Maurizio Rizzi, Dejan Radovanovic, Pierachille Santus, Andrea Airoldi, Francesca Frassanito, Silvia Vanni, Andrea Cristiano, Ralph Casale, Raffaello Furlan, Fabiola Atzeni, Piercarlo Sarzi‐Puttini,
Background Fibromyalgia (FM) is characterised by chronic musculoskeletal pain, autonomic nervous system (ANS) dysfunction, and disturbed sleep. Objectives The aim of this study was to evaluate the influence of ANS dysfunction on the genesis of sleep disorders. Methods Fifty consecutive Caucasian women (age 51.2±7.3 years) whose FM had been diagnosed on the basis of the 2010 ACR classification criteria were compared with 45 healthy female controls matched for age and body mass index.All of the FM patients underwent ...
Tópico(s): Cardiovascular Health and Risk Factors
2017 - BMJ | Annals of the Rheumatic Diseases
Enrica T. Tanda, Irene Vanni, Andrea Boutros, Virginia Andreotti, William Bruno, Paola Ghiorzo, Francesco Spagnolo,
Incidence of melanoma has been constantly growing during the last decades. Although most of the new diagnoses are represented by thin melanomas, the number of melanoma-related deaths in 2018 was 60,712 worldwide (Global Cancer Observatory). Until 2011, no systemic therapy showed to improve survival in patients with advanced or metastatic melanoma. At that time, standard of care was chemotherapy, with very limited results. The identification of BRAF V600 mutation, and the subsequent introduction of ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2020 - Frontiers Media | Frontiers in Molecular Biosciences
Michele Abate, Daniele Vanni, Andrea Pantalone, Vincenzo Salini,
Cigarette smoking has deleterious effects on the musculo-skeletal system.The loss of bone mineral content and increased incidence of fractures are the best known negative consequences.The pathogenesis is complex, due to direct toxic effects on osteoblasts/osteoclasts activity of nicotine, and indirect actions on sex and adrenocortical hormones, vitamin D, intestinal calcium absorption, vessels and oxygen supply.Smoking may favour the onset or aggravate the progression of rheumatoid arthritis and ...
Tópico(s): Connective tissue disorders research
2019 - | Muscles Ligaments and Tendons Journal
Camilla Matassini, Costanza Vanni, Andrea Goti, Amelia Morrone, Marco Marradi, Francesca Cardona,
Gold glyconanoparticles (Au GNPs) decorated with the natural iminosugar DAB-1 at different densities are reported.
Tópico(s): Studies on Chitinases and Chitosanases
2018 - Royal Society of Chemistry | Organic & Biomolecular Chemistry
Daniele Vanni, Andrea Pantalone, Vincenzo Magliani, Vincenzo Salini, Pedro Berjano,
To evaluate the role of third generation percutaneous vertebral augmentation systems (Spine Jack®) as alternative to the corpectomies and expandable cages replacement (X-Core® Adjustable VBR System) in the treatment of vertebra plana (VP) as complication of the osteoporosis vertebral fracture (OVF).Spine Jack® is a new device for mechanical kyphoplasty (MK). It is a titanium implant designed to restore the height of the vertebral body in OVF, primary or secondary bone tumors, or traumatic fractures. ...
Tópico(s): Scoliosis diagnosis and treatment
2017 - AME Publishing Company | Journal of Spine Surgery
Vincenzo Salini, Daniele Vanni, Andrea Pantalone, Michele Abate,
Platelet Rich Plasma (PRP) has shown positive and long-lasting effects in patients with tendinopathies. However, information about age-related differences in the clinical outcome is limited. Aim of this retrospective study was to compare the efficacy of PRP therapy in young and elderly subjects suffering for Achilles tendinopathy.Patients with recalcitrant non-insertional Achilles tendinopathy were enrolled. Clinical (VISA-A) and instrumental (ultrasonography) data were collected at baseline and after ...
Tópico(s): Sports injuries and prevention
2015 - Frontiers Media | Frontiers in Aging Neuroscience
Ester Vanni, Andrea Marengo, L. Mezzabotta, Elisabetta Bugianesi,
The top three leading causes of death in patients with nonalcoholic fatty liver disease (NAFLD) in descending order are cardiovascular disease, cancer, and liver disease. It is clear now that the increased risk of metabolic and macro- and microvascular complications in NAFLD stems from the associated features of metabolic syndrome. However, NAFLD itself may contribute to the spectrum of risk factors associated with insulin resistance. The primary focus of this review is to summarize the main systemic ...
Tópico(s): Hepatitis C virus research
2015 - Thieme Medical Publishers (Germany) | Seminars in Liver Disease
Michele Abate, Tommaso Scuccimarra, Daniele Vanni, Andrea Pantalone, Vincenzo Salini,
Tópico(s): Cardiac Valve Diseases and Treatments
2013 - Springer Science+Business Media | Knee Surgery Sports Traumatology Arthroscopy
Vincenzo Salini, Daniele Vanni, Andrea Pantalone, Francesco Bigossi, Filippo Pineto, D Lucantoni,
Introduction: The prevalence of osteoporotic vertebral fractures (OVF) increased in the last years. Compression fractures promote a progressive spine kyphosis increase, resulting in a weight shift and anterior column overload, with OVF additional risk (domino effect). The aim of this study is to evaluate the OVF treatment outcome using Spine Jack ®, a titanium device for third generation percutaneous vertebral augmentation procedures (PVAPs). Materials and Methods: From February 2010, a prospective randomized ...
Tópico(s): Pelvic and Acetabular Injuries
2012 - Medknow | Journal of Craniovertebral Junction and Spine
Daniele Vanni, Andrea Pantalone, Elda Andreoli, P. Caldora, Vincenzo Salini,
Abstract Introduction Several cases of long bone giant cell tumor have been reported in the literature. We report the case of a patient with a giant cell tumor in the distal ulna. This is very unusual, with a reported incidence of 0.45 to 6%. Case presentation A 17-year-old Colombian man presented with a painful swelling of the left wrist. After performing an instrumental examination, a diagnosis of distal ulna giant cell tumor was made. The tumor was treated with an intralesional curettage, phenol ...
Tópico(s): Sarcoma Diagnosis and Treatment
2012 - BioMed Central | Journal of Medical Case Reports
The distribution of stresses in rigid colloidal aggregates under a shear flow was investigated numerically for particle–cluster and cluster–cluster aggregates with fractal dimensions ranging from 1.7 to 2.3. Stokesian dynamics was used to calculate the hydrodynamic force on each monomer, while the internal intermonomer interactions were calculated by applying force and torque balances on each primary particle. Although the hydrodynamic forces act mainly on the periphery of the clusters, their filamentous ...
Tópico(s): Granular flow and fluidized beds
2011 - American Chemical Society | Langmuir
Roberto Puglisi, Roberta Vanni, Andrea Galli, Donatella Balduzzi, Katia Parati, Graziella Bongioni, G. Crotti, Roberto Duchi, Cesare Galli, Giovanna Lazzari, R. Aleandri,
The methodologies used for cytometric sorting of fresh spermatozoa never allowed a clear resolution of sexual chromosomes of frozen-thawed semen. To devise a novel method for the production of bovine predefined sexed embryos using frozen-thawed semen, sorting efficiency of different protocols was studied using a new quantitative real-time PCR method to verify the purity of sexed semen. To this aim, after Percoll separation, frozen-thawed samples were stained at different temperatures and concentrations ...
Tópico(s): Reproductive Physiology in Livestock
2006 - Bioscientifica | Reproduction
Michele Abate, Daniele Vanni, Andrea Pantalone, Vincenzo Salini,
Aim To evaluate the therapeutic trajectory of intra-articular injections of hyaluronic acid at high concentration (2%) performed at 4-month intervals. Methods Subjects with knee osteoarthritis received, after a weekly injection of 32 mg/2 mL hyaluronic acid for 3 weeks, a single injection of 50 mg/2.5 mL hyaluronic acid (not cross-linked, molecular weight 800–1200 kDa) at 4-month interval (4, 8 and 12 months). Clinical assessment (visual analogic scale [VAS] for pain at rest and during activities, Lequesne ...
Tópico(s): Advancements in Transdermal Drug Delivery
2015 - Wiley | International Journal of Rheumatic Diseases
Massimiliano Caprio, Elisa Fabbrini, Giulia Ricci, Sabrina Basciani, Lucio Gnessi, Mario Arizzi, Anna R. Carta, Massimo U. De Martino, Andrea M. Isidori, Giovanni Vanni Frajese, Andrea Fabbri,
There are still many controversies about the role of leptin in reproductive function and sexual development. We recently demonstrated that leptin receptors are expressed in rodent Leydig cells and that leptin has inhibitory effects on hCG-stimulated testosterone production by adult rat Leydig cells in culture. In this study, we evaluated the expression of leptin receptor (Ob-R) in rat testes from gestational to adult age in comparison with the pattern of expression of relaxin-like factor (RLF), a ...
Tópico(s): Pregnancy-related medical research
2003 - Oxford University Press | Biology of Reproduction
Cristina Mussini, Roberto Bugarini, Carlo Federico Perno, Andrea Antinori, Vanni Borghi, Ada Bertoli, Roberta D’Arrigo, Andrea Bedini, Nicola Mongiardo, Andrea Cossarizza, Roberto Esposito,
... discontinuation. Cristina Mussinia Roberto Bugarinib Carlo Federico Pernoc Andrea Antinoric Vanni Borghia Ada Bertolic Roberta D'Arrigoc Andrea Bedinia Nicola Mongiardoa Andrea Cossarizzad Roberto Espositoa Acknowledgements ...
Tópico(s): HIV/AIDS Research and Interventions
2002 - Lippincott Williams & Wilkins | AIDS
Angela Rampa, Lorna Piazzi, Federica Belluti, Silvia Gobbi, Alessandra Bisi, Manuela Bartolini, Vincenza Andrisano, Vanni Cavrini, Andrea Cavalli, Maurizio Recanatini, Piero Valenti,
In this work, we further investigated a class of carbamic cholinesterase inhibitors introduced in a previous paper (Rampa et al. J. Med. Chem. 1998, 41, 3976). Some new ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl analogues were designed, synthesized, and evaluated for their inhibitory activity against both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). The structure of the lead compound (xanthostigmine) was systematically varied with the aim to optimize the different ...
Tópico(s): Enzyme function and inhibition
2001 - American Chemical Society | Journal of Medicinal Chemistry
Angela Rampa, Alessandra Bisi, Federica Belluti, Silvia Gobbi, Piero Valenti, Vincenza Andrisano, Vanni Cavrini, Andrea Cavalli, Maurizio Recanatini,
Tópico(s): Chemical synthesis and alkaloids
2000 - Elsevier BV | Bioorganic & Medicinal Chemistry
Cristina Mussini, Patrizio Pezzotti, Alessandra Govoni, Vanni Borghi, Andrea Antinori, Antonella d'Arminio Monforte, Andrea De Luca, Nicola Mongiardo, Maria Chiara Cerri, Francesco Chiodo, Ercole Concia, L Bonazzi, Mauro Moroni, L Ortona, Roberto Esposito, Andrea Cossarizza, Bruno De Rienzo,
A multicenter open, randomized, controlled trial was conducted to determine whether primary prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis can be discontinued in patients infected with human immunodeficiency virus type 1 (HIV-1) whose CD4+ T cell counts have increased to >200 cells/mm3 (and who have remained at this level for at least 3 months) as a result of highly active antiretroviral therapy (HAART). Patients were randomized to either the discontinuation arm (i.e., those ...
Tópico(s): HIV/AIDS Research and Interventions
2000 - Oxford University Press | The Journal of Infectious Diseases
Simona Ceglia, Alyssa Berthelette, Kelsey Howley, Yun Li, Benedikt M. Mortzfeld, Shakti K. Bhattarai, Nicole K.H. Yiew, Ying Xu, Robert Brink, Jason G. Cyster, Lora V. Hooper, Gwendalyn J. Randolph, Vanni Bucci, Andrea Reboldi,
Immunoglobulin A (IgA) secretion by plasma cells, terminally differentiated B cells residing in the intestinal lamina propria, assures microbiome homeostasis and protects the host against enteric infections. Exposure to diet-derived and commensal-derived signals provides immune cells with organizing cues that instruct their effector function and dynamically shape intestinal immune responses at the mucosal barrier. Recent data have described metabolic and microbial inputs controlling T cell and innate ...
Tópico(s): T-cell and B-cell Immunology
2023 - Nature Portfolio | Nature Immunology
Arturo Ciccullo, Vanni Borghi, Andrea Giacomelli, Maria Vittoria Cossu, Gaetana Sterrantino, Alessandra Latini, Maria Carla Re, Andrea De Vito, William Gennari, Giordano Madeddu, Amedeo Capetti, Gabriella d’Ettorre, Cristina Mussini, Stefano Rusconi, Simona Di Giambenedetto, Gianmaria Baldin,
Results from clinical trials and observational studies suggest that dolutegravir plus lamivudine could be an effective and well-tolerated option for simplification in HIV-1-positive patients. We aimed to assess long-time efficacy and safety in our multicenter cohort.This was a retrospective study enrolling HIV-1-infected, virologically suppressed patients switching to dolutegravir + lamivudine. We performed survival analysis to evaluate time to virological failure (VF, defined by a single HIV-RNA ≥1000 ...
Tópico(s): HIV/AIDS Research and Interventions
2021 - Lippincott Williams & Wilkins | JAIDS Journal of Acquired Immune Deficiency Syndromes
Davide Ferrari, Jovana Milić, Roberto Tonelli, Francesco Ghinelli, Marianna Meschiari, Sara Volpi, Matteo Faltoni, Giacomo Franceschi, Vittorio Iadisernia, Dina Yaacoub, Giacomo Ciusa, Erica Bacca, Carlotta Rogati, Marco Tutone, Giulia Burastero, Alessandro Raimondi, Marianna Menozzi, Erica Franceschini, Gianluca Cuomo, Luca Corradi, Gabriella Orlando, Antonella Santoro, Margherita Digaetano, Cinzia Puzzolante, Federica Carli, Vanni Borghi, Andrea Bedini, Riccardo Fantini, Luca Tabbì, Ivana Castaniere, Stefano Busani, Enrico Clini, Massimo Girardis, Mario Sarti, Andrea Cossarizza, Cristina Mussini, Federica Mandreoli, Paolo Missier, Giovanni Guaraldi,
Aims The aim of this study was to estimate a 48 hour prediction of moderate to severe respiratory failure, requiring mechanical ventilation, in hospitalized patients with COVID-19 pneumonia. Methods This was an observational prospective study that comprised consecutive patients with COVID-19 pneumonia admitted to hospital from 21 February to 6 April 2020. The patients’ medical history, demographic, epidemiologic and clinical data were collected in an electronic patient chart. The dataset was used ...
Tópico(s): Sepsis Diagnosis and Treatment
2020 - Public Library of Science | PLoS ONE
Luca Ansaloni, Vanni Agnoletti, Andrea Amadori, Fausto Catena, Davide Cavaliere, Federico Coccolini, Pierandrea De Iaco, Monica Di Battista, Massimo Framarini, Filippo Gazzotti, Claudio Ghermandi, Barbara Kopf, Maristella Saponara, Francesca Tauceri, Carlo Vallicelli, Giorgio Maria Verdecchia, Antonio Daniele Pinna,
Although standard treatment for advanced epithelial ovarian cancer (EOC) consists of surgical debulking and intravenous platinum- and taxane-based chemotherapy, favorable oncological outcomes have been recently reported with the use of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The aim of the study was to analyze feasibility and results of CRS and HIPEC in patients with advanced EOC.This is an open, prospective phase 2 study including patients with primary or ...
Tópico(s): Uterine Myomas and Treatments
2012 - BMJ | International Journal of Gynecological Cancer
Marilena Cozzolino, Elisa Di Giovanni, Paolo Mauriello, Andrea Vanni Desideri, D. Patella,
ABSTRACT Within this article are the results of a geoelectrical survey performed in the park of Pratolino at Vaglia (Florence, Italy), using the multiple dipole–dipole profile technique. The purpose was to outline the location of the main body of the ancient Villa Medici di Pratolino, of which only a separate building, now known as Villa Demidoff, is visible in its full splendour. The three‐dimensional probability‐based electrical resistivity tomography inversion (PERTI) approach has been adopted. ...
Tópico(s): Seismic Waves and Analysis
2012 - Wiley | Archaeological Prospection
Elisa Nemes, Linda Bertoncelli, Enrico Lugli, Marcello Pinti, Milena Nasi, Lisa Manzini, Serena Manzini, Francesca Prati, Vanni Borghi, Andrea Cossarizza, Cristina Mussini,
Background: The activity of virus-specific T lymphocytes, among which those capable of a polyfunctional response against the viral protein gag, is crucial to control HIV infection. Objective: The objective of this study is to investigate the polyfunctionality of gag-specific T cells in different phases of HIV infection, analyzing markers related to T-helper cell 1 (Th1) and degranulation/cytotoxicity, and the production of Th1 cytokines in peripheral blood lymphocytes from patients experiencing an ...
Tópico(s): HIV/AIDS Research and Interventions
2010 - Lippincott Williams & Wilkins | AIDS
Cristina Mussini, Patrizio Pezzotti, José M. Miró, Estebán Martínez, Juan Carlos Lopez Bernaldo de Quirós, Paola Cinque, Vanni Borghi, Andrea Bedini, Peré Domingo, Pedro Cahn, Philippe Bossi, Andrea De Luca, Antonella d’Arminio Monforte, Mark Nelson, Nneka Nwokolo, Silvia Helou, Ricardo Negroni, Gaia Jacchetti, Spinello Antinori, Adriano Lazzarin, Andrea Cossarizza, Roberto Esposito, Andrea Antinori, Judith A. Aberg,
We conducted a retrospective, multicenter study evaluating the safety of discontinuing maintenance therapy for cryptococcal meningitis after immune reconstitution. Inclusion criteria were a previous definitive diagnosis of cryptococcal meningitis, a CD4 cell count of >100 cells/µL while receiving highly active antiretroviral therapy (HAART), and the subsequent discontinuation of maintenance therapy for cryptococcal meningitis. The primary end point was relapse of cryptococcal disease. As of July 2002, ...
Tópico(s): HIV/AIDS oral health manifestations
2004 - Oxford University Press | Clinical Infectious Diseases
Carlo Melchiorre, Vincenza Andrisano, María Laura Bolognesi, Roberta Budriesi, Andrea Cavalli, Vanni Cavrini, Michela Rosini, Vincenzo Tumiatti, Maurizio Recanatini,
... Melchiorre, Vincenza Andrisano, Maria L. Bolognesi, Roberta Budriesi, Andrea Cavalli, Vanni Cavrini, Michela Rosini, Vincenzo Tumiatti, and Maurizio RecanatiniView ...
Tópico(s): Computational Drug Discovery Methods
1998 - American Chemical Society | Journal of Medicinal Chemistry
Laura Masuelli, Enrica Di Stefano, Massimo Fantini, Rosanna Mattera, Monica Benvenuto, Laura Marzocchella, Pamela Sacchetti, Chiara Focaccetti, Roberta Bernardini, Ilaria Tresoldi, Valerio Izzi, Maurizio Mattei, Giovanni Vanni Frajese, Florigio Lista, Andrea Modesti, Roberto Bei,
... 2 , Valerio Izzi 2 , Maurizio Mattei 3 , Giovanni Vanni Frajese 4 , Florigio Lista 5 , Andrea Modesti 2 and Roberto Bei 2 1 Department ...
Tópico(s): Sirtuins and Resveratrol in Medicine
2014 - Impact Journals LLC | Oncotarget
Elda Andreoli, Andrea Troiani, Valentina Tucci, Gina Barlafante, Francesco Cerritelli, Gianfranco Pizzolorusso, Cinzia Renzetti, Daniele Vanni, Andrea Pantalone, Vincenzo Salini,
Treatment recommendations for congenital talipes equinovarus are focused on conservative treatments.The aim of this paper is to present a case report of bilateral congenital talipes equinovarus treated with two short-leg serial casting in combination with osteopathic manipulative treatment.A newborn, 12 days old, with severe bilateral congenital talipes equinovarus entered to the Department of Orthopedics at the University of Chieti, Italy. The pediatric orthopedic surgeon applied two single series ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2013 - Elsevier BV | Journal of Bodywork and Movement Therapies
Edgardo Somigliana, Valeria Stella Vanni, Andrea Busnelli, Marco Reschini, Enrico Papaleo, Paola Viganò,
Tópico(s): Reproductive Biology and Fertility
2018 - Oxford University Press | Human Reproduction Update
Cristina Mussini, Patrizio Pezzotti, Andrea Antinori, Vanni Borghi, Antonella d’Arminio Monforte, Alessandra Govoni, Andrea De Luca, Adriana Ammassari, Nicola Mongiardo, Maria Chiara Cerri, Andrea Bedini, Cristina Beltrami, Maria Alessandra Ursitti, Teresa Bini, Andrea Cossarizza, Roberto Esposito,
To evaluate whether bacterial vaginosis predicts the acquisition of sexually transmitted diseases (STDs), we studied 255 nonpregnant female subjects aged 15–30 who reported recent sexual contact with a male partner in whom either gonococcal or chlamydial urethritis or nongonococcal urethritis was diagnosed. Compared to subjects with normal vaginal flora, subjects with bacterial vaginosis were more likely to test positive for Neisseria gonorrhoeae (odds ratio [OR], 4.1; 95% confidence interval [CI], ...
Tópico(s): HIV/AIDS drug development and treatment
2003 - Oxford University Press | Clinical Infectious Diseases