By Philip Webster, Political Reporter, By Jonathan Wills, From Paul Ellman, By Nicholas Timmins, From Richard Ford, By Our Political Reporter, From Andrew Thompson, From Ronald Faux, From a Correspondent, By Our Labour Correspondent, By Donald Macintyre Labour Corresdent, By Philip Webster, Rupert Morris, By Geraldine Norman, Sale Room Correspondent, By the Staff of "Nature", By Anthony Bevins, Political Correspondent, By David Hewson, By Stewart Tendler, Crime Reporter, By John Young, Agriculture Correspondent, By Paul Routledge, Labour Editor, By Clifford Longley, Religious Affairs Correspondent, By a Staff Reporter, By Baron Phillips, Property Correspondent, By Rupert Morris, By David Walker, By Hugh Clayton Environment Correspondent, From Christopher Walker, From Our Own Correspondent, From Nicholas Ashford, From Richard Wigg, From Alan McGregor, From Granla Forbes, From Roger Boyes, From Richard Owen, By Michael Knipe, From Patricia Clough, From Our Correspondent, From Hasan Akhtar, Richard Evans, From Ian Murray, From M G G Pillai, From Peter Nichols, From John Best, Peter Ackroyd, Nicholas Kenyon, Max Harrison, Stephen Pettitt, John Higgins, Patrick J. Smith, Stanley Sadie, John Percival, Judith Cruickshank, PHS, Andrew Nicol, Max Beloff, Gerald Kaufman, EDUARDO CRAWLEY, HUGH O'SHAUGHNESSY, MICHAEL FOOT, I. A. GEARING, MAXWELL FRY, N. OLWEN DAVIES, MICHAEL ADAMS, DAVID J. GOLDBERG, C. C. WRIGLEY, ALAN DASHWOOD, J W JOSEPHS, AUSTEN WILLIAMS, JOHN LANE, TONY SMYTHE, DAVID F. HENDRY, R. A. LEESON, CHRIS O'BRIEN, Sir Roger Bannister, City Editor Anthony Hilton, By Our Financial Staff, By Frances William Economics Correspondent, From John Earle, By Baron Phillips Property Correspondent, By Drew Johnston, By Peter Wilson-Smith, By Jonathan Davis Energy Correspondent, Clive Cookson, Maxwell Newton, By Our Correspondent, By Stuart Jones Football Correspondent, By Clive White, By Vince Wright, By Hugh Taylor, By Paul Newman, By Sydney Friskin, By Rex Bellamy, Tennis Correspondent, By Keith Macklin, From a Special Correspondent, From John Hennessy, From Tom Ramsey, By Lewine Mair, By Roy McKelvie, By David Hands, By Gordon Allan, By Richard Eaton, By Peter West Rugby Correspondent, By Gerald Davies, By Nicholas Keith, By Peter West, By Michael Seely, By Our Racing Staff, By Our Newmarket Correspondent, By Our Irish Correspondent, From Desmond Stoneham, by Baron Phillips, Edited by Peter Dear, By Henry Stanhope, Diplomatic Correspondent, DJM,
... victory, Nottingham, Classic with romantic qualities, Allison and Simonsen overshadow all, How the West was won by ...
1982 - Gale Group | TDA
D. William Cameron, LourdesJ D'Costa, GregoryM Maitha, Mary Cheang, Peter Piot, J. Neil Simonsen, Allan Ronald, MichaelN Gakinya, J O Ndinya-Achola, RobertC Brunham, F. A. Plummer,
Tópico(s): HIV, Drug Use, Sexual Risk
1989 - Elsevier BV | The Lancet
Christina B. Pedersen, Claus Bischoff, Ernst Christensen, Henrik Toft Simonsen, Allan M. Lund, Sarah P. Young, Dwight D. Koeberl, David S. Millington, Charles R. Roe, Diane S. Roe, Ronald J. A. Wanders, Jos P.N. Ruiter, Laura Davis Keppen, Quinn Stein, Inga Knudsen, Niels Gregersen, Brage Storstein Andresen,
The isobutyryl-CoA dehydrogenase (IBD) enzyme is involved in the degradation of valine. IBD deficiency was first reported in 1998 and subsequent genetic investigations identified acyl-CoA dehydrogenase (ACAD) 8, now IBD, as the gene responsible for IBD deficiency. Only three individuals homozygous or compound heterozygous for variations in the IBD gene have been reported. We present IBD deficiency in an additional four newborns with elevated C(4)-carnitine identified by tandem mass spectrometry (MS/ ...
Tópico(s): Mitochondrial Function and Pathology
2006 - Springer Nature | Pediatric Research
Gitte Gotholdt Jensen, Erland Björklund, Allan Simonsen, Bent Halling‐Sørensen,
An analytical method was developed for the determination of 2,6-dichlorobenzamide (BAM) and five degradation products thereof including 2-chlorobenzamide (OBAM), 2,6-dichlorobenzoic acid (DCBA), 2-chlorobenzoic acid (OBA), benzoic acid (BA) and benzamide (BAD) in water samples. Solid-phase extraction was combined with liquid chromatography coupled to tandem mass spectrometry using electrospray ionisation. Groundwater spiked at a concentration of 1.0 microg/L gave recoveries on day 1 between 91 and 102% ( ...
Tópico(s): Analytical Methods in Pharmaceuticals
2009 - Elsevier BV | Journal of Chromatography A
Sebastian R SÃ ̧rensen, Allan Simonsen, Jens Aamand,
The mineralization of the herbicide linuron at concentrations of microg and mg L(-1) was studied in liquid batch experiments with Variovorax sp. strain SRS16. The strain was highly efficient at mineralizing a range of linuron concentrations (0.002-10 mg L(-1)) with 20-60% of the added (14)C-ring-labeled linuron metabolized to (14)CO(2) within hours to days depending on the initial linuron concentration and incubation period. At mg L(-1) linuron concentrations the mineralization activity by SRS16 was ...
Tópico(s): Biocrusts and Microbial Ecology
2009 - Oxford University Press | FEMS Microbiology Letters
Allan Simonsen, Nora Badawi, Gitte Gotholdt Anskjær, Christian Nyrop Albers, Sebastian R. Sørensen, Jan Sørensen, Jens Aamand,
Tópico(s): Environmental Toxicology and Ecotoxicology
2011 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Sandra Reinnicke, Allan Simonsen, Sebastian R. Sørensen, Jens Aamand, Martin Elsner,
2,6-Dichlorobenzamide (BAM) is a metabolite of the herbicide 2,6-dichlorobenzonitrile (dichlobenil), and a prominent groundwater contaminant. Observable compound-specific isotope fractionation during BAM formation-through transformation of dichlobenil by Rhodococcus erythropolis DSM 9685-was small. In contrast, isotope fractionation during BAM degradation-with Aminobacter sp. MSH1 and ASI1, the only known bacterial strains capable of mineralizing BAM-was large, with pronounced carbon (ε(C) = -7.5‰ to - ...
Tópico(s): Microbial bioremediation and biosurfactants
2011 - American Chemical Society | Environmental Science & Technology
Allan Simonsen, Maria S. Holtze, Sebastian R. Sørensen, Søren J. Sørensen, Jens Aamand,
Mineralisation of the groundwater contaminant 2,6-dichlorobenzamide (BAM), a metabolite from the herbicide 2,6-dichlorobenzonitrile (dichlobenil), was studied in soil samples obtained from 39 locations previously exposed to dichlobenil. Rapid BAM mineralisation was detected in samples from six locations with 5.2–64.6% of the added BAM mineralised within 48–50 days. From one location rapid BAM mineralisation was observed in soil samples down to a depth of 2 m below the surface. One location with fast ...
Tópico(s): Analytical chemistry methods development
2006 - Elsevier BV | Environmental Pollution
Sebastian R. Sørensen, Maria S. Holtze, Allan Simonsen, Jens Aamand,
2,6-Dichlorobenzamide (BAM), a persistent metabolite from the herbicide 2,6-dichlorobenzonitrile (dichlobenil), is the pesticide residue most frequently detected in Danish groundwater. A BAM-mineralizing bacterial community was enriched from dichlobenil-treated soil sampled from the courtyard of a former plant nursery. A BAM-mineralizing bacterium (designated strain MSH1) was cultivated and identified by 16S rRNA gene sequencing and fatty acid analysis as being closely related to members of the genus ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2006 - American Society for Microbiology | Applied and Environmental Microbiology
Elizabeth Ngugi, J. Neil Simonsen, M Bosire, Allan Ronald, Francis A. Plummer, D. William Cameron, Peter G. Waiyaki, J.O. Ndinya‐Achola,
Condom use was assessed after a programme of education about the acquired immunodeficiency syndrome and a condom distribution programme in a well-characterised prostitute population in Nairobi. Women received their education at group meetings (barazas) and at individual counselling sessions during which they were given the results of serological tests for the human immunodeficiency virus (group 1) or at barazas only (group 2), or through very little of either (group 3). During the counselling sessions ...
Tópico(s): HIV/AIDS Research and Interventions
1988 - Elsevier BV | The Lancet
Ulla Knorr, Anja Hviid Simonsen, Peter Roos, Allan Weimann, Trine Henriksen, Ellen-Margrethe Christensen, Maj Vinberg, Rie Lambæk Mikkelsen, Thomas Kirkegaard, Rasmus Jensen, Morten Akhøj, Julie Lyng Forman, Henrik E. Poulsen, Steen Gregers Hasselbalch, Lars Vedel Kessing,
Abstract Bipolar disorder (BD) is a mental disorder characterized by recurrent relapses of affective episodes, cognitive impairment, illness progression, and reduced life expectancy. Increased systemic oxidatively generated nucleoside damage have been found in some neurodegenerative disorders and in BD. As the first, this naturalistic prospective, longitudinal follow-up case-control study investigated cerebrospinal fluid (CSF) oxidative stress markers 8-oxo-7,8-dihydroguanosine (8-oxoGuo) and 8-oxo- ...
Tópico(s): Acute Lymphoblastic Leukemia research
2019 - Springer Nature | Translational Psychiatry
Pernille Falberg Rønn, Tine Dalby, Jacob Simonsen, Charlotte Sværke Jørgensen, Allan Linneberg, Karen A. Krogfelt,
An increase in pertussis has been observed in several countries over the last decades, especially in adult populations. The seroprevalence of pertussis was determined in a cross-sectional study of the adult population in the Copenhagen area, Denmark, conducted between 2006 and 2008. Specific IgG antibodies against pertussis toxin (PT) were measured in 3440 persons resulting in an age-standardized seroprevalence of 3.0% (95% confidence interval 1.9-4.7) using an IgG anti-PT cut-off of 75 IU/ml. By ...
Tópico(s): Pneumonia and Respiratory Infections
2013 - Cambridge University Press | Epidemiology and Infection
Jane Angel Simonsen, Hans Mickley, Allan Johansen, Søren Hess, Anders Thomassen, Oke Gerke, Lisette Okkels Jensen, Jesper Hallas, Werner Vach, Poul Flemming Høilund‐Carlsen,
Objectives In stable coronary artery disease (CAD), coronary revascularisation may reduce mortality of patients with a certain amount of left ventricular myocardial ischaemia. However, revascularisation does not always follow the guidance suggested by ischaemia testing. We compared outcomes in patients without ischaemia who had either revascularisation or medical treatment. Design and population Based on registries, 1327 consecutive patients with normal myocardial perfusion scintigraphy (MPS) and ...
Tópico(s): Advanced MRI Techniques and Applications
2017 - BMJ | BMJ Open
Allan Linneberg, Jacob Simonsen, Janne Petersen, Lone Graff Stensballe, Christine Stabell Benn,
Atopic dermatitis (AD) often develops in infancy as the first manifestation of the atopic phenotype. Wheezing is also common in infancy, but it is less clear whether infant wheezing should be considered as an atopic phenotype. If infant wheeze and AD share a common aetiology, this would indicate that infant wheezing is an atopic phenotype. To investigate whether potential risk factors for infant wheeze and AD have similar effects on these 2 phenotypes, indicating a common etiology. A total of 34. ...
Tópico(s): Infant Health and Development
2005 - Elsevier BV | Journal of Allergy and Clinical Immunology
Ulrick Espelund, Henning Grønbæk, Gerda Elisabeth Villadsen, Kira Simonsen, P. Vestergaard, Jens Otto Lunde Jørgensen, Allan Flyvbjerg, Hendrik Vilstrup, Jan Frystyk,
Previous studies have demonstrated an elevated IGF-II mRNA expression and protein levels in tumors and blood from patients with hepatocellular carcinoma (HCC), hereby suggesting a role of IGF-II as a pathogenic marker of HCC. We hypothesized that in HCC, an increased IGF-II secretion would translate into an elevated circulating IGF bioactivity, which would normalize following treatment. Patients with HCC (n = 39) were studied before and after radio-frequency ablation and/or transarterial chemo-embolization. ...
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2015 - Elsevier BV | Growth Hormone & IGF Research
Jane Angel Simonsen, Allan Johansen, Oke Gerke, Hans Mickley, Anders Thomassen, Søren Hess, Charlotte Krogh Rask, Mohammad Tamadoni, Lisette Okkels Jensen, Jesper Hallas, Werner Vach, Poul Flemming Høilund‐Carlsen,
This study evaluated the combined influence of perfusion defects and left ventricular function on outcomes with revascularization vs medical therapy in stable CAD patients based on myocardial perfusion scintigraphy findings.
Tópico(s): Acute Myocardial Infarction Research
2016 - European Association of Percutaneous Cardiovascular Interventions | EuroIntervention
Allan Buhl Nielsen, Ole Simonsen,
Internal fixation with AO compression plates was carried out in 8 per cent of all children with displaced diaphyseal fractures of the forearm. Primary treatment for 23 of these 43 fractures consisted of primary fixation. All fractures healed in anatomical alignment. Deep infection was observed in 1 child. All fractures united but 1 refractured . Of 29 children, 27 were reexamined after a mean observation time of 5 years; 22 had obtained normal function of the arm, and nobody had restriction of rotation ...
Tópico(s): Elbow and Forearm Trauma Treatment
1984 - Elsevier BV | Injury
K. Sukumar Varma, Naoki Sasaki, Robert A. Clark, Allan E. Underhill, Ole Simonsen, J. BECHER, S. Bøwadt,
Abstract [1,4]Dithiino[2,3‐ b ]‐1,4‐Dithiin ( 3 ) has been synthesised in high yield by a one‐step procedure starting with sodium 1,3‐dithiole‐2‐thione‐4,5‐dithiolate ( 2 ). The X‐ray crystal structure shows non‐planarity of the fused ring system as well as short intermolecular S ⃜S contacts.
Tópico(s): Organic Chemistry Cycloaddition Reactions
1988 - Wiley | Journal of Heterocyclic Chemistry
D. William Cameron, Elizabeth Ngugi, Allan Ronald, J. Neil Simonsen, M R Braddick, M Bosire, J.M. Kimata, Janeth Kamala, J O Ndinya-Achola, P G Waiyaki, Francis A. Plummer,
CAMERON, D. WILLIAM MD; NGUGI, ELIZABETH N. PHD; RONALD, A. R. MD; SIMONSEN, J. N. MD; BRADDICK, M. MBChB; BOSIRE, M. RN; KIMATA, J.; KAMALA, J.; NDINYA-ACHOLA, J. O. MBChB; WAIYAKI, P. G. PHD; PLUMMER, F. A. MD Author Information
Tópico(s): Female Genital Mutilation/Cutting Issues
1991 - Lippincott Williams & Wilkins | Sexually Transmitted Diseases
Tove Hels, Allan Lyckegaard, Kirsten Wiese Simonsen, Anni Steentoft, Inger Marie Bernhoft,
Driving with alcohol and other psychoactive substances imposes an increased risk of severe injury accidents. In a population-based case–control design, the relative risks of severe driver injury (MAIS ≥ 2) by driving with ten substance groups were approximated by odds ratios (alcohol, amphetamines, benzoylecgonine, cocaine, cannabis, illicit opiates, benzodiazepines and Z-drugs, i.e. zolpidem and zopiclone, medicinal opioids, alcohol–drug combinations and drug–drug combinations). Data from six countries ...
Tópico(s): Substance Abuse Treatment and Outcomes
2013 - Elsevier BV | Accident Analysis & Prevention
Kasper Kristensen, Trine B. Engel, Allan Stensballe, Jens B. Simonsen, Thomas L. Andresen,
The protein corona is widely recognized as a key concept in contemporary nanomedicine. In recent years, the interest in the protein corona has reached new heights as a number of reports have suggested that a comprehensive protein corona can form around nanomaterials that previously were thought to be resistant to protein binding. For example, PEGylated stealth liposomes were long thought to be protein repellent, but a number of recent studies have found that a significant protein corona forms around ...
Tópico(s): Characterization and Applications of Magnetic Nanoparticles
2019 - Elsevier BV | Journal of Controlled Release

Amand F. Schmidt, Daniel I. Swerdlow, Michael V. Holmes, Riyaz Patel, Zammy Fairhurst-Hunter, Donald M. Lyall, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hyppönen, Christine Power, Max Moldovan, Erik Van Iperen, G. Kees Hovingh, Ilja Demuth, Kristina Norman, Elisabeth Steinhagen‐Thiessen, Juri Demuth, Lars Bertram, Tian Liu, Stefan Coassin, Johann Willeit, Stefan Kiechl, Karin Willeit, Dan Mason, John Wright, Richard Morris, Goya Wanamethee, Peter H. Whincup, Yoav Ben‐Shlomo, Stela McLachlan, Jackie F. Price, Mika Kivimäki, Catherine Welch, Adelaida Sánchez-Gálvez, Pedro Marques‐Vidal, Andrew Nicolaides, Andrie G. Panayiotou, N. Charlotte Onland‐Moret, Yvonne T. van der Schouw, Giuseppe Matullo, Giovanni Fiorito, Simonetta Guarrera, Carlotta Sacerdote, Nicholas J. Wareham, Claudia Langenberg, Robert A. Scott, Jian’an Luan, Martin Bobák, Sofia Malyutina, Andrzej Pająk, Růžena Kubínová, Abdonas Tamošiūnas, Hynek Pikhart, Lise Lotte N. Husemoen, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Kenneth Starup Simonsen, Jackie A. Cooper, Steve E. Humphries, Murray H. Brilliant, Terrie Kitchner, Hákon Hákonarson, David Carrell, Catherine A. McCarty, H. Lester Kirchner, Eric B. Larson, David R. Crosslin, Mariza de Andrade, Dan M. Roden, Joshua C. Denny, Cara L. Carty, Stephen Hancock, John Attia, Elizabeth G. Holliday, Martin O’Donnell, Salim Yusuf, Michael Chong, Guillaume Paré, Pim van der Harst, M. Abdullah Said, Ruben N. Eppinga, Niek Verweij, Harold Snieder, Tim Christen, Dennis O. Mook‐Kanamori, Stefan Gustafsson, Lars Lind, Erik Ingelsson, Raha Pazoki, Oscar H. Franco, Albert Hofman, André G. Uitterlinden, Abbas Dehghan, Alexander Teumer, Sebastian E. Baumeister, Marcus Dörr, Markus M. Lerch, Uwe Völker, Henry Völzke, Joey Ward, Jill P. Pell, Daniel J. Smıth, Tom Meade, Anke H. Maitland‐van der Zee, E.V. Baranova, Robin Young, Ian Ford, Archie Campbell, Sandosh Padmanabhan, Michiel L. Bots, Diederick E. Grobbee, Philippe Froguel, Dorothée Thuillier, Beverley Balkau, Amélie Bonnefond, Bertrand Cariou, Melissa Smart, Yanchun Bao, Meena Kumari, Anubha Mahajan, Paul M. Ridker, Daniel I. Chasman, Alex P. Reiner, Leslie A. Lange, Marylyn D. Ritchie, Folkert W. Asselbergs, Juan-Pablo Casas, Brendan J. Keating, David Preiss, Aroon D. Hingorani, Naveed Sattar,
Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but also with modest hyperglycaemia, increased bodyweight, and modestly increased risk of type 2 diabetes, which in no way offsets their substantial benefits. We sought to investigate the associations of LDL cholesterol-lowering PCSK9 variants with type 2 diabetes and related biomarkers to gauge the likely effects ...
Tópico(s): Genetic Associations and Epidemiology
2016 - Elsevier BV | The Lancet Diabetes & Endocrinology
Lars‐Georg Hersoug, Christine Stabell Benn, Jacob Simonsen, Mads Kamper‐Jørgensen, Allan Linneberg,
It has been proposed that exposure to infections and microbes protects against atopic diseases, but epidemiological data has so far been conflicting. We hypothesized that maternal exposure to infections and microbes before or during pregnancy would be of particular importance. To test this hypothesis, we studied the incidence of wheezing and atopic dermatitis (AD) in infants of mothers employed in child-care institutions - and thus presumably being highly exposed to infections and microbes - compared ...
Tópico(s): Dermatology and Skin Diseases
2008 - Wiley | Pediatric Allergy and Immunology
Jacob Simonsen, Kåre Mølbak, Gerhard Falkenhorst, Karen A. Krogfelt, Allan Linneberg, Peter Teunis,
Abstract Owing to underascertainment it is difficult if not impossible to determine the incidence of a given disease based on cases notified to routine public health surveillance. This is especially true for diseases that are often present in mild forms as for example diarrhoea caused by foodborne bacterial infections. This study presents a Bayesian approach for obtaining incidence estimates by use of measurements of serum antibodies against Salmonella from a cross‐sectional study. By comparing ...
Tópico(s): SARS-CoV-2 detection and testing
2009 - Wiley | Statistics in Medicine
Jacob Simonsen, M. A. STRID, Kåre Mølbak, Karen A. Krogfelt, Allan Linneberg, Peter Teunis,
SUMMARY Although most foodborne infections are undiagnosed, the incidence of these infections is usually calculated from reported cases. We present a novel population-based method to estimate the incidence of non-typhoid Salmonella infections. From 154 patients with confirmed Salmonella serotype Enteritidis infection, we determined the kinetics of the antibody response. The estimated mean responses for the three classes of serum antibodies were combined such that the time from infection could be ...
Tópico(s): Viral gastroenteritis research and epidemiology
2007 - Cambridge University Press | Epidemiology and Infection
Morten Simonsen Dueholm, Mads T. Søndergaard, Martin Nilsson, Gunna Christiansen, Allan Stensballe, Michael T. Overgaard, Michael Givskov, Tim Tolker‐Nielsen, Daniel E. Otzen, Per Halkjær Nielsen,
The fap operon, encoding functional amyloids in Pseudomonas (Fap), is present in most pseudomonads, but so far the expression and importance for biofilm formation has only been investigated for P. fluorescens strain UK4. In this study, we demonstrate the capacity of P. aeruginosa PAO1, P. fluorescens Pf-5, and P. putida F1 to express Fap fibrils, and investigated the effect of Fap expression on aggregation and biofilm formation. The fap operon in all three Pseudomonas species conferred the ability ...
Tópico(s): Oral microbiology and periodontitis research
2013 - Wiley | MicrobiologyOpen
Anders Jørgensen, Jonatan M. Staalsoe, Anja Hviid Simonsen, Steen Gregers Hasselbalch, Peter Høgh, Allan Weimann, Henrik E. Poulsen, N.V. Olsen,
Free radical toxicity is considered as a key mechanism in the neuronal damage occurring after aneurysmal subarachnoid haemorrhage (SAH). We measured markers of DNA and RNA damage from oxidation (8-oxodG and 8-oxoGuo, respectively) in cerebrospinal fluid from 45 patients with SAH on day 1-14 after ictus and 45 age-matched healthy control subjects. At baseline, both markers were significantly increased in patients compared to controls (p values < .001), and exhibited a progressive further increase (to >20- ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2017 - Taylor & Francis | Free Radical Research
Allan Weimann, Anja Hviid Simonsen, Henrik E. Poulsen,
Increased levels of nucleosides modified by oxidation in human cerebrospinal fluid (CSF) have several times been reported in Alzheimer patients and patients suffering from Parkinson's disease. The focus has especially been on nucleosides containing the 8-hydroxylation of guanine. Only few reports on quantification of the ribonucleoside 8-oxo-7,8-dihydro-guanosine (8oxoGuo) in CSF have been published, whereas more have been published on the quantification of the deoxy-ribonucleoside 8-oxo-7,8-dihydro- ...
Tópico(s): DNA Repair Mechanisms
2017 - Elsevier BV | Journal of Chromatography B
Allan Simonsen, N.G. Deen, Kim Sørensen, Thomas Condra, Lasse Rosendahl,
Eulerian-Lagrangian simulations often require a two-way coupling, where the discrete phase affects the continuous phase and vice versa. The continuous phase in a CFD-simulation is typically represented on a computational mesh, which consists of a number of discrete cells. As the discrete phase is not directly associated with this mesh, a mapping from the discrete phase to the continuous phase is required in order to couple the two phases. This will distribute the exchange rates from the discrete ...
Tópico(s): Lattice Boltzmann Simulation Studies
2019 - Elsevier BV | Computers & Fluids
Florian‐Alexander Herbst, Mads T. Søndergaard, Henrik Kjeldal, Allan Stensballe, Per Halkjær Nielsen, Morten Simonsen Dueholm,
The newly identified functional amyloids in Pseudomonas (Fap) are associated with increased aggregation and biofilm formation in the opportunistic pathogen P. aeruginosa; however, whether this phenomenon can be simply ascribed to the mechanical properties of the amyloid fibrils remains undetermined. To gain a deeper understanding of the Fap-mediated biofilm formation, the physiological consequences of Fap expression were investigated using label-free protein quantification. The functional amyloids ...
Tópico(s): Oral microbiology and periodontitis research
2014 - American Chemical Society | Journal of Proteome Research