Rosemary Righter, Jon Ashworth, Nick Nuttall Environment Correspondent, Oliver Holt Chief Sports Correspondent, Robert Cole, Andrew Pierce, Sally Brock, James Moore, Simon Barnes, Robin Eggar, Richard Hobson, A. J. Cotton, Philip Howard, Roland Watson Chief political correspondent, Richard Anderson, Jeremy Kingston, Clive Davis, Brain Cane, Lynne Truss, Alan H. Sommerstein, Ian Machin, Valerie Elliott and James Landale, Heather Neill, Joe Joseph, Giles Coren, John O'Leary Education Editor, Carl Evans, Pat Gibson, Donald Hutera, Stewart Tendler Crime Correspondent, Keith Carter, Dominic Walsh, Steve Bird, Shirley English, Martin Porter, Anthony Burton, Tim Reid, Louis Blom-Cooper (Chairman), Dalya Alberge Arts Correspondent, Michael Mulvihill, Libby Purves, Daniel Barnett, Mark Inglefield, Rodney Milnes, Anthony G. Phillips, Gavin Ashenden, Linda Saunders, Peter Barnard, Anthea Lawson, Suzannah Oliver, Martin Fuller, Salman Rushdie, Russell Kempson, Geoffrey Cutte, David Lister, Philip Webster and Valerie Elliott, Frank Leboeuf, Matt Dickinson Football Correspondent, Susan Clark, Gary Slapper, Steuart & Francis, Simon de Bruxelles, John Hopkins Golf Correspondent, Geoffrey Dean, William Taylor, Adam Jones, Tony Morris, Marcus Binney, Stuart Nicholson, Raymond Keene, Adam Sage, David Robinson, Clive Mathieson, Arnold Wolfendale, President, Paul Wilkinson, Roy Roebuck, Christopher Walker Chief Ireland Correspondent, Chris Ayres Media Business Correspondent, Cathy Harris, Oliver Holt, Richard Owen, S. M. Wainde, John Goodbody, Michael Harvey and Martin Fletcher, Tony Narula, Philippa Morrall, Alexander McCall Smith, Douglas Gardner, David Hands Rugby Correspondent, Julian Muscat, John Allison, Nick Szczepanik, Dominic Kennedy, James Doran, Alex O'Connell, Paul McCann Media Correspondent, Kevin McCarra, Chris McGrath, Melissa Kite Political Reporter, Hilda Gaddum, Peter Riddell, Ben MacIntyre, John Malpas, Michael Gove, Richard Beeston Diplomatic Editor, Michael Dynes, Richard Miles, Lea Paterson, Michael Horsnell, Nigel Summerley, Dr Jane Collins Children's Teeth, Nigel Hawkes Science Editor, Carl Mortished International Business Editor, Laura Peek, Frances Gibb, Sam Kiley, Oliver Wright and Melissa Kite, Tom Baldwin Deputy Political Editor, Simon Crompton, Lea Paterson Economics Correspondent, Sally Patten, Patience Wheatcroft, David Lammy,
... Opening Brazil to the world World Music: Caetano Veloso's eclectic and urbane style is now appealing ...
2000 - Gale Group | TDA
... following articles citing this article:MARÍA JOSÉ ALONSO VELOSO António Carvalho de Parada, el teólogo portugués próximo a Olivares que instigó la versión censurada de Política de Dios de Quevedo, Bulletin of Hispanic Studies 98, no.88 (Sep 2021): 767–796.https://doi.org/10.3828/bhs.2021.45María José Alonso Veloso Una diatriba manuscrita inédita contra Política de Dios ...
Tópico(s): Spanish Linguistics and Language Studies
1958 - University of Chicago Press | Modern Philology
Jonathan Northcroft, Waldemar Januszczak, John Dugdale, Mark Ridley, Nicolas Balfour, Michael Barrymore, Matthew Wall, Sue Baker, Joanne Segars, Michael Wright, Nigel Botherway, Tony Booth, Barbara Hall, Aa Gill, David Barber, Darren Gough, Christopher Higgins, A Ross, Otis Ferry, Helen Davies, Nicholas Rufford, Rita Konig, Jason Dawe, John Peter, V S, Pam Barrett, Gideon Garter, Emma Moore, Amanda Ursell, Simon Wise, Jonathan Miller, Jim Munro football editor, Lesley White, Devika Bhat, Christopher Somerville, J D, Amanda Hall, Michael Hare Duke, Ivo Tennant, Nicolette Jones, Ferdinand Mount, David Gower, Kathryn Cooper, Colln Davy, Lucy Hughes-Hallett, David Smith, P D, Tim Richards, Alastair McCall, Peter Sharkey, Rory Godson, David Cracknell Political Editor, Nick Pitt, Ron Ciarke, Neil Wormald, E P, Andrew Sullivan, Clive Davis, Guy Dennis, Ellen MacArthur, Eddie Irvine, Tony Allen-Mills, Simon Wilde, Martin James, Tom Walker, Phil Smith, Anthony Sattin, Robert Winnett, Tom Otley, Irwin Stelzer, Faye Campbell (art historian), Peter Wilson, Rosie Millard, David Dougill, Rachel Dobson, Nicholas Hellen Social Affairs Editor, Jimmy Apostolou, Wilfred Owen, Jon Furmston, Marcus Tanner, David Hewson, Cally Law, Ian Hoyle, Emma Gibson Energy campainger, Jonathon Carr-Brown, Hugh Canning, Geraldine Hackett Education Correspondent, Jeremy Clarkson, Richard Wilson, Edward Porter, Peter Conradi, David Cairns, Louise Taylor, Peter Kemp, Alan Brownjohn, Victoria Segal, J Osborne-Hennessey, Gwen Harlow, Dominic Dromgoole, Travis Elborough, Liz Edwards, Sam Murphy, George Perry, Adam Nathan, Nick Crowe's, Shelley von Strunckel, Jeremy Guscott, Paul Durman City Editor, Jill Douglas, Richard Johnson, D Jackson, Stuart Wavell, Roger Eglin, Paul Donovan, Tom Conran, Monsieur Mangetout, Hugh McIlvanney, Chris Woodhead, Lucinda Kemeny, Bernard Crick, Derek Clements, Paul Driver, John Humphrys, Nicholas Hellen, Richard Brooks, Ian Hawkey, Alex Clark, Christopher Morgan, David Leppard, Amber Cowan, Paul Durman, Mark Ludlow, Hugh Jamieson, Alicia Wyllie, Dj dolly, Mark Edwards, Mick Dennis, Alex clark, Susan Clark, Lucy Wakefield, Chrissy lley, Fluid Canvas, Danny O'Brien, Rubert Steiner, Patrick Rattigan, Karen Gold, Alan Combes, Matt Peskett editor, Hermund Ardalen, Raymond Keene, Gareth Huw Davies, Fiona Morrow, M Shah, David Cracknell, Tim Richardson, Jayesh Ghaghda, Cosmo Landesman, Robbie Hudson, Nick Talbot, Diana Wright, Brigid McConville, Louise Faylor, Stephen Jones, Dominic O'Connell, Dr Raphael Papadopoulos, Barry Flatman, Uzi Mahnaimi, Nick Cain, Rodica Pricop, Commodore R Leaman Director Corporate, Richard Evans, Jonathan Northcraft, Louise Armitstead, Kenneth Clarke, Natalie Graham, Brian O'Brien, Melinda Stevens, Caroline Donald, Nick Rennison, M J, Julie Cohen, Tim Moorey, Keith Wheatley, John Gray, David Walsh, Caroline Gascoigne, John Stern, Trevor Lewis, Jack Grimston, Mike Myles-White, Bryan Appleyard, Lois Rogers Medical Correspondent, Claudia Navone, Stephen Armstrong, John Elliott, Colin McDowell's, Mark Macaskill, Stuart Lockwood, Bethan Cole, Sheherazade Goldsmith, David Price, Richard Woods, Sonia O'Sullivan, Shane Watson, Lesley Gillilan, Maurice Chittenden, Richard Brooks Arts Editor, Judith O'Reilly, Paul Walter, Mark Franchetti, Craig Lord, Richard Rae, Ray Hutton, Ria Higgins, Susan Elkin, Jonathan Leake, Michael Sheridan, Guy Barker, Pamela Piles, John Harlow, Simon Callow, Godfrey Smith, Ian Thomson, Barry Collins, Dipesh Gadher, Gillian Wilmot, James Edsberg, Waldemer Januszczak, Stuart Conway, A A Gill, Matthew Campbell, Brian Glanville, Louise Johncox, John Carey, Enda Leahy, Tom Robbins, David Sumner Smith, Nick Fielding, David Michels chief executive of Hilton, Nico Ladenis, Claudia Croft, Humayun Gauhar, Jason Mellor, Cherry Norton, Michael Vincent, Stephen Pettitt, Jason Corcoran, Sally Kinnes, Naomi Caine, Nigel Powell, Shaul Adar, Chris Grove, David Wickers, Simon Buckland, Minette Marrin, John Aizlewood, Peter Schmeichel, George Davis, Mark Hodson, Andrew Frankel, Dominic Midgley, Joe Lovejoy, Jonathan Futrell, Graham Norwood, Rupert Steiner, F. Courtney, David Budworth, Hugh Pearman, Dan Cairns, Paul Stephen Lubicz, Pete Oliver, Sir David Watson, Jay McInerney, Graham Allen Mp, Tony Allen-mills, Roger Radford, David Smith Economics Editor, Hugh Bradley, Sarah Baxter, Ian Staies, Helen Vandevelde, Matthew Goodman, India Knight, Steve Grant, Richard Whiteside, Kingston Smith, Sandy Gall, Danny Danziger, Barry Newcombe, Dominic Rushe, Richard Lewis, Boris Schapiro, Karen Robinson,
... Advertising Items Iglu Villas Multiple Classified Advertising Items Veloso Tours Multiple Display Advertising Items Laskarina Holidays Multiple ... Rattle, asks Hugh Canning New vamps for old Antonio Pappano's first night in charge was also ...
2002 - Gale Group | Sunday Times HA GDA
Ana Lúcia Luís, Sandra Amado, Stefano Geuna, Jorge Rodrigues, Maria José Simões, José D. Santos, Federica Fregnan, Stefania Raimondo, António Veloso, António Ferreira, Paulo Armada-da-Silva, Artur S.P. Varejão, Ana Colette Maurício,
We have recently described the sequence of functional and morphologic changes occurring after a standardized sciatic nerve crush injury. An 8-week post-injury time was used because this end point is the far most used. Unexpectedly, both functional and morphological data revealed that animals had still not recovered to normal pre-injury levels. Therefore, the present study was designed in order to prolong the observation up to 12 weeks. Functional recovery was evaluated using sciatic functional index ( ...
Tópico(s): Pain Management and Treatment
2007 - Elsevier BV | Journal of Neuroscience Methods
Ana Lúcia Luís, Jorge Rodrigues, Stefano Geuna, Sandra Amado, Yuki Shirosaki, Jennifer M. Lee, Federica Fregnan, M.A. Lopes, António Veloso, António Ferreira, José D. Santos, Paulo Armada-da-Silva, Artur S.P. Varejão, Ana Colette Maurício,
Poly(lactic-co-glycolic acid) (PLGA) nerve tube guides, made of a novel proportion (90:10) of the two polymers, poly(L-lactide): poly(glycolide) and covered with a neural cell line differentiated in vitro, were tested in vivo for promoting nerve regeneration across a 10-mm gap of the rat sciatic nerve. Before in vivo testing, the PLGA 90:10 tubes were tested in vitro for water uptake and mass loss and compared with collagen sheets. The water uptake of the PLGA tubes was lower, and the mass loss was ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2008 - Mary Ann Liebert, Inc. | Tissue Engineering Part A
Rui Silva, Bruna Silva, Cristiana Fernandes, Pedro Morouço, Nuno Alves, António Veloso,
When a limb suffers a fracture, rupture, or dislocation, it is traditionally immobilized with plaster. This may induce discomfort in the patient, as well as excessive itching and sweating, which creates the growth of bacteria, leading to an unhygienic environment and difficulty in keeping the injury clean during treatment. Furthermore, if the plaster remains for a long period, it may cause lesions in the joints and ligaments. To overcome all of these disadvantages, orthoses have emerged as important ...
Tópico(s): Advanced X-ray and CT Imaging
2024 - Multidisciplinary Digital Publishing Institute | Sensors
Isabel M.P.L.V.O. Ferreira, C. Veiros, Olı́via Pinho, Ana C. A. Veloso, António M. Peres, António Mendonça,
Terrincho cheese is an uncooked, pressed cheese made from raw whole ovine milk from the “Churra da Terra Quente” breed. It requires a minimum ripening time of 30 d. A detailed evaluation of the effect of ripening time on the breakdown of the casein fractions, along with the formation of major breakdown products of casein hydrolysis, was monitored by HPLC to contribute to a more complete characterization of this product. In 30-d-old cheeses, only 20% of αS1-casein remained intact; the β-casein fraction ...
Tópico(s): Food Allergy and Anaphylaxis Research
2006 - Elsevier BV | Journal of Dairy Science
Produção Nacional
C. A. C. Veloso, ANTÔNIO HENRIQUE LOPES OEIRAS, E. J. M. Carvalho, Francisco Ronaldo Sarmanho de Souza,
O presente trabalho foi desenvolvido no período compreendido entre abril de 1997 e novembro de 1998, com o objetivo de avaliar o efeito da aplicação do nitrogênio e do potássio em diferentes níveis de calagem sobre a produtividade e qualidade do fruto do abacaxizeiro, num Latossolo Amarelo distrófico (Oxisol), no município de Capitão Poço, localizado na mesorregião do nordeste paraense. Os tratamentos constaram de quatro doses de nitrogênio (0; 6; 12 e 18 g/planta de N) na forma de uréia; quatro doses ...
Tópico(s): Banana Cultivation and Research
2001 - Sociedade Brasileira de Fruticultura | Revista Brasileira de Fruticultura
Bruno Oliveira, Helena R. Torres, Pedro Morais, Fernando Veloso, António L. Baptista, Jaime C. Fonseca, João L. Vilaça,
Abstract Chronic Venous Disorders (CVD) of the lower limbs are one of the most prevalent medical conditions, affecting 35% of adults in Europe and North America. Due to the exponential growth of the aging population and the worsening of CVD with age, it is expected that the healthcare costs and the resources needed for the treatment of CVD will increase in the coming years. The early diagnosis of CVD is fundamental in treatment planning, while the monitoring of its treatment is fundamental to assess ...
Tópico(s): Entomological Studies and Ecology
2023 - Nature Portfolio | Scientific Reports
Produção Nacional
Laura Marcelly Teixeira Gomes, Alice Duarte Santos Veloso, Antônio Cavalcanti Oliveira Filho, Ítalo Filipe França, Maria Fernanda Souza Ramos, Maria José Lages de Oliveira, Verônica Oliveira Dias,
Em meio à pandemia da doença Coronavírus (COVID-19), a prática odontopediátrica passa por novo cenário, considerando que crianças podem ser portadoras assintomáticas do vírus e o ambiente odontológico considerado um local de risco. Procedimentos odontológicos envolvem exposição à saliva e secreções nasofaríngea, produção de aerossóis e gotículas, fontes de transmissão. Além dos cuidados de biossegurança comuns nos consultórios e dos recomendados pela Organização Mundial da Saúde contra o Coronavírus, ...
Tópico(s): Scientific and Engineering Research Topics
2021 - | Unimontes Científica
Daniel Martín‐Vertedor, Nuno Rodrigues, Ítala M.G. Marx, Ana C. A. Veloso, António M. Peres, José Alberto Pereira,
The effect of thermal sterilization processes on the physicochemical parameters and sensory characteristics of Californian-style black olives, from 'Hojiblanca' and 'Manzanilla Cacereña' brine solutions, were evaluated. Two-way ANOVA showed that 'Hojiblanca' olives had a lower phenols content and defect intensity and that increasing the sterilization period resulted in a decrease in total phenols and an increase of the cooked defect. The impact of thermal sterilization was further evaluated using a ...
Tópico(s): Potato Plant Research
2020 - Elsevier BV | Food Control
Shidiq Nur Hidayat, Kuwat Triyana, Inggrit Fauzan, Trisna Julian, Danang Lelono, Yusril Yusuf, Nor Hasrul Akhmal Ngadiman, Ana C. A. Veloso, António M. Peres,
An electronic nose (E-nose), comprising eight metal oxide semiconductor (MOS) gas sensors, was used in situ for real-time classification of black tea according to its quality level. Principal component analysis (PCA) coupled with signal preprocessing techniques (i.e., time set value preprocessing, F1; area under curve preprocessing, F2; and maximum value preprocessing, F3), allowed grouping the samples from seven brands according to the quality level. The E-nose performance was further checked using ...
Tópico(s): Analytical Chemistry and Chromatography
2019 - Multidisciplinary Digital Publishing Institute | Chemosensors
Alejandra Fernández, Angélica M. Cárdenas, Jessica Astorga, Pablo Veloso, Antonio Alvarado, Paulina M. Merino, Danilo Siqueira Pino, Daniel Reyes-Court, Marcela Hernández,
Tópico(s): Immune Response and Inflammation
2019 - Springer Nature | Clinical Oral Investigations
Produção Nacional
Revisado por pares
Tamara Daiane de Souza, Alisson Carraro Borges, Amanda Fernandes Braga, Renato Welmer Veloso, Antônio Teixeira de Matos,
Phytoremediation is a technique in which plants are used to treat contaminated media. The objective of this study was to monitor the influence of the parameters pH, phosphate concentration, and nitrate concentration in the process of arsenic absorption by Lemna valdiviana Phil. The response surface methodology was used to analyze the data to subsidize actions that maximize the phytoremediation process. A central composite rotational design (CCRD) was used with 3 variables including 6 axial points ...
Tópico(s): Clay minerals and soil interactions
2019 - Elsevier BV | Chemosphere
Imam Tazi, Kuwat Triyana, Dwi Siswanta, Ana C. A. Veloso, António M. Peres, Luís G. Dias,
This study shows the potential application of a potentiometric electronic tongue coupled with a lab-made DataLogger device for the classification of dairy products according to the type of milk used in their production, i.e., natural, fermented and UHT milk. The electronic tongue device merged a commercial pH electrode and 15 lipid/polymeric membranes, which were obtained by a drop-by-drop technique. The potentiometric signal profiles gathered from the 16 sensors, during the analysis of the 11 dairy ...
Tópico(s): Analytical Chemistry and Sensors
2018 - Springer Science+Business Media | Journal of Food Measurement & Characterization
Produção Nacional
Revisado por pares
Leonardo Roever, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha‐Silva, Fernando César Veloso, Antonio Casella–Filho, Paulo Magno Martins Dourado, Antônio Carlos Palandri Chagas,
Ectopic visceral fat (VF) and subcutaneous fat (SCF) are associated with cardiovascular risk factors. Gender differences in the correlations of cardiovascular disease risk factors and ectopic fat in the Brazilian population still lacking. Cross-sectional study with 101 volunteers (50.49% men; mean age 56.5 ± 18, range 19–74 years) drawn from the Uberlândia Heart Study underwent ultrasonography assessment of abdominal visceral adipose tissue with convex transducer of 3.5 MHz of frequency. The thickness ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2016 - Wolters Kluwer | Medicine
Produção Nacional
Revisado por pares
Leonardo Roever, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha‐Silva, Fernando César Veloso, Antonio Casella–Filho, Paulo Magno Martins Dourado, Antônio Carlos Palandri Chagas,
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. Ectopic fat is a risk factor for multiple CVD risk factors, including hypertension, dyslipidemia, diabetes, and the metabolic syndrome (MetS) [ 1 Thom T. Haase N. Rosamond W. Howard V.J. Rumsfeld J. Manolio T. et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics — 2006 update: a report from the American Heart Association Statistics Committee ...
Tópico(s): Cardiovascular Function and Risk Factors
2015 - Elsevier BV | International Journal of Cardiology
Luís G. Dias, Zelda Alberto, Ana C. A. Veloso, António M. Peres,
Tópico(s): Biosensors and Analytical Detection
2015 - Springer Science+Business Media | Journal of Food Measurement & Characterization
Produção Nacional
Revisado por pares
Helma Jane Ferreira Veloso, Antônio Augusto Moura da Silva, Heloísa Bettiol, Marcelo Zubarán Goldani, Fernando Lamy Filho, Vanda Maria Ferreira Simões, Rosângela Fernandes Lucena Batista, Marco Antônio Barbieri,
Abstract Background To analyze trends in LBW (low birth weight) rate using birth registry data and identify factors associated with LBW in São Luís comparing two birth cohorts separated by a 12-year interval. Methods 2,426 births were included in 1997/98 and 5,040 in 2010. The dependent variable was LBW (<2,500 g). Multiple logistic regression was performed to determine the association of independent variables with LBW. Data were also obtained from SINASC (Brazilian National Birth Registry) to analyze ...
Tópico(s): Breastfeeding Practices and Influences
2014 - BioMed Central | BMC Pregnancy and Childbirth
Produção Nacional
Viviane G. C. Abreu, Geone Maia Corrêa, Thiago M. Silva, Humberto S Fontoura, Denise Carmona Cara, Dorila Piló‐Veloso, Antônio FC Alcântara,
Lycnophora pinaster is used by the traditional Brazilian medicine for the treatment of inflammations. Anti-inflammatory activity of Lycnophora pinaster was investigated for extracts, fractions, and isolated compounds of their aerial parts. The hexane extract (HE) provided α-amyrin, lupeol, mixture of α-amyrin and lupeol, mixture of 3-O-acetyl-lupeol and 3-O-acetyl-pseudotaraxasterol, and mixture of the steroids stigmasterol and sitosterol. The aqueous extract (WE) provided a fraction containing alkaloids ( ...
Tópico(s): Insect Pest Control Strategies
2013 - BioMed Central | BMC Complementary and Alternative Medicine
Produção Nacional
Revisado por pares
Fábio Pereira, Roberto G. S. Berlinck, Edson Rodrigues‐Filho, Katyuscya Veloso, Antônio G. Ferreira, Vinícius Padula,
THE BRAZILIAN COASTLINE.The chemical investigation of the MeOH extract from the bryozoan B. dentata MeOH yielded tambjamines A (1), C (3), D (4), K (6), aldehyde 8 and the new tambjamine J1(9), while the extract of its predator, the nudibranch Tambja stegosauriformis, yielded tambjamines C and K, along with aldehyde 8. Furodisinin lactone (11) was isolated from the nudibranch Hypselodoris lajensis, a compound previously isolated from Dysidea sponges.The alkaloid 2,5,6-tribromo-N-methylgramine (12) was ...
Tópico(s): Marine Sponges and Natural Products
2012 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Alison Geraldo Pacheco, Thiago M. Silva, Rozângela Magalhães Manfrini, William S. T. Sallum, Lucienir Pains Duarte, Dorila Piló‐Veloso, Antônio Flávio de Carvalho Alcântara, Vagner Fernandes Knupp,
STEM OF Aristolochia esperanzae Kuntze (ARISTOLOCHIACEAE).From the ethanolic extract of the stem of A. esperanzae ethyl and methyl fatty acid esters, fatty acids, aristolochic I and II acids, and β-cubebin were isolated.In addiction asarinin, populifolic and 2-oxo-populifolic acids, aristolactams AIa and AII, and sitosterol 3-O-β-D-glucopyranoside were also isolated and firstly described in the species.Asarinin and β-cubebin showed antibacterial activity against Bacillus cereus and aristolochic acid ...
Tópico(s): Heavy Metals in Plants
2010 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Helma Jane Ferreira Veloso, Antônio Augusto Moura da Silva,
To determine the prevalence of excess body weight and abdominal obesity and assess the association with socioeconomic, demographic and behavioral factors among adults of Maranhão, Brazil.Multistage cluster sample investigated through a household survey on 1,005 adults aged 20 to 59 years (393 men and 612 women). Anthropometric measures: weight, height and waist circumference (WC) were assessed. Abdominal obesity was defined as WC > 80 for women and WC > 94 for men. Body mass index (BMI), weight in kilograms ...
Tópico(s): Body Composition Measurement Techniques
2010 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Eli F. Pimenta, Aline Maria de Vita-Marques, Aristeu Gomes Tininis, Mirna Helena Regali Seleghim, Lara Durães Sette, Katyuscya Veloso, Antônio G. Ferreira, David E. Williams, Brian O. Patrick, Doralyn S. Dalisay, Raymond J. Andersen, Roberto G. S. Berlinck,
A fractional factorial design approach has been used to enhance secondary metabolite production by two Penicillium strains. The method was initially used to improve the production of bioactive extracts as a whole and subsequently to optimize the production of particular bioactive metabolites. Enhancements of over 500% in secondary metabolite production were observed for both P. oxalicum and P. citrinum. Two new alkaloids, citrinalins A (5) and B (6), were isolated and identified from P. citrinum cultures ...
Tópico(s): Fungal Biology and Applications
2010 - American Chemical Society | Journal of Natural Products
Produção Nacional
Revisado por pares
M. H. Kossuga, Simone Possedente de Lira, Shayna McHugh, Yohandra Reyes Torres, Bruna de Araújo Lima, Reginaldo Bruno Gonçalves, Katyuscya Veloso, Antônio G. Ferreira, Rosana Moreira da Rocha, Roberto G. S. Berlinck,
The chemical investigation of the crude extract of an ascidian of the genus Didemnumled to the isolation of the modified diketopiperazine rodriguesines A (1) and (2) as a mixture of homologues, which could be identified by analysis of spectroscopic data including MS/MS experiments. The investigation of a second Didemnumsp. led to the isolation of N-acetyl-rodriguesine A (3) and N-acetyl-rodriguesine B (4). The absolute configuration of compounds 1and 2could be established by hydrolysis and Marfey's ...
Tópico(s): Synthesis and Catalytic Reactions
2009 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society
Produção Nacional
Revisado por pares
Alison Geraldo Pacheco, Patrícia Machado de Oliveira, Dorila Piló‐Veloso, Antônio Flávio de Carvalho Alcântara,
The genus Aristolochia,an important source of physiologically active compounds that belong to different chemical classes, is the subject of research in numerous pharmacological and chemical studies. This genus contains a large number of terpenoid compounds, particularly diterpenes. This work presents a compilation of the 13C-NMR data of 57 diterpenoids described between 1981 and 2007 which were isolated from Aristolochia species. The compounds are arranged skeletonwise in each section, according ...
Tópico(s): Traditional Chinese Medicine Analysis
2009 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
M. H. Kossuga, Andréa Mendes do Nascimento, Juliana Quero Reimão, André G. Tempone, Noemi Nosomi Taniwaki, Katyuscya Veloso, Antônio G. Ferreira, Bruno C. Cavalcanti, Cláudia Pessoa, Manoel Odorico de Moraes, Alejandro M. S. Mayer, Eduardo Hajdu, Roberto G. S. Berlinck,
Investigation of the bioactive crude extract from the sponge Plakortis angulospiculatus from Brazil led to the isolation of plakortenone (1) as a new polyketide, along with five known polyketides (2–6) previously isolated from other Plakortis sponges. The known polyketides were tested in antileishmanial, antitrypanosomal, antineuroinflammatory, and cytotoxicity assays. The results show that plakortide P (3) is a potent antiparasitic compound, against both Leishmania chagasi and Trypanosona cruzi, and ...
Tópico(s): Marine Sponges and Natural Products
2008 - American Chemical Society | Journal of Natural Products
Produção Nacional
Revisado por pares
Helma Jane Ferreira Veloso, Antônio Augusto Moura da Silva, Marco Antônio Barbieri, Marcelo Zubarán Goldani, Fernando Lamy Filho, Vanda Maria Ferreira Simões, Rosângela Fernandes Lucena Batista, Maria Teresa Seabra Soares de Britto e Alves, Heloísa Bettiol,
Epidemias de malária ocorrem anualmente nos municípios da Região Amazônica, Brasil, no entanto os serviços de saúde não adotam, de maneira sistemática, instrumentos para detecção e contenção oportunas desses eventos. O objetivo foi caracterizar as epidemias de malária na região segundo duração, espécie de Plasmodium e vulnerabilidade das populações. Foi avaliado um sistema de monitoramento automatizado da incidência da malária, com base no diagrama de controle segundo quartis, para identificar as ...
Tópico(s): Global Maternal and Child Health
2013 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Felipe P.G. Euzébio, Flávio José Leite dos Santos, Dorila Piló‐Veloso, Antônio F. C. Alcântara, Ana Lúcia Tasca Góis Ruiz, João Ernesto de Carvalho, Mary Ann Foglio, Dalton L. Ferreira‐Alves, Ângelo de Fátima,
Natural products are great prototypes for the design of new anticancer agents. The plant-derived natural product 6α,7β-dihydroxyvouacapan-17β-oic acid (1) is promising for the development of more potent antiproliferative agents against human cancer cells. Indeed, its lactone derivative 6α-hydroxyvouacapan-7β,17β-lactone (2), a non-natural furanoditerpene, exhibited higher anticancer activity than compound 1. Herein, we describe the synthesis and antiproliferative activity of six new Mannich derivatives ...
Tópico(s): Plant biochemistry and biosynthesis
2010 - Elsevier BV | Bioorganic & Medicinal Chemistry
Produção Nacional
Revisado por pares
Priscila Marques de Macedo, Dayvison Francis Saraiva Freitas, Andréa G. Varon, Cristiane da Cruz Lamas, Livia Cristina Fonseca Ferreira, Andrea D’Ávila Freitas, Marcel Treptow Ferreira, Estêvão Portela Nunes, Marilda Mendonça Siqueira, Valdiléa G. Veloso, Antônio Carlos Francesconi do Valle,
Institute of Infectious Diseases, Fiocruz, on 10 March 2020 complaining of an 8-month history of progressive weight loss; multiple cervical, axillary, and inguinal lymph node enlargements; abdominal distension; and disseminated cutaneous lesions (Fig 1).A histopathological examination of the left inguinal lymph node revealed chronic granulomatous lymphadenitis with the presence of multiple budding fungal structures typical of Fig 1. Ulcerated skin lesions covered by crusts on the patient's face and ...
Tópico(s): Antifungal resistance and susceptibility
2020 - Public Library of Science | PLoS neglected tropical diseases