Antonio J. Amor, Irene Halperín, Rocı́o Alfayate, Victoria M. Borrás, A. Escribano, Cintia González, Antonio Gutiérrez, Montserrat Maurí, P Rubio Pérez, Antonio Picó, Irene Vourliotaki, Josep Oriola,
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2014 - Springer Science+Business Media | HORMONES
María Eugenia Parrón-Rubio, Francisca Pérez-García, Antonio González-Herrera, María Dolores Rubio Cintas,
Concrete consumption greatly exceeds the use of any other material in engineering. This is due to its good properties as a construction material and the availability of its components. Nevertheless, the present worldwide construction increases and the high-energy consumption for cement production means a high environmental impact. On the other hand, one of the main problems in the iron and steel industry is waste generation and byproducts that must be properly processed or reused to promote environmental ...
Tópico(s): Graphite, nuclear technology, radiation studies
2018 - Multidisciplinary Digital Publishing Institute | Materials
la principal finalidad de estas notas es la de contribuir a delimitar los diferentes planteamientos de la motivacion y satisfaccion laboral a lo largo de estas ultimas decadas. se trata de hacer un recorrido por las diferentes perspectivas y destacar las que mas se han interesado por aspectos mas ligados al campo de las relaciones sociales, sin animo de reivindicar un estatuto de independencia para los enfoques sociologicos dado el caracter interdisciplinar que por naturaleza tiene este fenomeno. ...
Tópico(s): Organizational Management and Innovation
1997 - Centro de Investigaciones Sociológicas | Revista Española de Investigaciones Sociológicas
María Eugenia Parrón-Rubio, Francisca Pérez-García, Antonio González-Herrera, Miguel José Oliveira, María Dolores Rubio Cintas,
A circular economy is a current tenet that must be implemented in the field of construction. That would imply the study of the possibilities of the use of waste generated, for obtaining materials the used in construction as replacements for the raw material used. One of these possibilities is the substitution of the cement by slag, which contributes to the reduction of cement consumption, decreasing CO2 emissions, while solving a waste management problem. In the present paper, different types of ...
Tópico(s): Innovations in Concrete and Construction Materials
2019 - Multidisciplinary Digital Publishing Institute | Materials
Eva M. Monsalve, Miguel Ángel Sebastián Pérez, Antonio Rubio, María José Ruiz‐Hidalgo, Victoriano Baladrón, José Javier García‐Ramírez, Juan Carlos Gómez, Jorge Laborda, María José Guerra Palmero,
Abstract Notch signaling has been extensively implicated in cell-fate determination along the development of the immune system. However, a role for Notch signaling in fully differentiated immune cells has not been clearly defined. We have analyzed the expression of Notch protein family members during macrophage activation. Resting macrophages express Notch-1, -2, and -4, as well as the Notch ligands Jagged-1 and -2. After treatment with LPS and/or IFN-γ, we observed a p38 MAPK-dependent increase in ...
Tópico(s): Epigenetics and DNA Methylation
2006 - American Association of Immunologists | The Journal of Immunology
Paula Rubio‐Marqués, Antonio Leyva‐Pérez, Avelino Corma,
Nitroderivatives are transformed to cyclohexylanilines at room temperature in good yields and selectivity via a hydrogenation-amine coupling cascade reaction using Pd nanoparticles on carbon as a catalyst and a Brönsted acid.
Tópico(s): Catalytic Cross-Coupling Reactions
2013 - Royal Society of Chemistry | Chemical Communications
Javier Guzmán-Vargas, Enrique Ambrocio-Ortiz, Gloria Pérez‐Rubio, Marco Antonio Ponce-Gallegos, Rafael de Jesús Hernández-Zenteno, Mayra Mejía, Alejandra Ramírez‐Venegas, Ivette Buendia‐Roldán, Ramcés Falfán‐Valencia,
Background: Genetic association studies have identified single nucleotide polymorphisms (SNPs) associated with lasting lung diseases such as Chronic Obstructive Pulmonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF), as well as the simultaneous presentation, known as Combined Pulmonary Fibrosis and Emphysema (CPFE) Syndrome. It is unknown if these diseases share genetic variants previously described in an independent way. This study aims to identify common or differential variants between ...
Tópico(s): Pediatric health and respiratory diseases
2021 - Frontiers Media | Frontiers in Medicine
Gonzalo Mariscal, Jorge Morales, Silvia Pérez, Pedro Antonio Rubio-Belmar, Miquel Bovea-Marco, José Luis Bas, Paloma Bas, Teresa Bas,
Tópico(s): Spine and Intervertebral Disc Pathology
2022 - Springer Science+Business Media | European Spine Journal
Ezequiel López‐Rubio, José Muñoz Pérez, José Antonio Gómez‐Ruiz,
We propose a new self-organizing neural model that performs principal components analysis. It is also related to the adaptive subspace self-organizing map (ASSOM) network, but its training equations are simpler. Experimental results are reported, which show that the new model has better performance than the ASSOM network.
Tópico(s): Industrial Technology and Control Systems
2003 - Elsevier BV | Neural Networks
Gloria Pérez‐Rubio, Marco Antonio Ponce-Gallegos, Bruno André Domínguez-Mazzocco, Jaime Ponce-Gallegos, Román Alejandro García-Ramírez, Ramcés Falfán‐Valencia,
Influenza A virus (IAV) is the most common infectious agent in humans, and infects approximately 10–20% of the world’s population, resulting in 3–5 million hospitalizations per year. A scientific literature search was performed using the PubMed database and the Medical Subject Headings (MeSH) “Influenza A H1N1” and “Genetic susceptibility”. Due to the amount of information and evidence about genetic susceptibility generated from the studies carried out in the last influenza A H1N1 pandemic, studies ...
Tópico(s): Respiratory viral infections research
2021 - Multidisciplinary Digital Publishing Institute | Viruses
Mario Encinar, Aránzazu Martínez‐Gómez, Ramón G. Rubio, Ernesto Pérez, Antonio Bello, M. G. Prolongo,
Liquid crystalline polymers (LCPs) are complex systems that include features of both orientationally ordered mesophases and amorphous polymers. Frequently, the isotropic amorphous state cannot be studied due to the rapid mesophase formation. Here, a new main chain LCP, poly(triethyleneglycol methyl p,p'-bibenzoate), PTEMeB, has been synthesized. It shows a rather slow mesophase formation making possible to study independently both the amorphous and the liquid crystalline states. The structure and ...
Tópico(s): Polymer Nanocomposites and Properties
2012 - American Chemical Society | The Journal of Physical Chemistry B
Aquino Bruno Heberto, Plata Corona Juan Carlos, Castro Rubio José Antonio, Patricia Pulido‐Perez, Torres Rasgado Enrique, Julieta D. Morales-Portano, Gómez Álvarez Enrique Benito, Merino Rajme José Alfredo,
Respiratory illnesses is the most common manifestation of Coronavirus disease 2019 (COVID-19); however, myocardial injury has recently emerged as a frequent complication.An observational, longitudinal, prospective, and multicenter study of hospitalized Mexican patients was made. We assessed the prevalence of myocardial injury and its relationship with complications and mortality.254 COVID-19 patients were included. Their average age was 53.8 years old, 167 (65.7%) were male and 87 (34.3%) female. According ...
Tópico(s): COVID-19 and healthcare impacts
2020 - Elsevier BV | IJC Heart & Vasculature
Mercedes Jiménez‐Rosado, José Fernando Rubio‐Valle, Víctor Manuel Pérez Puyana, Antonio Guerrero, Alberto Romero,
The production of bioplastics from renewable and biodegradable sources could be a great potential option for the substitution of conventional plastics. In this way, raw materials and processing method have been investigated to improve their competitiveness in the actual market. However, the extra treatment that bioplastics must undergo to improve their properties are expensive, making them unfeasible. In this sense, a heat treatment in a conventional oven seems to be a potential low-cost option. ...
Tópico(s): Microplastics and Plastic Pollution
2020 - Elsevier BV | Sustainable Chemistry and Pharmacy
Mercedes Jiménez‐Rosado, José Fernando Rubio‐Valle, Víctor Manuel Pérez Puyana, Antonio Guerrero, Alberto Romero,
Abstract The elaboration of bioplastics from renewable polymers (e.g., proteins) is a field with great potential for industrial applications such as food packaging and agriculture. This study evaluates the development of bioplastic systems by injection molding using two different raw materials: soy protein isolate (SPI) and pea protein isolate (PPI). Both proteins are by‐products, which lowers the price of processed bioplastics. However, it is necessary to control their properties during the manufacture ...
Tópico(s): Nanocomposite Films for Food Packaging
2020 - Wiley | Journal of Applied Polymer Science
María Dolores Rubio Cintas, María Eugenia Parrón-Rubio, Francisca Pérez-García, António Bettencourt Ribeiro, Miguel José Oliveira,
Building construction and building operations have a massive direct and indirect effect on the environment. Cement-based materials will remain essential to supply the growth of our built environment. Without preventive measures, this necessary demand in cement production will imply a substantial increase in CO2 generation. Reductions in global CO2 emissions due to cement consumption may be achieved by improvements on two main areas: increased use of low CO2 supplementary cementitious materials and ...
Tópico(s): Innovative concrete reinforcement materials
2020 - Multidisciplinary Digital Publishing Institute | Sustainability
Tópico(s): Law, Ethics, and AI Impact
2015 - Centro Internacional de Estudios de Derecho Ambiental | Actualidad Jurídica Ambiental
Antonio M. Peinado, Victoria Sánchez, José L. Pérez-Córdoba, Antonio J. Rubio,
This work addresses the mitigation of channel errors by means of efficient minimum mean-square-error (MMSE) estimation. Although powerful model-based implementations have been recently proposed, the computational burden involved can make them impractical. We propose two new approaches that maintain a good level of performance with a low computational complexity. These approaches keep the simple structure and complexity of a raw MMSE estimation, although they enhance it with additional source a priori ...
Tópico(s): Speech Recognition and Synthesis
2005 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Wireless Communications
Antonio Bandera, José Manuel Pérez-Lorenzo, Antonio J. Rubio, F. Sandoval,
This paper proposes a new algorithm for extracting line segments from edge images. Basically, the method performs two consecutive stages. In the first stage, the algorithm follows a line segment random window randomized Hough transform (RWRHT) based approach. This approach provides a mechanism for finding more favorable line segments from a global point of view. In our case, the RWRHT based approach is used to actualise an accurate Hough parameter space. In the second stage, items of this parameter ...
Tópico(s): Remote Sensing and LiDAR Applications
2005 - Elsevier BV | Pattern Recognition Letters
Raquel Viciana-Abad, Rebeca Marfil, José Manuel Pérez-Lorenzo, Antonio J. Rubio, Adrián Romero‐Garcés, P. Reche López,
One of the main issues within the field of social robotics is to endow robots with the ability to direct attention to people with whom they are interacting. Different approaches follow bio-inspired mechanisms, merging audio and visual cues to localize a person using multiple sensors. However, most of these fusion mechanisms have been used in fixed systems, such as those used in video-conference rooms, and thus, they may incur difficulties when constrained to the sensors with which a robot can be ...
Tópico(s): Visual Attention and Saliency Detection
2014 - Multidisciplinary Digital Publishing Institute | Sensors
Gracia María Gallego‐Sendarrubias, José L. Arias‐Buría, Edurne Úbeda-D’Ocasar, Juan Pablo Hervás Pérez, Manuel Antonio Rubio-Palomino, César Fernández‐de‐las‐Peñas, Juan Antonio Valera‐Calero,
It has been suggested that Percutaneous Electrical Nerve Stimulation (PENS) can increase muscle strength. No previous study has investigated changes in performance in semiprofessional soccer players. This study compares the effects of adding two sessions of PENS to a training program versus the single training program over sport performance attributes (e.g., jump height and squat speed) in healthy soccer players. A cluster-randomized controlled trial was conducted on twenty-three semiprofessional ...
Tópico(s): Muscle activation and electromyography studies
2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Ezequiel López‐Rubio, José Muñoz Pérez, José Antonio Gómez‐Ruiz,
A new method for shape identification is proposed. It is not affected by similarity transformations (scalings, translations and rotations). The procedure is based on a robust index that gives the deformation of a self-organising feature map (SOFM) when it is trained with the object to identify.
Tópico(s): Image Retrieval and Classification Techniques
2001 - Elsevier BV | Pattern Recognition Letters
Regla Bustos, Gabriel Castrillo, Francisco Scaglia Linhares, María Isabel Puga, Vicente Rubio, Julián Pérez‐Pérez, Roberto Solano, Antonio Leyva, Javier Paz‐Ares,
Plants respond to different stresses by inducing or repressing transcription of partially overlapping sets of genes. In Arabidopsis, the PHR1 transcription factor (TF) has an important role in the control of phosphate (Pi) starvation stress responses. Using transcriptomic analysis of Pi starvation in phr1, and phr1 phr1-like (phl1) mutants and in wild type plants, we show that PHR1 in conjunction with PHL1 controls most transcriptional activation and repression responses to phosphate starvation, regardless ...
Tópico(s): Plant Stress Responses and Tolerance
2010 - Public Library of Science | PLoS Genetics
R. Mondéjar, Francisco Solano, R Mellado Rubio, Mercedes Delgado, Ángel Pérez Sempere, Antonio González‐Meneses, Teresa Vendrell, Guillermo Izquierdo, Amalia Martı́nez-Mir, Miguel Lucas,
Objective To study the molecular genetic and clinical features of cerebral cavernous malformations (CCM) in a cohort of Spanish patients. Methods We analyzed the CCM1, CCM2, and CCM3 genes by MLPA and direct sequencing of exons and intronic boundaries in 94 familial forms and 41 sporadic cases of CCM patients of Spanish extraction. When available, RNA studies were performed seeking for alternative or cryptic splicing. Results A total of 26 pathogenic mutations, 22 of which predict truncated proteins, ...
Tópico(s): Intracranial Aneurysms: Treatment and Complications
2014 - Public Library of Science | PLoS ONE
Kennosuke Karube, Anna Enjuanes, Iván Dlouhy, Pedro Jares, David Martin‐García, Ferran Nadeu, Gonzalo R. Ordóñez, Jordi Rovira, Guillem Clot, Cristina Royo, Alba Navarro, Blanca González‐Farré, Amineh Vaghefi, Giancarlo Castellano, Carlota Rubio-Pérez, David Tamborero, Javier Briones, Antonio Salar, Juan‐Manuel Sancho, Santiago Mercadal, Eva González‐Barca, Lourdes Escoda, Hiroaki Miyoshi, Koichi Ohshima, Kohta Miyawaki, Koji Kato, Koichi Akashi, Anna Mozos, Luís Colomo, Miguel Alcoceba, Alexandra Valera, Ana Carrió, Dolors Costa, Núria López-Bigas, Roland Schmitz, Louis M. Staudt, Itziar Salaverría, Armando López‐Guillermo, Elı́as Campo,
Genome studies of diffuse large B-cell lymphoma (DLBCL) have revealed a large number of somatic mutations and structural alterations. However, the clinical significance of these alterations is still not well defined. In this study, we have integrated the analysis of targeted next-generation sequencing of 106 genes and genomic copy number alterations (CNA) in 150 DLBCL. The clinically significant findings were validated in an independent cohort of 111 patients. Germinal center B-cell and activated ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2017 - Springer Nature | Leukemia
Andrés Sánchez-Pernaute, Miguel A. Rubio, Natalia Alonso Pérez, Clara Marcuello, Antonio Torres García, Elia Pérez-Aguirre,
Background One-loop duodenal switch leads to weight loss and improvement or resolution of co-morbidities similar to standard duodenal switch, and it is technically less demanding. Objectives To analyze the weight loss and metabolic improvement after conversion of sleeve gastrectomy to single-anastomosis duodenoileal bypass. Setting University Hospital, Madrid, Spain. Methods This was a retrospective cohort study. Patients submitted to sleeve gastrectomy with insufficient weight loss or programmed ...
Tópico(s): Gastroesophageal reflux and treatments
2020 - Elsevier BV | Surgery for Obesity and Related Diseases
Ana M. Wägner, Antoni Martínez‐Rubio, Jordi Ordóñez‐Llanos, Antonio Pérez‐Pérez,
Diabetes is associated with a high incidence and poor prognosis of cardiovascular disease, and with high short- and long-term mortality. Adequate treatment of cardiovascular disorders and aggressive management of coexisting risk factors have proved to be at least as effective in diabetic as in nondiabetic patients in randomized, controlled studies. Indeed, treating diabetic patients with cardiovascular disease results in a larger absolute risk reduction than in nondiabetic subjects. Nevertheless, ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2002 - Elsevier BV | European Journal of Internal Medicine
Antonio M. Gómez-Orellana, David Guijo-Rubio, Jorge Pérez-Aracíl, Pedro Antonio Gutiérrez, Sancho Salcedo‐Sanz, César Hervás‐Martínez,
In this paper we have tackled the problem of long-term air temperature prediction with eXplainable Artificial Intelligence (XAI) models. Specifically, we have evaluated the performance of an Artificial Neural Network (ANN) architecture with sigmoidal neurons in the hidden layer, trained by means of an evolutionary algorithm (Evolutionary ANNs, EANNs). This XAI model architecture (XAI-EANN) has been applied to the long-term air temperature prediction at different sub-regions of the South of the Iberian ...
Tópico(s): Hydrology and Watershed Management Studies
2023 - Elsevier BV | Atmospheric Research
Francisco J. Rubio-Serrano, Fernando Soto-Pérez, Antonio Trashorras,
The Hygroscopic cycle is a novel proprietary power cycle characterized by working with hygroscopic compounds which optimize the condensation of the turbine output steam in a steam absorber. This technology can be incorporated in any power plant that uses a Rankine cycle, obtaining higher electrical efficiency without limiting the cold sink temperature and without cooling water consumption. The novelty of this article is that Hygroscopic cycle is experimentally investigated in a test power plant ...
Tópico(s): Advanced Thermodynamics and Statistical Mechanics
2019 - Elsevier BV | Applied Thermal Engineering
Francisco J. Rubio-Serrano, Fernando Soto-Pérez, Antonio Trashorras,
Power output of power plant is substantially reduced when cooling is conducted at high ambient temperatures. The problem is also intensified at locations with water scarcity. Hygroscopic cycle is a novel technology that improves Rankine cycle and solve those problems in an effective way. Hygroscopic Cycle Technology works with hygroscopic compounds that increase the cooling temperature for each output pressure of the steam turbine and uses dry coolers for refrigeration. As a result, much better ...
Tópico(s): Solar Thermal and Photovoltaic Systems
2019 - Elsevier BV | Energy Conversion and Management
José A. Pérez‐Molina, Rafael Rubio, Antonio Rivero, Juan Pasquau, Ignacio Suárez-Lozano, Melcior Riera, Miriam Estébanez, Jesús Santos, José Sanz, Jesús Troya, Ana Mariño, Antonio Antela, Jordi Navarro, Herminia Esteban, Santiago Moreno,
Background Problems associated with lifelong antiretroviral therapy, such as need for strict adherence, drug-related toxic effects, difficulties with treatment schedules, and cost, mean that simplification strategies should be sought. We aimed to explore the efficacy and safety of dual treatment with atazanavir–ritonavir plus lamivudine as an option to switch to from standard combination antiretroviral therapy in patients with an HIV-1 infection who are virologically suppressed. Methods In this ...
Tópico(s): HIV/AIDS Research and Interventions
2015 - Elsevier BV | The Lancet Infectious Diseases