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Artigo Revisado por pares

Eduarda M. P. Silva, Francesca Giuntini, M. Amparo F. Faustino, João P. C. Tomé, Maria G. P. M. S. Neves, Augusto C. Tomé, Artur M. S. Silva, M.G. Santana-Marques, A. J. Ferrer‐Correia, José A. S. Cavaleiro, Maria Filomena Caeiro, Ricardo R. Duarte, Sabina A.P. Tavares, Inês N. Pegado, Bruno d’Almeida, António Matos, Maria Luísa Valdeira,

An easy route to cationic β-vinyl substituted meso-tetraphenylporphyrin derivatives is described. Two novel compounds were tested in vitro for their antiviral photoactivity against herpes simplex virus type 1. One of these compounds exhibited a significant activity, reaching 99% of virus inactivation after 15 min of photoactivation.

Tópico(s): Nanoplatforms for cancer theranostics

2005 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters

Artigo Acesso aberto Revisado por pares

Teresa Almeida, Andreia Ruivo, António Pires de Matos, Rosa Maria de Oliveira, Aquino Antunes,

In this study the application of luminescent glasses under UV light in artworks is explored.Several lanthanide oxides were used in the glass composition to obtain different colours.A brief comparison with the conventional glass artwork using neon is made.Future conservation was taken into account and the compatibility studies of mixtures of different glasses were studied.

Tópico(s): Lanthanide and Transition Metal Complexes

2008 - Elsevier BV | Journal of Cultural Heritage

Artigo Revisado por pares

António Matos, Maria Filomena Caeiro, Tibor Papp, Bruno André da Cunha Almeida Matos, Ana Cristina Lacerda Correia, Rachel E. Marschang,

Lizard erythrocytic viruses (LEVs) have previously been described in Lacerta monticola from Serra da Estrela, Portugal. Like other known erythrocytic viruses of heterothermic vertebrates, these viruses have never been adapted to cell cultures and remain uncharacterized at the molecular level. In this study, we made attempts to adapt the virus to cell cultures that resulted instead in the isolation of a previously undetected Ranavirus closely related to FV3. The Ranavirus was subsequently detected ...

Tópico(s): Amphibian and Reptile Biology

2010 - Oxford University Press | Microscopy and Microanalysis

Artigo Revisado por pares

Helena Correia, Cristina Soares, Simone Morais, Edgar Pinto, Antònio Marques, María Leonor Nunes, Agostinho Almeida, Cristina Delerue‐Matos,

Considering the importance of seaweeds for the development of sustainable and innovative food products, this study aimed to characterize the impact of hydrothermal processing on iodine, sodium, potassium, selenium, and arsenic concentrations of four seaweed species (S. latissima, L. digitata, U. pinnatifida, and C. crispus) and on the associated health risks-benefits for consumers. These elements revealed a common pattern for leachable fractions of iodine, total arsenic, and selenium: L. digitata ≥ ...

Tópico(s): Selenium in Biological Systems

2021 - Elsevier BV | Food and Chemical Toxicology

Artigo Acesso aberto Revisado por pares

Ana Usié, Fernanda Simões, Pedro Barbosa, Brígida Meireles, Inês Chaves, Sónia Gonçalves, André Folgado, Maria Helena Almeida, José Matos, António Marcos Ramos,

Cork oaks show a high capacity of bud sprouting as a response to injury, which is important for species survival when dealing with external factors, such as drought or fires. The characterization of the cork oak transcriptome involved in the different stages of bud sprouting is essential to understanding the mechanisms involved in these processes. In this study, the transcriptional profile of different stages of bud sprouting, namely (1) dormant bud and (2) bud swollen, vs. (3) red bud and (4) open ...

Tópico(s): Plant Water Relations and Carbon Dynamics

2017 - Multidisciplinary Digital Publishing Institute | Forests

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Sandra R. Almeida-Carvalho, Maria L. Gomes-Ferraz, Carla A. Loureiro-Matos, Antônio E. Benedito-Silva, Roberto José de Carvalho‐Filho, Rogério Renato-Perez, Adriano Miziara Gonzalez, Alcides Augusto Salzedas Netto, Dênis Szejnfeld, Giuseppe D’Ippolito, Valéria Pereira-Lanzoni, Ivonete S. Souza-Silva,

Background. Hepatocellular carcinoma (HCC) is the most common malignancy that develops in cirrhotic livers. Its clinical and epi-demiological characteristics and mortality rates vary according to geographical region. The objective of this study was to evaluate the clinical profile, epidemiological characteristics, laboratory parameters, treatment and survival of patients with HCC. Material and methods. Patients with HCC seen between 2000 and 2012 were studied. The Kaplan-Meier method was used for ...

Tópico(s): Liver Disease and Transplantation

2017 - Elsevier BV | Annals of Hepatology

Artigo Brasil Produção Nacional Revisado por pares

Roberta Falcão Tanabe, Zina Maria Almeida de Azevedo, Vânia Matos Fonseca, Maria Virgínia Marques Peixoto, Luiz Antônio dos Anjos, Maria Ignez C. Gaspar−Elsas, Daniella Campelo Batalha Cox Moore, Eloane Gonçalves Ramos,

Ethnicity may influence bioimpedance values. The goal of this study was to measure total body impedance vector in infants and pre-school children in Brazil and compare them with those reported in other countries.We analyzed bioelectrical impedance from a sample of 255 healthy Brazilian children, aged 1-36 months, using the RXc graph method (tetrapolar analysis at 50 kHz frequency). The 95%, 75% and 50% tolerance ellipses were plotted by age group.The mean impedance vector showed migration across ...

Tópico(s): Body Composition Measurement Techniques

2011 - Elsevier BV | Clinical Nutrition

Artigo Acesso aberto Revisado por pares

Gonçalo M. Rosa, Gonçalo Ayala Botto, Amartya T. Mitra, João Simões de Almeida, Max Hofmann, William T. M. Leung, António Matos, Maria Filomena Caeiro, Elsa Froufe, Armando Loureiro, Stephen J. Price, Christopher G. Owen, Rui Rebelo, Cláudia Soares,

Sudden disease outbreaks may not necessarily reflect a recent pathogen introduction but may instead arise from the disruption of a host-pathogen equilibrium. Together with invasive species, emerging pathogens pose significant threats to biodiversity. The dynamics of each stressor have been studied separately, yet rarely when interacting. Using a 40-year dataset, we tested the hypothesis that the introduction of an invasive fish leads to such a disruption, manifested by ranavirosis outbreaks on amphibian ...

Tópico(s): Zoonotic diseases and public health

2022 - Elsevier BV | Biological Conservation

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Carla Virgínia Vieira Rollemberg, Cybele Maria Bomfim Santos, Marília Matos Bezerra Lemos Silva, Acacia Maria Barros Souza, Ângela Maria da Silva, José Antônio Pacheco de Almeida, Roque Pacheco de Almeida, Amélia Ribeiro de Jesus,

INTRODUÇÃO: A esquistossomose é endêmica no Brasil, com elevada prevalência no Estado de Sergipe, apesar da existência do Programa de Controle da Esquistossomose (PCE). MÉTODOS: Foi realizado levantamento de dados do PCE-Sergipe de 2005 a 2008. A partir da matriz bruta formulou-se planilha de dados no software Access e analisou-se frequência e distribuição geográfica das infecções por Schistosoma mansoni e outros enteroparasitos. Estes dados foram exportados para o software Spring 5.0.5 para georreferenciamento ...

Tópico(s): Child Nutrition and Water Access

2011 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paulo A. Lotufo, Raúl D. Santos, Roberta Carvalho de Figueiredo, Alexandre C. Pereira, José Geraldo Mill, Sheila Maria Alvim Matos, Maria Jesus Mendes Fonseca, Maria da Conceição Chagas de Almeida, M. Carmen Molina, Dóra Chor, María Inês Schmidt, Antônio Luiz Pinho Ribeiro, Bruce Bartholow Duncan, Isabela M. Benseñor,

Dyslipidemia is a pivotal risk factor for coronary heart disease (CHD). The purpose of this study was to identify the profile of dyslipidemia in a Brazilian population, according to high low-density lipoprotein (LDL-C) levels. We used the classification of the 2004 update of National Cholesterol Education Program Adult Treatment Panel III (ATP-III).Of the 15,105 men and women aged 35 to 74 years enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), we included 14,648 subjects (97%). ...

Tópico(s): Health Systems, Economic Evaluations, Quality of Life

2016 - Elsevier BV | Journal of clinical lipidology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Manoel Medeiros, Joanemile P. Figueiredo, Maria Cecília Almeida, Maria Analia Matos, Maria Ilma Araújo, Álvaro A. Cruz, Ajax Mercês Atta, Marco Antônio Vasconcelos Rêgo, Amélia Ribeiro de Jesus, Ernesto Akio Taketomi, Edgar M. Carvalho,

Background: Helminthic infections decrease skin reactivity to indoor allergens, but data on whether they influence asthma severity are lacking. Objective: This study evaluated the course of asthma in patients with and without Schistosoma mansoni infection. Methods: Asthmatic subjects were enrolled from 3 low-socioeconomic areas: a rural area endemic for schistosomiasis (group 1) in addition to a rural area (group 2) and a slum area (group 3), both of which were not endemic for schistosomiasis. A questionnaire ...

Tópico(s): Child Nutrition and Feeding Issues

2003 - Elsevier BV | Journal of Allergy and Clinical Immunology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Xiaochen Lin, Sheila Maria Alvim Matos, Eduardo J. Simões, Isabela M. Benseñor, Sandhi Maria Barreto, María Inês Schmidt, Antônio Luiz Pinho Ribeiro, Francisco José Gondim Pitanga, Maria da Conceição Chagas de Almeida, Simin Liu, Paulo A. Lotufo,

Background Although increasing effort has been devoted to the promotion of a healthy lifestyle such as leisure time physical activity for cardio‐metabolic health, specific evidence supporting health policy remains sparse, particularly in those ethnically diverse populations where cardio‐metabolic diseases are reaching epidemic proportion and yet are grossly understudied. Methods and Results We conducted a cross‐sectional analysis of the baseline data from 10 585 participants aged 35 to 74 free of ...

Tópico(s): Health and Lifestyle Studies

2016 - Wiley | Journal of the American Heart Association

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Joycy Francely Sampaio dos Santos, Janaína Esmeraldo Rocha, Camila Fonseca Bezerra, Maria Karollyna do Nascimento Silva, Yedda Maria Lobo Soares de Matos, Thiago Sampaio de Freitas, Antônia Thassya Lucas dos Santos, Rafael Pereira da Cruz, Antônio Júdson Targino Machado, Tigressa Helena Soares Rodrigues, Edy Sousa de Brito, Dédora Lima Sales, Waltécio de Oliveira Almeida, José Galberto Martins da Costa, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais‐Braga,

The development of fungal resistance to antifungal drugs has been worsening over the years and as a result research on new antifungal agents derived from plants has intensified. Eugenia uniflora L. (pitanga) has been studied for its various biological actions. In this study the chemical composition and antifungal effects of the E. uniflora essential oil (EULEO) were investigated against Candida albicans (CA), Candida krusei (CK) and Candida tropicalis (CT) standard strains. The essential oil obtained ...

Tópico(s): Antifungal resistance and susceptibility

2018 - Elsevier BV | Food Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Flávia Ribeiro Machado, Alexandre Biasi Cavalcanti, Mariana Barbosa Monteiro, Juliana Lubarino Sousa, Aline Siqueira Bossa, Antônio Tonete Bafi, Felipe Dal‐Pizzol, F Freitas, Thiago Lisboa, Glauco Adrieno Westphal, André Miguel Japiassú, Luciano César Pontes Azevedo, Rosane Maria Souza Costa Brandão, Yelnya Cardoso Silva Dória, Mônica Rocha de Melo Silva, Antonieta de Sousa Castro, Andre Luis Coutinho de Araujo Macedo, Ianna Lacerda Sampaio Braga, Nathane Carolina Vieira de Sales, Allan Christian Cardoso Cembranel, Carlos Álvaro Corrêa Araújo, Adriana da Costa Barros, Werciley Saraiva Vieira, Mariane Conceição Paixão, Guilherme Marrêta Cavalcanti Ayres, Patricia Moreira de Araújo Lisboa, Pedro Ivandosvick Cordeiro de Oliveira, Narhayanne Kondratievans, Nafel Rosa Toledo, Priscilla Alexandrini de Oliveira, Elisangela Brunetti de Melo, SILVÉRIO LEONARDO MACEDO GARCIA, Simone Martins Gonçalves, Livia Magdalena Martínez Borja, Maria Amelia Ferreira Rocha, Mariana Avendanha Victoriano, Priscila Portes Almeida, Gilvânia Cristina Silva Oliveira, Marcelo Dias M. de Assis Costa, Mário Sergio Prado, Aldo Peixoto de Melo, Cristina Pereira, Márcia Gregory Tavares Melo, Claudia M. Starling, Marcelo Silva de Oliveira, Angela de Fátima Borges, Lidiane Miranda Milagres, Maria Augusta de Mendonça Lima, C Ribeiro, Fabiana Soares Santos, Rejane Fernandes Queiroz Andrade, Maria Márcia Caetano Silva, Orlando César Mantese, R Cunha, Edmilson Antônio Mariano, Fabrícia Moreira Amorim, Edgar de Brito Sobrinho, Milce Hellen Barros de Oliveira, Adrian Oliveira Lameira Veríssimo, Gustavo Spangenberg Tarre Borges, Ana Carolina Dino Durda, Kamila Lira Jatoba, Renata Alessandra Sadowski, César Helbel, Gilselena Kerbauy, Cíntia Magalhães Carvalho Grion, Caroline Tolentino Sanches, Camila Brito Borguezam, Cíntia Magalhães Carvalho Grion, Fernanda Esteves Nascimento Barros, Beatriz da Silva Carvalho, Rosânia Maria de Araújo Oliveira, Marcus Otávio Torres Vieira, Isabelle Araujo Barros, Marilene Aparecida Batista da Silva, Bruno Franco Mazza, Francilene de Oliveira Mendes, Moyzes Pinto Coelho Duarte Damasceno, Mozart Bellas Rodrigues, Danilo Abreu dos Santos F. da Silva, R. Calheiros, Juana Souto Jardim, Antonio Felix Pereira, Monica Guedes Rodrigues, Luis Eduardo Santos Fontes, Lucia P. Coelho, L. Kling, Giselle Rouvenat Accioly, Edmundo de Oliveira Tommasi, Maurício Osvaldo Moura, Fábio Guilherme Santoro, Marcelo Foradini de Albuquerque, Luciana Wilken Roderjan, Elane Moreira de Mattos, Ranieri Carvalho Leitão, Marcelo London, V Cravo, Giovanna Camacho Asturi, Felipe Luiz de Castro Pereira, Giovana Colozza Mecatti, Thiago Corsi Filiponi, Felipe Pires Barbosa, Gilberto Friedman, Rafael Barberena Moraes, Jaqueline Sangiogo Haas, Glauco Adrieno Westphal, Álvaro Köenig, Renata Peralta Fujiwara, Alexandre Habitante, D Sa Couto, Gisele Oliveira, Marlene Pereira de Aguia, Antonio Claudomiro Aparecido Beneventi, Carlos Augusto Jacob, Alexandra Silva, Mariana Yumi Okada, Nilza Sandra Lasta, Lívia Maria Garcia Melro, Carolina Paparelli Lourenço, Ciro Parioto Neto, Antonielle Figueirêdo Macêdo, Lucas Seabra Fernandes, Bruno Adler Maccagnan Pinheiro Besen, Nislene Barbosa Viana, Karina Daniela Araujo Gomes Coqueti, Fabio de Carvalho Maurício, Isabela Miranda Lopes, Amadeu Fuzita Lopes, Barbara da Silva Del Orti, José Antônio Manetta, Rodnei de Freitas Baião, Cristiano Ramos de Morais, Otávio Monteiro Becker, Diogo Boldim Ferreira, Paula Tuma, Nayara Rodrigues da Silva, Margarete Vilins, Eveline Silva Santos, Letícia Sandre Vendrame, Viviane Kiuti, Fernanda Maciel Paschoin, Érika Simões Mesquita Valim Moreir, Graziela Moreira Xavier, Wagner Santa Catharina, Alcides Félix Terrível, Joaquim StoraniNeto, Marcos Antônio Cyrillo, Jose Eduardo Vasconcellos, P. A. Leandro, Luciano Severino da Silva, Marcela Portugal de Alencar Ribeiro, Andrea Magna Patriota de Oliveira, Eduardo de Souza Pacheco, Andreia Lima, Linus Pauling Fascina, Juliana Celli, Ricardo Ota Pereira, Pedro Ivo Monteiro Pacheco, Cristiane Maria Clares de Araujo Moreno, Fabiana Barros de Almeida, José Antonio Almeida da Rocha, Aline Siqueira Bossa, Alexandre de Matos Soeiro, Múcio Tavares de Oliveira, Jorge Fares, Horácio José Ramalho, Márcia Cristina Lopes, Selma Pereira de Santana, Mariana Volpe Arnoni, Fernanda Maffei, Juliana Vila Chã Bueno, R. Tambelli, Luciana Pedral Sampaio Sgarbi, Roseli Calil, Carolina C. Ribeiro‐do‐Valle, Vanessa Aparecida Vilas-Boas, Ana Paula Fernandes Fadoni, Brígida Aparecida Rosa dos Reis, Mônica Ducchi, Luiz Fumio Matsumoto, Elisabete Ribeiro Insoliti, R. Vasconcelos, Vinícius Avellar Werneck, Sabrina Bernárdez Pereira, Bruno Gonçalves de Campos Araujo, Josiane Francisca Ferreira, Rafael Di Domenico Mattos, Mirani Lucia Monteiro, Rodrigo dos Santos Nascimento, Izac Alessandro Batista de Souza, André Luiz Honório Cardoso, Miguel Villa Nova Soeiro, Fernando Côrtes Remisio Figuinha, Mario Sérgio Moreno, Bruna Augusta Oliveira Pagliaro, Maria Beatriz Bonin Caraccio, Juliana Vidal Sartori de Carvalho, Luiz Eduardo Miranda Paciência, Humberto Bolognini Tridapalli, Lidia Fabiana da Silva Manske, Rafaela Mamus Correa Tridapalli,

Rationale: Although proposed as a clinical prompt to sepsis based on predictive validity for mortality, the Quick Sepsis-related Organ Failure Assessment (qSOFA) score is often used as a screening tool, which requires high sensitivity.Objectives: To assess the predictive accuracy of qSOFA for mortality in Brazil, focusing on sensitivity.Methods: We prospectively collected data from two cohorts of emergency department and ward patients. Cohort 1 included patients with suspected infection but without ...

Tópico(s): Disaster Response and Management

2020 - American Thoracic Society | American Journal of Respiratory and Critical Care Medicine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gabriel Augusto Marques Rossi, Heloisa Adélia Stefanoni de Simoni, Welber Daniel Zanetti Lopes, Henrique Meiroz de Souza Almeida, Vando Edésio Soares, Ana Maria Centola Vidal, Antônio Sérgio Ferraudo, Luís Antônio Mathias,

This study focused on estimating the prevalence and evaluating the geospatial distribution of bovine cysticercosis in the state of Mato Grosso, Brazil. To this, we used data of 6,200,497 animals slaughtered during the years of 2013 and 2014, and from 141 municipalities of the state. The prevalence observed for this period was 0.0873% (95% CI 0.0851–0.0897). Regarding the cysticerci detected, the calcified ones were the most frequent (74.43%). The high odds ratios were observed in animals reared in ...

Tópico(s): Parasitic infections in humans and animals

2016 - Elsevier BV | Preventive Veterinary Medicine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Isabel Parizotto Metzdorf, Manoel Sebastião da Costa Lima, Maria de Fátima Cepa Matos, Antônio Francisco de Souza Filho, Rosianne A. de Souza Tsujisaki, Karina Garcia Franco, Julie Teresa Shapiro, Fernando de Almeida Borges,

Leishmaniasis is a "neglected tropical disease" and serious public health issue in Brazil. While dogs are recognized as particularly important reservoirs, recent reports of domestic cats infected with Leishmania sp. in urban areas suggest their participation in the epidemiological chain of the parasite in endemic areas. The aim of this study was to screen domestic cats for Leishmania sp. infection in an area where human and canine visceral leishmaniasis are endemic, followed by the identification ...

Tópico(s): Parasites and Host Interactions

2016 - Elsevier BV | Acta Tropica

Carta Acesso aberto Revisado por pares

Wellington S. Mendes, Antônio Augusto Moura da Silva, Romerito Fonseca Neiva, Nicolle Matos Costa, Maressa Soares de Assis, Priscila Maria Oliveira Vidigal, Maria da Graça Lírio Leite, Elizabeth Salbé Travassos da Rosa, Daniele Barbosa de Almeida Medeiros, Darlene de Brito Simith, Pedro Fernando da Costa Vasconcelos,

To the Editor: Since the etiology of hantavirus cardiopulmonary syndrome (HCPS) was recognized in 1993 in the United States (1), various hantaviruses have been associated with the syndrome in South America (2,3). Depending on the viral genotype involved, hantavirus infection can take a wide variety of forms, from asymptomatic or oligosymptomatic to the classic clinical form (4,5). The first cases of HCPS in Brazil were reported in the state of Sao Paulo in 1993 (6,7). In 2000, an outbreak of HCPS was ...

Tópico(s): Viral Infections and Outbreaks Research

2010 - Centers for Disease Control and Prevention | Emerging infectious diseases

Artigo Brasil Produção Nacional Revisado por pares

Antônio Augusto Fidalgo-Neto, Anael Viana Pinto Alberto, André Gustavo Calvano Bonavita, Rômulo José Soares Bezerra, Felipe Faria Berçot, Renato Matos Lopes, Luiz Anastácio Alves,

... educationThaís Faggioni, Natiele Carla da Silva Ferreira, Renato Matos Lopes, Antonio Augusto Fidalgo-Neto, Vinicius Cotta-de-Almeida, and Luiz Anastacio Alves5 March 2019 | Advances in Physiology Education, Vol. 43, No. 2Pedagogical training profile of basic health sciences faculty in biomedical and related fields at Brazilian public and private higher education institutionsGislaine Alves de Oliveira, Maria Beatriz Cardoso Ferreira, Luciana Neves Nunes, and Maria ...

Tópico(s): Education during COVID-19 pandemic

2014 - American Physical Society | AJP Advances in Physiology Education

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Patricia Balvanera, María Uriarte, Lucía Almeida-Leñero, Alice Altesor, Fabrice DeClerck, Toby Gardner, Jefferson S. Hall, Antonio Lara, Pedro Laterra, Marielos Peña‐Claros, Dalva M. Silva Matos, Adrian Vogl, Luz Piedad Romero‐Duque, Luis Felipe Arreola, Ángela Caro-Borrero, Federico Gallego, Meha Jain, Christian Little, Rafael de Oliveira Xavier, José M. Paruelo, Jesús Emilio Peinado, Lourens Poorter, Nataly Ascarrunz, Francisco Correa, Marcela Bianchessi da Cunha‐Santino, Amabel Paula Hernández-Sánchez, María Vallejos,

Ecosystem services science has developed at a fast rate in Latin America, a region characterized by a high biological and cultural diversity, strong emphasis in foreign investment, and high socioeconomic inequities. Here we conducted the following analyses at the regional and national scales: (1) how and when did the study of ecosystem services arise in each country?, (2) what is our present understanding of ecosystem service supply, delivery to societies, and social and economic values?, (3) what ...

Tópico(s): Economic and Environmental Valuation

2012 - Elsevier BV | Ecosystem Services

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Tatianne Ribeiro, Júlia Teixeira Oliveira, Fernanda Martins de Almeida, Marcelo Antônio Tomaz, Paulo A. Melo, Suelen Adriani Marques, Geanne Matos de Andrade, Ana Maria Blanco Martinez,

Preventing damage caused by nerve degeneration is a great challenge. There is a growing body of evidence implicating extracellular nucleotides and their P2 receptors in many pathophysiological mechanisms. In this work we aimed to investigate the effects of the administration of Brilliant Blue G (BBG) and Pyridoxalphosphate-6-azophenyl-2', 4'- disulphonic acid (PPADS), P2X7 and P2 non-selective receptor antagonists, respectively, on sciatic nerve regeneration. Four groups of mice that underwent nerve ...

Tópico(s): Spinal Cord Injury Research

2017 - Elsevier BV | Brain Research

Artigo Brasil Produção Nacional Revisado por pares

Zina Maria Almeida de Azevedo, Daniella Campelo Batalha Cox Moore, Flavia Aparecida Alves de Matos, Vânia Matos Fonseca, Maria Virgínia Marques Peixoto, Maria Ignez C. Gaspar−Elsas, Erika Santinoni, Luiz Antônio dos Anjos, Eloane Gonçalves Ramos,

Currently, there are no clinical or laboratory parameters that can be used efficiently to predict the prognosis of critically ill patients, but in some situations, raw bioelectrical impedance parameters have been shown to be useful. The purpose of this study was to investigate the behavior of reactance and resistance in the severity of the critically ill pediatric patient.We prospectively analyzed bioelectrical impedance in a sample of 332 critically ill pediatric patients submitted to mechanical ...

Tópico(s): Hemodynamic Monitoring and Therapy

2013 - Elsevier BV | Clinical Nutrition

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Milena Estorniolo,

Dada a relevância das questões que começaram a surgir com a multiplicação dos projetos de apoio para os povos indígenas com os mais diversos enfoques temáticos -desde a gestão territorial e ambiental até questões de gênero, gestão administrativa, sustentabilidade econômica e valorização cultural -as iniciativas desses dois GTs tiveram a intenção

Tópico(s): Indigenous Health and Education

2012 - UNIVERSIDADE DE SÃO PAULO | Revista de Antropologia

Artigo Brasil Produção Nacional Revisado por pares

Luzia Kalyne Almeida Moreira Leal, Ludmila Araújo Rodrigues Lima, Pedro Éverson Alexandre de Aquino, João Antônio Costa de Sousa, Carlos Vinicius Jataí Gadelha, Iana Bantim Felício Calou, Maria Janice Pereira Lopes, Francisco Arnaldo Viana Lima, Kelly Rose Tavares Neves, Geanne Matos de Andrade, Glauce Socorro de Barros Viana,

Vitamin D (VD3, cholecalciferol), besides its role on bone calcium homeostasis, has also been shown to present anti-inflammatory actions. The objectives of the present work were to further extend these findings, focusing onVD3action mechanisms at the molecular level and onits central and peripheral effects. For that, VD3 antinociceptive and mainly anti-inflammatory activities were evaluated by acute models of nociception (formalin test) and inflammation (carrageenan-induced paw edema), in mice pretreated ...

Tópico(s): Stress Responses and Cortisol

2020 - Elsevier BV | European Journal of Pharmacology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Igor Larchert Mota, Antônio Carlos Sobral Sousa, Maria Luíza Dória Almeida, Enaldo Vieira de Melo, Eduardo José Pereira Ferreira, José Barreto Neto, Carlos José Oliveira de Matos, Caio José Coutinho Leal Telino, Maria Júlia Silveira Souto, Joselina Luzia Menezes Oliveira,

Systemic inflammation is the pathophysiological link between coronary artery disease (CAD) and COPD. However, the influence of subclinical COPD on patients with suspected or diagnosed CAD is largely unknown. Thus, this study was designed to evaluate the degree of coronary involvement in patients with COPD and suspected or confirmed CAD.In this cross-sectional study, carried out between March 2015 and June 2017, 210 outpatients with suspected or confirmed CAD were examined by both spirometry and coronary ...

Tópico(s): Pulmonary Hypertension Research and Treatments

2018 - Dove Medical Press | International Journal of COPD

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Rosa Estela Gazeta, Ana Paula Antunes Pascalicchio Bertozzi, Rita de Cássia de Aguirre Bernardes Dezena, Andrea Cristina Botelho Silva, Thamirys Cosmo Gillo Fajardo, Daniel Thomé Catalan, Maria de Fátima Valente Rizzo, Antônio Fernandes Moron, Antoni Soriano‐Arandes, Nuria Sánchez Clemente, Tania Quintella, Dora Fix Ventura, Francisco Max Damico, Valtenice de Cássia Rodrigues de Matos França, Juliana Paula Gomes de Almeida, Ana Laura de Sene Amâncio Zara, Lucas Castro Pires, Cohort Zika vírus Jundiaí, Saulo Duarte Passos,

Congenital Zika virus (ZIKV) infection may present with a broad spectrum of clinical manifestations. Some sequelae, particularly neurodevelopmental problems, may have a later onset. We conducted a prospective cohort study of 799 high-risk pregnant women who were followed up until delivery. Eighty-three women and/or newborns were considered ZIKV exposed and/or infected. Laboratory diagnosis was made by polymerase chain reaction in the pregnant mothers and their respective newborns, as well as Dengue ...

Tópico(s): Viral Infections and Vectors

2021 - Multidisciplinary Digital Publishing Institute | Viruses

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maurício Naoto Saheki, Marcelo Rosandiski Lyra, Sandro Javier Bedoya-Pacheco, Liliane de Fátima Antônio, Maria Inês Fernandes Pimentel, Mariza de Matos Salgueiro, Érica de Camargo Ferreira e Vasconcellos, Sônia Regina Lambert Passos, Ginelza Peres Lima dos Santos, Madelon Novato Ribeiro, Aline Fagundes, Maria de Fátima Madeira, Eliame Mouta‐Confort, Mauro Célio de Almeida Marzochi, Cláudia Maria Valete‐Rosalino, Armando de Oliveira Schubach,

Background Although high dose of antimony is the mainstay for treatment of American cutaneous leishmaniasis (ACL), ongoing major concerns remain over its toxicity. Whether or not low dose antimony regimens provide non-inferior effectiveness and lower toxicity has long been a question of dispute. Methods A single-blind, non-inferiority, randomized controlled trial was conducted comparing high dose with low dose of antimony in subjects with ACL treated at a referral center in Rio de Janeiro, an endemic ...

Tópico(s): Research on Leishmaniasis Studies

2017 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Pricilla de Almeida Moreira, Sheila Maria Alvim Matos, Francisco José Gondim Pitanga, Luana Giatti, Sandhi Maria Barreto, Rosane Härter Griep, Maria da Conceição Chagas de Almeida, Carlos Antônio de Souza Teles Santos,

This study aimed to verify the association between Sedentary Behavior (SB) and performance on cognitive function tests in middle-aged and elderly adults.

Tópico(s): Nutritional Studies and Diet

2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Thiago José Matos Rocha, Maria do Carmo Alves de Lima, Anekécia Lauro da Silva, Jamerson Ferreira de Oliveira, Allana Lemos Andrade Gouveia, Vinícius Barros Ribeiro da Silva, Antônio Sérgio Alves de Almeida Júnior, Fábio André Brayner, Pablo Ramon Gualberto Cardoso, Marina da Rocha Pitta-Galdino, Ivan da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Luiz Carlos Alves, Maíra Galdino da Rocha Pitta,

Schistosomiasis is an infectious parasitic disease caused by trematodes of the genus Schistosoma, which threatens at least 258 million people worldwide and its control is dependent on a single drug, praziquantel. The aim of this study was to evaluate the anti-Schistosoma mansoni activity in vitro of novel imidazolidine derivatives.We synthesized two novel imidazolidine derivatives: (LPSF/PTS10) (Z)-1-(2-chloro-6-fluorobenzyl)-4-(4-dimethylaminobenzylidene)-5-thioxoimidazolidin-2-one and (LPSF/PTS23) ( ...

Tópico(s): Synthesis and biological activity

2017 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo