Andrew Robson, Lucy Alexander, Marina McIntyre, Simon Barnes Chief Sports Writer, Gabriele Marcotti, James Burton Stewart, Lady Lloyd-Hughes, Robert Dawson Scott, Richard Whitehead, Matthew Syed, DJM, Joanna Taylor, Ruth Tenne, Greg Hurst Political Correspondent, Peter Lansley, Mark Souster, Dr N. A. Simmons, Philip Howard, David Lister Scotland Correspondent, David Chater, Joanna Walters, Doug Gratton, Joanna Bale, James Bone, James Ducker, Paul Cousins, Carol Sarler, Gabrielle Starkey, Carl Mortished, Amanda Andrews Media Business Correspondent, Sam Marlowe, Alex Griffiths, Geoff Brown, Gerald Davies, Irwin Stelzer, Joe Joseph, Ben Webster Transport Correspondent, Miriam M. Reik, Pat Gibson, David McVay, Matthew Weiner, Bert Mercer, Jane MacArtney, Valerie Elliott, Donald Hutera, Stewart Tendler Crime Correspondent, James Craigen, Dan Sabbagh Media Editor, Debra Craine, Hilary Weale, Jill Dupleix, Peter Mandelson, Dalya Alberge Arts Correspondent, Jane Clarke, Richard Ford Home Correspondent, Phil Gordon, Keith Pike, Chris campling, David Hands, Phil Evans, Jonathan Richards, Graham Keeley, Ron Lewis, Sholto Byrnes, Liz Chong, Greg Hurst, Angela Jameson, Danny Kelly, Martin Penner, Russell Kempson, Sally Jones, Oliver Kay, Sarah Vine, Lisa Armstrong, Neil Harman, Rick Broadbent, Tom Baldwin, Mark Henderson Science Correspondent, Sam Coates, David Lawrenson, Geoffrey Dean, Raymond Keene, Matthew Pryor, Matt Dickinson, George Caulkins, Kaveh Solhekol, Xan Rice, Mrs Danny Murphy, Robert Elms, Damian Whitworth, Mick Hume, Peter Dixon, Carolyn Asome, David Hands Rugby Correspondent, Tony Cascarino, Tom Dart, Paul Simons, Adam Fresco, Jonathan Clayton, Tim Hames, Ashling O'connor, Anjana Ahuja, Caitlin Moran, Alan Lee, Anthony Loyd, Dr Raphael Eban, Kaven Solhekol, Jeffery Ewener, Lewis Stuart, Martin Waller, Sherwin Hall, Danny Baker, Dr Hillary J. Shaw, Carl Mortished International Business Editor, Nigel Hawkes Health Editor, Mark Baldwin, Benedict Nightingale, Paul Larter, Dr Thomas Stuttaford, Stephen Dalton, Alan Wiley, Nicola Woolcock, David Powell, Bill Edgar, Alyson Rudd, Michael Evans, Mark Venables, Alan Lee Racing Correspondent, Alexandra Blair Education Correspondent, Owen Slot, Jonathan Djanogly, Edward Gorman Sailing Correspondent, Peter Klinger, Nick Meo, John Bassom, Anthony Browne and Rory Watson, Christopher Irvine, Roy Ramm,
... of the My Lai massacre in Vietnam Urbano Lazzaro Patisan who prevented Mussolini's escape from Italy ...
2006 - Gale Group | TDA
Babich Jw, F Keeling, Flower Ma, Lazzaro Repetto, Anthony Whitton, Sarah Fielding, Ann C. Fullbrook, Ott Rj, McCready Vr,
Tópico(s): Medical Imaging and Pathology Studies
1988 - Springer Science+Business Media | European Journal of Nuclear Medicine
Benjamin K. Henderson, Charlotte Gerhart, Steven A. Lane, E. A. Jensen, Steve Griffin, Anthony Lazzaro,
Launch acoustic and vibration loads have the potential to damage sensitive payloads within a payload fairing, often requiring more structural mass to withstand these loads than would otherwise be necessary to survive launch. Experiments demonstrating several vibro-acoustic mitigation technologies developed by AFRL/VS and its contractors flew on the Vibro-Acoustic Launch Protection Experiment 2 (VALPE-2) aboard a Terrier-Improved Orion sounding rocket from Wallops Island Flight Facility in August ...
Tópico(s): Aeroelasticity and Vibration Control
2003 - Acoustical Society of America | The Journal of the Acoustical Society of America
Taehee Kwak, Richard Lazzaro, Homayon Pournik, Daniel Ciaburri, Anthony J. Tortólani, Iosif Gulkarov,
Tópico(s): Tracheal and airway disorders
2011 - Springer Science+Business Media | Journal of Robotic Surgery
On Chen, Nripen Dontineni, Ghaith Nahlawi, Geetha P. Bhumireddy, Seol Young Han, Yakoub Katri, Iosif Gulkarov, Daniel Ciaburri, Anthony J. Tortólani, Richard Lazzaro, Terrence J. Sacchi, Joshua Socolow, John F. Heitner,
... Iosif M. Gulkarov, MD, Daniel G. Ciaburri, MD, Anthony J. Tortolani, MD, Richard S. Lazzaro, MD, Terrence J. Sacchi, MD, Joshua A. Socolow, ... Methodist Hospital Cardiovascular Magnetic Resonance Center, Brooklyn, NY. , Anthony J. TortolaniAnthony J. Tortolani From the New York Methodist Hospital Cardiovascular Magnetic Resonance Center, Brooklyn, NY. , Richard S. LazzaroRichard S. Lazzaro From the New York Methodist Hospital Cardiovascular Magnetic ...
Tópico(s): Cardiac Imaging and Diagnostics
2012 - Lippincott Williams & Wilkins | Circulation
Steven G. Friedman, Richard Lazzaro, Laurence N. Spier, Carmine G. Moccio, Anthony J. Tortólani,
Background. The purpose of this study was to compare the long-term results of Dacron and polytetrafluoroethylene (PTFE) aortic bifurcation grafts in a prospective randomized manner. Methods. Sixty patients with aortoiliac occlusive disease were randomized to receive Dacron or PTFE bifurcation grafts. Preoperative risk factors, perioperative blood loss and fluid requirements, and postoperative complications were compared. A mean follow-up of 57 months was achieved. Results. The immediate postoperative morbidity ...
Tópico(s): Aortic Disease and Treatment Approaches
1995 - Elsevier BV | Surgery
DONALD L. ROWE, P. A. Robinson, Christopher Rennie, Anthony Harris, Kim L. Felmingham, Ilario Lazzaro, Evian Gordon,
... L. ROWE, PETER A. ROBINSON, CHRISTOPHER J. RENNIE, ANTHONY W. HARRIS, KIM L. FELMINGHAM, ILARIO L. LAZZARO, and EVIAN GORDONDONALD L. ROWESchool of Physics, University ...
Tópico(s): Neural dynamics and brain function
2004 - Imperial College Press | Journal of Integrative Neuroscience
Pamela J. Marsh, Ilario Lazzaro, Barry Manor, Anthony Harris, Lea M. Williams, E. Gordon, D. Davidson,
Tópico(s): Attention Deficit Hyperactivity Disorder
2000 - Elsevier BV | Schizophrenia Research
Anthony Chau, Amanda Lazzaro, Ralph J. Mobbs, Charles Teo,
Chordomas in the clival-cervical region present challenges to the neurosurgical team due to their encroaching nature, proximity to critical neurovascular structures and often large size due to late presentation. This report illustrates the utility of a staged approach when confronted with such a pervasive tumour. We describe the adaptive combination of two approaches, the endoscopic endonasal transsphenoidal plus posterior cervical approaches, in the surgical management of a clival chordoma extending ...
Tópico(s): Oral and Maxillofacial Pathology
2010 - Elsevier BV | Journal of Clinical Neuroscience
Steven Griffin, Steven A. Lane, Anthony Lazzaro,
Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Tópico(s): Spacecraft Design and Technology
2008 - American Institute of Aeronautics and Astronautics | Journal of Spacecraft and Rockets
Tommaso Schirinzi, Giulia Maria Sancesario, Giulia Di Lazzaro, Simona Scalise, Vito Luigi Colona, Paola Imbriani, Nicola Biagio Mercuri, Sergio Bernardini, Anthony E. Lang, Antonio Pisani,
Tópico(s): Neurological disorders and treatments
2018 - Springer Science+Business Media | Journal of Neural Transmission
Charlotte Gerhart, Benjamin K. Henderson, Steve Griffin, Anthony Lazzaro, Michael E. Evert, Warren McCrary, Emil Ardelean,
The cost of performing any mission on orbit is a strong function of the cost of getting the mass into orbit and the mass of a spacecraft is driven by the launch loads that the components must be deigned to survive. Additionally, these design loads vary between launch vehicles so if circumstances arise that require a change in launch vehicle significant time and money can be spent in modifying and testing to meet different requirements. Technologies that reduce both the vibration and acoustic environments ...
Tópico(s): Spacecraft Design and Technology
2004 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Produção Nacional
Revisado por pares
Evian Gordon, Belinda J. Liddell, Kerri J. Brown, Richard A. Bryant, C. Richard Clark, Pritha Das, Carol Dobson‐Stone, Erin Falconer, Kim L. Felmingham, Gary Flynn, Justine M. Gatt, Anthony Harris, Daniel F. Hermens, Patrick J. Hopkinson, Andrew H. Kemp, Stacey A. Kuan, Illario Lazzaro, Jonson Moyle, Robert Paul, Chris Rennie, Peter R. Schofield, Thomas J. Whitford, Leanne M. Williams,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Genetic Associations and Epidemiology
2007 - Imperial College Press | Journal of Integrative Neuroscience
X. Litaudon, S. Abduallev, M. Abhangi, P. Abreu, Muhammad Afzal, K. M. Aggarwal, T. Ahlgren, J.-H. Ahn, L. Aho-Mantila, N. Aiba, Markus Airila, R. Albanese, V. Aldred, D. Alegre, E. Alessi, P. Aleynikov, A. Alfier, A. Alkseev, M. Allinson, B. Alper, E. Alves, G. Ambrosino, R. Ambrosino, L. Amicucci, V. N. Amosov, E. Andersson Sundén, M. Angelone, M. Anghel, C. Angioni, L. C. Appel, C. Appelbee, P. Arena, M. Ariola, H. Arnichand, S. Arshad, A. Ash, N. Ashikawa, V. Aslanyan, O. Asunta, F. Auriemma, Y. Austin, Lı̅ga Avotiņa, M. Axton, C.F. Ayres, M. Bacharis, A. Baciero, D. Baião, Sean Bailey, A. Baker, I. Balboa, M. Balden, N. Balshaw, R. Bament, Jeffrey W. Banks, Y. Baranov, M. Barnard, D. C. Barnes, M. Barnes, R. Barnsley, A. Baron-Wiecheć, L. Barrera Orte, M. Baruzzo, Vladimir A. Basiuk, M. Bassan, R. Bastow, Antônio M. Batista, P. Batistoni, R. Baughan, B. Bauvir, L.R. Baylor, Б. Базылев, J. Beal, P.S. Beaumont, M. Beckers, B. Beckett, A. Bécoulet, N. Bekris, M. Beldishevski, Kate Bell, F. Belli, M. Bellinger, É. Belonohy, N. Ben Ayed, N. A. Benterman, H. Bergsåker, J. Bernardo, M. Bernert, M. Berry, L. Bertalot, C. Beşliu, M. Beurskens, B. Bieg, J. Bielecki, T. M. Biewer, M. Bigi, P. Bílková, F. Binda, Andrea Bisoffi, João P. S. Bizarro, C. Björkas, Jeffrey L. Blackburn, Karin Blackman, T. Blackman, P. Blanchard, Peter Blatchford, V. Bobkov, A. Boboc, Г Й Боднар, O. Bogár, І. Bolshakova, T. Bolzonella, N. Bonanomi, F. Bonelli, J. Boom, J. Booth, D. Borba, D. Borodin, I. Borodkina, A. Botrugno, C. Bottereau, P. Boulting, C. Bourdelle, M. Bowden, C. Bower, C. Bowman, T. Boyce, C. Boyd, Helen Boyer, J. M. A. Bradshaw, V. Braic, R. Bravanec, B. N. Breǐzman, S. Brémond, P.D. Brennan, S. Breton, A. Brett, S. Brezinsek, M. Bright, M. Brix, Wouter Broeckx, M. Brombin, A. Brosławski, David Paul Brown, Matthew Brown, E. Bruno, J. Bucalossi, J.J.U. Buch, J. Buchanan, M. Buckley, R. Budny, H. Bufferand, Mel Bulman, N. Bulmer, P. Bunting, P. Buratti, A. Burckhart, Arturo Buscarino, Angela Busse, N. K. Butler, I. Bykov, J. Byrne, P. Cahyna, G. Calabrò, I. Calvo, Y. Camenen, P. Camp, D.C. Campling, J. Cane, B. Cannas, Adrian Capel, P. Card, A. Cardinali, P. Carman, M. Carr, D. Carralero, L. Carraro, B. B. Carvalho, I.S. Carvalho, P. Carvalho, F. J. Casson, C. Castaldo, N. Catarino, J. Caumont, F. Causa, R. Cavazzana, K. Cave-Ayland, M. Cavinato, M. Cecconello, S. Ceccuzzi, E. Cecil, Angelo Cenedese, R. Cesario, C. Challis, M. O. Chandler, D. Chandra, C. S. Chang, A. Chankin, S. C. Chapman, S. C. Chapman, M. Chernyshova, G. Chitarin, G. Ciraolo, D. Ćirić, J. Citrin, F. Clairet, E. Clark, M. W. Clark, R.B. Clarkson, D. Clatworthy, Christopher F. Clements, M. Cleverly, J.P. Coad, P. Coates, A. Cobalt, V. Coccorese, V. Cocilovo, S. Coda, R. Coelho, J.W. Coenen, I. Coffey, L. Colas, Stephen Collins, D. Conka, S. Conroy, N. J. Conway, D. Coombs, David Cooper, S. R. Cooper, Claudia Corradino, Y. Corre, G. Corrigan, S. Reyes-Cortes, D. Coster, A. S. Couchman, Matthew Cox, T. Craciunescu, S. Cramp, R. Craven, F. Crisanti, G. Croci, D. Croft, K. Crombé, R.D. Crowe, N. Cruz, G. Cseh, A. Cufar, A.L. Cullen, M. Curuia, A. Czarnecka, H. Dabirikhah, P. Dalgliesh, S. Dalley, J. Dankowski, D. Darrow, Owen J. Davies, W. Davis, C. Day, I.E. Day, M. De Bock, A. de Castro, E. de la Cal, E. de la Luna, G. De Masi, J.L. de Pablos, G. De Temmerman, G. De Tommasi, P.C. de Vries, K. Deakin, Jonathan H. B. Deane, F. Degli Agostini, R. Dejarnac, E. Delabie, N. den Harder, R. O. Dendy, J. Denis, P. Denner, S. Devaux, P. Devynck, F. Di Maio, A. Di Siena, C. Di Troia, P. Dincă, R. D’Incà, Bin Ding, T. Dittmar, H. Doerk, R.P. Doerner, T. Donné, S. Dorling, S. Dormido-Canto, S. Doswon, D. Douai, Paddy Doyle, A. Drenik, P. Drewelow, P. Drews,
The 2014–2016 JET results are reviewed in the light of their significance for optimising the ITER research plan for the active and non-active operation. More than 60 h of plasma operation with ITER first wall materials successfully took place since its installation in 2011. New multi-machine scaling of the type I-ELM divertor energy flux density to ITER is supported by first principle modelling. ITER relevant disruption experiments and first principle modelling are reported with a set of three disruption ...
IOP Publishing
Jennifer E. Davoren, Michelle R. Garnsey, Betty Pettersen, Michael A. Brodney, Jeremy R. Edgerton, Jean-Philippe Fortin, Sarah Grimwood, Anthony R. Harris, Stephen Jenkinson, Terry Kenakin, John T. Lazzaro, Che-Wah Lee, Susan M. Lotarski, Lisa Nottebaum, Steven V. O’Neil, Michael Popiolek, Simeon Ramsey, Stefanus J. Steyn, Catherine A. Thorn, Lei Zhang, Damien Webb,
Recent data demonstrated that activation of the muscarinic M1 receptor by a subtype-selective positive allosteric modulator (PAM) contributes to the gastrointestinal (GI) and cardiovascular (CV) cholinergic adverse events (AEs) previously attributed to M2 and M3 activation. These studies were conducted using PAMs that also exhibited allosteric agonist activity, leaving open the possibility that direct activation by allosteric agonism, rather than allosteric modulation, could be responsible for the adverse ...
Tópico(s): Pharmacological Receptor Mechanisms and Effects
2017 - American Chemical Society | Journal of Medicinal Chemistry
Jennifer E. Davoren, Steven V. O’Neil, Dennis P. Anderson, Michael A. Brodney, Lois K. Chenard, Keith Dlugolenski, Jeremy R. Edgerton, Michael Green, Michelle R. Garnsey, Sarah Grimwood, Anthony R. Harris, Gregory W. Kauffman, Erik LaChapelle, John T. Lazzaro, Che‐Wah Lee, Susan M. Lotarski, Deane M. Nason, R. Scott Obach, Veronica Reinhart, Romelia Salomón–Ferrer, Stefanus J. Steyn, Damien Webb, Jiangli Yan, Lei Zhang,
Selective activation of the M1 receptor via a positive allosteric modulator (PAM) is a new approach for the treatment of the cognitive impairments associated with schizophrenia and Alzheimer's disease. A novel series of azaindole amides and their key pharmacophore elements are described. The nitrogen of the azaindole core is a key design element as it forms an intramolecular hydrogen bond with the amide N-H thus reinforcing the bioactive conformation predicted by published SAR and our homology model. ...
Tópico(s): Neuroscience and Neuropharmacology Research
2015 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Parvin Shahrestani, Elizabeth G. King, Reza Ramezan, Mark Phillips, Melissa Riddle, Marisa Thornburg, Zachary Greenspan, Yonathan Estrella, Kelly Garcia, Pratik Chowdhury, Glen Malarat, Ming Zhu, Susan M. Rottshaefer, Stephen P. Wraight, Michael H. Griggs, John D. Vandenberg, Anthony D. Long, Andrew G. Clark, Brian P. Lazzaro,
Abstract Little is known about the genetic architecture of antifungal immunity in natural populations. Using two population genetic approaches, quantitative trait locus (QTL) mapping and evolve and resequence (E&R), we explored D. melanogaster immune defense against infection with the fungus Beauveria bassiana. The immune defense was highly variable both in the recombinant inbred lines from the Drosophila Synthetic Population Resource used for our QTL mapping and in the synthetic outbred populations ...
Tópico(s): Invertebrate Immune Response Mechanisms
2021 - Genetics Society of America | G3 Genes Genomes Genetics
Tópico(s): Merger and Competition Analysis
2004 - Cleveland State University College of Law | Cleveland State law review
Belinda J. Liddell, Robert Paul, Martijn Arns, Norman Gordon, Matthew Kukla, DONALD L. ROWE, Nicholas R. Cooper, Jonson Moyle, Leanne M. Williams,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Diet and metabolism studies
2007 - Imperial College Press | Journal of Integrative Neuroscience
MELINDA D. VELTMEYER, Alexander C. McFarlane, Richard A. Bryant, Therese Mayo, Evian Gordon, C. Richard Clark,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Stress Responses and Cortisol
2006 - Imperial College Press | Journal of Integrative Neuroscience
Hannah A.D. Keage, Christopher Clark, Daniel F. Hermens, Michael Kohn, Simon Clarke, Leanne M. Williams, David P. Crewther, Chris Lamb, Evian Gordon,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Functional Brain Connectivity Studies
2006 - Imperial College Press | Journal of Integrative Neuroscience
Andrew H. Kemp, Blossom C. M. Stephan, Patrick J. Hopkinson, Alexander Sumich, Robert Paul, C. Richard Clark, Evian Gordon, Richard A. Bryant, Leanne M. Williams,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Heart Rate Variability and Autonomic Control
2005 - Imperial College Press | Journal of Integrative Neuroscience
MELINDA D. VELTMEYER, C. Richard Clark, Alexander C. McFarlane, Kim L. Felmingham, Richard A. Bryant, Evian Gordon,
... FALCONER, KIM FELMINGHAM, GARY FLYNN, JUSTINE M. GATT, ANTHONY HARRIS, DANIEL F. HERMENS, PATRICK J. HOPKINSON, ANDREW H. KEMP, STACEY A. KUAN, ILLARIO LAZZARO, JONSON MOYLE, ROBERT H. PAUL, CHRIS J. RENNIE, ...
Tópico(s): Anesthesia and Neurotoxicity Research
2005 - Imperial College Press | Journal of Integrative Neuroscience
Produção Nacional
Revisado por pares
Silvia Bonoli, A. Marín-Franch, J. Varela, H. Vázquez Ramió, L. Raul Abramo, A. J. Cenarro, Renato A. Dupke, J. M. Vı́lchez, D. Cristóbal-Hornillos, R. M. González Delgado, C. Hernández‐Monteagudo, C. López-Sanjuán, D. Muniesa, T. Civera, A. Ederoclite, A. Hernán-Caballero, Valerio Marra, P. O. Baqui, A. Cortesi, E. S. Cypriano, S. Daflon, A. L. de Amorim, L. A. Díaz-García, J. M. Diego, G. Martínez-Solaeche, E. Pérez, Vinicius M. Placco, Francisco Prada, C. Queiroz, J. S. Alcaniz, A. Álvarez-Candal, J. Cepa, Antonio L. Maroto, F. Roig, B.B. Siffert, K. Taylor, N. Benı́tez, M. Moles, L. Sodré, S. Carneiro, C. Mendes de Oliveira, Élcio Abdalla, Raúl E. Angulo, Miguel Aparicio Resco, A. Balaguera-Antolínez, Fernando Ballesteros, D. Brito-Silva, Tom Broadhurst, E. R. Carrasco, Tiago Castro, R. Cid Fernandes, P. Coelho, R. B. de Melo, L. Doubrawa, A. Fernández-Soto, Fabrício Ferrari, A. Finoguenov, R. García-Benito, J. Iglésias-Páramo, Y. Jiménez-Teja, Francisco-Shu Kitaura, J. Laur, P. A. A. Lopes, Geferson Lucatelli, Vicent J. Martı́nez, M. Maturi, Roderik Overzier, C. Pigozzo, Miguel Quartin, J. E. Rodríguez-Martín, Vincenzo Salzano, A. Tamm, Elmo Tempel, Keiichi Umetsu, L. Valdivielso, Rodrigo von Marttens, Adi Zitrin, M. C. Díaz-Martín, G. López-Alegre, Á. López-Sáinz, A. Yanes-Díaz, F. Rueda-Teruel, S. Rueda-Teruel, Javier Abril Ibáñez, J. L. Antón Bravo, R. Ferrer, Samuel Bielsa, J. M. Casino, J. Castillo Castellanos, Sergio Chueca, L. Cuesta, J. Garzarán Calderaro, R. Iglesias-Marzoa, C. Íñiguez, J. L. Lamadrid Gutierrez, F. López-Martínez, David Lozano-Pérez, N. Maícas Sacristán, Enrique Luís Molina-Ibáñez, Alberto Moreno-Signes, S. Rodríguez Llano, M. Royo Navarro, V. Tilve Rua, U. Andrade, E. J. Alfaro, S. Akras, P. Arnalte-Mur, B. Ascaso, C. E. Barbosa, José Beltrán Jiménez, Micol Benetti, Carlos A. P. Bengaly, Armando Bernui, José J. Blanco-Pillado, M. Borges Fernandes, Joel N. Bregman, Gustavo Bruzual, Giorgio Calderone, J. M. Carvano, Luciano Casarini, Jonás Chaves-Montero, Ana L. Chies-Santos, G C Carvalho, Paola Dimauro, S. Duarte Puertas, David Figueruelo, J. I. González‐Serrano, M. A. Guerrero, Siddhartha Gurung-López, D. Herranz, Marc Huertas-Company, Jimmy A. Irwin, David Izquierdo–Villalba, A. Kanaan, C. Kehrig, C. C. Kirkpatrick, J. Lim, Amanda R. Lopes, R. Lopes de Oliveira, A. Marcos-Caballero, David Martínez‐Delgado, E. Martínez-González, G. Martínez-Somonte, Nícolas O. L. de Oliveira, Álvaro Orsi, Mariana Penna-Lima, Ribamar R. R. Reis, Daniele Spinoso, Shinji Tsujikawa, P. Vielva, A Z Vitorelli, Jun‐Qing Xia, Haibo Yuan, A. Arroyo-Polonio, M. L. L. Dantas, Carlos Andrés Galarza, D. R. Gonçalves, R. S. Gonçalves, J. E. Gonzalez, Anthony H. Gonzalez, N. Greisel, F. Jiménez-Esteban, Ricardo G. Landim, D. Lazzaro, G. Magris, Rogério Monteiro-Oliveira, C. B. Pereira, M. J. Rebouças, J. M. Rodríguez-Espinosa, S. Santos da Costa, Eduardo Telles,
The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) will soon start to scan thousands of square degrees of the northern extragalactic sky with a unique set of $56$ optical filters from a dedicated $2.55$m telescope, JST, at the Javalambre Astrophysical Observatory. Before the arrival of the final instrument (a 1.2 Gpixels, 4.2deg$^2$ field-of-view camera), the JST was equipped with an interim camera (JPAS-Pathfinder), composed of one CCD with a 0.3deg$^2$ field-of-view and ...
Tópico(s): Stellar, planetary, and galactic studies
2021 - EDP Sciences | Astronomy and Astrophysics
Jennifer E. Davoren, Che‐Wah Lee, Michelle R. Garnsey, Michael A. Brodney, Jason Cordes, Keith Dlugolenski, Jeremy R. Edgerton, Anthony R. Harris, Christopher J. Helal, Stephen Jenkinson, Gregory W. Kauffman, Terrence Kenakin, John T. Lazzaro, Susan M. Lotarski, Yuxia Mao, Deane M. Nason, Carrie A. Northcott, Lisa Nottebaum, Steven V. O’Neil, Betty Pettersen, Michael Popiolek, Veronica Reinhart, Romelia Salomón–Ferrer, Stefanus J. Steyn, Damien Webb, Lei Zhang, Sarah Grimwood,
It is hypothesized that selective muscarinic M1 subtype activation could be a strategy to provide cognitive benefits to schizophrenia and Alzheimer's disease patients while minimizing the cholinergic side effects observed with nonselective muscarinic orthosteric agonists. Selective activation of M1 with a positive allosteric modulator (PAM) has emerged as a new approach to achieve selective M1 activation. This manuscript describes the development of a series of M1-selective pyridone and pyridine ...
Tópico(s): Computational Drug Discovery Methods
2016 - American Chemical Society | Journal of Medicinal Chemistry
P. Di Lazzaro, Anthony C. Atkinson, Paola Iacomussi, Marco Riani, Marco Ricci, Peter Wadhams,
We review the sampling and results of the radiocarbon dating of the archaeological cloth known as the Shroud of Turin, in the light of recent statistical analyses of both published and raw data. The statistical analyses highlight an inter-laboratory heterogeneity of the means and a monotone spatial variation of the ages of subsamples that suggest the presence of contaminants unevenly removed by the cleaning pretreatments. We consider the significance and overall impact of the statistical analyses ...
Tópico(s): Ancient Egypt and Archaeology
2020 - Multidisciplinary Digital Publishing Institute | Entropy
Iosif Gulkarov, Daniel Ciaburri, Anthony J. Tortólani, Richard Lazzaro,
Tópico(s): Tracheal and airway disorders
2012 - Springer Science+Business Media | Journal of Robotic Surgery
B. Case Law Interpreting the Free Exercise Clause.577 C. BFRA and City of Boeme v. Flores.580 D. RLUIPA.582 II. The Judicial Interpretation of RLUIPA's Equal Terms Provision.584 A. The Eleventh Circuit.585 B. The Seventh Circuit.590 C. The Third Circuit.592 III. Why the Midrash Approach Provides the Best Interpretive Framework for the Analysis of Equal Terms Challenges.595 A. The Circuit Split.597 B. The Similarly Situated Secular Comparator Requirement.599 1. The Third Circuit's Fears.599 2. Principles ...
Tópico(s): Legal Cases and Commentary
2010 - University of Pennsylvania Law School | University of Pennsylvania Law Review
A.L. Copley, G. W. Scott Blair,
... 1686, a number of successive observers, such as Anthony van Leeuwenhoek, Lazzaro SpaUanzani and Albrecht von HaIler gave descriptions of ...
1962 - IOS Press | Biorheology
Christopher Keefer, George Chang, Anthony Carlo, Jonathan J. Novak, Michael J. Banker, Jackie Carey, Julie Cianfrogna, Heather Eng, Caitlin Jagla, Nathaniel Johnson, Rhys Jones, Samantha Jordan, Sarah Lazzaro, Jianhua Liu, R. Scott Obach, Keith Riccardi, David A. Tess, John P. Umland, Jillian Racich, Manthena V. S. Varma, Ravi Visswanathan, Li Di,
Human liver microsomes (HLM) and human hepatocytes (HHEP) are two common in vitro systems used in metabolic stability and inhibition studies. The comparison between the assays using the two systems can provide mechanistic insights on the interplay of metabolism, passive permeability and transporters. This study investigated the critical factors impacting the unbound intrinsic clearance (CLint,u) and IC50 of CYP3A inhibition between HLM and HHEP. The HLM/HHEP CLint,u ratio and HHEP/HLM IC50 ratio are ...
Tópico(s): Liver Disease Diagnosis and Treatment
2020 - Elsevier BV | European Journal of Pharmaceutical Sciences