Àlex G. Segura, Albert Martínez-Pinteño, Patricia Gassó, Natalia Rodríguez, Miquel Bioque, Manuel J. Cuesta, Javier González‐Peñas, Clemente García‐Rizo, António Lobo, Ana González‐Pinto, Alicia García-Alcón, Alexandra Roldán, Eduard Vieta, Josefina Castro‐Fornieles, Anna Mané, Jerónimo Saíz, Miquel Bernardo, Sergi Mas,
Metabolic syndrome is a health-threatening condition suffered by approximately one third of schizophrenia patients and largely attributed to antipsychotic medication. Previous evidence reports a common genetic background of psychotic and metabolic disorders. In this study, we aimed to assess the role of polygenic risk scores (PRSs) on the progression of the metabolic profile in a first-episode psychosis (FEP) cohort.Of the 231 FEP individuals included in the study, 192-220 participants were included ...
Tópico(s): Diabetes Treatment and Management
2022 - Elsevier BV | Schizophrenia Research
Norma Verdolini, Sílvia Amoretti, Gisela Mezquida, Manuel J. Cuesta, Laura Pina‐Camacho, Clemente García‐Rizo, António Lobo, Ana González‐Pinto, Jessica Merchán‐Naranjo, Iluminada Corripio, Estela Salagre, Immaculada Baeza, Daniel Bergé, Marina Garriga, Miquel Bioque, Catalina Vallespir, Maria Serra‐Navarro, Eduard Vieta, Miquel Bernardo,
The aim of the present study was to evaluate the contribution of family environment styles and psychiatric family history on functioning of patients presenting first-episode psychosis (FEP). Patients with FEP and healthy controls (HC) were assessed at baseline and after 2 years. The Functional Assessment Short Test (FAST) was used to assess functional outcome and the Family Environment Scale (FES) to evaluate family environment. Linear regressions evaluated the effect that family environment exerts ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2021 - Elsevier BV | European Neuropsychopharmacology
Daniel Clemente, Paulo Rosa-Santos, Francisco Taveira-Pinto, Paulo Martins, António Paulo Moreira,
Inspired by observing the motions of vessels at sea, the E-Motions has been proposed as an innovative concept capable of converting wave (and wind) induced roll oscillations on multipurpose offshore floating platforms into electricity. The device can be integrated, theoretically, into any type of offshore floating structure, given its simple 3-component design: floating platform, encasing and sliding Power Take-Off. This latter component can be sheltered from the marine environment by being placed ...
Tópico(s): HVDC Systems and Fault Protection
2020 - Elsevier BV | Energy Conversion and Management
Patricia Gassó, Joan Albert Arnáiz, Sergi Mas, Amàlia Lafuente, Miquel Bioque, Manuel J. Cuesta, Covadonga M. Díaz‐Caneja, Clemente García‐Rizo, António Lobo, Ana González‐Pinto, Mara Parellada, Iluminada Corripio, Eduard Vieta, Josefina Castro‐Fornieles, Anna Mané, Natàlia Rodríguez, Daniel Boloc, Jerónimo Saiz‐Ruiz, Miquel Bernardo,
Aims: Patients with a first episode of psychosis (FEP) often display different metabolic disturbances even independently of drug therapy. However, antipsychotic (AP) treatment, especially with second-generation APs, is strongly linked to weight gain, which increases patients’ risk of developing obesity and other metabolic diseases. There is an important genetic risk component that can contribute to the appearance of these disturbances. The aim of the present study was to evaluate the effect of polymorphisms ...
Tópico(s): Schizophrenia research and treatment
2020 - SAGE Publishing | Journal of Psychopharmacology
Miquel Bioque, María Paz García‐Portilla, Clemente García‐Rizo, Bibiana Cabrera, António Lobo, Ana González‐Pinto, Covadonga M. Díaz‐Caneja, Iluminada Corripio, Eduard Vieta, Josefina Castro‐Fornieles, Julio Bobes, Miguel Gutiérrez‐Fraile, Roberto Rodríguez‐Jiménez, Gisela Mezquida, Adrián LLerena, Jerónimo Saiz‐Ruiz, Miquel Bernardo,
Patients with a first episode of psychosis (FEP) display a broad range of metabolic risk factors related to the development of diverse medical comorbidities. Initial stages of these disorders are essential in understanding the increased vulnerability of developing cardiometabolic disturbances, associated with a reduced life expectancy. This study aimed to evaluate the metabolic profile of a cohort of patients with a FEP and its evolution during a two year follow-up, as well as the factors that influence ...
Tópico(s): Bipolar Disorder and Treatment
2017 - Elsevier BV | Schizophrenia Research
Susana Martin Ortigosa, Pedro Díaz‐Vivancos, María José Clemente‐Moreno, Marta Pintó‐Marijuan, Isabel Fleck, Jon Veramendi, Mireya Santos, José Antonio Hernández, J. M. Torné,
As part of a project aiming to characterize the role of maize plastidial transglutaminase (chlTGZ) in the plant chloroplast, this paper presents results on stress induced by continuous chlTGZ over-expression in transplastomic tobacco leaves. Thylakoid remodelling induced by chlTGZ over-expression in young leaves of tobacco chloroplasts has already been reported (Ioannidis et al. in Biochem Biophys Acta 1787:1215-1222, 2009). In the present work, we determined the induced alterations in the photosynthetic ...
Tópico(s): Plant Stress Responses and Tolerance
2010 - Springer Science+Business Media | Planta
Antonino Tuttolomondo, Domenico Di Raimondo, Giusi Irma Forte, Alessandra Casuccio, Giuseppe Lo Re, Letizia Scola, Rosaria Pecoraro, Antonia Serio, Giuseppe Clemente, Valentina Arnao, Marisa Palmeri, Gabriella Misiano, Domenico Lio, António Pinto, Giuseppe Licata,
The genetic basis of complex diseases like ischemic stroke probably consists of several predisposing risk factors, such as genes involved in inflammation and thrombotic pathways. On this basis the aim of our study was to evaluate the role of SNPs (single nucleotide polymorphisms) of some pro-inflammatory/anti-inflammatory and coagulation/fibrinolytic genes in patients with acute ischemic stroke. The study population consisted of 144 consecutive Caucasian adult patients who were hospitalized in the ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2012 - Elsevier BV | Cytokine
Antonino Tuttolomondo, Rosaria Pecoraro, Domenico Di Raimondo, Valentina Arnao, Giuseppe Clemente, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Giuseppe Licata, António Pinto,
Thrombotic strokes can affect large or small arteries in the brain. Drugs to prevent atherosclerosis complication such as thrombotic strokes, should be drugs able to prevent the accumulation of intravascular fat, reduce vascular proliferation, decrease blood pressure levels with the resulting shear stress, reduce platelet aggregation, and possibly partially or totally reverse carotid plaques. Any of the commonly used antihypertensive drugs lower the incidence of stroke, with larger reductions in ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2014 - Bentham Science Publishers | Current Vascular Pharmacology
António E. Cunha, João J. Clemente, Ricardo A. Gomes, Filipe Pinto, M. Thomaz, S. Miranda, Rosa Marı́a Pinto, Dieter Moosmayer, Peter Donner, Manuel J.T. Carrondo,
Abstract Fibronectin splice variant ED B (extracellular domain B) is a promising marker for angiogenesis in growing solid tumors. Currently, recombinant antibodies against ED B are being investigated concerning their potential use, for either therapeutic or diagnostic purposes. Single‐chain antibody fragments directed against the ED B can be efficiently expressed in Pichia pastoris ; thus, a recombinant strain of the methylotropic yeast P. pastoris was used for this work. Three different forms of scFv ...
Tópico(s): Cell Adhesion Molecules Research
2004 - Wiley | Biotechnology and Bioengineering
Antonino Tuttolomondo, Domenico Di Raimondo, Rosaria Pecoraro, Alessandra Casuccio, Danilo Di Bona, Anna Aiello, Giulia Accardi, Valentina Arnao, Giuseppe Clemente, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Calogero Caruso, Rosario Squatrito, António Pinto,
In humans, a major component of natural killer (NK) and T cell target recognition depends on the surveillance of human leukocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs). To implement the knowledge about the immunological genetic background of acute ischemic stroke susceptibility in relation to the frequency of the KIR genes and HLA alleles. Subjects with acute ischemic stroke and subjects without stroke were genotyped for the presence of KIR genes and of the three ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2019 - BioMed Central | Journal of Neuroinflammation
Carmine Pinto, Maria Angela Bella, Ettore Capoluongo, Paola Carrera, Claudio Clemente, Nicoletta Colombo, Laura Cortesi, Gaetano De Rosa, Francesca Fenizia, Maurizio Genuardi, Stefania Gori, Valentina Guarneri, Antonio Marchetti, Paolo Marchetti, Nicola Normanno, Barbara Pasini, Sandro Pignata, Paolo Radice, Enrico Ricevuto, Antonio Russo, Pierosandro Tagliaferri, Pierfrancesco Tassone, Mauro Truini, Liliana Varesco,
... care and treatment pathways of ovarian cancer patientsCarmine Pinto, Maria Angela Bella, Ettore Capoluongo, Paola Carrera, Claudio Clemente, Nicoletta Colombo, Laura Cortesi, Gaetano De Rosa, Francesca Fenizia, Maurizio Genuardi, Stefania Gori, Valentina Guarneri, Antonio Marchetti, Paolo Marchetti, Nicola Normanno, Barbara Pasini, Sandro Pignata, Paolo Radice, Enrico Ricevuto, Antonio Russo, Pierosandro Tagliaferri, Pierfrancesco Tassone, Mauro Truini & Liliana VarescoCarmine Pinto*Author for correspondence: E-mail Address: pinto.carmine@ ...
Tópico(s): DNA Repair Mechanisms
2016 - Future Medicine | Future Oncology
Sílvia Amoretti, Norma Verdolini, Cristina Varo, Gisela Mezquida, Ana M. Sánchez-Torres, Eduard Vieta, Clemente García‐Rizo, António Lobo, Ana González‐Pinto, Renzo Abregú-Crespo, Iluminada Corripio, Maria Serra‐Navarro, Elena de la Serna, Anna Mané, Josep Antoni Ramos‐Quiroga, Marta Ribasés, Manuel J. Cuesta, Miquel Bernardo,
Cognitive reserve (CR) is a protective factor against cognitive and functional impairment in first-episode psychosis (FEP). The aim of this study was to evaluate the differences in clinical presentation according to the use of cannabis (cannabis users vs non-users) among patients presenting a FEP (non-affective vs affective psychosis), to investigate the impact of CR and cannabis use on several outcomes and to explore the potentially mediatory role played by CR in the relationship between cognitive ...
Tópico(s): Bipolar Disorder and Treatment
2022 - Elsevier BV | Journal of Affective Disorders
Nicola Normanno, Carmine Pinto, Gianluigi Taddei, Marcello Gambacorta, Franca Castiglione, Massimo Barberis, Claudio Clemente, Antonio Marchetti,
IntroductionThe Italian Association of Medical Oncology (AIOM) and the Italian Society of Pathology and Cytology organized an external quality assessment (EQA) scheme for EGFR mutation testing in non–small-cell lung cancer.MethodsTen specimens, including three small biopsies with known epidermal growth factor receptor (EGFR) mutation status, were validated in three referral laboratories and provided to 47 participating centers. The participants were requested to perform mutational analysis, using their ...
Tópico(s): Colorectal Cancer Treatments and Studies
2013 - Elsevier BV | Journal of Thoracic Oncology
R. Clemente, Márcio Gonçalves Pinto, Roberto M. Nishida, João Antônio Filho,
Tópico(s): Collaboration in agile enterprises
2003 - | SAE technical papers on CD-ROM/SAE technical paper series
Antonino Tuttolomondo, Rosaria Pecoraro, Alessandra Casuccio, Domenico Di Raimondo, Carmelo Buttà, Giuseppe Clemente, Vittoriano Della Corte, Giuliana Guggino, Valentina Arnao, Carlo Maida, Irene Simonetta, Rosario Maugeri, Rosario Squatrito, António Pinto,
CD4+ CD28− T cells also called CD28 null cells have been reported as increased in the clinical setting of acute coronary syndrome. Only 2 studies previously analyzed peripheral frequency of CD28 null cells in subjects with acute ischemic stroke but, to our knowledge, peripheral frequency of CD28 null cells in each TOAST subtype of ischemic stroke has never been evaluated. We hypothesized that CD4+ cells and, in particular, the CD28 null cell subset could show a different degree of peripheral percentage ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2015 - Wolters Kluwer | Medicine
Produção Nacional
Revisado por pares
Daniel Clemente de Moraes, Karina Martins Cardoso, Levy Tenório Sousa Domingos, Maria do Carmo F. R. Pinto, Robson Q. Monteiro, Antônio Ferreira‐Pereira,
The aim of this study was to evaluate the ability of lapachones in disrupting the fungal multidrug resistance (MDR) phenotype, using a model of study which an azole-resistant Saccharomyces cerevisiae mutant strain that overexpresses the ATP-binding cassette (ABC) transporter Pdr5p. The evaluation of the antifungal activity of lapachones and their possible synergism with fluconazole against the mutant S. cerevisiae strain was performed through broth microdilution and spot assays. Reactive oxygen species ( ...
Tópico(s): Synthesis and Biological Evaluation
2020 - Springer Nature | Brazilian Journal of Microbiology
... nessas vilas. Através do estudo de caso de Antônio Clemente Pinto podemos identificar como a classe senhorial da região ...
Tópico(s): Colonialism, slavery, and trade
2017 - UNIVERSIDADE FEDERAL DE MATO GROSSO | Territórios e Fronteiras
Rute Castro, Lígia S. Nobre, Rute P. Eleutério, M. Thomaz, António Pires, Sandra Monteiro, Sónia Mendes, Ricardo A. Gomes, João J. Clemente, Marcos F. Q. Sousa, Filipe Pinto, Ana Carina Silva, Micael C. Freitas, Ana R. Lemos, Onome Akpogheneta, Lindsay Kosack, Marie‐Louise Bergman, Nádia Duarte, Paula Matoso, Júlia Costa, Tiago M. Bandeiras, Patrícia Gomes‐Alves, Carlos Penha‐Gonçalves, Jocelyne Demengeot, Paula M. Alves,
Serological assays are valuable tools to study SARS-CoV-2 spread and, importantly, to identify individuals that were already infected and would be potentially immune to a virus reinfection. SARS-CoV-2 Spike protein and its receptor binding domain (RBD) are the antigens with higher potential to develop SARS-CoV-2 serological assays. Moreover, structural studies of these antigens are key to understand the molecular basis for Spike interaction with angiotensin converting enzyme 2 receptor, hopefully ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Wiley | Biotechnology and Bioengineering
Antonino Tuttolomondo, Alessandra Casuccio, Carmelo Buttà, Rosaria Pecoraro, Domenico Di Raimondo, Vittoriano Della Corte, Valentina Arnao, Giuseppe Clemente, Carlo Maida, Irene Simonetta, Giuseppe Miceli, Benedetto Lucifora, Anna Cirrincione, Danilo Di Bona, Francesca Corpora, Rosario Maugeri, Domenico Gerardo Iacopino, António Pinto,
Adherence to a Mediterranean Diet appears to reduce the risk of cardiovascular disease, cancer, Alzheimer's disease, and Parkinson's disease, as well as the risk of death due to cardiovascular disease. No study has addressed the association between diagnostic subtype of stroke and its severity and adherence to a Mediterranean Diet in subjects with acute ischemic stroke.To evaluate the association between Mediterranean Diet adherence, TOAST subtype, and stroke severity by means of a retrospective ...
Tópico(s): Dye analysis and toxicity
2015 - Elsevier BV | Atherosclerosis
Marco Gallo, Gennaro Clemente, Domenico Corsi, M. Michelini, C Suraci, Daniele Farci, Maria Chantal Ponziani, Riccardo Candido, Antonio Russo, Nicoletta Musacchio, Carmine Pinto, Domenico Mannino, Stefania Gori,
Abstract Diabetes and cancer frequently coexist in the same subject, often with relevant clinical effects on the management and prognosis of the comorbid patient. The existing guidelines, however, do not appropriately address many clinical issues in this setting. Although collaboration between diabetologists and oncologists should play an important role in achieving appropriate levels of care, close coordination or agreement between these specialists is seldom offered. There is an urgent need for greater ...
Tópico(s): Gastric Cancer Management and Outcomes
2019 - Elsevier BV | Diabetes Research and Clinical Practice
Inmaculada Baeza, Elena de la Serna, Sílvia Amoretti, Manuel J. Cuesta, Covadonga M. Díaz‐Caneja, Gisela Mezquida, António Lobo, Ana González‐Pinto, Iluminada Corripio, Eduard Vieta, Olga Puig, Teresa Legido, Miquel Bioque, Clemente García‐Rizo, Miquel Bernardo, Josefina Castro‐Fornieles,
Most research on first-episode psychosis has focused on adults. This study aimed to explore differences in early-life characteristics of patients with early-onset versus those with adult-onset psychotic disorders and identify predictors of earlier onset.
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2021 - Physicians Postgraduate Press, Inc. | The Journal of Clinical Psychiatry
Meritxell Ventura‐Cots, Josepmaría Argemí, Patricia D. Jones, Carolin Lackner, Mohamed El Hag, Juan G. Abraldeṣ, Edilmar Alvarado, Ana Clemente, Samhita Ravi, António Alves, Mohamed Alboraie, José Altamirano, Sergio Barace, Francisco Bosques‐Padilla, Robert S. Brown, Juan Caballería, Joaquín Cabezas, Sofia Carvalhana, Helena Cortez‐Pinto, Adília Costa, Delphine Degré, Carlos Fernández‐Carrillo, Nathalie Ganne‐Carrié, Guadalupe García–Tsao, Joan Genescà, John Koskinas, Nicolas Lanthier, Alexandre Louvet, Juan José Lozano, Michael R. Lucey, Steven Masson, Philippe Mathurin, Nahúm Méndez‐Sánchez, Rosa Miquel, Christophe Moreno, Taofic Mounajjed, Gemma Òdena, Won Kim, Pau Sancho‐Bru, R. Warren Sands, Justyna Szafranska, Laurine Verset, Bern Schnabl, Christine Sempoux, Vijay H. Shah, Debbie L. Shawcross, Rudolf Stauber, Beate K. Straub, Elizabeth C. Verna, Dina Tiniakos, Eric Trépo, Vı́ctor Vargas, Càndid Villanueva, John T. Woosley, Marianne Ziol, Sebastian Mueller, Peter Stärkel, Ramón Bataller,
Objective Alcohol-related liver disease (ALD) ranges from never-decompensated ALD (ndALD) to the life-threatening decompensated phenotype, known as alcohol-related hepatitis (AH). A multidimensional study of the clinical, histological and molecular features of these subtypes is lacking. Design Two large cohorts of patients were recruited in an international, observational multicentre study: a retrospective cohort of patients with ndALD (n=110) and a prospective cohort of patients with AH (n=225). Clinical, ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2022 - BMJ | Gut
Cláudia Gomes, Miguel Ângelo Basto Clemente de Oliveira e Magalhães, António Amorim, Cı́ntia Alves, Nádia Pinto, Leonor Gusmão,
It is known that autosomal unlinked markers are unable to distinguish some pedigrees (such as grandparent/grandchild, avuncular and half-siblings). This poses a problem especially in cases of identification in mass disasters, other human remains, or in heritage cases where it is crucial to define kinships. Theoretically, X-short tandem repeats (X-STRs) analysis should allow distinction of some of those pedigrees and so a practical approach was undertaken in order to quantify the informative power ...
Tópico(s): Race, Genetics, and Society
2011 - Elsevier BV | Forensic science international. Genetics supplement series
Antonino Tuttolomondo, Domenico Di Raimondo, Chiara Bellia, Giuseppe Clemente, Rosaria Pecoraro, Carlo Maida, Irene Simonetta, Valerio Vassallo, Danilo Di Bona, Eliana Gulotta, Marcello Ciaccio, António Pinto,
Patients with chronic liver diseases are usually thin as a result of hypermetabolism and malnutrition expressed by reduced levels of leptin and impairment of other adyponectins such as visfatin.We evaluated the metabolic and inflammatory effects of intravenous high-dose furosemide plus hypertonic saline solutions (HSS) compared with repeated paracentesis and a standard oral diuretic schedule, in patients with cirrhosis and refractory ascites.59 consecutive cirrhotic patients with refractory ascites ...
Tópico(s): Optimism, Hope, and Well-being
2016 - Public Library of Science | PLoS ONE
Carlos Robalo Cordeiro, Paula Peixoto Campos, Lina Carvalho, Sérgio Campainha, Susana Clemente, L Figueiredo, José Miguel Jesus, J Marqués, Conceição Souto-Moura, R. Pinto Basto, A. Ribeiro, Margarida Serrado, António Morais,
Idiopathic pulmonary fibrosis is a rare interstitial lung disease included in the Idiopathic Interstitial Pneumonias group. Although several potential risk factors have been described, it is a progressive fibrosing disease of unknown cause affecting mainly adults over 50 years and associated with a poor prognosis, reflected in a median survival of 2–3 years after diagnosis. The concept of a multidisciplinary working group for the diagnosis of idiopathic pulmonary fibrosis is based on the need to ...
Tópico(s): Occupational exposure and asthma
2016 - Elsevier BV | Revista Portuguesa de Pneumologia
Miquel Bioque, Ana Catarina Matias-Martins, Vicent Llorca-Bofí, Gisela Mezquida, Manuel J. Cuesta, Eduard Vieta, Sílvia Amoretti, António Lobo, Ana González‐Pinto, Carmen Moreno, Alexandra Roldán, Anabel Martínez‐Arán, Immaculada Baeza, Daniel Bergé, Clemente García‐Rizo, Sergi Mas, Miquel Bernardo, Santiago Madero, Jairo M. González-Díaz, Álvaro Andreu-Bernabeu, Sandra Recio, Judit Selma, Maria Tonda, Edurne García-Corres, Jéssica Fernández-Sevillano, Concepción De‐la‐Cámara, Pedro Modrego-Pardo, Ma José Escartí, Marta Pérez-Rando, Guillermo Vázquez, Sílvia Cristeto, José Sánchez‐Moreno, Anna Giménez‐Palomo, Josefina Castro‐Fornieles, Elena de la Serna, Fernando Hernández Contreras, Leticia González-Blanco, Pilar A. Sáiz, Miguel Gutiérrez‐Fraile, Arantzazu Zabala, Luis Sánchez-Pastor, Roberto Rodríguez‐Jiménez, Judith Usall, Anna Butjosa, Edith Pomarol‐Clotet, Salvador Sarró, Ángela Ibáñez, Ana M. Sánchez-Torres, Vicent Balanzá‐Martínez,
Abstract Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be helpful to characterize this systemic inflammation state. Study Design This study evaluated the NLR in a cohort of 310 subjects with a first episode of psychosis (FEP) and a matched group of 215 healthy controls, recruited in 16 Spanish centers participating in the PEPs Project. We investigated the NLR measures over ...
Tópico(s): Bipolar Disorder and Treatment
2022 - Oxford University Press | Schizophrenia Bulletin
Clemente García‐Rizo, Bibiana Cabrera, Miquel Bioque, Gisela Mezquida, António Lobo, Ana González‐Pinto, Covadonga M. Díaz‐Caneja, Iluminada Corripio, Eduard Vieta, Inmaculada Baeza, María Paz García‐Portilla, Miguel Gutiérrez‐Fraile, Roberto Rodríguez‐Jiménez, Marina Garriga, Emilio Fernández-Egea, Miquel Bernardo,
First episode of psychosis (FEP) patients display a wide variety of metabolic disturbances at onset, which might underlie these patients' increased morbidity and early mortality. Glycemic abnormalities have been previously related to pharmacological agents; however, recent research highlights the impact of early life events. Birth weight (BW), an indirect marker of the fetal environment, has been related to glucose abnormalities in the general population over time. We aim to evaluate if BW correlates ...
Tópico(s): Diet, Metabolism, and Disease
2022 - Frontiers Media | Frontiers in Endocrinology
Carolina Clemente, Gonçalo Chambel, Diogo C. F. Silva, António Mesquita Montes, Joana F. Pinto, Hugo Silva,
Musculoskeletal conditions affect millions of people globally; however, conventional treatments pose challenges concerning price, accessibility, and convenience. Many telerehabilitation solutions offer an engaging alternative but rely on complex hardware for body tracking. This work explores the feasibility of a model for 3D Human Pose Estimation (HPE) from monocular 2D videos (MediaPipe Pose) in a physiotherapy context, by comparing its performance to ground truth measurements. MediaPipe Pose was ...
Tópico(s): Human Pose and Action Recognition
2023 - Multidisciplinary Digital Publishing Institute | Sensors
Isabel Valli, Àlex G. Segura, Norma Verdolini, Clemente García‐Rizo, Daniel Bergé, Inmaculada Baeza, Manuel J. Cuesta, Ana González‐Pinto, António Lobo, Anabel Martínez‐Arán, Gisela Mezquida, Laura Pina‐Camacho, Alexandra Roldán, Sergi Mas, Philip McGuire, Miquel Bernardo, Eduard Vieta,
Abstract Background Obstetric complications (OCs) are key contributors to psychosis risk. However, it is unclear whether they increase psychosis vulnerability independently of genetic risk, in interaction with it, or are a manifestation of psychosis proneness. We examined the role of distinct types of OCs in terms of psychosis risk and tested whether they interact differently with genetic vulnerability, whilst accounting for other known environmental risk factors. Study Design 405 participants (219 ...
Tópico(s): Bipolar Disorder and Treatment
2023 - Wiley | Acta Psychiatrica Scandinavica
Antonino Tuttolomondo, Claudia Colomba, Danilo Di Bona, Alessandra Casuccio, Domenico Di Raimondo, Giuseppe Clemente, Valentina Arnao, Rosaria Pecoraro, Paolo Ragonese, Anna Aiello, Giulia Accardi, Rosario Maugeri, Carlo Maida, Irene Simonetta, Vittoriano Della Corte, Domenico Gerardo Iacopino, Calogero Caruso, Antonio Cascio, António Pinto,
The HLA genes, as well as the innate immune KIR genes, are considered relevant determinants of viral outcomes but no study, to our knowledge, has evaluated their role in the clinical setting of acute viral encephalitis.Subjects with acute viral encephalitis in comparison to subjects without acute viral encephalitis showed a significantly higher frequency of 2DL1 KIR gene and AA KIR haplotypes and of HLA-C2 and HLA-A-Bw4 alleles. Subjects without acute viral encephalitis showed a higher frequency ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2018 - Impact Journals LLC | Oncotarget