Produção Nacional
Revisado por pares
Vívian T. Martins, Miguel Á. Chávez‐Fumagalli, Daniela P. Lage, Mariana C. Duarte, Esther Garde, Lourena E. Costa, Viviane G. Silva, Jamil S. Oliveira, Danielle F. de Magalhães-Soares, Santuza Maria Ribeiro Teixeira, Ana Paula Fernandes, Manuel Soto, Carlos Alberto Pereira Tavares, Eduardo Antônio Ferraz Coelho,
In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE-dependent histamine-releasing factor (HRF); to compose a polyproteins vaccine to be evaluated against L. infantum infection. Also, the antigenicity of the three proteins was analyzed, and their use for the serodiagnosis of canine visceral leishmaniasis (CVL) was evaluated. The LiHyp1, LiHyp6, and HRF DNA coding sequences were cloned ...
Tópico(s): Synthesis and Biological Evaluation
2015 - Public Library of Science | PLoS ONE
Antonio Rodríguez‐Lizana, Maria João Veloso da Costa Ramos Pereira, Manuel Ribeiro, A. Soares, Francisco Márquez‐García, Alzira Ramos, Jesús A. Gil-Ribes,
Abstract The spatial characterization of soil protection is important for preventing land degradation. Mulch covers of pruning residues are increasingly used by farmers, but little is known regarding their spatial variability. Thus, field research was conducted in a 14·7‐ha traditional olive grove located in Córdoba (Spain), to evaluate the variability of the initial density of pruning (Dp o ), tree crown volume ( V ) and N content in residues (Np). Dry pruning weight and Np were characterized in 49 and 47 ...
Tópico(s): Forest ecology and management
2017 - Wiley | Land Degradation and Development
Sandra Martins Pereira, Carla Teixeira, Orquídea Ribeiro, Pablo Hernández‐Marrero, António Manuel Fonseca, Ana Sofía Carvalho,
Enquadramento: O contacto sistemático com a morte é considerado fator de risco de burnout na saúde, particularmente para os médicos e enfermeiros que desenvolvem a sua atividade profissional em cuidados paliativos.Objetivos: Estudar a síndrome de burnout nestes profissionais, em Portugal.Metodologia: Estudo multicêntrico, de cariz quantitativo com aplicação de um questionário.Resultados: De um total de 142 profissionais, 88 devolveram o questionário devidamente preenchido; destes, somente 3% se ...
Tópico(s): Occupational Health and Burnout
2014 - Health Sciences Research Unit: Nursing (UICISA: E) | Revista de Enfermagem Referência
La Salete Martins, Sofía Pedroso, Águida Cristina Gomes Henriques, L. Dias, António Sarmento, R. Seca, Filomena Oliveira, Jorge Dores, Arnaldo Lhamas, Teresa Coelho, A. Ribeiro, Simão Esteves, Rui Pereira, R. Almeida, Morgane Amil, António Cabrita, Manuel Teixeira,
We report the 5-year results of our simultaneous pancreas-kidney transplantation (SPKT) program, started on May 2, 2000. Forty-two SPKT were performed on 42 type I diabetic patients with chronic renal failure. The procedure was performed with enteric diversion and vascular anastomosis to the iliac vessels. Immunosuppressive protocol included antithymocyte globulin, tacrolimus, mycophenolate mofetil, and steroids. The 24 women and 18 men had a mean age of 33.5 +/- 6.3 years and mean 22.8 +/- 14.2 years time ...
Tópico(s): Neurological Complications and Syndromes
2006 - Elsevier BV | Transplantation Proceedings
Produção Nacional
Revisado por pares
Diogo G. Valadares, Mariana C. Duarte, Laura Ramírez, Miguel Á. Chávez‐Fumagalli, Paula S. Lage, Vívian T. Martins, Lourena E. Costa, Tatiana G. Ribeiro, Wiliam César Bento Regis, Manuel Soto, Ana Paula Fernandes, Carlos Alberto Pereira Tavares, Eduardo Antônio Ferraz Coelho,
Tópico(s): Helminth infection and control
2012 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Ricardo Machado Xavier, Vitor Manuel Pereira Azevedo, Paulo Henrique Godoy, Arn Migowski, Antônio Luiz Pinho Ribeiro, Rogério Brant Martins Chaves, Marcelo Goulart Correia, Carolina de Aquino Xavier, Lucas de Aquino Hashimoto, Clara Weksler, Nelson Albuquerque de Souza e Silva,
Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survival. This was a retrospective study of 78,806 patients who underwent heart valve surgery between 2001 and 2007 in Brazil. Two national databases were used, the Hospital Information System and the Mortality Information System. Kaplan-Meier survival analysis and log-rank tests were performed. ...
Tópico(s): Cardiac Structural Anomalies and Repair
2017 - BioMed Central | BMC Cardiovascular Disorders
José Neves, Jorge Ribeiro, Paulo A. Pereira, Victor Alves, José Machado, António Abelha, Paulo Nováis, César Analide, Manuel Filipe Santos, Manuel Fernández-Delgado,
The analysis and development of a novel approach to asphalt pavement modeling, able to attend the need to predict the failure according to technical and non-technical criteria in a highway, is a hard task, namely in terms of the huge amount of possible scenarios. Indeed, the current state-of-the-art for service-life prediction is at empiric and empiric–mechanistic levels, and does not provide any suitable answer even for a single failure criteria. Consequently, it is imperative to achieve qualified ...
Tópico(s): Topic Modeling
2012 - Springer Science+Business Media | Progress in Artificial Intelligence
Vívian T. Martins, Miguel Á. Chávez‐Fumagalli, Daniela P. Lage, Mariana C. Duarte, Esther Garde, Lourena E. Costa, Viviane Grazielle da Silva, Jamil S. Oliveira, Danielle F. de Magalhães-Soares, Santuza Maria Ribeiro Teixeira, Ana Paula Fernandes, Manuel Soto, Carlos Alberto Pereira Tavares, Eduardo Antônio Ferraz Coelho,
Tópico(s): Trypanosoma species research and implications
2015 - Public Library of Science | PLoS ONE
Antonio Rodríguez‐Lizana, Maria João Veloso da Costa Ramos Pereira, Manuel Ribeiro, A. Soares, Leonardo Azevedo, Antonio Miranda‐Fuentes, Jordi Llorens,
Site-specific management using spatial crown volume characterization can greatly reduce the amount of pesticides applied in agricultural treatments performed with air-assisted sprayers, while helping farmers achieve the European legislation on safe use of pesticides. Nevertheless, variable rate treatments in olive groves have received little attention. Thus, field research was conducted in a 20.6-ha traditional olive grove. Two attributes of the trees – tree crown volume (V) and tree projected area – ...
Tópico(s): Remote Sensing and LiDAR Applications
2021 - Elsevier BV | The Science of The Total Environment
M. Figueroa Pedrosa, Joana Gomes, Paula Laranjeira, Cátia Duarte, Susana Pedreiro, Brígida Antunes, Tânia Ribeiro, Francisco dos Santos, António Martinho, Margarida Fardilha, M. Rosário M. Domingues, Manuel M. Abecasis, José António Pereira da Silva, Artur Paiva,
Rheumatoid arthritis (RA) is a Th1/Th17-mediated autoimmune disease whose current treatment, consisting in the blockage of inflammatory cytokines by disease-modifying antirheumatic drugs, is not effective for all patients. The therapeutic potential of mesenchymal stromal/stem cells' (MSCs) immunomodulatory properties is being explored in RA. Here, we investigate the effect of human bone marrow (BM)-MSCs on the expression of cytokines involved in RA physiopathology by the distinct functional compartments ...
Tópico(s): Oral health in cancer treatment
2019 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Produção Nacional
Revisado por pares
Arn Migowski, Rogério Brant Martins Chaves, Cláudia Medina Coeli, Antônio Luiz Pinho Ribeiro, Bernardo Rangel Tura, Maria Cristina Caetano Kuschnir, Vitor Manuel Pereira Azevedo, Daniel Brasil Floriano, Carlos Alberto Moreira Magalhães, Márcia Cristina Chagas Macedo Pinheiro, Ricardo Machado Xavier,
To evaluate the viability of a probabilistic record linkage strategy to identify patients who underwent complex cardiology procedures among the total deceased population.The processing cost was estimated based on 1,672 records of patients undergoing coronary artery bypass grafting that were compared with all death records in Brazil in 2005. The accuracy of the linkage strategy was based on the probabilistic linkage of 99 hospital admissions records of patients, with known vital status, who underwent ...
Tópico(s): Artificial Intelligence in Healthcare
2011 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Manuel Francisco Pereira, J.B. Silva, M. Chichorro,
[1] Ribeiro et al. [2007] have presented a geodynamic view of the SW Iberia Variscides based on data from Portugal. Their treatment of already published data is commendable, and the knowledge gained will surely encourage the discussion of the SW Europe Variscides. However, in our opinion, Ribeiro et al.’s modeling and interpretation of the Ediacaran–Lower Ordovician ( 560–470 Ma) geodynamic evolution are of limited value. In this regard, they based their analysis of the Ossa-Morena Zone (OMZ) on assumptions ...
Tópico(s): earthquake and tectonic studies
2009 - Wiley | Tectonics
Produção Nacional
Revisado por pares
Lourena E. Costa, Luíz Ricardo Goulart, Nathália Cristina de Jesus Pereira, Mayara Ingrid Sousa Lima, Mariana C. Duarte, Vívian T. Martins, Paula S. Lage, Daniel Menezes‐Souza, Tatiana G. Ribeiro, Maria Norma Melo, Ana Paula Fernandes, Manuel Soto, Carlos Alberto Pereira Tavares, Miguel Á. Chávez‐Fumagalli, Eduardo Antônio Ferraz Coelho,
The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display technology to identify new immunogens, which were evaluated as vaccines in the murine model of visceral leishmaniasis (VL). Epitope-based immunogens, represented by phage-fused peptides that mimic Leishmania infantum antigens, were selected according to their affinity to antibodies from asymptomatic and symptomatic VL dogs' sera.Twenty phage clones ...
Tópico(s): Trypanosoma species research and implications
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Hamilton Nenrod Pereira Teixeira, Evandro Tinoco Mesquita, Mário Luiz Ribeiro, Anna Ricordi Bazin, Cláudio Tinoco Mesquita, Manuel Pereira Teixeira, Rafael da Cunha Pellegrini, Antônio Cláudio Lucas da Nóbrega,
FUNDAMENTO: Considerando o alto número de pacientes infectados por HIV em uso de antirretrovirais, evoluindo com alteração da função endotelial e aterotrombose, levando ao alto custo médico social, é importante identificar mecanismos fisiopatológicos envolvidos com a função endotelial em portadores de HIV, para que, precocemente, possamos intervir e evitar a progressão da doença. OBJETIVO: Avaliar a função endotelial pela vasodilatação endotélio dependente e independente em pacientes HIV positivo ...
Tópico(s): HIV-related health complications and treatments
2009 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Patrícia Ribeiro, Fátima Costa, Alexandra Monteiro, Joana Caldas, Madalena Pereira da Silva, Gilda Aparecida Ferreira, Joana Veiga, Manuel O. Sousa, Maria P. Viegas, Ester Santos, António Gonçalves, Aïda Botelho de Sousa,
Tópico(s): Neutropenia and Cancer Infections
2006 - Springer Science+Business Media | Supportive Care in Cancer
Produção Nacional
Revisado por pares
Arn Migowski, Rogério Brant Martins Chaves, Cláudia Medina Coeli, Antônio Luiz Pinho Ribeiro, Bernardo Rangel Tura, Maria Cristina Caetano Kuschnir, Vitor Manuel Pereira Azevedo, Daniel Brasil Floriano, Carlos Alberto Moreira Magalhães, Márcia Cristina Chagas Macedo Pinheiro, Ricardo Machado Xavier,
OBJETIVO: Avaliar a viabilidade de estratégia de relacionamento probabilístico de bases de dados na identificação de óbitos de pacientes submetidos a procedimentos de alta complexidade em cardiologia. MÉTODOS: O custo de processamento foi estimado com base em 1.672 registros de pacientes submetidos à cirurgia de revascularização do miocárdio, relacionados com todos os registros de óbito no Brasil em 2005. A acurácia do relacionamento baseou-se em linkage probabilístico entre 99 registros de autorização ...
Tópico(s): Artificial Intelligence in Healthcare
2011 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Vívian T. Martins, Miguel A. Chávez-Fumagalli, Lourena E. Costa, Adriana Monte Cassiano Canavaci, Paula S. Lage, Daniela P. Lage, Mariana C. Duarte, Diogo G. Valadares, Rubens D. M. Magalhães, Tatiana G. Ribeiro, Ronaldo Alves Pinto Nagem, Wanderson D. DaRocha, Wiliam C. B. Régis, Manuel Soto, Eduardo Antônio Ferraz Coelho, Ana Paula Fernandes, Carlos Alberto Pereira Tavares,
Background: The present study aimed to evaluate a hypothetical Leishmania amastigote-specific protein (LiHyp1), previously identified by an immunoproteomic approach performed in Leishmania infantum, which showed homology to the super-oxygenase gene family, attempting to select a new candidate antigen for specific serodiagnosis, as well as to compose a vaccine against VL.Methodology/Principal Findings: The LiHyp1 DNA sequence was cloned; the recombinant protein (rLiHyp1) was purified and evaluated ...
Tópico(s): Glutathione Transferases and Polymorphisms
2013 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Thalita J. Bondancia, Andrey Coatrini Soares, Mário Popolin Neto, Nathalia O. Gomes, Paulo A. Raymundo‐Pereira, Hernane da Silva Barud, Sérgio Antônio Spínola Machado, Sidney J. L. Ribeiro, Matias Eliseo Melendez, André Lopes Carvalho, Rui Manuel Reis, Fernando V. Paulovich, Osvaldo N. Oliveira,
Low-cost sensors to detect cancer biomarkers with high sensitivity and selectivity are essential for early diagnosis. Herein, an immunosensor was developed to detect the cancer biomarker p53 antigen in MCF7 lysates using electrical impedance spectroscopy. Interdigitated electrodes were screen printed on bacterial nanocellulose substrates, then coated with a matrix of layer-by-layer films of chitosan and chondroitin sulfate onto which a layer of anti-p53 antibodies was adsorbed. The immunosensing ...
Tópico(s): Advanced Biosensing Techniques and Applications
2022 - Elsevier BV | Biomaterials Advances
Produção Nacional
Revisado por pares
Miguel Á. Chávez‐Fumagalli, Tatiana G. Ribeiro, Rachel Oliveira Castilho, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Cecília Steinberg Perilo Coelho, Débora V.C. Mendonça, Manuel Soto, Carlos Alberto Pereira Tavares, André Augusto Gomes Faraco, Eduardo Antônio Ferraz Coelho,
Leishmaniasis is one of the six major tropical diseases targeted by the World Health Organization. It is a life-threatening disease of medical, social and economic importance in endemic areas. No vaccine is yet available for human use, and chemotherapy presents several problems. Pentavalent antimonials have been the drugs of choice to treat the disease for more than six decades; however, they exhibit high toxicity and are not indicated for children, for pregnant or breastfeeding women or for chronically ...
Tópico(s): Synthesis and Biological Evaluation
2015 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Catarina Tomás, Emanuel Oliveira, Daniellen Cristina Ferreira Sousa, Matheus Uba Chupel, Guilherme Eustáquio Furtado, Clara Rocha, Ana Teixeira, Pedro Lopes Ferreira, C. Alves, Stefan Gisin, Elisabete Catarino, Nelma Carvalho, Tiago Coucelo, Luís Américo Silva Bonfim, Carina Silva, Débora Franco, Jesús Alcoba González, Maria Helena de Agrela Gonçalves Jardim, Rita Silva, Cristina Lavareda Baixinho, Ma Helena Presado, Ma Fátima Marques, Mário E. Cardoso, Marina Cunha, Joana Mendes, Ana Xavier, Ana Galhardo, Margarida Couto, João Frade, Carla Nunes, João R. Mesquita, María Säo José Nascimento, Guilherme Gonçalves, Conceição Castro, Alice Mártires, M. João Monteiro, Conceição Rainho, Francisco P. Caballero, Fátima M. Monago, José T. Guerrero, Rocio M. Monago, Africa P. Trigo, Milagros L. Gutierrez, Gemma M. Milanés, Mercedes G. Reina, Ana G. Villanueva, Ana S. Piñero, Isabel R. Aliseda, Francisco Buitrago Ramírez, Andrea Ribeiro, Ana Quelhas, Maria Conceição Manso, Francisco P. Caballero, José T. Guerrero, Fátima M. Monago, Rafael Brito Santos, Nuria R. Jimenez, Cristina G. Nuñez, Inmaculada Rodríguez Gómez, Ma Jose L. Fernandez, Laura A. Marquez, Ana L. Moreno, Ma Jesus Tena Huertas, Francisco Buitrago Ramírez, Daniel Seabra, Ma Céu Salvador, Luciene Muniz Braga, Pedro Parreira, Anabela Salgueiro‐Oliveira, Cristina Arreguy-Sena, Bibiana F. Oliveira, Ma Adriana Henriques, Joana Santos, Sara Lebre, Alda Marques, Clarinda Festas, Sandra Rodrigues, Andrea Ribeiro, José Lumini‐Oliveira, Ana Gabriela Figueiredo, Francisco J. Hernandez-Martinez, Liliana Campi, Ma Pino Quintana-Montesdeoca, Juan F. Jimenez-Diaz, Bienvenida C. Rodriguez-De-Vera, Alexandra Parente, Ma Augusta Mata, Ana Ma Pereira, Adília Fernandes, Manuel Brás, Ma Rosário Pinto, Pedro Parreira, Marta Lima Basto, Ana C. Rei, Lisete Mónico, Gilberta Sousa, Clementina Morna, Otília Freitas, Gregório Freitas, Ana Carolina Gomes Jardim, Rita P. Vasconcelos, Lina G. Horta, Roger dos Santos Rosa, Luís Fernando Kranz, Rita C. Nugem, Mariana Santiago Siqueira, Ronaldo Bordin, Rosiane Kniess, Josimari Telino de Lacerda, Joana Guedes, Idalina Machado, Sidalina Almeida, Adriano Zilhão, Hélder Alves, Óscar Ribeiro, Ana Paula Martins Amaral, Ana Maria Ribeiro dos Santos, Joana Monteiro, Ma Clara Rocha, Rui Cruz, Ana Paula Martins Amaral, Marina Lourenço, Ma Clara Rocha, Rui Cruz, Sandra Regina Masetto Antunes, Verónica Mendonça, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, Antonio Padua y Gabriel, Anabela Correia Martins, Fernando Mendes, Lídia Cabral, Manuela Ferreira, Amadeu Gonçalves, Tatiana Durão D`Ávila Luz, Leonardo Gomes de Oliveira Luz, Raúl A. Martins, Alice Murteira Morgado, Maria da Luz Vale-Dias, Rui Porta-Nova, Tânia Cristina Malezan Fleig, Éboni Marília Reuter, Miriam Beatris Froemming, Sabrina Luciane Camara Guerreiro, Lisiane Lisbôa Carvalho, Daniel Guedelha, Pedro S. Coelho, A.T. Pereira, António Calha, Raúl Cordeiro, Ana Gonçalves, Ana Certo, Ana Cristina Araújo de Andrade Galvão, Ma Augusta Mata, Aline Welter, Elayne Crestani Pereira, Sandra Aparecida Ribeiro, Márcia Regina Kretzer, Juan-Fernando Jiménez-Díaz, Carla Jiménez-Rodríguez, Francisco-José Hernández-Martínez, Bienvenida-Del-Carmen Rodríguez-De-Vera, Alexandre Marques-Rodrigues, Patrícia Brazil Pereira Coelho, Tiago Bernardes, Alexandre de Araújo Pereira, Patrícia Sousa, João Ghizzo Filho, Nazaré Otília Nazário, Márcia Regina Kretzer, Odete Amaral, António Garrido, Nélio Veiga, Carla Nunes, Ana Rita Pedro, Carlos Pereira, António Almeia, Hélder Miguel Fernandes, Carlos Vasconcelos, Nélson Sousa, Víctor Machado Reis, M. João Monteiro, Romeu Mendes, Isabel Pinto, Tânia C. S. P. Pires, João Gama, Vera Preto, Norberto Silva, Carlos Pires Magalhães, Matilde Martins, Mafalda Duarte, Constança Paúl, Ignácio Martín, Arminda Pinheiro, Sandra Doria Xavier, J. Azevedo, E. Bento, C. Marques, M. Marques, A. Macedo, A.T. Pereira, José Pedro Almeida, António Almeida, Josiane Alves, Nélson Sousa, Francisco Saavedra, Romeu Mendes, Ana S. Maia, Michelle Teixeira Oliveira, Anderson Reis de Sousa, Paulo P. Ferreira, Luci S. Lopes, Eujcely C. Santiago, Sílvia Monteiro, Ângelo Jesus, Armanda Colaço, Antônio Ivo de Carvalho, Rita P. Silva, Agostinho Cruz, Ana Ferreira, Catarina Marques, João Paulo Figueiredo, Susana Paix�ão, Ana Ferreira, Carla Lopes, Fernando Moreira, João Paulo Figueiredo, Ana Ferreira, Diana Ribeiro, Fernando Moreira, João Paulo Figueiredo, Susana Paix�ão, Telma Fernandes, Diogo Amado, Jéssica Denise Vieira Leal, Marcelo Costa Velho Mendes de Azevedo, Sónia Ramalho, Catarina Mangas, Jaime Ribeiro, Rita Maria de Abreu Gonçalves, Amélia Fernandes Nunes, Ana Rita Tuna, Carlos Martins, Henriqueta D. Forte, Cláudia Costa, José António Tenedório, Paula Santana, José Augusto Andrade, Joana Pinto, C. Campofiorito, S. C. Nunes, Ana Sofia Carmo, A. Kaliniczenco, Bárbara Erllen da Silva Alves, Francisco Mendes, Carlos Jesus, Felipe Paiva Fonseca, Flávia de Sousa Gehrke, Carlos Albuquerque, Rita Batista, Madalena Cunha, António Dias, Olivério Ribeiro, Rosa Maria Grangeiro Martins, Teresa Madeira, Catarina Peixoto-Plácido, Nuno Rebelo dos Santos, Osvaldo Santos, Astrid Bergland, Asta Bye, Carla Lopes, Violeta Alarcão, Beatriz Goulão, Nuno Mendonça, Paulo Nicola, J. Gorjão Clara, João Gomes, Ana Querido, Catarina Tomás, Daniel Carvalho, Marina Cordeiro, Marlene Rosa, Alda Marques, Daniela Brandão, Óscar Ribeiro, Lia Araújo, Constança Paúl, Beatriz Minghelli, Sylvina Richaud, Ana Laura Mendes, Joana Marta‐Simões, Inês A. Trindade, Cláudia Ferreira, Teresa Carvalho,
S1 Health literacy and health education in adolescence Catarina Cardoso Tomás S2 The effect of a walking program on the quality of life and well-being of people with schizophrenia Emanuel Oliveira, D. Sousa, M. Uba-Chupel, G. Furtado, C. Rocha, A. Teixeira, P. Ferreira S3 Diagnosis and innovative treatments - the way to a better medical practice Celeste Alves S4 Simulation-based learning and how it is a high contribution Stefan Gisin S5 Formative research about acceptability, utilization and promotion ...
BioMed Central
Produção Nacional
Revisado por pares
Arn Migowski, Antônio Luiz Pinho Ribeiro, Marília Sá Carvalho, Vitor Manuel Pereira Azevedo, Rogério Brant Martins Chaves, Lucas de Aquino Hashimoto, Carolina de Aquino Xavier, Ricardo Machado Xavier,
The efficacy of implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy-defibrillator (CRT-D) therapy has already been established in clinical trials but their effectiveness in several clinical settings remains undetermined. This study aimed to assess the effectiveness of ICD and CRT-D therapies within the Brazilian National Health System (SUS). All patients who underwent ICD or CRT-D implantation within the SUS from 2001 to 2007 were included in the study. We compared estimated ...
Tópico(s): Cardiomyopathy and Myosin Studies
2015 - BioMed Central | BMC Cardiovascular Disorders
Paula Laranjeira, M. Figueroa Pedrosa, Cátia Duarte, Susana Pedreiro, Brígida Antunes, Tânia Ribeiro, Francisco dos Santos, António Martinho, Margarida Fardilha, M. Rosário M. Domingues, Manuel M. Abecasis, José António Pereira da Silva, Artur Paiva,
Rheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA. This study aimed to explore the immunomodulatory action of human bone marrow (BM)-MSCs on myeloid dendritic cells (mDCs) and monocytes, especially on cytokines/chemokines involved in RA physiopathology. For that, LPS plus IFNγ-stimulated peripheral blood mononuclear ...
Tópico(s): Orthopedic Infections and Treatments
2022 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Revisado por pares
Mariana C. Duarte, Grasiele S.V. Tavares, Diogo G. Valadares, Daniela P. Lage, Tatiana G. Ribeiro, Letícia M.R. Lage, Marcella Rezende Rodrigues, André Augusto Gomes Faraco, Manuel Soto, Eduardo Sérgio da Silva, Miguel Á. Chávez‐Fumagalli, Carlos Alberto Pereira Tavares, João Paulo Viana Leite, Jamil S. Oliveira, Rachel Oliveira Castilho, Eduardo Antônio Ferraz Coelho,
In recent years, considerable attention has been given to identify new antileishmanial products derived from medicinal plants, although, to date, no new effective compound has been recently applied to treat leishmaniasis. In the present study, the antileishmanial activity of a water extract from Zingiber officinalis Roscoe (ginger) was investigated and a purified fraction, named F10, was identified as responsible by this biological activity. The chemical characterization performed for this fraction ...
Tópico(s): Phytochemistry and biological activities of Ficus species
2016 - Elsevier BV | Experimental Parasitology
Hélder Pereira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Rui Cruz Ferreira, Vasco da Gama Ribeiro, Ricardo Santos de Oliveira, Pedro Farto e Abreu, Henrique Carvalho, Jorge Marques, Renato Fernandes, Vítor Brandão, Dinis Martins, António Drummond, João Pipa, Luís Seca, João Calisto, José Baptista, Fernando Matias, J. Sousa Ramos, Francisco Pereira‐Machado, João C. Silva, Manuel Almeida,
The aim of the present paper is to report trends in Portuguese interventional cardiology from 2004 to 2013 and to compare them with other European countries.Based on the Portuguese National Registry of Interventional Cardiology and on official data from the Directorate-General of Health, we give an overview of developments in coronary interventions from 2004 to 2013.In 2013, 36 810 diagnostic catheterization procedures were performed, representing an increase of 34% compared to 2007 and a rate of ...
Tópico(s): Cardiac Imaging and Diagnostics
2015 - Elsevier BV | Revista Portuguesa de Cardiologia
Renato Kaufman, Maria Cristina Caetano Kuschnir, Regina Maria Aquino Xavier, Marco Santos, Rogério Brant Martins Chaves, R Müller, Márcia Cristina Chagas Macedo Pinheiro, Antônio da Silva Ribeiro, Vitor Manuel Pereira Azevedo,
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2011 - Sociedade Brasileira de Virologia | International Journal of Cardiovascular Sciences
Manuel Ribeiro, Maria João Veloso da Costa Ramos Pereira, A. Soares, Cristina Branquinho, Sofia Augusto, Esteve Llop, Susana Fonseca, Joaquim Gil Nave, António Barata Tavares, Carlos Matias Dias, Ana Silva, Ismael Selemane, Joaquin de Toro, Mário J. Santos, Fernanda Batista Oliveira Santos,
The present study protocol is designed to assess the relationship between outdoor air pollution and low birth weight and preterm births outcomes performing a semi-ecological analysis. Semi-ecological design studies are widely used to assess effects of air pollution in humans. In this type of analysis, health outcomes and covariates are measured in individuals and exposure assignments are usually based on air quality monitor stations. Therefore, estimating individual exposures are one of the major ...
Tópico(s): Radioactivity and Radon Measurements
2010 - BioMed Central | BMC Public Health
Produção Nacional
Revisado por pares
Eduardo Antônio Ferraz Coelho, Tatiana Ribeiro, Leonardo Lima Fuscaldi, María José Santos, Mariana Duarte, Paula S. Lage, Vívian T. Martins, Lourena E. Costa, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Rachel Oliveira Castilho, Manuel Soto, Carlos Alberto Pereira Tavares, Miguel Á. Chávez‐Fumagalli, Jucara Ribeiro, André Augusto Gomes Faraco,
Abstract: Amphotericin B (AmpB) is active against leishmaniasis, but its use is hampered due to its high toxicity observed in patients. In this study, a nanoparticles-delivery system for AmpB (NQC-AmpB), containing chitosan and chondroitin sulfate molecules, was evaluated in BALB/c mice against Leishmania amazonensis . An in vivo biodistribution study, including biochemical and toxicological evaluations, was performed to evaluate the toxicity of AmpB. Nanoparticles were radiolabeled with technetium- ...
Tópico(s): Trypanosoma species research and implications
2014 - Dove Medical Press | International Journal of Nanomedicine
Hélder Pereira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Rui Cruz Ferreira, Vasco da Gama Ribeiro, Ricardo Santos de Oliveira, Pedro Farto e Abreu, Henrique Carvalho, Jorge Marques, Renato Fernandes, Vítor Brandão, Dinis Martins, António Drummond, João Pipa, Luís Seca, João Calisto, José Baptista, Fernando Matias, J. Sousa Ramos, Francisco Pereira‐Machado, João Carlos Silva, Manuel Almeida,
The aim of the present paper is to report trends in Portuguese interventional cardiology from 2004 to 2013 and to compare them with other European countries. Based on the Portuguese National Registry of Interventional Cardiology and on official data from the Directorate-General of Health, we give an overview of developments in coronary interventions from 2004 to 2013. In 2013, 36 810 diagnostic catheterization procedures were performed, representing an increase of 34% compared to 2007 and a rate ...
Tópico(s): Acute Myocardial Infarction Research
2015 - Elsevier BV | Revista Portuguesa de Cardiologia (English Edition)
Produção Nacional
Revisado por pares
Frédéric Labbé, Maha Abdeladhim, Jenica Abrudan, Alejandra Saori Araki, Ricardo N. Araújo, Peter Arensburger, Joshua B. Benoit, Reginaldo Peçanha Brazil, Rafaela Vieira Bruno, Gustavo Bueno da Silva Rivas, Vinicius Carvalho de Abreu, Jason Charamis, Iliano V. Coutinho-Abreu, Samara Costa, Alistair C. Darby, Viv M. Dillon, Scott Emrich, Daniela Fernandez-Medina, Nelder F. Gontijo, Catherine M. Flanley, Derek Gatherer, Fernando Ariel Genta, Sandra Gesing, Gloria I. Giraldo-Calderón, Bruno Gomes, Eric Roberto Guimarães Rocha Aguiar, James G. Hamilton, Omar Hamarsheh, Mallory Hawksworth, Jacob M. Hendershot, Paul V. Hickner, Jean‐Luc Imler, Panagiotis Ioannidis, Emily C. Jennings, Shaden Kamhawi, Charikleia Karageorgiou, Ryan Kennedy, Andreas Krueger, José Manuel Latorre-Estivalis, Petros Ligoxygakis, Antonio C.A. Meireles-Filho, Patrick Minx, José Carlos Miranda, Michael J. Montague, Ronald J. Nowling, Fabiano Oliveira, João Ramalho Ortigão‐Farias, Márcio G. Pavan, Marcos H. Pereira, André Nóbrega Pitaluga, Roenick Proveti Olmo, Marcelo Ramalho-Ortigão, José M. C. Ribeiro, Andrew J. Rosendale, Maurício Roberto Viana Sant’Anna, Steven E. Scherer, Nágila Francinete Costa Secundino, Douglas A. Shoue, Caroline da Silva Moraes, João Silveira Moledo Gesto, Nataly A. Souza, Zainulabueddin Syed, Samuel Tadros, Rayane Teles-de-Freitas, Erich Loza Telleria, Chad Tomlinson, Yara Maria Traub-Csekö, João T. Marques, Zhijian Tu, Maria Unger, Jesús G. Valenzuela, Flávia V. Ferreira, Karla Pollyanna Vieira de Oliveira, Felipe M. Vigoder, John Vontas, Lihui Wang, Gareth D. Weedall, Elyes Zhioua, Stephen Richards, Wesley C. Warren, Robert M. Waterhouse, Rod J. Dillon, Mary Ann McDowell,
Phlebotomine sand flies are of global significance as important vectors of human disease, transmitting bacterial, viral, and protozoan pathogens, including the kinetoplastid parasites of the genus Leishmania , the causative agents of devastating diseases collectively termed leishmaniasis. More than 40 pathogenic Leishmania species are transmitted to humans by approximately 35 sand fly species in 98 countries with hundreds of millions of people at risk around the world. No approved efficacious vaccine ...
Tópico(s): Trypanosoma species research and implications
2023 - Public Library of Science | PLoS neglected tropical diseases
Pedro Ferreira Pereira, Manuel Ribeiro da Silva, Ricardo São Simão, Pedro Negrão, António Sousa, Nuno Nevès,
Hindfoot ulcers associated with chronic calcaneus osteomyelitis are very difficult to manage and many patients need a limb amputation for resolution. Total calcanectomy can be a salvage procedure for these patients. The purpose of this study is to present our results of total calcanectomy.Retrospective analysis of six patients undergoing total calcanectomy at our institution between 2008 and 2019. Patient data and ambulatory status were analyzed.In 4 of the 6 patients, infection control and wound ...
Tópico(s): Wound Healing and Treatments
2021 - Elsevier BV | The Foot