
Luiz Fernando dos Santos, Joana Costa Martins, Karmel de Oliveira Lima, Lígia Ferreira Gomes, Maryanne Trafani de Melo, Antônio Cláudio Tedesco, Luís D. Carlos, Rute A. S. Ferreira, Rogéria Rocha Gonçalves,
Luminescent spherical, redispersable, and monodisperse Er3+,Yb3+ co-doped Y2O3 nanoparticles were synthesized by homogenous precipitation followed by thermal annealing. Cubic Y2O3 nanoparticles exhibited high colloidal stability in water and biological medium and 90% cell viability toward glioblastoma multiforme cell lines. Confocal microscopy revealed cellular internalization of Y2O3 nanoparticles. Upon excitation at 980 nm, efficient near-infrared to visible upconversion luminescence from Y2O3: ...
Tópico(s): Luminescence and Fluorescent Materials
2021 - Elsevier BV | Physica B Condensed Matter

Sued Eustáquio Mendes Miranda, Janaína de Alcântara Lemos, Renata Salgado Fernandes, Juliana de Oliveira Silva, Flaviano Melo Ottoni, Danyelle M. Townsend, Domenico Rubello, Ricardo José Alves, Geovanni Dantas Cassali, Lucas Antônio Miranda Ferreira, André Luís Branco de Barros,
Lapachol (LAP) is a natural compound with various biological properties, including anticancer activity. However, its clinical application is limited due to the low aqueous solubility and potential adverse side effects. Nanoemulsions are drug delivery systems that can assist in the administration of hydrophobic drugs, increasing their bioavailability and protecting from degradation. Thus, this study aimed to prepare a LAP-loaded nanoemulsion (NE-LAP), and evaluate its antitumor activity. For this purpose, ...
Tópico(s): Morinda citrifolia extract uses
2020 - Elsevier BV | Biomedicine & Pharmacotherapy

Jorge Antônio Gonzaga Santos, Luís Alfredo Pinheiro Leal Nunes, Wanderley José de Melo, Ademir Sérgio Ferreira de Araújo,
Composting is recognized as one of the most cost-effective and environmentally sound alternatives for organic waste recycling. Long-composted wastes have the potential to substitute for inorganic fertilizers. We investigated the effect of tannery sludge compost (TSC) amendment rates on microbial biomass and activity in Brazilian soils. The soils (sandy and clayey soils) were amended with TSC at rates of 0 (control), 7.5, 15, 30 and 60 Mg ha−1 (equivalent to 0, 0.3, 0.6, 1.2 and 2.4 g per 100 g of soil, ...
Tópico(s): Phosphorus and nutrient management
2011 - Elsevier BV | European Journal of Soil Biology

Adrielle Martins Monteiro Alves, Lílian Melo de Miranda Fortaleza, Antônio Luíz Martins Maia Filho, Danniel Cabral Leão Ferreira, Charllyton Luís Sena da Costa, Vicente Galber Freitas Viana, José Zilton Lima Verde Santos, Rauirys Alencar de Oliveira, G.O.M. Gusmão, Luı́s Eduardo Silva Soares,
Tópico(s): Medical and Biological Ozone Research
2018 - Springer Science+Business Media | Lasers in Medical Science

André Ferreira do Nascimento, Renata de Azevedo Melo Luvizotto, André Soares Leopoldo, Ana Paula Lima‐Leopoldo, Fábio Rodrigues Ferreira Seiva, Luís Antônio Justulin, Maeli Dal‐Pai‐Silva, Katashi Okoshi, Xiangdong Wang, Antônio Carlos Cicogna,
Leptin resistance has been associated with cardiac lipotoxicity; however, whether leptin resistance is a risk factor associated with cardiac lipotoxicity at different time points in diet-induced obesity is unclear. The objective of this study was to evaluate this relationship. Male Wistar rats were fed a normal chow diet (12% from fat) or a high-fat diet (49% from fat) for 15 and 45 weeks, respectively. The adiposity index, body weight and co-morbidities were evaluated. Heart lipotoxicity was assessed ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2011 - Elsevier BV | Life Sciences
Manuel Rocha Melo, Manuel Ferreira‐Magalhães, Filipa Flôr-de-Lima, Mariana Rodrigues, Mílton Severo, Luís Almeida-Santos, Alberto Caldas Afonso, Pedro Pita Barros, António Ferreira,
Dedicated pediatricians in emergency departments (EDs) may be beneficial, though no previous studies have assessed the related costs and benefits/harms. We aimed to evaluate the net benefits and costs of dedicated emergency pediatricians in a pediatric ED.Cost-consequences analysis of visits to a pediatric ED of a tertiary hospital. Two pediatric ED Medical Teams (MT) were compared: MT-A (May-September 2012), with general pediatrics physicians only; and MT-B (May-September 2013), with emergency dedicated ...
Tópico(s): Pneumonia and Respiratory Infections
2016 - Public Library of Science | PLoS ONE
Ludhmila Abrahão Hajjar, Jean‐Louis Vincent, Filomena Regina Barbosa Gomes Galas, Andrew Rhodes, Giovanni Landoni, E Osawa, Renato Melo, M Sundin, Solimar Miranda Grande, Fábio Antônio Gaiotto, Pablo Maria Alberto Pomerantzeff, Luís Alberto Oliveira Dallan, Rafael Alves Franco, Rosana Ely Nakamura, Luiz Augusto Ferreira Lisboa, Juliano Pinheiro de Almeida, A Gerent, Dayenne Hianae Souza, Maria Alice Gaiane, Júlia Tizue Fukushima, Clarice Lee Park, Cristiane Maciel Zambolim, Graziela Santos Rocha Ferreira, Tânia Mara Varejão Strabelli, Felipe Lourenço Fernandes, Lígia Câmara, S Zeferino, Valter Garcia Santos, M Piccioni, Fábio Biscegli Jatene, José Otávio Costa Auler Júnior, Roberto Kalil Filho,
Vasoplegic syndrome is a common complication after cardiac surgery and impacts negatively on patient outcomes. The objective of this study was to evaluate whether vasopressin is superior to norepinephrine in reducing postoperative complications in patients with vasoplegic syndrome.This prospective, randomized, double-blind trial was conducted at the Heart Institute, University of Sao Paulo, Sao Paulo, Brazil, between January 2012 and March 2014. Patients with vasoplegic shock (defined as mean arterial ...
Tópico(s): Cardiac Arrest and Resuscitation
2016 - Lippincott Williams & Wilkins | Anesthesiology

Raizza Barros Sousa Silva, Roseane de Araújo Portela, Luís Fernando Batista Arruda, Jefferson da Silva Ferreira, Érick Platiní Ferreira de Souto, Ana Lucélia de Araújo, Maria de Fátima Madeira, Antônio Flávio Medeiros Dantas, Márcia Almeida de Melo,
Abstract The main clinical, anatomopathological, and molecular aspects of the infection by Leishmania infantum are described in two cats with multicentric cutaneous, nodular, and ulcerated lesions. The animals were submitted to a clinical examination, followed by serological, molecular and parasitological exams, with culture and isolation of the parasite, and subsequent isoenzymatic characterization. The animals were euthanized and necropsied. Case 1 was an adult, female, mixed-bred stray cat. Case ...
Tópico(s): Trypanosoma species research and implications
2020 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology

Maria Luíza Bazzo, Lisléia Golfetto, Pâmela Cristina Gaspar, Ana Flávia Pires, Mauro Cunha Ramos, Matías Franchini, William Antunes Ferreira, Magnus Unemo, Adele Schwartz Benzaken, Lucas Ferrari de Andrade, Guilherme H.O. Arnhold, Maria Luíza Bazzo, Adele Schwartz Benzaken, Simone Veloso Faria de Carvalho, Ligia Maria Bedeschi Costa, Maria Rita Rabelo Costa, Risoleyde Matos, Luís Gustavo Dias, Letícia Maria Eidt, William Antunes Ferreira, Matías Franchini, Pâmela Cristina Gaspar, Antonio Gerbase, Lisléia Golfetto, J S Gomes, Leonor Henriette de Lannoy, Hanalydia Melo Machado, Jorge Martins, Cartaxo Muniz, L F M Pereira, Ana Flávia Pires, Caio César de Pinho Porto, Mauro Cunha Ramos, Federico Di Rocco, Thais Mattos dos Santos, Marcos André Schörner, Marta Filipa Silva, Moacir P. Silva, Roberto José Carvalho Silva, Loeci Natalina Timm, Walmir Sousa Vasconcelos, Cássia Maria Zoccoli,
Gonorrhoea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are major public health concerns globally. Enhanced AMR surveillance for gonococci is essential worldwide; however, recent quality-assured gonococcal AMR surveillance in Latin America, including Brazil, has been limited. Our aims were to (i) establish the first nationwide gonococcal AMR surveillance, quality assured according to WHO standards, in Brazil, and (ii) describe the antimicrobial susceptibility of clinical gonococcal isolates ...
Tópico(s): Reproductive Health and Contraception
2018 - Oxford University Press | Journal of Antimicrobial Chemotherapy

Iúna Carmo Ribeiro Gonçalves, Ademir Sérgio Ferreira de Araújo, Luís Alfredo Pinheiro Leal Nunes, Antônio Aécio de Carvalho Bezerra, Wanderley José de Melo,
The study aimed to evaluate the phytoavailability of heavy metals (Cr, Cd, Ni and Pb) concentrations in leaves and grains, and yield of cowpea (Vigna unguiculata L) grown in soil amended with composted tannery sludge (CTS) for two consecutive years.The experiments were carried out in 2009 and 2010 in soil amended with CTS at 0, 5, 10, 20, and 40 Mg ha -1 .The CTS amendment rates applied were above 10 Mg ha -1 , increased Cr concentrations in cowpea leaves.There were not increases in the heavy metals concentrations ...
Tópico(s): Geotechnical and construction materials studies
2014 - Editora da Universidade Estadual de Maringá (Eduem) | Acta Scientiarum Agronomy

Vanessa Moreira, Luís Cláudio Lima de Jesus, Rossy-Eric Pereira Soares, Luis Douglas Miranda Silva, Bruno Pinto, Maria Norma Melo, Antonio Marcus de Andrade Paes, Silma Regina Ferreira Pereira,
Leishmaniasis is a neglected tropical disease caused by >20 species of the protozoan parasite Leishmania Meglumine antimoniate (Glucantime) is the first-choice drug recommended by the World Health Organization for the treatment of all types of leishmaniasis. However, the mechanisms of action and toxicity of pentavalent antimonials, including genotoxic effects, remain unclear. Therefore, the mechanism by which meglumine antimoniate causes DNA damage was investigated for BALB/c mice infected by Leishmania ( ...
Tópico(s): Glutathione Transferases and Polymorphisms
2017 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy

Ives Charlie‐Silva, Natália Martins Feitosa, Juliana Moreira Mendonça-Gomes, Daniela Chemim de Melo Hoyos, Cristiano Campos Mattioli, Silas Fernandes Eto, Dayanne Carla Fernandes, Marco Antônio de Andrade Belo, Juliana de Oliveira Silva, André Luís Branco de Barros, José Dias Corrêa, Gustavo Batista Menezes, Hirla Costa Silva Fukushima, Tássia Flávia Dias Castro, Ricardo Carneiro Borra, Felipe Pierezan, Nathalie Ferreira Silva de Melo, Leonardo Fernandes Fraceto,
Mucoadhesive polymeric nanocapsules have attracted interest of researchers from different fields from natural sciences because of their ability to interact with the mucosa and increase drug permeation. Anesthesia by immersion causes absorption through the skin and gills of fish, so it is important to evaluate the exposure of these organs to drug nanosystems. Benzocaine (BENZ) is one of the most popular anesthetic agents used in fish anesthesia, but it has drawbacks because of its low bioavailability, ...
Tópico(s): Advanced Drug Delivery Systems
2020 - Public Library of Science | PLoS ONE

Joseany Andrade Santos, Luís Alfredo Pinheiro Leal Nunes, Wanderley José de Melo, Marcia Barreto do Vale Figueiredo, Rajeev Pratap Singh, Antônio Aécio de Carvalho Bezerra, Ademir Sérgio Ferreira de Araújo,
Tannery wastes generation is increasing every year and a suitable method for tannery sludge management is necessary in order to decrease this environmental problem. The composting is recognized as a suitable method for sludge recycling.. The effect of tannery sludge compost (TSC) rates on growth, nodulation and N fixation of cowpea was investigated. Sandy and clayey soils were amended with TSC at rates of 0, 7.5, 15, 30, and 60 t ha-1. The shoot dry weight of cowpea plants 45 days after emergence ( ...
Tópico(s): Plant Growth Enhancement Techniques
2011 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo

José Henrique Ledo, Estefania P. Azevedo, Danielle Beckman, Felipe C. Ribeiro, Luís E. Santos, Daniela S. Razolli, Grasielle C. Kincheski, Helen M. Melo, Maria Bellio, Antônio Lúcio Teixeira, Lı́cio A. Velloso, Débora Foguel, Fernanda G. De Felice, Sérgio T. Ferreira,
Considerable clinical and epidemiological evidence links Alzheimer's disease (AD) and depression. However, the molecular mechanisms underlying this connection are largely unknown. We reported recently that soluble Aβ oligomers (AβOs), toxins that accumulate in AD brains and are thought to instigate synapse damage and memory loss, induce depressive-like behavior in mice. Here, we report that the mechanism underlying this action involves AβO-induced microglial activation, aberrant TNF-α signaling, and ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2016 - Society for Neuroscience | Journal of Neuroscience

Francis Tocafundo, Giselle de Souza Rodrigues, Elisângela dos Santos, Cláusio Antônio Ferreira de Melo, Dilze Maria Argôlo Magalhães, José Luís Pires, A. F. dos Santos, Edna Dora Martins Newman Luz,
Tópico(s): Plant Pathogenic Bacteria Studies
2021 - Springer Science+Business Media | Tropical Plant Pathology

Brunno Lemes de Melo, Stella Sousa Vieira, Ednei L. Antônio, Luís Felipe Neves dos Santos, Leslie Andrews Portes, Regiane Santos Feliciano, Helenita Antônia de Oliveira, José Antônio Silva, Paulo de Tarso Camillo de Carvalho, Paulo José Ferreira Tucci, Andrey Jorge Serra,
Introduction: Pulmonary arterial stenosis (PAS) is a congenital defect that causes outflow tract obstruction of the right ventricle (RV). Currently, negative issues are reported in the PAS management: not all patients may be eligible to surgeries; there is often the need for another surgery during passage to adulthood; patients with mild stenosis may have later cardiac adverse repercussions. Thus, the search for approaches to counteract the long-term PAS effects showed to be a current target. At the ...
Tópico(s): Pulmonary Hypertension Research and Treatments
2016 - Frontiers Media | Frontiers in Physiology

Eduardo Souza Leal, Luís Carlos Vinhas Ítavo, Cacilda Borges do Valle, Camila Celeste Brandão Ferreira Ítavo, Alexandre Menezes Dias, Gelson dos Santos Difante, Marcos Barbosa Ferreira, Lucimara Modesto Nonato, Gleice Kelli Ayardes de Melo, Antônio Leandro Chaves Gurgel,
Five cultivars of Urochloa brizantha (Hochst. ex A.Rich.) R.D. Webster (syn. of Brachiaria brizantha) were evaluated for nutritional value and an anti-nutritional factor (protodioscin), in order to determine whether protodioscin content was correlated with reduced feed quality. We evaluated cvv. Arapoty, Paiaguas, Xaraes, Marandu and Piata and grouped the results into summer, autumn, winter and spring seasons. Protodioscin content and chemical composition of leaves, in vitro digestibility and cumulative ...
Tópico(s): Soil Management and Crop Yield
2020 - CSIRO Publishing | Crop and Pasture Science

Luiz Cláudio de Melo Medina, Luís Carlos Vinhas Ítavo, Camila Celeste Brandão Ferreira Ítavo, Alexandre Menezes Dias, Antônio Leandro Chaves Gurgel, Lucimara Modesto Nonato, Angelo Herbet Moreira Arcanjo, Camila da Silva Zornitta, Paulo Eduardo de Oliveira Monteiro, Amarildo Pedro da Silva,
Tópico(s): Meat and Animal Product Quality
2023 - Springer Science+Business Media | Tropical Animal Health and Production

Omar Asdrúbal Vilca Mejía, Michel Pompeu Sá, Maurílio Onofre Deininger, Luís Roberto Palma Dallan, Rodrigo Coelho Segalote, Marco Antônio Praça Oliveira, Fernando Antibas Atik, Magaly Arrais dos Santos, Pedro Gabriel Melo de Barros e Silva, Rodrigo Milani, Alexandre Ciappina Hueb, Rosângela Monteiro, Ricardo Carvalho Lima, Luiz Augusto Ferreira Lisboa, Luís Alberto Oliveira Dallan, John D. Puskas, Fábio Biscegli Jatene,
Introduction: Advances in modern medicine have led to people living longer and healthier lives.Frailty is an emerging concept in medicine yet to be explored as a risk factor in cardiac surgery.When it comes to CABG surgery, randomized controlled clinical trials have primarily focused on low-risk (ROOBY, CORONARY), elevated-risk (GOPCABE) or high-risk patients (BBS), but not on frail patients.Therefore, we believe that off-pump CABG could be an important technique in patients with limited functional ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2017 - Brazilian Society of Cardiovascular Surgery | Brazilian Journal of Cardiovascular Surgery

Samara Cristina Ferreira-Machado, Nazareth N. Rocha, André Luiz Mencalha, Luiz Dione Barbosa de Melo, Camila Salata, Andréia Fortes Ribeiro, Thiago da Silva Torres, Carlos Alberto Mandarim‐de‐Lacerda, Paulo César Canary, Antônio Augusto de Freitas Peregrino, Luís Alexandre Gonçalves Magalhães, Januário B. Cabral‐Neto, Carlos Eduardo de Almeida,
Purpose: To investigate changes in cardiac functional parameters and the cardiac expression of angiotensin-converting enzyme (ACE), angiotensin II type 1 receptor (AT1), procollagen type I (proc-I) and transforming growth factor-β1 (TGF-β1) in rats irradiated at heart.
Tópico(s): Cardiovascular Function and Risk Factors
2010 - Taylor & Francis | International Journal of Radiation Biology

Maria Elisabeth de Araújo, Felipe Monteiro Gomes de Mattos, Felipe P. L. Melo, Laís de Carvalho Teixeira Chaves, Caroline Vieira Feitosa, Daniel Lino Lippi, Fabiana Cézar Félix‐Hackradt, Carlos Werner Hackradt, Jorge Luíz Silva Nunes, Zelinda M.A.N. Leão, Ruy Kenji Papa de Kikuchi, Antônio Vicente Ferreira, Pedro Henrique Cipresso Pereira, Cláudio Henrique Rodrigues de Macedo, Cláudio Luís Santos Sampaio, João Lucas Leão Feitosa,
Causal mechanisms for broad-scale reef fish diversity patterns are poorly understood and current knowledge is limited to trends of species richness. This work compared the effects of ecological drivers on components of fish diversity across reefs spanning over 2.000 km of the tropical Brazilian coastline. A quarter of communities' diversity is accountable to common and dominant species, while remaining species are rare. Low-latitude sites were more diverse in rare species. Communities along the ...
Tópico(s): Fish biology, ecology, and behavior
2020 - Elsevier BV | Marine Environmental Research

Marta Giovanetti, Francesco Pinotti, Camila Zanluca, Vagner Fonseca, Taishi Nakase, Andrea Cristine Koishi, Marcel Kruchelski Tschá, Guilherme Marques Soares, Gisiane Gruber Dorl, Antônio Ernesto Meister Luz Marques, Renato Silva de Sousa, Talita Adelino, Joilson Xavier, Carla de Oliveira, Sandro Patroca, Natália Rocha Guimarães, Hegger Fritsch, Maria Angélica Mares-Guia, Flávia Mauad Levy, Pedro Henrique de Oliveira Passos, Vinicius Leme da Silva, Luiz Augusto Pereira, Ana Flávia Mendonça, Isabel Luana de Macêdo, Davi Emanuel Ribeiro de Sousa, Gabriela Rodrigues de Toledo Costa, Márcio Botelho de Castro, Miguel de Souza Andrade, Filipe Vieira Santos de Abreu, Fabrício Souza Campos, Felipe Campos de Melo Iani, Maira Alves Pereira, Karina Ribeiro Leite Jardim Cavalcante, André Ricardo Ribas Freitas, Carlos F. Campelo de Albuquerque, Eduardo Marques Macário, Marlei Pickler Debiasi dos Anjos, Rosane Campanher Ramos, Aline Alves Scarpellini Campos, Adriano Pintér, Márcia Chame, Lívia Abdalla, Irina Nastassja Riediger, Sérvio Pontes Ribeiro, Ana I. Bento, Túlio de Oliveira, Carla Freitas, Noely Fabiana Oliveira de Moura, Allison Fabri, Cintia Damasceno dos Santos Rodrigues, Carolina Cardoso dos Santos, Marco Antônio Barreto de Almeida, Edmilson dos Santos, Jáder da Cruz Cardoso, Douglas A. Augusto, Eduardo Krempser, Luís Filipe Mucci, R. Gatti, Sabrina Fernandes Cardoso, João Augusto Brancher Fuck, Maria Goretti David Lopes, Ivana Lúcia Belmonte, Gabriela Mayoral Pedroso da Silva, Maiane Regina Ferreira Soares, Marilia de Melo Santos de Castilhos, Joseana Cardoso de Souza e Silva, Alceu Bisetto, Emanuelle Gemin Pouzato, Laurina Setsuko Tanabe, Daniele Akemi Arita, Ricardo Matsuo, Josiane dos Santos Raymundo, Paula Cristina Linder Silva, Ana Santana Araújo Ferreira Silva, Sandra Samila, Glauco Carvalho, Rodrigo G. Stábeli, Wildo Navegantes, Luciano Andrade Moreira, Álvaro Ferreira, Guilherme Garcia Pinheiro, Bruno Tardelli Diniz Nunes, Daniele Barbosa de Almeida Medeiros, Ana Cecília Ribeiro Cruz, Rivaldo Venâncio da Cunha, Wesley C. Van Voorhis, Ana María Bispo de Filippis, María Almirón, Edward C. Holmes, Daniel Ramos, Alessandro Romano, José Lourenço, Luíz Carlos Júnior Alcântara, Claudia Nunes Duarte dos Santos,
Despite the considerable morbidity and mortality of yellow fever virus (YFV) infections in Brazil, our understanding of disease outbreaks is hampered by limited viral genomic data. Here, through a combination of phylogenetic and epidemiological models, we reconstructed the recent transmission history of YFV within different epidemic seasons in Brazil. A suitability index based on the highly domesticated Aedes aegypti was able to capture the seasonality of reported human infections. Spatial modeling ...
Tópico(s): Primate Behavior and Ecology
2023 - American Association for the Advancement of Science | Science Advances
Pedro Baltazar, Antônio Ferreira de Melo, Nuno Moreira Fonseca, M. Lança, Ana Faria, Catarina O. Sequeira, Luísa Teixeira-Santos, Emília C. Monteiro, Luís Campos Pinheiro, Joaquim Calado, Cátia Sousa, Judit Morelló, Sofia A. Pereira,
Oxalate is a metabolic end-product whose systemic concentrations are highly variable among individuals. Genetic (primary hyperoxaluria) and non-genetic (e.g., diet, microbiota, renal and metabolic disease) reasons underlie elevated plasma concentrations and tissue accumulation of oxalate, which is toxic to the body. A classic example is the triad of primary hyperoxaluria, nephrolithiasis, and kidney injury. Lessons learned from this example suggest further investigation of other putative factors associated ...
Tópico(s): Connexins and lens biology
2023 - Multidisciplinary Digital Publishing Institute | Genes

Maxim Goncharov, Omar Asdrúbal Vilca Mejía, Camila Perez de Souza Arthur, Bianca Maria Maglia Orlandi, Alexandre Gonçalves de Sousa, Marco Antônio Praça Oliveira, Fernando Antibas Atik, Rodrigo Coelho Segalote, Marcos Gradim Tiveron, Pedro Gabriel Melo de Barros e Silva, Marcelo Arruda Nakazone, Luiz Augusto Ferreira Lisboa, Luís Alberto Oliveira Dallan, Zhe Zheng, Shengshou Hu, Fábio Biscegli Jatene,
The performance of traditional scores is significantly limited to predict mortality in high-risk cardiac surgery. The aim of this study was to compare the performance of STS, ESII and HiriSCORE models in predicting mortality in high-risk patients undergoing CABG.
Tópico(s): Cardiac Valve Diseases and Treatments
2021 - Public Library of Science | PLoS ONE

Diana Nara da Silva Oliveira, Carla Gardênia da Silva Melo, Luís Távora Furtado Ribeiro, João Paulo Guerreiro de Almeida, Edvar Ferreira Basílio, Carlos Rochester Ferreira de Lima, Edna Ribeiro de Castro, José Antônio Gabriel Neto,
O presente estudo almeja desvelar as concepções dos docentes sobre o uso das tecnológicos da informação e comunicação no contexto educacional, especificamente na Educação Básica do município de Jaguaruana-Ceará, bem como suas reflexões acerca dos desdobramentos da inserção desses recursos no período da pandemia do COVID-19, a partir do ensino remoto. Fundamentando-se em procedimentos metodológicos que misturam métodos quali-quantitativos, tendo como referência a pesquisa bibliográfica, a partir ...
Tópico(s): Healthcare during COVID-19 Pandemic
2020 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development

Felipe Tiago José dos Santos, Williams Nascimento de Siqueira, M. L. O. Santos, Henrique Antonio Silva, José Luís Ferreira Sá, T.S. Fernandes, N. H. Silva, Elvis Joacir de França, Edvane Borges da Silva, Ana Maria Mendonça de Albuquerque Melo,
Some phytochemicals have shown the potential of being radiomodifiers, especially phenolic compounds, such as lichenic secondary metabolites. To evaluate the phytochemical usnic acid as a radiomodifier, embryonic cells of molluscs have been used due to their ease of collection, high sensitivity to physical and chemical agents, well-known embryology and low cost for analysis.This study aimed to assess the radiosensitizing action of usnic acid on Biomphalaria glabrata embryos. Samples were irradiated ...
Tópico(s): Radioactive contamination and transfer
2018 - Taylor & Francis | International Journal of Radiation Biology

Stella Sousa Vieira, Ednei Luíz Antonio, Brunno Lemes de Melo, Luís Felipe Neves dos Santos, Eduardo Tadeu Santana, Regiane dos Santos Feliciano, Fábio Luiz Navarro Marques, Daniele de Paula Faria, Carlos Alberto Buchpiguel, José Antônio Silva, Paulo José Ferreira Tucci, Andrey Jorge Serra,
Tópico(s): Tissue Engineering and Regenerative Medicine
2020 - Springer Nature | Stem Cell Reviews and Reports

Luís Gustavo Cavalcante Reinaldo, Raimundo J. C. Araújo-Júnior, Thiago Melo Diniz, Rafael de Deus Moura, Antônio J. Meneses-Filho, Caio Victor Verçosa Macedo Furtado, Washington L. C. dos‐Santos, Dorcas Lamounier Costa, Kelsen Dantas Eulálio, Gabriel Reis Ferreira, Carlos Henrique Nery Costa,
Some patients with visceral leishmaniasis (VL), or kala-azar, suffer relapses and low quality of life despite adequate drug therapy, especially those co-infected with HIV. Occasionally, physicians indicate splenectomy, but the benefit of the procedure needs to be analyzed systematically. Therefore, a retrospective open cohort study was conducted in Teresina, Brazil. Inpatients from a reference hospital with relapsing VL who had a rescue splenectomy between 2012 and 2019 after the nationally recommended ...
Tópico(s): Ectopic Pregnancy Diagnosis and Management
2022 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene

Matheus Santos Melo, Luís Antônio Alvarado Cabrera, Shirley Verônica Melo Almeida Lima, Allan Dantas dos Santos, Lilian M. G. Bahia‐Oliveira, Renata Carla de Oliveira, Janaína de Sousa Menezes, Josivânia Arrais de Figueiredo, Viviane Fragoso de Moura Lane, Francisco Edilson Ferreira de Lima Júnior, Rosalynd Vinicios da Rocha Moreira,
Abstract Objective To analyse the spatial, temporal and spatial–temporal patterns of infant mortality associated with congenital toxoplasmosis in Brazil between the years 2000 and 2020. Methods Ecological study of time series, with spatial analysis and spatiotemporal scan of infant mortality associated with congenital toxoplasmosis from the records of deaths of the Mortality Information System of the Brazilian Ministry of Health. The rates were smoothed by the Local Empirical Bayesian model. The ...
Tópico(s): Travel-related health issues
2023 - Wiley | Tropical Medicine & International Health
Pedro Araújo, Alexandre Carvalho, Marta Pingarilho, DANIEL HENRIQUE DE FARIA, Raquel Pinho, José Manuel Martins Ferreira, Paula Proença, Sofia Nunes, Margarida Mouro, Eugénio Teófilo, Sofia Pinheiro, Fernando Maltêz, Maria José Manata, Isabel Germano, Joana Simões, Olga Costa, Rita Côrte‐Real, António Diniz, Margarida Serrado, Luís Caldeira, Nuno Janeiro, Guilhermina Gaião, José Melo‐Cristino, Kamal Mansinho, Teresa Baptista, Perpétua Gómes, Isabel Diogo, Rosário Serrão, C.F.S. Pinheiro, Carmo Koch, Fátima Monteiro, Anabela Susana de Sousa Gonçalves, Rui Sarmento e Castro, Helena Ramos, Joaquim Oliveira, José Saraiva da Cunha, Vanda Mota, Fernando Rodrigues, Raquel Tavares, Rita Silva, Fausto Roxo, MAURICIO MENEZES ABEN ATHAR IVO, José Poças, Bianca Branco Ascenção, Patrícia Pacheco, Micaela Caixeiro, Nuno Marques, Maria João Aleixo, Tiago de Carvalho Faria, Elisabete Gomes da Silva, Ricardo Correia de Abreu, I Neves, Ana Abecasis, Nuno S. Osório,
HIV-1 subtypes associate with differences in transmission and disease progression. Thus, the existence of geographic hotspots of subtype diversity deepens the complexity of HIV-1/AIDS control. The already high subtype diversity in Portugal seems to be increasing due to infections with sub-subtype A1 virus. We performed phylogenetic analysis of 65 A1 sequences newly obtained from 14 Portuguese hospitals and 425 closely related database sequences. 80% of the A1 Portuguese isolates gathered in a main ...
Tópico(s): Hepatitis C virus research
2019 - Nature Portfolio | Scientific Reports