Vanessa Alpalhão, Miguel Alpalhão,
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Tópico(s): COVID-19 and healthcare impacts
2020 - Oxford University Press | Physical Therapy
Vera Pires, Luı́s Guerra Rosa, Pedro M. Amaral, Amélia Dionísio, Joaquim Simão,
... Three granites—Amarelo de Vila Real, Cinzento de Alpalhão, and Cinzento de Pedras Salgadas—and two limestones— ... to recognize that only one granite, Cinzento de Alpalhão, presented lower failure risk in a cladding application. ...
Tópico(s): Conservation Techniques and Studies
2022 - American Society of Civil Engineers | Journal of Materials in Civil Engineering
Miguel Alpalhão, Nuno Gaibino, Paulo Filipe,
... dermatitis in COVID-19: a case report Miguel Alpalhão MD, Corresponding Author Miguel Alpalhão MD [email protected] orcid.org/0000-0001-7672- ... PortugalSearch for more papers by this author Miguel Alpalhão MD, Corresponding Author Miguel Alpalhão MD [email protected] orcid.org/0000-0001-7672- ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2020 - Wiley | International Journal of Dermatology
Miguel Alpalhão, João Borges‐Costa, Paulo Filipe,
Psoriasis is a prevalent systemic immune-mediated disease with cutaneous manifestations. In HIV-infected patients, psoriasis may have a higher incidence, present atypical and more exuberant clinical features, and is frequently recalcitrant to treatment. Despite this aggravated severity, treatment options for psoriasis in HIV-infected individuals remain limited due to the risk of fatal immunosuppression associated with both classical immunosuppressants and new biological drugs. Notwithstanding, drug ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2019 - SAGE Publishing | International Journal of STD & AIDS
Ana B. Oliveira, Miguel Alpalhão, Paulo Filipe, João Maia‐Silva,
Alopecia areata (AA) is a non-scarring alopecia, which often carries a major impact on patients' quality of life. Currently there is no single approved treatment that effectively induces permanent remission. Recently, the JAK-STAT signaling pathway has emerged as a possible therapeutic target leading to increased interest in the use of Janus kinase (JAK) inhibitors (JAKis) in the treatment of this pathology. This review of the literature summarizes information on patients with AA who underwent treatment ...
Tópico(s): Skin and Cellular Biology Research
2019 - Wiley | Dermatologic Therapy
Miguel Alpalhão, João Ferreira, Paulo Filipe,
The current SARS-CoV-2 has put significant strain on healthcare services worldwide due to acute COVID-19. However, the potential long-term effects of this infection haven't been extensively discussed. We hypothesize that SARS-CoV-2 may be able to cause persistent infection in some individuals, and should this be the case, that in a few years we may see a rise in cancer incidence due to carcinogenic effects of this coronavirus. Non-retroviral RNA viruses such as Coronaviridae have been shown to cause ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Elsevier BV | Medical Hypotheses
Miguel Alpalhão, Paulo Filipe,
Tópico(s): LGBTQ Health, Identity, and Policy
2020 - Springer Science+Business Media | AIDS and Behavior
Vítor Borges, Mariana Duque, João Vieira Martins, Paula Vasconcelos, Rita Ferreira, Daniel Sobral, Ana Pelerito, Isabel Lopes de Carvalho, Maria Sofia Núncio, Maria José Borrego, Cornelius Roemer, Richard A. Neher, Megan O’Driscoll, Raquel Rocha, Sílvia Lopo, Raquel Neves, Paula Palminha, Luís Coelho, Alexandra Nunes, Joana Isidro, Miguel Pinto, João Dourado Santos, Verónica Mixão, Daniela Santos, Sílvia Duarte, Luı́s Vieira, Fátima Martins, Jorge Machado, Vítor Cabral Veríssimo, Berta Grau-Pujol, André Peralta‐Santos, José Neves, Margarida Caldeira, Mafalda Pestana, Cândida Fernandes, João Caria, Raquel Pinto, Diana Póvoas, Fernando Maltêz, Ana Isabel Sá, Mafalda Brito Salvador, Eugénio Teófilo, Miguel Rocha, Virgínia Moneti, Luís Duque, Francisco Ferreira e Silva, Teresa Baptista, Joana Vasconcelos, Sara Casanova, Kamal Mansinho, João Vaz Alves, João M. P. Alves, António Silva, Miguel Alpalhão, Cláudia Brazão, Diogo de Sousa, Paulo Filipe, Patrícia Pacheco, Francesca Peruzzu, Rita Patrocínio de Jesus, Luís Ferreira, Josefina Mendez, Sofia Jordão, Frederico Duarte, Maria João Gonçalves, Eduarda Pena, Cláudio Silva, André Rodrigues Guimarães, Margarida Tavares, Graça Freitas, Rita Cordeiro, João Paulo Gomes,
Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the highest impact on case numbers and fitted them into a global context, finding evidence that ...
Tópico(s): Herpesvirus Infections and Treatments
2023 - Nature Portfolio | Nature Medicine
Rita Bouceiro-Mendes, Miguel Alpalhão, Paulo Filipe,
Abstract Vitiligo is a chronic pigmentary skin disorder that results in white, hypopigmented macules and patches. It causes a considerable psychological and emotional burden on the affected individuals and their families. Several therapeutic options have been employed in vitiligo including topical and oral drugs, surgical techniques, and phototherapy which is considered the cornerstone treatment. Different wavelengths and modalities are available, but narrowband UVB (NB‐UVB) is considered the safest ...
Tópico(s): Skin Protection and Aging
2021 - Wiley | Photodermatology Photoimmunology & Photomedicine
Miguel Alpalhão, Paulo Filipe,
None.
Tópico(s): Dermatological and COVID-19 studies
2021 - Wiley | Journal of the European Academy of Dermatology and Venereology
Miguel Alpalhão, Joana Vieitez Frade, Diogo de Sousa, João Patrocínio, Pedro Garrido, Catarina Correia, Cláudia Brazão, Dora Mancha, Maria José Borrego, Paulo Filipe,
An outbreak of monkeypox has emerged, with more than 2000 cases confirmed across the globe. While this condition, caused by the Monkeypox virus, a member of the Orthopoxvirus genus, is usually considered a zoonosis,1 we may be facing a sexually transmissible infection (STI), with yet uncertain consequences. In Portugal, we are seeing many suspected cases a day, most of which have been confirmed. At our department, we have had more than 20 confirmed cases, most of which in individuals with concomitant ...
Tópico(s): Bacillus and Francisella bacterial research
2022 - Wiley | Journal of the European Academy of Dermatology and Venereology
Vanessa Alpalhão, Nuno Cordeiro, Pedro Pezarat‐Correia,
A scoping review was performed to examine the extent and nature of research activity on kinesiophobia and fear avoidance in older adults and summarize research findings. Four databases were searched from January 2006 to May 2021. Eleven papers were selected for inclusion, with a predominance of cross-sectional design (54.5%; n = 6). Most of the studies were associated with chronic pain (n = 9; 81.8%). Higher levels of kinesiophobia were found among frailer and older people, predominantly living in care ...
Tópico(s): Behavioral Health and Interventions
2022 - Human Kinetics | Journal of Aging and Physical Activity
Miguel Alpalhão, Diogo de Sousa, Joana Vieitez Frade, João Patrocínio, Pedro Garrido, Catarina Correia, Cláudia Brazão, Dora Mancha, Maria Sofia Núncio, Isabel Lopes de Carvalho, Ana Pelerito, Maria José Borrego, Paulo Filipe,
To the Editor: An outbreak of monkeypox has emerged, and more than 13,000 cases have already been confirmed worldwide. In our department, we have 42 confirmed cases so far. All of them are cisgender males presenting with lesions in the genital, perianal, or perioral areas (Fig 1). Interestingly, we observe a disproportionate number of individuals living with the human immunodeficiency virus (HIV). Below, we present a retrospective analysis of our confirmed cases with their clinical and epidemiological ...
Tópico(s): Plant Virus Research Studies
2022 - Elsevier BV | Journal of the American Academy of Dermatology
José Vítor M.B. Vieira Lisboa, Jorge M. F. Carvalho, Roosevelt de Lima Sardinha,
“Alpalhão granite”, also called SPI, is used as a high quality ornamental stone for interior and exterior ...
Tópico(s): Recycling and utilization of industrial and municipal waste in materials production
2013 - Trans Tech Publications | Key engineering materials
Miguel Alpalhão, Luís Uva, Gilda Soromenho, Paulo Filipe,
Skin conditions frequently lead to emergency department (ED) visits. While most are benign in course, some will present as true dermatological urgencies/emergencies, requiring admission. To present data on skin diseases most frequently found in the ED, and those most frequently requiring admission at the largest Portuguese tertiary teaching hospital, and to explore an association between epidemiological variables and frequency of diagnoses within this context. A retrospective study was conducted ...
Tópico(s): Eosinophilic Disorders and Syndromes
2016 - John Libbey Eurotext | European Journal of Dermatology
Abstract Estimates of appropriate equity risk premiums are abundant in finance textbooks. Unfortunately, these estimates are ill suited to small and data scarce markets such as the Portuguese. The literature is reviewed to select techniques to overcome this difficulty, and estimates of equity risk premiums suited to the Portuguese market produced. Historical equity premiums are computed and the study finds what is believed to be a better understanding of the subject with the help of the Godfrey– ...
Tópico(s): Financial Risk and Volatility Modeling
2005 - Chapman and Hall London | Applied Financial Economics
Vera Pires, André Pacheco, V. Infante, Pedro M. Amaral, Luı́s Guerra Rosa,
... materials and ornamental stones, Portuguese granites Cinzento de Alpalhão (SPI) and Amarelo de Vila Real (AVR) are ...
Tópico(s): Innovations in Concrete and Construction Materials
2013 - Trans Tech Publications | Key engineering materials
Miguel Alpalhão, Paulo Filipe,
The current SARS-CoV-2 pandemic has mandated significant isolation measures. Streets in affected countries are mostly empty, and many individuals spend several consecutive days at home to reduce the risk of infection. While determinant for pandemic control, home reclusion may have a significant toll on the health of individuals. One relevant area where we are yet to see proper discussion and strategies pertains to vitamin D deficiency. Vitamin D is a fat-soluble hormone that plays a significant ...
Tópico(s): Bone health and osteoporosis research
2020 - Wiley | Photodermatology Photoimmunology & Photomedicine
Miguel Alpalhão, João Maia‐Silva, Paulo Filipe,
We are entering a new stage of the severe acute respiratory syndrome coronavirus 2 pandemic with the initiation of large-scale vaccination programs globally. In these circumstances, even rare adverse effects of vaccines may be encountered more often, if millions of people are to be vaccinated in a short period. Vaccination has the potential for causing cutaneous adverse effects. Thus, it is paramount that dermatologists worldwide are acquainted with the possible skin reaction patterns to the coming ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Lippincott Williams & Wilkins | Dermatitis
Tiago Torres, Maria João Paiva Lopes, Margarida Gonçalo, Cristina Claro, Maria Júlia Ribeiro de Oliveira, Joana Gomes, Ana Paula Vieira, Patrícia Amoedo, Miguel Alpalhão, Miguel Nogueira, Felicidade Santiago, Martinha Henrique, C. Amaro, Tiago Esteves, Juliana de Jesus Monteiro Alves, Diogo Cerejeira, Pedro Mendes‐Bastos, Mafalda Pestana, Lina Ramos, J. Rocha, Rita Carvalho, Laetitia Teixeira, Manuela Selores, Alberto Mota, Paulo Filipe,
Atopic dermatitis (AD) is a difficult-to-treat inflammatory skin disease with a high impact on patients' quality of life. Dupilumab, an IL-4 and IL-13 inhibitor, was the first monoclonal antibody approved for the treatment of moderate-to-severe AD and is currently approved in patients aged 6 or older.This is a nationwide, multicenter, retrospective, 48-week study designed by the Portuguese Group of AD to assess real-world efficacy and safety of dupilumab for the treatment of AD.A total of 169 patients ...
Tópico(s): Urticaria and Related Conditions
2022 - Informa | Journal of Dermatological Treatment
Bruno Jardim, Miguel de Castro Neto, Nuno Alpalhão, Paulo Calçada,
The SARS-CoV-2 outbreak motivated the development of a myriad of weekly and daily indicators that track economic activity to estimate and predict the consequences of the pandemic. With some exceptions, these indicators are calculated at the country level and are mainly focused on tracking economic factors, disregarding local urban phenomena. To address this, we present the Urban Dynamic Indicator (UDI), a novel composite indicator designed to measure a city's daily urban dynamic. The UDI is applied ...
Tópico(s): Impact of Light on Environment and Health
2022 - Elsevier BV | Sustainable Cities and Society
Vanessa Alpalhão, Nuno Cordeiro, Pedro Pezarat‐Correia,
In light of the fear avoidance model, kinesiophobia and fear avoidance (FA) can lead to physical inactivity and disability. Previous studies regarding kinesiophobia and FA in older adults have reported conflicting results. The purpose of this review was to identify the reported constructs and assessment instruments used in published studies on kinesiophobia and FA in older adults and to verify the alignment between the instruments used and the constructs under study.Following the Preferred Reporting ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2022 - Lippincott Williams & Wilkins | Journal of Geriatric Physical Therapy
Gail Pool, J. António Alpalhão, Victor M. P. Da Rosa,
Tópico(s): Multiculturalism, Politics, Migration, Gender
1981 - University of Toronto Press | Anthropologica
A. Alpalhão, Cláudia Neto, C.M. Oliveira, I. P. Lourenço, João Antônio Pêgas Henriques, J. Clemente,
Tópico(s): Horticultural and Viticultural Research
2008 - International Society for Horticultural Science | Acta Horticulturae
In the second half of the 1970s, following the so-called ‘Carnation Revolution’ and when a global wave of privatisations started, the Portuguese government nationalised most of the companies listed on the Lisbon Exchange. A few years later the shareholders of nationalised companies were paid indemnities. The nationalisations radically changed the Portuguese corporate scene and led to very important wealth transfers. Contrary to what is usually assumed, we conclude that this transfer was detrimental ...
Tópico(s): Italy: Economic History and Contemporary Issues
2011 - Cambridge University Press | Financial History Review
Miguel Alpalhão, Joana Antunes, Ana Isabel Gouveia, Rita Travassos, Leonor Lopes, Maria Sanches, Ana Pinto, Bruno Rodrigues, Susana Calado, João Ferreira, Paulo Filipe,
No conflict of interests to report for any of the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Tópico(s): Pharmaceutical studies and practices
2018 - Wiley | Dermatologic Therapy
Tópico(s): Canadian Identity and History
1981 - Laval University Press | Recherches sociographiques
Tópico(s): Urban Development and Societal Issues
2018 - Coimbra University Press | Revista de Estudos Literários
O presente livro surge no âmbito do Projeto Diálogos Quinhentistas (2010-2013), desenvolvido no Centro de Estudos sobre o Imaginário Literário (CEIL), da Faculdade de Ciências Sociais da Universidade Nova de Lisboa, agora integrado no Instituto de Estudos de Literatura e Tradição, da mesma instituição.
Tópico(s): Cultural, Media, and Literary Studies
2019 - Coimbra University Press | Revista de estudos literários
Miguel Alpalhão, Joana Antunes, Luís Soares‐de‐Almeida, Teresa Correia, Paulo Filipe,
The authors declare no conflict of interests
Tópico(s): Blood disorders and treatments
2020 - Wiley | Contact Dermatitis