James F. O’Connell, Kristen Hawkes, Nicholas Blurton Jones,
... Juan Gómez-Hernanz, José I. Alonso-Martín, Ana Abrunhosa, Abel Moclán, Ana I. Casado, Marina Vegara-Riquelme, Ana Álvarez-Fernández, ...
Tópico(s): Primate Behavior and Ecology
1988 - University of Chicago Press | Current Anthropology
Ana I. Rodrigues, Eduardo J. Gudiña, Luı́s Abrunhosa, Ana Rita Malheiro, Rui Fernandes, J. A. Teixeira, L. R. Rodrigues,
Aflatoxins are hepatotoxic and carcinogenic fungal secondary metabolites that usually contaminate crops and represent a serious health hazard for humans and animals worldwide. In this work, the effect of rhamnolipids (RLs) produced by Pseudomonas aeruginosa #112 on the growth and aflatoxins production by Aspergillus flavus MUM 17.14 was studied in vitro. At concentrations between 45 and 1500 mg/L, RLs reduced the mycelial growth of A. flavus by 23-40% and the production of aflatoxins by 93.9-99.5%. ...
Tópico(s): Plant Disease Resistance and Genetics
2021 - Elsevier BV | International Journal of Food Microbiology
Philippe E. Ramos, Luı́s Abrunhosa, Ana C. Pinheiro, Miguel A. Cerqueira, Carla Motta, Isabel Castanheira, Maria V. Chandra-Hioe, Jayashree Arcot, J. A. Teixeira, A. A. Vicente,
This study focused on the use of a new system, an alginate | Ɛ-poly-l-lysine | alginate | chitosan microcapsule (APACM), able to immobilize a folate-producing probiotic, Lactococcus lactis ssp. cremoris (LLC), which provides a new approach to the utilization of capsules and probiotics for in situ production of vitamins. LLC is able to produce 95.25 ± 26 μg·L− 1 of folate, during 10 h, and was encapsulated in the APACM. APACM proved its capacity to protect LLC against the harsh conditions of a simulated digestion ...
Tópico(s): Child Nutrition and Feeding Issues
2016 - Elsevier BV | Food Research International
Joana Gonçalves, Inês R. Violante, José Sereno, Ricardo A. Leitão, Ying Cai, Antero Abrunhosa, Ana Paula Silva, Alcino J. Silva, Miguel Castelo‐Branco,
Excitation/inhibition (E/I) imbalance remains a widely discussed hypothesis in autism spectrum disorders (ASD). The presence of such an imbalance may potentially define a therapeutic target for the treatment of cognitive disabilities related to this pathology. Consequently, the study of monogenic disorders related to autism, such as neurofibromatosis type 1 (NF1), represents a promising approach to isolate mechanisms underlying ASD-related cognitive disabilities. However, the NF1 mouse model showed ...
Tópico(s): Neurological disorders and treatments
2017 - BioMed Central | Molecular Autism
Samuel Chiquita, Mário Ribeiro, João Castelhano, Francisco P. M. Oliveira, José Sereno, Marta Batista, Antero Abrunhosa, Ana Catarina Rodrigues‐Neves, Rafael Carecho, Filipa I. Baptista, Catarina A. Gomes, Paula I. Moreira, António Francisco Ambrósio, Miguel Castelo‐Branco,
The understanding of the natural history of Alzheimer's disease (AD) and temporal trajectories of in vivo molecular mechanisms requires longitudinal approaches. A behavioral and multimodal imaging study was performed at 4/8/12 and 16 months of age in a triple transgenic mouse model of AD (3xTg-AD). Behavioral assessment included the open field and novel object recognition tests. Molecular characterization evaluated hippocampal levels of amyloid β (Aβ) and hyperphosphorylated tau. Magnetic resonance ...
Tópico(s): Neuroscience and Neuropharmacology Research
2019 - Oxford University Press | Human Molecular Genetics
Enrique Baquedano, Juan Luís Arsuaga, Alfredo Pérez‐González, César Laplana, Belén Márquez, Rosa Huguet, Sandra Gómez, Lucía Villaescusa, María Ángeles Galindo-Pellicena, Laura Rodríguez, Rebeca García‐González, M.-Cruz Ortega, David Martín‐Perea, Ana Isabel Ortega Martínez, Lucía Hernández-Vivanco, Gonzalo Ruiz-Liso, Juan Gómez-Hernanz, José I. Alonso-Martín, Ana Abrunhosa, Abel Moclán, Ana I. Casado, Marina Vegara-Riquelme, Ana Álvarez-Fernández, Ángel C. Domínguez‐García, Diego J. Álvarez‐Lao, Nuria Garcı́a, Paloma Sevilla, Hugues‐Alexandre Blain, María Blanca Ruiz Zapata, María José Gil García, Adrián Álvarez‐Vena, Teresa Sanz, Rolf Quam, Thomas Higham,
Abstract This work examines the possible behaviour of Neanderthal groups at the Cueva Des-Cubierta (central Spain) via the analysis of the latter’s archaeological assemblage. Alongside evidence of Mousterian lithic industry, Level 3 of the cave infill was found to contain an assemblage of mammalian bone remains dominated by the crania of large ungulates, some associated with small hearths. The scarcity of post-cranial elements, teeth, mandibles and maxillae, along with evidence of anthropogenic modification ...
Tópico(s): Forensic Anthropology and Bioarchaeology Studies
2023 - Nature Portfolio | Nature Human Behaviour
Patrícia Moura e Sá, Ana Abrunhosa,
Abstract The relationship between TQM and innovation is complex. Literature suggests that the role of TQM varies according to the type of innovation we intend to introduce, essentially favouring incremental innovation while possibly being detrimental to radical innovation. The Portuguese footwear industry is dominated by small-to-medium units with a lack of resources to carry out radical innovations. Cases of success identified in the industry clearly show the importance of developing a close relationship ...
Tópico(s): Outsourcing and Supply Chain Management
2007 - Taylor & Francis | Total Quality Management & Business Excellence
Ana Abrunhosa, Patrícia Moura e Sá,
The relationship between total quality management (TQM) and innovation is complex. Literature suggests that conflicting arguments exist and that the impact of TQM on innovation depends both on the specific quality management elements under consideration and on the type of innovation. In this research, our goal is to analyse at what extent the introduction of TQM is indeed supporting innovation in the Portuguese footwear industry. Since this is a mature industry, whose traditional competitive base ...
Tópico(s): Innovation and Knowledge Management
2007 - Elsevier BV | Technovation
Ana Abrunhosa, Telmo Pereira, Belén Márquez, Enrique Baquedano, Juan Luís Arsuaga, Alfredo Pérez‐González,
Tópico(s): Archaeology and ancient environmental studies
2019 - Springer Nature | Archaeological and Anthropological Sciences
Ana Abrunhosa, M. A. Bustillo, Telmo Pereira, Belén Márquez, Alfredo Pérez‐González, Juan Luís Arsuaga, Enrique Baquedano,
Abstract Studying lithic raw material sourcing, processing and distribution is helpful when trying to reconstruct the territory, ecology, and cultural practices of Neanderthal groups. The use of multiple methods in such analyses allows for more refined characterizations to be made, helping to distinguish between materials better than any single method. Although 85% of the raw materials making up the Mousterian assemblage at the Navalmaíllo Rock Shelter (Pinilla del Valle, Madrid Region of Spain) ...
Tópico(s): Geology and Paleoclimatology Research
2020 - Wiley | Geoarchaeology
Marta Sousa, Rui Abrunhosa Gonçalves, Ana Rita Cruz, Andreia de Castro Rodrigues,
Prison officers are the agents that have the most contact with prisoners during imprisonment and are essential for control prisoners at risk. Because of that, it is essential to understand their attitudes towards prisoners who self-harm because their attitudes predispose the behavior in situations of self-harm. Thus, our study aimed to explore the attitudes of prison officers regarding prisoners who self-harm. The results revealed that prison officers did not advocate harsh treatment for self-harming ...
Tópico(s): Criminal Justice and Corrections Analysis
2019 - Elsevier BV | International Journal of Law and Psychiatry
Luı́s Abrunhosa, António Inês, Ana I. Rodrigues, Ana Guimarães, Vânia L. Pereira, Píer Parpot, Arlete Mendes‐Faia, Armando Venâncio,
Lactic acid bacteria (LAB) are a promising solution to reduce exposure to dietary mycotoxins because of the unique mycotoxin decontaminating characteristic of some LAB. Ochratoxin A (OTA) is one of the most prominent mycotoxins found in agricultural commodities. The present work reports on the ability of Pediococcus parvulus strains that were isolated from Douro wines that spontaneously underwent malolactic fermentation to detoxify OTA. These strains were identified and characterised using a polyphasic ...
Tópico(s): Probiotics and Fermented Foods
2014 - Elsevier BV | International Journal of Food Microbiology
Catarina Abrunhosa, Andreia de Castro Rodrigues, Ana Rita Cruz, Rui Abrunhosa Gonçalves, Olga Cunha,
Intimate partner violence (IPV) is a highly prevalent phenomenon worldwide and is considered a severe violation of human rights. Intimate partner homicide (IPH) and attempted intimate partner homicide (AIPH) although less frequent have a severe direct or indirect impact on victims. Despite the vast literature on IPV and IPH, there is still scarce research on AIPH. Thus, this study aimed to analyze whether perpetrators of IPV, IPH, and AIPH differ from each other, as well as to identify the factors ...
Tópico(s): Criminal Justice and Corrections Analysis
2020 - SAGE Publishing | Journal of Interpersonal Violence
Pedro Pechorro, Rui Abrunhosa Gonçalves, João Marôco, Ana Paula Matias Gama, Saul Neves de Jesús, Cristina Nunes,
The objective of the present study was to analyze the role of psychopathic traits in juvenile delinquency. Using a sample of 543 young males from the Juvenile Detention Centers of the Portuguese Ministry of Justice and from schools in the Lisbon region, a group of high psychopathic traits ( n = 281) and a group of low psychopathic traits ( n = 262) were formed based on the Portuguese version of Antisocial Process Screening Device (APSD). Results showed that youths with high psychopathic traits start engaging ...
Tópico(s): Personality Disorders and Psychopathology
2012 - SAGE Publishing | International Journal of Offender Therapy and Comparative Criminology
Produção Nacional
Revisado por pares
Viviane Mendes Abrunhosa, Carolina Pontes Soares, Ana Claudia Batista Possidonio, André Victor Alvarenga, R P B Costa-Félix, Manoel Luís Costa, Cláudia Mermelstein,
Therapeutic ultrasound (TU) has been used for the last 50 y in rehabilitation, including treatment of soft tissues. Ultrasound waves can be employed in two different modes of operation, continuous and pulsed, which produce both thermal and non-thermal effects. Despite the large-scale use of TU, there are few scientific studies on its biologic effects during skeletal muscle differentiation. To better analyze the cellular effects of TU, we decided to follow cells in vitro. The main purpose of this ...
Tópico(s): Microbial Inactivation Methods
2014 - Elsevier BV | Ultrasound in Medicine & Biology
Raquel F.S. Gonçalves, Joana T. Martins, Luı́s Abrunhosa, A. A. Vicente, Ana C. Pinheiro,
This work aimed at evaluating the effects of different emulsifiers on curcumin-loaded nanoemulsions’ behavior during digestion, its safety and absorption, to develop nanoemulsions that provide safety and improved curcumin functionality. Nanoemulsions (NEs) were produced using two bio-based (lecithin (LEC) and rhamnolipids (RHAM)) and one synthetic (Tween®80 (TWE)) emulsifier at similar concentrations. Different NEs were subjected to in vitro digestion. The cytotoxicity and permeability tests were performed ...
Tópico(s): Polysaccharides Composition and Applications
2021 - Multidisciplinary Digital Publishing Institute | Nanomaterials
Raquel F.S. Gonçalves, Joana T. Martins, Luı́s Abrunhosa, João P. Baixinho, Ana A. Matias, A. A. Vicente, Ana C. Pinheiro,
The aim of this study was to evaluate the behavior of different lipid-based nanostructures during in vitro digestion, in particular on curcumin’s bioaccessibility, and to access their potential toxicity. Solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) and nanoemulsions (NE) were submitted to harmonized static in vitro digestion and their cytotoxicity and cellular transport were evaluated using Caco-2 cell line. NE presented the highest curcumin’s bioaccessibility followed by NLC ...
Tópico(s): African Botany and Ecology Studies
2021 - Elsevier BV | Food Research International
Beatriz Lapa, Ana Cristina Gonçalves, Joana Jorge, Raquel Alves, Ana Salomé Pires, Ana Margarida Abrantes, Margarida Coucelo, Antero Abrunhosa, Maria Filomena Botelho, Nascimento Costa, Ana Bela Sarmento‐Ribeiro,
Tópico(s): Epigenetics and DNA Methylation
2020 - Springer Science+Business Media | Medical Oncology
Filipa Abrunhosa, Sílvia Faria, Paula Gomes, Ana Isabel Tomaz, João Costa Pessoa, David Andreu, Margarida Bastos,
The interaction of two hybrid peptides of cecropin A and melittin [CA(1−8)M(1−18) and CA(1−7)M(2−9)] with liposomes was studied by differential scanning calorimetry (DSC), circular dichroism (CD), and quasi-elastic light scattering (QELS). The study was carried out with large unilamellar vesicles (LUVs) of three different lipid compositions: 1,2-dimyristoil-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (DMPG) and a binary mixture of DMPC/DMPG, in a wide range ...
Tópico(s): Biochemical and Structural Characterization
2005 - American Chemical Society | The Journal of Physical Chemistry B
Manuel Santonja, Alfredo Pérez‐González, Javier Baena Preysler, Joaquín Panera, Eduardo Méndez‐Quintas, David Uribelarrea, Martina Demuro, Lee J. Arnold, Ana Abrunhosa, Susana Rubio‐Jara,
In the upper basin of the Guadiana River, especially in the sectors drained by its right-bank tributaries, the Bullaque and Becea rivers, important concentrations of Acheulean and Mousterian industries can be found in a superficial position. These industries have provided series containing tens of thousands of pieces. Deposits in stratigraphic position have also been identified, related to the fluvial terraces of the Guadiana and Jabalón rivers and some tributaries. Within the sector studied, in ...
Tópico(s): Geology and Paleoclimatology Research
2022 - Frontiers Media | Frontiers in Earth Science
Margarida Angélica da Silva Vasconcelos, Essi Viding, Catherine L. Sebastian, Susana Faria, Pedro R. Almeida, Óscar F. Gonçalves, Rui Abrunhosa Gonçalves, Adriana Sampaio, Ana Seara‐Cardoso,
Callous-unemotional (CU) traits observed during childhood and adolescence are thought to be precursors of psychopathic traits in adulthood. Adults with high levels of psychopathic traits typically present antisocial behavior. Such behavior can be indicative of atypical moral processing. Evidence suggests that moral dysfunction in these individuals may stem from a disruption of affective components of moral processing rather than from an inability to compute moral judgments per se . No study to date ...
Tópico(s): Psychology of Moral and Emotional Judgment
2021 - Frontiers Media | Frontiers in Psychiatry
Ana Guimarães, Luı́s Abrunhosa, Lorenzo Pastrana, Miguel A. Cerqueira,
Abstract Edible films and coatings have been extensively studied in recent years due to their unique properties and advantages over more traditional conservation techniques. Edible films and coatings improve shelf life and food quality, by providing a protective barrier against physical and mechanical damage, and by creating a controlled atmosphere and acting as a semipermeable barrier for gases, vapor, and water. Edible films and coatings are produced using naturally derived materials, such as ...
Tópico(s): Meat and Animal Product Quality
2018 - Wiley | Comprehensive Reviews in Food Science and Food Safety
Telma C. Almeida, Rui Abrunhosa Gonçalves, Ana Isabel Sani,
Introduction: Exposure to interparental violence is a type of child maltreatment linked to a higher risk of physical and mental health problems. This research considers the experiences of young Portuguese children exposed to interparental violence. The goal is to explore the associations between interparental conflict in children, their perceptions of conflict properties, threat, self-blame, and the relationship with their parents. Method: The research protocol was applied to 888 Portuguese children ...
Tópico(s): Homicide, Infanticide, and Child Abuse
2022 - CIG Media Group | Suma Psicológica
V. Mareco, L. Bujor, André Abrunhosa-Branquinho, Miguel Reis Ferreira, Tiago Ribeiro, Ana Luísa Vasconcelos, Cidalina Reis Ferreira, Marília Jorge,
To report the experience and the outcomes of interstitial high-dose-rate (HDR) brachytherapy (BT) of eyelid skin cancer at the Department of Radiotherapy of Hospital de Santa Maria in Lisbon.Seventeen patients (pts; mean age, 73.75 years) who underwent eyelid interstitial HDR BT with an (192)Ir source between January 2011 and February 2013 were analyzed. Lesions were basal (94%) and squamous (6%) cell carcinomas, on lower (88%) or upper (6%) eyelids, and on inner canthus (6%). T-stage was Tis (6%), T1 (46%), ...
Tópico(s): Ear and Head Tumors
2015 - Elsevier BV | Brachytherapy
Ricardo Martins, Francisco P. M. Oliveira, Fradique Moreira, Ana Paula Moreira, Antero Abrunhosa, Cristina Januário, Miguel Castelo‐Branco,
Objective.To explore the viability of developing a computer-aided diagnostic system for Parkinsonian syndromes using dynamic [11C]raclopride positron emission tomography (PET) and T1-weighted magnetic resonance imaging (MRI) data.Approach.The biological heterogeneity of Parkinsonian syndromes renders their statistical classification a challenge. The unique combination of structural and molecular imaging data allowed different classifier designs to be tested. Datasets from dynamic [11C]raclopride PET ...
Tópico(s): Advanced MRI Techniques and Applications
2021 - IOP Publishing | Journal of Neural Engineering
Ana Abrunhosa, Belén Márquez, Enrique Baquedano, Nuno Bicho, Alfredo Pérez‐González, Juan Luís Arsuaga,
This article presents the PhD project under the supervision of Nuno Bicho and Enrique Baquedano, which aims to study the origin of raw materials from the Mousterian lithic sets of the Calvero de la Higuera sites. At this first stage of the project the main objective is the determination and characterization of the raw materials present at the sites.
Tópico(s): Archaeological and Historical Studies
2014 - | Estudos do Quaternário / Quaternary Studies
Francisco P. M. Oliveira, Antoine Leuzy, João Castelhano, Konstantinos Chiotis, Steen Gregers Hasselbalch, Juha O. Rinne, Alexandre de Mendonça, Markus Otto, Alberto Lleó, Isabel Santana, Jarkko Johansson, Sarah Anderl‐Straub, Christine A. F. Von Arnim, Ambros J. Beer, Rafael Blesa, Juan Fortea, Sanna‐Kaisa Herukka, Erik Portelius, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Ana Paula Moreira, Antero Abrunhosa, Agneta Nordberg, Miguel Castelo‐Branco,
Positron emission tomography (PET) neuroimaging with the Pittsburgh Compound_B (PiB) is widely used to assess amyloid plaque burden. Standard quantification approaches normalize PiB-PET by mean cerebellar gray matter uptake. Previous studies suggested similar pons and white-matter uptake in Alzheimer's disease (AD) and healthy controls (HC), but lack exhaustive comparison of normalization across the three regions, with data-driven diagnostic classification. We aimed to compare the impact of distinct ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2018 - Elsevier BV | NeuroImage Clinical
Olga Cunha, Maria Manuela Peixoto, Ana Rita Cruz, Rui Abrunhosa Gonçalves,
This study aimed to analyze the fit of the four-factor model of the 29-item and 12-item Buss-Perry Aggression Questionnaire (BPAQ) on a sample of Portuguese male perpetrators of intimate partner violence (IPV; N = 279) and to test the measurement invariance between sample type (forensic and non-forensic) and sentence type (prison and community). Confirmatory factor analysis (CFA) did not support the four-factor model of the BPAQ 29-item version. The four-factor model of the BPAQ–short form (BPAQ-SF) showed ...
Tópico(s): Sexual Assault and Victimization Studies
2021 - SAGE Publishing | Criminal Justice and Behavior
Lília Jorge, Ricardo Martins, Nádia Canário, Ana Carolina Xavier, Antero Abrunhosa, Isabel Santana, Miguel Castelo‐Branco,
It has been proposed that amyloid-β (Aβ) plays a causal role in Alzheimer's disease (AD) by triggering a series of pathologic events-possibly including neuroinflammation-which culminate in progressive brain atrophy. However, the interplay between the two pathological molecular events and how both are associated with neurodegeneration is still unclear.We aimed to estimate the spatial inter-relationship between neurodegeneration, neuroinflammation and Aβ deposition in a cohort of 20 mild AD patients ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2021 - IOS Press | Journal of Alzheimer s Disease
Andreia de Castro Rodrigues, Olga Cunha, Jorge Quintas, Rui Abrunhosa Gonçalves, Ana Sacau,
Abstract This study examines judges’ value judgments on their remarks during sentence pronouncements. We performed a content analysis of 93 sentence pronouncements from the 13 judges from a Portuguese criminal court. Within these discourses, 299 discourse units were codified as judges’ value judgments, that is, personal contents beyond strict legal issues. From these 299, 107 were recommendations (comprehending advice to change, to not reoffend, to rethink life, and action instructions), and 192 ...
Tópico(s): Law, Economics, and Judicial Systems
2023 - Springer Science+Business Media | Crime Law and Social Change