Paola Di Stefano, Laura Damiano, Sara Cabodi, Simona Aramu, Luca Tordella, Alice Praduroux, Roberto Piva, Federica Cavallo, Guido Forni, Lorenzo Silengo, Guido Tarone, Emilia Turco, Paola Defilippi,
... Search for more papers by this author Simona Aramu Simona Aramu Molecular Biotechnology Center, University of Torino, Turin, Italy ... Search for more papers by this author Simona Aramu Simona Aramu Molecular Biotechnology Center, University of Torino, Turin, Italy ...
Tópico(s): Cell Adhesion Molecules Research
2007 - Springer Nature | The EMBO Journal
Lucien F. Montaggioni, Bernard Salvat, Edwige Pons‐Branchu, Arnaud Dapoigny, Bertrand Martin‐Garin, Gilbert Poli, Jean-Marc Zanini, Robert Wan,
... dominated sequences from six excavations. Identified as Motu Aramu and Motu Vainono, these islets are located respectively ... leeward atoll sites, are protected from trade winds, Aramu, Vainono and Tekava are located on the windward ... over the last 5,000 years, at Motu Aramu, there is an apparent non-depositional episode, from ...
Tópico(s): Echinoderm biology and ecology
2023 - Elsevier BV | Natural Hazards Research
Gianfranco Fancello, Patrizia Serra, Valentina Aramu, Daniel Mark Vitiello,
Mediterranean container ports are constantly requested to face new market challenges after years of decline of their traffic in favour of a stronger leadership of Northern range ports, also favoured by the consolidation of the Arctic Route and the Belt and Road Initiative. To regain competitiveness, Mediterranean ports must undertake a path of operational, managerial and infrastructural strengthening. This study applies Data Envelopment Analysis (DEA) to 35 Mediterranean container ports in order ...
Tópico(s): Transport and Economic Policies
2021 - SAGE Publishing | Competition and Regulation in Network Industries
Silvia Grasso, Jennifer Chapelle, Vincenzo Salemme, Simona Aramu, Isabella Russo, Nicoletta Vitale, Ludovica Verdun di Cantogno, Katiuscia Dallaglio, Isabella Castellano, Augusto Amici, Giorgia Centonze, Nanaocha Sharma, Serena Lunardi, Sara Cabodi, Federica Cavallo, Alessia Lamolinara, Lorenzo Stramucci, Enrico Moiso, Paolo Provero, Adriana Albini, Anna Sapino, Johan Staaf, Pier Paolo Di Fiore, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Stefano Confalonieri, Manuela Iezzi, Paola Di Stefano, Emilia Turco, Paola Defilippi,
The docking protein p140Cap negatively regulates tumour cell features. Its relevance on breast cancer patient survival, as well as its ability to counteract relevant cancer signalling pathways, are not fully understood. Here we report that in patients with ERBB2-amplified breast cancer, a p140Cap-positive status associates with a significantly lower probability of developing a distant event, and a clear difference in survival. p140Cap dampens ERBB2-positive tumour cell progression, impairing tumour ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2017 - Nature Portfolio | Nature Communications
Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Masendu, Joseph Mberikunshe, Aramu Makuwaza,
This review outlines and discusses the new challenges in malaria control and prospects for its elimination in Mutare and Mutasa Districts, Zimbabwe. The burden of malaria has declined significantly over the past 5 years in most regions in Zimbabwe, including Mutare and Mutasa Districts. The nationwide malaria reduction has been primarily linked to scaled-up vector control interventions and early diagnosis and treatment with effective anti-malarial medicines. The successes recorded have prompted ...
Tópico(s): Viral Infections and Vectors
2016 - BioMed Central | Malaria Journal
Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Takudzwa Masendu, Sungai Mazando, Aramu Makuwaza,
Insecticide resistance in major malaria vectors poses severe challenges for stakeholders responsible for controlling the disease. During the 2013/14 season, malaria vector sentinel sites in Mutare and Mutasa Districts, Zimbabwe, experienced high presence of gravid malaria vector mosquitoes resting indoors in recently pyrethroid-sprayed structures. Subsequently, an evaluation of insecticide resistance in Anopheles funestus populations, the major malaria vector, was conducted to better inform the ...
Tópico(s): Insect Pest Control Strategies
2015 - BioMed Central | Malaria Journal
Smita Das, Tyler C. Henning, Limonty Simubali, Harry Hamapumbu, N Lukwa, Edmore Mamini, Aramu Makuwaza, Mbanga Muleba, Douglas E. Norris, Jennifer Stevenson,
Defining the anopheline mosquito vectors and their foraging behaviour in malaria endemic areas is crucial for disease control and surveillance. The standard protocol for molecular identification of host blood meals in mosquitoes is to morphologically identify fed mosquitoes and then perform polymerase chain reaction (PCR), precipitin tests, or ELISA assays. The purpose of this study was to determine the extent to which the feeding rate and human blood indices (HBIs) of malaria vectors were underestimated ...
Tópico(s): Invertebrate Immune Response Mechanisms
2015 - BioMed Central | Malaria Journal
Kwang Shik Choi, Riann Christian, Luisa Nardini, Oliver R. Wood, Eunice Agubuzo, Mbanga Muleba, Shungu Munyati, Aramu Makuwaza, Lizette L. Koekemoer, Basil D. Brooke, Richard H. Hunt, Maureen Coetzee,
Two mitochondrial DNA clades have been described in Anopheles funestus populations from southern Africa. Clade I is common across the continent while clade II is known only from Mozambique and Madagascar. The specific biological status of these clades is at present unknown. We investigated the possible role that each clade might play in the transmission of Plasmodium falciparum and the insecticide resistance status of An. funestus from Zimbabwe and Zambia.Mosquitoes were collected inside houses ...
Tópico(s): Insect Pest Control Strategies
2014 - BioMed Central | Parasites & Vectors
Daniele Repetto, Simona Aramu, Elisabetta Boeri Erba, Nanaocha Sharma, Silvia Grasso, Isabella Russo, Ole N. Jensen, Sara Cabodi, Emilia Turco, Paola Di Stefano, Paola Defilippi,
Protein phosphorylation tightly regulates specific binding of effector proteins that control many diverse biological functions of cells (e. g. signaling, migration and proliferation). p140Cap is an adaptor protein, specifically expressed in brain, testis and epithelial cells, that undergoes phosphorylation and tunes its interactions with other regulatory molecules via post-translation modification. In this work, using mass spectrometry, we found that p140Cap is in vivo phosphorylated on tyrosine ( ...
Tópico(s): Protein Degradation and Inhibitors
2013 - Public Library of Science | PLoS ONE
Sara Cabodi, Paola Di Stefano, Maria del Pilar Camacho Leal, Agata A. Tinnirello, Brigitte Bisarò, Virginia Morello, Laura Damiano, Simona Aramu, Daniele Repetto, Giusy Tornillo, Paola Defilippi,
Integrin signaling has a critical function in organizing cells in tissues during both embryonic development and tissue repair. Following their binding to the extracellular ligands, the intracellular signaling pathways triggered by integrins are directed to two major functions: organization of the actin cytoskeleton and regulation of cell behaviour including survival, differentiation and growth. Basic research conducted in the past twelve years has lead to remarkable breakthroughs in this field. ...
Tópico(s): Signaling Pathways in Disease
2010 - Springer Nature | Advances in experimental medicine and biology
Erika Cottone, Ezio Campantico, Alda Guastalla, STEFANIA ARAMU, A.M. Polzonetti‐Magni, Mariafosca Franzoni,
Following the discovery of two CB1 genes in the fish Fugu rubripes, investigations on the phylogeny of endocannabinoids have indicated that this system is highly conserved. Our study demonstrated that CB1 receptors are expressed in the CNS and gonads of two teleosts, Carassius auratus and Pelvicachromis pulcher, and they show a high percentage of sequence identity with Fugu rubripes CB(1A) and Danio rerio CB1. By means of immunohistochemistry for CB1, sGnRH, and TH, we found a codistribution of ...
Tópico(s): Diet, Metabolism, and Disease
2005 - Wiley | Annals of the New York Academy of Sciences
The effect of γ-ray collimation geometry in measuring Mössbauer absorption spectra is studied quantitatively. It is found that the spectra undergo an expansion around zero velocity and the more the collimator allows high flows of γ-rays, the more important is the expansion. Equations are proposed to correct for this effect.
Tópico(s): Advanced X-ray Imaging Techniques
1970 - Elsevier BV | Nuclear Instruments and Methods
F. Aramu, P. Brovetto, A. Rucci,
Experimental results giving some evidence of activation energy varying with temperature in NaCl thermoluminescence are reported.
Tópico(s): Molecular Junctions and Nanostructures
1966 - Elsevier BV | Physics Letters
The main features of a self-modulating derivative densitometer as well as some typical results of the new method are reported. By comparing both derivative and nonderivative analysis of a spectrum conventionally recorded on a spectrographic plate, one can see that its detectability is increased by a factor much greater than 1. These experimental results are consistent with the gain to be expected by means of optical derivative spectroscopy.
Tópico(s): Mechanical and Optical Resonators
1966 - American Institute of Physics | Review of Scientific Instruments
Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Masendu, Aramu Makuwaza,
Biting behaviour of Anopheles funestus in Mutare and Mutasa districts, Zimbabwe, is little understood. An investigation was conducted to primarily compare indoor and outdoor biting behaviour of the mosquito, as well as blood meal sources and sporozoite rates.Monthly adult anopheline sampling was conducted from October 2013 to September 2014 using Centers for Disease Control light-traps, pyrethrum spray catch and artificial pit shelter methods. Mosquitoes sampled by light-traps were divided into ...
Tópico(s): Invertebrate Immune Response Mechanisms
2016 - Medknow | Journal of Vector Borne Diseases
Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Masendu, Aramu Makuwaza,
Regular entomological monitoring is important to determine changes in mosquito species composition and relative densities of malaria vectors in relation to vector control interventions. A study to gain insights into malaria vector species composition and relative abundance was undertaken in Mutare and Mutasa districts, Zimbabwe. Two methods; indoor resting catches and larval sampling were used to collect indoor resting adults and larvae from May 2013 to April 2014. Mosquitoes collected as adults ...
Tópico(s): Insect Pest Control Strategies
2015 - PAGEPress (Italy) | Journal of Entomological and Acarological Research
F. Aramu, T. Bressani, P. Manca,
Tópico(s): Magnetic Properties and Synthesis of Ferrites
1967 - Springer Nature | Il Nuovo Cimento B
Sungano Mharakurwa, Zvifadzo Matsena Zingoni, Nobert Mudare, Charmaine Matimba, Tanatswa Xuxa Gara, Aramu Makuwaza, Gladys Maponga, Shungu Munyati, Lovemore Gwanzura, Susan Mutambu, Peter Mason, Tamaki Kobayashi, Nicholas Midzi, William J. Moss, Matthew M. Ippolito,
Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact ...
Tópico(s): Travel-related health issues
2020 - Oxford University Press | The Journal of Infectious Diseases
Tópico(s): Advanced Chemical Physics Studies
1964 - Italian Physical Society | Il Nuovo Cimento
N Lukwa, Shadreck Sande, Aramu Makuwaza, Tonderai Chiwade, Martin Netsa, Kwame Asamoa, Gonzalo M. Vazquez‐Prokopec, Richard Reithinger, Jacob Williams,
The scale-up of malaria interventions in sub-Saharan Africa has been accompanied by a dramatic increase in insecticide resistance in Anopheles spp. In Zimbabwe resistance to pyrethroid insecticides was reported in Gokwe District in 2008. This study reports results of the first nation-wide assessment of insecticide susceptibility in wild populations of Anopheles gambiae sensu lato (s.l.) in Zimbabwe, and provides a comprehensive review of the insecticide resistance status of An. gambiae s.l. in southern ...
Tópico(s): Insect Resistance and Genetics
2014 - BioMed Central | Malaria Journal
Abstract The thermoluminescent emissions of some aromatic hydrocarbon crystals have been investigated as excited at liquid N 2 temperature by UV light. Diffuse scattering measurements have been also performed for determining the absorption and excitation spectra. The results are interpreted on the basis of a kinetic model, which accounts for the photoluminescent properties too. Evidence is obtained as to the effect of the molecular structure on the thermoluminescent emission efficiency.
Tópico(s): Phase Equilibria and Thermodynamics
1975 - Elsevier BV | Journal of Luminescence
Tópico(s): Photochemistry and Electron Transfer Studies
1976 - Elsevier BV | Journal of Luminescence
F. Aramu, V. Maxia, G. Spano, C. Cortese,
The problem of the thermoluminescence building-up, that is of the carrier production and storage during the phosphor excitation, is faced by the same kinetic model which allows for the thermoluminescent emission, that is, for the carrier recombinations. Equations are given suited to perform quantitative comparisons with the experiment. Measurements on ZnS and AgCl crystals show the reliability of the model and yield values for the ratio of retrapping to recombination probabilities in agreement with ...
Tópico(s): Ammonia Synthesis and Nitrogen Reduction
1975 - Elsevier BV | Journal of Luminescence
F. Aramu, V. Maxia, C. Muntoni,
Two instruments are described suited for recording thermoluminescent glow spectra respectively below and above room temperature. Their most remarkable property is the fact that the samples are kept under vacuum. Thermal insulation, thus, is good enough to allow samples to be placed only 15 mm from the light detector, even if they are heated up to 500 °C or cooled down to liquid N2 temp. Consequently, the light collection efficiency turns out to be very high. These instruments are equipped with both ...
Tópico(s): Advanced Chemical Sensor Technologies
1974 - American Institute of Physics | Review of Scientific Instruments
The thermoluminescent emissions of AgCl and AgBr crystals have been investigated as excited at liquid N2 temperature with UV light. The spectra of both halides were found to exhibit a single glow peak, with maxima at 140 and 124 ° K respectively. Analysis of the data yields an activation energy of 0.13 eV for AgCl and 0.096 for AgBr. The trapping centres are identified with Frenkel defects and evidence is obtained in favour of the carrier trap situation presupposed by the Mitchell and Mott model for ...
Tópico(s): Advanced Chemical Physics Studies
1974 - Elsevier BV | Journal of Luminescence
F. Aramu, V. Maxia, Maria Paola Serra, G. Spano,
The thermoluminescence glow spectra of ortho, meta and para-hydroxy and aminobenzoic acids have been investigated as obtained through UV excitation at low temperature. The trap depths are found to range from 0.13-0.39 eV for the various acids, while the trap density turns out to be highest in the ortho-forms. This feature is ascribed to the poorer stability of the dimers in the ortho-acids, which produces a larger concentration of lattice defects. This conclusion is substantiated by means of different ...
Tópico(s): Molecular Junctions and Nanostructures
1972 - Elsevier BV | Journal of Luminescence
Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Masendu, Aramu Makuwaza,
A study was conducted to investigate the current resting behavior of malaria vectors in Mutare and Mutasa districts, Zimbabwe. Mosquitoes were captured using pyrethrum spray collection, prokopac aspirator, pit shelter, and exit trap methods. Mosquitoes were sorted and identified using morphological key and polymerase chain reaction (PCR) techniques. The Anopheles funestus group constituted 97%, whereas Anopheles gambiae complex mosquitoes were few (3%). Endophilic collections in both species were ...
Tópico(s): Insect Pest Control Strategies
2016 - Oxford University Press | Journal of Medical Entomology
The thermoluminescent emission of phenanthrene crystals, UV excited at liquid N2 temperature, is investigated on the basis of a previously proposed kinetic model. It is found to fit quantitatively the glow peak shape and some evidence is obtained that radiative recombinations take place through a two-step process.
Tópico(s): Atmospheric chemistry and aerosols
1975 - Elsevier BV | Journal of Luminescence
U.V. excited thermoluminescence of ten textile fibres is investigated above liquid N2 temperature. The results seem to indicate that the glow peak peculiarities are mainly due to structural defects or chemical impurities. The kinetic order of the process is always found to be 1.
Tópico(s): Photonic Crystals and Applications
1971 - Elsevier BV | Journal of Luminescence
Nobert Mudare, Zvifadzo Matsena Zingoni, Aramu Makuwaza, Edmore Mamini, Shungu Munyati, Lovemore Gwanzura, Nicholas Midzi, Susan Mutambu, Peter Mason, Tamaki Kobayashi, Sungano Mharakurwa,
Abstract Background Microscopy and rapid diagnostic tests (RDTs) are the main techniques used to diagnose malaria. While microscopy is considered the gold standard, RDTs have established popularity as they allow for rapid diagnosis with minimal technical skills. This study aimed to compare the diagnostic performance of two Plasmodium falciparum histidine-rich protein 2 (PfHRP2)-based RDTs (Paracheck Pf® Test (Paracheck) and Malaria Pf™ ICT (ICT)) to polymerase chain reaction (PCR) in a community survey. ...
Tópico(s): HIV Research and Treatment
2021 - BioMed Central | Malaria Journal