Giles Smith, Andrew Robson, Amanda Andrews, Christina Hardyment, John McNamara, Amy Lame, Squart Meal's, Gabriel Rozenberg and Gary Duncan, David Townsend, Robert Cole, Portia Colwell, Bel Mooney, Andrew Pierce, Phill Jupitus, Alexandra Frean, Alan M. Pardoe, Alex Partridge, Jane MacQuitty, Simon Barnes, Steve Gailor, Peter Lansley, Alex Stewart, Hannah Devlin, Rachel Tims, Richard Hobson, John Mulvey, David Powell Athletcs Correspondent, M. N. Wright, Tony Turnbull, Dr Toby Murcott, Philip Howard, Peter Mueller, Simon Cambers, Carol Midgley, Christine Seib, David Chater, Kate Wighton, Michael Binyon, James Ducker, Lucy Porter, Dominic Wells, Clive Davis, Kate Reardon, Luke Magee, Anne Gatti, Bob Stanley, Graham Stewart, Elizabeth Lumb, Ginny Dougary, Martin Aston, Wendy Ide, John Bungey, Mona Clark, Lucy Bannerman, Professor Eric Thomas, Andrew Norfolk, Giles Coren, Peter Wilson, Rosie Millard, Martin Jarvis, John Burnside, Dr Copperfield, Pat Gibson, Nancy Durrant, Jane MacArtney, Richard Owen and Richard Beeston, Nigel Kenall, Aidan Clegg, Jack Malvern, Tom Bawden, Steve Bird, Midge Gilles, Debra Craine, Andrew Murray, Allan Simmons, Dr Jane Collins, Daniel Finkelstein, Angela Jameson Industrial Correspondent, David R. Robinson, Peter Ackroyd, Jo Morris, Alan Hamilton, Mark Bradshaw, Elaine Feinstein, Angus McBean, Nick Wyke, Rhys Blakely, Alex Pozniak, Richard Lloyd Parry, David Hands, Charles Bremner, Jonathan Richards, Ian MacKinnon, Ben MacHell, Stefanie Marsh, Lucy Sweeney, William Shawcross, Tim Teeman, Darren Oldridge, Hugo Rifkind, Derwent May, Matthew Pinsent, Anthony F. Bagnall, Aggie MacKenzie, Russell Kempson, Paula Hawkins, Ashley Kahn, Christopher Hilton, Ernie Todd, Wendy Hoffman, Nigel Williamson, Adam Fresco and Alexandra Blair, Ed Potton, Gary Duncan Economics Editor, Oliver Kay, Amber Cowan, Stephen Anderton, Mark Atherton, Angus Donald, Dominic Kennedy, Chiade O'Shea and Hannah Devlin, Michael Theodoulou, Ed Smith, Lisa Armstrong, Mavis Cheek, Antonia Senior Personal Finance Editor, Christopher Martin-Jenkins, Sally Baker, Pete Paphides, Simon de Bruxelles, Rob Wright, Geoffrey Dean, Christina Koning, Bernard Lagan, Nick Barlay, Brian P. Moss, Raymond Keene, Gerald Morgan, Suzi Godson, Kate Saunders, Matthew Pryor, Felipe Fernández-Armesto, Louise Cardani, John Russell Taylor, Rebecca O'Connor, Gordon Ramsay, Benji Wilson, Robert Beavis, Joyce Carol Oates, Peta Bee, Rick Jones, Neville Scott, Zoë Strimpel, Patrick Hosking, Ross Leckie, Marcel Berlins, Roger Boyes, Peter Dixon, Nick Hasell, A. Johnson, Lucy Powell, Graham Searjeant Personal Investor, Margaret Reynolds, David Hands Rugby Correspondent, Tom Dart, Julian Muscat, Paul Simons, Nicholas Clee, Ann Brady, Nigel Kendall, John Goodbody, Brian Tossell, Chimamanda Ngozi Adichie, John Walsh, Giles Whittell, Robert Crampton, Jane Shilling, Ian James, Alex O'Connell, Ian Johns, Dominic Maxwell, Barry Buckley, Roderick Strange, Matthew Parris, Thomas Catan, Mike Rosewell, Mark Hodkinson, Amanda Craig, Alan Franks, Rebecca Ley, Caitlin Moran, Sheila Keating, Celia Dodd, Neil Fisher, Iain Finlayson, Keith Richardson, Fred Craven, Pauline McLynn, John Naish, Clem Stevens, Martin Waller, Alexandra Frean and Alexandra Blair, Steve Bird and John Carr, Chris Ayres, Mark Henderson, Tom Bawden and Sarah Butler, Carl Mortished International Business Editor, Mark Baldwin, Sarah Butler, Anna Shepard, Benedict Nightingale, Oliver Kamm, Louise Cohen, Dr Thomas Stuttaford, Jill Crawshaw, Stephen Dalton, Robin Hutson, Nicola Woolcock, Andy Connell, Bill Edgar, Alyson Rudd, Tom Chesshyre, James Christopher, Richard Morrison, Simon Crompton, Mark Harrison, Olav Bjortomt, Cath Urquhart Travel Editor, Ken Thomas, Will Hide, Jan Raath, David Robertson, Christopher Irvine, Dominic Kennedy and Hannah Devlin, Bryan G. Whitman,
... campery, Pedro Almodóar's films are in many Leao a müller Life Lead a müller Life Boots ...
2006 - Gale Group | TDA
Produção Nacional
Revisado por pares
Elenilze F. B. Ferreira, Luciane B. Silva, Glauber Vilhena da Costa, Josivan S. Costa, Mayara Amoras Teles Fujishima, Rozires P. Leão, André L. S. Ferreira, Leonardo Bruno Federico, Carlos Henrique Tomich de Paula da Silva, Joaquín M. Campos Rosa, Williams Jorge da Cruz Macêdo, Cleydson B. R. Santos,
Leukemias are neoplasms that affect hematopoietic cells, which are developed by genetic alterations (mutations) that lead to the loss of proliferation control mechanisms (maturation and/or cell death). The α4β1 integrin receptor is a therapeutic target for inflammation, autoimmune diseases and lymphoid tumors. This study was carried out to search through the antagonists-based virtual screening for α4β1 receptor. Initially, seventeen (17) structures were selected (based on the inhibitory activity values, ...
Tópico(s): Click Chemistry and Applications
2019 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Anderson H.F.F. Leão, André M. Medeiros, Gênedy Apolinário, Alícia Cabral, Alessandra Mussi Ribeiro, Flávio Freitas Barbosa, Regina H. Silva,
The plus-maze discriminative avoidance task (PMDAT) has been used to investigate interactions between aversive memory and an anxiety-like response in rodents. Suitable performance in this task depends on the activity of the basolateral amygdala, similar to other aversive-based memory tasks. However, the role of spatial cues and hippocampal-dependent learning in the performance of PMDAT remains unknown. Here, we investigated the role of proximal and distal cues in the retrieval of this task. Animals ...
Tópico(s): Neuroscience and Neuropharmacology Research
2016 - Elsevier BV | Behavioural Brain Research
Produção Nacional
Revisado por pares
Valéria S. Fernandes, José R. Santos, Anderson H.F.F. Leão, André M. Medeiros, Thieza G. Melo, Geison Souza Izídio, Alícia Cabral, Rosana A. Ribeiro, Vanessa C. Abı́lio, Alessandra Mussi Ribeiro, Regina H. Silva,
Animal models are widely used to study alterations caused by Parkinson's disease (PD). However, in general, pharmacological models do not express the progressive nature of the disease, being characterized by immediate severe motor impairment after a single dose of the drug. Reserpine administration in rodents has been suggested as a pharmacological model of PD based on the effects of this monoamine-depleting agent on motor activity. Here, we describe that repeated administration with a low dose (0. ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2012 - Elsevier BV | Behavioural Brain Research
Produção Nacional
Revisado por pares
Dinah Sá Rezende Neta, Anne Karolinne e Silva Alves, Gustavo de Moura Leão, André Alves de Araújo,
O estudo objetivou investigar o perfil das ocorrências de politrauma em condutores motociclísticos atendidos pelo Serviço de Atendimento Móvel de Urgência de Teresina-PI. Realizou-se um estudo quantitativo e documental, mediante informações colhidas das fichas de atendimento desse serviço no ano de 2009. A coleta dos dados ocorreu nos meses de fevereiro e março do ano de 2010. As motocicletas envolveram-se em 84% dos acidentes, sendo os homens de 21 a 30 anos os mais acometidos. O final de semana ...
Tópico(s): Automotive and Human Injury Biomechanics
2012 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Edênio Detmann, Mário Fonseca Paulino, Luciano da Silva Cabral, Sebastião de Campos Valadares Filho, Paulo Roberto Cecon, Joanis Tilemahos Zervoudakis, Rogério de Paula Lana, Maria Ignêz Leão, André José Nunes Melo,
Objetivou-se simular e validar a degradação ruminal dos carboidratos e o fluxo nitrogenado microbiano, estimados a partir de parâmetros da cinética de degradação ruminal de amostras de extrusa esofágica e de suplementos obtidos pela técnica in vitro de produção de gases. As estimativas in vivo foram obtidas em experimento de campo, no qual foram utilizados cinco novilhos mestiços Holandês x Zebu com idade e peso médios iniciais de 24 meses e 304 kg, manejados em cinco piquetes de B. decumbens (0, ...
Tópico(s): Effects of Environmental Stressors on Livestock
2005 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
Gabriela Silva Ribeiro Gonçalves, Pablo Vieira Cerqueira, Daniel Paiva Silva, Letícia Braga Gomes, Camila Ferreira Leão, André Felipe Alves de Andrade, Marcos Pérsio Dantas Santos,
Background Global shifts in climatic patterns have been recorded over the last decades. Such modifications mainly correspond to increased temperatures and rainfall regime changes, which are becoming more variable and extreme. Methods We aimed to evaluate the impact of future changes in climatic patterns on the distribution of 19 endemic or threatened bird taxa of the Caatinga. We assessed whether current protected areas (PAs) are adequate and whether they will maintain their effectiveness in the ...
Tópico(s): Animal and Plant Science Education
2023 - PeerJ, Inc. | PeerJ
Produção Nacional
Revisado por pares
Miguel Lino, Érico Leão, André Soares, Carlos Montez, Francisco Vasques, Ricardo Moraes,
The development of flexible and efficient communication mechanisms is of paramount importance within the context of the Internet of Things (IoT) paradigm. IoT has been used for industrial, commercial, and residential applications, and the IEEE 802.15.4/ZigBee standard is one of the most suitable protocols for this purpose. This protocol is now frequently used to implement large-scale Wireless Sensor Networks (WSNs). In industrial settings, it is becoming increasingly common to deploy cluster-tree ...
Tópico(s): Mobile Ad Hoc Networks
2020 - Multidisciplinary Digital Publishing Institute | Sensors
Produção Nacional
Revisado por pares
Priscila Rafaela Leão Soares, André Lucas Corrêa de Andrade, Thamiris Pinheiro Santos, Stephannie Caroline Barros Lucas da Silva, Jadson Freitas da Silva, Amanda Rodrigues dos Santos Magnabosco, Elton Hugo Lima da Silva Souza, Franklin Magliano da Cunha, Valéria Wanderley Teixeira, Marília Ribeiro Sales Cadena, Fabrício Bezerra de Sá, Luiz Bezerra de Carvalho Júnior, Pabyton Gonçalves Cadena,
Lufenuron is a benzoylurea insecticide that interfere in chitin synthesis in insects. Although lufenuron is widely used in agriculture and aquaculture, rare are studies described that relates to possible toxic effects in fish. This work aimed to evaluate acute and chronic toxic effects of benzoylurea pesticide (lufenuron) on biological parameters of Colossoma macropomum (Tambaqui). In the acute test, juveniles of Tambaqui were divided into control group and five experimental groups with exposure from ...
Tópico(s): Aquaculture disease management and microbiota
2016 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
Ivy Bastos Ramis, Margo Cnockaert, Andréa von Groll, Catarina Nogueira, Sylvia Cardoso Leão, Emmanuel André, Anne-Catherine Simon, Juan Carlos Palomino, P. E. A. da Silva, Peter Vandamme, Anandi Martin,
Tópico(s): Antibiotic Resistance in Bacteria
2015 - Springer Science+Business Media | European Journal of Clinical Microbiology & Infectious Diseases
Produção Nacional
Revisado por pares
Ricardo Kim Fukushi Yamada, Gustavo Gonçalves Arliani, Gabriel Peixoto Leão Almeida, André Manrique Venturine, Ciro Veronese dos Santos, Diego Costa Astur, Moisés Cohen,
OBJECTIVE: Most injuries occur during the final 15 minutes of each half of a soccer match, suggesting that physical exertion may influence changes in neuromuscular control and the body's ability to stabilize the joints of the lower extremities.The aim of this study was to analyze the effects of one-half of a soccer match on the functional capacity and stability of the lower limbs in young soccer players. METHODS:We analyzed 27 soccer players by evaluating the functional capacity of their lower limbs ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2012 - Elsevier BV | Clinics
Produção Nacional
Revisado por pares
Sofia C. Nunes, Raquel Sá‐Leão, João André Carriço, Cláudia Alves, R. Mato, A. Brito Avô, Joana Saldanha, Jonas S. Almeida, Ilda Santos‐Sanches, Hermı́nia de Lencastre,
Of the nasopharyngeal cultures recovered from 942 day care center (DCC) attendees in Lisbon, Portugal, 591 (62%) yielded Streptococcus pneumoniae during a surveillance performed in February and March of 1999. Forty percent of the isolates were resistant to one or more antimicrobial agents. In particular, 2% were penicillin resistant and 20% had intermediate penicillin resistance. Multidrug resistance to macrolides, lincosamides, and tetracycline was the most frequent antibiotype (17% of all isolates). ...
Tópico(s): Bacterial Infections and Vaccines
2005 - American Society for Microbiology | Journal of Clinical Microbiology
Produção Nacional
Revisado por pares
Anabela Carvalho Alves, Celina P. Leão, Andre Fernando Uébe Mansur, Maria Inês Ribeiro Albernaz Kury,
This paper presents an exploratory study on the knowledge and importance of integrating Lean Education in curricula from the Academy perspective. The study was based on the analysis of participants' outcomes of workshops settled in international conferences. These workshops were used to promote Lean Education as a fundamental content and competency to be taught to the new professionals, independently of their future activity. Having in their DNA Lean content and competency, professionals will be ...
Tópico(s): Quality and Management Systems
2020 - Taylor & Francis | Production Planning & Control
... 13Makuc J. Paiva S. Schauen M. Kramer R. Andre B. Casal M. Leao C. Boles E. Yeast. 2001; 18: 1131-1143Crossref ... 13Makuc J. Paiva S. Schauen M. Kramer R. Andre B. Casal M. Leao C. Boles E. Yeast. 2001; 18: 1131-1143Crossref ... 13Makuc J. Paiva S. Schauen M. Kramer R. Andre B. Casal M. Leao C. Boles E. Yeast. 2001; 18: 1131-1143Crossref ... 13Makuc J. Paiva S. Schauen M. Kramer R. Andre B. Casal M. Leao C. Boles E. Yeast. 2001; 18: 1131-1143Crossref ... 13Makuc J. Paiva S. Schauen M. Kramer R. Andre B. Casal M. Leao C. Boles E. Yeast. 2001; 18: 1131-1143Crossref ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2005 - Elsevier BV | Journal of Biological Chemistry
Produção Nacional
Revisado por pares
Guilherme Beraldi Lucas, Bruno Albuquerque de Castro, Jorge Alfredo Ardila‐Rey, Adam Głowacz, José Vital Ferraz Leão, André Luiz Andreoli,
Noninvasive fault diagnosis of three-phase induction motors (TIMs) is widely used in industrial applications to ensure the integrity of processes. Among different types of TIM failures, transient interturn short circuits (ITSCs) are incipient stator winding faults characterized as short circuits between two or more turns of the coils, that can lead the winding to progressive deterioration and, consequently, the TIM to total failure. In this context, this article proposes a novel approach by using ...
Tópico(s): Welding Techniques and Residual Stresses
2023 - IEEE Sensors Council | IEEE Sensors Journal
Produção Nacional
Revisado por pares
Pedro Ferreira Torres, André Felipe Pacheco Costa, Vilson Lima Chaar, Weslley Leão Monteiro, Marcos André Barros Galhardo, João Tavares Pinho, Wilson Negrão Macêdo,
Many developing countries that are recently incorporating distributed grid connected photovoltaic systems (GCPVSs) into their electric grid, have a deficit of specialized institutions to carry out activities of teaching, research and training people on this application. Training tools that provide hands-on experience on GCPVSs, allowing the measurement of important parameters in this application, are significant sources of dissemination of this technology. In this context, a mobile, cost-effective, ...
Tópico(s): Photovoltaic System Optimization Techniques
2019 - Elsevier BV | Computers & Electrical Engineering
Produção Nacional
Revisado por pares
Ana Clara Caznok Silveira, André Saraiva Leão Marcelo Antunes, Maria Carolina Pedro Athié, Bárbara Filomena da Silva, João Victor Ribeiro dos Santos, Camila Canateli, Marina Alves Fontoura, Allan Pinto, Luciana Ramalho Pimentel‐Silva, Simoni Helena Avansini, Murilo de Carvalho,
The study of brain connectivity has been a cornerstone in understanding the complexities of neurological and psychiatric disorders. It has provided invaluable insights into the functional architecture of the brain and how it is perturbed in disorders. However, a persistent challenge has been achieving the proper spatial resolution, and developing computational algorithms to address biological questions at the multi-cellular level, a scale often referred to as the mesoscale. Historically, neuroimaging ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2024 - Frontiers Media | Frontiers in Neuroscience
Produção Nacional
Revisado por pares
Fernanda Crunfli, Victor Corasolla Carregari, Flávio P. Veras, Lucas Scárdua Silva, Mateus Henrique Nogueira, André Saraiva Leão Marcelo Antunes, Pedro Henrique Vendramini, Aline Gazzola Fragnani Valença, Caroline Brandão‐Teles, Giuliana S. Zuccoli, Guilherme Reis‐de‐Oliveira, Lícia C. Silva-Costa, Verônica M. Saia‐Cereda, Bradley J. Smith, Ana Campos Codo, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Ícaro Maia Santos de Castro, Bruno Marcel Silva de Melo, Glaucia M. Almeida, Egidi Mayara Silva Firmino, Isadora Marques Paiva, Bruna Manuella Souza Silva, Rafaela Mano Guimarães, Niele Dias Mendes, Raíssa L. Ludwig, Gabriel Palermo Ruiz, Thiago L. Knittel, Gustavo Gastão Davanzo, Jaqueline Aline Gerhardt, Patrícia Brito Rodrigues, Julia Forato, Mariene R. Amorim, Natália S. Brunetti, Matheus Cavalheiro Martini, Maíra Nilson Benatti, Sabrina Setembre Batah, Li Siyuan, Rafael Batista João, Ítalo Karmann Aventurato, Mariana Rabelo de Brito, Maria Julia Mendes, Beatriz Amorim Da Costa, Marina K. M. Alvim, José Roberto da Silva, Lívia Liviane Damião, Iêda Maria Pereira de Sousa, Elessandra Dias da Rocha, Solange Maria Gonçalves, Luiz H. Lopes da Silva, Vanessa Bettini, Brunno Machado de Campos, Guilherme Ludwig, Lucas Tavares, Marjorie Cornejo Pontelli, Rosa Maria Mendes Viana, Ronaldo B. Martins, André Schwambach Vieira, José C. Alves‐Filho, Eurico Arruda, Guilherme Gozzoli Podolsky Gondim, Marcelo Volpon Santos, Luciano Neder, André Damásio, Stevens K. Rehen, Marco Aurélio Ramirez Vinolo, Carolina Demarchi Munhoz, Paulo Louzada‐Júnior, Renê Donizeti Ribeiro de Oliveira, Fernando Q. Cunha, Helder I. Nakaya, Thaís Mauad, Amaro Nunes Duarte‐Neto, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilário Nascimento Saldiva, Alessandro S. Farias, Fernando Cendes, Pedro M. Moraes‐Vieira, Alexandre Todorovic Fabro, Adriano Sebollela, José Luiz Proença-Módena, Clarissa Lin Yasuda, Marcelo A. Mori, Thiago M. Cunha, Daniel Martins‐de‐Souza,
Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently characterized as part of "long COVID-19" syndrome) has been frequently observed after mild infection. We show the spectrum of cerebral impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, ranging from long-term alterations in mildly infected individuals (orbitofrontal cortical atrophy, neurocognitive impairment, ...
Tópico(s): COVID-19 and Mental Health
2022 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Cleiton Barroso Bittencourt, Thalliton Luiz Carvalho da Silva, Jorge Cândido Rodrigues Neto, Letícia Rios Vieira, André Pereira Leão, José Antônio de Aquino Ribeiro, Patrícia Verardi Abdelnur, Carlos Antônio Ferreira de Sousa, Manoel Teixeira Souza,
Oil palm (Elaeis guineensis Jacq.) is the number one source of consumed vegetable oil nowadays. It is cultivated in areas of tropical rainforest, where it meets its natural condition of high rainfall throughout the year. The palm oil industry faces criticism due to a series of practices that was considered not environmentally sustainable, and it finds itself under pressure to adopt new and innovative procedures to reverse this negative public perception. Cultivating this oilseed crop outside the ...
Tópico(s): Coconut Research and Applications
2022 - Multidisciplinary Digital Publishing Institute | Plants
Produção Nacional
Revisado por pares
Danielle Gouvêa-Junqueira, Ana Caroline Brambilla Falvella, André Saraiva Leão Marcelo Antunes, Gabriela Seabra, Caroline Brandão‐Teles, Daniel Martins‐de‐Souza, Fernanda Crunfli,
Oligodendrocytes are the glial cells responsible for the formation of the myelin sheath around axons. During neurodevelopment, oligodendrocytes undergo maturation and differentiation, and later remyelination in adulthood. Abnormalities in these processes have been associated with behavioral and cognitive dysfunctions and the development of various mental illnesses like schizophrenia. Several studies have implicated oligodendrocyte dysfunction and myelin abnormalities in the disorder, together with ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2020 - Frontiers Media | Frontiers in Psychiatry
Produção Nacional
Revisado por pares
Driely Kathriny Monteiro dos Santos, J. Kojima, Thiago Macedo Santana, Diogo Pereira de Castro, Paula Taquita Serra, Naiara Silva Menezes Dantas, Flávio Augusto Leão da Fonseca, Luís André Morais Mariúba, Lígia Uribe Gonçalves,
Tópico(s): Aquatic life and conservation
2020 - Springer Science+Business Media | Aquaculture International
Produção Nacional
Revisado por pares
Gabriela Seabra, Valéria de Almeida, Guilherme Reis‐de‐Oliveira, Fernanda Crunfli, André Saraiva Leão Marcelo Antunes, Daniel Martins‐de‐Souza,
Schizophrenia is a chronic, severe and disabling psychiatric disorder, whose treatment is based on psychosocial interventions and the use of antipsychotic drugs. While the effects of these drugs are well elucidated in neuronal cells, they are still not so clear in oligodendrocytes, which play a vital role in schizophrenia. Thus, we aimed to characterize biochemical profiles by proteomic analyses of human oligodendrocytes (MO3.13) which were matured using a protocol we developed and treated with either ...
Tópico(s): Amino Acid Enzymes and Metabolism
2020 - Nature Portfolio | Scientific Reports
S. Pinto-Magalhães, António Martins, Shirley Silva Lacerda, Rita Filipe, Beatriz Prista‐Leão, Dolores Pinheiro, André Silva‐Pinto, Lurdes Santos,
Candidemia is a nosocomial infection of increasing importance, associated with high morbidity and mortality. The aim of this study is to describe the species distribution, risk factors, management and outcomes of patients with candidemia.We conducted a retrospective study at Centro Hospitalar Universitário de São João, Portugal, between January 2016 and December 2017.A total of 117 candidemia episodes (n=114 patients) were included. Median age was 65 years, with an increased prevalence of older ages. ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2019 - Elsevier BV | Journal de Mycologie Médicale
Carl Rosenblad, Qin Li, Elsa Y. Pioli, Sandra Doveró, André Saraiva Leão Marcelo Antunes, Leticia Agúndez, Martino Bardelli, R. Michael Linden, Els Henckaerts, Anders Björklund, Erwan Bézard, Tomas Björklund,
Abstract Ever since its introduction 40 years ago l-3,4-dihydroxyphenylalanine (l-DOPA) therapy has retained its role as the leading standard medication for patients with Parkinson’s disease. With time, however, the shortcomings of oral l-DOPA treatment have become apparent, particularly the motor fluctuations and troublesome dyskinetic side effects. These side effects, which are caused by the excessive swings in striatal dopamine caused by intermittent oral delivery, can be avoided by delivering ...
Tópico(s): Autism Spectrum Disorder Research
2019 - Oxford University Press | Brain
Julie Tordo, Claire O’Leary, André Saraiva Leão Marcelo Antunes, Nuria Palomar, Patrick Aldrin-Kirk, Mark Basche, Antonette Bennett, Zelpha D’Souza, Hélène F.E. Gleitz, Annie Godwin, Rebecca Holley, Helen Parker, Ai Yin Liao, Paul Rouse, Amir Saam Youshani, Larbi Dridi, C Martins, Thierry Levade, Kevin Stacey, Daniel M. Davis, A. Stephens Dyer, Nathalie Clément, Tomas Björklund, Robin R. Ali, Mavis Agbandje‐McKenna, Rahimin Affandi Abdul Rahim, Alexey V. Pshezhetsky, Simon N. Waddington, R. Michael Linden, Brian Bigger, Els Henckaerts,
Recombinant adeno-associated viruses (AAVs) are popular in vivo gene transfer vehicles. However, vector doses needed to achieve therapeutic effect are high and some target tissues in the central nervous system remain difficult to transduce. Gene therapy trials using AAV for the treatment of neurological disorders have seldom led to demonstrated clinical efficacy. Important contributing factors are low transduction rates and inefficient distribution of the vector. To overcome these hurdles, a variety ...
Tópico(s): Mosquito-borne diseases and control
2018 - Oxford University Press | Brain
Produção Nacional
Revisado por pares
B.R. Correia, Gleidson Giordano Pinto de Carvalho, Ronaldo Lopes Oliveira, Aureliano José Vieira Pires, Ossival Lolato Ribeiro, Robério Rodrigues Silva, André Gustavo Leão, Julliana Izabelle Simionato, Bruna Mara Aparecida de Carvalho,
Peanut cake is a biodiesel byproduct that has been tested as an alternative feed additive for use in cattle production. This study aimed to assess the importance of dietary peanut cake inclusion for young bull growth rate, beef production, and beef quality. In total, 32 Nellore young bulls individually housed in stalls with a mean initial body weight of 390±43.5kg were distributed in a completely randomized design for the experiment. The animals were fed Tifton 85 hay and one of four concentrate ...
Tópico(s): Peanut Plant Research Studies
2016 - Elsevier BV | Meat Science
Produção Nacional
Revisado por pares
Joaquim Bezerra Costa, Ronaldo Lopes Oliveira, Thadeu Mariniello Silva, Rebeca Dantas Xavier Ribeiro, A. M. Silva, André Gustavo Leão, Leílson Rocha Bezerra, Tiago Cunha Rocha,
This study aimed to determine the impact of the inclusion of licuri cake in the diets of crossbred Santa Inês lambs, based on intake, digestibility, N balance, urea N, and performance. We used 44 male lambs that were vaccinated and wormed, with an average age of 6 mo and an average BW of 21.2 kg ± 2.7 kg. The lambs were fed a mixture of Tifton-85 hay (40%) and a concentrated mixture (60%) composed of ground corn, soybean meal, and mineral premix. For the treatments, licuri cake was added at levels of ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2016 - Oxford University Press | Journal of Animal Science
Produção Nacional
Revisado por pares
Fleming Sena Campos, Gleidson Giordano Pinto de Carvalho, Edson Mauro Santos, Gherman Garcia Leal de Araújo, Glayciane Costa Góis, Rodolpho Almeida Rebouças, André Gustavo Leão, Stefanie Alvarenga Santos, Juliana Silva de Oliveira, Laudí Cunha Leite, M. L. G. M. L. de Araújo, Luís Gabriel Alves Cirne, Robério Rodrigues Silva, Bruna Mara Aparecida de Carvalho,
Quality and sensory attributes of meat from 32 mixed-breed Santa Inês lambs fed diets composed of four silages with old man saltbush (Atriplex nummularia Lind), buffelgrass (Cenchrus ciliaris), Gliricidia (Gliricidia sepium), and Pornunça (Manihot sp.) were evaluated. Meat from lambs fed diet containing old man saltbush silage (P 0.05). However, the silages led to differences (P<0.05) in aroma, tenderness, and flavor values. The meat from animals fed the pornunça and Gliricidia silages was tenderer. Flavor ...
Tópico(s): Animal Nutrition and Physiology
2016 - Elsevier BV | Meat Science
Produção Nacional
Revisado por pares
Thadeu Mariniello Silva, Ariosvaldo Nunes de Medeiros, Ronaldo Lopes Oliveira, Severino Gonzaga Neto, Rita de Cássia Ramos do Egypto Queiroga, Rebeca Dantas Xavier Ribeiro, André Gustavo Leão, Leílson Rocha Bezerra,
This study aimed to determine the impact of replacing soybean meal with peanut cake in the diets of crossbred Boer goats as determined by carcass characteristics and quality and by the fatty acid profile of meat. Forty vaccinated and dewormed crossbred Boer goats were used. Goats had an average age of 5 mo and an average BW of 15.6 ± 2.7 kg. Goats were fed Tifton-85 hay and a concentrate consisting of corn bran, soybean meal, and mineral premix. Peanut cake was substituted for soybean meal at levels ...
Tópico(s): Meat and Animal Product Quality
2016 - Oxford University Press | Journal of Animal Science
Produção Nacional
Revisado por pares
Ronaldo Lopes Oliveira, Mário Marcos de Santana Faria, Raimundo Luiz Nunes Vaz da Silva, Leílson Rocha Bezerra, Gleidson Giordano Pinto de Carvalho, Alyson Andrade Pinheiro, Juliana Simionato, André Gustavo Leão,
Lipid supplements (oilseeds vegetables) are included in ruminant diet to increase its energy density and improve fatty acid composition of milk and consequently of fresh cheese. Milk and cheeses were evaluated from crossbred Holstein × Zebu, fed diets enriched with 0%, 25%, 50%, and 75% inclusion levels of palm kernel cake in concentrated supplement, which were supplied daily (3.0 kg). Milk and fresh cheese (p = 0.001) fatty acids C12:0 exhibited quadratic negative values. Milk fatty acids C13:0, C20:0, ...
Tópico(s): Fatty Acid Research and Health
2015 - Multidisciplinary Digital Publishing Institute | Molecules