Doreen Newman, Jonathan Northcroft, Kevin Dunn, John Dugdale, Hala Jaber, Stan Fitzgerald, Matthew Wall, Richard Scase, Helena Frith Powell, Barbara Hall, Steve Strid, Paul Lamarra, Fred Redwood, Gail Porter, Sally Brock, Helen Davies, Phill Jupitus, Rajiv Ouseph, Sean Newsom's, Jack Gordon, Rob Hughes, John Peter, Charles Clover, Gideon Garter, Simon Hacker, Amanda Ursell, Hamish Stevenson, Stephen O'Brien, Phil Willis, Jonathan Miller, Katie Samuel, Andrew Longmore, Jane Mulkerrins, Christopher Godwin, Susan d'Arcy, Ramita Navai, Christopher Catherwood, Tim Danton, Kevin Jelley, Merryn, John peter, Frank Whitford, Sheridan Morley, Nicolette Jones, Ferdinand Mount, Nicki Lewis-Smith, William Lewis, P D, David Smith, Tim Richards, Dominle Prince, John Ellott, David Cracknell Political Editor, Nick Pitt, A L, Richard Green, E P, Andrew Sullivan, Clive Davis, Clyde Rathbone, Ateh Damachi, Andrew Porter, Louise Rennison, Simon Schama, Mike Casey, Susan Berger, Simon Wilde, D C, Matthew Wali, Martin James, Tom Walker, Ariel Leve, Fareed Zakaria, Robert Winnett, Dipesh Gadher Transport Correspondent, Irwin Stelzer, Adrian Furnham, Matt Rudd, Nicola Graydon, Peter Wilson, Brian Shearing, Rosie Millard, Michael Cockayne, Lawrence Dallaglio, James Martin, Charles Collingwood, David Dougill, Danielle Rasdell, Emma John, Frank Graham, Judith Baum, Batasha Varma, Robert Fletcher, Paul Flynn, David Hewson, christopher Higgins, Dominic Bates, David Bond, Hugh Canning, Margarette Driscoll, Marcus Jaye, Graham Duffill, Andrew Stone, Edward Porter, Peter Conradi, Hugh Mcllvanny, Victoria Segal, David Cairns, Michael Portillo, Stewart Lee, Peter Kemp, Patricia Nicol, Harry Drew, Sarah Dempster, Andrew Holgate, Dave Pollard, Kevin Jackson, Camillo Fracassini, John Hart, V Lord, Greg Struthers, Joan Smith, Mel Egglenton, John Patterson, Simon Rogerson, Demetrios Matheou, Lydia Slater, Adam Nathan, Robert Simpson, Peter White, Joe Roff, Andrew Porter Deputy Political Editor, Jeremy Guscott, R Thomas, Sam Torrance, Charles Chesshire, Alex Gallagher, Paul Donovan, John McEnroe, Philip Stephens, Pat Cash, Keith Haskell, Vincent Crump, Hugo Rifkind, B Cross, Chris Woodhead, Lucinda Kemeny, Jasper Gerard, Derek Clements, Colin Marsh, Veronica Berlusconi, Michael Woodhead, Paul Driver, Nicholas Hellen, Richard Brooks, Simon Fanshawe, Ian Hawkey, Shelley Von Strunckel, Christopher Morgan, David Leppard, Lisa Grainger, Alicia Wyllie, Dominic Prince, Mark Edwards, David Evans, Rachel Bridge, Susan Clark, Peter Koening, David Miller, David Morgan, Phil Thomas, Dr Julia Matthews, Louise Gannon, Sutton Coldfield, Nick Reed, Jack Tresidder, Rev'd Dr David Gosling, Christina Lamb, Ian Jones, Raymond Keene, Ian Greaves, Douglas Alexander, Rod Liddle, David Cracknell, Cosmo Landesman, Mary Coop, Zoe Brennan, Oliver Peyton, Diana Wright, E A Alexander, Helen Hawkins, Barry Flatman tennis correspondent, Stephen Jones, Dominic O'Connell, James Tweed, George Gregan, Uzi Mahnaimi, Barry Flatman, Louise Armitstead, Stephen Bleach, Adrienne Connors, Michael Wright, Natalie Graham, Catherine Wheatley, Jonathan Edwards, Stephen Duncan, Miranda Seymour, David Walsh, Liat Joshi, Ben Isaacs, Jack Grimston, Gareth Southgate, Robert Ballantyne, Colin McDowell, Sarah Keenlyside, Stephen Armstrong, John Elliott, Burlington Bertie, Sir Clive Woodward Englad head coach, Bethan Cole, Michael Sheridan Far East Correspondent, Eddie Jones, Jonathan Leake Environment Editor, Victoria O'brien, Richard Woods, Roland White, Alton Douglas, Sheryl Garratt, Shane Watson, Chey Garland, Maurice Chittenden, Cindy Duffield, Ronald White, Sophia Neophitou-Apostolou, David Rees, Mark Franchetti, Richard Rae, Dave Owen, Jon Ungoed-Thomas, Ray Hutton, Ria Higgins, M E, Dan Box, Clare Francis, Anthony Green, John Harlow, Chris Haslam, John Waples, Hunter Davies, Jeremy Hart, A A Gill, Matthew Campbell, Margaret French, Mary Braid, Lois Wilson, Stephen Pettitt, Claudia Croft, Jonathan Leake Science Editor, Sally Kinnes, Naomi Caine, Michael Bright, Peter Almond, Brian Doogan, Fred Miller, Ben Dowell, Minette Marrin, Peter Schmeichel, Jeremy Lazell, James Knight, Andrew Frankel, Graham Norwood, Peter McBarron, Lois Rogers Medical Editor, Stephanie Parker, Clifford Bishop, David Budworth, Hugh Pearman, Tom Voyce, Dan Cairns, Julian Bennett, Justin Jones, Susan d' Arcy, Tony Perrottet, Frank Field, David Smith Economics Editor, Penny Perrick, Susannah Price, Simon Trump, Hugh Bradley, Sarah Baxter, Bob Dwyer, David Robertson, Matthew Goodman, India Knight, Kingston Smith, Simon Howard, Nina Goswami, Jason Dawe, Dominic Rushe, Phil Larder England's defence coach, Karen Robinson, Helen Stewart,
... Lawrence of Arabia has become legendary. But Peter O'Toole is still on the B-list when it ...
2004 - Gale Group | Sunday Times HA GDA
... their comments on a draft of the paper. Annette O'Toole provided valuable assistance in the preparation of the ...
Tópico(s): Regional Economics and Spatial Analysis
1974 - Wiley | Journal of Regional Science
Waldemar Januszczak, Zed Nelson, David Budoworth, Ian Gibson, Fintan O'Toole, Sally Brock, V S, Professor Gideon Garter, Teresa Keane, Rev Msgr Arthur Calkins, Gareth Walsh, Emma Parker Bowles, Ferdinand Mount, Sally O'Reilly, Eben Blacks, Neil Wormald, Martin James, Samantha Weinberg, Rosie Millard, Jenni Muir, David Hewson, Hugh Canning, K Bowden, Hilary Clarke, Sarah Dempster, Annette Hedges, Paul Bailey, Maria McerLane, John Humphrys, Sally Jones, Caroline Scott, J clipson, Christopher Morgan, Cathy Galvin, Alicia Wyllie, John O'Dennell, jonathan Miller, Danny O'Brien, Sir Peter Ustinov, Lindsay Duguid, Robbie Hudson, Colin Smith, Uzi Mahnaimi, Michael Wright, Richard Raa, Fiona Terry, Louisa Grey, S Barber, David Mellor, Eva Klein, John Elliott, Maurice Chittenden, Richard Brooks Arts Editor, Adan Nathan, Helen Mound, R D J, Matthew Campbell, Louise Johncox, Aidan Reilly, Nano Magnetics, Nick Fielding, Lina Das, Guy Herbert, David Wassell, Liam Clarke, David Loviband, Peter Schmeichel, Alan Calveni, Graham Norwood, Geraldine Harckett, David Budworth, Roger Perry, Sarah Baxter, Ed Hughes, Danny Danziger, Monsieur Mangetout, Jason Dawe, Jonathan Northcroft, Hala Jaber, Matthew Wall, Lucas Hollweg, N J, Dr Binod Choudhary, Alastair King, Andrew Longmore, R Phakey, Ms Dynamite, Terry Cleaver, Sir Robin Biggam, Richard Green, Stephen Schneider, Andrew Sullivan, Clive Davis, E P, Brian Jones, Tom Otley, Matt Rudd, Fred Kerr, Nick Speed, Andy Preston, Cally Law, David Bond, Alasdair Reid, Victoria Segal, Edward Porter, Michael Saunders, Jeremy Lennard, L O, Nills Pratley, David Eimer, Brenda Hunt, Adam Nathan, Shelley von Strunckel, Mike Laws, Peter Hounam, Zoe Thomas, John Follain, Richard Brooks, David Pollard, Terry Jons, David Leppard, Monica Bridge, Eben Black Chief Political Correspondent, Hugo Barnacle, David Cracknell, Katrina Manson, Andrew Roberts, Dearbhail McDonald, Barry Flatman, M H, Natalie Graham, S D, David Walsh, R Blackmore, Colin McDowell's, Michael Sheridan Far East Correspondent, Ray Hutton, A A Gill, Kara O'Reilly, Denis Walsh, Brian Glanville, Robert MacFarlane, Simon Allen, Nigel Powell, Brian Doogan, John Aizlewood, Anna McDermott, Jonathan Futrell, Huw Beynon, Tom Deveson, Martin Booth, Richard Lewis, John Dugdale, Barbara Hall, Nigel Botherway, Paul Steel, Rob Hughes, John Peter, Maggie Alderson, Mean Fields, Somerset, Jane Mulkerrins, J D, David Gower, Markie Robson-Scott, David Smith, Tim Richards, David Cracknell Political Editor, J M Coetzee, Alan Aitchison, Stephen Grey, Sally Brown, J D Thom, Peter Kilfoyle MP, Tom Walker, Wendy Holden, Steven Dunn, Edward Luttwak, H C, Hugh Mcllvanney, Stewart Lee, Isabel Stirling, Patricia Nicol, John O'Donnell, Dr David O'Regan, Lesley Downer, Sir Richard Branson, Jeremy Guscott, David Walsh Chief Sports Writer, lony Barrell, Tom Conran, Paul Kimmage, Chris Woodhead, Chiae Beeney, James Murphy, Mark Edwards, Susan Clark, Kira Cochrane, Raymond Keene, Pupert Steimer, Hilary Clark, Marie Colvin, Stephen Jones, Louise Armitstead, Nick Cain, Melinda Stevens, June Field, Henry Stewart, Trevor Lewis, Caroline Haydon, Roland White, Danny Roth, Neit Kirk, Richard Rae, Jon Ungoed-Thomas, Huw Richards, Cynthia Ellis, Julie Cracknell, Dominic O'Connell Matthew Goodman, Deborah Scroggins, Niall Ferguson, Dipesh Gadher, John Waples, David Gracknell, Stephen Pettitt, Justin Sparks, Rajiv Radhakrishnan, E B, Bitter Pill, Mark Hodson, Andrew Frankel, Joe Lovejoy, L Bugler, Dan Cairns, David Smith Economics Editor, Anthony Howard, Sandy Gall, Simon Howard, Dominic Rushe, John Ramwell, Sarah Cracknell, Tracey Cox, Fred Redwood, David Brown, Jo Reess, Helen Davies, Brian Parker, Sarah Boxter, Tom Dixon, Frank Ansuis, Kathryn Cooper, William Lewis, Humphrey Carpenter, David Schwartz, Tony Allen-Mills, Simon Wilde, Robert Sandall, Robert Winnett, Irwin Stelzer, Peter Wilson, David Dougill, Rachel Dobson, Dr Manrice Slevin, Nazaneen Rashid, Frank Graham, David Higgins chief executive, Ross Williams, Rob Maul, Jonathon Carr-Brown, Jeremy Clarkson, David Cairns, Louise Taylor, Liz Edwards, Paula Robinson, Alfred Litten, John Thompson, Roger Eglin, Steve Waugh, Lucinda Kemeny, Jasper Gerard, Sarah Mockford, Derek Clements, Michael Woodhead, Paul Driver, Ian Hawkey, Paul Durman, Hugh Jamieson, Jane Nottage, Frank McCourt, Bob Graham, Cosmo Landesman, Gavin Conway, Dominic O'Connell, Christina Lamp, Tony Allen Mills, M J, Jilly Cleaver, Ron Clarke, Katy Luck, John Harlow, John T Morris, Melanie McDonagh, Jonathan Leake Science Editor, Sally Kinnes, David Wickers, Rupert Steiner, Michael John, Paul Stephen Lubicz, Pete Oliver, Stephen Nelson, Matthew Goodman, India Knight, Kingston Smith,
... Adams plans one final political coup, writes Fintan O'Toole Travel The Sunday Times crossword Love you to ...
2003 - Gale Group | Sunday Times HA GDA
Sallie Baxendale, Annette O’Toole,
Many myths are perpetuated and reinforced in the portrayal of fictional characters with epilepsy in films and on television. Common cinematic treatment myths include the necessity for immediate medical intervention in the form of an ambulance crew to stop a seizure and the placing of an object in the seizing person's mouth to prevent the person from choking on her or his tongue. Other misrepresentations include excessive "foaming" at the mouth during a seizure and frequent violence. We conducted ...
Tópico(s): Memory Processes and Influences
2007 - Elsevier BV | Epilepsy & Behavior
Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Hala Jaber, Barbara Hall, Doug Endersby, John Smith, David Barber, N J, Michelene Wandor, Jon Swain, Philip Norman, P Hutchinson, Sally Brock, Rob Hughes, John Peter, V S, Professor Gideon Garter, Chrissy Hey, William Lewis Business Editor, Amanda Ursell, Jonathan Miller, Jeane-Pierre Frankenhuis, Andrew Longmore, Kate Spicer, Katrina Mansion, Christopher Wood, Susan d'Arcy, J D, Peter Beaumont, Gareth Walsh, Frank Whitford, Ray Spiller, Ferdinand Mount, Anthony Lyman-Dixon, Kathryn Cooper, Susan Bell, William Lewis, P D, David Smith, Darren Campbell, Tim Richards, Dominic Utton, Paul Driver, Robert Sabdall, David Cracknell Political Editor, Michael Kilcommons, Neil Wormald, Sir Nigel Crisp Chief Executive, Richard Green, E P, Lynne Truss, Elizabeth Smith, Tony Allen-Mills, Simon Wilde, John O'Brien, Martin James, Ronald Trewartha, Anthony Sattin, Robert Winnett, Charles Nicholl, Tom English, Peter Wilson, Rosie Millard, Lawrence Dallaglio, Neil Wormaid, Rachel Dobson, Peter Wyman, David Dougill, Alan Bergson, Colln Brennan, Rod Wilkinson, Vinny Lee, Philippe Legrain chief economist, C Scully, Anna Bruning, Philip Kingsley, Thrasy Petropoulos, Dumeetha Luthra, Rob Maul, David Hewson, Patrick Campbell, Hugh Canning, Geraldine Hackett Education Correspondent, Nils Pratley, Jeremy Clarkson, Raymond Gubbay, Edward Porter, Peter Conradi, Victoria Segal, Hilary Clarke, Sarah Dempster, C Francis Warren Lancaster, Eben Black, John O'Donnell, K Browning, Shelley von Strunckel, Hugh McllVanney, Karthryn Cooper, Jeremy Guscott, John Sands Chairman of Pubmaster, Alicia Wyillie, Paula Robinson, David Walsh Chief Sports Writer, Annette Walker, L Goring, Roger Eglin, Paul Donovan, Tom Conran, Steve Waugh, Chris Woodhead, Madeleine Channer, Martin Spiro, Lucinda Kemeny, Jasper Gerard, Derek Clements, lrwin Stelzer, Michael Woodhead, John Humphrys, Michael Barrows, Nicholas Hellen, Murray Walker, Richard Brooks, Garth Pearce, David Leppard, Paul Durman, S Rodway, Mark Ludlow, Lisa Grainger, Alicia Wyllie, John Walker, John Mahoney, Mark Edwards, Sarah Gracie, David Pope, Susan Clark, Stephen Amidon, Matthew Sheahan, Zoë Brennan, Christina Lamb, Sean Newsom, Rehan Kularaine, Raymond Keene, William Chadwick, Gareth Huw Davies, David Cracknell, Stanley Stewart, Cosmo Landesman, Robbie Hudson, Jeff Tracy, Karina Mantavia, lan Hawkey, Andrea Maflin, Dr Gill Morgan, Stephen Jones, Dominic O'Connell, Stephen Bleach, Barry Flatman, Nick Cain, Michael Wright, Jenny Pitman, Daniel Dennett, Melinda Stevens, Natalie Graham, Kate Rew, M J, Caroline Donald, S D, Rob Ryan, Keith Wheatley, Jessica Brinton, David Walsh, Brian Ferguson, Jack Grimston, Colin McDowell, Bryan Appleyard, Stephen Armstrong, John Elliott, Colin McDowell's, Mark Anstead, Desmond Kilcoyne, Roger Frost, Bethan Cole, Sheherazade Goldsmith, Cox, Roland White, David Milburn, Maurice Chittenden, Scott Goodrick, Tom Naylor, Robert Mecall, Richard Brooks Arts Editor, Dr John Pitts, Bill Joel, Richard Rae, Mark Franchetti, Ray Hutton, Claudia Croft, Jon Ungoed-Thomas, Alexandra Dawe, Orazio Gualtieri, Naomi Wolf, Michael Sheridan, Deborah Scroggins, Simon Potter, John Harlow, Peter Clarke, Michael Austin, Dipesh Gadher, John Waples, Mike Slay, A A Gill, Ros Dodd, Brian Glanville, Louise Johncox, John Carey, Enda Leahy, Tom Robbins, Mary Braid, Nick Fielding, Lewis Stuart, Jason Mellor, Lauren St John, Jonathan Calvert, Jonathan Leake Science Editor, T L, Ken Yankey, Peter Walker, Long Nails, Justin Sparks, Sally Kinnes, Maria McErlane, Naomi Caine, Nigel Powell, Jeff Lampert Competitive Business Banking Analysis, Hugh McilVanney, David Wickers, Roger Dobson, Brian Doogan, Minette Marrin, John Cornwell, Mark Hodson, Andrew Frankel, Graham Norwood, Joe Lovejoy, Jonathan Futrell, P Coates, Rupert Steiner, M Norwell, David Budworth, T Cawley, Dan Cairns, Paul Stephen Lubicz, Steve Henley, Allica Wyllie, Hugh Pearman, Robert Kagan, David Smith Economics Editor, Marianne Bartram, Sarah Baxter, Patricia Cleveland-Peck, Ruth Bull, Helen Vandevelde, Chris Feetenby, Vernon Coleman, Gerald Kennedy, Professor Carof Black, Matthew Goodman, India Knight, Simon Howard, John Sanderson, Danny Danziger, Mary Dunkin, Jason Dawe, Sabi Phagura, Dominic Rushe, Sian Griffiths, Mansieur Mangetout, Felix Dennis,
... Lotto jackpot Radisson Edwardian Hotels Israeli soldiers die O'Toole's Oscar British film wins Hepatitis scare Fatal ...
2003 - Gale Group | Sunday Times HA GDA
Dominique Flügel, Mara Cercignani, Mark R. Symms, Annette O’Toole, Pamela J. Thompson, Matthias J. Koepp, Jacqueline Foong,
Summary: Purpose: To examine frontotemporal white‐matter integrity in patients with temporal lobe epilepsy (TLE) and interictal psychosis. Method: Patients with TLE and interictal psychosis (IP; n = 20) were compared with age‐matched TLE patients without psychosis (NIP; n = 20). Patients had either no focal lesions or hippocampal sclerosis on conventional MRI. Complete diffusion tensor imaging (DTI) data were available in 18 IP and 20 NIP patients. A region‐of‐interest (ROI) approach was used to determine ...
Tópico(s): Advanced MRI Techniques and Applications
2006 - Wiley | Epilepsia
Dominique Flügel, Annette O’Toole, Pamela J. Thompson, Matthias J. Koepp, Mara Cercignani, Mark R. Symms, Jacqueline Foong,
Tópico(s): Functional Brain Connectivity Studies
2006 - Elsevier BV | Epilepsy Research
Annette F. Muttray, Teagan F. O'Toole, Wendy Morrill, Rebecca J. Van Beneden, Susan A. Baldwin,
The mussel Mytilus trossulus can develop a neoplasia of the haemolymph, which occurs with high frequency (up to 40%) in nature. Associated with this disease are pro-apoptotic tumor-suppressor protein p53 isoforms, which are highly conserved between molluscs and vertebrates. The vertebrate wildtype p53 protein is maintained at low levels by the MDM2 protein in non-stressed cells to prevent undesired apoptosis. Identification of a putative invertebrate MDM-like homolog suggests early evolution of this ...
Tópico(s): Cancer Research and Treatments
2010 - Elsevier BV | Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
Natasha L. Browne, Nick O. Carragher, Annette O’Toole, John Pimm, Joanne Ryder, Graham R. Thew,
Abstract Online peer support platforms have been shown to provide a supportive space that can enhance social connectedness and personal empowerment. Some studies have analysed forum messages, showing that users describe a range of advantages, and some disadvantages to their use. However, the direct examination of users’ experiences of such platforms is rare and may be particularly informative for enhancing their helpfulness. This study aimed to understand users’ experiences of the Support, Hope ...
Tópico(s): Mental Health Treatment and Access
2022 - Cambridge University Press | The Cognitive Behaviour Therapist
Sandra Reitmeier, Silke Kießling, Thomas Clavel, Markus List, Eduardo L. Almeida, Tarini Shankar Ghosh, Klaus Neuhaus, Harald Grallert, Jakob Linseisen, Thomas Skurk, Beate Brandl, Taylor A. Breuninger, Martina Troll, Wolfgang Rathmann, Birgit Linkohr, Hans Hauner, Matthias Laudes, André Franke, Caroline Le Roy, Jordana T. Bell, Tim D. Spector, Jan Baumbach, Paul W. O’Toole, Annette Peters, Dirk Haller,
Summary Lifestyle, obesity, and the gut microbiome are important risk factors for metabolic disorders. We demonstrate in 1,976 subjects of a German population cohort (KORA) that specific microbiota members show 24-h oscillations in their relative abundance and identified 13 taxa with disrupted rhythmicity in type 2 diabetes (T2D). Cross-validated prediction models based on this signature similarly classified T2D. In an independent cohort (FoCus), disruption of microbial oscillation and the model for T2D classification ...
Tópico(s): Tryptophan and brain disorders
2020 - Cell Press | Cell Host & Microbe
... in a recent survey by Sallie Baxendale and Annette O'Toole at University College London, London, UK. 1 Baxendale ...
Tópico(s): Epilepsy research and treatment
2007 - Elsevier BV | The Lancet
Sandra Reitmeier, Silke Kießling, Thomas Clavel, Markus List, Eduardo L. Almeida, Tarini Shankar Ghosh, Klaus Neuhaus, Harald Grallert, Martina Troll, Wolfgang Rathmann, Birgit Linkohr, Andre Franke, Caroline Le Roy, Jordana T. Bell, Timothy D. Spector, Jan Baumbach, Paul W. O’Toole, Annette Peters, Dirk Haller,
Lifestyle, obesity and the gut microbiome are among the most important risk factors for the development of metabolic disorders. We demonstrate in 1,976 subjects of a prospective population cohort (KORA) that specific gut microbiota members show 24-hour oscillations in their relative abundance and identified 13 taxa with disrupted rhythmicity in T2D. Cross-validated prediction models based on this signature classified T2D with an AUC of 73%. BMI as independent factor improved classification of T2D. ...
Tópico(s): Machine Learning in Healthcare
2020 - RELX Group (Netherlands) | SSRN Electronic Journal
Kirsten van Gysen, Andrew Kneebone, Andrew Le, Kenny Wu, Annette Haworth, Regina Bromley, George Hruby, James O’Toole, Jeremy Booth, Chris Brown, Maria Pearse, Mark Sidhom, Kirsty Wiltshire, Colin Tang, Thomas Eade,
Poor quality radiotherapy can detrimentally affect outcomes in clinical trials. Our purpose was to explore the potential of knowledge-based planning (KBP) for quality assurance (QA) in clinical trials.Using 30 in-house post-prostatectomy radiation treatment (PPRT) plans, an iterative KBP model was created according to the multicentre clinical trial protocol, delivering 64 Gy in 32 fractions. KBP was used to replan 137 plans. The KB (knowledge based) plans were evaluated for their ability to fulfil the ...
Tópico(s): Statistical Methods in Clinical Trials
2022 - Elsevier BV | Physics and Imaging in Radiation Oncology
Obbina Abani, Ali Abbas, Fatima Abbas, Joshua Abbas, Kasim Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Alison Abbott, Nabeel Abdallah, Ammar Abdelaziz, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, A Abdul, Basir Abdul, Siddiqui Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Lynn Abel, Katrina Abernethy, Movin Abeywickrema, C Abhinaya, Affyarsyah Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, Heba Aboelela, Hani Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, Mona Abouzaid, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Rebecca Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yousuf Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Prince Acheampong, Sarah Acheampong, Janet Acheson, S Achieng, Andrés Acosta, Rebecca Acquah, Catherine Acton, Jacqueline Adabie-Ankrah, Paul Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Marta Adamczyk, Carol Adams, Charlotte Adams, Daniel Adams, Kate Adams, Laura Adams, Nikkita Adams, Richard Adams, Tim Adams, L Adamu-Ikeme, Krishma Adatia, Kirsty Adcock, Afua Addo, Oluwatobi Adeagbo, Ade Adebiyi, Ogunlana Adedeji, Yewande Adegeye, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Femi W Adeoye, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Adedamola Adeyanju, Joyce Adeyemi, Tenifayo Adeyemo, Binay Adhikari, Rina Adhikary, Adhikarla Aditya, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, L A Aguilar Jimenez, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, M. Ridwan Said Ahmad, Syed A. Ahmad, Afshan Ahmed, Ashar Ahmed, Asim Ahmed, Basheer A R Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Hanad Ahmed, Irshad Ahmed, Khaled Ahmed, Khalil Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rawya Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sana Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Bilal A Mohamud, Sana Ahmed, Sana Ahmer, A Ahonia, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, B Akinbiyi, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Mohammad Akram, Olugbenro Aktinade, U Akudi, Ahmad S A R Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Adegoke Alabi, Narendra Aladangady, Mohamed Alafifi, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Angela Alcala, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ram Maya Ale, Ana Alegria, Alison Alexander, Courtney Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, Rafil Alhameed, Mohammed Al-Hayali, Shams Al‐Hity, Ali Ali, Amanda Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohamed M. Ali, Mohammad Ali, Muhammad Ali, Nayab Ali, Oudai Ali, Ramla Ali, Sakina Ali, Irfan Syed, E Aliberti, J Alin, Abid Alina, A Alipustain, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, A. Alkhudhayri, Moutaz Alkhusheh, Fiona Allan, Nataliya Allan, Alison Allanson, Robert Allcock, Eireann Allen, Jade Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Tania Allen, A Alli, Kathryn Allison, Bethan Allman, Helen K Allsop, Lynne Allsop, David Allsup, Amal Almahroos, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Fadia Alsheikh, Bashar Al‐Sheklly, Sara Altaf, Amanda Alty, Mary Alvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Katharine Ames, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Badshah Amit, Amjad Amjad, Neelma Amjad, Victoria Amosun, Muhammad Amsal, Khaled Amsha, Noelia Martín, Pugh Amy, A Anada, Atul Anand, Samantha Anandappa, Satya D Anantapatnaikuni, Ellen Anderson, Julie Anderson, Laura Anderson, Marina Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson,
BackgroundWe aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, for the treatment of patients admitted to hospital with COVID-19.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised with COVID-19 in the UK. Eligible and consenting patients were randomly allocated (1:1) to either usual standard of care alone (usual care group) or usual care plus ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Joshua Abbas, Kasim Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Alison Abbott, Nabeel Abdallah, Ammar Abdelaziz, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, A Abdul, Basir Abdul, Siddiqui Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Lynn Abel, Katrina Abernethy, Movin Abeywickrema, C Abhinaya, Affyarsyah Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, C Aboah, Heba Aboelela, Hani Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, Mona Abouzaid, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, J. Abrams, Rebecca Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yousuf Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Faustina Acheampong, Prince Acheampong, Sarah Acheampong, Janet Acheson, S Achieng, Andrés Acosta, Rebecca Acquah, Catherine Acton, Jacqueline Adabie-Ankrah, Paul Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Marta Adamczyk, Carol Adams, Charlotte Adams, Daniel Adams, Kate Adams, Laura Adams, Nikkita Adams, Richard Adams, Tim Adams, L Adamu-Ikeme, Krishma Adatia, Kirsty Adcock, L Addai-Boampong, Afua Addo, Oluwatobi Adeagbo, Ade Adebiyi, Ogunlana Adedeji, Yewande Adegeye, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Femi W Adeoye, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Adedamola Adeyanju, Joyce Adeyemi, Tenifayo Adeyemo, Binay Adhikari, Shanti A Adhikari, Rina Adhikary, Adhikarla Aditya, P Adjepong, Gabrielle Adkins, Adnan Adnan, Marguerite Adriaanse, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Iqbal Afridi, P Afrim, Felicia Akua Afriyie, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, L A Aguilar Jimenez, Jacqueline Afrakomah Agyekum, K Agyen, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Afshan Ahmed, Ashar Ahmed, Asim Ahmed, Basheer A R Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Hanad Ahmed, Irshad Ahmed, Khaled Ahmed, Khalil Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rawya Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sana Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Bilal A Mohamud, Sana Ahmed, Sana Ahmer, A Ahonia, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, B Akinbiyi, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Mohammad Akram, Olugbenro Aktinade, U Akudi, Ahmad S A R Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Adegoke Alabi, Narendra Aladangady, Mohamed Alafifi, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Albertus Albertus, Lorraine Albon, Angela Alcala, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ram Maya Ale, Ana Alegria, Alison Alexander, Courtney Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, Rafil Alhameed, Mohammed Al-Hayali, Shams Al‐Hity, Ali Ali, Amanda Ali, Ali Asad, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohamed M. Ali, Mohammad Ali, Muhammad Ali, Nayab Ali, Oudai Ali, Ramla Ali, Sakina Ali, Syed Ahsan Ali, E Aliberti, J Alin, Abid Alina, A Alipustain, A Bachti, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, A. Alkhudhayri, Moutaz Alkhusheh, Fiona Allan, Nataliya Allan, Alison Allanson, Robert Allcock, Eireann Allen, Jade Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Tania Allen, A Alli, Kathryn Allison, Bethan Allman, Helen K Allsop, Lynne Allsop, David Allsup, Amal Almahroos, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Fadia Alsheikh, Bashar Al‐Sheklly, Sara Altaf, Amanda Alty, Mary Alvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Robert Ambrogetti, Chris Ambrose, Amir Ameen, A Amelia Ganefianty, Katharine Ames, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Badshah Amit, Amjad Amjad, Neelma Amjad, J Amoah-Dankwa, Victoria Amosun, Muhammad Amsal,
BackgroundLow-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support (non-invasive mechanical ventilation, invasive mechanical ventilation, or extracorporeal membrane oxygenation). We evaluated the use of a higher dose of corticosteroids in this patient group.MethodsThis randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing multiple possible treatments in patients hospitalised ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, D. Abdo, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Amina Abdulle, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Sara J. Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Lisa C. Adams, Richard Adams, Tim Adams, Kirsty Adcock, Jemaimah Addai, Ade Adebiyi, Ken Adegoke, Vicki Adell, Debo Ademokun, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Dominic Affron, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Penny Agent, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Humayun Ahmad, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Sophia Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Giulia Airoldi, Myriam Aissa, Lindianne Aitken, Bini Ajay, Francis Ajeneye, Abdulakeem Ajibode, Ayesha Ajmi, Tahir Akbar, Naim Akhtar, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olajide Akinwumiju, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Karina Al-Asadi, Kyriaki S. Alatzoglou, Manaf Al-Bayati, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Charlotte Alford, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Hoodo Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sabira Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Allameddine Allameddine, Fiona Allan, Rachel Allan, Alison Allanson, Robert Allcock, B. Allen, Eireann Allen, Jess Allen, Kerry Allen, Laura K. Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Balaal Alyas, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Kenneth Amenyah, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Mariam Ammoun, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Rekha Anand, Samantha Anandappa, Julie Anderson, Kevin L. Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Susan Andrews, Gregory Andrikopoulos, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, George Apostolides, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Emily Arbon, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Sylvia Armstrong‐Fisher, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold,
BackgroundMany patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from across the UK. ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Kirsty Adcock, Jemaimah Addai, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Penny Agent, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, M. Ridwan Said Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Charlotte Alford, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizaedeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Ken Amenyah, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Marie Anne Ledingham, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Deborah Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain,
BackgroundIn this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation ( ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Kirsty Adcock, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Binay Adhikari, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Georgia Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Deborah Athorne,
BackgroundAspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients admitted to hospital with COVID-19.MethodsIn this randomised, controlled, open-label, platform trial, several possible treatments were compared with usual care in patients hospitalised with COVID-19. The trial took place at 177 hospitals in the UK, two hospitals in Indonesia, and two hospitals in Nepal. Eligible and consenting ...
Elsevier BV
Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Omar Abdelaziz, Mohamed S. Attia, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul-Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Krishma Adatia, Kirsty Adcock, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Binay Adhikari, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed A. Ahmad, Asim A. Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Syed Haris Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olugbenro Aktinade, Ahmad S A R Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter Alexander, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Asad Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Fiona Allan, Alison Allanson, Robert Allcock, Eireann Allen, Kerry Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Sara Altaf, Mary Alvarez, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy G. Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Louise Anning, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Aquino, Bianca Araba, Samuel Aransiola, Mariana E. G. de Araújo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Georgia Asher, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Abd-El-Aziz Ashour, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Deborah Athorne, Billie Atkins,
BackgroundCasirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety of casirivimab and imdevimab administered in combination in patients admitted to hospital with COVID-19.MethodsRECOVERY is a randomised, controlled, open-label platform trial comparing several possible treatments with usual care in patients ...
Elsevier BV
Eugenia Abaleke, Mustafa Abbas, Sadia Abbasi, Alfie Abbott, Ashraf Omar Abdelaziz, Sherif Abdelbadiee, Mohamed S. Attia, Basir Abdul, Althaf Abdul Rasheed, Rezan A. Kadir, Abdulfatahi Abdulmumeen, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer UA Abeer Ul Amna, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmad Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Devikumar Acharya, Janet Acheson, Andrés Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Kate Adams, Richard Adams, Tim Adams, Malgorzata Adamus, Kirsty Adcock, Aderonke Adebiyi, Ken Adegoke, Vicki Adell, Aldrin Adeni, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Elizabeth Adeyeye, Gabrielle Adkins, Adnan Adnan, John Aeron‐Thomas, Lynn Afari, Debbie Affleck, Carmel Afnan, Deborah Afolabi, Muhammad Abdur Rahman Afridi, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Judith Agwada-Akeru, Kwame A Agyapong, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Jonathan Ah-Chuen, Mahin Ahmad, Ashar Ahmed, Bilal Ahmed, Forizuddin Ahmed, Iram Ahmed, Irshad Ahmed, Liban Ahmed, Maria C Ahmed, Muhammad S. Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmer, Dhiraj Ail, Adam Ainsley, Mark Ainsworth, Myriam Aissa, Lucy Aitchson, Lindianne Aitken, Bini Ajay, Abdulakeem Ajibode, Ayesha Ajmi, Muhammad Nadeem Akhtar, Nasim Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Umeh Akudo, Asma Al Balushi, Majd Al Dakhola, Narendra Aladangady, Sajid Alam, Abbas Al-Asadi, Kyriaki S. Alatzoglou, Lorraine Albon, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John H. Alexander, Peter DG Alexander, Julyan Al-Fori, Bahij Al-Hakim, Shams Al‐Hity, Ali Ali, Anyat Ali, Fawzia R Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Oudai Ali, Sakina Ali, Syed Ahsan Ali, Abid Alina, Katrin Alizaedeh, Maithem Al-Jibury, Moutaz Alkhusheh, Alison Allanson, Robert Allcock, Eireann Allen, Jonathan P. Allen, Kerry Allen, Louise Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Christine Almadenboyle, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Warkaq Al-Shamkhani, Bashar Al‐Sheklly, Mary Alvarez, Maysaa Alzetani, Susan Amamou, S Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Maria R. Amezaga, Allison Amin, Amina Amin, Kanish Amin, Amjad Amjad, Victoria Amosun, Khaled Amsha, Atul Anand, Samantha Anandappa, Julie Anderson, Laura Anderson, Michelle A. Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Prematie Andreou, Angela Andrews, Jill Andrews, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Anu Varghese, Muhammad Naveed Anwar, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Bianca Araba, Angela Aramburo, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Dhawal Arora, Pardeep Arora, Rishi Arora, Arslam Arter, Ganesh Arunachalam, Rita Arya, Salma Asam, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Helen Ashby, Jan Ashcroft, John Ashcroft, Ayesha Ashfaq, Abdul Ashish, Sally Ashman-Flavell, Ashok Raj, Muhammad Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Harshini Asogan, Julia Asplin, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Deborah Athorne, Christopher Atkins, Stacey Atkins, John Atkinson, Vicki Atkinson, Ahmed Attiq, Paula Aubrey, Suzannah August, Aye CT Aung, Hnin Aung, Kyaw Thu Aung, Nini Aung, Zaw Myo Aung, Emily Austin, Karen Austin, Miriam Avery, Joanne Avis, Cristina Avram, Paula Avram, Gabriel Awadzi, Aszad Aya, Eman Ayaz, Amanda Ayers, Vivek Ayra, Jawwad Azam, Mohammed Azharuddin, Ghazala Aziz, Ashaari Azman Shah, Giada Azzopardi, Hocine Azzoug, Nasaruilla Babajan, Fiyinfoluwa Babatunde, Melvin Babi, Babiker Babiker, Gayna Babington, Matthew Babirecki, Adetona O Babs-Osibodu, Gina Bacon, Jenny Bacon, Bibi Badal, Gurpreet R Badhan, Shreya Badhrinarayanan,
BackgroundAzithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.MethodsIn this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospital with COVID-19 in the UK. The trial is underway at 176 hospitals ...
Elsevier BV
Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi, H Abbass, Anne L. Abbott, Nadine Abdallah, Ashraf Omar Abdelaziz, M Abdelfattah, Bushra Abdelqader, A Abdul, Basir Abdul, S Abdul, Abdul Rasheed, Abdulakeem Ajibode, Rezan A. Kadir, Abdullah Mohammed, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, A Abeer Ul Amna, Laurent Abel, Kathy Abernethy, Movin Abeywickrema, C Abhinaya, Ahmad Farid Abidin, Adebanke Aboaba, Abigail Aboagye-Odei, C Aboah, Heba Aboelela, H Abo-Leyah, K Abouelela, Ahmed Abou-Haggar, Mahmoud Abouibrahim, A Abousamra, M. Abouzaid, Mathew Abraham, Tizzy Abraham, A. Abraheem, J. Abrams, Richard Abrams, HJ Abu, Ahmad Abu-Arafeh, SM Abubacker, Akata Abung, Yousef Abusamra, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Faustina Acheampong, Paul Acheampong, Sarah Acheampong, James Acheson, S Achieng, Andrés Acosta, R Acquah, Cindy Acton, Jacqueline Adabie-Ankrah, Pauline Adair, AS Adam, Fiona Adam, Matthew Adam, Huzaifa Adamali, M Adamczyk, Christopher Adams, David H. Adams, Katie Adams, Lisa C. Adams, Nicholas M. Adams, Richard Adams, Tempestt Adams, L Adamu-Ikeme, Krishma Adatia, Kim G. Adcock, L Addai-Boampong, A. Addo, Oluwafemi Adeagbo, Adewole Adebiyi, O. S. Adedeji, Yewande Adegeye, K Adegoke, Vicki Adell, Sherna Adenwalla, FW Adeoye, OA Adesemoye, EO Adewunmi, A Adeyanju, Joyce Adeyemi, Titilope A. Adeyemo, Bidur Adhikari, SA Adhikari, R Adhikary, A. Aditya, P Adjepong, Gabrielle Adkins, Ahmad Adnan, M Adriaanse, J. Aeron-Thomas, Debbie Affleck, Carmel Afnan, Muhammad Abdur Rahman Afridi, P Afrim, FA Afriyie, ZA Aftab, Agnes Awuah, Mudit Agarwal, PN Agasiya, Rachel Agbeko, C Agbo, Sunil Aggarwal, A Aghababaie, L A Aguilar Jimenez, JA Agyekum, K Agyen, EK Ahadome, S Ahamed Sadiq, MH Ahammed Nazeer, Ahmad Mukhtar, Saad Ahmad, A. Ahmed, BAR Ahmed, Bilal Ahmed, Farhan Ahmed, Helal Uddin Ahmed, Irshad Ahmed, Kawsar Ahmed, L Ahmed, Muhammad S. Ahmed, MC Ahmed, MS Ahmed, Nausheen Ahmed, Nausheen Ahmed, Osama Ahmed, RA Ahmed, Rizwan Ahmed, Rizwan Ahmed, Sanam Ahmed, SG Ahmed, SH Ahmed, R Ahmed Ali, Bilal A Mohamud, Sanam Ahmed, Sana Ahmer, A Ahonia, Clement Aidoo, C Aiken, Dhiraj Ail, Mark Ainsworth, Myriam Aissa, L Aitken, B Ajay, Abdulakeem Ajibode, Ahdi Noomen Ajmi, Nahid Akhtar, Suha Akili, B Akinbiyi, O Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Muhammad Akram, Olugbenro Aktinade, U Akudi, ASAR Al Aaraj, Ali Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al‐Abadi, A Alabi, Narendra Aladangady, Mahmoud Alafifi, AHM Khurshid Alam, Md. Samrat Alam, A Al-Asadi, Kyriaki S. Alatzoglou, Paul Albert, A. Albertus, Lorraine Albon, Antonio Luna, Gemma Alcorn, Stephen Alcorn, Andrés Gómez-Aldana, David Alderdice, Abdullah Aldesouki, Rayan Aldouri, Jonathan Aldridge, N. Aldridge, RM Ale, Ana Alegria, Amit Alexander, Craig J. Alexander, John H. Alexander, PDG Alexander, Julyan Al-Fori, Laith Alghazawi, O Alhabsha, Bahij Al-Hakim, R Alhameed, M Al-Hayali, Shams Al‐Hity, Ala Ali, FR Ali, Johar Ali, Mohammad Ali, MS Ali, Nayab Ali, Omar Hasan Ali, R Ali, Syed Ahsan Ali, E Aliberti, J Alin, Abid Alina, A Alipustain, Bachti Alisjahbana, Fine Aliyuda, Kaveh Alizadeh, Maithem Al-Jibury, S Al-Juboori, Mohammad Ali, A. Alkhudhayri, Moutaz Alkhusheh, Frank N. Allan, Nicholas P. Allan, Alison Allanson, Robert Allcock, Emma Allen, Jason W. Allen, Keeley Allen, Louise Allen, Pamela B. Allen, R Allen, Stephen Allen, Tammy D. Allen, A Alli, Kelly C. Allison, Brent E. Allman, HK Allsop, Lynne Allsop, David Allsup, AFT Almahroos, Hassan Al-Moasseb, M Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Z Al-Saadi, Riyam Al-Sammarraie, Inji Alshaer, Rustam Al‐Shahi Salman, Warkaq Al-Shamkhani, F Alsheikh, Bashar Al‐Sheklly, Sana Altaf, A Alty, Míriam J. Álvarez, Maria Alvarez Corral, Edward Alveyn, Maysaa Alzetani, Susan Amamou, N Amar, S Ambalavanan, Robert Ambrogetti, Christopher S. Ambrose, A Ameen, A Amelia Ganefianty, Katharine Ames, M. R. Amezaga, A Amin, A Amin, Kawa Amin, S Amin, Tarek Tawfik Amin, B Amit, Awais Amjad, Nasser Mohammad Amjad, J Amoah-Dankwa, Amos Amoako-Adusei, Victoria Amosun, M Amsal, Khaled Amsha, John Amuasi, Noelia Martín, Pugh Amy, A Anada, Atul Anand, Samantha Anandappa, SD Anantapatnaikuni, NKN Andari, Élizabeth Anderson, Jennifer Anderson,
BackgroundEmpagliflozin has been proposed as a treatment for COVID-19 on the basis of its anti-inflammatory, metabolic, and haemodynamic effects. The RECOVERY trial aimed to assess its safety and efficacy in patients admitted to hospital with COVID-19.MethodsIn the randomised, controlled, open-label RECOVERY trial, several possible treatments are compared with usual care in patients hospitalised with COVID-19. In this analysis, we assess eligible and consenting adults who were randomly allocated ...
Elsevier BV
Saul N. Faust, Richard Haynes, Christine E. Jones, Natalie Staplin, Elizabeth Whittaker, Thomas Jaki, Ed Juszczak, Enti Spata, Mandy Wan, Alasdair Bamford, Paul Dimitri, Adam Finn, John Furness, Athimalaipet V Ramanan, Chris Gale, Katrina Cathie, Simon B. Drysdale, Jolanta Bernatoniene, Clare Murray, Charles Christoph Roehr, Paul Fleming, Andrew Riordan, Srini Bandi, Deepthi Jyothish, Jennifer Evans, Marieke Emonts, Dominic F. Kelly, Nazima Pathan, Patrick Davies, Rosie Hague, Louisa Pollock, Malcolm G. Semple, Leon Peto, J. Kenneth Baillie, Maya H Buch, Katie Jeffery, Marian Knight, Wei Shen Lim, Alan Montgomery, Aparna Mukherjee, Andrew Mumford, Kathy Rowan, Guy Thwaites, Marion Mafham, Jonathan Emberson, Martin Landray, Peter Horby, Lucy C. Chappell, Jeremy Day, DV Dung, Jeremy Day, NN Quang, Prof Binh, Erlina Burhan, Bachti Alisjahbana, Janak Koirala, S Basnet, Evelyne Kestelyn, Buddha Basnyat, Pradip Gyanwali, RL Hamers, Peter Sandercock, Janet Darbyshire, David L. DeMets, Robert Fowler, David G. Lalloo, Mohammed Munavvar, Ian Roberts, Adilia Warris, Janet Wittes, A Craddock-Bamford, Janet Barton, Ahmet Başoğlu, Rosemary Brown, Wojciech Brudlo, Emmanuelle Denis, Lucy Fletcher, Sarah Howard, Sabrina Musini, K. Taylor, Guanglin Cui, Bob Goodenough, Andy J. King, M Lay, David R. Murray, W. Grant Stevens, Karl Wallendszus, Robert C. Welsh, Charles Crichton, Jane C. Davies, Raph Goldacre, Charlie Harper, F Knight, Miles A. Nunn, Hizni Salih, John J. Welch, Mark Campbell, Guilherme Pessoa-Amorim, Mohamed A. Zayed, Jonathan D. Wiles, GRANT P. BAGLEY, Scott J. Cameron, Sarah Chamberlain, Barbara Farrell, Hannah Freeman, Ann R. Kennedy, Anne Whitehouse, Sara Wilkinson, Caroline Wood, Christina Reith, K Davies, Heather Halls, Lisa Holland, Robert Truell, Kevin C. Wilson, Emma Lingwood, L. Howie, Michael P. Lunn, Penelope Rodgers, John Amuasi, Kathleen Baird, Ting Bao, Buddha Basnyat, Mustapha Bittaye, Joseph Bonney, Umberto D’Alessandro, Meghnath Dhimal, Pradip Gyanwali, RL Hamers, T Huyen, Abubacarr Jagne, Abhilasha Karkey, Evelyne Kestelyn, Oumou Maïga, E Matey, Behzad Nadjm, Jeremy Nel, Suman Pant, Khairunnisa Puspatriani, Mutia Rahardjani, S Raijal, Helen Rees, Atika Rimainar, Charles W.M. Roberts, Anna Rocca, Sailendra Kumar Duwal Shrestha, Effua Usuf, C. Vidaillic, Fitria Wulandari, Amit Alexander, M. R. Amezaga, Charlotte Armah, Asma Asghar, Paula Aubrey, Kerry Barker-Williams, Amanda Barnard, John R. Bartholomew, Dawn Beaumont-Jewell, Simon Beddows, J. Beety, Chris Birch, Peter Boyle, Morwenna Brend, Matthew Brookes, Claire Callens, Danielle Campbell, Helen Campbell, Hugo Ten Cate, Emma S. Chambers, K Chapman, Antoinette B. Coe, Joanne Collins, Sarah Crawshaw, Sandeep R. Das, Anthony De Soyza, Erika Denton, Pamela Dicks, Mary Dolman, Kate Donaldson, Lucy Dowden, Shawn Dowling, Charles G. Drake, Hayley Duckles-Leech, Helen Duffy, Lee Gerdes, Kristen Gibbons, Lorena Almeida Gill, Kimberly Gilmour, Joanne Goodwin, James E. Graham, Christopher Green, Claire Hall, Alistair S. Hall, Kate Hampshire, Jane Hanson, T Harman, Helen Harper, Susan T.L. Harrison, James W. Hicks, Helen Hodgson, Michael Hough, Susan Jackson, Graham Johnson, Jodie Kirk, Nicholas R. Lemoine, Chris Levett, S Lock, Teresa Lockett, M Logan, Kaatje Lomme, Jing‐chao Luo, Nigel A.J. McMillan, Helen Membrey, Nhlanhla Mguni, Jane Minton, H Monaghan, Shawn N. Murphy, Natasha Muzengi, Madiha Naz, Ian Nickson, Miranda Odam, Udeme Ohia, Eleanor OKell, Antonio Oliver, Karen Pearson, Kirsty Pine, Richard J. Pleass, David A. Porter, Linda Porter, Alison Potter, Vanessa Poustie, Steven Pratt, Anna Price, Alicia Priest, Anthony Rodgers, C Rook, Pablo Ryan, S Sam, Phoebe Sharratt, James K. Sheffield, Justine Shenton, K Shirley, Timothy Skinner, Herbert B. Slade, Mihaela Sutu, Judy Taylor, E Thomas, Heather Tinkler, Alison Unsworth, R. Usher, William van’t Hoff, S E Walker, James Walters, E Walton, Jenny Warmington, Emma Wayman, Patricia Williams, John Williamson, Deborah A. Williamson, Fiona Yelnoorkar, Marian Knight, Kenneth Hodson, Sue Pavord, Catherine Williamson, Louise Bowman, Fei Chen, Robert W. Clarke, Michelle Goonasekara, William G. Herrington, P. G. Judge, S Ng, David Preiss, Christina Reith, Emily Sammons, Dandan Zhu, C Arkley, Paul Bowker, Johanna Bruce, Victoria Byrne-Watts, G Chapman, Grahame J. Coleman, Tom Denwood, J.D. Gray, David A Harrison, Nancy Mather, Heather Pinches, A.R. Rees, Stephanie Rees, Gail Turner, Obbina Abani, Amr E. Abbas, Fatima Abbas, Jonathan R. Abbas, Kaja Abbas, Mustafa Abbas, Sadia Abbasi,
BackgroundPaediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS-C) emerged in April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess the effect of intravenous immunoglobulin or corticosteroids compared with usual care on duration of hospital stay for children with PIMS-TS and to compare tocilizumab (anti-IL-6 receptor monoclonal antibody) or anakinra (anti-IL-1 receptor ...
Elsevier BV
Franz–Josef Neumann, Lê Thị Phương Thảo, Anne M. Murray, Emily Callander, Prudence R. Carr, Mark Nelson, Rory Wolfe, Robyn L. Woods, Christopher M. Reid, Raj C. Shah, Anne B. Newman, Jeff D. Williamson, Andrew Tonkin, John J. McNeil, John J. McNeil, Anne M. Murray, Lawrence J. Beilin, Andrew K. Chan, Jamehl Demons, Michael E. Ernst, Sara Espinoza, Matthew P. Goetz, Colin I. Johnston, Brenda Kirpach, Danny Liew, Karen L. Margolis, Frank L. Meyskens, Mark Nelson, Chris Reid, Raj C. Shah, Elsdon Storey, Andrew Tonkin, Rory Wolfe, Robyn L. Woods, John Zalcberg, Mark Nelson, Diane G. Ives, Michael Berk, Michael E. Ernst, Donna J. Brauer, Christine Burns, Trevor Chong, Geoffrey Cloud, Jamehl Demons, Geoffrey A. Donnan, Charles B. Eaton, Paul B. Fitzgerald, Peter Gibbs, Andrew Haydon, Michael Jelinek, Finlay Macrae, Suzanne E. Mahady, Mobin Malik, Karen L. Margolis, Catriona McLean, Anne M. Murray, Anne B. Newman, Luz M. Rodriguez, Suzanne Satterfield, Raj C. Shah, Elsdon Storey, Jeanne Tie, Andrew Tonkin, Gijsberta van Londen, Stéphanie Ward, Jeff D. Williamson, Erica M. Wood, John Zalcberg, Jay P. Mohr, Garnet L. Anderson, Stuart J. Connolly, Larry J. Friedman, JoAnn E. Manson, Mary Sano, Sean J. Morrison, E. Magnus Ohman, John J. McNeil, Robyn L. Woods, Walter P. Abhayaratna, Lawrence J. Beilin, Geoffrey A. Donnan, Peter Gibbs, Colin I. Johnston, Danny Liew, Trevor Lockett, Mark Nelson, Chris Reid, Nigel Stocks, Elsdon Storey, Andrew Tonkin, Rory Wolfe, John Zalcberg, Anne M. Murray, Chris Reid, Walter P. Abhayaratna, Michael E. Ernst, Colin I. Johnston, Beth Lewis, Danny Liew, Karen L. Margolis, John J. McNeil, Mark Nelson, Anne B. Newman, Thomas O. Obisesan, Raj C. Shah, Elsdon Storey, Robyn L. Woods, Chris Reid, Jessica E. Lockery, Michael E. Ernst, Dave Gilbertson, Brenda Kirpach, Raj C. Shah, Rory Wolfe, Robyn L. Woods, Jessica E. Lockery, Taya Collyer, Jason Rigby, Kunnapoj Pruksawongsin, Nino Hay, Rory Wolfe, Joanne Ryan, Kim Jachno, Catherine Smith, ARM Saifuddin Ekram, Madeleine Gardam, Henry Luong, Tim Montgomery, Megan Plate, Laura Rojas, Anna Tominaga, Katrina Wadeson, Suzanne G. Orchard, Sharyn M. Fitzgerald, Sarah W. Hopkins, Jessica E. Lockery, Trisha Nichols, Ruth E. Trevaks, Robyn L. Woods, Brenda Kirpach, Ashley C. Johnson, Anne M. Murray, Molly Prozinski, Ramona Robinson‐O’Brien, Nate Tessum, John F. Aloia, Steve Anton, Jeffery Burns, Gary V. Burton, Jamehl Demons, Charles B. Eaton, Michael E. Ernst, Sara Espinoza, Darron Ferris, Mahalakshmi Honasoge, Daniel S. Hsia, Steven Katzman, Anupama Kottam, Beth Lewis, Karen L. Margolis, Anne M. Murray, Shawna D. Nesbitt, Anne B. Newman, Thomas O. Obisesan, Augusto C. Ochoa, Pricilla Pemu, Kevin Peterson, James Powell, Gregg S. Pressman, William H. Robinson, Susanne Satterfield, Raj C. Shah, Christine Thorburn, Elena Volpi, Jocelyn Wiggins, Jeff D. Williamson, Peter Wilson, Catherine Womack, M. Abdullah, S. Abdul-Ridha, E. Aboud, Alyssa Abraham, Jean Abraham, K. Abraham, M. Abrahams, S. Adad, Cameron Adams, N. Africa, S. Afroze, Deepak Agarwal, C. Agbarakwe, W. Ah Sang, Tomás Ahern, Yousif Ahmad, Zahoor Ahmad, Leaque Ahmed, Amjad Ajam, R. Akhter, Z. Akram, K. Alagarswami, M. Afshar Alam, E. Alavi, L. Aldridge, A. Alethan, Karen P. Alexander, Leigh Alexander, M. Alexopoulos, Beriwan Abdulqadir Ali, Mohammed K. Ali, J. Allan, Christopher T. Allen, Genevera I. Allen, Summer V. Allen, P. Allin, R. Al-Musawy, C. Alpren, I. Al-Tawil, T. Alwyn, P. Amor, Tadar Anam, Garnet L. Anderson, Laura N. Anderson, Nancy Anderson, Peter Anderson, Rob Anderson, H. Anderson-Dalheim, E. Andrada, S. Saint André, Leann Andrews, A. Andric, M. Andric, Jenl Khristen Ang, A. Ansari, AM Arakji, Y. Arambeploa, R. Ark, FP Arnaudon, PM Arndt, T. Aroney, J. Arthurson, T. Arunachalam, N. Asim, I. Aslam, S. Assad, N. Astley, M. Athari, C. Atkins, Michael B. Atkins, M. Aufgang, KCY Aung, G. Aurora, S. Auteri, A. Avergun, A. Awwad, C. Azad, S. Azra, A. Babovic, Mirza Kaif Baig, Jillian Baker, Steven Baker, Thea Baker, N. Bakhilova, A. Baldam, A. Baldassa, C. Baldi, C. Balkwill, Olaitan Johnson Balogun, A. Ban, Pratyush Banerjee, M. Banning, S. Bansal, R. Barkas, Anna Barker, David Barker, Anabelle Barnes, N. Barnes, W. Barnetson, I. Barratt, David A. Barrett, Meagan Barrett, Michelle Barrett, Paul M. Barrett, Tyler W. Barrett, P. Barson, C. Barstad, W. I. Barton, M. Bartram, P. Bartusek, Switzerland Basser, Susan Spear Bassett, Louis Batchelor, D. Batt, A. Batty, Sarit Baum, M.J. Baxter, G. Beaton,
Abstract Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, ...
Springer International Publishing
Niamh Mullins, Jooeun Kang, Adrián I. Campos, Jonathan R. I. Coleman, Alexis C. Edwards, Hanga Galfalvy, Daniel F. Levey, Adriana Lori, Andrey A. Shabalin, Anna Starnawska, Mei-Hsin Su, Hunna J. Watson, Mark J. Adams, Swapnil Awasthi, Michael J. Gandal, Jonathan D. Hafferty, Akitoyo Hishimoto, Minsoo Kim, Satoshi Okazaki, Ikuo Otsuka, Stephan Ripke, Erin B. Ware, Andrew W. Bergen, Wade H. Berrettini, Martin Bohus, Harry Brandt, Xiao Chang, Wei J. Chen, Hsi‐Chung Chen, Steven Crawford, Scott J. Crow, Emily DiBlasi, Philibert Duriez, Fernando Fernández‐Aranda, Manfred M. Fichter, Steven Gallinger, Stephen J. Glatt, Philip Gorwood, Yiran Guo, Hakon Hakonarson, Katherine A. Halmi, Hai‐Gwo Hwu, Sonia Jain, Stéphane Jamain, Susana Jiménez‐Múrcia, Craig Johnson, Allan S. Kaplan, Walter H. Kaye, Pamela K. Keel, James L. Kennedy, Kelly Klump, Dong Li, Shih‐Cheng Liao, Klaus Lieb, Lisa Lilenfeld, Chih‐Min Liu, Pierre J. Magistretti, Christian R. Marshall, James E. Mitchell, Eric T. Monson, Richard M. Myers, Dalila Pinto, Abigail Powers, Nicolás Ramoz, Stefan Roepke, Vsevolod Rozanov, Stephen W. Scherer, Christian Schmahl, Marcus Sokolowski, Michael Strober, Laura M. Thornton, Janet Treasure, Ming T. Tsuang, Stephanie H. Witt, D. Blake Woodside, Zeynep Yılmaz, Lea Zillich, Rolf Adolfsson, Ingrid Agartz, Tracy Air, Martin Alda, Lars Alfredsson, Ole A. Andreassen, Adebayo Anjorin, Vivek Appadurai, María Soler Artigas, Sandra Van der Auwera, M.H. Azevedo, Nicholas Bass, Claiton H.D. Bau, Bernhard T. Baune, Frank Bellivier, Klaus Peter Berger, Joanna M. Biernacka, Tim B. Bigdeli, Elisabeth B. Binder, Michael Boehnke, Marco P. Boks, Rosa Bosch, David Braff, Richard A. Bryant, Monika Budde, Enda M. Byrne, Wiepke Cahn, Miguel Casas, Enrique Castelao, Jorge A. Cervilla, Boris Chaumette, Sven Cichon, Aiden Corvin, Nicholas John Craddock, David W. Craig, Franziska Degenhardt, Srdjan Djurovic, Howard J. Edenberg, Ayman H. Fanous, Jerome C. Foo, Andreas J. Forstner, Mark A. Frye, Janice M. Fullerton, Justine M. Gatt, Pablo V. Gejman, Ina Giegling, Hans J. Grabe, Melissa J. Green, Eugênio H. Grevet, Maria Grigoroiu‐Serbânescu, Blanca Gutiérrez, José Guzmán‐Parra, Steven P. Hamilton, Marian L. Hamshere, Annette M. Hartmann, Joanna Hauser, Stefanie Heilmann‐Heimbach, Per Hoffmann, Marcus Ising, Ian Jones, Lisa Jones, Lina Jönsson, René S. Kahn, John R. Kelsoe, Kenneth S. Kendler, Stefan Kloiber, Karestan C. Koenen, Manolis Kogevinas, Bettina Konte, Marie‐Odile Krebs, Mikael Landén, Jacob Lawrence, Marion Leboyer, Phil H. Lee, Douglas F. Levinson, Calwing Liao, Jolanta Lissowska, Susanne Lucae, Fermín Mayoral, Susan L. McElroy, Patrick J. McGrath, Peter McGuffin, Andrew McQuillin, Sarah E. Medland, Divya Mehta, Ingrid Melle, Yuri Milaneschi, Philip B. Mitchell, Esther Molina, Gunnar Morken, Preben Bo Mortensen, Bertram Müller-Myhsok, Caroline M. Nievergelt, Vishwajit L. Nimgaonkar, Markus M. Nöthen, Michael O’Donovan, Roel A. Ophoff, Michael J. Owen, Carlos N. Pato, Michele T. Pato, Brenda W.J.H. Penninx, Jonathan Pimm, Giorgio Pistis, James B. Potash, Robert A. Power, Martin Preisig, Digby Quested, Josep Antoni Ramos‐Quiroga, Andreas Reif, Marta Ribasés, Vanesa Richarte, Marcella Rietschel, Margarita Rivera, Andrea L. Roberts, Gloria Roberts, Guy A. Rouleau, Diego Luiz Rovaris, Dan Rujescu, Cristina Sánchez‐Mora, Alan R. Sanders, Peter R. Schofield, Thomas G. Schulze, Laura J. Scott, Alessandro Serretti, Jianxin Shi, Stanley I. Shyn, Lea Sirignano, Pamela Sklar, Olav B. Smeland, Jordan W. Smoller, Edmund Sonuga‐Barke, Gianfranco Spalletta, John S. Strauss, Beata Świątkowska, Maciej Trzaskowski, Gustavo Turecki, Laura Vilar‐Ribó, John B. Vincent, Henry Völzke, James Walters, Cynthia Shannon Weickert, Thomas W. Weickert, Myrna M. Weissman, Leanne M. Williams, Naomi R. Wray, Clement C. Zai, Allison E. Ashley‐Koch, Jean C. Beckham, Elizabeth R. Hauser, Michael A. Hauser, Nathan A. Kimbrel, Jennifer H. Lindquist, Benjamin H. McMahon, David W. Oslin, Xuejun Qin, Esben Agerbo, Anders D. Børglum, Gerome Breen, Annette Erlangsen, Tõnu Esko, Joel Gelernter, David M. Hougaard, Ronald C. Kessler, Henry R. Kranzler, Qingqin S. Li, Nicholas G. Martin, Andrew M. McIntosh, Ole Mors, Merete Nordentoft, Catherine M. Olsen, David J. Porteous, Robert J. Ursano, Danuta Wasserman, Thomas Werge, David C. Whiteman, Cynthia M. Bulik, Hilary Coon, Ditte Demontis, Anna R. Docherty, Po‐Hsiu Kuo, Cathryn M. Lewis, J. John Mann, Miguel E. Rentería, Daniel J. Smıth, Eli A. Stahl, Murray B. Stein, Fabian Streit, Virginia L. Willour, Douglas M. Ruderfer, Naomi R. Wray, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M. Byrne, Abdel Abdellaoui, Mark J. Adams, Esben Agerbo, Tracy Air, Till F. M. Andlauer, Silviu‐Alin Bacanu, Marie Bækvad‐Hansen, Aartjan T.F. Beekman, Tim B. Bigdeli, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Jonas Bybjerg‐Grauholm, Na Cai, Enrique Castelao, Jane Christensen, Toni‐Kim Clarke, Jonathan R. I. Coleman, Lucía Colodro‐Conde, Baptiste Couvy‐Duchesne, Nick Craddock, Gregory E. Crawford, Gail Davies, Franziska Degenhardt, Eske M. Derks,
Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders.
Elsevier BV
... doi.org/10.1080/09515089.2022.2058925A. Rice O’Toole, Sue Soan Is the employment of pastoral support ...
Tópico(s): Psychology of Moral and Emotional Judgment
1986 - University of Chicago Press | Ethics
Ehud Bodner, Iulian Iancu, Amiram Sarel, Haim Einat,
... Psychiatrica Scandinavica. Supplementum 377:65–72, 1994Google Scholar13. O'Toole BI, Cantor C: Suicide risk factors among Australian ... 59, No. 3LetterJohn Petrila, J.D., LL.M.Annette Christy, Ph.D.1 March 2008 | Psychiatric Services, ...
Tópico(s): Gun Ownership and Violence Research
2007 - American Psychiatric Association | Psychiatric Services
Anke Hinney, Miriam Kesselmeier, Sigrid Jall, A-L Volckmar, Manuel Föcker, Jochen Antel, Vesna Boraska Perica, C. Franklin, James Floyd, Laura M. Thornton, Laura M. Huckins, Lorraine Southam, N. William Rayner, Ioanna Tachmazidou, Kelly L. Klump, Janet Treasure, Cathryn M. Lewis, Ulrike Schmidt, Federica Tozzi, Kirsty iezebrink, Johannes Hebebrand, Philip Gorwood, Roger A.H. Adan, Martien J. Kas, Angela Favaro, Paolo Santonastaso, Fernando Fernández‐Aranda, Mónica Gratacòs, Filip Rybakowski, Monika Dmitrzak‐Węglarz, Jaakko Kaprio, Anna Keski‐Rahkonen, Anu Raevuori, Eric F. van Furth, M Landt, James I. Hudson, Ted Reichborn‐Kjennerud, Gun Peggy Knudsen, Palmiero Monteleone, Allan S. Kaplan, Andreas Karwautz, Hákon Hákonarson, Wade H. Berrettini, Yiran Guo, Dong Li, Nicholas J. Schork, Gen Komaki, Tetsuya Ando, Hidetoshi Inoko, Tõnu Esko, Krista Fischer, Katrin Männik, Andres Metspalu, Jessica H. Baker, Roger D. Cone, Jennifer Dackor, Janiece E. DeSocio, Christopher Hilliard, Julie K. O’Toole, Jacques Pantel, Jin P. Szatkiewicz, Chrysecolla Taico, Stephanie Zerwas, Sara E. Trace, Oliver S. P. Davis, Sietske G. Helder, Katharina Bühren, Roland Burghardt, Martina de Zwaan, Karin Egberts, Stefan Ehrlich, Beate Herpertz‐Dahlmann, Wolfgang Herzog, Hartmut Imgart, André Scherag, Susann Scherag, Stephan Zipfel, Claudette Boni, Nicolás Ramoz, Audrey Versini, Marek K. Brandys, Unna N. Danner, Carolien de Kove, Judith Hendriks, Bobby P.C. Koeleman, Roel A. Ophoff, Eric Strengman, Annemarie Elburg, Alice Bruson, Maurizio Clementi, Daniela Degortes, Monica Forzan, Elena Tenconi, Elisa Docampo, Geòrgia Escaramí, Susana Jiménez‐Múrcia, Jolanta Lissowska, Andrzej Rajewski, Neonila Szeszenia‐Dąbrowska, Agnieszka Slopien, Joanna Hauser, Leila Karhunen, Ingrid Meulenbelt, P. Eline Slagboom, Alfonso Tortorella, Mario Maj, George Dedoussis, Dimitris Dikeos, Fragiskos Gonidakis, Konstantinos Tziouvas, Άρτεμις Τσίτσικα, Hana Papežová, Lenka Šlachtová, Debora Martaskova, James L. Kennedy, Robert D. Levitan, Zeynep Yılmaz, Julia Huemer, Doris Koubek, Elisabeth Merl, Gudrun Wagner, Paul Lichtenstein, Gerome Breen, Sarah Cohen‐Woods, Anne Farmer, Peter McGuffin, Sven Cichon, Ina Giegling, Stefan Herms, Dan Rujescu, Stefan Schreiber, H‐Erich Wichmann, Christian Dina, Robert Sladek, Giovanni Gambaro, Nicole Soranzo, Antonio Julià, Sara Marsal, Raquel Rabionet, Valérie Gaborieau, Danielle M. Dick, Aarno Palotie, Samuli Ripatti, Elisabeth Widén, Ole A. Andreassen, Thomas Espeseth, Astri J. Lundervold, Ivar Reinvang, Vidar M. Steen, Stéphanie Le Hellard, Morten Mattingsdal, Ιωάννα Ντάλλα, Vladimír Bencko, Lenka Foretová, Vladimír Janout, Marie Navratilova, Steven Gallinger, Dalila Pinto, Stephen W. Scherer, H.N. Aschauer, Laura Carlberg, Alexandra Schosser, Lars Alfredsson, Bo Ding, Lars Klareskog, Leonid Padyukov, Chris Finan, Gursharan Kalsi, Marion Roberts, Darren W. Logan, Leena Peltonen, Graham R. S. Ritchie, Jeff Barrett, Xavier Estivill, Anke Hinney, Patrick F. Sullivan, David Collier, Eleftheria Zeggini, Cynthia M. Bulik, Carl A. Anderson, Jeffrey C. Barrett, James Floyd, C. Franklin, Ralph McGinnis, Nicole Soranzo, Eleftheria Zeggini, Jennifer Sambrook, Jonathan Stephens, Willem H. Ouwehand, Wendy L. McArdle, Susan M. Ring, David P. Strachan, Graeme J.M. Alexander, Cynthia M. Bulik, David Collier, Peter J. Conlon, Anna F. Dominiczak, Audrey Duncanson, Adrian V. S. Hill, Cordelia Langford, Graham M. Lord, Alexander P. Maxwell, Linda Morgan, Leena Peltonen, Richard Sandford, Neil Sheerin, Frederik O Vannberg, Hannah Blackburn, Wei‐Min Chen, Sarah Edkins, Matthew Gillman, Emma Gray, Sarah Hunt, Suna Nengut-Gumuscu, Simon Potter, Stephen S. Rich, Douglas J. Simpkin, Pamela Whittaker, Iris M. Heid, Thomas W. Winkler, Paul I. W. de Bakker, Ute Bültmann, Marcel L. Geleijnse, Pim van der Harst, Gerard H. Koppelman, Judith G.M. Rosmalen, Liesbeth van Rossum, Hauke Smidt, Morris A. Swertz, Ronald P. Stolk, Behrooz Z. Alizadeh, R. de Boer, H. Marike Boezen, Marcel Bruinenberg, L. Franke, Pim van der Harst, Hans L. Hillege, Melanie M. van der Klauw, Gerjan Navis, Johan Ormel, Dirkje S. Postma, Judith G.M. Rosmalen, Joris P. J. Slaets, Harold Snieder, Ronald P. Stolk, Bruce H. R. Wolffenbuttel, Cisca Wijmenga, Jeremy J. Berg, Douglas Blackwood, Harry Campbell, J. Cavanagh, J. M. C. Connell, Michael Connor, Sarah Cunningham‐Burley, Ian J. Deary, Anna F. Dominiczak, P. Ellis, Bridie Fitzpatrick, Ian Ford, Robert E. Gertz, Armin Grau, Gill Haddow, Craig Jackson, Shona M. Kerr, Richard Lindsay, Mark McGilchrist, Dan McIntyre, A Morris, Robert W. Morton, William M. Muir, Graham K. Murray, Nicholette D. Palmer, Jill P. Pell, Ashleigh M. Philp, David J. Porteous, Mary Porteous, R. C. Procter, Stuart H. Ralston, David M. Reid, Robert Sinnott, B. F. Smith, David St Clair, Francis Sullivan, Margaret Sweetland, Janice Ure, G. Watt, Raoul Wolf, Alan F. Wright, Sonja I. Berndt, Stefan Gustafsson, Reedik Mägi, Andrea Ganna, Eleanor Wheeler, Mary F. Feitosa, Anne E. Justice, Keri L. Monda,
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with ...
Springer Nature
Phil H. Lee, Verneri Anttila, Hyejung Won, Yen‐Chen Anne Feng, Jacob Rosenthal, Zhaozhong Zhu, Elliot M. Tucker‐Drob, Michel G. Nivard, Andrew D. Grotzinger, Daniëlle Posthuma, Meg M.-J. Wang, Dongmei Yu, Eli A. Stahl, Raymond K. Walters, Richard Anney, Laramie E. Duncan, Tian Ge, Rolf Adolfsson, Tobias Banaschewski, Síntia Belangero, Edwin H. Cook, Giovanni Coppola, Eske M. Derks, Pieter J. Hoekstra, Jaakko Kaprio, Anna Keski‐Rahkonen, George Kirov, Henry R. Kranzler, Jurjen J. Luykx, Luís Augusto Rohde, Clement C. Zai, Esben Agerbo, María J. Arranz, Philip Asherson, Marie Bækvad‐Hansen, Gísli Baldursson, Mark A. Bellgrove, Richard A. Belliveau, Jan K. Buitelaar, Christie L. Burton, Jonas Bybjerg‐Grauholm, Miguel Casas, Felecia Cerrato, Kimberly Chambert, Tracy Air, Bru Cormand, Jennifer Crosbie, Søren Dalsgaard, Ditte Demontis, Alysa E. Doyle, Ashley Dumont, Josephine Elia, Jakob Grove, Ólafur Ó. Guðmundsson, Jan Haavik, Hákon Hákonarson, Christine Søholm Hansen, Catharina A. Hartman, Ziarih Hawi, Amaia Hervás, David M. Hougaard, Daniel P. Howrigan, Hailiang Huang, Jonna Kuntsi, K. Langley, Klaus‐Peter Lesch, Patrick W. L. Leung, Sandra K. Loo, Joanna Martin, Alicia R. Martin, James J. McGough, Sarah E. Medland, Jennifer L. Moran, Ole Mors, Preben Bo Mortensen, Robert D. Oades, Duncan S. Palmer, Carsten Bøcker Pedersen, Marianne G. Pedersen, Triinu Peters, Timothy Poterba, Jesper Buchhave Poulsen, Josep Antoni Ramos‐Quiroga, Andreas Reif, Marta Ribasés, Aribert Rothenberger, Paula Rovira, Cristina Sánchez‐Mora, F. Kyle Satterstrom, Russell Schachar, María Soler Artigas, Stacy Steinberg, Hreinn Stefánsson, Patrick Turley, G. Bragi Walters, Thomas Werge, Tetyana Zayats, Dan E. Arking, Francesco Bettella, Joseph D. Buxbaum, Jane Christensen, Ryan L. Collins, Hilary Coon, Silvia De Rubeis, Richard Delorme, Dorothy E. Grice, Thomas Hansen, Peter Holmans, Sigrun Hope, Christina M. Hultman, Lambertus Klei, Christine Ladd‐Acosta, Páll Magnússon, Terje Nærland, Mette Nyegaard, Dalila Pinto, Per Qvist, Karola Rehnström, Abraham Reichenberg, Jennifer Reichert, Kathryn Roeder, Guy A. Rouleau, Evald Sæmundsen, Stephan Sanders, Sven Sandin, Beaté St Pourcain, Kāri Stefánsson, James S. Sutcliffe, Michael E. Talkowski, Lauren A. Weiss, A. Jeremy Willsey, Ingrid Agartz, Huda Akil, Diego Albani, Martin Alda, Thomas D. Als, Adebayo Anjorin, Lena Backlund, Nicholas Bass, Michael Bauer, Bernhard T. Baune, Frank Bellivier, Sarah E. Bergen, Wade H. Berrettini, Joanna M. Biernacka, Douglas Blackwood, Erlend Bøen, Monika Budde, William E. Bunney, Margit Burmeister, William Byerley, Enda M. Byrne, Sven Cichon, Toni‐Kim Clarke, Jonathan R. I. Coleman, Nicholas Craddock, David Curtis, Piotr M. Czerski, Anders M. Dale, Nina Dalkner, Udo Dannlowski, Franziska Degenhardt, Arianna Di Florio, Torbjørn Elvsåshagen, Bruno Étain, Sascha B. Fischer, Andreas J. Forstner, Liz Forty, Josef Frank, Mark A. Frye, Janice M. Fullerton, Katrin Gade, Héléna A. Gaspar, Elliot S. Gershon, Michael Gill, Fernando S. Goes, Scott D. Gordon, Katherine Gordon‐Smith, Melissa J. Green, Tiffany A. Greenwood, Maria Grigoroiu‐Serbânescu, José Guzmán‐Parra, Joanna Hauser, Martin Hautzinger, Urs Heilbronner, Stefan Herms, Per Hoffmann, Dominic Holland, Stéphane Jamain, Ian Jones, Lisa Jones, Radhika Kandaswamy, John R. Kelsoe, James L. Kennedy, Oedegaard Ketil Joachim, Sarah Kittel‐Schneider, Manolis Kogevinas, Anna C. Koller, Catharina Lavebratt, Cathryn M. Lewis, Qingqin S. Li, Jolanta Lissowska, Loes M. Olde Loohuis, Susanne Lucae, Anna Maaser, Ulrik Fredrik Malt, Nicholas G. Martin, Lina Martinsson, Susan L. McElroy, Francis J. McMahon, Andrew McQuillin, Ingrid Melle, Andres Metspalu, Vincent Millischer, Philip B. Mitchell, Grant W. Montgomery, Gunnar Morken, Derek W. Morris, Bertram Müller‐Myhsok, Niamh Mullins, R Myers, Caroline M. Nievergelt, Merete Nordentoft, Annelie Nordin Adolfsson, Markus M. Nöthen, Roel A. Ophoff, Michael J. Owen, Sara A. Paciga, Carlos N. Pato, Michele T. Pato, Roy H. Perlis, Amy Perry, James B. Potash, Céline S. Reinbold, Marcella Rietschel, Margarita Rivera, Mary Roberson, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Laura J. Scott, Alessandro Serretti, Engilbert Sigurðsson, Olav B. Smeland, Eystein Stordal, Fabian Streit, Jana Strohmaier, Thorgeir E. Thorgeirsson, Jens Treutlein, Gustavo Turecki, Arne E. Vaaler, Eduard Vieta, John B. Vincent, Yunpeng Wang, Stephanie H. Witt, Peter P. Zandi, Roger A.H. Adan, Lars Alfredsson, Tetsuya Ando, H.N. Aschauer, Jessica H. Baker, Vladimír Bencko, Andrew W. Bergen, Andreas Birgegård, Vesna Boraska Perica, Harry Brandt, Roland Burghardt, Laura Carlberg, Matteo Cassina, Maurizio Clementi, Philippe Courtet, Steven Crawford, Scott J. Crow, James J. Crowley, Unna N. Danner, Oliver S. P. Davis, Daniela Degortes, Janiece E. DeSocio, Danielle M. Dick, Christian Dina, Elisa Docampo, Karin Egberts, Stefan Ehrlich, Thomas Espeseth, Fernando Fernández‐Aranda, Manfred M. Fichter, Lenka Foretová, Monica Forzan, Giovanni Gambaro, Ina Giegling, Fragiskos Gonidakis, Philip Gorwood, Monica Gratacos Mayora, Yiran Guo, Katherine A. Halmi, Konstantinos Hatzikotoulas,
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic ...
Cell Press
Thushan I. de Silva, Guihai Liu, Benjamin B. Lindsey, Danning Dong, Shona C. Moore, Sharon Hsu, Dhruv R. Shah, Dannielle Wellington, Alexander J. Mentzer, Adrienn Angyal, Rebecca Brown, Matthew Parker, Zixi Ying, Xuan Yao, Lance Turtle, Susanna Dunachie, Mala K. Maini, Graham S. Ogg, Julian C. Knight, Yanchun Peng, Sarah L. Rowland-Jones, Tao Dong, David M. Aanensen, Khalil Abudahab, Helen Adams, Alexander Adams, Safiah Afifi, Dinesh Aggarwal, Shazaad S.Y. Ahmad, Louise Aigrain, Adela Alcolea-Medina, Nabil-Fareed Alikhan, Elias Allara, Roberto Amato, Tara Annett, Stephen Aplin, Cristina V. Ariani, Hibo Asad, Amy Ash, Paula Ashfield, Fiona Ashford, Laura Atkinson, Stephen W. Attwood, Cressida Auckland, Alp Aydin, David Baker, Paul Baker, Carlos E. Balcazar, Jonathan Ball, Jeffrey C. Barrett, Magdalena Barrow, Edward Barton, Matthew Bashton, Andrew R. Bassett, Rahul Batra, Chris Baxter, Nadua Bayzid, Charlotte Beaver, Angela H. Beckett, Shaun M. Beckwith, Luke Bedford, Robert Beer, Andrew D. Beggs, Katherine L. Bellis, Louise Berry, Beatrice Bertolusso, Angus Best, Emma Betteridge, David C. Bibby, Kelly Bicknell, Debbie Binns, Alec Birchley, Paul Bird, Chloe Bishop, Rachel Blacow, Victoria Blakey, Beth Blane, Frances Bolt, James Bonfield, Stephen Bonner, David Bonsall, Tim Boswell, Andrew Bosworth, Yann Bourgeois, Olivia Boyd, Declan T. Bradley, Cassie Breen, Catherine Bresner, Judith Breuer, Stephen Bridgett, Iraad F. Bronner, Ellena Brooks, Alice Broos, Julianne R. Brown, Giselda Bucca, Sarah L. Buchan, David Buck, Matthew Bull, Phillipa Burns, Shirelle Burton-Fanning, Timothy Byaruhanga, Matthew Byott, Stephen Campbell, Alessandro M. Carabelli, James S. Cargill, Matthew Carlile, Silvia Carvalho, Anna Casey, Anibolina Castigador, Jana Catalan, Vicki Chalker, Nicola J. Chaloner, Meera Chand, Joseph Chappell, Themoula Charalampous, Wendy Chatterton, Yasmin Chaudhry, Carol Churcher, Gemma Clark, Philip Clarke, Benjamin J. Cogger, Kevin D. Cole, Jennifer Collins, Rachel Colquhoun, Thomas R. Connor, Kate F. Cook, Jason D. Coombes, Sally Corden, Claire Cormie, Nicholas Cortes, Marius Cotic, Seb Cotton, Simon Cottrell, Lindsay Coupland, MacGregor Cox, Alison Cox, Noel Craine, Liam Crawford, Aidan Cross, Matthew Crown, Dorian Crudgington, Nicola Cumley, Tanya Curran, Martin D. Curran, Ana da Silva Filipe, Gavin Dabrera, Alistair C. Darby, Rose K. Davidson, Alisha Davies, Robert M. Davies, Thomas P. Davis, Daniela De Angelis, Elen De Lacy, Leonardo de Oliveira Martins, Johnny Debebe, Rebecca Denton-Smith, Samir Dervisevic, Rebecca Dewar, Jayasree Dey, Joana Dias, Donald Dobie, Matthew J. Dorman, Fatima Downing, Megan Driscoll, Louis du Plessis, Nichola Duckworth, Jillian Durham, Kirstine Eastick, Lisa J. Easton, Richard Eccles, Jonathan Edgeworth, Sue Edwards, Kate El Bouzidi, Sahar Eldirdiri, Nicholas Ellaby, Scott Elliott, Gary Eltringham, Leah Ensell, Michelle J. Erkiert, Marina Escalera Zamudio, Sarah Essex, Johnathan M. Evans, Cariad Evans, William V. Everson, Derek Fairley, Karlie Fallon, Arezou Fanaie, Ben W. Farr, Christopher Fearn, Theresa Feltwell, Lynne Ferguson, Laia Fina, Flavia Flaviani, Vicki M. Fleming, Stephen R. Forrest, Ebenezer Foster-Nyarko, Benjamin H. Foulkes, Luke Foulser, Mireille Fragakis, Dan Frampton, Sarah François, Christophe Fraser, Timothy M. Freeman, Helen Fryer, Marc Fuchs, William Fuller, Kavitha Gajee, Katerina Galai, Abbie Gallagher, Eileen Gallagher, Eileen Gallagher, Marta Gallis, Amy Gaskin, Bree Gatica-Wilcox, Lily Geidelberg, Matthew Gemmell, Iliana Georgana, Ryan P. George, Laura Gifford, Lauren Gilbert, Sophia T. Girgis, Sharon Glaysher, Emily J. Goldstein, Tanya Golubchik, Andrea N. Gomes, Sónia Gonçalves, Ian Goodfellow, Scott Goodwin, Salman Goudarzi, Marina Gourtovaia, Clive Graham, Lee Graham, Paul R. Grant, Luke R. Green, Angie Green, Jane Greenaway, Richard D. Gregory, Martyn F. Guest, Rory Gunson, Ravi Kumar Gupta, Bernardo Gutiérrez, Sam Haldenby, William L. Hamilton, Samantha E. Hansford, Tanzina Haque, Kathryn Harris, Ian Harrison, Ewan M. Harrison, Jennifer Hart, John A. Hartley, William T. Harvey, M J Harvey, Mohammed O. Hassan-Ibrahim, Judith Heaney, Thomas Helmer, John Henderson, Andrew R. Hesketh, Jessica Hey, David Heyburn, Ellen E. Higginson, Verity Hill, Jack D. Hill, Rachel A. Hilson, Ember Hilvers, Matthew T. G. Holden, Amy Hollis, Christopher W. Holmes, Nadine Holmes, Alison Holmes, Richard Hopes, Hailey Hornsby, Myra Hosmillo, Catherine Houlihan, Hannah C. Howson‐Wells, Jonathan Hubb, Hannah Huckson, Warwick Hughes, Joseph Hughes, Margaret Hughes, Stephanie Hutchings, Giles Idle, Chris J. Illingworth, Robert Impey, Dianne Irish-Tavares, Miren Iturriza-Gomara, Rhys Izuagbe, Christopher Jackson, Ben Jackson, Leigh Jackson, Kathryn Jackson, David K. Jackson, Aminu S. Jahun, Victoria James, Keith James, Christopher Jeanes, Aaron R. Jeffries,
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted ...
Cell Press
Melissa A. Munn‐Chernoff, Emma C. Johnson, Yi‐Ling Chou, Jonathan R. I. Coleman, Laura M. Thornton, Raymond K. Walters, Zeynep Yılmaz, Jessica H. Baker, Christopher Hübel, Scott D. Gordon, Sarah E. Medland, Hunna J. Watson, Héléna A. Gaspar, Julien Bryois, Anke Hinney, Virpi Leppä, Manuel Mattheisen, Stephan Ripke, Shuyang Yao, Paola Giusti‐Rodríguez, Ken B. Hanscombe, Roger A.H. Adan, Lars Alfredsson, Tetsuya Ando, Ole A. Andreassen, Wade H. Berrettini, Ilka Boehm, Claudette Boni, Vesna Boraska Perica, Katharina Buehren, Roland Burghardt, Matteo Cassina, Sven Cichon, Maurizio Clementi, Roger D. Cone, Philippe Courtet, Scott J. Crow, James J. Crowley, Unna N. Danner, Oliver S. P. Davis, Martina de Zwaan, George Dedoussis, Daniela Degortes, Janiece E. DeSocio, Danielle M. Dick, Dimitris Dikeos, Christian Dina, Monika Dmitrzak‐Węglarz, Elisa Docampo, Laramie E. Duncan, Karin Egberts, Stefan Ehrlich, Geòrgia Escaramís, Tõnu Esko, Xavier Estivill, Anne Farmer, Angela Favaro, Fernando Fernández‐Aranda, Manfred M. Fichter, Krista Fischer, Manuel Föcker, Lenka Foretová, Andreas J. Forstner, Monica Forzan, Christopher S. Franklin, Steven Gallinger, Ina Giegling, Johanna Giuranna, Fragiskos Gonidakis, Philip Gorwood, Monica Gratacos Mayora, Sébastien Guillaume, Yiran Guo, Hákon Hákonarson, Konstantinos Hatzikotoulas, Joanna Hauser, Johannes Hebebrand, Sietske G. Helder, Stefan Herms, Beate Herpertz‐Dahlmann, Wolfgang Herzog, Laura M. Huckins, James I. Hudson, Hartmut Imgart, Hidetoshi Inoko, Vladimír Janout, Susana Jiménez‐Múrcia, Antonio Julià, Gursharan Kalsi, Deborah Kaminská, Leila Karhunen, Andreas Karwautz, Martien J. Kas, James L. Kennedy, Anna Keski‐Rahkonen, Kirsty Kiezebrink, Youl‐Ri Kim, Kelly L. Klump, Gun Peggy Knudsen, Maria C. La Via, Stéphanie Le Hellard, Robert D. Levitan, Dong Li, Lisa Lilenfeld, Bochao Lin, Jolanta Lissowska, Jurjen J. Luykx, Pierre J. Magistretti, Mario Maj, Katrin Männik, Sara Marsal, Christian R. Marshall, Morten Mattingsdal, Sara McDevitt, Peter McGuffin, Andres Metspalu, Ingrid Meulenbelt, Nadia Micali, Karen S. Mitchell, Alessio Maria Monteleone, Palmiero Monteleone, Benedetta Nacmias, Marie Navratilova, Ιωάννα Ντάλλα, Julie K. O’Toole, Roel A. Ophoff, Leonid Padyukov, Aarno Palotie, Jacques Pantel, Hana Papežová, Dalila Pinto, Raquel Rabionet, Anu Raevuori, Nicolás Ramoz, Ted Reichborn‐Kjennerud, Valdo Ricca, Samuli Ripatti, Franziska Ritschel, Marion Roberts, Alessandro Rotondo, Dan Rujescu, Filip Rybakowski, Paolo Santonastaso, André Scherag, Stephen W. Scherer, Ulrike Schmidt, Nicholas J. Schork, Alexandra Schosser, Jochen Seitz, Lenka Šlachtová, P. Eline Slagboom, M Landt, Agnieszka Slopien, Sandro Sorbi, Beata Świątkowska, Jin P. Szatkiewicz, Ioanna Tachmazidou, Elena Tenconi, Alfonso Tortorella, Federica Tozzi, Janet Treasure, Άρτεμις Τσίτσικα, Marta Tyszkiewicz‐Nwafor, Konstantinos Tziouvas, Annemarie Elburg, Eric F. van Furth, Gudrun Wagner, Esther Walton, Elisabeth Widén, Eleftheria Zeggini, Stephanie Zerwas, Stephan Zipfel, Andrew W. Bergen, Joseph M. Boden, Harry Brandt, Steven Crawford, Katherine A. Halmi, L. John Horwood, Craig Johnson, Allan S. Kaplan, Walter H. Kaye, James E. Mitchell, Catherine M. Olsen, John F. Pearson, Nancy L. Pedersen, Michael Strober, Thomas Werge, David C. Whiteman, D. Blake Woodside, Jakob Grove, Anjali K. Henders, Janne Tidselbak Larsen, Richard Parker, Liselotte Petersen, Jennifer Jordan, Martin A. Kennedy, Andreas Birgegård, Paul Lichtenstein, Claes Norring, Mikael Landén, Preben Bo Mortensen, Renato Polimanti, Jeanette N. McClintick, Amy Adkins, Fazil Alıev, Silviu‐Alin Bacanu, Anthony Batzler, Sarah Bertelsen, Joanna M. Biernacka, Tim B. Bigdeli, Li‐Shiun Chen, Toni‐Kim Clarke, Franziska Degenhardt, Anna R. Docherty, Alexis C. Edwards, Jerome C. Foo, Louis Fox, Josef Frank, Laura M. Hack, Annette M. Hartmann, Sarah M. Hartz, Stefanie Heilmann‐Heimbach, Colin A. Hodgkinson, Per Hoffmann, Jouke‐Jan Hottenga, Bettina Konte, Jari Lahti, Marius Lahti‐Pulkkinen, Dongbing Lai, Lannie Ligthart, Anu Loukola, Brion S. Maher, Hamdi Mbarek, Andrew M. McIntosh, Matthew B. McQueen, Jacquelyn L. Meyers, Yuri Milaneschi, Teemu Palviainen, Roseann E. Peterson, Euijung Ryu, Nancy L. Saccone, Jessica E. Salvatore, Sandra Sanchez‐Roige, Melanie L. Schwandt, Richard Sherva, Fabian Streit, Jana Strohmaier, Nathaniel Thomas, Jen‐Chyong Wang, Bradley T. Webb, Robbee Wedow, Leah Wetherill, Amanda G. Wills, Hang Zhou, Jason D. Boardman, Danfeng Chen, Doo‐Sup Choi, William Copeland, Robert Culverhouse, Norbert Dahmen, Louisa Degenhardt, Benjamin W. Domingue, Mark A. Frye, Wolfgang Gäebel, Caroline Hayward, Marcus Ising, Margaret A. Keyes, Falk Kiefer, Gabriele Koller, John R. Kramer, Samuel Kuperman, Susanne Lucae, Michael T. Lynskey, Wolfgang Maier, Karl Mann, Satu Männistö, Bertram Müller‐Myhsok, Alison D. Murray, John I. Nürnberger, Ulrich W. Preuss, Katri Räikkönen, Maureen Reynolds, Monika Ridinger, Norbert Scherbaum, Marc A. Schuckit, Michael Soyka, Jens Treutlein, Stephanie H. Witt, Norbert Wodarz, Peter Zill, Daniel E. Adkins, Dorret I. Boomsma, Laura J. Bierut, Sandra A. Brown, Kathleen K. Bucholz, E. Jane Costello,
Abstract Eating disorders and substance use disorders frequently co‐occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia nervosa and problem alcohol use (genetic correlation [ r g ], twin‐based = 0.23‐0.53). We estimated the genetic correlation between eating disorder and substance use and disorder phenotypes using data from genome‐wide association studies (GWAS). Four eating disorder phenotypes ( ...
Wiley