos. Fifty-four transgenic lines, 26 translatable and 28 nontranslatable gene versions, were regenerated, with a transformation efficiency of ...

Tópico(s): Transgenic Plants and Applications

2005 - Springer Nature | Fitopatologia Brasileira

Artigo Acesso aberto Revisado por pares

Thomas J. Coates, Agnès Fiamma, Greg Szekeres, Shari L. Dworkin, Robert H. Remien, Brent W Hanson, Jean-Baptiste Rudatsikira,

... their programmes more accountable to the public. Gregg Gonsalves' talk at the International AIDS Society meetings in ... for Family Health (SFH) Cal Bruns, Mat©hbox Alice Brown, JD, Ford Foundation, South Africa; Council on ...

Tópico(s): HIV/AIDS Impact and Responses

2007 - Lippincott Williams & Wilkins | AIDS

Artigo Acesso aberto Revisado por pares

Patrick Mellors, Surendra Dasari, Mindy Kohlhagen, Bonnie K. Arendt, Morie A. Gertz, Shaji Kumar, Francis K. Buadi, Maria Alice V. Willrich, John A. Lust, Prashant Kapoor, Martha Q. Lacy, David Dingli, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Suzanne R. Hayman, Taxiarchis Kourelis, Rahma Warsame, Eli Muchtar, Nelson Leung, Ronald S. Go, Yi Lin, Wilson I. Gonsalves, Mustaqeem Siddiqui, Robert A. Kyle, S. Vincent Rajkumar, David Murray, Angela Dispenzieri,

Introduction: Since 2018, immunoenrichment-based matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), termed MASS-FIX, has replaced immunofixation for the detection and isotyping of serum monoclonal proteins at Mayo Clinic. MASS-FIX has advantages including increased sensitivity, specificity, and the ability to distinguish therapeutic monoclonal antibodies. Herein, we report the laboratory characteristics and distribution of diagnoses of patients tested clinically ...

Tópico(s): Hemoglobinopathies and Related Disorders

2020 - Elsevier BV | Blood

Artigo Acesso aberto Revisado por pares

Joan Shang, Diane M. Del Valle, Graham J. Britton, K Mead, Urvija Rajpal, Alice Chen-Liaw, Ilaria Mogno, Z Li, Rajita Menon, Edgar Gonzalez‐Kozlova, Arielle Elkrief, Jonathan U. Peled, Tina Ruth Gonsalves, Neil J. Shah, Michael A. Postow, Jean‐Frédéric Colombel, Sacha Gnjatic, David Faleck, Jeremiah J. Faith,

Immunotherapy-related colitis (irC) frequently emerges as an immune-related adverse event during immune checkpoint inhibitor therapy and is presumably influenced by the gut microbiota. We longitudinally studied microbiomes from 38 ICI-treated cancer patients. We compared 13 ICI-treated subjects who developed irC against 25 ICI-treated subjects who remained irC-free, along with a validation cohort. Leveraging a preclinical mouse model, predisease stools from irC subjects induced greater colitigenicity ...

Tópico(s): Clostridium difficile and Clostridium perfringens research

2024 - Rockefeller University Press | The Journal of Experimental Medicine

Artigo

Kristen Carson, Sarah Bundrick Grimes, Jacqueline M. McGinley, Media Thornton, John P. Mulhall, A. Bourke, Connail McCrory, Brian Marsh, R. Hone, Dermot Phelan, Matthew J. White, J. Fabry, Declan Hughes, Kristen Carson, Martin J. Donnelly, E. M. Shanahan, G. Fitzpatrick, M. Bourke, D. Warde, Donal J. Buggy, Nicola Hughes, Anna M. Taylor, Nathan Dowd, Todd E. Markham, W. Blunnie, Geoffrey C. Nicholson, Erin O’Leary, A. J. Cunningham, Robyn Dwyer, S. R. McMechan, C. Cullen, G. Dempsey, Galen E.B. Wright, Gilbert MacKenzie, J. Anderson, J. Adgey, Michael Walsh, Patrick O’Callaghan, Iain Graham, J. A. O’Hare, Martin Geoghegan, Nurul Iman, Purvi Shah, Rakesh Chander, F. Lavin, Kieran Daly, P. W. Johnston, Zuhratul Imam, A.A.J. Adgey, R. A. Rusk, Sue Richardson, Albert B. Hale, B. M. Kinsella, Garret A. FitzGerald, Gerald King, P. Crean, G. Gearty, T. Cawley, James R. Docherty, James Geraghty, H. Osborne, Julia Upton, Grace D’Arcy, J. Stinson, T Cooke, Mary Paula Colgan, C. Michael Hall, Jeanne Tyrrell, Karl Gaffney, M. C. Grouden, D. J. Moore, Gregor D. Shanik, J. Feely, N Delanty, M. Reilly, J. A. Lawson, Des Fitzgerald, Marie Reilly, Brendan McAdam, Christi Bergin, M. J. Walshe, Niall A. Herity, J. D. Allen, Bernard Silke, Harsh Singh, Shane O’Neill, M. Hargrove, Elizabeth Coleman, Elizabeth Shorten, Thomas Aherne, B E Kelly, David Hill, E. McIlrath, Barbara Morrow, Gavin Lavery, Bronagh Blackwood, J. P. H. Fee, L. G. Kevin, Marianne Doran, David J Tansey, Isabel Boylan, A. J. McShane, Gerard O’Reilly, Brendan Tuohy, P.B. Grainger, T. Larkin, J. Mahady, J. F. Malone, Carol Condon, Tom Donoghue, J. Patrick O’Leary, Jane Lyons, Y. K. Tay, S. N. Tham, Haoyue Tan, G. Gibson, A O’Grady, M. Leader, J. J. Walshe, M. Carmody, J. Donohoe, Gillian Murphy, William T. O’Connor, L. Barnes, R. G. P. Watson, C. Darby, R. R. O’Moore, F Mulcahy, E. O’Toole, D. S. O’Briain, Megann Young, D.A. Buckley, E. Healy, S. Rogers, N. Ni Scannlain, Malachi J. McKenna, Y. McBrinn, B. Murray, R. Freaney, Edward J. Barrett, Q. Razza, F. Abuaisha, David Powell, Timothy M. Murray, Arthur Powell, E. O’Mongain, John O’Neill, R. P. Kernan, Pat O’Connor, D. Clarke, Ursula Fearon, S. K. Cunningham, T. J. McKenna, Frances J. Hayes, Andrew Heffernan, Kieran Sheahan, Robert A. Harper, G. D. Johnston, A. B. Atkinson, B. Sheridan, P. M. Bell, Anthony P. Heaney, G. L. Loughrey, D. R. McCance, D. R. Hadden, A. L. Kennedy, Paul E. McNamara, C. O’Shaughnessy, Helen Loughrey, I. M. Reid, Seamus Teahan, Matthew D. Caldwell, T. N. Walsh, Jared McSweeney, T. P. J. Hennessy, M. T. P. Caldwell, Paul Byrne, T. P. J. Hennessy, A. A. El-Magbri, F. M. Stevens, Richard O’Sullivan, C. F. McCarthy, J. Laundon, M. A. Heneghan, M. Kearns, J. M. R. Goulding, E. L. Egan, Barrie McMahon, Fran Hegarty, J. F. Malone, Raphael B. Merriman, Padraic MacMathúna, John Crowe, J. Lennon, Paul D. White, Eric Clarke, M. C. Prabhakar, E. Ryan, D. C. Graham, Phillip Yeoh, Philip A. Kelly, Donogh McKeogh, Conor O’Keane, A. Kitching, E. Mulligan, T. F. Gorey, N. Mahmud, M. O’Connell, Michael Goggins, P. W. N. Keeling, D. G. Weir, D K Kelleher, G. S. A. McDonald, D. Maguire, G. O’Sullivan, Brian J. Harvey, Abhisar V. Cherukuri, Jason McGrath, Conrad Timon, P. Lawlor, J.Conor O’Shea, Mitchell S. Buckley, Laural English, Timothy Walsh, Colm OʼMorain, S. M. Lavelle, B. Kanagaratnam, B. Harding, Barbara A. Murphy, James F. Kavanagh, Derek Kerr, Ellen Lavelle, T. O’Gorman, S. Liston, Chris Fitzpatrick, Patricia Fitzpatrick, Michael J. Turner, Alana Murphy, Dorothy Cafferty, John P. Dowling, Gerard Bury, S. K. Al-Ghazal, Eric Zimmermann, John O’Donoghue, J. McCann, Carol Sheehan, Laure Boissel, Maureen E. Lynch, B. Cryan, Séamus Fanning, D. O’Meara, Janna Fennell, Peter Byrne, D. Lyons, Ríona Mulcahy, A. Pooransingh, J. B. Walsh, D. Coakley, Desmond O’Neill, Nicola Ryall, Patrick Connolly, R. Namushi, Mark Lawler, Anna Locasciulli, Almalina Bacigalupo, Peter Humphries, Shaun R. McCann, Derwood Pamphilon, Mary Reidy, Michael Madden, Thomas Finch, M. Borton, Cameron Barnes, S. Lawlor, N. Gardiner, Lorraine Egan, A. Orren, Julie Doherty, Catherine Curran, Deirdre O’Hanlon, P. Kent, Michael J. Kerin, Dermot Maher, H. F. Given, S. Lynch, R. McManus, Cliona OʼFarrelly, L. Madrigal, C. Feighery, Diarmuid P. O’Donoghue, Ciara Whelan, Irene Maeve Rea, Moira Stewart, P. Campbell, H. D. Alexander, A. D. Crockard,

Pre-operative stress is well documented and multifactorial in aetiology.Anxious patients often show further signs of stress immediately prior to indaction of anaesthesia and during pre-oxygenation.In our hospital standard black rubber masks are used for preoxygenation.Several authors have reported the use of scented oils painted onto the rubber face masks facilitating inhalationalinduction in children 1.The objective of this study was to assess whether adult patients had a preference for the type ...

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