Wolfram Lamadé, Christoph Ulmer, Andreas Seimer, Viktor Molnar, Uta Meyding‐Lamadé, Klaus‐Peter Thon, Klaus Peter Koch,
Existing nerve monitoring devices in thyroid surgery are ‐ except for one ‐ mainly intermittently working nerve identification tools. We present a new vagal electrode which allows true continuous monitoring of the recurrent laryngeal nerve (RLN). The electrode was designed as a tripolar hybrid cuff electrode consisting of polyimide, gold and platinum layers embedded in a flexible silicon cuff which can be opened at the long side for introducing the nerve. It is fully implantable and atraumatic. The evoked ...
Tópico(s): Airway Management and Intubation Techniques
2007 - Taylor & Francis | Minimally Invasive Therapy & Allied Technologies
Michael Joannidis, Jordan Kountchev, Markus Rauchenzauner, Nicola Schusterschitz, Hanno Ulmer, Andreas Mayr, Romuald Bellmann,
Tópico(s): Central Venous Catheters and Hemodialysis
2007 - Springer Science+Business Media | Intensive Care Medicine
Felix Streichert, Gunnar Stein, Holger Ulmer, Andreas Zell,
Tópico(s): Data Mining Algorithms and Applications
2003 - Springer Science+Business Media | Lecture notes in computer science
B Schneider, A. Thanhäuser, D. Jocham, Harald Loppnow, E Vollmer, Joerg Galle, H.‐D. Flad, A.J. Ulmer, Andreas Böhle,
Tópico(s): Amino Acid Enzymes and Metabolism
1994 - Springer Science+Business Media | World Journal of Urology
Ralf Linke, M. Ulmer, Andreas B. Imhoff,
Tópico(s): Bone fractures and treatments
2006 - Springer Nature | Operative Orthopädie und Traumatologie
E. Hennes, Sibylle Zotter, Ludwig Dorninger, Hans Hartmann, Martin Häusler, Peter Huppke, Julia Jacobs, Verena Kraus, C. Makowski, Kurt Schlachter, Hanno Ulmer, Andreas van Baalen, Johannes Koch, T. Gotwald, Kevin Rostásy,
Background Acute cerebellitis (AC) is characterized by cerebellar symptoms and magnetic resonance imaging (MRI) changes primarily confined to the cerebellum. Objective To analyze the neurological and cognitive long-term outcome of children with AC. Methods Children with AC diagnosed by typical clinical features and MRI findings were included in this retrospective study. Medical charts were reviewed and neurological deficits were assessed by neurological examination or by the expanded disability status scale ...
Tópico(s): Infectious Encephalopathies and Encephalitis
2012 - Thieme Medical Publishers (Germany) | Neuropediatrics
Felix Streichert, Holger Ulmer, Andreas Zell,
While single-objective Evolutionary Algorithms (EAs) parallelization schemes are both well established and easy to implement, this is not the case for Multi-Objective Evolutionary Algorithms (MOEAs). Nevertheless, the need for parallelizing MOEAs arises in many real-world applications, where fitness evaluations and the optimization process can be very time consuming. In this paper, we test the ‘divide and conquer’ approach to parallelize MOEAs, aimed at improving the speed of convergence beyond a parallel ...
Tópico(s): Evolutionary Algorithms and Applications
2005 - Springer Science+Business Media | Lecture notes in computer science
Felix Streichert, Holger Ulmer, Andreas Zell,
While the unconstrained portfolio optimization problem can be solved efficiently by standard algorithms, this is not the case for the portfolio optimization problem with additional real world constraints like cardinality constraints, buy-in thresholds, roundlots etc. In this paper we investigate two extensions to Evolutionary Algorithms (EA) applied to the portfolio optimization problem. First, we introduce a problem specific EA representation and then we add a local search for feasible solutions ...
Tópico(s): Scheduling and Optimization Algorithms
2004 - Springer Nature | Operations research proceedings
Felix Streichert, Holger Ulmer, Andreas Zell,
In financial engineering the problem of portfolio selection has drawn much attention in the last decades. But still unsolved problems remain, while on the one hand the type of model to use is still debated, even the most common models cannot be solved efficiently, if real world constraints are added. This is not only because the portfolio selection problem is multi-objective, but also because constraints may turn a formerly continuous problem into a discrete one. Therefore, we suggest to use a Multi- ...
Tópico(s): Metaheuristic Optimization Algorithms Research
2004 - Springer Science+Business Media | Lecture notes in computer science
Felix Streichert, Gunnar Stein, Holger Ulmer, Andreas Zell,
We propose a new niching method for Evolutionary Algorithms which is able to identify and track global and local optima in a multimodal search space. To prevent the loss of diversity we replace the global selection pressure within a single population by local selection of a multi-population strategy. The sub-populations representing species specialized on niches are dynamically identified using standard clustering algorithms on a primordial population. With this multi-population strategy we are ...
Tópico(s): Data Management and Algorithms
2004 - Springer Science+Business Media | Lecture notes in computer science
Felix Streichert, Hannes Planatscher, Christian Spieth, Holger Ulmer, Andreas Zell,
In recent years several strategies for inferring gene regulatory networks from observed time series data of gene expression have been suggested based on Evolutionary Algorithms. But often only few problem instances are investigated and the proposed strategies are rarely compared to alternative strategies. In this paper we compare Evolution Strategies and Genetic Programming with respect to their performance on multiple problem instances with varying parameters. We show that single problem instances ...
Tópico(s): Viral Infectious Diseases and Gene Expression in Insects
2004 - Springer Science+Business Media | Lecture notes in computer science
Karl Peter Rheinwalt, Uta Drebber, Robert Schierwagen, Sabine Klein, Ulf P. Neumann, Tom Florian Ulmer, Andreas Plamper, Andreas Kroh, Sandra Schipper, Margarete Odenthal, Frank Erhard Uschner, Philipp Lingohr, Jonel Trebicka, Maximilian Joseph Brol,
Bariatric surgery is a widely used treatment for morbid obesity. Prediction of postoperative weight loss currently relies on prediction models, which mostly overestimate patients' weight loss. Data about the influence of Non-alcoholic fatty liver disease (NAFLD) on early postoperative weight loss are scarce.This prospective, single-center cohort study included 143 patients receiving laparoscopic gastric bypass surgery (One Anastomosis-Mini Gastric Bypass (OAGB-MGB) or Roux-en-Y Gastric Bypass (RYGB)). ...
Tópico(s): Cardiovascular Disease and Adiposity
2020 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Wegene Borena, Zoltán Bánki, Katie Bates, Hannes Winner, Lydia Riepler, Annika Rössler, Lisa Pipperger, Igor Theurl, Barbara Falkensammer, Hanno Ulmer, Andreas Walser, Daniel Pichler, Matthias R. Baumgartner, Sebastian Schönherr, Lukas Forer, Ludwig Knabl, Reinhard Würzner, Dorotheé von Laer, Jörg Paetzold, Janine Kimpel,
Background In early March 2020, a SARS-CoV-2 outbreak in the ski resort Ischgl in Austria triggered the spread of SARS-CoV-2 throughout Austria and Northern Europe. In a previous study, we found that the seroprevalence in the adult population of Ischgl had reached 45% by the end of April, representing an exceptionally high level of local seropositivity in Europe. We performed a follow-up study in Ischgl, which is the first to show persistence of immunity and protection against SARS-CoV-2 and some ...
Tópico(s): COVID-19 epidemiological studies
2021 - Elsevier BV | EBioMedicine
Thomas Waldow, Wolfgang Witt, André Ulmer, Andreas Janke, Konstantin Alexiou, Klaus Matschke,
Since the generation of nitric oxide (NO) is an essential step in the trigger phase of ischemic preconditioning, short-term inhalation of NO before ischemia should ameliorate ischemia/reperfusion (I/R) injury of the lung. We tested this hypothesis in high oxygen (>99%) ventilated rats in order to additionally evaluate compatibility of NO and exposure to hyperoxia. Male adult Sprague–Dawley rats inhaled NO (15 ppm, 10 min) before the left lung hilum was clamped for 1 h, and the reperfusion phase was observed ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2007 - Elsevier BV | Pulmonary Pharmacology & Therapeutics
Felix Streichert, Christian Spieth, Holger Ulmer, Andreas Zell,
In this paper we address the problem of limited growth and the difficulty of self-repairing in the field of Artificial Embryology. For this purpose, we developed a topological simulation environment for multiple cells which is continuous and structure-oriented, with a dynamically connected network of growing cells and endogenous communication between these cells. The cell behavior is simulated based on models of gene regulatory networks like Random Boolean Networks and S-Systems. Evolutionary Algorithms ...
Tópico(s): Gene Regulatory Network Analysis
2003 - Springer Science+Business Media | Lecture notes in computer science
Ralf Linke, M. Ulmer, Andreas B. Imhoff,
Tópico(s): Bone fractures and treatments
2007 - Springer Science+Business Media | European Journal of Trauma and Emergency Surgery
Pascal Müller, Peter Wonka, Simon Haegler, Andreas Ulmer, Luc Van Gool,
CGA shape , a novel shape grammar for the procedural modeling of CG architecture, produces building shells with high visual quality and geometric detail. It produces extensive architectural models for computer games and movies, at low cost. Context sensitive shape rules allow the user to specify interactions between the entities of the hierarchical shape descriptions. Selected examples demonstrate solutions to previously unsolved modeling problems, especially to consistent mass modeling with volumetric ...
Tópico(s): Architecture and Computational Design
2006 - Association for Computing Machinery | ACM Transactions on Graphics
Joachim von Wulffen, Andreas Ulmer, Günter Jäger, Oliver Sawodny, Ronny Feuer,
Escherichia coli is able to shift between anaerobic and aerobic metabolism by adapting its gene expression, e.g., of metabolic genes, to the new environment. The dynamics of gene expression that result from environmental shifts are limited, amongst others, by the time needed for regulation and transcription elongation. In this study, we examined gene expression dynamics after an anaerobic-to-aerobic shift on a short time scale (0.5, 1, 2, 5, and 10 min) by RNA sequencing with emphasis on delay times ...
Tópico(s): RNA and protein synthesis mechanisms
2017 - Multidisciplinary Digital Publishing Institute | Genes
Christiana Schernthaner, Matthias Hammerer, Stefan Harb, Matthias Heigert, K. Hoellinger, Elisabeth Laßnig, E. Maurer, Jochen Schuler, Peter Siostrzonek, Hanno Ulmer, Andreas Winter, Johann Altenberger,
Tópico(s): Acute Myocardial Infarction Research
2017 - Springer Science+Business Media | Wiener klinische Wochenschrift
Wilfried Schgoer, Kathrin Eller, Thomas Mueller, Ivan Tancevski, Andreas Wehinger, Hanno Ulmer, A. Sandhofer, Andreas Ritsch, Meinhard Haltmayer, Josef R. Patsch,
Microsomal triglyceride transfer protein (MTP) transfers lipids into apoprotein B-containing lipoproteins for secretion from liver, intestine, and heart. We hypothesized the -493T single nucleotide polymorphism in the MTP promoter region to be associated with altered lipoprotein levels and with presence of peripheral arterial disease (PAD).433 patients with symptomatic PAD and 433 controls matched for sex and age from the Linz Peripheral Arterial Disease (LIPAD) study were genotyped cross-sectionally ...
Tópico(s): Aortic aneurysm repair treatments
2008 - Elsevier BV | Clinical Biochemistry
Stephan Ulmer, Katharina Flemming, Andreas Hahn, Ulrich Stephani, O Jansen,
Alpers-Huttenlocher syndrome (AHS) is a rare mitochondrial disorder of childhood onset that is characterized by progressive encephalopathy and hepatopathy. MRI studies are rare and have not added substantial information to the pathogenesis of the encephalopathy. Diffusion-weighted MRI (DWI) and MR spectroscopy (MRS) were used in a patient with AHS during acute clinical deterioration and after improvement. DWI detected signal hyperintensity in several brain areas not restricted to any vascular territory. ...
Tópico(s): Metabolism and Genetic Disorders
2002 - Lippincott Williams & Wilkins | Journal of Computer Assisted Tomography
Anja Ulmer, Ina Kötter, Andreas Pfaffc, Gerhard Fierlbeck,
We describe a 69-year-old patient with long-standing mixed connective tissue disease who suffered from severe skin eruptions that did not respond to various immunosuppressive regimens. Therapy with high-dose intravenous immunoglobulin was successful in controlling the patient's disease without major side effects. We think that this regimen—although expensive—might be an interesting therapeutic option in selected patients with mixed connective tissue disease that is refractory to other treatment ...
Tópico(s): Inflammatory Myopathies and Dermatomyositis
2002 - Elsevier BV | Journal of the American Academy of Dermatology
Katharina Flemming, S. Ulmer, Barbara Duisberg, Andreas Hahn, Olav Jansen,
Alpers-Huttenlocher syndrome, considered a mitochondrial disease, combines encephalopathy and liver failure. An 11-year-old boy with Alpers-Huttenlocher syndrome underwent conventional MR imaging, diffusion-weighted imaging, and proton MR spectroscopy. Diffusion-weighted imaging showed cytotoxic edema interpreted as acute-phase encephalopathy. MR spectroscopy revealed a lactate peak in the cortex that appeared abnormal on diffusion-weighted images, possibly representing respiratory deficiency with ...
Tópico(s): Metabolism and Genetic Disorders
2002 - American Society of Neuroradiology | American Journal of Neuroradiology
Holger Ulmer, Felix Streichert, Andreas Zell,
The task of speeding up the optimization process on problems with very time consuming fitness functions is a central point in evolutionary computation. Applying models as a surrogate of the real fitness function is a quite popular idea. The performance of this approach is highly dependent on the frequency of how often the model is updated with data from new fitness evaluations. However, in generation based algorithms this is only done every λ-th fitness evaluation. To overcome this problem we use ...
Tópico(s): Advanced Multi-Objective Optimization Algorithms
2003 - Springer Science+Business Media | Lecture notes in computer science
Ulrich Ulmer, Kohta Asano, Andreas Patyk, Hirotoshi Enoki, Yumiko Nakamura, Alexander Pohl, Roland Dittmeyer, Maximilian Fichtner,
Microstructural changes, thermodynamic and cyclic properties, total material cost and the cumulative energy demand of V(40−40·x)Fe(8−8·x)Ti26Cr26(FeV)(48·x) with 0 ≤ x ≤ 0.9 using commercial ferrovanadium (FeV) are investigated. The substitution of V + Fe by FeV (x = 0.9) raises the equilibrium hydrogen pressure at 298 K from pa = 1 MPa to pa = 6 MPa during absorption of H2 and pd = 0.2 MPa and pd = 1 MPa during desorption. The reversible hydrogen storage capacity is determined after 50 pressure-swing cycles and ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
2015 - Elsevier BV | Journal of Alloys and Compounds
Anna Ulmer, Christoph Brunner, Andreas M. Arnold, Alexander Pöthig, Tanja Gulder,
Fluorinated organic molecules are of high interest for many applications across chemical and medical disciplines. Efficient methods for the synthesis of such compounds are thus needed. Within this work, application of the bench-stable cyclic hypervalent iodine(III) fluoro reagent 1 facilitated the development of an efficient, metal-free method for the preparation of the novel class of 4-fluoro-1,3-benzoxazepines starting from readily available styrenes. The efficacy and broad applicability of this ...
Tópico(s): Synthesis and Biological Evaluation
2015 - Wiley | Chemistry - A European Journal
Lilli Scheiterle, Alina Ulmer, Regina Birner, Andreas Pyka,
The shift from a fossil-based to a bio-based economy (bioeconomy) requires more efficient utilization of the biomass generated from agricultural production. This can be achieved through the cascading use of biomass, which also offers the potential of creating additional value from biomass by developing novel products. Taking sugarcane as a case study example, this paper aims to analyze how well Brazil, the world’s leader in sugarcane production, is positioned to reach these goals. The paper combines ...
Tópico(s): Innovation and Socioeconomic Development
2017 - Elsevier BV | Journal of Cleaner Production
Antje Wilke, Kirsten Langfeld, Bernhard Ulmer, Vlad Andrievici, Andreas Hörold, Patrick A. Limbach, Martin Bastian, Bernhard Schartel,
Developing flame retarded thermoplastic elastomers (TPE-S) based on styrene–ethylene–butylene–styrene, polypropylene, and mineral oil is a challenging task because of their very high fire loads and flammability. A promising approach is the synergistic combination of expandable graphite (EG) and ammonium polyphosphate (APP). Cone calorimetry, oxygen index, and UL 94 classification were applied. The optimal EG:APP ratio is 3:1, due to the most effective fire residue morphology. Exchanging APP with melamine- ...
Tópico(s): Polymer Nanocomposites and Properties
2017 - American Chemical Society | Industrial & Engineering Chemistry Research
Kathrin Eller, Wilfried Schgoer, Thomas Mueller, Ivan Tancevski, Andreas Wehinger, Hanno Ulmer, Bernhard Foeger, Meinhard Haltmayer, Andreas Ritsch, Josef R. Patsch,
Hepatic lipase plays a key role in the metabolism of pro-atherogenic and anti-atherogenic lipoproteins affecting their plasma level as well as their physico-chemical properties. We hypothesized single nucleotide polymorphisms in the promoter region of the hepatic lipase gene to be associated with an increased risk for peripheral arterial disease (PAD).A total of 241 patients with PAD and 241 controls matched for sex and age (+/-2 years) were genotyped cross-sectionally for the --250 single nucleotide polymorphism ...
Tópico(s): Liver Disease Diagnosis and Treatment
2005 - Wiley | Journal of Internal Medicine
Holger Ulmer, Felix Streichert, Andreas Zell,
In many engineering optimization problems the number of fitness function evaluations is limited by time and cost. These problems pose a special challenge to the field of evolutionary computation, since existing evolutionary methods require a very large number of problem function evaluations. One innovative way to address this challenge is the application of approximation models as a surrogate of the real fitness function. Thereby two major points have to be considered. The selection of an appropriate ...
Tópico(s): Metaheuristic Optimization Algorithms Research
2005 - Springer Nature | Studies in fuzziness and soft computing