Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Lesley Garrett, Colin Drury, Graham Adams, Barbara Hall, Aa Gill, Catherine Hayward, Geoffrey Barlow, Simon Wllde, Fred Redwood, Helen Kirwan-Taylor, Philip Norman, Goldfrey Smith, Helen Davies, James Clark, A Jenkins, Jeffrey Bennett, Rob Hughes, John Peter, V S, Emma Moore, Amanda Ursell, Robert Waites, Dave Bishop, Jonathan Miller, Sue Chester, Allcia Wyllie, Sir David Ford Chairman, Jane Mulkerrins, J D, Edward Woodward, Frank Whitford, Ivo Tennant, Nicolette Jones, Nicola Venning, Kathryn Cooper, David Smith, Gordon Massey, Joanna Copley, Tim Richards, Rory Godson, Fai Lee, Melanie Phillips, E P, Patrick McCarthy Chairman and Editorial Director, Andrew Sullivan, Clive Davis, Guy Dennis, Frank WHITFORD's, Kathy Brewis, Joseph Dunn, Tony Allen-Mills, Martin James, Tristram Hunt, Anthony Sattin, Alison Brace, Irwin Stelzer, Robert Hewison, Peter Wilson, Rosie Millard, David Dougill, Nicholas Hellen Social Affairs Editor, Warren Shore, P K Atkinson, Dan Caims, Heather Ashton Emeritus Professor of Clinical Psychopharmacology, Phil Baty, Philip Kingsley, Louise Weston, Geraldine Hackett, Jermy Clarkson, David Hewson, John Swain, Joe Nicol, Hugh Canning, Margarette Driscoll, Geraldine Hackett Education Correspondent, Jeremy Clarkson, Graham Duffill, Edward Porter, Peter Conradi, Stewart Lee, Louise Taylor, Victoria Segal, Flic Everett, Max Anderson, Jane Renton, Hugh McIlvannney, James Clark Defence Correspondent, Eben Black, Lawrence Sutton, Cheryl Markosky, Sandra Bennett Director, Nick Caln, Alan Millard, Lavenham, George Perry, Adam Nathan, Nick Gardner, Sir Richard Branson, Jonathan Margolis, Stefan Holter, Peter Seymour, Stuart Wavell, Christopher Silvester, Richard Goss, Paul Donovan, Alastair Hendy, Richard Lamping, Vincent Crump, Clive Jacobs, Simon Mills, Kirstic Hamilton, Lucinda Kemeny, Jasper Gerard, Paul Driver, Simon Fanshawe, John Humphrys, Ann McFerran, Nicholas Hellen, Richard Brooks, Danny Sanziger, Ian Hawkey, Joe Lovejoy football correspondent, Shelley Von Strunckel, Christopher Morgan, David Leppard, Stephen Todd, Paul Durman, Victoria O'Brian, David Meredith, Alicia Wyllie, Mark Edwards, Kirstie Hamilton, Neil Hynd, Gordon Thorpe, Susan Clark, Eben Black Chief Political Correspondent, Gally Law, Peter Hoare, Maria Laura, Marilyn Cox, Victoria O'Brien, Alan Combes, Raymond Keene, Josh Townsend, David Cracknell, Cosmo Landesman, Marie Colvin, Andy Knott, Stephen Jones, Barry Flatman, Uzi Mahnaimi, Richard Evans, Nick Cain, Michael Wright, Judith Prescott, Peta Bee, Kate Rew, Caroline Donald, Sir Edward Heath, Rob Ryan, David Walsh, Caroline Gascoigne, Jack Grimston, Colin McDowell, Stephen Armstrong, John Elliott, Ron Clarke, Michael Sheridan Far East Correspondent, Roland White, Jenifer Edger, Mark Bolland, Garth Alexander, Rachel Cooke, Maurice Chittenden, Richard Brooks Arts Editor, Richard Rae, Ray Hutton, Frank Fitzgibbon, Martin Ivens, Huw Richards, Bupa's Fergus Kee, Michael Sheridan, John Harlow, David Green, John Waples, A A Gill, Ros Dodd, Miranda Seymour's, Matthew Campbell, Brian Glanville, Martin Wroe, Louis Rogers, Ruth Lederman, Tom Robbins, Natalle Graham, Suffolk, Tony Benn, Stephen Pettitt, Mimmo Candido, Roland Jones, Sally Kinnes, Naomi Caine, Nigel Powell, David Wickers, Julian Nettlefold, Christine Ross, John Cornwell, Mark Hodson, Andrew Frankel, Graham Norwood, Christopher Higgins, Jonathan Futrell, Rupert Steiner, David Budworth, Hugh Pearman, Pete Oliver, Kevin Maguire, John Alzlewood, David Smith Economics Editor, Stephanie Clark, Graham Mackay, Simon Crerar, Hugh Bradley, Sarah Baxter, Paul Ham Sydney, Chris Feetenby, India Knight, Victoria Stanley, Steve Grant, Nicola Gill, Jeseph Dunn, Dan Pearson, Nick Faldo, Rosie Waterhouse, Richard Lewis, Boris Schapiro, Mike Pitts,
... Eureka! Scientific Milestones Picture Gallery Jacob's Creek Alizee Ford One L of a guy One L ...
2001 - Gale Group | Sunday Times HA GDA
Marie-Ève Côté, Marie‐Ève Boulay, Sophie Plante, Jamila Chakir, Louis‐Philippe Boulet, Hanan Ahmed, Maria-Beatriz Ospina, Kyriaki Sideri, Harissios Vliagoftis, Sara F. Johnson, Roberta L. Woodgate, Guilhem Cros, Pierre Teira, Sonia Cellot, Henrique Bittencourt, Hélène Decaluwe, Marie France Vachon, Michel Duval, Élie Haddad, Vy H.D. Kim, Anne Pham‐Huy, Eyal Grunebaum, John-Paul Oliveria, Stephanie Phan, Mark W. Tenn, Damian Tworek, Steven G. Smith, Adrian J. Baatjes, Caitlin Obminski, Caroline Munoz, Tara Scime, Roma Sehmi, Gail M. Gauvreau, Brittany Salter, Steven G. Smith, Caitlin Obminski, Caroline Munoz, Abbey Schlatman, Tara Scime, Rick Watson, Roya Sherkat, Razieh Khoshnevisan, Saba Sheikhbahaei, Stephen Betschel, Richard Warrington, R. Robert Schellenberg, Michael Fein, Jean-Philippe Pelletier, Manstein Kan, Roxane Labrosse, Raymond Mak, James Loh, Amin Kanani, Dominik Alex Nowak, Paul K. Keith, Daniel Pannozzo, Hermenio Lima, Diana Pham, Hoang Pham, Gonzalo G. Alvarez, Istvan T. Bencze, Krishna Sharma, Mark D. Smith, Shawn D. Aaron, Jennifer Block, Tara Keays, Judith A. Leech, David Schneidermen, Jodi Cameron, Jennifer Forgie, Alicia Ring, John W. O’Quinn, Stephanie Santucci, William H. Yang, Ena Gaudet, Shawn D. Aaron, Mathew Voisin, Rozita Borici‐Mazi, Kateryna Vostretsova, Donald Stark, Elizabeth Yeboah, Michelle Martin‐Rhee, Cheryl Gula, Clare Cheng, Geoff Paltser, Alizée Dery, Ann E. Clarke, Kari C. Nadeau, Laurie Harada, Kimberley Weatherall, Celia M.T. Greenwood, Denise Daley, Yuka Asai, Moshe Ben‐Shoshan, Ling Ling, Maria B. Ospina, Jennifer L. P. Protudjer, Mirja Vetander, Marianne van Hage, Ola Olén, Magnus Wickman, Anna Bergström, Timothy Teoh, Christopher P. Mill, Tiffany Wong, Ingrid Baerg, Angela Alexander, Kyla J. Hildebrand, John Mark Dean, Boris Kuzeljevic, Edmond S. Chan, Jonathan Argeny, Mia Gona-Hoepler, P. Fucik, Edith Nachbaur, Saskia Gruber, Reto Crameri, Andreas Glaser, Zsolt Szépfalusi, Claudio Rhyner, Thomas Eiwegger, Greg Plunkett, Brad Mire, Mehtap Yazıcıoğlu, Ceren Can, Gokce Ciplak, Victoria E. Cook, Élodie Portales-Casamar, Emil Nashi, Sofianne Gabrielli, Marie-Noël Primeau, Christine Lejtenyi, Elena Netchiporouk, Alizée Dery, Greg Shand, Erica Hoe, Joel Liem, Jason Kangeun Ko, David Huang, Jorge Mazza, Mary McHenry, Anthony Otley, Wade Watson, J. Kraft, Mihaela Paina, Ahmed A. Darwish Hassan, Delia Heroux, Lynn Crawford, Gail M. Gauvreau, Judah A. Denburg, Linda Pedder, Zave Chad, Gordon L. Sussman, Jacques Hébert, Charles W. Frankish, Timothy Olynych, Amarjit Cheema, Jaime Del Carpio, Rachel Harrison, Bahar Torabi, Elaine J. Medoff, Jennifer Mill, Jaclyn A. Quirt, Xia Wen, Jonathan Kim, Angel Jimenez Herrero, Harold L Kim, Magdalena J. Grzyb, Marie-Noël Primeau, Meghan B. Azad, Zihang Lu, Allan B. Becker, Padmaja Subbarao, Piush J. Mandhane, Stuart E. Turvey, Malcolm R. Sears, Anne‐Marie Boucher‐Lafleur, Valérie Gagné‐Ouellet, Éric Jacques, Catherine Laprise, Michael Chen, Toby K. McGovern, Mikael Adner, James G. Martin, Nela Cosic, Henry Ntanda, Gerald F. Giesbrecht, Anita L. Kozyrskyj, Nicole Létourneau, Bassel Dawod, Jean S. Marshall, Sarah De Schryver, Michelle Halbrich, Sébastien La Vieille, Harley Eisman, Reza Alizadehfar, Lawrence Joseph, Judy Morris, Laura Y. Feldman, Jesse D. Thacher, Inger Kull, Erik Melén, Göran Pershagen, Jennifer L. P. Protudjer, Ali Hosseini, Tillie‐Louise Hackett, Jeremy A. Hirota, Kelly M. McNagny, Susan J. Wilson, Chris Carlsten, Saiful Huq, Rishma Chooniedass, Brenda Gerwing, Henry Huang, Diana L. Lefebvre, Allan B. Becker, Mona M. Khamis, H. Awad, Kevin J. H. Allen, Darryl J. Adamko, Anas El‐Aneed, Young Woong Kim, Daniel Gliddon, Casey P. Shannon, Amrit Singh, Pascal Hickey, Anne K. Ellis, Helen Neighbour, Mark Larché, Scott J. Tebbutt, Erika Ladouceur, Moira Stewart, Josh Evans, Jeff Masuda, Teresa To, Malcolm King, Miriam Larouche, Liming Liang, Stephanie Legere, Ian D. Haidl, Jean‐François Légaré, Jean S. Marshall, Malcolm R. Sears, Theo J. Moraes, Félix Ratjen, Per Gustafsson, Wendy Lou, Michelle L. North, Elizabeth Lee, Vanessa Omana, Jenny Thiele, Jeff Brook, Tanvir Rahman, Duncan Lejtenyi, Ryan Fiter, Ciriaco A. Piccirillo, Bruce Mazer, Elinor Simons, Kyla J. Hildebrand, Stuart E. Turvey, Mari L. DeMarco, Kim‐Anh Lê Cao, Gail M. Gauvreau, J. Mark FitzGerald, Paul M. O’Byrne, Leah T. Stiemsma, Marie‐Claire Arrieta, Jasmine Cheng, Pedro A. Dimitriu, Lisa Thorson, Sophie Yurist, Diana L. Lefebvre, Piush J. Mandhane, Kelly M. McNagny, Tobias R. Kollmann, William W. Mohn, B. Brett Finlay, Maxwell Tran, Diana L. Lefebvre, Chinthanie Ramasundarahettige, Wei Dai, Piush J. Mandhane, Damian Tworek, Seamus N. O’Byrne, Paul M. O’Byrne, Judah A. Denburg, Laura Walsh, Mena Soliman, Lisa M. Steacy, Daniel E. Adams, Linda Sue Warner, Mary Ann Mauro, Robby Mamonluk, Chenxi Yang, Ed Conway,
... To food Allergies in a Registry of Twins Alizée Dery, Ann Clarke, Kari Nadeau, Laurie Harada, Kimberley ... Mill, Marie-Noel Primeau, Christine Lejtenyi, Elena Netchiporouk, Alizee Dery, Greg Shand, Moshe Ben-Shoshan A34 Validity ...
BioMed Central
... to the improved growing conditions was characteristic of Alizee (b i = 1.12),Upite 2 (b i = ... Laska ½Voskhod (b i = 2.16), Voskhod ½ Alizee (b i = 1.17),K-65 ½ Laska ( ...
Tópico(s): Agriculture and Biological Studies
2017 - Russian Academy of Agricultural Sciences | Sel skokhozyaistvennaya Biologiya
Florence Paynel, Claudine Morvan, Stéphane Marais, Laurent Lebrun,
... extracted from two spring fibre-varieties, Aurore and Alizee. The matrix was crosslinked with epichlorohydrin (T = 70 ° ... added as plasticizer. The composite was optimised with Alizee-mucilage extracted at 40 °C and with epichlorohydrin ...
Tópico(s): biodegradable polymer synthesis and properties
2012 - Elsevier BV | Polymer Degradation and Stability
Laure Resplandy, Allison Hogikyan, Jens Daniel Müller, Raymond G. Najjar, Hermann W. Bange, Daniele Bianchi, Thomas Weber, Wei‐Jun Cai, Scott C. Doney, Katja Fennel, Marion Gehlen, Judith Hauck, Fabrice Lacroix, Peter Landschützer, Corinne Le Quéré, Alizée Roobaert, Jörg Schwinger, Sarah Berthet, Laurent Bopp, Thi Tuyet Trang Chau, Minhan Dai, Nicolas Gruber, Tatiana Ilyina, Annette Kock, Manfredi Manizza, Zouhair Lachkar, Goulven G. Laruelle, Enhui Liao, Ivan D. Lima, Cara Nissen, Christian Rödenbeck, Roland Séférian, Katsuya Toyama, Hiroyuki Tsujino, Pierre Regnier,
Abstract The coastal ocean contributes to regulating atmospheric greenhouse gas concentrations by taking up carbon dioxide (CO 2 ) and releasing nitrous oxide (N 2 O) and methane (CH 4 ). In this second phase of the Regional Carbon Cycle Assessment and Processes (RECCAP2), we quantify global coastal ocean fluxes of CO 2 , N 2 O and CH 4 using an ensemble of global gap‐filled observation‐based products and ocean biogeochemical models. The global coastal ocean is a net sink of CO 2 in both observational products ...
Tópico(s): Oceanographic and Atmospheric Processes
2024 - Wiley | Global Biogeochemical Cycles
Matteo Morotti, Alizée J. Grimm, Helen Carrasco Hope, Marion Arnaud, Mathieu Desbuisson, Nicolas Rayroux, David Barras, María Masid, Baptiste Murgues, Bovannak Stewen Chap, Marco Ongaro, Ioanna A. Rota, Catherine Ronet, Aspram Minasyan, Johanna Chiffelle, Sebastian Lacher, Sara Bobisse, Clément Murgues, Eleonora Ghisoni, Khaoula Ouchen, Ribal Bou Mjahed, Fabrizio Benedetti, Naoill Abdellaoui, Riccardo Turrini, Philippe O. Gannon, Khalil Zaman, Patrice Mathevet, Loïc Lelièvre, Isaac Crespo, Marcus Conrad, Grégory Verdeil, Lana E. Kandalaft, Julien Dagher, Jesús Corría-Osorio, Marie‐Agnès Doucey, Ping‐Chih Ho, Alexandre Harari, Nicola Vannini, Jan P. Böttcher, Denarda Dangaj, George Coukos,
Abstract Expansion of antigen-experienced CD8 + T cells is critical for the success of tumour-infiltrating lymphocyte (TIL)-adoptive cell therapy (ACT) in patients with cancer 1 . Interleukin-2 (IL-2) acts as a key regulator of CD8 + cytotoxic T lymphocyte functions by promoting expansion and cytotoxic capability 2,3 . Therefore, it is essential to comprehend mechanistic barriers to IL-2 sensing in the tumour microenvironment to implement strategies to reinvigorate IL-2 responsiveness and T cell antitumour ...
Tópico(s): Immune cells in cancer
2024 - Nature Portfolio | Nature
Sebastian Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna‐Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas Rudolph, Nadine Spranger, Matteo Morotti, Alizée J. Grimm, Sebastian Jarosch, Arman Öner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H. Busch, Veit R. Buchholz, Percy A. Knolle, Dietmar Zehn, Denarda Dangaj, Sebastian Kobold, Jan P. Böttcher,
Abstract Cancer-specific TCF1 + stem-like CD8 + T cells can drive protective anticancer immunity through expansion and effector cell differentiation 1–4 ; however, this response is dysfunctional in tumours. Current cancer immunotherapies 2,5–9 can promote anticancer responses through TCF1 + stem-like CD8 + T cells in some but not all patients. This variation points towards currently ill-defined mechanisms that limit TCF1 + CD8 + T cell-mediated anticancer immunity. Here we demonstrate that tumour-derived prostaglandin ...
Tópico(s): T-cell and B-cell Immunology
2024 - Nature Portfolio | Nature
David Barras, Eleonora Ghisoni, Johanna Chiffelle, Angela Orcurto, Julien Dagher, Noémie Fahr, Fabrizio Benedetti, Isaac Crespo, Alizée J. Grimm, Matteo Morotti, Stefan Zimmermann, Rafael Durán, Martina Imbimbo, Maria Ochoa de Olza, Blanca Navarro, Krisztián Homicskó, Sara Bobisse, Danny Labes, Zoe Tsourti, Charitini Andriakopoulou, Fernanda G. Herrera, Rémy Pétremand, Reinhard Dummer, Grégoire Berthod, Anne I. Kraemer, Florian Huber, Jonathan Thévenet, Michal Bassani‐Sternberg, Niklaus Schaefer, John O. Prior, Maurice Matter, Veronica Aedo, Clarisse Dromain, Jesús Corría-Osorio, Stéphanie Tissot, Lana E. Kandalaft, Raphaël Gottardo, Mikaël J. Pittet, Christine Sempoux, Olivier Michielin, Urania Dafni, Lionel Trueb, Alexandre Harari, Denarda Dangaj, George Coukos,
Adoptive cell therapy (ACT) using ex vivo–expanded tumor-infiltrating lymphocytes (TILs) can eliminate or shrink metastatic melanoma, but its long-term efficacy remains limited to a fraction of patients. Using longitudinal samples from 13 patients with metastatic melanoma treated with TIL-ACT in a phase 1 clinical study, we interrogated cellular states within the tumor microenvironment (TME) and their interactions. We performed bulk and single-cell RNA sequencing, whole-exome sequencing, and spatial ...
Tópico(s): Single-cell and spatial transcriptomics
2024 - American Association for the Advancement of Science | Science Immunology
Shan Kothari, Rosalie Beauchamp‐Rioux, Florence Blanchard, Anna L. Crofts, Alizée Girard, Xavier Guilbeault‐Mayers, Paul W. Hacker, Juliana Pardo, Anna K. Schweiger, Sabrina Demers‐Thibeault, Anne Bruneau, Nicholas C. Coops, Margaret Kalácska, Mark Vellend, Étienne Laliberté,
Summary Plant ecologists use functional traits to describe how plants respond to and influence their environment. Reflectance spectroscopy can provide rapid, non‐destructive estimates of leaf traits, but it remains unclear whether general trait‐spectra models can yield accurate estimates across functional groups and ecosystems. We measured leaf spectra and 22 structural and chemical traits for nearly 2000 samples from 103 species. These samples span a large share of known trait variation and represent ...
Tópico(s): Spectroscopy and Chemometric Analyses
2023 - Wiley | New Phytologist
Alizée Lopez‐Persem, Sarah Moreno-Rodriguez, Marcela Ovando‐Tellez, Théophile Bieth, Stella Guiet, Jules Brochard, Emmanuelle Volle,
What drives us to search for creative ideas, and why does it feel good to find one? While previous studies demonstrated the positive influence of motivation on creative abilities, how reward and subjective values play a role in creativity remains unknown. This study proposes to characterize the role of individual preferences (how people value ideas) in creative ideation via behavioral experiments and computational modeling. Using the Free Generation of Associates Task coupled with rating tasks, we ...
Tópico(s): Neural and Behavioral Psychology Studies
2023 - American Psychological Association | American Psychologist
Nicolas Clairis, Alizée Lopez‐Persem,
Abstract The dorsomedial prefrontal cortex/dorsal anterior cingulate cortex (dmPFC/dACC) is a brain area subject to many theories and debates over its function(s). Even its precise anatomical borders are subject to much controversy. In the past decades, the dmPFC/dACC has been associated with more than 15 different cognitive processes, which sometimes appear quite unrelated (e.g. body perception, cognitive conflict). As a result, understanding what the dmPFC/dACC does has become a real challenge for ...
Tópico(s): Memory and Neural Mechanisms
2023 - Oxford University Press | Brain
Thibault Bourdin, Marie-Ève Benoit, Alizée Monnier, Émilie Bédard, Michèle Prévost, Dominique Charron, Nathalie Audy, Sophie Gravel, Mélanie Sicard, Caroline Quach, Eric Dézièl, Philippe Constant,
Compelling evidence suggests a contribution of the sink environment to the transmission of opportunistic pathogens from the hospital environment to patients in neonatal intensive care units (NICU). In this study, the distribution of the opportunistic pathogen Serratia marcescens in the sink environment and newborns in a NICU was investigated. More than 500 sink drain and faucet samples were collected over the course of five sampling campaigns undertaken over 3 years. Distribution and diversity of ...
Tópico(s): Antibiotic Resistance in Bacteria
2023 - American Society for Microbiology | Applied and Environmental Microbiology
Ian Hewson, Isabella T. Ritchie, James S. Evans, Ashley Altera, Donald C. Behringer, Erin Bowman, Marilyn E. Brandt, Kayla A. Budd, Ruleo Camacho, Tomas O. Cornwell, Peter D. Countway, Aldo Cróquer, Gabriel Delgado, Christopher M. DeRito, Elizabeth Duermit-Moreau, Ruth Francis‐Floyd, Samuel Gittens, Leslie M. Henderson, Alwin Hylkema, Christina A. Kellogg, Yasunari Kiryu, Kimani Kitson‐Walters, Patricia R. Kramer, Judith C. Lang, H. A. Lessios, Lauren Liddy, David Marancik, Stephen Nimrod, Joshua T. Patterson, Marit Pistor, Isabel C. Romero, Rita Sellares-Blasco, Moriah Sevier, William C. Sharp, Matthew Souza, Andreina Valdez-Trinidad, Marijn van der Laan, Brayan Vilanova-Cuevas, María F. Villalpando, Sarah D. Von Hoene, Matthew M. Warham, Tom Wijers, Stacey M. Williams, Thierry M. Work, Roy P. Yanong, Someira Zambrano, Alizee Zimmermann, Mya Breitbart,
Echinoderm mass mortality events shape marine ecosystems by altering the dynamics among major benthic groups. The sea urchin Diadema antillarum, virtually extirpated in the Caribbean in the early 1980s by an unknown cause, recently experienced another mass mortality beginning in January 2022. We investigated the cause of this mass mortality event through combined molecular biological and veterinary pathologic approaches comparing grossly normal and abnormal animals collected from 23 sites, representing ...
Tópico(s): Ocean Acidification Effects and Responses
2023 - American Association for the Advancement of Science | Science Advances
Avilien Dard, Alizée Weiss, Laetitia Bariat, Juline Auverlot, Valentine Fontaine, Nathalie Picault, Frédéric Pontvianne, Christophe Riondet, Jean‐Philippe Reichheld,
In the context of climate change, the global rise of temperature and intense heat waves affect plant development and productivity. Among the molecular perturbations that high temperature induces in living cells is the accumulation of reactive oxygen species (ROS), which perturbs the cellular redox state. In plants, the dynamics of the cellular and subcellular redox state have been poorly investigated under high temperature. Glutathione plays a major role in maintaining the cellular redox state. We ...
Tópico(s): Photosynthetic Processes and Mechanisms
2023 - Oxford University Press | Journal of Experimental Botany
Arnaud Jabet, Sarah Dellière, Sophie Seang, Aziza Chermak, Luminita Schneider, Thibault Chiarabini, A. Teboul, G. Hickman, Alizée Bozonnat, Cécile Brin, Marion Favier, Yanis Tamzali, François Chasset, Stéphane Barète, Samia Hamane, M. Benderdouche, Alicia Moreno‐Sabater, Éric Dannaoui, Christophe Hennequin, Arnaud Fekkar, Renaud Piarroux, Anne‐Cécile Normand, Gentiane Monsel,
Transmission of dermatophytes, especially Trichophyton mentagrophytes genotype VII, during sexual intercourse has been recently reported. We report 13 such cases in France. All patients were male; 12 were men who have sex with men. Our findings suggest sexual transmission of this pathogen within a specific population, men who have sex with men.
Tópico(s): Fungal Infections and Studies
2023 - Centers for Disease Control and Prevention | Emerging infectious diseases
Francesco Marchegiani, Leandro Siragusa, Alizée Zadoroznyj, Vito Laterza, Orsalia Mangana, Carlo Alberto Schena, Michele Ammendola, Riccardo Memeo, Paolo Pietro Bianchi, Giuseppe Spinoglio, Paschalis Gavriilidis, Nicola de’Angelis,
Background and Objectives: Robotic surgery has been widely adopted in general surgery worldwide but access to this technology is still limited to a few hospitals. With the recent introduction of new robotic platforms, several studies reported the feasibility of different surgical procedures. The aim of this systematic review is to highlight the current clinical practice with the new robotic platforms in general surgery. Materials and Methods: A grey literature search was performed on the Internet ...
Tópico(s): Colorectal Cancer Surgical Treatments
2023 - Multidisciplinary Digital Publishing Institute | Medicina
P. Tarantino, Giulia Viale, Michael F. Press, Xin Hu, Frédérique Penault‐Llorca, A. Bardia, Anna Batistatou, H.J. Burstein, L.A. Carey, Javier Cortés, C. Denkert, V. Diéras, William Jacot, A. Koutras, Alizée Lebeau, S. Loibl, Shanu Modi, M.F. Mosele, Elena Provenzano, Giancarlo Pruneri, Jorge S. Reis‐Filho, Federico Rojo, Roberto Salgado, P. Schmid, Stuart J. Schnitt, S.M. Tolaney, Dario Trapani, A. Vincent-Salomon, A.C. Wolff, George Pentheroudakis, Fabrice André, G. Curigliano,
Human epidermal growth factor receptor 2 (HER2)-low breast cancer has recently emerged as a targetable subset of breast tumors, based on the evidence from clinical trials of novel anti-HER2 antibody-drug conjugates. This evolution has raised several biological and clinical questions, warranting the establishment of consensus to optimally treat patients with HER2-low breast tumors. Between 2022 and 2023, the European Society for Medical Oncology (ESMO) held a virtual consensus-building process focused ...
Tópico(s): Breast Cancer Treatment Studies
2023 - Elsevier BV | Annals of Oncology
Alexandre Mansour, Erwan Flécher, Matthieu Schmidt, Bertrand Rozec, Isabelle Gouin‐Thibault, Maxime Esvan, Claire Fougerou, Bruno Lévy, Alizée Porto, James T. Ross, Marylou Para, Sabrina Manganiello, Guillaume Lebreton, André Vincentelli, Nicolas Nesseler, Marc Pierrot, Sidney Chocron, Guillaume Flicoteaux, Philippe Mauriat, Alexandre Ouattara, Hadrien Rozé, Olivier Huet, Marc‐Olivier Fischer, Claire Alessandri, Raphel Bellaïche, Ophélie Constant, Quentin de Roux, André Ly, Arnaud Meffert, Jean‐Claude Merle, Nicolas Mongardon, L Picard, Elena Skripkina, Thierry Folliguet, Antonio Fiore, Nicolas D’ostrevy, Marie-Catherine Morgan, Pierre-Grégoire Guinot, Maxime Nguyen, Lucie Gaide‐Chevronnay, Nicolas Terzi, Gwenhaël Colin, Olivier Fabre, Arash Astaneh, Justin Issard, Élie Fadel, Dominique Fabre, Antoine Girault, Julien Guihaire, Iolande Ion, Jean-Baptiste Ménager, Délphine Mitilian, Olaf Mercier, François Stéphan, Jacques Thès, Jérôme Jouan, Thibault Duburcq, Valentin Loobuyck, Mouhammed Moussa, A Mugnier, Natacha Rousse, Olivier Desebbe, Jean-Luc Fellahi, Roland Hénaine, Matteo Pozzi, Jean‐Christophe Richard, Zakaria Riad, Christophe Guervilly, Sami Hraiech, Laurent Papazian, Matthias Castanier, C. Chanavaz, Cyril Cadoz, Sébastien Gette, Guillaume Louis, Erick Portocarrero, Philippe Gaudard, Kais Brini, Nicolas Bischoff, Antoine Kimmoun, Mathieu Mattèi, Pierre Perez, Alexandre Bourdiol, Yannick Hourmant, Pierre-Joachim Mahé, Pierre Jaquet, Brice Lortat‐Jacob, Pierre Mordant, Patrick Nataf, Juliette Patrier, Sophie Provenchère, Morgan Roué, Romain Sonneville, Alexy Tran‐Dinh, Paul-Henri Wicky, Charles Al Zreibi, Bernard Cholley, Yannis Guyonvarch, Sophie Hamada, Anatole Harrois, Jordi Matiello, Thomas Kerforne, C. Lacroix, Nicolas Bréchot, Alain Combes, Juliette Chommeloux, Jean Michel Constantin, Cosimo D’Alessandro, Pierre Demondion, Alexandre Demoule, Martin Dres, Guillaume Fadel, Muriel Fartoukh, Guillaume Hékimian, Charles Juvin, Pascal Leprince, David Levy, Charles Edouard Luyt, Marc Pineton de Chambrun, Thibaut Schoell, Pierre Fillâtre, Nicolas Massart, Roxane Nicolas, Maud Jonas, Charles Vidal, Nicolas Allou, Salvatore Muccio, Dario Di Perna, Vito Giovanni Ruggieri, Bruno Mourvillier, Amédéo Anselmi, Karl Bounader, Yoann Launey, Thomas Lebouvier, Alessandro Parasido, Florian Reizine, Philippe Séguin, Emmanuel Besnier, Dorothée Carpentier, Thomas Clavier, Pierre‐Emmanuel Falcoz, Anne Olland, Marion Villard, Fanny Vardon‐Bounes, François Labaste, Vincent Minville, Antoine Guillon, Yannick Fédun,
To describe bleeding and thrombotic events and their risk factors in patients receiving extracorporeal membrane oxygenation (ECMO) for severe coronavirus disease 2019 (COVID-19) and to evaluate their impact on in-hospital mortality.The ECMOSARS registry included COVID-19 patients supported by ECMO in France. We analyzed all patients included up to March 31, 2022 without missing data regarding bleeding and thrombotic events. The association of bleeding and thrombotic events with in-hospital mortality ...
Tópico(s): Long-Term Effects of COVID-19
2022 - Springer Science+Business Media | Intensive Care Medicine
Nicolas Nesseler, Guillaume Fadel, Alexandre Mansour, Marylou Para, Pierre‐Emmanuel Falcoz, Nicolas Mongardon, Alizée Porto, Astrid Bertier, Bruno Lévy, Cyril Cadoz, Pierre-Grégoire Guinot, Olivier Fouquet, Jean-Luc Fellahi, Alexandre Ouattara, Julien Guihaire, Vito Giovanni Ruggieri, Philippe Gaudard, François Labaste, Thomas Clavier, Kais Brini, Nicolas Allou, C. Lacroix, Juliette Chommeloux, Guillaume Lebreton, Michael A. Matthay, Sophie Provenchère, Erwan Flécher, André Vincentelli,
Background Despite expanding use, knowledge on extracorporeal membrane oxygenation support during the COVID-19 pandemic remains limited. The objective was to report characteristics, management, and outcomes of patients receiving extracorporeal membrane oxygenation with a diagnosis of COVID-19 in France and to identify pre-extracorporeal membrane oxygenation factors associated with in-hospital mortality. A hypothesis of similar mortality rates and risk factors for COVID-19 and non–COVID-19 patients ...
Tópico(s): Cardiac Arrest and Resuscitation
2022 - Lippincott Williams & Wilkins | Anesthesiology
Alizée Lopez‐Persem, Théophile Bieth, Stella Guiet, Marcela Ovando‐Tellez, Emmanuelle Volle,
COVID-19 took us by surprise. We all had to face the lockdown and pandemic that put us in a new context, changing our way of life, work conditions, and habits. Coping with such an unprecedented situation may have stimulated creativity. However, the situation also restricted our liberties and triggered health or psychological difficulties. We carried out an online survey (n = 380) to examine whether and how the COVID-19 related first lockdown period was associated with creativity changes in French speaking ...
Tópico(s): Perfectionism, Procrastination, Anxiety Studies
2022 - Frontiers Media | Frontiers in Psychology
Lionel Gillot, Alizée Lebeau, Louis Baudin, Charles Pottier, Thomas Louis, Tania Durré, Rémi Longuespée, Gabriel Mazzucchelli, Christophe Nizet, Silvia Blacher, Frédéric Kridelka, Agnès Noël,
Although lymph node (LN) metastasis is an important prognostic parameter in cervical cancer, the tissue remodeling at a pre-metastatic state is poorly documented in LNs. We here identified periostin (POSTN) as a component of non-metastatic LNs by applying proteomic analyses and computerized image quantifications on LNs of patients with cervical cancer. We provide evidence for remarkable modifications of POSTN and lymphatic vessel distributions and densities in non-metastatic sentinel and metastatic ...
Tópico(s): Cancer Cells and Metastasis
2022 - Springer Nature | Cellular and Molecular Life Sciences
Alizée Ville, Grace Wong, Amanda Jiménez-Aceituno, Andrea S. Downing, Mawa Karambiri, Maria Brockhaus,
Gender equality in natural resource management is a matter of sustainability and democracy for Sweden's government, however the country's forest remains a highly gender-segregated sector. We examine how gender inequality is problematized within Swedish forest and rural policy documents using the What's the problem represented to be? (WPR) approach. We build on previous efforts to investigate gender inequality in the forest sector by expanding the critical analysis to rural development policy. We ...
Tópico(s): Bioeconomy and Sustainability Development
2022 - Elsevier BV | Environmental Science & Policy
Kgato P. Selwe, Jessica Thorn, Alizée O. S. Desrousseaux, Caroline E. H. Dessent, J. Brett Sallach,
Abstract The growing production and use of chemicals and the resultant increase in environmental exposure is of particular concern in developing countries where there is rapid industrialization and population growth but limited information on the occurrence of emerging contaminants. Advances in analytical techniques now allow for the monitoring of emerging contaminants at very low concentrations with the potential to cause harmful ecotoxicological effects. Therefore, we provide the first critical ...
Tópico(s): Water Treatment and Disinfection
2022 - Wiley | Environmental Toxicology and Chemistry
Isabelle K. Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S. Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Søren R. Paludan, Gaëtan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitriοs Vlachakis, Andrei Turtoï, Nadine Laguette,
Concerted alteration of immune and metabolic homeostasis underlies several inflammation-related pathologies, ranging from metabolic syndrome to infectious diseases. Here, we explored the coordination of nucleic acid-dependent inflammatory responses and metabolic homeostasis. We reveal that the STING (stimulator of interferon genes) protein regulates metabolic homeostasis through inhibition of the fatty acid desaturase 2 (FADS2) rate-limiting enzyme in polyunsaturated fatty acid (PUFA) desaturation. ...
Tópico(s): Inflammasome and immune disorders
2022 - Cell Press | Cell Metabolism
Pierre Deharo, Lionel Leroux, Alexis Théron, Jérôme Ferrara, Antoine Vaillier, Nicolas Jaussaud, Alizée Porto, Pierre Morera, Vlad Gariboldi, Bernard Iung, Thierry Lefévre, Philippe Commeau, Margaux Gouysse, Florence du Chayla, Nicolas Glatt, Guillaume Cayla, Herve Le Breton, Hakim Benamer, Sylvain Beurtheret, Jean Philippe Verhoye, Hélène Eltchaninoff, Martine Gilard, Jean‐Philippe Collet, Nicolas Dumonteil, Frédéric Collart, Thomas Modine, Thomas Cuisset,
Transcatheter aortic valve implantation (TAVI) is the preferred treatment for symptomatic severe aortic stenosis (AS) in a majority of patients across all surgical risks.Paravalvular leak (PVL) and patient-prosthesis mismatch (PPM) are two frequent complications of TAVI. Therefore, based on the large France-TAVI registry, we planned to report the incidence of both complications following TAVI, evaluate their respective risk factors, and study their respective impacts on long-term clinical outcomes, ...
Tópico(s): Coronary Interventions and Diagnostics
2022 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Nicolas Massart, Christophe Guervilly, Alexandre Mansour, Alizée Porto, Erwan Flécher, Maxime Esvan, Claire Fougerou, Pierre Fillâtre, Thibault Duburcq, Guillaume Lebreton, Marylou Para, François Stéphan, Sami Hraiech, James T. Ross, Matthieu Schmidt, André Vincentelli, Nicolas Nesseler,
OBJECTIVES: Prone positioning and venovenous extracorporeal membrane oxygenation (ECMO) are both useful interventions in acute respiratory distress syndrome (ARDS). Combining the two therapies is feasible and safe, but the effectiveness is not known. Our objective was to evaluate the potential survival benefit of prone positioning in venovenous ECMO patients cannulated for COVID-19–related ARDS. DESIGN: Retrospective analysis of a multicenter cohort. PATIENTS: Patients on venovenous ECMO who tested ...
Tópico(s): Cardiac Arrest and Resuscitation
2022 - Lippincott Williams & Wilkins | Critical Care Medicine
Mercedes Tkach, Jessie Thalmensi, Eleonora Timperi, Paul Gueguen, Nathalie Névo, Eleonora Grisard, Philémon Sirven, Federico Cocozza, Alizée Gouronnec, Lorena Martín‐Jaular, Mabel Jouve, Fabien Delisle, Nicolas Manel, Derek C. Rookhuizen, Coralie L. Guérin, Vassili Soumelis, Emanuela Romano, Elodie Ségura, Clotilde Théry,
Significance Our work uncovers mechanisms by which tumor cells impact tumor-associated macrophages in human triple-negative breast cancer. Via extracellular vesicles (EVs), these tumors promote macrophages with proinflammatory features, correlated with better clinical outcome. Our results suggest exploration of these EVs as tools, alone, or in combination with other therapies, to promote a favorable environment for the generation of anti-tumor immune responses.
Tópico(s): Reproductive System and Pregnancy
2022 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Alizée Lebeau, Diane Bruyère, Patrick Roncarati, Paul Peixoto, Éric Hervouet, Gaël Cobraiville, Bernard Taminiau, Murielle Masson, Carmen Gallego, Gabriel Mazzucchelli, Nicolas Smargiasso, Maximilien Fléron, Dominique Baiwir, Elodie Hendrick, Charlotte Pilard, Thomas Lerho, Célia Reynders, Marie Ancion, Roland Greimers, Jean‐Claude Twizere, Georges Daube, Géraldine Schlecht‐Louf, Françoise Bachelerie, Jean‐Damien Combes, Pierrette Melin, Marianne Fillet, Philippe Delvenne, Pascale Hubert, Michaël Herfs,
Despite the high prevalence of both cervico-vaginal human papillomavirus (HPV) infection and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV has been presumed to be a risk factor for HPV acquisition and related carcinogenesis for a long time, here, supported by both a large retrospective follow-up study (n = 6,085) and extensive in vivo data using the K14-HPV16 transgenic mouse model, we report a novel blueprint in which the opposite association also exists. Mechanistically, ...
Tópico(s): Reproductive System and Pregnancy
2022 - Nature Portfolio | Nature Communications
Amanda R. Fay, Luke Gregor, Peter Landschützer, Galen A. McKinley, Nicolas Gruber, Marion Gehlen, Yosuke Iida, Goulven G. Laruelle, Christian Rödenbeck, Alizée Roobaert, Jiye Zeng,
Abstract. Air–sea flux of carbon dioxide (CO2) is a critical component of the global carbon cycle and the climate system with the ocean removing about a quarter of the CO2 emitted into the atmosphere by human activities over the last decade. A common approach to estimate this net flux of CO2 across the air–sea interface is the use of surface ocean CO2 observations and the computation of the flux through a bulk parameterization approach. Yet, the details for how this is done in order to arrive at ...
Tópico(s): Climate variability and models
2021 - Copernicus Publications | Earth system science data
Clara Taffoni, Alizée Steer, Johanna Marines, Hanane Chamma, Isabelle K. Vila, Nadine Laguette,
The maintenance of genomic stability in multicellular organisms relies on the DNA damage response (DDR). The DDR encompasses several interconnected pathways that cooperate to ensure the repair of genomic lesions. Besides their repair functions, several DDR proteins have emerged as involved in the onset of inflammatory responses. In particular, several actors of the DDR have been reported to elicit innate immune activation upon detection of cytosolic pathological nucleic acids. Conversely, pattern ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2021 - Frontiers Media | Frontiers in Immunology