Limpar
7.352 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Georgia Salanti, Natalie Peter, Thomy Tonia, Alexander Holloway, Ian R. White, Leila Darwish, Nicola Low, Matthias Egger, Andreas D. Haas, Seena Fazel, Ronald C. Kessler, Helen Herrman, Christian Kieling, Dominique J.‐F. de Quervain, Simone N. Vigod, Vikram Patel, Tianjing Li, Pim Cuijpers, Andrea Cipriani, Toshi A. Furukawa, Stefan Leucht, Abdulkadir Usman Sambo, Akira Onishi, Akira Sato, Alessandro Rodolico, Ana Cristina de Oliveira Solis, Anastasia Antoniou, Angelika Kapfhammer, Anna Ceraso, Aoife O’Mahony, Aurélie M. Lasserre, Aziz Mert Ipekci, Carmen Concerto, Caroline Zangani, Chinonso Nwamaka Igwesi-Chidobe, C. Diehm, Dicle Dilay Demir, Dongfang Wang, Edoardo G. Ostinelli, Ethan Sahker, Gabriel Henrique Beraldi, Gamze Erzın, Harrison Nelson, Hélio Elkis, Hissei Imai, Hui Wu, Ilias Kamitsis, Ioannis Filis, Ioannis Michopoulos, Irene Bighelli, James S. W. Hong, Javier Ballesteros, Katharine Smith, Kazufumi Yoshida, Kenji Omae, Marialena Trivella, Masafumi Tada, Matthias A. Reinhard, Michael J. Ostacher, Monika Müller, Nathalia González-Jaramillo, Panagiotis Ferentinos, Rie Toyomoto, Samuele Cortese, Sanae Kishimoto, Sergio A. Covarrubias-Castillo, Spyridon Siafis, Trevor Thompson, Vasilios Karageorgiou, Virginia Chiocchia, Yikang Zhu, Yukiko Honda, Abdulkadir Usman Sambo, Akira Onishi, Akira Sato, Alessandro Rodolico, Ana Cristina de Oliveira Solis, Anastasia Antoniou, Angelika Kapfhammer, Anna Ceraso, Aoife O’Mahony, Aurélie M. Lasserre, Aziz Mert Ipekci, Carmen Concerto, Caroline Zangani, Chinonso Nwamaka Igwesi-Chidobe, C. Diehm, Dicle Dilay Demir, Dongfang Wang, Edoardo G. Ostinelli, Ethan Sahker, Gabriel Henrique Beraldi, Gamze Erzın, Harrison Nelson, Hélio Elkis, Hissei Imai, Hui Wu, Ilias Kamitsis, Ioannis Filis, Ioannis Michopoulos, Irene Bighelli, James S. W. Hong, Javier Ballesteros, Katharine Smith, Kazufumi Yoshida, Kenji Omae, Marialena Trivella, Masafumi Tada, Matthias A. Reinhard, Michael J. Ostacher, Monika Müller, Nathalia González-Jaramillo, Panagiotis Ferentinos, Rie Toyomoto, Samuele Cortese, Sanae Kishimoto, Sergio A. Covarrubias-Castillo, Spyridon Siafis, Trevor Thompson, Vasilios Karageorgiou, Virginia Chiocchia, Yikang Zhu, Yukiko Honda,

Background: To what extent the COVID-19 pandemic and its containment measures influenced mental health in the general population is still unclear. Purpose: To assess the trajectory of mental health symptoms during the first year of the pandemic and examine dose–response relations with characteristics of the pandemic and its containment. Data Sources: Relevant articles were identified from the living evidence database of the COVID-19 Open Access Project, which indexes COVID-19–related publications ...

Tópico(s): Health and Well-being Studies

2022 - American College of Physicians | Annals of Internal Medicine

Artigo Acesso aberto

Sofía Lerche Vieira, Eloísa Maia Vidal,

... handle/10482/1845. Acesso em: 27 out. 2018.OLIVEIRA, Ana Cristina Prado de. Gestão, liderança e clima escolar. Curitiba: Appris, 2018.OLIVEIRA, Ana Cristina Prado de; CARVALHO, Cynthia Paes de. Gestão escolar, liderança do ... 23-e230015.pdf. Acesso em: 19 ago. 2018.OLIVEIRA, Ana Cristina Prado de; WALDHELM, Andrea Paula Souza. Liderança do diretor, clima ...

Tópico(s): Social and Political Issues

2019 - UNIVERSIDADE FEDERAL DE SÃO CARLOS | Revista Eletrônica de Educação

Artigo Acesso aberto Brasil Produção Nacional

Breynner Ricardo de Oliveira, Ana Cristina Prado de Oliveira, Gláucia Maria dos Santos Jorge, Jianne Ines Fialho Coelho,

O artigo analisa a implementação da educação remota na Rede Estadual de Minas Gerais por meio do “Regime de Estudo não Presencial” (REANP) em tempos de pandemia. A pesquisa se deu em três fases: levantamento dos marcos institucionais do programa; análise dos eixos de ação e dos comentários nos canais de comunicação disponibilizados pela Secretaria de Educação (SEE). Os dados foram organizados em sete dimensões: (1) o acesso ao programa; (2) a receptividade ao REANP; (3) percepções sobre o aplicativo e ...

Tópico(s): Education Pedagogy and Practices

2021 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Revista Ibero-Americana de Estudos em Educação

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Sérgio Henrique Silva, Isabelle Cristina Oliveira Neves, Ana Cristina Freitas de Oliveira Meira, Ana Cláudia Silveira Alexandre, Natália Leite Oliveira, Jaime Vilela de Resende,

Mucilage extracts from the leaves (ML) and fruits (MFR) of ora-pro-nobis were used as stabilizing agent with a mixture of carrageenans (MIX) at different concentrations for Petit Suisse cheese production. The texture, syneresis, and viscosity profiles were analyzed in fresh samples and in samples rehydrated after freeze-drying. The textural properties analyzed in the fresh samples increased as the mucilage concentrations of (ML), (MFR) and (MIX) increased. After rehydration, the values of the textural ...

Tópico(s): Proteins in Food Systems

2021 - Elsevier BV | LWT

Revisão Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Cristina de Oliveira e Silva, Ana Maria de Almeida, Maria Eliane Moreira Freire, Jordana de Almeida Nogueira, Elucir Gir, Wynne Pereira Nogueira,

ABSTRACT Objective: to identify scientific evidence on the effectiveness of using cloth masks as safe protectors against COVID-19. Method: an integrative review of articles available in full obtained at PubMed, CINAHL, and Web of Science. Controlled, non-controlled descriptors and keywords such as “mask”, “home-made” and “cloth” or “cotton” and “infection control” or “infection prevention” were used. Results: thirty-eight articles were selected; of these, seven studies made up the sample. Evidence shows ...

Tópico(s): Climate Change and Health Impacts

2020 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

David R. da Rocha, Jorge André Matias Martins, Maurício Fraga van Tilburg, Rodrigo Vasconcelos de Oliveira, Frederico Bruno Mendes Batista Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, Renato de Azevedo Moreira, Aírton Alencar de Araújo, Arlindo A. Moura,

The present study evaluated the effects of heat stress on the ram seminal plasma proteome. Six Morada Nova rams were scrotal insulated for 8 days. Scrotal circumference, sperm parameters, and seminal fluid proteins were evaluated before (Day 0) and twice during scrotal insulation (Days 4 and 8), and weekly until semen parameters returned to preinsulation values (normal). Seminal proteins were analyzed by two-dimensional SDS-PAGE and mass spectrometry. Scrotal circumference decreased from 30 ± 0.4 cm ...

Tópico(s): Hormonal and reproductive studies

2015 - Elsevier BV | Theriogenology

Artigo

Clarissa Rosa, Bruno R. Ribeiro, Vanesa Bejarano Alegre, Fernando Henrique Puertas, Adriana Bocchiglieri, Adriana Loeser dos Santos Barbosa, Adriano G. Chiarello, Adriano Pereira Paglia, Adriele Aparecida Pereira, Adryelle Francisca de Souza Moreira, Agnis Cristiane de Souza, A. O. Pellegrin, Ailín Gatica, Akyllan Zoppi Medeiro, Alan Deivid Pereira, Alan Gerhardt Braz, Alberto Yanosky, Alejandro E. J. Valenzuela, Alessandra Bertassoni, Alessandra dos Santos Venturini do Prado, Alessandra Ferreira Dales Nava, Alessandro Rocha, Alex Augusto Abreu Bovo, Alex Bager, Alexandra Cravino, Alexandra S. Pires, Alexandre Camargo Martensen, Alexandre Filippini, Alexandre Reis Percequillo, Alexandre Vogliotti, Alexsander Zamorano Antunes, Aline Cristina Leite de Oliveira, Allan Jefferson da Silva de Oliveira, Allison L. Devlin, Almir de Paula, Aluane Silva Ferreira, Alvaro García‐Olaechea, Amanda L. Subalusky, Amadeo Sánchez, Ana Carla Medeiros Morato de Aquino, Ana Carolina Srbek‐Araujo, Amane Paldês Gonçales, Ana Caroline L. Araújo, A. Cecilia Gozzi, Ana Cecilia Ochoa, Ana Cristina Mendes de Oliveira, Ana Cristyna Reis Lacerda, Ana Karina de Francisco, Ana Maria de Oliveira Paschoal, Ana Paula Nascimento Gomes, Ana Paula Potrich, Ana Priscila Medeiros Olímpio, Ana Pozuelos Rojas, Ana Yoko Ykeuti Meiga, Anah Tereza de Almeida Jácomo, Analice Maria Calaça, Anderson Feijó, Anderson Pagoto, André Sebastián Borja-Chiriboga, André Chein Alonso, André Felipe Barreto‐Lima, André Monnerat Lanna, André Luís Luza, André Restel Camilo, André Tavares, André Valle Nunes, Andreas Kindel, Andrés de Miguel, Andressa Gatti, Andrezza Bellotto Nobre, Anielise da Conceição Campêlo, Anna Carolina Figueiredo de Albuquerque, J. Antonio de la Torre, Antonio M. Mangione, Antônio Rossano Mendes Pontes, Arthur Soares Fernandes, Artur Luiz de Almeida Felício, Átilla Colombo Ferreguetti, Arlei Marcili, Augusto João Piratelli, Ariel Guilherme Santos do Nascimento, Áureo Banhos, Beatris Felipe Rosa, Beatriz Azevedo Cezila, Benoı̂t de Thoisy, Bianca Ingberman, Bianca Köhler, Bianca Cruz Morais, Bibiana Gómez‐Valencia, Bruna Bertagni de Camargo, Bruna M. Bezerra, Bruna Tamasauskas, Bruno Augusto Torres Parahyba Campos, Bruno Busnello Kubiak, Bruno H. Saranholi, Bruno Kazuo Nakagawa, Bruno Leles, Burton K. Lim, Calebe Pereira Mendes, Camila Alvez Islas, Camila Aoki, Camila Cantagallo Devids, Camila Pugliesi De Figueiredo, Camila Matias Goes de Abreu, Camila Raquel Silva Oliveira, Camila Righetto Cassano, Camile Lugarini, Carin Caputo, Carla C. Gestich, Carla Denise Tedesco, Carla Fabiane de Vera y Conde, Carla Grasiele Zanin Hegel, Carlos Benhur Kasper, Carlos De Angelo, Carlos Eduardo Viveiros Grelle, Carlos Eduardo Fragoso, Carlos Eduardo Lustosa Esbérard, Carlos Frederico Duarte Rocha, Carlos Eduardo Verona, Carlos Henrique Salvador, Carlos Leonardo Vieira, Carlos Roberto Abrahão, Carlos Rodrigo Brocardo, Carolline Zatta Fieker, Caryne Braga, Catalina Sánchez‐Lalinde, Cecília Bueno, Cássia Yumi Ikuta, Cecília Licarião Luna, César Cestári, Christine Del Vechio Koike, Christoph Knogge, Christopher B. Anderson, Cindy M. Hurtado, Cintia Ferreira Antunes de Oliveira, Cintia Gisele Tellaeche, Clarice Silva Cesário, Claudia Guimarães Costa, Claudia Zukeran Kanda, Sebastián Andrés Costa, Cristiana Simão Seixas, Cristiano Trapé Trinca, Cristina Fabiola López‐Fuerte, Cristina Jaques da Cunha, Cynthia Doutel Ribas, Cyntia Cavalcante Santos, Daiane Buscariol, Daiane Carreira, Daiane Chaves do Nascimento, Danianderson Rodrigues Carvalho, Daniel da Silva Ferraz, Daniel Galiano, Daniel Henrique Homem, Daniel Jesús‐Espinosa, Daniela Aparecida Savariz Bôlla, Daniele Janina Moreno, Danielle de Oliveira Moreira, Danielle Leal Ramos, Danilo Angelucci de Amorim, Darci Moraes Barros‐Battesti, David Echeverri Lopez, Davi Castro Tavares, David M. Post, Dayvid Rodrigues Couto, Dennis Nogarolli Patrocínio, Diana Letícia Kruger Pacheco Carvalho, Diego Afonso Silva, Diego Córdoba, Diego Queirolo, Diego� Varela, Dilmar Alberto Gonçalves de Oliveira, Diogo Cavenague Casanova, Douglas de Matos Dias, Douglas Machado da Silva, Eder Barbier, Edgar Federico Rivadeneira, Eduardo Roberto Alexandrino, Eduardo Carrano, Eduardo Marques Santos, Eduardo Martins Venticinque, Edwin L. Hernández-Pérez, Egberto da Fonseca Casazza, Elizabeth P. Anderson, Elmary da Costa Fraga, Elson Fernandes de Lima, Elvira D’Bastiani, Emerson Monteiro Vieira, Emiliano Guijosa‐Guadarrama, Enrique M. González, Erica Vanessa Maggiorini, Erick Francisco Silva de Aguiar, Erik Daniel Martínez‐Nambo, Érika Paula Castro, Erika de la Peña‐Cuéllar, Ezequiel Pedó, Fabiana Cristina Silveira Alves de Melo, Fabiana Lopes Rocha, Fabiana Luques Fonseca, Fabiane Girardi, Fabiano Rodrigues de Melo, Fábio de Oliveira Roque, Fabíola Keesen, Felipe Bortolotto Peters, Felipe Moreli Fantacini, Felipe Pedrosa, Felipe Pessoa da Silva, Felipe Vélez‐García, Fernanda Delborgo Abra, Fernanda Cavalcanti de Azevedo, Fernanda Guedes da Silva, Fernanda Maria Neri, Fernanda Zimmermann Teixeira, Fernando Antonio dos Santos Fernandez, Fernando Carvalho, Fernandode Camargo Passos, Fernando de Castro Jacinavicius, Fernando Ferreira, Fernando Ferreira de Pinho, Fernando Gonçalves, Fernando Ibanez Martins, Fernando Lima, Fernando M. Contreras‐Moreno, Fernando Silvério Ribeiro, Fernando Rodrigo Tortato, F.M.PATEL F.M.PATEL, Flavia Caruso, Flávia Pereira Tirelli, Flávio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francesca Belem Lopes Palmeira, Francisco Grotta‐Neto, Francisco Homem Gabriel, Franco L. Souza, Francys E. da Veiga da Costa, Gabriel Lima Aguiar, Frederico Gemesio Lemos, Gabriel Shimokawa Magezi, Gabriel Ferreira Vianna Di Panigai, Gabriel Selbach Hofmann, Gabriela Heliodoro, Gabriela Rosa Graviola, Gabrielle Beca, Gabrielle Ribeiro de Andrade, Germán Jiménez, Gabriela Teixeira Duarte, Geruza Leal Melo, Geverson Luiz Dierings, Gilberto Sabino‐Santos, Geovana Linhares de Oliveira, Gindomar Gomes Santana, Giordano Ciocheti, Gisele Lamberti Zanirato, Giselle Bastos Alves, Graziele Oliveira Batista, Greici Maia Behling, Guilherme Braga Ferreira, Guilherme Casoni da Rocha, Gisele Lessa, Guilherme Mourão, Gustavo A. Marás, Gustavo Alves da Costa Toledo, Gustavo Gonsioroski, Gustavo Rodrigues Canale, Karl‐Ludwig Schuchmann, Harley Sebastião, Helena Alves do Prado, Helena Godoy Bergallo, Helio Secco, Henrique Llacer Roig, Henrique Rajão, Henrique Santiago Alberto Carlos, Herbert O. B. Duarte, Hiago Ermenegildo, Hilda Fátima Jesus Pena, Hilton Entringer, Hipólito Ferreira Paulino Neto, Hudson de Macedo Lemos, Hugo del Castillo, Hugo Fernandes‐Ferreira, Hugo Ignacio Coitiño Banquero, Ignacio Roesler, Igor Kintopp Ribeiro, Igor Pfeifer Coelho, Ingrid M. S. Lima, Isabel Muniz Bechara, Isabel Salgueiro Lermen, Isac Mella-Méndez, Gabriela Schuck, Isadora Beraldi Esperandio, Ita de Oliveria Silva, Ítalo Mourthé, Igor Oliveira, Itiberê P. Bernardi, Jacqueline R. Miller, Jader Marinho‐Filho, Jairo José Zocche,

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or ...

Wiley

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Valzimeire do Nascimento de Oliveira, Abelardo Barbosa Moreira Lima Neto, Maurício Fraga van Tilburg, Ana Cristina de Oliveira Monteiro‐Moreira, Marina Duarte Pinto Lobo, Davide Rondina, Virgínia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Renan Magalhães Montenegro, Maria Izabel Florindo Guedes,

Purpose: Type 1 diabetes mellitus (DM1) is one of the most common chronic diseases observed during childhood. The incidence of DM1 is increasing worldwide, and there is currently no way to prevent or delay the onset or to cure the disease. Most diseases, including diabetes, stem from abnormalities in the functioning of proteins, and some studies have reported the expression of protein variation to be involved in the development of DM1. Thus, the aim of this study was to investigate the differential ...

Tópico(s): Metabolism, Diabetes, and Cancer

2018 - Dove Medical Press | Diabetes Metabolic Syndrome and Obesity

Artigo

Paloma Marques Santos, Adriana Bocchiglieri, Adriano G. Chiarello, Adriano Pereira Paglia, Adryelle Francisca de Souza Moreira, Agnis Cristiane de Souza, Agustín M. Abba, Agustín Paviolo, Ailín Gatica, Akyllan Zoppi Medeiro, Alan N Costa, Alberto Gonzalez Gallina, Alberto Yanosky, Alejandro Jesús, Alessandra Bertassoni, Alessandro Rocha, Alex Augusto Abreu Bovo, Alex Bager, Alexandra Cravino Mol, Alexandre Camargo Martensen, Alexandre Casagrande Faustino, Alexandre Martins Costa Lopes, Alexandre Reis Percequillo, Alexandre Vogliotti, Alexine Keuroghlian, Alicia de la Colina, Allison L. Devlin, Alvaro García‐Olaechea, Amadeo Sánchez, Ana Carolina Srbek‐Araujo, Ana Cecilia Ochoa, Ana Cristina Mendes de Oliveira, Ana Cristyna Reis Lacerda, Ana Kellen Nogueira Campelo, Ana Maria de Oliveira Paschoal, Ana Raíssa Cunha Costa, Ana Yoko Ykeuti Meiga, Anamélia de Souza Jesus, Anderson Feijó, André Hirsch, André Luiz Ferreira da Silva, André Luís Botelho, André Luis Regolin, André Monnerat Lanna, André Valle Nunes, Andreas Kindel, Andréia Magro Moraes, Andressa Gatti, Andrew J. Noss, Andrezza Bellotto Nobre, Anelise Montanarin, Ângela Camila Deffaci, Anna Carolina Figueiredo de Albuquerque, Alice Kalisz de Oliveira, Antonio M. Mangione, Antônio Rossano Mendes Pontes, Ariane Teixeira Bertoldi, Armando Muniz Calouro, Arnaud Léonard Jean Desbiez, Arthur Soares Fernandes, Átilla Colombo Ferreguetti, Maria Augusta Andrade da Silva, Bárbara Zimbres, Beatriz Fernandes Lima Luciano, Benoı̂t de Thoisy, Bernardo Brandão Niebuhr, Bernardo Papi, Bibiana Gómez‐Valencia, Bráulio Almeida Santos, Breno C. Lima, Bruna Gomes Oliveira, Bruna Silva Santos, Bruno Augusto Torres Parahyba Campos, Bruno Leles, Bruno Rodrigo de Albuquerque França, Burton K. Lim, Caetano Troncoso Oliveira, Camila Cantagallo Devids, Camila Clozato Lara, Camila S. Lima, Carla C. Gestich, Carla Danielle de Melo‐Soares, Carlos A. Peres, Carlos Benhur Kasper, Carlos Candia‐Gallardo, Carlos De Angelo, Carlos Eduardo Fragoso, Carlos Henrique de Freitas, Carlos Henrique Salvador, Carlos Rodrigo Brocardo, Carolina Depolito Melo, Caroline Leuchtenberger, Caryne Braga, Catalina Sánchez‐Lalinde, Cecília Bueno, Cecília Licarião Luna, César Rojano, Cindy M. Hurtado, C. Santos, Cintia Gisele Tellaeche, Clarissa Rosa, Cláudia Bueno de Campos, Cláudia Regina da Silva, Claudia Zukeran Kanda, Clinton N. Jenkins, Colleen M. McDonough, Cristiano Trapé Trinca, Cristina Jaques da Cunha, Cynthia Elisa Widmer, Cyntia Cavalcante Santos, Daiane Buscariol, Daiane Carreira, Danianderson Rodrigues Carvalho, Daniel da Silva Ferraz, Daniel Casali, Daniel H. Thornton, Daniela Rodrigues Vasconcellos, Daniele Cristina Barcelos, Danielle D. Brown, Danielle Leal Ramos, Danielle de Oliveira Moreira, Débora Regina Yogui, Deborah Faria, Dênis A. Sana, Donatella Mattia, Denison José Henz, Diana Friedeberg, Diana Letícia Kruger Pacheco Carvalho, Diego Astúa, Diego Queirolo, Diego� Varela, Donald P. Eaton, Douglas de Matos Dias, Edgar Federico Rivadeneira, Ednaldo Cândido Rocha, Edson F. Abreu, Eduardo Carrano, Eduardo Marques Santos, Eleonore Zulnara Freire Setz, Elildo A. R. Carvalho, Elisandra de Almeida Chiquito, Elizandra M. Cardoso, Eloísa Neves Mendonça, Elvira D’Bastiani, Emerson Monteiro Vieira, Emiliano Esterci Ramalho, Emiliano Guijosa‐Guadarrama, Enrique M. González, Erica Vanessa Maggiorini, Erich Arnold Fischer, Erick Francisco Silva de Aguiar, Érika Paula Castro, Erika de la Peña‐Cuéllar, Ernesto B. Viveiros de Castro, Evelyn Britez, Ezequiel Vanderhoeven, Ezequiel Pedó, Fabiana Lopes Rocha, Fabiane Girardi, Fábio de Oliveira Roque, Fábio Dias Mazim, Fábio de Barros, Felipe Martello, Felipe Moreli Fantacini, Felipe Pedrosa, Felipe Bortolotto Peters, Fernanda Delborgo Abra, Fernanda Cavalcanti de Azevedo, Fernanda Santos, Fernanda Guedes da Silva, Fernanda Zimmermann Teixeira, Fernando A. Perini, Fernando C. Passos, Fernando Carvalho, Fernando César Cascelli de Azevedo, Fernando Ferreira de Pinho, Fernando Gonçalves, Fernando Lima, Fernando M. Contreras‐Moreno, Fernando Pedroni, Fernando Rodrigo Tortato, Filipe Pereira Rego Santos, Flavia Caruso, Flávia Pereira Tirelli, Flávia Regina Miranda, Flávio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francesca Belem Lopes Palmeira, Franciane Almeida da Silva, Francisco Grotta‐Neto, Franco L. Souza, Francys E. da Veiga da Costa, Freddy Pérez-Garduza, Frédéric Delsuc, Frederico Gemesio Lemos, Fredy Ramírez Pinto, Gabriel Boaglio, Gabriel Fávero Massocato, Gabriel Preuss, Gabriel Selbach Hofmann, Gabriel Lima Aguiar, Gabriela Schuck de Oliveira, Gabriela Teixeira Duarte, Gabrielle Beca, Gastón Andrés Fernandez Giné, Graziele Oliveira Batista, Guillermo E. Gil, Gustavo Gonsioroski, Helio Secco, Hugo Reis Medeiros, Igor Pfeifer Coelho, Ingridi Camboim Franceschi, Itiberê P. Bernardi, J. Antonio de la Torre, Jairo José Zocche, Jardel Brandão Seibert, Jéssica Caroline de Faria Falcão, Jéssica Helena Mangueira Dias, Joana Zorzal Nodari, João Alves de Oliveira, João Gabriel Ribeiro Giovanelli, João Paulo Pandini Favoretti, John Polisar, Jonas Sponchiado, Jorge José Cherem, José Fernando Moreira-Ramírez, José Júlio de Toledo, José Maurício Barbanti Duarte, José Roberto de Matos, Juan Pablo Arrabal, Júlia Emi de Faria Oshima, Juliana Fernandes Ribeiro, Juliano André Bogoni, Julio Chacón-Pacheco, Karl‐Ludwig Schuchmann, Kátia Maria Paschoaletto Micchi de Barros Ferraz, Laís dos Santos Everton, Larissa L. Bailey, Larissa Oliveira Gonçalves, Laury Cullen, Layla Reis de Andrade, Leonardo Carreira Trevelin, Lilian Bonjorne, Lívia de Almeida Rodrigues, Lucas Leuzinger, Lucas Neves Perillo, Luciana Souza Araújo, Ludmila Hufnagel, Ludmilla Oliveira Ribeiro, Luis Renato Rezende Bernardo, Luiz Gustavo Rodrigues Oliveira‐Santos, Luiz H. Varzinczak, Luiz Henrique Medeiros Borges, Luiza Neves Guimarães, Lydia Möcklinghoff, Marcela Álvares Oliveira, Marcelo Magioli, Márcia Maria de Assis Jardim, Márcio Leite de Oliveira, Marcos Adriano Tortato, Marcos Dums, María Eugenia Iezzi, María João Ramos Pereira, María Luisa S. P. Jorge, Maria Santina de Castro Morini, Mariana Landis, Mariana Sampaio Xavier, Marília A. S. Barros, Marina Lima da Silva, Marina Rivero, Marina Zanin, Marinêz Isaac Marques, Mário Henrique Alves, Mario S. Di Bitetti, Martín Roberto Del Valle Alvarez, Maurício Eduardo Graipel, Maurício Neves Godoi, Maximiliano Augusto Benedetti, Mayara Guimarães Beltrão, Miguel Coutinho Moretta Monteiro, Milton José de Paula, Miriam Lúcia Lages Perilli, Murillo Prado da Silva, Nacho Villar, Natasha Moraes de Albuquerque, Nathália Fernandes Canassa, Newton Mota Filho, Nicole da Rosa Oliveira, Nielson Pasqualotto, Nilton C. Cáceres, Nina Attias, Marina Ochoa Favarini, Otávio Santi Ribeiro, Pablo Rodrigues Gonçalves, Patrício Adriano da Rocha, Paula Alves Condé,

Xenarthrans-anteaters, sloths, and armadillos-have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths. Our data set includes the families Chlamyphoridae ( ...

Wiley

Artigo Brasil Produção Nacional Revisado por pares

Cléverson D.T. Freitas, Carolina A. Viana, Ilka M. Vasconcelos, Frederico B. B. Moreno, José Vitor Lima‐Filho, Hermógenes David de Oliveira, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro‐Moreira, Márcio V. Ramos,

Chitinases (EC 3.2.1.14) found in the latex of Calotropis procera (Ait) R. Br. were studied. The proteins were homogeneously obtained after two ion exchange chromatography steps. Most proteins were identified individually in 15 spots on 2-D gel electrophoresis with isoelectric points ranging from 4.6 to 6.0 and molecular masses extending from 27 to 30 kDa. Additionally, 66 kDa proteins were identified as chitinases in SDS-PAGE. Their identities were further confirmed by mass spectrometry (MS) analysis ...

Tópico(s): Studies on Chitinases and Chitosanases

2016 - Elsevier BV | Plant Physiology and Biochemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Antônio José Rocha, Bruno Lopes de Sousa, Matheus S. Girão, Ito L. Barroso-Neto, José E. Monteiro-Júnior, José T.A. Oliveira, Celso Shiniti Nagano, Rômulo Farias Carneiro, Ana Cristina de Oliveira Monteiro‐Moreira, B.A.M. Rocha, V. N. Freire, Thalles B. Grangeiro,

Vicilins are 7S globulins which constitute the major seed storage proteins in leguminous species. Variant vicilins showing differential binding affinities for chitin have been implicated in the resistance and susceptibility of cowpea to the bruchid Callosobruchus maculatus. These proteins are members of the cupin superfamily, which includes a wide variety of enzymes and non-catalytic seed storage proteins. The cupin fold does not share similarity with any known chitin-biding domain. Therefore, it ...

Tópico(s): Genetic and Environmental Crop Studies

2018 - Elsevier BV | International Journal of Biological Macromolecules

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Juliana Pontes Soares, Sheila Araújo Teles, Karlla Antonieta Amorim Caetano, Thaynara Ferreira de Amorim, Maria Eliane Moreira Freire, Jordana de Almeida Nogueira, Brunna Rodrigues de Oliveira, Oriana Deyze Correia Paiva Leadebal, Patrí­cia da Silva Araújo, Ana Cristina de Oliveira e Silva,

Objective: to estimate the prevalence of Sexually Transmitted Infections (STIs) and associated factors in sugarcane cutters. Method: a cross-sectional, analytical study with 937 sugarcane cutters from Paraíba and Goiás, states of Brazil, respectively. An outcome variable was the positive results in some rapid tests for HIV, syphilis, hepatitis B and C. Bivariate and multiple analyses were performed to identify the association between these infections and sociodemographic and behavioral variables. ...

Tópico(s): Microfinance and Financial Inclusion

2020 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem

Artigo Brasil Produção Nacional Revisado por pares

Aline K.A.L. Cipriano, Darcy M.F. Gondim, Ilka M. Vasconcelos, Jorge André Matias Martins, Arlindo A. Moura, Frederico Bruno Mendes Batista Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, José Glauber Moreira Melo, J. E. Cardoso, Ana Luiza Sobral Paiva, José T.A. Oliveira,

Gummosis is an aggressive disease caused by the necrotrophic fungus Lasiodiplodia theobromae (Pat.) Griffon & Maubl that threatens commercial cashew orchads in Brazil. To study the molecular mechanisms involved in the cashew response to L. theobromae, a proteomic analysis of stems from the commercial cashew clone BRS 226 (resistant) was conducted at early times post-artificial infection. In addition, changes in the stem proteome profiles of gummosis resistant and susceptible cashew plants grown under ...

Tópico(s): Plant-Microbe Interactions and Immunity

2014 - Elsevier BV | Journal of Proteomics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Raquel O. Rocha, Janne K. S. Morais, José T.A. Oliveira, Hermógenes David de Oliveira, Daniele O.B. Sousa, Carlos Eduardo A. Souza, Frederico Bruno Mendes Batista Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, José Dijair Antonino, Maria Fátima Grossi‐de‐Sá, Ilka M. Vasconcelos,

Several studies have described the effects of seed exudates against microorganisms, but only few of them have investigated the proteins that have defensive activity particularly against nematode parasites. This study focused on the proteins released in the exudates of soybean seeds and evaluated their nematicidal properties against Meloidogyne incognita. A proteomic approach indicated the existence of 63 exuded proteins, including β-1,3-glucanase, chitinase, lectin, trypsin inhibitor, and lipoxygenase, ...

Tópico(s): Studies on Chitinases and Chitosanases

2015 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

João Paulo Bestete de Oliveira, Márcio V. Ramos, Francisco E.S. Lopes, Igor Cabral Studart, Jefferson Soares de Oliveira, Marina Duarte Pinto Lobo, Ana Cristina de Oliveira Monteiro‐Moreira, Cléverson D.T. Freitas,

Transitory allergies to cow milk proteins in infants or adults have become a public health problem. Although extensively or partially hydrolyzed cow milk protein formulas are available, these products are costly. Therefore, studies into innovative enzymes to digest cow milk proteins are needed. Danaus plexippus gut peptidases were purified and examined with regard to cow milk protein hydrolysis. The peptidases hydrolyzed caseins and whey proteins. However, after heat treatment, there was a significant ...

Tópico(s): Proteins in Food Systems

2018 - Elsevier BV | Food Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Cléverson D.T. Freitas, Hugo B. Leite, João Paulo Bestete de Oliveira, Jackson L. Amaral, Antônio Sílvio do Egito, Sandra Vairo Cavalli, Marina Duarte Pinto Lobo, Ana Cristina de Oliveira Monteiro‐Moreira, Márcio V. Ramos,

Latex fractions from Calotropis procera, Cryptostegia grandiflora, Plumeria rubra, and Himatanthus drasticus were assayed in order to prospect for new plant peptidases with milk-clotting activities, for use as rennet alternatives. Only C. procera and C. grandiflora latex fractions exhibited proteolytic and milk-clotting activities, which were not affected by high concentrations of NaCl and CaCl2. However, pre-incubation of both samples at 75°C for 10min eliminated completely their activities. Both ...

Tópico(s): Enzyme Production and Characterization

2016 - Elsevier BV | Food Research International

Artigo Brasil Produção Nacional Revisado por pares

Flávia Carolina Alonso Buriti, K. M. O. dos Santos, Venícios Gonçalves Sombra, Jeanny S. Maciel, Daniele Maria Alves Teixeira Sá, Hévila Oliveira Salles, Gilcenara Oliveira, Regina C.M. de Paula, Judith P.A. Feitosa, Ana Cristina de Oliveira Monteiro‐Moreira, Renato de Azevedo Moreira, Antônio Sílvio do Egito,

A galactomannan extracted from the endosperm of Caesalpinia pulcherrima seeds was submitted to partial enzymatic hydrolysis to overcome the limitation of use of this polysaccharide as a dietary fibre ingredient, since the intact galactomannan may promote a considerable increase in the viscosity of food products, even when added at low concentrations. The total dietary fibre recovered from the partially hydrolysed galactomannan (PHGM) was 78.27%. The molar mass of PHGM and the absolute viscosity of ...

Tópico(s): Enzyme Production and Characterization

2013 - Elsevier BV | Food Hydrocolloids

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ana Elza Oliveira de Mendonça, Marina de Góes Salvetti, Eulália Maria Chaves Maia, Ana Cristina de Oliveira e Silva, Gilson de Vasconcelos Torres,

OBJECTIVE To identify the main factors of the physical domain modified after kidney transplantation and analyze the influence of those aspects in the perception of Overall quality of life (QOL). METHOD Longitudinal study, conducted with 63 chronic kidney patients, evaluated before and after kidney transplant, using the quality of life scale proposed by the World Health Organization. RESULTS We observed significant improvement in the physical aspects of QOL after kidney transplantation. Significant ...

Tópico(s): Pharmacological Effects and Toxicity Studies

2015 - UNIVERSIDADE DE SÃO PAULO | Revista da Escola de Enfermagem da USP

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Helen Paula Silva da Costa, José T.A. Oliveira, Daniele O.B. Sousa, Janne K. S. Morais, Frederico Bruno Mendes Batista Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, Ricardo Almeida Viégas, Ilka M. Vasconcelos,

Jatropha curcas seed cake is a low-value by-product resulting from biodiesel production. The seed cake is highly toxic, but it has great potential for biotechnology applications as it is a repository of biomolecules that could be important in agriculture, medicine and industry. To explore this potential, a novel trypsin inhibitor called JcTI-I was purified by fractionation of the crude extract with trichloroacetic acid (2.5%, v/v) followed by affinity chromatography (Trypsin-Sepharose 4B) and molecular ...

Tópico(s): Essential Oils and Antimicrobial Activity

2014 - Frontiers Media | Frontiers in Microbiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

P. Rodríguez-Villamil, V. Hoyos-Marulanda, Jorge André Matias Martins, Artur Oliveira, L. H. Aguiar, Frederico Bruno Mendes Batista Moreno, A. L. M. C. S. Velho, Ana Cristina de Oliveira Monteiro‐Moreira, Renato de Azevedo Moreira, Ilka M. Vasconcelos, M. Bertolini, Arlindo A. Moura,

The present study evaluated functional aspects of binder of sperm 1 (BSP1) in the bovine species. In a first experiment, cumulus-oocyte complexes (n = 1274) were incubated with frozen-thawed ejaculated sperm (18 hours) in Fert-TALP medium containing: heparin, 10, 20, or 40 μg/mL BSP1. Heparin followed by gelatin affinity chromatography was used for purification of BSP1 from bovine seminal vesicle fluid. With ejaculated sperm, cleavage rates were similar when Fert-TALP medium was incubated with heparin ( ...

Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

2015 - Elsevier BV | Theriogenology

Artigo Brasil Produção Nacional Revisado por pares

Carlos Eduardo A. Souza, João Paulo Arcelino do Rêgo, Carlos Henrique Lobo, José T.A. Oliveira, Fábio César Sousa Nogueira, Gilberto B. Domont, Mariana Fioramonte, Fábio C. Gozzo, Frederico B. Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, J.R. Figueiredo, Arlindo A. Moura,

The present study is focused on the proteome of reproductive tract fluids from tropically-adapted Santa Ines rams. Seminal plasma, cauda epididymal (CEF) and vesicular gland fluid (VGF) proteins were analyzed by 2-D electrophoresis and mass spectrometry. Seminal plasma maps contained 302 ± 16 spots, within the 4–7 pH range. From these maps, 73 spots were identified, corresponding to 41 proteins. Ram Seminal Vesicle Proteins (RSVP) 14 and 22 kDa and bodhesins 1 and 2 represented the most abundant seminal ...

Tópico(s): Bee Products Chemical Analysis

2012 - Elsevier BV | Journal of Proteomics

Artigo Brasil Produção Nacional Revisado por pares

C.H.A. Oliveira, Aline Maia Silva, L.M. Silva, Maurício Fraga van Tilburg, César Carneiro Linhares Fernandes, Arlindo A. Moura, Frederico Bruno Mendes Batista Moreno, Ana Cristina de Oliveira Monteiro‐Moreira, Renato de Azevedo Moreira, Frederico José Bezerra, Davide Rondina,

Diet can influence both the qualitative and quantitative traits of ruminant meat. This study evaluated the effects of castor de-oiled cake on the meat of mixed-breed male goat kids. After 165 days of diet treatment, no alterations (p > 0.05) were observed in the in vivo performance, anatomic components, dissection and proximate composition of the Longissimus dorsi muscle, as well as in the color and pH of the carcasses. However, diet had an effect (p < 0.05) on energy metabolites, fatty acid profile, ...

Tópico(s): Biodiesel Production and Applications

2015 - Elsevier BV | Meat Science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Henrique P. Oliveira, Rodolpho G.G. Silva, José T.A. Oliveira, Daniele O.B. Sousa, Mirella Leite Pereira, Pedro F.N. Souza, Arlete Aparecida Soares, Valdirene Moreira Gomes, Ana Cristina de Oliveira Monteiro‐Moreira, Frederico Bruno Mendes Batista Moreno, Ilka M. Vasconcelos,

An antifungal class III peroxidase was purified from Marsdenia megalantha latex (named Mo-POX) using DEAE-cellulose and gel filtration chromatography on a Superose 12 HR 10/30 column. Mm-POX has an apparent molecular mass of 67.0 kDa and a pI of 5.2, shares identity with other peroxidases, and follows Michaelis-Menten kinetics. It has a high affinity for guaiacol and hydrogen peroxide. The pH and temperature optima for Mm-POX were 5.0–7.0 and 60 °C, respectively. The catalytic activity of Mm-POX was ...

Tópico(s): Biochemical and biochemical processes

2017 - Elsevier BV | International Journal of Biological Macromolecules

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Patrícia G.C. Landim, Tuana O. Correia, Fredy D.A. Silva, Denise Rocha Nepomuceno, Helen Paula Silva da Costa, H.M. Pereira, Marina Duarte Pinto Lobo, Frederico Bruno Mendes Batista Moreno, J. Brandão-Neto, Suelen Carneiro de Medeiros, Ilka M. Vasconcelos, José T.A. Oliveira, Bruno Lopes de Sousa, Ito L. Barroso-Neto, V. N. Freire, Cristina Paiva da Silveira Carvalho, Ana Cristina de Oliveira Monteiro‐Moreira, Thalles B. Grangeiro,

A cowpea class I chitinase (VuChiI) was expressed in the methylotrophic yeast P. pastoris. The recombinant protein was secreted into the culture medium and purified by affinity chromatography on a chitin matrix. The purified chitinase migrated on SDS-polyacrylamide gel electrophoresis as two closely-related bands with apparent molecular masses of 34 and 37 kDa. The identity of these bands as VuChiI was demonstrated by mass spectrometry analysis of tryptic peptides and N-terminal amino acid sequencing. ...

Tópico(s): Nematode management and characterization studies

2017 - Elsevier BV | Biochimie

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Déborah Ferreira Noronha de Castro Rocha, Luana Rocha da Cunha Rosa, Carla de Almeida Silva, Brunna Rodrigues de Oliveira, Thaynara Lorrane Silva Martins, Regina Maria Bringel Martins, Marcos André de Matos, Megmar Aparecida dos Santos Carneiro, Juliana Pontes Soares, Ana Cristina de Oliveira e Silva, Márcia Maria de Souza, Robert L. Cook, Karlla Antonieta Amorim Caetano, Sheila Araújo Teles,

In recent decades the epidemic of asymptomatic sexually transmitted infections has extended deep into Brazil, including small towns and rural areas. The purpose of this study was to investigate the epidemiology of HIV, syphilis, and hepatitis B (HBV) and hepatitis C viruses (HCV), and to evaluate immunization coverage against hepatitis B in a group of rural workers in Brazil. In 2016, a cross-sectional study was conducted with 937 manual sugarcane cutters of the Midwest and Northeast Regions of Brazil. ...

Tópico(s): HIV/AIDS Research and Interventions

2018 - BioMed Central | BMC Infectious Diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Lucas Pinheiro Dias, José T.A. Oliveira, Lady Clarissa Brito da Rocha-Bezerra, Daniele O.B. Sousa, Helen Paula Silva da Costa, Nadine Monteiro Salgueiro Araújo, Ana Fontenele Urano Carvalho, Pedro MS Tabosa, Ana Cristina de Oliveira Monteiro‐Moreira, Marina Duarte Pinto Lobo, Frederico Bruno Mendes Batista Moreno, B.A.M. Rocha, José Luiz de Souza Lopes, Leila Maria Beltramini, Ilka M. Vasconcelos,

A trypsin inhibitor from Cassia leiandra seeds, named ClTI, was purified, characterized, and its insecticidal activity against Aedes aegypti evaluated. ClTI was purified by DEAE-Cellulose and trypsin-Sepharose 4B chromatography, with a 15.5-fold purification and 2.4% yield. ClTI is composed of a 19,484 Da polypeptide chain as revealed by mass spectrometry, it is not a glycoprotein, its amino acid sequence is similar to other Kunitz-type inhibitors, and it comprises 35% β-sheets, 14% β-turns, and ...

Tópico(s): Insect Pest Control Strategies

2017 - Elsevier BV | Process Biochemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Márcio V. Ramos, Raquel Sombra Basílio de Oliveira, H.M. Pereira, Frederico Bruno Mendes Batista Moreno, Marina Duarte Pinto Lobo, Luciana Magalhães Rebêlo Alencar, J. Brandão-Neto, J. S. de Sousa, Ana Cristina de Oliveira Monteiro‐Moreira, Cléverson D.T. Freitas, Thalles B. Grangeiro,

CpOsm is an antifungal osmotin/thaumatin-like protein purified from the latex of Calotropis procera. The protein is relatively thermostable and retains its antifungal activity over a wide pH range; therefore, it may be useful in the development of new antifungal drugs or transgenic crops with enhanced resistance to phytopathogenic fungi. To gain further insight into the mechanism of action of CpOsm, its three-dimensional structure was determined, and the effects of the protein on Fusarium solani ...

Tópico(s): Natural product bioactivities and synthesis

2015 - Elsevier BV | Phytochemistry

Artigo Brasil Produção Nacional Revisado por pares

Erika Bezerra de Menezes, Rodrigo Vasconcelos de Oliveira, Maurício Fraga van Tilburg, Eleonora Araújo Barbosa, Normandes Vieira Nascimento, A. L. M. C. S. Velho, Frederico Bruno Mendes Batista Moreno, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro‐Moreira, G. M. C. Carvalho, Alexandre Floriani Ramos, Erdoğan Memili, Arlindo A. Moura,

The present study was aimed at evaluating the seminal plasma proteins and sperm parameters of Curraleiro Pé-Duro bulls. Semen was collected from 10 bulls by electroejaculation, and sperm parameters were evaluated in fresh and frozen-thawed semen. Seminal plasma proteins were analyzed by 2-D SDS-PAGE and mass spectrophotometry. Tools in computational biology were used to generate bioinformatic knowledge and evaluate gene ontology, protein–protein interactions, phylogenetic trees and multiple sequence ...

Tópico(s): Iron Metabolism and Disorders

2017 - Elsevier BV | Animal Reproduction Science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

João X. S. Neto, Mirella Leite Pereira, José T.A. Oliveira, Lady Clarissa Brito da Rocha-Bezerra, Tiago Deiveson Pereira Lopes, Helen Paula Silva da Costa, Daniele O.B. Sousa, B.A.M. Rocha, Thalles B. Grangeiro, José Ednésio da Cruz Freire, Ana Cristina de Oliveira Monteiro‐Moreira, Marina Duarte Pinto Lobo, Raimunda Sâmia Nogueira Brilhante, Ilka M. Vasconcelos,

Candida species are opportunistic pathogens that infect immunocompromised and/or immunosuppressed patients, particularly in hospital facilities, that besides representing a significant threat to health increase the risk of mortality. Apart from echinocandins and triazoles, which are well tolerated, most of the antifungal drugs used for candidiasis treatment can cause side effects and lead to the development of resistant strains. A promising alternative to the conventional treatments is the use of ...

Tópico(s): Agricultural pest management studies

2017 - Frontiers Media | Frontiers in Microbiology