Honoré-Antoine Richaud-Martelly,
"Représentée, pour la première fois, sur le théâtre de la République, ľan troisième, et remise au théâtre de la Cité-Variétés, le premier thermidor, an ...
1799 - Gale Group | NCCO Corvey
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Tópico(s): Historical Influence and Diplomacy
1949 - University of Chicago Press | Journal of the Warburg and Courtauld Institutes
Juan Manuel Peñaloza‐Ramírez, Antonio González‐Rodríguez, Luis Mendoza‐Cuenca, Henri Caron, Antoine Kremer, Ken Oyama,
Interspecific gene flow can occur in many combinations among species within the genus Quercus, but simultaneous hybridization among more than two species has been rarely analysed. The present study addresses the genetic structure and morphological variation in a triple hybrid zone formed by Q. hypoleucoides, Q. scytophylla and Q. sideroxyla in north-western Mexico. A total of 247 trees from ten reference and 13 presumed intermediate populations were characterized using leaf shape variation and geometric ...
Tópico(s): Plant tissue culture and regeneration
2010 - Oxford University Press | Annals of Botany
Céline Latouche-Hallé, A. Ramboer, Éric Bandou, Henri Caron, Antoine Kremer,
Tópico(s): Plant and animal studies
2003 - Springer Nature | Heredity
Émilie Caron, Antoine Gross, Jean‐Pierre Liautard, Jacques Dornand,
Brucella species can establish themselves and cause disease in humans, but the mechanisms by which brucellae evade the antibacterial defenses of their host remain largely unknown. We have previously reported that, unlike Escherichia coli K12, intracellular pathogens from the genus Brucella survive and multiply within U937-derived phagocytes, and live Brucella organisms failed to induce TNF-alpha release upon infection. Moreover, exogenously added TNF-alpha restricted intracellular growth of Brucella ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
1996 - American Association of Immunologists | The Journal of Immunology
Céline Latouche-Hallé, A. Ramboer, Éric Bandou, Henri Caron, Antoine Kremer,
Abstract Outcrossing rates, pollen dispersal and male mating success were assessed in Dicorynia guianensis Amshoff, a neotropical tree endemic to the Guiana shield. All adult trees within a continuous area of 40 ha ( n = 157) were mapped, and were genotyped with six microsatellite loci. In addition, progenies were genotyped from 22 mature trees. At the population level, the species was mostly outcrossing ( t m = 0.89) but there was marked variation among individuals. One tree exhibited mixed mating, confirming ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2004 - Wiley | Molecular Ecology
P. Caron, Antoine Tabarin, Muriel Cogne, Philippe Chanson, P Jaquet,
Intramuscular injections of 30mg slow-release (SR) lanreotide (every 10 to 14 days) are an effective treatment in acromegalic patients. Because of an ongoing need to assess the efficacy and the tolerance of a new formulation of a depot preparation of lanreotide, we have evaluated prospectively GH profiles following withdrawal of 30mg slow-release lanreotide in a cohort of acromegalic patients.Fifty-one acromegalic patients, controlled during long-term 30mg SR lanreotide treatment (GH: 1.44 +/- 0.64 microgram/ ...
Tópico(s): Adrenal and Paraganglionic Tumors
2000 - Oxford University Press | European Journal of Endocrinology
Estelle Louiset, Céline Duparc, Jacques Young, Sylvie Renouf, Milène Tetsi Nomigni, Isabelle Boutelet, Rossella Libé, Zakariae Bram, Lionel Groussin, Philippe Caron, Antoine Tabarin, F. Grünenberger, Sophie Christin-Maître, Xavier Bertagna, Jean‐Marc Kuhn, Youssef Anouar, Jérôme Bertherat, Hervé Lefèbvre,
Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing's syndrome. In this form of hyperplasia, hypersecretion of cortisol suppresses the release of corticotropin by pituitary corticotrophs, which results in low plasma corticotropin levels. Thus, the disease has been termed corticotropin-independent macronodular adrenal hyperplasia. We examined the abnormal production of corticotropin in these hyperplastic adrenal glands.We obtained specimens of hyperplastic macronodular ...
Tópico(s): Adrenal and Paraganglionic Tumors
2013 - Massachusetts Medical Society | New England Journal of Medicine
Emmanuel Chazard, Grégoire Ficheur, Alexandre Caron, Antoine Lamer, Julien Labreuche, Marc Cuggia, Michaël Génin, Guillaume Bouzillé, Alain Duhamel,
Secondary use of clinical structured data takes an important place in healthcare research. It was first described by Fayyad as "knowledge discovery in databases". Feature extraction is an important phase but received little attention. The objectives of this paper are: 1) to propose an updated representation of data reuse in healthcare, 2) to illustrate methods and objectives of feature extraction, and 3) to discuss the place of domain-specific knowledge.an updated representation is proposed. Then, ...
Tópico(s): Artificial Intelligence in Healthcare
2018 - IOS Press | Studies in health technology and informatics
Chrystelle Colas, Valérie Bonadona, Stéphanie Baert‐Desurmont, Delphine Bonnet, Florence Coulet, Marion Dhooge, Jean‐Christophe Saurin, Audrey Remenieras, Yves‐Jean Bignon, Olivier Caron, Antoine De Pauw, Marie‐Pierre Buisine, Bruno Buecher,
Tópico(s): Colorectal and Anal Carcinomas
2020 - Elsevier BV | European Journal of Medical Genetics
Arnaud Bayle, Laïla Belcaid, Mihaela Aldea, Damien Vasseur, Florent Peyraud, Claudio Nicotra, Arthur Géraud, Madona Sakkal, L. Seknazi, Luigi Cerbone, Félix Blanc‐Durand, Julien Hadoux, F. Mosele, Marco Tagliamento, Alice Bernard‐Tessier, Benjamin Verret, Cristina Smolenschi, R. Clodion, Nathalie Auger, Paola Romano, Anas Gazzah, Maud Ngo Camus, Jean‐Baptiste Micol, Olivier Caron, Antoine Hollebecque, Yohann Loriot, Benjamin Besse, Ludovic Lacroix, Etienne Rouleau, Santiago Ponce, Jean‐Charles Soria, Fabrice Barlési, Fabrice André, Antoîne Italiano,
Tópico(s): Genetic factors in colorectal cancer
2023 - Elsevier BV | Annals of Oncology
Étienne Caron, Antoine Gabrion, Matthieu Ehlinger, Nicolas Verdier, Brice Rubens-Duval, Thomas Néri, Pierre Martz, Sophie Putman, Gilles Pаsquier,
Hinged total knee arthroplasty (TKA) implants are a commonly used option during revision or even primary surgery, but their complications are not as well known, due to the rapid adoption of gliding implants. The literature is inconsistent on this topic, with studies having a small sample size, varied follow-up duration and very different indications. This led us to carry out a large multicentre study with a minimum follow-up of 5 years to evaluate the complications after hinged TKA in a non-tumoral ...
Tópico(s): Orthopedic Infections and Treatments
2021 - Elsevier BV | Orthopaedics & Traumatology Surgery & Research
François Rheault, Kurt G. Schilling, Alex Valcourt‐Caron, Antoine Théberge, Charles Poirier, Gabrielle Grenier, Guido I. Guberman, John P. Begnoche, Jon Haitz Legarreta, Leon Y. Cai, Maggie Roy, Manon Edde, Marco Pérez Cáceres, Mario Ocampo‐Pineda, Noor Al‐Sharif, Philippe Karan, Pietro Bontempi, Sami Obaïd, Sara Bosticardo, Simona Schiavi, Viljami Sairanen, Alessandro Daducci, Laurie E. Cutting, Laurent Petit, Maxime Descoteaux, Bennett A. Landman,
Abstract The segmentation of brain structures is a key component of many neuroimaging studies. Consistent anatomical definitions are crucial to ensure consensus on the position and shape of brain structures, but segmentations are prone to variation in their interpretation and execution. White‐matter (WM) pathways are global structures of the brain defined by local landmarks, which leads to anatomical definitions being difficult to convey, learn, or teach. Moreover, the complex shape of WM pathways ...
Tópico(s): Fetal and Pediatric Neurological Disorders
2022 - Wiley | Human Brain Mapping
Philippe Caron, Antoine Bennet, Monique Plantavid, Jean‐Pierre Louvet,
Caron PJ, Bennet AP, Plantavid MM, Louvet J-P. Luteinizing hormone secretory pattern before and after removal of Leydig cell tumor of the testis. Eur J Endocrinol 1994;131:156–9. ISSN 0804–4643 We studied the luteinizing hormone (LH) secretory pattern in three patients, aged 30, 23 and 43 years, with gynecomastia due to Leydig cell tumor of the testis, before and 6 months after unilateral orchidectomy. The results were compared to those of 11 normal fertile controls aged 20–35 years. Blood sampling ...
Tópico(s): Sexual Differentiation and Disorders
1994 - Oxford University Press | European Journal of Endocrinology
Antoine Caron, Christian Braud, Claude Bunel, Michel Vert,
The pendant benzyl groups of benzyl-protected poly(carboxylic acid) can be cleaved totally or partially by Pd/C-catalysed hydrogenolysis. Partial hydrogenolysis has been suspected to yield copolymers in which acid and acid benzyl ester units are not distributed at random. In order to demonstrate the blocky structure of such copolymers, five samples of poly(benzyl malolactonate), a degradable functional polyester, have been hydrogenolysed under different conditions. It has been found that hydrogenolysis ...
Tópico(s): Polymer crystallization and properties
1990 - Elsevier BV | Polymer
Nathalie Boutonnet‐Fagegaltier, J. Ménégotto, A. Lamure, Hélène Duplaa, Antoine Caron, C. Lacabanne, Michel Bauer,
Two crystalline forms and the amorphous state of irbesartan, a pharmaceutical drug chosen as a model, were analyzed by Thermally Stimulated Current (TSC) spectroscopy, a powerful technique currently used in polymer science to investigate the molecular dynamics of heterogeneous and complex materials. Whereas no specific dielectric response was noted for the B crystalline form, the A form of irbesartan exhibited molecular motions localized inside its channel structure. The dynamics involved in the ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2002 - Elsevier BV | Journal of Pharmaceutical Sciences
Fabien Pierron, Sarah Bureau du Colombier, Audrey Moffett, Antoine Caron, Laurent Peluhet, Guillemine Daffe, Patrick Lambert, Pierre Élie, Pierre Labadie, Hélène Budzinski, Sylvie Dufour, Patrice Couture, Magalie Baudrimont,
There is increasing evidence that pollutants may cause diseases via epigenetic modifications. Epigenetic mechanisms such as DNA methylation participate in the regulation of gene transcription. Surprisingly, epigenetics research is still limited in ecotoxicology. In this study, we investigated whether chronic exposure to contaminants experienced by wild female fish (Anguilla anguilla) throughout their juvenile phase can affect the DNA methylation status of their oocytes during gonad maturation. Thus, ...
Tópico(s): Demographic Trends and Gender Preferences
2014 - American Chemical Society | Environmental Science & Technology
Antoine Caron, Augusto C. Hernandez‐Perez, Shawn K. Collins,
A continuous flow UV light reactor has been constructed using commercially available equipment, and its efficiency was demonstrated by performing a photocyclodehydrogenation reaction to prepare carbazole derivatives of the drug carprofen.
Tópico(s): Oxidative Organic Chemistry Reactions
2014 - American Chemical Society | Organic Process Research & Development
Lucie Baillon, Fabien Pierron, Raphaël Coudret, Eric Normendeau, Antoine Caron, Laurent Peluhet, Pierre Labadie, Hélène Budzinski, Gilles Durrieu, Jérôme Sarraco, Pierre Élie, Patrice Couture, Magalie Baudrimont, Louis Bernatchez,
Identifying specific effects of contaminants in a multi-stress field context remain a challenge in ecotoxicology. In this context, “omics” technologies, by allowing the simultaneous measurement of numerous biological endpoints, could help unravel the in situ toxicity of contaminants. In this study, wild Atlantic eels were sampled in 8 sites presenting a broad contamination gradient in France and Canada. The global hepatic transcriptome of animals was determined by RNA-Seq. In parallel, the contamination ...
Tópico(s): Selenium in Biological Systems
2014 - Springer Science+Business Media | Ecotoxicology
Augusto C. Hernandez‐Perez, Antoine Caron, Shawn K. Collins,
Abstract An evaluation of both a visible‐light‐ and UV‐light‐mediated synthesis of carbazoles from various triarylamines with differing electronic properties under continuous‐flow conditions has been conducted. In general, triarylamines bearing electron‐rich groups tend to produce higher yields than triarylamines possessing electron‐withdrawing groups. The incorporation of nitrogen‐based heterocycles, as well as halogen‐containing arenes in carbazole skeletons, was well tolerated, and often synthetically ...
Tópico(s): Sulfur-Based Synthesis Techniques
2015 - Wiley | Chemistry - A European Journal
A. Barateau, Christopher Garlopeau, Audrey Cugny, B. Henriques de Figueiredo, Charles Dupin, J. Caron, Mikaël Antoine,
We aimed to identify the most accurate combination of phantom and protocol for image value to density table (IVDT) on volume-modulated arc therapy (VMAT) dose calculation based on kV-Cone-beam CT imaging, for head and neck (H&N) and pelvic localizations.Three phantoms (Catphan(®)600, CIRS(®)062M (inner phantom for head and outer phantom for body), and TomoTherapy(®) "Cheese" phantom) were used to create IVDT curves of CBCT systems with two different CBCT protocols (Standard-dose Head and Standard Pelvis). ...
Tópico(s): Radiation Dose and Imaging
2015 - Elsevier BV | Physica Medica
Antoine Caron, Maikel Rosabal, Ophélie Drevet, Patrice Couture, Peter G. C. Campbell,
Abstract Biomolecules involved in handling cytosolic metals in the liver of the yellow perch ( Perca flavescens ) were characterized in juvenile fish collected from 4 lakes constituting metal contamination gradients. Using size‐exclusion liquid chromatography coupled to an inductively coupled mass spectrometer, we determined metal distributions among ligands of different molecular weights in the cytosol, before and after a heat denaturation step designed to isolate metallothionein‐like peptides and ...
Tópico(s): Heavy metals in environment
2017 - Wiley | Environmental Toxicology and Chemistry
Clémentine Minozzi, Antoine Caron, Jean‐Christophe Grenier‐Petel, Jeffrey Santandrea, Shawn K. Collins,
A library of 50 copper-based complexes derived from bisphosphines and diamines was prepared and evaluated in three mechanistically distinct photocatalytic reactions. In all cases, a copper-based catalyst was identified to afford high yields, where new heteroleptic complexes derived from the bisphosphine BINAP displayed high efficiency across all reaction types. Importantly, the evaluation of the library of copper complexes revealed that even when photophysical data is available, it is not always ...
Tópico(s): Asymmetric Hydrogenation and Catalysis
2018 - Wiley | Angewandte Chemie International Edition
Nastassia Urien, Sophie Cooper, Antoine Caron, Helga Sonnenberg, Lisa D. Rozon‐Ramilo, Peter G. C. Campbell, Patrice Couture,
In the present study, we examined the subcellular distribution of metals and metalloids (As, Cd, Cu, Se and Zn) in the liver and gonads of wild white suckers (Catostomus commersonii) collected downstream from a metal mining operation (exposure area) and in a reference area. Metal partitioning among potentially metal-sensitive fractions (heat-denatured proteins (HDP), mitochondria and microsomes) and potentially biologically detoxified fractions (heat-stable proteins (HSP) and metal-rich granules) within ...
Tópico(s): Mercury impact and mitigation studies
2018 - Elsevier BV | Aquatic Toxicology
Clémentine Minozzi, Antoine Caron, Jean‐Christophe Grenier‐Petel, Jeffrey Santandrea, Shawn K. Collins,
Abstract A library of 50 copper‐based complexes derived from bisphosphines and diamines was prepared and evaluated in three mechanistically distinct photocatalytic reactions. In all cases, a copper‐based catalyst was identified to afford high yields, where new heteroleptic complexes derived from the bisphosphine BINAP displayed high efficiency across all reaction types. Importantly, the evaluation of the library of copper complexes revealed that even when photophysical data is available, it is not ...
Tópico(s): Radical Photochemical Reactions
2018 - Wiley | Angewandte Chemie
Antoine Caron, Émilie Morin, Shawn K. Collins,
A bifunctional copper-based photocatalyst has been prepared that employs a pyrazole-pyridine ligand incorporating a sulfonamide moiety that functions as an intramolecular hydrogen-bond donor for a photochemical PCET process. In typical reductive PCET processes, the photocatalyst and H-bond donor must have an appropriate redox potential and pKa, respectively, to promote the PCET. When working in concert in a bifunctional catalyst such as Cu(pypzs)(BINAP)BF4, the pKa of the H-bond donor can have an ...
Tópico(s): Sulfur-Based Synthesis Techniques
2019 - American Chemical Society | ACS Catalysis
Mélissa Khadra, Antoine Caron, Dolors Planas, Dominic E. Ponton, Maikel Rosabal, Marc Amyot,
Mercury (Hg) is a trace element of particular concern since it is ubiquitous in the environment and because its methylated form (MeHg) readily bioaccumulates and biomagnifies in food webs. This latter process leads to elevated Hg concentrations in fish and may thus induce toxicity. Maternal transfer of bioaccumulated contaminants to offspring is a suggested mechanism of impaired reproductive success in fish. The purpose of this study was to assess the toxicity potential of Hg during maternal transfer ...
Tópico(s): Selenium in Biological Systems
2019 - Elsevier BV | The Science of The Total Environment
Pierre‐Yves Cardon, Gaëlle Triffault‐Bouchet, Antoine Caron, Maikel Rosabal, Claude Fortin, Marc Amyot,
The demand for rare earth elements (REEs) has increased since the 1990s leading to the development of many mining projects worldwide. However, less is known about how organisms can handle these metals in natural aquatic systems. Through laboratory experiments, we assessed the chronic toxicity and subcellular fractionation of yttrium (Y), one of the four most abundant REEs, in three freshwater organisms commonly used in aquatic toxicology: Daphnia magna, Chironomus riparius, and Oncorhynchus mykiss. ...
Tópico(s): Analytical chemistry methods development
2019 - American Chemical Society | ACS Omega
Éric Godin, Jeffrey Santandrea, Antoine Caron, Shawn K. Collins,
Copper-catalyzed cross-coupling of thiols and bromoalkynes affords a mild, rapid, and selective Csp–S coupling with broad scope, enabling the use of aryl-, alkyl-, and silyl-substituted alkynyl coupling partners (38 total examples, 50–99% yields). Importantly, the method enables the preparation of difficult-to-access bis-heteroatom-functionalized (S,S-, S,P-, and S,N-) alkynes.
Tópico(s): Click Chemistry and Applications
2020 - American Chemical Society | Organic Letters
Dominic E. Ponton, Antoine Caron, Landis Hare, Peter G. C. Campbell,
Yellow perch (Perca flavescens) collected from 11 lakes in the Canadian mining regions of Sudbury (Ontario) and Rouyn-Noranda (Quebec) display wide ranges in the concentrations of cadmium (Cd), nickel (Ni), selenium (Se), and thallium (Tl) in their livers. To determine if these trace elements, as well as copper (Cu) and zinc (Zn), are causing oxidative stress in these fish, we measured three biochemical indicators (glutathione (GSH), glutathione disulfide (GSSG) and thiobarbituric acid-reactive substances (TBARS)) ...
Tópico(s): Mercury impact and mitigation studies
2016 - Elsevier BV | Environmental Pollution