Ana Paula Matos, Ana Cláudia Cardoso Machado,
A asma brônquica é uma doença complexa e interfere com a qualidade de vida desses doentes. Pretendemos, com a presente investigação, estudar a relação das variáveis sócio-demográficas (género, idade e grau de instrução), clínicas (gravidade da doença, duração e tipo clínico) e psicológicas (cognições, emoções e comportamentos) com a qualidade de vida do doente asmático. Cinqüenta doentes asmáticos do Departamento de Pneumologia e Imunoalergologia dos Hospitais da Universidade de Coimbra preencheram ...
Tópico(s): Health, psychology, and well-being
2007 - UNIVERSIDADE DE BRASÍLIA | Psicologia Teoria e Pesquisa
Raquel Guiomar, Ana João Santos, Aryse Martins Melo, Inês Costa, Rita Matos, Ana Paula Rodrigues, Irina Kislaya, Anabela Santos Silva, Carla Roque, Carla Nunes, J. M. Aguiar, Fátima Graça, António Silva Graça, Ausenda Machado,
Vaccination is considered the most important measure to control the COVID-19 pandemic. Extensive follow-up studies with distinct vaccines and populations are able to promote robust and reliable data to better understand the effectiveness of this pharmacologic strategy. In this sense, we present data regarding binding and neutralizing (achieved by surrogate ELISA assay) antibodies throughout time, from vaccinated and previously infected (PI) health care workers (HCW) in Portugal. We analyzed serum samples ...
Tópico(s): SARS-CoV-2 detection and testing
2022 - Multidisciplinary Digital Publishing Institute | Vaccines
Produção Nacional
Revisado por pares
Jéssica Bassetto Carra, Ricardo Luís Nascimento de Matos, Ana Paula Novelli, Renê Oliveira do Couto, Fábio Yamashita, Marcos Ribeiro, Eduardo C. Meurer, Waldiceu A. Verri, Rúbia Casagrande, Sandra R. Georgetti, Nilton Syogo Arakawa, Marcela M. Baracat,
Novel microcapsules containing grape peel by-product extract were obtained. In this pursuit, complex coacervation of casein/pectin bioconjugate and spray-drying were combined. We have investigated the role of the dispersion feed rate (FR), drying air inlet temperature (IT) and drying air flow rate (AR) in the drying yield, microencapsulation efficiency, total polyphenols and anthocyanins contents, antioxidant activity, and morphology of the products. Also, the first-order degradation kinetics of the ...
Tópico(s): Bee Products Chemical Analysis
2021 - Elsevier BV | Food Chemistry
Produção Nacional
Revisado por pares
Cristiana C. Garcia, Luciana P. Tavares, Ana Carolina Fialho Dias, Fernanda S. G. Kehdy, Lucia Elena Alvarado-Arnez, Celso Martins Queiroz‐Junior, Izabela Galvão, Bráulio Henrique Freire Lima, Aline da Rocha Matos, Ana Paula Gonçalves, Frederico Marianetti Soriani, Milton Ozório Moraes, João T. Marques, Marilda Mendonça Siqueira, Alexandre V. Machado, Lirlândia P. Sousa, Remo Castro Russo, Mauro Martins Teixeira,
: Influenza A virus (IAV) infection causes severe pulmonary disease characterized by intense leukocyte infiltration. Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes, involved in cell growth, survival and migration. Class IB PI3K or PI3Kγ, mainly expressed by leukocytes, are involved in cell migration during inflammation. Here, we investigated the contribution of PI3Kγ for the inflammatory and antiviral responses to IAV. PI3Kγ knock out (KO) mice were highly susceptible to lethality following ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2018 - Frontiers Media | Frontiers in Immunology
Carla Viegas, L. Santos, Anjos L. Macedo, António Matos, Ana Paula Silva, Pedro Leão Neves, An Staes, Kris Gevaert, Rute Morais, Cees Vermeer, Leon J. Schurgers, Dina C. Simes,
Inhibition of mineral crystal formation is a crucial step in ectopic calcification. Serum calciprotein particles (CPPs) have been linked to chronic kidney disease (CKD) calcification propensity, but additional knowledge is required to understand their function, assemblage, and composition. The role of other circulating nanostructures, such as extracellular vesicles (EVs) in vascular calcification is currently unknown. Here, we investigated the association of GRP (Gla-rich protein) with circulating CPP ...
Tópico(s): Heterotopic Ossification and Related Conditions
2018 - Lippincott Williams & Wilkins | Arteriosclerosis Thrombosis and Vascular Biology
Sandra Martins, Fernanda Simões, Diogo Mendonça, José Matos, Ana Paula Silva, V. Carnide,
Hazelnut (Corylus avellana L.), a member of the family Betulaceae and the order Fagales, is native to Europe, Turkey, and the Caucasus. It has been cultivated for more than 5000 years. The majority of cultivars were selected from local wild populations over the past few centuries. Hazelnut is native to northern Portugal, with local production from landrace clonal selections. In recent years, hazelnut production has declined, and landraces are in danger of being lost. In this study, we used 16 microsatellite ...
Tópico(s): Horticultural and Viticultural Research
2015 - Springer Science+Business Media | Plant Molecular Biology Reporter
Produção Nacional
Revisado por pares
Gilda Maria Amarante Matos, Marlécio Maknamara, Elaine Cristine Amarante Matos, Ana Paula Nascimento Prata,
Os recursos didáticos são considerados elementos importantes no trabalho dos conteúdos de Botânica. Este trabalho objetivou testar e avaliar os diferentes recursos didáticos e atividades práticas elaboradas pelos licenciandos do Curso de Ciências Biológicas da Universidade Federal de Sergipe que enfatizaram o Ensino de Botânica em suas monografias. Os recursos foram aplicados em uma escola pública aracajuana e avaliados por meio de questionário e ficha própria. O caráter diferente e criativo destas ...
Tópico(s): Education and Digital Technologies
2015 - INSTITUTO FEDERAL DO RIO GRANDE DO NORTE | Holos
Hugo Matos, Ana Paula Nassif Tondato da Trindade, Maria José Noruegas,
The objective of this study was to obtain a normal value for liver shear wave velocities (SWVs) in healthy paediatric patients and to investigate variations concerning age, sex, and different approaches, depths, and lobes of measurements.A total of 150 healthy children (2 months-17 years) were examined with acoustic radiation force impulse (ARFI) technology by an experienced paediatric radiologist, after receiving an informed consent. Measurements obtained were divided according to group age (n = 50, ...
Tópico(s): Ultrasound Imaging and Elastography
2014 - Lippincott Williams & Wilkins | Journal of Pediatric Gastroenterology and Nutrition
Sandra Martins, Fernanda Simões, José Matos, Ana Paula Silva, V. Carnide,
The genus Corylus, a member of the birch family Betulaceae, includes several species that are widely distributed throughout temperate regions of the Northern Hemisphere. This study assesses the genetic diversity in 26 international cultivars and 32 accessions of Corylus avellana L. from Portugal: 13 wild genotypes and 19 landraces. The genetic relationships among the 58 hazelnuts (Corylus avellana L.) were analyzed using inter simple sequence repeat (ISSR) and amplified fragment length polymorphism ( ...
Tópico(s): Natural product bioactivities and synthesis
2013 - Springer Science+Business Media | Plant Systematics and Evolution
Ana Sofia Fonseca, Maria Isabel Nunes, M.A.A. Matos, Ana Paula Gomes,
Tópico(s): Municipal Solid Waste Management
2013 - Springer Science+Business Media | The International Journal of Life Cycle Assessment
Produção Nacional
Revisado por pares
Roberta Nogueira Chaves, Anelise Maria Costa Vasconcelos Alves, Laritza Ferreira de Lima, M.H.T. Matos, Ana Paula Ribeiro Rodrigues, J.R. Figueiredo,
Summary Nerve growth factor (NGF) is a prototype member of the neurotrophins family and has important functions in the maintenance of viability and proliferation of neuronal and non-neuronal cells, such as certain ovarian cells. The present review highlights the role of NGF and its receptors on ovarian follicle development. NGF initiates its multiple actions through binding to two classes of receptors: the high affinity receptor tyrosine kinase A (TrkA) and the low-affinity receptor p75. Different ...
Tópico(s): Tendon Structure and Treatment
2012 - Cambridge University Press | Zygote
Sandra Martins, Fernanda Simões, Diogo Mendonça, José Matos, Ana Paula Silva, V. Carnide,
The genus Corylus, a member of the birch family Betulaceae, includes several species that are widely distributed throughout temperate regions of the Northern Hemisphere. The development of microsatellites or simple sequence repeats (SSRs) for non-coding regions of the chloroplast genome and their higher sequence variation compared with coding regions has provided a higher resolution tool for the study of cultivars and closely related taxa. Chloroplast polymorphisms provide a marker system to evaluate ...
Tópico(s): Plant Ecology and Taxonomy Studies
2012 - Springer Science+Business Media | Genetic Resources and Crop Evolution
Produção Nacional
Revisado por pares
Ilane Magalhães Silva, Ana María Fontenelle Catrib, Vânia Cordeiro de Matos, Ana Paula Soares Gondim,
O estudo visa analisar o conhecimento dos estudantes de escolas públicas e privadas do município de Fortaleza (CE) sobre o uso de medicamentos e suas implicações para a saúde. Trata-se de um estudo descritivo, com 722 adolescentes matriculados em dez escolas do município de Fortaleza. Levantou-se, por meio de um questionário, aspectos relativos ao consumo, indicação e orientação de medicamentos e a influência da mídia. Relataram uso de medicamentos, nos últimos sessenta dias, 72,0% dos participantes, ...
Tópico(s): Healthcare Regulation
2011 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Fabiana Bombonato Mingossi, Juliana L. Matos, Ana Paula Rizzato, Ane Hackbart Medeiros, Maria Cristina Falco, Márcio C. Silva-Filho, Daniel S. Moura,
Tópico(s): Plant Stress Responses and Tolerance
2010 - Springer Science+Business Media | Plant Molecular Biology
Susana Relvas, Henrique A. Matos, Ana Paula Barbosa‐Póvoa, João Fialho,
Real world scenarios on the planning and scheduling of the complex oil supply chain represent challenging problems. However, there is a growing need to establish decision support tools capable of dealing with competition within this industry so as to replace simple procedures, such as spreadsheets, with more efficient tools. This work studies a medium term scheduling problem of a pipeline and associated end-of-pipe tank farm. The mixed integer linear problem (MILP) formulation proposed by Relvas ...
Tópico(s): Reservoir Engineering and Simulation Methods
2007 - American Chemical Society | Industrial & Engineering Chemistry Research
Produção Nacional
Revisado por pares
Patrícia Matos, Ana Paula C. Ferreira, Laura Sterian Ward,
Tópico(s): Thyroid Disorders and Treatments
2006 - Springer Science+Business Media | Endocrine Pathology
Produção Nacional
Revisado por pares
João Gustavo Gongora Ferraz, André Luiz Mylonas Martins, João Francisco de Souza, Aline da Rocha Matos, Ana Paula Canto, Alfredo Mylona Martins,
Mulher de 63 anos com história pregressa de câncer de útero e queixa de fadiga e dispnéia aos pequenos esforços. Ao exame, apresentava-se hipertensa e com estertores de bases pulmonares. O ecocardiograma transtorácico mostrou massa de pouca mobilidade em ventrículo direito. A paciente foi levada para cirurgia, ocasião em que se encontrou uma massa envolvendo a parede anterior da artéria pulmonar, valva tricúspide, átrio direito e parede posterior do ventrículo direito. A artéria pulmonar e o ventrículo ...
Tópico(s): Cardiac Structural Anomalies and Repair
2006 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Susana Relvas, Henrique A. Matos, Ana Paula Barbosa‐Póvoa, João Fialho, António S. Pinheiro,
Within the oil supply chain, although refinery operations are extensively studied, distribution center operations are not being explored to their full potential. In this paper, these types of operations are studied. A mixed-integer linear programming (MILP) approach is used to model the problem of oil derivatives pipeline transportation scheduling and supply management. The objective of the model is to attain a high level of operation, satisfying clients and accounting for distribution center restrictions ...
Tópico(s): Scheduling and Optimization Algorithms
2006 - American Chemical Society | Industrial & Engineering Chemistry Research
Produção Nacional
Revisado por pares
Patrícia Matos, Ana Paula C. Ferreira, F De Oliveira Facuri, Lígia Vera Montali da Assumpção, Konradin Metze, Laura Sterian Ward,
Aims : To investigate the usefulness of immunohistochemical expression and immunolocalization of a panel of thyroid malignancy markers including HBME‐1, cytokeratin (CK) 19 and galectin‐3. Methods and results : We evaluated 170 thyroid lesions including 148 neoplastic lesions [84 papillary carcinomas (PC), 38 follicular carcinomas (FC), 18 follicular adenomas, one hyalinizing trabecular tumour, five medullary carcinomas, two anaplastic carcinomas] and 22 non‐neoplastic lesions (12 adenomatous nodules and ...
Tópico(s): Skin and Cellular Biology Research
2005 - Wiley | Histopathology
Produção Nacional
Revisado por pares
Evelyn Rabelo Andrade, Christiani A. Amorim, M.H.T. Matos, Ana Paula Ribeiro Rodrigues, J.R.V. Silva, Margot Alves Nunes Dode, J.R. Figueiredo,
This efficiency of saline and coconut water solutions in the preservation of sheep preantral follicles in situ at different temperatures and incubation periods was investigated. At the slaughterhouse, each pair of ovaries was divided into 19 fragments. One ovarian fragment was immediately fixed for histology (control time zero). The other 18 ovarian fragments were randomly distributed in tubes containing 2 ml of saline or coconut water solutions at 4, 20 or 39 °C and then stored for 4, 12 or 24 h. ...
Tópico(s): Ovarian function and disorders
2002 - Elsevier BV | Small Ruminant Research
Pedro M. Castro, Henrique A. Matos, Ana Paula Barbosa‐Póvoa,
This paper addresses the optimal schedule of a resource constrained four-batch digester system of an industrial acid sulphite pulp mill. This involves the development of two different models, one to model the scheduling operational problem and the other the batch digester operation—process model. The first model uses a discrete-time Resource Task Network (RTN) based representation leading to a Mixed Integer Linear Program (MILP) formulation. In this, the main operational limitation, steam availability, ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2002 - Elsevier BV | Computers & Chemical Engineering
Produção Nacional
Revisado por pares
R.C. Afonso, Raíssa Mara Kao Yien, Luciana Betzler de Oliveira de Siqueira, Naomi Kato Simas, Ana Paula dos Santos Matos, Eduardo Ricci‐Júnior,
Although there are available treatments for cutaneous leishmaniasis (CL), the drugs used are far from ideal, toxic, and costly, in addition to the challenge faced by the development of resistance. Plants have been used as a source of natural compounds with antileishmanial action. However, few have reached the market and become phytomedicines with registration in regulatory agencies. Difficulties related to the extraction, purification, chemical identification, efficacy, safety, and production in ...
Tópico(s): Insect Pest Control Strategies
2023 - Elsevier BV | Experimental Parasitology
Devon LoParo, António Castro Fonseca, Ana Paula Matos, W. Edward Craighead,
Tópico(s): Autism Spectrum Disorder Research
2023 - Springer Nature | Research on Child and Adolescent Psychopathology
Produção Nacional
Revisado por pares
Ana Paula Matos Porto, Igor C. Borges, Lewis Buss, Anna Machado, Bil Randerson Bassetti, Brunno César Batista Cocentino, Camila S Bicalho, Claudia M D M Carrilho, Cristhieni Rodrigues, Eudes Alves Simões Neto, Evelyne Santana Girão, Filipe Teixeira Piastrelli, Giovanna T. Sapienza, Glaucia Fernanda Varkulja, Karin Kolbe, Luciana Neves Passos, Patrícia Esteves, Pollyana Gitirana, Regia D F Feijó, Rosane Luiza Coutinho, Thaís Guimarães, Tiago Luiz Lagedo Ferraz, Anna S. Levin, Sílvia Figueiredo Costa,
The coronavirus disease 2019 (COVID-19) pandemic has caused a global health crisis and may have affected healthcare-associated infection (HAI) prevention strategies. We evaluated the impact of the COVID-19 pandemic on HAI incidence in Brazilian intensive care units (ICUs).In this ecological study, we compared adult patients admitted to the ICU from April through June 2020 (pandemic period) with the same period in 2019 (prepandemic period) in 21 Brazilian hospitals. We used the Wilcoxon signed rank-sum ...
Tópico(s): Infection Control in Healthcare
2022 - Cambridge University Press | Infection Control and Hospital Epidemiology
Ines Pauwels, Ann Versporten, Nico Drapier, Erika Vlieghe, Herman Goossens, Andi Koraqi, Iris Hoxha, Silva Tafaj, Wanda Cornistein, Rodolfo Quirós, Martín Hojman, Lilit Ghazaryan, Kylie Horne, Kelly A. Cairns, Fiona Doukas, Thomas Gottlieb, Erica Sermijn, Katia Verhamme, Christiane Brands, Bruno Van Herendael, Lorenzo Filippin, Wouter Vandewal, Déborah Konopnicki, Evelyne Maillart, Liliana Teixeira Lopes, Pauline Papin, Ilse Smits, Hilde Jansens, Sofie Bartholomeus, Anne‐Marie Van den Abeele, Sophia Steyaert, Anne Piette, Franky Buyle, Reinoud Cartuyvels, Stijn Jonckheere, Ingrid Wybo, Lorenz Vanneste, Delphine Mathieu, Éric Firre, Veerle Westelinck, Philippe Gadisseux, Thierry Dugernier, Kristof Bafort, Viviane Gonissen, Vanessa Vanderper, Patrick Gabriels, Frank Weekers, Philippe Michel, Ann Van Liedekerke, Michiel Costers, Boudewijn Catry, Amela Dedeić-Ljubović, Ana Cristina Gales, Ana Paula Matos Porto, Sílvia Figueiredo Costa, Emma Keuleyan, Apollinaire Beidi, Youssouph Cissohko, Habsatou Blakwe, Ngassa Batchaya Basile, Greg J. German, Sarah Lutes, Jennifer Boswell, Dominik Mertz, Tuyen Nguyen, Timothy MacLaggan, Daniel Landry, Anita Ang, Daniel J. G. Thirion, Charles Frenette, Yannick Émond, Jacqueline Roberts, Sandra Chang, Justin Kosar, Louis Valiquette, Ginette Dutrisac, Kevin Afra, Allison McGeer, Marie Carrier, Jennifer Grant, Jaime Labarca, Camila Carvajal, HongYi Lin, Qiang Wang, Jing Yang, Wenjie Yang, Jorge Alberto Cortés, Juan Villalobos-Vindas, Carlos Ramírez-Valverde, Jasminka Horvatić, Irina Pristaš, Niki I. Paphitou, Maija‐Liisa Rummukainen, Antoine Froissart, Philippe Vanhems, Karaman Pagava, Irma Korinteli, Tobias Brandt, Johannes Gaertner, Anthony Enimil, Emmanuel Roilides, Edit Hajdú, Sharmila Sengupta, Sanjeev Singh, Priyanka Patil, Aruna Poojary, Jafar Soltani, Gholamreza Pouladfar, Zahra Jafarpour, Cyrus Alinia, Hadi Ameen, David Fitzgerald, Mical Paul, Yasmin Maor, Jacob Strahilevitz, Michal Chowers, Elizabeth Temkin, Luca Arnoldo, Noriomi Ishibashi, Yoshiaki Gu, Feras Darwish Elhajji, Aizhan Karabukayeva, Denis Raka, Baktygul Kambaralieva, Lelde Zarakauska, Peter Zarb, Blanca Estela Hernandez Chena, Esteban González-Díaz, Juan Carlos Corona Meléndez, Darwin Stalin Torres-Erazo, Suria Elizabeth Loza-Jalil, Julio Molina, Jose Antonio Candelas, Gordana Mijović, Nataša Duborija-Kovačević, Eefje Jong, Jan Kluytmans, Erika van Elzakker, Valentijn A. Schweitzer, Nicola Davies, Kenneth Iregbu, Philip Nwajiobi-Princewill, Ifeyinwa Nwafia, Temitayo Fasuyi, Aaron O. Aboderin, Charles John Elikwu, A Fadeyi, Olafoyekemi Ola-Bello, O.O. Oduyebo, Akin Nelson Adedosu, Agantem Emmanuel Ekuma, Erjona Shaqiri, Zikria Saleem, Mari Rose De Los Reyes, Luís Tavares, Nam Joong Kim, Svetlana Rachina, Alwaleed R Alharthi, Mushira Enani, Osama Ahmed Faried, Mohamed Mirghani, Biljana Carević, Lili Radulovic, Gorana Dragovac, Sock Hoon Tan, Jantjie Taljaard, Vindana Chibabhai, Jennifer Joiner, Juan José Castón, María Núñez‐Núñez, Francisco Javier Martínez‐Marcos, Guillermo Ojeda, María Menéndez, Pilar Retamar, Juan E. Corzo, Pinyo Rattanaumpawan, Mounérou Salou, Basma Mnif, Ahsen Öncül, Peter Ahabwe Babigumira, James Olweny, Emily Gard Marshall, Ann McCorry, Mamoon A. Aldeyab, Priya Khanna, Cairine Gormley, Sara Maloney, Mandelin Cooper, Laura Blackburn, Mallory Gessner-Wharton, Lam Vu, Nickie Greer, Gerard Gawrys, Lisha Kronmann, Edgar Rios, Melissa M. Hudson, David A Lindholm,
The WHO Access, Watch and Reserve (AWaRe) classification has been developed to support countries and hospitals in promoting rational use of antibiotics while improving access to these essential medicines. We aimed to describe patterns of worldwide antibiotic use according to the AWaRe classification in the adult inpatient population.The Global Point Prevalence Survey on Antimicrobial Consumption and Resistance (Global-PPS) collects hospital antibiotic use data using a standardized PPS methodology. ...
Tópico(s): Patient Satisfaction in Healthcare
2021 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Sílvia Figueiredo Costa, Pedro Giavina‐Bianchi, Lewis Buss, Carlos Henrique Mesquita Peres, Mayra Matias Rafael, Lanuse Garcia Neves dos Santos, Anderson Aparecido Bedin, Maria Cristina Peres Braido Francisco, Fatima Mitie Satakie, Maria Aparecida Jesus Menezes, Lígia Maria Dal Secco, Deyse Mayara Rodrigues Caron, Allan Brum de Oliveira, Matheus Finardi Lima de Faria, Angelica Sauiuri de Aurélio Penteado, Izabel Oliva Marcilio de Souza, Grazielly de Fátima Pereira, Rafael H. M. Pereira, Ana Paula Matos Porto, Evelyn Patrícia Sánchez Espinoza, Maria Cássia Mendes-Corrêa, Carolina dos Santos Lázari, Jorge Kalil, Maria Beatriz de Moliterno Perondi, Eloísa Bonfá, Antonio Jose Perreira, Éster Cerdeira Sabino, Alberto José da Silva Duarte, Aluísio Augusto Cotrim Segurado, Vera Aparecida dos Santos, Anna S. Levin,
We evaluated the seroprevalence of SARS-CoV-2 and risk factors among 4987 oligo/asymptomatic healthcare workers; seroprevalence was 14% and factors associated with SARS-CoV-2 infection were lower educational level (aOR, 1.93; 95% CI, 1.03-3.60), using public transport to work (aOR, 1.65; 95% CI, 1.07-2.62), and working in cleaning or security (aOR, 2.05; 95% CI, 1.04-4.03).
Tópico(s): COVID-19 and Mental Health
2020 - Oxford University Press | Clinical Infectious Diseases
Produção Nacional
Revisado por pares
Ana Paula Matos Porto, Herman Goossens, Ann Versporten, Sílvia Figueiredo Costa,
Background The inappropriate use of antimicrobials and increased rates of antimicrobial resistance is a challenge all over the world. Although antibiotic stewardship is recommended by the Brazilian government, data regarding antibiotic use in Brazilian hospitals are scarce. The aim of this study was to conduct a point prevalence survey of antimicrobial use in 18 Brazilian hospitals. Methods Eighteen Brazilian hospitals conducted the Global Point Prevalence Survey of Antimicrobial Consumption and ...
Tópico(s): Antibiotic Resistance in Bacteria
2019 - Elsevier BV | Journal of Hospital Infection
Thorhildur Halldorsdottir, Charlotte Piechaczek, Ana Paula Matos, Darina Czamara, Verena Pehl, Petra Wagenbuechler, Lisa Feldmann, Peggy Quickenstedt-Reinhardt, Antje‐Kathrin Allgaier, Franz Joseph Freisleder, Ellen Greimel, Tuomas Kvist, Jari Lahti, Katri Räikkönen, Monika Rex‐Haffner, Eiríkur Örn Arnarson, W. Edward Craighead, Gerd Schulte‐Körne, Elisabeth B. Binder,
Objective: Identifying risk factors for major depression and depressive symptoms in youths could have important implications for prevention efforts. This study examined the association of polygenic risk scores (PRSs) for a broad depression phenotype derived from a large-scale genome-wide association study (GWAS) in adults, and its interaction with childhood abuse, with clinically relevant depression outcomes in clinical and epidemiological youth cohorts. Methods: The clinical cohort comprised 279 ...
Tópico(s): Cognitive Abilities and Testing
2019 - American Psychiatric Association | American Journal of Psychiatry
Produção Nacional
Revisado por pares
Ricardo Silveira Yamaguchi, Danilo Teixeira Noritomi, Natália Viu Degaspare, Gabriela Ortega Cisternas Muñoz, Ana Paula Matos Porto, Sílvia Figueiredo Costa, Otávio T. Ranzani,
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2017 - Springer Science+Business Media | Intensive Care Medicine
Thorhildur Halldorsdottir, Ana Paula Matos, Yvonne Awaloff, Eiríkur Örn Arnarson, W. Edward Craighead, Elisabeth B. Binder,
Maladaptive emotion regulation strategies, such as rumination and catastrophizing, are transdiagnostic risk factors for psychopathology. FK506-binding protein 51 (FKBP5) has been found to moderate the relationship between stressful life events and various psychiatric disorders. Given the cross-disorder moderation effect of FKBP5 at the diagnostic level, the aim of the current study was to examine whether the relationship between exposure to childhood trauma and transdiagnostic maladaptive emotion ...
Tópico(s): Early Childhood Education and Development
2017 - Elsevier BV | Psychoneuroendocrinology