Robert Nowell, Hala Jaber, Victoria McKee, Anthony Burgess, Barbara Hall, Robert Silver, Mike Graham, Robert Dawson Scott, Tony Hetherigton, Michelene Wandor, Sian Frances, Mary Dowey, John Davison, Jon Swain, John Peter, Malcolm Bardbury, Catherine Steven, Mark Reason, Norman MacRae, Brian Heap, Princess Royal, John Diamond, Neville Hodgkinson Medical Correspondent, Graham Rose, Roy Porter, Norman Howell, Diana Wright Personal Finance Editor, Carolyn Hart, Sally Payne, Linda Taylor, Charles Howe, Geoffrey Heptonstall, Freya Williams, Lynn Greenwood, Marten Julian, Mike Brearley, John O'Byrne, (Mrs) Pat Marston, Cal McCrystal, Mark Ellis, Mark Hosenball, Edward Welsh, Carol Sarler, Dave Webster, Caroline St John-Brooks, Geordie Greig, Patrick Stoddart, Susan Marling, Robert Sandall, Lis Leigh, David Brierley, Irwin Stelzer, Peter Godwin, Mark Ottaway, Geordie Greig Arts Correspondent, Allan Massie, Cliff Temple, Jane Bird, Robert Gore-Langton, Maria Laura Avignolo, Terence Roth, Egon Ronay, Sheila Sharp, Hugh Canning, Margarette Driscoll, David Cairns, Norman Harris, Julia Neuberger, Geoff Whitten, George Perry, Sue Mott, Rex Gooch, Robin Marlar, Charlotte Atkins, Sir Roy Strong, Paul Golding, Bernard Cafferty, M Dowsett, Jon Freeman, Stuart Wavell, Paul Donovan, Janette Marshall, Ian Birrell John Davison, Tim Ross, Amit Roy, Jeff Randall, Jonathan Sale, Mark Ackerman, James Adams, Paul Driver, Boris Schapiro, C Mitchell, David Hughes, Austin MacCurtain, David Leppard, Gerald Hartup, Peter Fisher Chairman, Warren Stutely, C Dicker, Joan Forman, Rufus Olins, Elizabeth Grice, Michael Durham, John Hopkins, Brian Walden, Geoffrey Moorhouse, Mary Sue Davis, John Powell, Peter Wilsher, Gill Charlton, Gareth David, F W Millar, Stephen Pile, Brian Masters, Cheryl Taylor, Marie Colvin, Craig Brown, Diana Wright, Andrew Lorenz Industrial Editor, Kenneth Branagh, Stephen Jones, Brian Deer, Meriel McCooey, Norman Lebrecht, Martin Searby, Bob Rodwell, Safa Haeri, Dilys Powell, Edmund Hall, Rita Lewis, Alison Beckett, Tony Rocca, David Selbourne, Roger Bootle, Richard Woods, Caroline McGhie, Peter Johnson, Mira Bar-Hillel, Marion Hume, Maurice Chittenden, Zoe McKintyre, Joy Melville, Ray Mgadzah, David Hughes Chief Political Correspondent, Tom Adair, Brian MacArthur, David Baldwin, Michael Faraday, Geoffrey Hobbs, D J Taylor, Donald Cameron Watt, Mihir Bose, Stanley Wells Director, Philip Beresford, Godfrey Smith, Charles Oulton, Valerie Eillot, Eden Vale, Brian Glanville, Jeffrey Robinson, Susie Hamilton, Andrew Hogg Nairobi, Chris Dighton, Nadine Meisner, Edward Pearce, Simon Jenkins, Godfrey Golzen, Ronald Gill, Michael Berger, Gareth David Deputy City Editor, Andrew Lorenz, Sue Maw, John Furbisher, Liam Clarke, Duncan Bryson, David Wickers, J H Martin, David Powell, Marina Vaizey, Hugh Pearman, Jeff Randall City Editor, Richard Caseby, Margaret Park, Penny Perrick, Wayne Sleep, Chris Blackhurst, Mark Burton, Clement Freud, Tom Bower, James Adams Defence Correspondent, Hilary Bristow, Muriel Bowen,
... If yor have a number 1 Registratgion for sala plesse Registration Numbers Multiple Classified Advertising Items Sofa ...
1989 - Gale Group | Sunday Times HA GDA
Miguel García‐Guzmán, F. Sala, Salvador Sala, Antonio Campos‐Caro, Manuel Criado,
... 7 Subunit ChimerasMiguel Garcia-Guzman, Francisco Sala, Salvador Sala, Antonio Campos-Caro, and Manuel CriadoCite this: Biochemistry 1994, ...
Tópico(s): Receptor Mechanisms and Signaling
1994 - American Chemical Society | Biochemistry
Giovanni D’Arena, Maria Luigia Vigliotti, Matteo Dell’Olio, Maria Rosaria Villa, Saverio Mantuano, Potito Rosario Scalzulli, Antonio La Sala, Antonio Abbadessa, Lucia Mastrullo, Nicola Cascavilla,
We report four patients (mean age 65 yr; range 40-77 yr) affected by acquired pure red cell aplasia (PRCA) complicating chronic lymphoid disorders and treated with anti-CD20 monoclonal antibody rituximab. Three out of four patients were given packed red cell transfusion. Steroids and recombinant erythropoietin (r-Epo) were also administered as first-line therapy without response. After a mean time of 57 d (range 23-62 d) from PRCA diagnosis, all patients received rituximab at a dosage of 375 mg/m(2)/ ...
Tópico(s): Parvovirus B19 Infection Studies
2008 - Wiley | European Journal Of Haematology
Francisco García‐Río, S. Serrano, A. Dorgham, Rodolfo Álvarez-Sala, Antonio Peña, Jesús Pino, Alvarez-Sala Jl, J. Villamor,
This study analyses the evolution of the bibliometric indicators of productivity and repercussion of European Union (EU) research into the respiratory system during the period from 1987–1998, describing the geographical distribution. Using MedLine, a selection was made of those articles by EU authors published between 1987–1998 in 38 respiratory system journals (classification from the Institute for Scientific Information). The journals, country of origin, number of articles and the relation to socioeconomic ...
Tópico(s): scientometrics and bibliometrics research
2001 - European Respiratory Society | European Respiratory Journal
Giulia De Falco, Luigi Bagella, Pier Paolo Claudio, Antonio De Luca, Yan Fu, Bruno Calabretta, Arturo Sala, Antonio Giordano,
B-Myb is a transcription factor belonging to the myb family, whose activity has been associated with augmented DNA synthesis and cell cycle progression. We showed recently that B-Myb autoregulates its own expression through promoter transactivation. We report in this study that CDK9, the cyclin T associated kinase, which phosphorylates and activates RNA-Polymerase II, suppresses B-Myb autoregulation through direct interaction with the carboxyl-terminus of the B-Myb protein. Down-regulation of the ...
Tópico(s): Cell death mechanisms and regulation
2000 - Springer Nature | Oncogene
F. García Río, Rodolfo Álvarez-Sala, Antonio Peña, Soledad Serrano Peña, J.M. Pino García, J. Villamor León, M. Antonia Gómez Mendieta, Alvarez-Sala Jl,
En los últimos años, el área del sistema respiratorio ha adquirido gran relevancia clínica por la prevalencia de sus enfermedades y por los recursos sanitarios que consume. Los objetivos de este trabajo fueron analizar la evolución de la producción y repercusión de la actividad científica española en el área de sistema respiratorio durante el período 1987-1998 y valorar la participación de las distintas comunidades autónomas. Se seleccionaron los artículos publicados durante el período 1987-1998 ...
Tópico(s): Delphi Technique in Research
2000 - Elsevier BV | Medicina Clínica
Gabriel Capellá, Guillem Pera, Núria Sala, Antonio Agudo, F. Rico, G. Del Giudicce, Mario Plebani, Domenico Palli, H. Boeing, H. Bas Bueno-de-Mesquita, Fátima Carneiro, Franco Berrino, P. Vineis, Rosario Tumino, Salvatore Panico, G. Berglund, Henrik Simán, Olof Nyrén, Göran Hallmans, Carmen Martínez, M. Dorronsoro, Aurelio Barricarte, Carmen Navarro, J. R Quiros, Naomi E. Allen, Timothy J. Key, Sheila Bingham, Carlos Caldas, Jakob Linseisen, Gabriele Nagel, Kim Overvad, Anne Tjønneland, Hendriek C. Boshuizen, P. H. M. Peeters, M.E. Numans, F. Clavel-Chapelon, Antonia Trichopoulou, Eiliv Lund, Mazda Jenab, Rudolf Kaaks, Elio Ríboli, Carlos A. González,
The contribution of genetic variation in DNA repair genes to gastric cancer (GC) risk remains essentially unknown. The aim of this study was to explore the relative contribution of DNA repair gene polymorphisms to GC risk and severe chronic atrophic gastritis (SCAG). Method A nested case control study within the EPIC cohort was performed including 246 gastric adenocarcinomas and 1175 matched controls. Controls with SCAG (n = 91), as defined by low pepsinogen A (PGA) levels, and controls with no SCAG (n = ...
Tópico(s): RNA modifications and cancer
2008 - Oxford University Press | International Journal of Epidemiology
Jorge Leonardo Sanchez, Juan Borrero, Beatriz Gómez‐Sala, Antonio Basanta, Carmen Herranz, Luis M. Cintas, Pablo E. Hernández,
ABSTRACT Hiracin JM79 (HirJM79), a Sec-dependent bacteriocin produced by Enterococcus hirae DCH5, was cloned and produced in Lactococcus lactis , Lactobacillus sakei , Enterococcus faecium , Enterococcus faecalis , and Pichia pastoris . For heterologous production of HirJM79 in lactic acid bacteria (LAB), the HirJM79 structural gene ( hirJM79 ), with or without the HirJM79 immunity gene ( hiriJM79 ), was cloned into the plasmid pMG36c under the control of the constitutive promoter P 32 and into the plasmid pNZ8048 under ...
Tópico(s): Biochemical and Structural Characterization
2008 - American Society for Microbiology | Applied and Environmental Microbiology
J. Bart A. Crusius, Federico Canzian, Gabriel Capellà, A. S. Peña, Guillem Pera, Núria Sala, Antonio Agudo, F. Rico, Giuseppe Del Giudice, Domenico Palli, Mario Plebani, Heiner Boeing, H. B. Bueno-de-Mesquita, Fátima Carneiro, Valeria Pala, Vicki Save, Paolo Vineis, Rosario Tumino, Salvatore Panico, G Berglund, Jonas Manjer, Roger Stenling, G. Hallmans, C. Martínez, M. Dorronsoro, Aurelio Barricarte, Carmen Navarro, J.R. Quirós, N. E. Allen, Timothy J. Key, S. Binghan, Carlos Caldas, Jakob Linseisen, R. Kaaks, Kim Overvad, Anne Tjønneland, F.C. Büchner, P. H. Peeters, Mattijs E. Numans, Françoise Clavel‐Chapelon, Antonia Trichopoulou, Eiliv Lund, Mazda Jenab, Sabina Rinaldi, Pietro Ferrari, Elio Ríboli, Carlos A. González,
BackgroundThe relative contribution to gastric cancer (GC) risk of variants in genes that determine the inflammatory response remains mostly unknown and results from genotyping studies are inconsistent.Patients and methodsA nested case–control study within the prospective European Prospective Investigation into Cancer and Nutrition cohort was carried out, including 248 gastric adenocarcinomas and 770 matched controls. Twenty common polymorphisms at cytokine genes [interleukin (IL)1A, IL1B, IL1RN, IL4, ...
Tópico(s): Genetic factors in colorectal cancer
2008 - Elsevier BV | Annals of Oncology
Federico Benazzo, Daniela Rigamonti, Paolo Bettini, Giuseppe Sala, Antonio Mattia Grande,
Technologies to control and reduce delamination damage in fibre reinforced polymer composites involve the use of fibre optic sensors and self-healing polymers, respectively. While the former technology can monitor the evolution of damage by measuring microscopic variations in the material's strain field, the latter can repair delamination damage by recreating broken interfaces. To evaluate the combination of these technologies, a high-performance epoxy vitrimer was used as the matrix phase of a ...
Tópico(s): Mechanical Behavior of Composites
2022 - Elsevier BV | Composites Part B Engineering
Francesca Della Sala, Antonio Fabozzi, Mario di Gennaro, Stefano Nuzzo, Pooyan Makvandi, Nicola Solimando, Maurizio Pagliuca, Assunta Borzacchiello,
Cancer is the main cause of fatality all over the world with a considerable growth rate. Many biologically active nanoplatforms are exploited for tumor treatment. Of nanodevices, hyaluronic acid (HA)-based systems have shown to be promising candidates for cancer therapy due to their high biocompatibility and cell internalization. Herein, surface functionalization of different nanoparticles (NPs), e.g., organic- and inorganic-based NPs, is highlighted. Subsequently, HA-based nanostructures and their ...
Tópico(s): Nanoplatforms for cancer theranostics
2021 - Wiley | Macromolecular Bioscience
Kadir Günaydın, Aykut Tamer, Halit S. Türkmen, Giuseppe Sala, Antonio Mattia Grande,
Our research investigated the energy absorption characteristics of chiral auxetic lattices filled cylindrical composite tubes subjected to a uniaxial and lateral quasi-static load. The lattice structures were manufactured using a 3D printing technique. Carbon fiber composite tubes without filler material were initially subjected to uniaxial and lateral quasi-static crushing load. The same types of experiment were then performed on chiral lattices and chiral lattices filled composite tubes. For the ...
Tópico(s): Advanced Materials and Mechanics
2021 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Lucia La Sala, Antonio E. Pontiroli,
The goal of diabetes care is to achieve and maintain good glycemic control over time, so as to prevent or delay the development of micro- and macrovascular complications in type 1 (T1D) and type 2 diabetes (T2D). However, numerous barriers hinder the achievement of this goal, first of all the frequent episodes of hypoglycemia typical in patients treated with insulin as T1D patients, or sulphonylureas as T2D patients. The prevention strategy and treatment of hypoglycemia are important for the well- ...
Tópico(s): Pancreatic function and diabetes
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Corrado Campochiaro, Nicola Farina, Alessandro Tomelleri, Roberto Ferrara, Chiara Lazzari, Giacomo De Luca, Alessandra Bulotta, Diego Signorelli, Anna Palmisano, Davide Vignale, Giovanni Peretto, Simone Sala, Antonio Esposito, Marina Chiara Garassino, Vanesa Gregorc, Lorenzo Dagna,
Abstract Objective Research is moving towards a more personalized management of immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI). Our objective was to evaluate the efficacy and safety of tocilizumab in the treatment of these clinical manifestations. Methods A systematic literature review was performed to retrieve data about the use of tocilizumab in the treatment of irAEs. Additionally, data from cancer patients referred to our Immune-related Adverse Event Clinic and treated ...
Tópico(s): Lung Cancer Treatments and Mutations
2021 - Elsevier BV | European Journal of Internal Medicine
Lucia La Sala, Antonio E. Pontiroli,
Obesity is one of the major risk factors for the development of both impaired glucose tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide drives toward an increased rate of cardiovascular morbidity and mortality. Given the estimations of the World Health Organization (WHO) and the recommendation of the Diabetes Prevention Program (DPP), where IGT and diabetes are considered as risk factors for the development of cardiovascular complications and obesity, the development ...
Tópico(s): Pharmacology and Obesity Treatment
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
S. Garavelli, Sara Bruzzaniti, Elena Tagliabue, Dario Di Silvestre, Francesco Prattichizzo, Enza Mozzillo, V. Fattorusso, Lucia La Sala, Antonio Ceriello, Annibale Alessandro Puca, Pierluigi Mauri, Rocky Strollo, Marco Marigliano, Claudio Maffeis, Alessandra Petrelli, Emanuele Bosi, Adriana Franzese, Mario Galgani, Giuseppe Matarese, Paola de Candia,
We aimed to analyse the association between plasma circulating microRNAs (miRNAs) and the immunometabolic profile in children with type 1 diabetes and to identify a composite signature of miRNAs/immunometabolic factors able to predict type 1 diabetes progression.Plasma samples were obtained from children at diagnosis of type 1 diabetes (n = 88) and at 12 (n = 32) and 24 (n = 30) months after disease onset and from healthy control children with similar sex and age distribution (n = 47). We quantified 60 robustly ...
Tópico(s): Phagocytosis and Immune Regulation
2020 - Springer Science+Business Media | Diabetologia
S. Garavelli, Sara Bruzzaniti, Elena Tagliabue, Francesco Prattichizzo, Dario Di Silvestre, Francesco Perna, Lucia La Sala, Antonio Ceriello, Enza Mozzillo, V. Fattorusso, Pierluigi Mauri, Annibale Alessandro Puca, Adriana Franzese, Giuseppe Matarese, Mario Galgani, Paola de Candia,
Immune cell subsets and microRNAs have been independently proposed as type 1 diabetes (T1D) diagnostic and/or prognostic biomarkers. Here, we aimed to analyze the relationships between peripheral blood circulating immune cell subsets, plasmatic microRNAs, and T1D. Blood samples were obtained from both children with T1D at diagnosis and age-sex matched healthy controls. Then, immunophenotype assessed by flow cytometry was coupled with the quantification of 60 plasmatic microRNAs by quantitative RT- ...
Tópico(s): MicroRNA in disease regulation
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Juan José Carreras, Willian E Tapia-Ramirez, Adrian Sala, Antonio José Guillot, Teresa Garrigues, Ana Melero,
Tópico(s): Advanced Drug Delivery Systems
2019 - Springer Science+Business Media | Drug Delivery and Translational Research
Elvira Escribano-Ferrer, Josep Queralt Regué, Xavier Garcia-Sala, Antonio Boix‐Montañés, Rosa M. Lamuela‐Raventós,
Flavonoids, found in almost all fruits and vegetables, belong to a class of plant secondary metabolites with a polyphenolic structure and have properties with health-improving potential. However, few experimental studies on the effects of flavonoids have been carried out in vivo after external application and using pure compounds. Aiming to fill this gap, in this study we tested the topical anti-inflammatory and antiallergic activity of three flavonoids of high purity, naringenin, naringenin chalcone, ...
Tópico(s): Essential Oils and Antimicrobial Activity
2019 - American Chemical Society | Journal of Natural Products
Alessandra De Cesare, Elisabetta Caselli, Alex Lucchi, Claudia Sala, Antonio Parisi, Gerardo Manfreda, Sante Mazzacane,
This study investigated for the first time the decontamination efficacy of a probiotic-based cleaning product containing Bacillus subtilis, Bacillus pumilus, and Bacillus megaterium spores on fresh and reused broiler litters during 3 rearing cycles of 6 wk each. Moreover, the impact of reused litters treated with the cleaning product on the chicken caeca microbiota was assessed at the end of the rearing cycles in comparison to untreated litter. The Bacillus spores provided with the cleaning treatment ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2019 - Elsevier BV | Poultry Science
Francesco Prattichizzo, Lucia La Sala, Antonio Ceriello,
Tópico(s): Metabolism, Diabetes, and Cancer
2019 - Nature Portfolio | Nature Reviews Endocrinology
Francesco Prattichizzo, Angelica Giuliani, Emanuela Mensa’, Jacopo Sabbatinelli, Valeria De Nigris, Maria Rita Rippo, Lucia La Sala, Antonio Domenico Procopio, Fabiola Olivieri, Antonio Ceriello,
Metformin is the first-choice therapy to lower glycaemia and manage type 2 diabetes. Continuously emerging epidemiological data and experimental models are showing additional protective effects of metformin against a number of age-related diseases (ARDs), e.g., cardiovascular diseases and cancer. This evidence has prompted the design of a specific trial, i.e., the Targeting Aging with Metformin (TAME) trial, to test metformin as an anti-ageing molecule. However, a unifying or prevailing mechanism ...
Tópico(s): Diet and metabolism studies
2018 - Elsevier BV | Ageing Research Reviews
Francesco Prattichizzo, Valeria De Nigris, Stefano Micheloni, Lucia La Sala, Antonio Ceriello,
Recent clinical trials have demonstrated a strong cardiovascular (CV) protective effect of sodium/glucose cotransporter (SGLT) 2 inhibitors, a recently introduced class of hypoglycaemic agents. The improvement in glycated haemoglobin and other conventional risk factors explains only a portion of the observed reduction in CV risk. A relevant feature of SGLT2‐inhibitor‐treated diabetic patients is the increase in circulating levels of ketone bodies, which has been proposed to mediate part of the beneficial ...
Tópico(s): Diet and metabolism studies
2018 - Wiley | Diabetes Obesity and Metabolism
Claudio Sassanelli, Giuditta Pezzotta, Fabiana Pirola, Roberto Sala, Antonio Margarito, Mariangela Lazoi, Angelo Corallo, Mónica Rossi, Sergio Terzi,
Nowadays, product service systems (PSSs) and smart products are surging in the market and acquiring a strategic role for companies' survival. Manufacturers, compelled towards the transformation process into PSS providers, have to face the challenge of building up knowledge for successfully providing such complex solutions, also resorting to the help of more effective IT systems and tools. The need to adopt a collaborative design platform is starting to be raised also in the PSS context, since companies ...
Tópico(s): Digital Transformation in Industry
2018 - Inderscience Publishers | International Journal of Product Lifecycle Management
Matteo Gastaldi, Elisabetta Zardini, Rosaria Leante, Maddalena Ruggieri, Gianna Costa, Eleonora Cocco, Giovanna De Luca, Ivana Cataldo, Tiziana Biagioli, Clara Ballerini, Massimiliano Castellazzi, Enrico Fainardi, P Pettini, Mauro Zaffaroni, Debora Giunti, Elisabetta Capello, Gaetano Bernardi, Emilio Ciusani, Claudia Giannotta, Eduardo Nobile‐Orazio, Elena Bazzigaluppi, Gabriella Passerini, Roberta Bedin, Patrizia Sola, Rinaldo Brivio, Guido Cavaletti, Arianna Sala, Antonio Bertolotto, Gaetano Desina, Maurizio Leone, Sara Mariotto, Sérgio Ferrari, Andreina Paternoster, Davide Giavarina, Francesco Lolli, Diego Franciotta,
This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroinflammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2017 - Springer Science+Business Media | Neurological Sciences
Leticia Sala, Antonio Bascones Martínez, A. Carrillo de Albornoz,
Tópico(s): Orthodontics and Dentofacial Orthopedics
2016 - Springer Nature | Clinical Oral Investigations
Francesco Prattichizzo, Valeria De Nigris, Lucia La Sala, Antonio Domenico Procopio, Fabiola Olivieri, Antonio Ceriello,
Aging is a complex phenomenon driven by a variety of molecular alterations. A relevant feature of aging is chronic low‐grade inflammation, termed “inflammaging.” In type 2 diabetes mellitus (T2DM), many elements of aging appear earlier or are overrepresented, including consistent inflammaging. T2DM patients have an increased death rate, associated with an incremented inflammatory score. The source of this inflammation is debated. Recently, the senescence‐associated secretory phenotype (SASP) has been ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2016 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
Adriana Ariza, Cristobalina Mayorga, María Salas, Inmaculada Doña, Ángela Martín‐Serrano Ortiz, Ezequiel Pérez‐Inestrosa, Dolores Pérez‐Sala, Antonio Guzman, María I. Montañez, Marı́a José Torres,
Abstract The optimal recognition of penicillin determinants, including amoxicillin (AX), by specific IgE antibodies is widely believed to require covalent binding to a carrier molecule. The nature of the carrier and its contribution to the antigenic determinant is not well known. Here we aimed to evaluate the specific-IgE recognition of different AX-derived structures. We studied patients with immediate hypersensitivity reactions to AX, classified as selective or cross-reactors to penicillins. Competitive ...
Tópico(s): Food Allergy and Anaphylaxis Research
2016 - Nature Portfolio | Scientific Reports
Diabetes mellitus--whether driven by insulin deficiency or insulin resistance--causes major alterations in muscle metabolism. These alterations have an impact on nutrient handling, including the metabolism of glucose, lipids, and amino acids, and also on muscle mass and strength. However, the ways in which the distinct forms of diabetes affect muscle mass differ greatly. The most common forms of diabetes mellitus are type 1 and type 2. Thus, whereas type 1 diabetic subjects without insulin treatment ...
Tópico(s): Diet and metabolism studies
2015 - Springer Nature | Cellular and Molecular Life Sciences
Sabatino Cuomo, Maria Della Sala, Antonio Novità,
In coarse-grained, unsaturated soils, heavy rainstorms may cause either shallow landslides or superficial soil erosion. The triggering of both of these phenomena is related to infiltration, runoff and overland flow, which are key processes requiring investigation. In particular, the quantitative estimates of the sediment yield at the outlet of mountain basins requires suitable physically based modelling. In this paper, the available approaches to soil erosion analysis are first reviewed, and the ...
Tópico(s): Landslides and related hazards
2015 - Elsevier BV | Geomorphology