Sandro Finardi, Paola Radice, Angelo Cecinato, Claudio Gariazzo, Monica Gherardi, Paola Romagnoli,
Abstract An extensive monitoring campaign was conducted between November 2011 and July 2012 at schools, homes, offices and Regional air quality network stations in Rome, within the LIFE+ EXPAH Project. This study allowed to improve the knowledge of actual concentrations and percent composition of Polycyclic Aromatic Hydrocarbons (PAHs) over the city area. High concentrations of all PAH congeners were observed during winter colder periods, e.g. benzo[a]pyrene weekly average concentration reached 3. ...
Tópico(s): Atmospheric chemistry and aerosols
2015 - Elsevier BV | Urban Climate
Gabriele Centi, G. Cerrato, Sergio D'Angelo, Ugo Finardi, Elio Giamello, C. Morterra, Siglinda Perathoner,
Copper-on-zirconia catalysts prepared by a sol-gel technique were found to have an activity in the decomposition of N2O comparable to that of Cu-ZSM-5, but a higher stability at high N2O concentrations. Zirconia promotes the activity of supported copper species and plays a catalytic role itself, but the tetragonal crystalline form of zirconia is more effective in the promotion than the monoclinic form. Characterization of the samples by ESR, IR (CO chemisorption) and oxygen thermodesorption suggests ...
Tópico(s): Catalysis and Hydrodesulfurization Studies
1996 - Elsevier BV | Catalysis Today
Annamaria Nigro, Annamaria Finardi, Marzia M. Ferraro, D. Manno, Angelo Quattrini, Roberto Furlan, Alessandro Romano,
Abstract Microvesicles (MVs) are large extracellular vesicles differing in size, cargo and composition that share a common mechanism of release from the cells through the direct outward budding of the plasma membrane. They are involved in a variety of physiological and pathological conditions and represent promising biomarkers for diseases. MV heterogeneity together with the lack of specific markers had strongly hampered the development of effective methods for MV isolation and differential centrifugation ...
Tópico(s): RNA Interference and Gene Delivery
2021 - Nature Portfolio | Scientific Reports
Andrés J.M. Ferreri, Teresa Calimeri, Paolo Lopedote, Ilaria Francaviglia, Rita Daverio, Chiara Iacona, Cristina Belloni, Sara Steffanoni, Alessandro Gulino, Elena Anghileri, Angelo Diffidenti, Annamaria Finardi, Filippo Gagliardi, Nicoletta Anzalone, Alessandro Nonis, Roberto Furlan, Daniela De Lorenzo, Maria Rosa Terreni, Vittorio Martinelli, Marianna Sassone, Marco Foppoli, Piera Angelillo, Elena Guggiari, Andrea Falini, Pietro Mortini, Massimo Filippi, Vittoria Tarantino, Marica Eoli, Fabio Ciceri, Claudio Doglioni, Claudio Tripodo, Massimo Locatelli, Maria Giulia Cangi, Maurilio Ponzoni,
Reliable biomarkers are needed to avoid diagnostic delay and its devastating effects in patients with primary central nervous system (CNS) lymphoma (PCNSL). We analysed the discriminating sensitivity and specificity of myeloid differentiation primary response (88) (MYD88) L265P mutation (mut-MYD88) and interleukin-10 (IL-10) in cerebrospinal fluid (CSF) of both patients with newly diagnosed (n = 36) and relapsed (n = 27) PCNSL and 162 controls (118 CNS disorders and 44 extra-CNS lymphomas). The concordance of ...
Tópico(s): Glioma Diagnosis and Treatment
2021 - Wiley | British Journal of Haematology
Claudio Gariazzo, Camillo Silibello, Sandro Finardi, Paola Radice, Antonio Piersanti, G. Calori, Angelo Cecinato, Cinzia Perrino, Fabio Nussio, Marco Cagnoli, Armando Pelliccioni, Gian Paolo Gobbi, Patrizia Di Filippo,
The aim of this study was to identify areas of potential relevant exposure to pollutants within Rome's urban core. To meet this goal, intensive field campaigns were conducted and simulations were performed, using the flexible air quality regional model (FARM), to study winter and summer pollution episodes. The simulations were performed using a complete emission inventory that included traffic flow model results of the Roman street network to better describe, with respect to the available diffuse ...
Tópico(s): Wind and Air Flow Studies
2007 - Elsevier BV | Atmospheric Environment
Bhishma Tyagi, Vincenzo Magliulo, Sandro Finardi, Daniele Gasbarra, Pantaleone Carlucci, Piero Toscano, Alessandro Zaldei, Angelo Riccio, Giuseppe Calori, A. D’Allura, Beniamino Gioli,
Predictions of boundary layer meteorological parameters with accuracy are essential for achieving good weather and air quality regional forecast. In the present work, we have analyzed seven planetary boundary layer (PBL) parameterization schemes in a Weather Research and Forecasting (WRF) model over the Naples-Caserta region of Southern Italy. WRF model simulations were performed with 1-km horizontal resolution, and the results were compared against data collected by the small aircraft Sky Arrow Environmental ...
Tópico(s): Wind and Air Flow Studies
2018 - Multidisciplinary Digital Publishing Institute | Atmosphere
Roberto Fogari, Angelo Parini, G Finardi,
Tópico(s): Cardiovascular Disease and Adiposity
1983 - Adis, Springer Healthcare | Drugs
Paolo Enrico, Giuseppe Delvecchio, Nunzio Turtulici, Rosario Aronica, Alessandro Pigoni, Letizia Squarcina, Filippo Maria Villa, Cinzia Perlini, Maria Gloria Rossetti, Marcella Bellani, Antonio Lasalvia, Chiara Bonetto, Paolo Scocco, Armando D’Agostino, Stefano Torresani, Massimiliano Imbesi, F. Bellini, Angelo Veronese, Luisella Bocchio‐Chiavetto, Massimo Gennarelli, Matteo Balestrieri, Gualtiero I. Colombo, Annamaria Finardi, Mirella Ruggeri, Roberto Furlan, Paolo Brambilla, Mirella Ruggeri, Maria Elena Bertani, Sarah Bissoli, Chiara Bonetto, Doriana Cristofalo, Katia De Santi, Antonio Lasalvia, Silvia Lunardi, Valentina Negretto, Sara Poli, Sarah Tosato, Maria Grazia Zamboni, Mario Ballarin, Giovanni de Girolamo, Angelo Fioritti, Giovanni Neri, Francesca Pileggi, Paola Rucci, Massimo Gennarelli, Luisella Bocchio‐Chiavetto, Catia Scasselatti, Roberta Zanardini, Paolo Brambilla, Marcella Bellani, Alessandra Bertoldo, Veronica Marinelli, Valentina Negretto, Cinzia Perlini, Gianluca Rambaldelli,
Tópico(s): Stress Responses and Cortisol
2023 - Springer Nature | Molecular Psychiatry
Rebecca De Lorenzo, Nicola Ivan Lorè, Annamaria Finardi, Alessandra Mandelli, Daniela María Cirillo, Cristina Tresoldi, Francesco Benedetti, Fabio Ciceri, Patrizia Rovere‐Querini, Gıancarlo Comı, Massimo Filippi, Angelo A. Manfredi, Roberto Furlan,
Patients infected with SARS-CoV-2 range from asymptomatic, to mild, moderate or severe disease evolution including fatal outcome. Thus, early predictors of clinical outcome are highly needed. We investigated markers of neural tissue damage as a possible early sign of multisystem involvement to assess their clinical prognostic value on survival or transfer to intensive care unit (ICU). We collected blood from 104 patients infected with SARS-CoV-2 the day of admission to the emergency room and measured ...
Tópico(s): Thermal Regulation in Medicine
2021 - Springer Science+Business Media | Journal of Neurology
Claudio Gariazzo, Camillo Silibello, Sandro Finardi, Paola Radice, A. D’Allura, Monica Gherardi, Angelo Cecinato,
The identification and quantification of population exposure of children and elderly people to PAHs in urban areas are the major goals of the EXPAH LIFE+ Project ( www.ispesl.it/expah ). To reach these objectives an integrated approach, based on measurements and modeling techniques, has been set up to preliminarily reconstruct PAHs levels in the Rome metropolitan area. Field campaigns of particulate PAHs and PM2.5 have been performed in different sites and microenvironments from December 2011 to July ...
Tópico(s): Toxic Organic Pollutants Impact
2014 - Springer International Publishing | Springer proceedings in complexity
Chiara Rossi, Andrea Cugurra, Annamaria Finardi, Andrea Bergamaschi, Roberto Furlan, Angelo Quattrini, Gıancarlo Comı, Gianvito Martino, Luca Muzio,
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2014 - Elsevier BV | Journal of Neuroimmunology
Andrés JM Ferreri, Teresa Calimeri, Paolo Lopedote, Ilaria Francaviglia, Rita Daverio, Chiara Iacona, Cristina Belloni, Sara Steffanoni, Elena Anghileri, Angelo Diffidenti, Annamaria Finardi, Filipppo Gagliardi, Nicoletta Anzalone, Alessandro Nonis, Roberto Furlan, Piera Angelillo, Marianna Sassone, Daniela De Lorenzo, Maria Rosa Terreni, Marco Foppoli, Elena Guggiari, Vittoria Tarantino, Marica Eoli, Fabio Ciceri, Claudio Doglioni, Massimo Locatelli, Maurilio Ponzoni, Maria Giulia Cangi,
Introduction: Early diagnosis remains a major concern in pts with primary diffuse large B-cell lymphoma (DLBCL) of the CNS (PCNSL). Diagnostic delay leads to severe neurological impairment due to prolonged exposure of CNS tissues to tumor infiltration, and protracted steroid therapy, which causes immunodepression and infective complications, the main reasons for treatment interruptions. A few molecular markers have been proposed as diagnostic tools, but reliable parameters that can be easily incorporated ...
Tópico(s): Glioma Diagnosis and Treatment
2019 - Elsevier BV | Blood
Giulia Cesaroni, Francesco Forastiere, Chiara Badaloní, Angelo Cecinato, Sandro Finardi, Maria Pia Gatto, Monica Gherardi, Cinzia Perrino, Paola Romagnoli, Camillo Silibello, Massimo Stafoggia, Claudio Gariazzo, EXPAH Study Group,
Background The evidence on the association between long-term exposure to particles with mortality, above all cardiovascular mortality, is well established. Some studies have shown an association with lung cancer incidence. The association between chronic exposure to polycyclic aromatic hydrocarbons and health outcomes is less clear. The objective of the EXPAH project was to estimate population exposure to PM2.5 and PAH, and to investigate their long-term association with mortality and morbidity ...
Tópico(s): Environmental Justice and Health Disparities
2014 - National Institute of Environmental Health Sciences | ISEE Conference Abstracts
Monica Gherardi, Claudio Gariazzo, Maria Pia Gatto, Francesco Forastiere, Angelo Cecinato, Sandro Finardi, Otto Hänninen, Roberto Sozzi,
2011 - Elsevier BV | Toxicology Letters
Annarita Tagliaferri, Angelo Claudio Molinari, Flora Peyvandi, Antonio Coppola, Francesco Demartis, Chiara Biasoli, Alessandra Borchiellini, Dorina Cultrera, Raimondo De Cristofaro, Filomena Daniele, Paola Giordano, Emanuela Marchesini, Maurizio Margaglione, Renato Marino, Berardino Pollio, Paolo Radossi, Cristina Santoro, Rita Santoro, Sergio Siragusa, Gianluca Sottilotta, Alberto Tosetto, Lydia Piscitelli, Maria Rosaria Villa, Ezio Zanon, Adele Finardi, Irene Schiavetti, Daniella Vaccari, Giancarlo Castaman,
Factor IX replacement therapy is used for treatment and prophylaxis of bleeding in haemophilia B. rIX-FP is an extended half-life albumin-fusion protein, which, in clinical studies, has demonstrated prolonged dosing intervals up to 21 days for routine prophylaxis, providing therapeutic benefit.To describe dosing frequency and consumption (primary endpoint), efficacy and safety of rIX-FP treatment during routine clinical practice in Italy.Patients with moderate/severe haemophilia B on prophylaxis ...
Tópico(s): Platelet Disorders and Treatments
2022 - Wiley | Haemophilia
Massimo Stafoggia, Francesco Forastiere, Angelo Cecinato, Giulia Cesaroni, Annunziata Faustini, Sandro Finardi, Maria Pia Gatto, Monica Gherardi, Cinzia Perrino, Paola Romagnoli, Camillo Silibello, Claudio Gariazzo, EXPAH Group,
Background: short-term association between fine particles (PM2.5) and mortality is well established, while evidence on the effects of PM components, e.g. polycyclic aromatic hydrocarbons (PAHs) is less clear. The project EXPAH aimed at estimating population exposure to PM2.5 and PAHs using spatio-temporal modelling, and investigating their short-term association with mortality in Rome, Italy. Methods: PM2.5, PAHs and benzo[a]pyrene (b[a]p) were measured in 18 locations in Rome during two field campaigns ...
Tópico(s): Air Quality Monitoring and Forecasting
2014 - National Institute of Environmental Health Sciences | ISEE Conference Abstracts
Paolo Enrico, Giuseppe Delvecchio, Nunzio Turtulici, Rosario Aronica, Alessandro Pigoni, Letizia Squarcina, Filippo Maria Villa, Cinzia Perlini, Maria Gloria Rossetti, Marcella Bellani, Antonio Lasalvia, Chiara Bonetto, Paolo Scocco, Armando D’Agostino, Stefano Torresani, Massimiliano Imbesi, F. Bellini, Angelo Veronese, Luisella Bocchio‐Chiavetto, Massimo Gennarelli, Matteo Balestrieri, Gualtiero I. Colombo, Annamaria Finardi, Mirella Ruggeri, Roberto Furlan, Paolo Brambilla,
Nowadays, the lack of quantitative criteria to resolve the diagnostic heterogeneity of psychotic onsets limits the development of safer and more effective treatments. Therefore, the hypothesis to integrate multimodal data to uncover biological subtypes of psychosis has risen [1,2]. Here we explored the existence of subgroups of patients affected by first episode psychosis (FEP) with a possible immunopathogenic basis. To do this, we designed a computational model that use unsupervised machine learning ...
Tópico(s): Asthma and respiratory diseases
2023 - Elsevier BV | Journal of Affective Disorders Reports
Rebecca De Lorenzo, Nicola Ivan Lorè, Annamaria Finardi, Alessandra Mandelli, F. Calesella, Mariagrazia Palladini, Daniela María Cirillo, Cristina Tresoldi, Fabio Ciceri, Patrizia Rovere-Querini, Angelo A. Manfredi, Mario Gennaro Mazza, Francesco Benedetti, Roberto Furlan,
Acute coronavirus disease 2019 (COVID-19) is paralleled by a rise in the peripheral levels of neurofilament light chain (NfL), suggesting early nervous system damage. In a cohort of 103 COVID-19 patients, we studied the relationship between the NfL and peripheral inflammatory markers. We found that the NfL levels are significantly predicted by a panel of circulating cytokines/chemokines, including CRP, IL-4, IL-8, IL-9, Eotaxin, and MIP-1ß, which are highly up-regulated during COVID-19 and are associated ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2024 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences