Produção Nacional
Revisado por pares
Giovanni Borsoi, António Santos Silva, P. Menezes, António Candeias, José Mirão,
The analytical characterization of mortar samples from the roman archaeological site of Pisões, located in Southern Portugal, were carried out by means of X-ray diffractometry (XRD), thermogravimetry (TGA-DTA), optical and electron scanning microscopy (SEM-EDS), potentiometry and combustion analysis. The Pisões archaeological complex includes a villa rustica, characterized by well-preserved mosaics and thermal baths, as well as a mill and a mausoleum. Countryside villae epitomized the Romanization ...
Tópico(s): Conservation Techniques and Studies
2019 - Elsevier BV | Construction and Building Materials
Produção Nacional
Revisado por pares
Milene Borsoï, Camila B. Antonio, Liz Girardi Müller, Alice Fialho Viana, Vivian Hertzfeldt, Paula Lunardi, Caroline Zanotto, Patrícia Nardin, Ana Paula Ravazzolo, Stela Maris Kuze Rates, Carlos‐Alberto Gonçalves,
Glutamate perturbations and altered neurotrophin levels have been strongly associated with the neurobiology of neuropsychiatric disorders. Environmental stress is a risk factor for mood disorders, disrupting glutamatergic activity in astrocytes in addition to cognitive behaviours. Despite the negative impact of stress-induced neuropsychiatric disorders on public health, the molecular mechanisms underlying the response of the brain to stress has yet to be fully elucidated. Exposure to repeated swimming ...
Tópico(s): Stress Responses and Cortisol
2014 - Elsevier BV | Pharmacology Biochemistry and Behavior
Produção Nacional
Revisado por pares
Milene Borsoï, Camila B. Antonio, Alice Fialho Viana, Patrícia Nardin, Carlos‐Alberto Gonçalves, Stela Maris Kuze Rates,
The forced swim test (FST) is widely used to evaluate the antidepressant-like activity of compounds and is sensitive to stimuli that cause depression-like behaviors in rodents. The immobility behavior observed during the test has been considered to represent behavioral despair. In addition, some studies suggest that the FST impairs rats' performance on cognitive tests, but these findings have rarely been explored. Thus, we investigated the effects of the FST on behavioral tests related to neuropsychiatric ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2014 - Elsevier BV | Physiology & Behavior
Produção Nacional
Revisado por pares
Gilda Neves, Milene Borsoï, Camila B. Antonio, Mariana A. Pranke, Andresa Heemann Betti, Stela Maris Kuze Rates,
Immobility time in the forced swimming has been described as analogous to emotional blunting or apathy and has been used for characterizing schizophrenia animal models. Several clinical studies support the use of NMDA receptor antagonists to model schizophrenia in rodents. Some works describe the effects of ketamine on immobility behavior but there is variability in the experimental design used leading to controversial results. In this study, we evaluated the effects of repeated administration of ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2017 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Daniel Giura da Silva, Jean F. R. Ribeiro, Daniela De Vita, Lorenzo Cianni, Caio Haddad Franco, Lúcio H. Freitas-Júnior, Carolina Borsoi Moraes, Josmar R. Rocha, Antonio C. B. Burtoloso, Peter W. Kenny, Andrei Leitão, Carlos A. Montanari,
The effects on potency of cruzain inhibition of replacing a nitrile group with alternative warheads were explored. The oxime was almost an order of magnitude more potent than the corresponding nitrile and has the potential to provide access to the prime side of the catalytic site. Dipeptide aldehydes and azadipeptide nitriles were found to be two orders of magnitude more potent cruzain inhibitors than the corresponding dipeptide nitriles although potency differences were modulated by substitution ...
Tópico(s): Click Chemistry and Applications
2017 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Giovanni Borsoi, Martha Tavares, Rosário Veiga, António Santos Silva,
The conservation and durability of historical renders must be carried out through compatible techniques and materials. An important operation is the restitution of historical renders cohesion, turned friable by the loss of binder, usually due to physical and/or chemical actions. Surface consolidation is based on the use of materials with aggregating properties. This operation is reached usually through the application of organic or mineral consolidants, but inorganic consolidants are becoming preferred ...
Tópico(s): Conservation Techniques and Studies
2012 - Oxford University Press | Microscopy and Microanalysis
Patrícia M. Pascoal, Giovanni Borsoi, Rosário Veiga, Paulina Faria, António Santos Silva,
Historical renders are exposed to several degradation processes that can lead to a wide range of anomalies, such as scaling, detachments, and pulverization. Among the common anomalies, the loss of cohesion and of adhesion are usually identified as the most difficult to repair; these anomalies still need to be deeply studied to design compatible, durable, and sustainable conservation treatments. The restitution of render cohesion can be achieved using consolidating products. Nevertheless, repair ...
Tópico(s): Cultural Heritage Materials Analysis
2014 - Taylor & Francis | Studies in Conservation
Produção Nacional
Revisado por pares
Anderlise Borsoi, W.M. Quinteiro-Filho, Atílio Sersun Calefi, Antônio José Piantino Ferreira, Claudete S. Astolfi‐Ferreira, Jorge Camilo Flório, João Palermo‐Neto,
We analysed the effects of cold stress (19 ± 1°C, 6 h /day, from the first to the seventh day of life) applied to specific pathogen free (SPF) chickens. On experimental Day 1 (ED1), chicks were divided into four groups: C (not infected and kept under thermoneutral condition); CS (not infected and cold stressed); PC (Salmonella Heidelberg (SH) infected and kept under thermoneutral condition) and PCS (SH infected and cold stressed). High concentrations of corticosterone were found in the cold stressed birds ...
Tópico(s): Stress Responses and Cortisol
2015 - Taylor & Francis | Avian Pathology
Produção Nacional
Revisado por pares
Gilmar Antônio Santa Catarina, Cleide Borsoi, Daiane Romanzini, Diego Piazza, Sandra Raquel Kunst, Lisete Cristine Scienza, Ademir J. Zattera,
ABSTRACT Powder coatings have been receiving attention because they are environmentally friendly. They do not contain solvents in their composition, and their components have decorative and corrosion‐protection functions, among many others. However, the presence of polymers in their composition increases the risk of combustion in adverse situations. In this context, this study aims to develop and characterize acrylic‐based powder paints with the addition of 2 wt % and 4 wt % montmorillonite clays (MMT) ...
Tópico(s): Fire dynamics and safety research
2017 - Wiley | Journal of Applied Polymer Science
Giovanni Borsoi, Martha Tavares, Rosário Veiga, António Santos Silva,
This work is inserted in a wider project aiming at the conservation and durability of historical renders, through compatibles techniques and materials; in particular the restitution of cohesion of historical renders, turned friable by the loss of binder due to physical or chemical actions, is studied. Surface consolidation, directed to restore cohesion and stability, is based on the use of materials with aggregating properties. This operation is reached usually through the application of organic ...
Tópico(s): Conservation Techniques and Studies
2012 - Trans Tech Publications | Materials science forum
Giovanni Borsoi, B.A. Lubelli, Rob van Hees, Rosário Veiga, António Santos Silva,
Novel nanomaterials, such as nanosilica or nano-titanium oxide, have been developed in the last decade for the conservation of the built heritage. Among nanomaterials, nanolimes have acquired a considerable relevance due to their potentialities as consolidant product. The so-called nanolimes, colloidal dispersions of calcium hydroxide nanoparticles in alcohols, have been successfully applied as pre-consolidants on frescos and paper, and their use has later been extended to plasters, renders and ...
Tópico(s): Conservation Techniques and Studies
2015 - Elsevier BV | Journal of Cultural Heritage
Giovanni Borsoi, B.A. Lubelli, Rob van Hees, Rosário Veiga, António Santos Silva,
The potentialities of nanomaterials for application in the field of conservation have been widely investigated in the last two decades. Among nanomaterials, nanolimes, i.e., dispersions of lime nanoparticles in alcohols are promising consolidating products for calcareous materials. Nanolimes are effective in recovering the very superficial loss of cohesion of decayed materials, but they do not always provide sufficient mass consolidation. This limitation is mainly related to the deposition of the ...
Tópico(s): Cultural Heritage Materials Analysis
2016 - Springer Science+Business Media | Applied Physics A
Giovanni Borsoi, B.A. Lubelli, Rob van Hees, Rosário Veiga, António Santos Silva, Laura Colla, Laura Fedele, Patrizia Tomasin,
Consolidation treatment is a common practice in the field of conservation. However, when considering calcareous materials, there is a lack of efficient and durable consolidants. Colloidal dispersions of Ca(OH)2 nanoparticles, commonly known as nanolimes, can effectively recover the superficial loss of cohesion. However, they do not always guarantee in-depth mass consolidation. The aim of this paper is to give directions for improving in-depth deposition of nanolime dispersions when applied on limestone. ...
Tópico(s): Calcium Carbonate Crystallization and Inhibition
2016 - Elsevier BV | Colloids and Surfaces A Physicochemical and Engineering Aspects
Giovanni Borsoi, B.A. Lubelli, Rob van Hees, Rosário Veiga, António Santos Silva,
Abstract Calcareous materials such as limestone and lime-based mortars, widely used in the Built Heritage, are often subjected to degradation processes that can lead to loss of cohesion and material loss. Consolidation of these materials with liquid products via the surface is a common practice; however, the most used consolidation products (e. g. TEOS-based) show a poor physical-chemical compatibility with calcareous substrates. For application on calcareous materials, the so-called nanolimes, i. ...
Tópico(s): Cultural Heritage Materials Analysis
2017 - De Gruyter | Restoration of Buildings and Monuments
Giovanni Borsoi, B.A. Lubelli, Rob van Hees, Rosário Veiga, António Santos Silva,
Surface consolidation is a common practice in the conservation of the built heritage. However, the effectiveness of consolidation of calcareous materials is often doubtful, due to the lack of effective and compatible consolidation products. Dispersions of calcium hydroxide nanoparticles in alcohol, the so-called nanolimes, can recover the superficial consolidation of calcareous substrates. Nevertheless, they are often not able to guarantee an in-depth consolidation. Previous research by the authors ...
Tópico(s): Microbial Applications in Construction Materials
2017 - Elsevier BV | Construction and Building Materials
Carlo Federici, Francesca Perego, Ludovica Borsoi, Valentina Crosta, Andrea Zanichelli, Antonio Gidaro, Rosanna Tarricone, Marco Cicardi,
Objectives To explore treatment behaviours in a cohort of Italian patients with hereditary angioedema due to complement C1-inhibitor deficiency (C1-INH-HAE), and to estimate how effects and costs of treating attacks in routine practice differed across available on-demand treatments. Design Cost analyses and survival analyses using attack-level data collected prospectively for 1 year. Setting National reference centre for C1-INH-HAE. Participants 167 patients with proved diagnosis of C1-INH-HAE, who ...
Tópico(s): Complement system in diseases
2018 - BMJ | BMJ Open
Produção Nacional
Revisado por pares
Atílio Sersun Calefi, W.M. Quinteiro-Filho, Adriana de Siqueira, Ana Paula Nascimento de Lima, Daniel Sanzio Gimenes da Cruz, Nicolle Queiroz Hazarbassanov, Fernanda Auciello Salvagni, Anderlise Borsoi, Cristina de Oliveira Massoco, Paulo César Maiorka, Antônio José Piantino Ferreira, João Palermo‐Neto,
Information on the dynamics of the chicken immune system during bacterial or parasite challenge in the presence or absence of stressful situations may provide a better understanding of the complex mechanisms behind these diseases. Necrotic enteritis (NE) had been controlled previously by the proper use of antimicrobial agents; however, more recently, NE has reemerged in many countries. The imposed restrictions on antimicrobial use and/or the intensive productive programs implemented by producers ...
Tópico(s): Bird parasitology and diseases
2019 - Elsevier BV | Veterinary Immunology and Immunopathology
Produção Nacional
Revisado por pares
Pasquale Linciano, Cecilia Pozzi, Lucia Dello Iacono, F. Di Pisa, Giacomo Landi, Alessio Bonucci, Sheraz Gul, Maria Kuzikov, Bernhard Ellinger, Gesa Witt, Nuno Santarém, Catarina Baptista, Caio Haddad Franco, Carolina Borsoi Moraes, Wolfgang G. Müller, Ulrike Wittig, Rosaria Luciani, Antony Sesenna, Antonio Quotadamo, Stefania Ferrari, Ina Pöhner, Anabela Cordeiro‐da‐Silva, Stefano Mangani, Luca Costantino, Maria Paola Costi,
2-Amino-benzo[d]thiazole was identified as a new scaffold for the development of improved pteridine reductase-1 (PTR1) inhibitors and anti-trypanosomatidic agents. Molecular docking and crystallography guided the design and synthesis of 42 new benzothiazoles. The compounds were assessed for Trypanosoma brucei and Leishmania major PTR1 inhibition and in vitro activity against T. brucei and amastigote Leishmania infantum. We identified several 2-amino-benzo[d]thiazoles with improved enzymatic activity ( ...
Tópico(s): Trypanosoma species research and implications
2019 - American Chemical Society | Journal of Medicinal Chemistry
Produção Nacional
Revisado por pares
Juliana C. Gomes, Lorenzo Cianni, Jean F. R. Ribeiro, Fernanda dos Reis Rocho, Samelyn da Costa Martins Silva, Pedro Henrique Jataí Batista, Carolina Borsoi Moraes, Caio Haddad Franco, Lúcio H. Freitas-Júnior, Peter W. Kenny, Andrei Leitão, Antonio C. B. Burtoloso, Daniela De Vita, Carlos A. Montanari,
The structure-activity relationship for nitrile-based cruzain inhibitors incorporating a P2 amide replacement based on trifluoroethylamine was explored by deconstruction of a published series of inhibitors. It was demonstrated that the P3 biphenyl substituent present in the published inhibitor structures could be truncated to phenyl with only a small loss of affinity. The effects of inverting the configuration of the P2 amide replacement and linking a benzyl substituent at P1 were observed to be ...
Tópico(s): HIV/AIDS drug development and treatment
2019 - Elsevier BV | Bioorganic & Medicinal Chemistry
Produção Nacional
Revisado por pares
Viviane Flumignan Zétola, Marcos Christiano Lange, Valéria Cristina Scavasine, Rodrigo Bazán, Gabriel Pereira Braga, Ana Claúdia Celestino Bezerra Leite, Soraia Ramos Cabette Fábio, Octávio Marques Pontes‐Neto, Carla Heloísa Cabral Moro, Gisele Sampaio, Edson Bor-Seng Shu, Marcelo de Lima Oliveira, Maramélia Miranda, Daniela Laranja Gomes, Pedro Antônio Pereira de Jesus, Jamary Oliveira‐Filho, Wagner Mauad Avelar, Gabriel R. de Freitas, Rafael Borsoi, Corina Puppo, Silvia Cocorullo, Alejandro M. Brunser, Ayrton Roberto Massaro, Natan M. Bornstein, Alexander Y. Razumovsky, Massimo Del Sette,
The role of patent foramen ovale is a field of debate and current publications have increasing controversies about the patients' management in young undetermined stroke. Work up with echocardiography and transcranial Doppler (TCD) can aid the decision with better anatomical and functional characterization of right-to-left shunt (RLS). Medical and interventional strategy may benefit from this information.a group of experts from the Latin American participants of the Neurosonology Research Group (NSRG) ...
Tópico(s): Cardiovascular Health and Disease Prevention
2019 - Karger Publishers | Cerebrovascular Diseases
Marcos Roberto Pinheiro, André Mateus Barreiros, Grace Bungenstab Alves, Marcelo Reis Nakashima, Beatriz Ferraz Scigliano, Andrio Filipe Amaral Soares, Antonio Artur dos Santos, Hellen Renata Guimarães Borsoi, Antônio Carlos de Azevedo, Fabiano do Nascimento Pupim, Caio Breda, Fernando Nadal Junqueira Villela,
Tópico(s): Paleontology and Stratigraphy of Fossils
2024 - Elsevier BV | CATENA
Produção Nacional
Revisado por pares
Araceli Borsoi Ferrari, Carlos Alberto Diehl, Marcos Antônio de Souza,
Management accounting has played an important role in strategic control, even in organizations like cooperatives. The aim of this paper is to investigate the use of management-accounting information as a support for strategic control in cooperatives. To do that it a literature review was conducted, followed by the application of a structured questionnaire with open and closed questions addressed to cooperatives of the mountain area of Rio Grande do Sul state and the metropolitan region of Porto ...
Tópico(s): Social and Economic Solidarity
2011 - UNIVERSIDADE DE SÃO PAULO | Revista de Contabilidade e Organizações
Produção Nacional
Revisado por pares
Pasquale Linciano, Carolina Borsoi Moraes, Laura Maria Alcântara, Caio Haddad Franco, Bruno S. Pascoalino, Lúcio H. Freitas-Júnior, Sara Macedo, Nuno Santarém, Anabela Cordeiro‐da‐Silva, Sheraz Gul, Gesa Witt, Maria Kuzikov, Bernhard Ellinger, Stefania Ferrari, Rosaria Luciani, Antonio Quotadamo, Luca Costantino, Maria Paola Costi,
Basing on a library of thiadiazole derivatives showing anti-trypanosomatidic activity, we have considered the thiadiazoles opened forms and reaction intermediates, thiosemicarbazones, as compounds of interest for phenotypic screening against Trypanosoma brucei (Tb), intracellular amastigote form of Leishmania infantum (Li) and Trypanosoma cruzi (Tc). Similar compounds have already shown interesting activity against the same organisms. The compounds were particularly effective against T. brucei and ...
Tópico(s): Synthesis and Biological Evaluation
2018 - Elsevier BV | European Journal of Medicinal Chemistry
Marcus Vinícius Sandoval Paixão, Antônio Carlos Borsoi Neto, Luiz Antônio Mota, Leticia Lima Sinfrônio, Anna Marcella da Silva Guimarães, Antônio Resende Fernandes,
O mamão é uma fruteira que possui uma grande aceitação pela população em geral, e sua produção vem crescendo a cada ano. O principal fator de produção é a semente e a germinação o primeiro fator a se considerar para a produção da muda. Objetivou-se avaliar o efeito da giberelina na emergência de plântulas de mamoeiro cultivar aliança. O experimento foi realizado em um delineamento em blocos casualizados, com cinco tratamentos e quatro repetições, com cinquenta sementes por repetição. Para cada avaliação ...
Tópico(s): Soil Management and Crop Yield
2023 - | Revista Contemporânea
Produção Nacional
Revisado por pares
Vitória Evangelista Dos Santos, Antônio Carlos Borsoi Neto, Luiz Antônio Mota, Ednaldo Miranda de Oliveira, Marcus Vinícius Sandoval Paixão,
O estudo do substrato adequado é de grande importância na produção da muda para implantação de um pomar produtivo, pois fornece condições ideais para a germinação e desenvolvimento. Objetivou-se avaliar o efeito de diferentes substratos minerais na emergência e desenvolvimento inicial de plântulas de mamoeiro cultivar aliança. O experimento foi realizado em delineamento em blocos casualizados, com cinco tratamentos e quatro repetições. Foram utilizadas cinquenta sementes por repetição, e para cada ...
Tópico(s): Leaf Properties and Growth Measurement
2023 - Faculdade Novo Milênio | Revista Foco
Carla Rognoni, Diego Cuccurullo, Ludovica Borsoi, Luigi Bonavina, Emanuele Asti, Feliciano Crovella, Uberto Andrea Bassi, Gabriele Carbone, Francesca Guerini, Paolo De Paolis, Silvia Pessione, Vincenzo Maria Greco, Elisabetta Baccarini, Giorgio Soliani, Carlo Sagnelli, Clotilde Crovella, Vincenzo Trapani, Carlo De Nisco, Emilio Eugeni, Federico Zanzi, Enrico De Nicola, Antonio Marioni, Alessandro Rosignoli, Roberto Silvestro, Rosanna Tarricone, Micaela Piccoli,
Abstract With the development of newer meshes and approaches to hernia repair, it is currently difficult to evaluate their performances while considering the patients’ perspective. The aim of the study was to assess the clinical outcomes and quality of life consequences of abdominal hernia repairs performed in Italy using Phasix and Phasix ST meshes through the analysis of real-world data to support the choice of new generation biosynthetic meshes. An observational, prospective, multicentre study ...
Tópico(s): Hip and Femur Fractures
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Geedre Adriano Borsoi, Bruna Verediana Müller, Doádi Antônio Brena,
O objetivo deste estudo foi testar equações matemáticas e estimar o volume de galhos para espécies de três grupos de valor econômico em uma área de Floresta Ombrófila Mista, situada na região nordeste do estado do Rio Grande do Sul. Foi realizada a cubagem rigorosa dos galhos de 287 árvores-amostra. Além dos galhos de cada árvore selecionada, o restante do fuste comercial (resíduo) foi considerado na determinação do volume total de galhos. As árvores-amostra selecionadas foram separadas e classificadas ...
Tópico(s): Agricultural and Food Sciences
2012 - Editora Unicentro | Revista Ambiência
Produção Nacional
Geedre Adriano Borsoi, Bruna Verediana Müller, Doádi Antônio Brena,
O objetivo deste estudo foi determinar o percentual de casca para os grupos de espécies de baixo, médio e alto valor econômico em uma área de Floresta Ombrófila Mista, situada na região nordeste do estado do Rio Grande do Sul. Foi realizada a cubagem rigorosa de 302 árvores-amostra para a obtenção do diâmetro, espessura de casca, altura comercial e volume comercial. As árvores-amostra foram separadas e classificadas em grupos de valor econômico. Na determinação do percentual de casca, foi utilizado ...
Tópico(s): Forest Biomass Utilization and Management
2013 - Editora Unicentro | Revista Ambiência
Gustavo Miranda Cremonini, Alejandro Pio de Souza, Kevilim de Jesus Leite, Antônio Carlos Borsoi Neto, Marcus Vinícius Sandoval Paixão, Antônio Resende Fernandes,
A Physalis angulata L. se desenvolve como planta silvestre nas zonas tropicais da América, sendo o seu centro de origem indeterminado. Objetivou-se avaliar diferentes doses de giberelina na germinação de sementes Physalis. A pesquisa foi realizada no laboratório de Sementes e propagação de plantas do Instituto Federal do Espírito Santo (IFES) – Campus Santa Teresa. Foram utilizadas 500 sementes de Physalis, distribuídas em delineamento inteiramente casualizado com 5 tratamentos e 4 repetições, sendo ...
Tópico(s): Soil Management and Crop Yield
2022 - Brazilian Journal of Development | Brazilian Journal of Development
Angélica Couto Correa, Rafaela Barreto Cazaroto Grobério, Antônio Carlos Borsoi Neto, Carlos Avelino de Sousa Pancieri, Antônio Resende Fernandes, Marcus Vinícius Sandoval Paixão,
A pesquisa foi realizada com o objetivo de avaliar diferentes doses de giberelina na emergência de plântulas de urucum e realizado no viveiro de mudas do Instituto Federal do Espírito Santo – Campus Santa Teresa, submetendo as sementes aos seguintes tratamentos: imersão por 30 minutos em: água (testemunha); solução de giberelina a 1.000 mg.L-1, 2.000 mg.L-1, 3.000 mg.L-1 e 4.000 mg.L-1. O delineamento experimental foi inteiramente casualizado (DIC), com 5 tratamentos e quatro repetições, com cada unidade ...
Tópico(s): Environmental and biological studies
2022 - Brazilian Journal of Development | Brazilian Journal of Development