Robert Nowell, Hala Jaber, Victoria McKee, Anthony Burgess, Barbara Hall, Robert Silver, Mike Graham, Robert Dawson Scott, Tony Hetherigton, Michelene Wandor, Sian Frances, Mary Dowey, John Davison, Jon Swain, John Peter, Malcolm Bardbury, Catherine Steven, Mark Reason, Norman MacRae, Brian Heap, Princess Royal, John Diamond, Neville Hodgkinson Medical Correspondent, Graham Rose, Roy Porter, Norman Howell, Diana Wright Personal Finance Editor, Carolyn Hart, Sally Payne, Linda Taylor, Charles Howe, Geoffrey Heptonstall, Freya Williams, Lynn Greenwood, Marten Julian, Mike Brearley, John O'Byrne, (Mrs) Pat Marston, Cal McCrystal, Mark Ellis, Mark Hosenball, Edward Welsh, Carol Sarler, Dave Webster, Caroline St John-Brooks, Geordie Greig, Patrick Stoddart, Susan Marling, Robert Sandall, Lis Leigh, David Brierley, Irwin Stelzer, Peter Godwin, Mark Ottaway, Geordie Greig Arts Correspondent, Allan Massie, Cliff Temple, Jane Bird, Robert Gore-Langton, Maria Laura Avignolo, Terence Roth, Egon Ronay, Sheila Sharp, Hugh Canning, Margarette Driscoll, David Cairns, Norman Harris, Julia Neuberger, Geoff Whitten, George Perry, Sue Mott, Rex Gooch, Robin Marlar, Charlotte Atkins, Sir Roy Strong, Paul Golding, Bernard Cafferty, M Dowsett, Jon Freeman, Stuart Wavell, Paul Donovan, Janette Marshall, Ian Birrell John Davison, Tim Ross, Amit Roy, Jeff Randall, Jonathan Sale, Mark Ackerman, James Adams, Paul Driver, Boris Schapiro, C Mitchell, David Hughes, Austin MacCurtain, David Leppard, Gerald Hartup, Peter Fisher Chairman, Warren Stutely, C Dicker, Joan Forman, Rufus Olins, Elizabeth Grice, Michael Durham, John Hopkins, Brian Walden, Geoffrey Moorhouse, Mary Sue Davis, John Powell, Peter Wilsher, Gill Charlton, Gareth David, F W Millar, Stephen Pile, Brian Masters, Cheryl Taylor, Marie Colvin, Craig Brown, Diana Wright, Andrew Lorenz Industrial Editor, Kenneth Branagh, Stephen Jones, Brian Deer, Meriel McCooey, Norman Lebrecht, Martin Searby, Bob Rodwell, Safa Haeri, Dilys Powell, Edmund Hall, Rita Lewis, Alison Beckett, Tony Rocca, David Selbourne, Roger Bootle, Richard Woods, Caroline McGhie, Peter Johnson, Mira Bar-Hillel, Marion Hume, Maurice Chittenden, Zoe McKintyre, Joy Melville, Ray Mgadzah, David Hughes Chief Political Correspondent, Tom Adair, Brian MacArthur, David Baldwin, Michael Faraday, Geoffrey Hobbs, D J Taylor, Donald Cameron Watt, Mihir Bose, Stanley Wells Director, Philip Beresford, Godfrey Smith, Charles Oulton, Valerie Eillot, Eden Vale, Brian Glanville, Jeffrey Robinson, Susie Hamilton, Andrew Hogg Nairobi, Chris Dighton, Nadine Meisner, Edward Pearce, Simon Jenkins, Godfrey Golzen, Ronald Gill, Michael Berger, Gareth David Deputy City Editor, Andrew Lorenz, Sue Maw, John Furbisher, Liam Clarke, Duncan Bryson, David Wickers, J H Martin, David Powell, Marina Vaizey, Hugh Pearman, Jeff Randall City Editor, Richard Caseby, Margaret Park, Penny Perrick, Wayne Sleep, Chris Blackhurst, Mark Burton, Clement Freud, Tom Bower, James Adams Defence Correspondent, Hilary Bristow, Muriel Bowen,
... If yor have a number 1 Registratgion for sala plesse Registration Numbers Multiple Classified Advertising Items Sofa ...
1989 - Gale Group | Sunday Times HA GDA
Miguel García‐Guzmán, F. Sala, Salvador Sala, Antonio Campos‐Caro, Manuel Criado,
... 7 Subunit ChimerasMiguel Garcia-Guzman, Francisco Sala, Salvador Sala, Antonio Campos-Caro, and Manuel CriadoCite this: Biochemistry 1994, ...
Tópico(s): Receptor Mechanisms and Signaling
1994 - American Chemical Society | Biochemistry
Giovanni D’Arena, Maria Luigia Vigliotti, Matteo Dell’Olio, Maria Rosaria Villa, Saverio Mantuano, Potito Rosario Scalzulli, Antonio La Sala, Antonio Abbadessa, Lucia Mastrullo, Nicola Cascavilla,
We report four patients (mean age 65 yr; range 40-77 yr) affected by acquired pure red cell aplasia (PRCA) complicating chronic lymphoid disorders and treated with anti-CD20 monoclonal antibody rituximab. Three out of four patients were given packed red cell transfusion. Steroids and recombinant erythropoietin (r-Epo) were also administered as first-line therapy without response. After a mean time of 57 d (range 23-62 d) from PRCA diagnosis, all patients received rituximab at a dosage of 375 mg/m(2)/ ...
Tópico(s): Parvovirus B19 Infection Studies
2008 - Wiley | European Journal Of Haematology
Francisco García‐Río, S. Serrano, A. Dorgham, Rodolfo Álvarez-Sala, Antonio Peña, Jesús Pino, Alvarez-Sala Jl, J. Villamor,
This study analyses the evolution of the bibliometric indicators of productivity and repercussion of European Union (EU) research into the respiratory system during the period from 1987–1998, describing the geographical distribution. Using MedLine, a selection was made of those articles by EU authors published between 1987–1998 in 38 respiratory system journals (classification from the Institute for Scientific Information). The journals, country of origin, number of articles and the relation to socioeconomic ...
Tópico(s): scientometrics and bibliometrics research
2001 - European Respiratory Society | European Respiratory Journal
Giulia De Falco, Luigi Bagella, Pier Paolo Claudio, Antonio De Luca, Yan Fu, Bruno Calabretta, Arturo Sala, Antonio Giordano,
B-Myb is a transcription factor belonging to the myb family, whose activity has been associated with augmented DNA synthesis and cell cycle progression. We showed recently that B-Myb autoregulates its own expression through promoter transactivation. We report in this study that CDK9, the cyclin T associated kinase, which phosphorylates and activates RNA-Polymerase II, suppresses B-Myb autoregulation through direct interaction with the carboxyl-terminus of the B-Myb protein. Down-regulation of the ...
Tópico(s): Cell death mechanisms and regulation
2000 - Springer Nature | Oncogene
F. García Río, Rodolfo Álvarez-Sala, Antonio Peña, Soledad Serrano Peña, J.M. Pino García, J. Villamor León, M. Antonia Gómez Mendieta, Alvarez-Sala Jl,
En los últimos años, el área del sistema respiratorio ha adquirido gran relevancia clínica por la prevalencia de sus enfermedades y por los recursos sanitarios que consume. Los objetivos de este trabajo fueron analizar la evolución de la producción y repercusión de la actividad científica española en el área de sistema respiratorio durante el período 1987-1998 y valorar la participación de las distintas comunidades autónomas. Se seleccionaron los artículos publicados durante el período 1987-1998 ...
Tópico(s): Delphi Technique in Research
2000 - Elsevier BV | Medicina Clínica
Ricardo Borges, F. Sala, Antonio G. Garcı́a,
Catecholamine release from perfused cat adrenal glands has been continuously monitored by on-line connection of the perfusion fluid emanating from the gland to an electrochemical detector. This method allowed: the recording of basal levels and fluctuations of catecholamine release with good reliability; the study of the release of catecholamines in response to even submicromolar concentrations of nicotine or acetylcholine and 3 mM increments of the K+ concentration, perfused in pulses of a few seconds, ...
Tópico(s): Ion channel regulation and function
1986 - Elsevier BV | Journal of Neuroscience Methods
Luigi Casella, Enrico Monzani, Raffaella Roncone, Stefania Nicolis, Alberto Sala, Antonio De Riso,
The peroxidase-catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide has been studied in detail using the enzymes lactoperoxidase (LPO) from bovine milk and horseradish peroxidase (HRP). The results indicate the existence of two competing pathways, in which the nitrating species is either nitrogen dioxide or peroxynitrite. The first pathway involves one-electron oxidation of nitrite by the classical peroxidase intermediates compound I and compound II, whereas in the second pathway ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2002 - National Institute of Environmental Health Sciences | Environmental Health Perspectives
Roberto Verro, Maura Calliera, Guido Maffioli, Domenica Auteri, Serenella Sala, Antonio Finizio, Marco Vighi,
A methodology to develop a GIS-based system for the surface water risk assessment of agricultural chemicals is described. It is based on the integration of relational and spatial databases, GIS incorporating raster and vector, mass balance models, and pesticide risks indicators. Surface water pollution was modeled by taking into account two main processes: the load due to drift and the load due to a rainfall-runoff event. The former is immediately consequent to pesticide application; the second ...
Tópico(s): Hydrology and Watershed Management Studies
2002 - American Chemical Society | Environmental Science & Technology
José Luís Oliva, Dolores Pérez‐Sala, Antonio Castrillo, Natalia J. Martinez, F. Javier Cañada, Lisardo Boscá, José M. Rojas,
The cyclopentenone 15-deoxy-Δ 12,14 -prostaglandin J 2 (15d-PGJ 2 ) induces cell proliferation and mitogen-activated protein kinase activation. Here, we describe that these effects are mediated by 15d-PGJ 2 -elicited H-Ras activation. We demonstrate that this pathway is specific for H-Ras through the formation of a covalent adduct of 15d-PGJ 2 with Cys-184 of H-Ras, but not with N-Ras or K-Ras. Mutation of C184 inhibited H-Ras modification and activation by 15d-PGJ 2 , whereas serum-elicited stimulation ...
Tópico(s): NF-κB Signaling Pathways
2003 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Jorge Leonardo Sanchez, Juan Borrero, Beatriz Gómez‐Sala, Antonio Basanta, Carmen Herranz, Luis M. Cintas, Pablo E. Hernández,
ABSTRACT Hiracin JM79 (HirJM79), a Sec-dependent bacteriocin produced by Enterococcus hirae DCH5, was cloned and produced in Lactococcus lactis , Lactobacillus sakei , Enterococcus faecium , Enterococcus faecalis , and Pichia pastoris . For heterologous production of HirJM79 in lactic acid bacteria (LAB), the HirJM79 structural gene ( hirJM79 ), with or without the HirJM79 immunity gene ( hiriJM79 ), was cloned into the plasmid pMG36c under the control of the constitutive promoter P 32 and into the plasmid pNZ8048 under ...
Tópico(s): Biochemical and Structural Characterization
2008 - American Society for Microbiology | Applied and Environmental Microbiology
Gabriel Capellá, Guillem Pera, Núria Sala, Antonio Agudo, F. Rico, G. Del Giudicce, Mario Plebani, Domenico Palli, H. Boeing, H. Bas Bueno-de-Mesquita, Fátima Carneiro, Franco Berrino, P. Vineis, Rosario Tumino, Salvatore Panico, G. Berglund, Henrik Simán, Olof Nyrén, Göran Hallmans, Carmen Martínez, M. Dorronsoro, Aurelio Barricarte, Carmen Navarro, J. R Quiros, Naomi E. Allen, Timothy J. Key, Sheila Bingham, Carlos Caldas, Jakob Linseisen, Gabriele Nagel, Kim Overvad, Anne Tjønneland, Hendriek C. Boshuizen, P. H. M. Peeters, M.E. Numans, F. Clavel-Chapelon, Antonia Trichopoulou, Eiliv Lund, Mazda Jenab, Rudolf Kaaks, Elio Ríboli, Carlos A. González,
The contribution of genetic variation in DNA repair genes to gastric cancer (GC) risk remains essentially unknown. The aim of this study was to explore the relative contribution of DNA repair gene polymorphisms to GC risk and severe chronic atrophic gastritis (SCAG). Method A nested case control study within the EPIC cohort was performed including 246 gastric adenocarcinomas and 1175 matched controls. Controls with SCAG (n = 91), as defined by low pepsinogen A (PGA) levels, and controls with no SCAG (n = ...
Tópico(s): RNA modifications and cancer
2008 - Oxford University Press | International Journal of Epidemiology
J. Bart A. Crusius, Federico Canzian, Gabriel Capellá, A. S. Peña, Guillem Pera, Núria Sala, Antonio Agudo, F. Rico, Giuseppe Del Giudice, Domenico Palli, Mario Plebani, Heiner Boeing, H. B. Bueno-de-Mesquita, Fátima Carneiro, Valeria Pala, Vicki Save, Paolo Vineis, Rosario Tumino, Salvatore Panico, G Berglund, Jonas Manjer, Roger Stenling, G. Hallmans, C. Martínez, M. Dorronsoro, Aurelio Barricarte, Carmen Navarro, J.R. Quirós, N. E. Allen, Timothy J. Key, S. Binghan, Carlos Caldas, Jakob Linseisen, R. Kaaks, Kim Overvad, Anne Tjønneland, F.C. Büchner, P. H. Peeters, Mattijs E. Numans, Françoise Clavel‐Chapelon, Antonia Trichopoulou, Eiliv Lund, Mazda Jenab, Sabina Rinaldi, Pietro Ferrari, Elio Ríboli, Carlos A. González,
BackgroundThe relative contribution to gastric cancer (GC) risk of variants in genes that determine the inflammatory response remains mostly unknown and results from genotyping studies are inconsistent.Patients and methodsA nested case–control study within the prospective European Prospective Investigation into Cancer and Nutrition cohort was carried out, including 248 gastric adenocarcinomas and 770 matched controls. Twenty common polymorphisms at cytokine genes [interleukin (IL)1A, IL1B, IL1RN, IL4, ...
Tópico(s): Genetic factors in colorectal cancer
2008 - Elsevier BV | Annals of Oncology
Isabel Gómez‐Monterrey, Pietro Campiglia, Alfonso Carotenuto, Daniela Califano, Claudio Pisano, Loredana Vesci, Teresa Lama, Alessia Bertamino, Marina Sala, Antonio Bosco, Paolo Grieco, Ettore Novellino,
A series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives were prepared using an easy synthetic route via condensation of the 3-amino-3-(ethoxycarbonyl)-2,3-dihydrothieno[2,3-b]naphtho-4,9-dione system and amino acids followed by intramolecular lactamization. Amino acids containing alkyl and aryl, linear and cyclic, polar and apolar, and basic and acid residues were incorporated. Evaluation of these analogues against the MCF-7 human ...
Tópico(s): Synthesis and Biological Evaluation
2007 - American Chemical Society | Journal of Medicinal Chemistry
Dan J. Stein, Jannicke Igland, Mazda Jenab, Åse Fredriksen, Klaus Meyer, Simone J.P.M. Eussen, Håkon K. Gjessing, Per Magne Ueland, Guillem Pera, Núria Sala, Antonio Agudo, Gabriel Capellá, Giuseppe Del Giudice, Domenico Palli, Heiner Boeing, Cornelia Weikert, H. Bas Bueno‐de‐Mesquita, Fátima Carneiro, Valeria Pala, Paolo Vineis, Rosario Tumino, Salvatore Panico, Göran Berglund, Jonas Manjer, Roger Stenling, Göran Hallmans, Carmen Martı́nez, Miren Dorronsoro, Aurelio Barricarte, Carmen Navarro, J. Ramón Quirós, Naomi E. Allen, Timothy J. Key, Sheila Bingham, Jakob Linseisen, Rudolf Kaaks, Kim Overvad, Anne Tjønneland, Frederike L. Büchner, Petra H. Peeters, Mattijs E. Numans, Françoise Clavel‐Chapelon, Marie‐Christine Boutron‐Ruault, Antonia Trichopoulou, Eiliv Lund, Nadia Slimani, Pietro Ferrari, Elio Ríboli, Carlos A. González,
Abstract Previous studies have shown inconsistent associations of folate intake and polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene with gastric cancer risk. Our nested case-control study within the European Prospective Investigation into Cancer and Nutrition cohort is the first prospective study of blood folate levels and gastric cancer. Gastric cancer cases (n = 247) and controls (n = 631) were matched for study center, age, sex, and time of blood donation. Two common single nucleotide ...
Tópico(s): Gastroesophageal reflux and treatments
2007 - American Association for Cancer Research | Cancer Epidemiology Biomarkers & Prevention
Dalia Aminoff, Edoardo La Sala, Antonio Zaccara,
Several studies addressed the long-term follow-up of anorectal anomalies (ARM) in relation to clinical issues (eg, continence) and quality of life. However, most of these studies are based upon questionnaires designed by physicians and/or health-care professionals, which may be sources of bias.To investigate whether parents of children (patients themselves or older children or adults) who were born with ARM had the perception that they received appropriate care and follow-up, a survey was carried out ...
Tópico(s): Anorectal Disease Treatments and Outcomes
2006 - Elsevier BV | Journal of Pediatric Surgery
Maximino Redondo, Rafael Fúnez, F. Medina-Cano, Isabel Rodrigo, Mercedes Acebal, Teresa Téllez, M. Roldán, María Luisa Hortas, Ana Bellinvia, Teresa Pereda, Laia Domingo, María Morales-Suarez Varela, María Sala, Antonio Rueda,
The aim of this study was to measure the biological characteristics involved in tumorigenesis and the progression of breast cancer in symptomatic and screen-detected carcinomas to identify possible differences. For this purpose, we evaluated clinical-pathological parameters and proliferative and apoptotic activities in a series of 130 symptomatic and 161 screen-detected tumors. After adjustment for the smaller size of the screen-detected carcinomas compared with symptomatic cancers, those detected ...
Tópico(s): Lung Cancer Treatments and Mutations
2012 - BioMed Central | BMC Cancer
Roberto Rizzi, Elisa Di Pasquale, Paola Portararo, Roberto Papait, Paola Cattaneo, Michael V.G. Latronico, Claudia Altomare, Luca Sala, Antonio Zaza, Emilio Hirsch, Luigi Naldini, Gianluigi Condorelli, Claudia Bearzi,
Adult mammalian cells can be reprogrammed to a pluripotent state by forcing the expression of a few embryonic transcription factors. The resulting induced pluripotent stem (iPS) cells can differentiate into cells of all three germ layers. It is well known that post-natal cardiomyocytes (CMs) lack the capacity to proliferate. Here, we report that neonatal CMs can be reprogrammed to generate iPS cells that express embryonic-specific markers and feature gene-expression profiles similar to those of mouse ...
Tópico(s): CRISPR and Genetic Engineering
2012 - Springer Nature | Cell Death and Differentiation
Arturo Sala, Antonio De Luca, Antonio Giordano, C Peschle,
It was recently reported that B-MYB can overcome p107-induced growth arrest. Here we show that B-MYB autoregulation of its own transcription is specifically suppressed by p107 and transient transfection assays with p107 deletion constructs determined that the carboxyl terminus of the protein, containing the major pocket region, was associated with inhibition of B-MYB-dependent transactivation. Consistent with these results, co-immunoprecipitation studies showed that p107 interacted in vivo with ...
Tópico(s): Ubiquitin and proteasome pathways
1996 - Elsevier BV | Journal of Biological Chemistry
Jaume Marrugat, Maria García-Gil, Roberto Elosúa, Elena Aldasoro, María José Tormo, Óscar Zurriaga, Fernando Arós, Rafael Masiá, Ginés Sanz, Vicente Valle, Esteban López de Sá, Joan Sala, Antonio Segura, Catalina Rubert, C. Moreno, Adolfo Cabadés, Lluís Molina Balaguer, José Luís López-Sendón, Miguel Gil,
Tópico(s): Healthcare Systems and Public Health
2004 - Elsevier BV | The American Journal of Cardiology
Ángela Cepero Calvete, J. Dios Berná Mestre, José Manuel Rodríguez González, Elena Sáez Martinez, Begoña Torregrosa Sala, Antonio Ríos,
To study acoustic radiation force impulse (ARFI) imaging as a new quantitative and noninvasive tool for evaluating thyroid nodules and to compare ARFI imaging with other tools for studying thyroid nodules: sonography, real-time elastography, and fine-needle aspiration biopsy.We conducted a prospective study from June 2011 to June 2012, which analyzed 157 thyroid nodules (129 benign and 28 malignant) using the ARFI technique and a 9-MHz probe. Shear wave velocities (SWVs) were obtained while the patients ...
Tópico(s): Ultrasound Imaging and Elastography
2014 - Wiley | Journal of Ultrasound in Medicine
Miguel García‐Guzmán, F. Sala, Salvador Sala, Antonio Campos‐Caro, Walter Stühmer, Luis M. Gutiérrez, Manuel Criado,
Abstract Chromaffin cells from the bovine adrenal medulla express α‐bungarotoxin‐sensitive acetylcholine receptors whose subunit composition is unknown. Northern blot analysis showed that the α7 subunit, a main component of these α‐bungarotoxin‐sensitive acetylcholine receptors in avian and rat brain, is expressed in chromaffin cells. The cDNA of this bovine α7 subunit was cloned by polymerase chain reaction amplification of adrenal medulla RNA for detailed characterization of structure and function. ...
Tópico(s): Insect and Pesticide Research
1995 - Wiley | European Journal of Neuroscience
Sabatino Cuomo, Maria Della Sala, Antonio Novità,
In coarse-grained, unsaturated soils, heavy rainstorms may cause either shallow landslides or superficial soil erosion. The triggering of both of these phenomena is related to infiltration, runoff and overland flow, which are key processes requiring investigation. In particular, the quantitative estimates of the sediment yield at the outlet of mountain basins requires suitable physically based modelling. In this paper, the available approaches to soil erosion analysis are first reviewed, and the ...
Tópico(s): Landslides and related hazards
2015 - Elsevier BV | Geomorphology
Diabetes mellitus--whether driven by insulin deficiency or insulin resistance--causes major alterations in muscle metabolism. These alterations have an impact on nutrient handling, including the metabolism of glucose, lipids, and amino acids, and also on muscle mass and strength. However, the ways in which the distinct forms of diabetes affect muscle mass differ greatly. The most common forms of diabetes mellitus are type 1 and type 2. Thus, whereas type 1 diabetic subjects without insulin treatment ...
Tópico(s): Diet and metabolism studies
2015 - Springer Nature | Cellular and Molecular Life Sciences
Francesco Prattichizzo, Valeria De Nigris, Lucia La Sala, Antonio Domenico Procopio, Fabiola Olivieri, Antonio Ceriello,
Aging is a complex phenomenon driven by a variety of molecular alterations. A relevant feature of aging is chronic low‐grade inflammation, termed “inflammaging.” In type 2 diabetes mellitus (T2DM), many elements of aging appear earlier or are overrepresented, including consistent inflammaging. T2DM patients have an increased death rate, associated with an incremented inflammatory score. The source of this inflammation is debated. Recently, the senescence‐associated secretory phenotype (SASP) has been ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2016 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
Leticia Sala, Antonio Bascones Martínez, A. Carrillo de Albornoz,
Tópico(s): Orthodontics and Dentofacial Orthopedics
2016 - Springer Nature | Clinical Oral Investigations
Adriana Ariza, Cristobalina Mayorga, María Salas, Inmaculada Doña, Ángela Martín‐Serrano Ortiz, Ezequiel Pérez‐Inestrosa, Dolores Pérez‐Sala, Antonio Guzman, María I. Montañez, Marı́a José Torres,
Abstract The optimal recognition of penicillin determinants, including amoxicillin (AX), by specific IgE antibodies is widely believed to require covalent binding to a carrier molecule. The nature of the carrier and its contribution to the antigenic determinant is not well known. Here we aimed to evaluate the specific-IgE recognition of different AX-derived structures. We studied patients with immediate hypersensitivity reactions to AX, classified as selective or cross-reactors to penicillins. Competitive ...
Tópico(s): Food Allergy and Anaphylaxis Research
2016 - Nature Portfolio | Scientific Reports
Matteo Gastaldi, Elisabetta Zardini, Rosaria Leante, Maddalena Ruggieri, Gianna Costa, Eleonora Cocco, Giovanna De Luca, Ivana Cataldo, Tiziana Biagioli, Clara Ballerini, Massimiliano Castellazzi, Enrico Fainardi, P Pettini, Mauro Zaffaroni, Debora Giunti, Elisabetta Capello, Gaetano Bernardi, Emilio Ciusani, Claudia Giannotta, Eduardo Nobile‐Orazio, Elena Bazzigaluppi, Gabriella Passerini, Roberta Bedin, Patrizia Sola, Rinaldo Brivio, Guido Cavaletti, Arianna Sala, Antonio Bertolotto, Gaetano Desina, Maurizio Leone, Sara Mariotto, Sérgio Ferrari, Andreina Paternoster, Davide Giavarina, Francesco Lolli, Diego Franciotta,
This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroinflammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2017 - Springer Science+Business Media | Neurological Sciences
Francesco Prattichizzo, Valeria De Nigris, Stefano Micheloni, Lucia La Sala, Antonio Ceriello,
Recent clinical trials have demonstrated a strong cardiovascular (CV) protective effect of sodium/glucose cotransporter (SGLT) 2 inhibitors, a recently introduced class of hypoglycaemic agents. The improvement in glycated haemoglobin and other conventional risk factors explains only a portion of the observed reduction in CV risk. A relevant feature of SGLT2‐inhibitor‐treated diabetic patients is the increase in circulating levels of ketone bodies, which has been proposed to mediate part of the beneficial ...
Tópico(s): Diet and metabolism studies
2018 - Wiley | Diabetes Obesity and Metabolism
Claudio Sassanelli, Giuditta Pezzotta, Fabiana Pirola, Roberto Sala, Antonio Margarito, Mariangela Lazoi, Angelo Corallo, Mónica Rossi, Sergio Terzi,
Nowadays, product service systems (PSSs) and smart products are surging in the market and acquiring a strategic role for companies' survival. Manufacturers, compelled towards the transformation process into PSS providers, have to face the challenge of building up knowledge for successfully providing such complex solutions, also resorting to the help of more effective IT systems and tools. The need to adopt a collaborative design platform is starting to be raised also in the PSS context, since companies ...
Tópico(s): Digital Transformation in Industry
2018 - Inderscience Publishers | International Journal of Product Lifecycle Management