... who have applied for admission (Jones, 1990; Mellott, Arden, & Cho, 1997). The reference letter can thus be viewed ...
Tópico(s): Educational Leadership and Administration
1999 - SAGE Publishing | Professional School Counseling
Ramona N. Mellott, Irene A. Arden, Meg E. Cho,
This article's major objective is to effectively prepare the graduate student in psychology for the internship application process by providing critical and relevant information. Preparation begins early on in one's graduate career and usually involves the following steps: (a) establishing mentoring relationships, (b) preparing an application portfolio, (c) collecting information, (d) applying, (e) interviewing, ( f ) ranking the selected agencies, and (g) responding on selection day. Information is also ...
Tópico(s): Medical Education and Admissions
1997 - American Psychological Association | Professional Psychology Research and Practice
Yue Yang, Tomoko Yamada, Kelly Hill, Martin Hemberg, Naveen C. Reddy, Ha Y. Cho, Arden N. Guthrie, Anna Oldenborg, Shane A. Heiney, Shogo Ohmae, Javier F. Medina, Timothy E. Holy, Azad Bonni,
Activity-dependent transcription influences neuronal connectivity, but the roles and mechanisms of inactivation of activity-dependent genes have remained poorly understood. Genome-wide analyses in the mouse cerebellum revealed that the nucleosome remodeling and deacetylase (NuRD) complex deposits the histone variant H2A.z at promoters of activity-dependent genes, thereby triggering their inactivation. Purification of translating messenger RNAs from synchronously developing granule neurons (Sync-TRAP) ...
Tópico(s): RNA Research and Splicing
2016 - American Association for the Advancement of Science | Science
Ryan W. Walker, Gillian M. Belbin, Elena P. Sorokin, Tielman Van Vleck, Genevieve L. Wojcik, Arden Moscati, Christopher R. Gignoux, Judy H. Cho, Noura S. Abul‐Husn, Girish N. Nadkarni, Eimear E. Kenny, Ruth J. F. Loos,
•Natural language processing increased NAFLD detection over ICD codes by 2.5 times. •rs738409 “GG” carriers were diagnosed with NAFLD 3 years earlier than non-carriers. •PNPLA3 rs738409 effects were most pronounced in Hispanics. •PheWAS showed rs738409 was associated with other NAFLD-related liver diseases. •rs738409 was associated with earlier diagnosis for PheWAS-identified diseases. Background & Aims The Ile138Met variant (rs738409) in the PNPLA3 gene has the largest effect on non-alcoholic fatty liver ...
Tópico(s): Diabetes and associated disorders
2020 - Elsevier BV | Journal of Hepatology
Tópico(s): Human Resource Development and Performance Evaluation
1997 - American Psychological Association | Professional Psychology Research and Practice
Tópico(s): Academic and Historical Perspectives in Psychology
1997 - American Psychological Association | Professional Psychology Research and Practice
Scott Cho, Samuel Edmondson, Arden D. Miller, MacLean Sellars, Shawn T. Alexander, Selin Somersan, Jennifer A. Punt,
Abstract Autoreactive thymocytes can be eliminated by clonal deletion during their development in the thymus. The precise developmental stage(s) at which clonal deletion occurs in a normal thymus has been difficult to assess, in large part because of the absence of a specific marker for TCR-mediated apoptosis. In this report, we reveal that Nur77 expression can be used as a specific marker of clonal deletion in an unmanipulated thymus and directly identify TCRintCD4+CD8+ and semimature CD4+CD8− ...
Tópico(s): Whipple's Disease and Interleukins
2003 - American Association of Immunologists | The Journal of Immunology
Noura S. Abul‐Husn, Emily R. Soper, Giovanna T. Braganza, Jessica Rodriguez, Natasha Zeid, Sinéad Cullina, Dean Bobo, Arden Moscati, Amanda Merkelson, Ruth J. F. Loos, Judy H. Cho, Gillian M. Belbin, Sabrina A. Suckiel, Eimear E. Kenny,
Population-based genomic screening has the predicted ability to reduce morbidity and mortality associated with medically actionable conditions. However, much research is needed to develop standards for genomic screening and to understand the perspectives of people offered this new testing modality. This is particularly true for non-European ancestry populations who are vastly underrepresented in genomic medicine research. Therefore, we implemented a pilot genomic screening program in the BioMe Biobank ...
Tópico(s): Genomic variations and chromosomal abnormalities
2021 - BioMed Central | Genome Medicine
Noura S. Abul‐Husn, Emily R. Soper, Jacqueline A. Odgis, Sinéad Cullina, Dean Bobo, Arden Moscati, Jessica Rodriguez, Ruth J. F. Loos, Judy H. Cho, Gillian M. Belbin, Sabrina A. Suckiel, Eimear E. Kenny,
Pathogenic variants in BRCA1 and BRCA2 (BRCA1/2) lead to increased risk of breast, ovarian, and other cancers, but most variant-positive individuals in the general population are unaware of their risk, and little is known about prevalence in non-European populations. We investigated BRCA1/2 prevalence and impact in the electronic health record (EHR)-linked BioMe Biobank in New York City.Exome sequence data from 30,223 adult BioMe participants were evaluated for pathogenic variants in BRCA1/2. Prevalence ...
Tópico(s): Genomics and Rare Diseases
2019 - BioMed Central | Genome Medicine
Michael Sy, Arden Panotes, Daniella Cho, Roi Charles Pineda, Priya Martin,
Service user involvement in interprofessional education and collaborative practice remains limited despite the increasing push for this by governments and grant funding bodies. This rapid review investigated service user involvement in interprofessional education, practice, and research to determine factors that enable or hinder such involvement. Following the Cochrane and the World Health Organization’s rapid review guidelines, a targeted search was undertaken in four databases. Subsequent to the ...
Tópico(s): Chronic Disease Management Strategies
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Ramona N. Mellott, Irene A. Arden, Meg E. Cho,
Tópico(s): Global Health Workforce Issues
1997 - American Psychological Association | Professional Psychology Research and Practice
Ernie Chen, Ling-Shiang Chuang, Mamta Giri, Nicole Villaverde, Nai-Yun Hsu, Ksenija Sabic, Sari Joshowitz, Kyle Gettler, Shikha Nayar, Zhi Chai, Isaac L. Alter, Colleen Chasteau, Ujunwa Korie, Siarhei Dzedzik, Tin Htwe Thin, Aayushee Jain, Arden Moscati, Gerold Bongers, Richard H. Duerr, Mark S. Silverberg, Steven R. Brant, John D. Rioux, Inga Peter, L. Philip Schumm, Talin Haritunians, Dermot McGovern, Yuval Itan, Judy H. Cho,
Background & Aims Recent literature has implicated a key role for mast cells in murine models of colonic inflammation, but their role in human ulcerative colitis (UC) is not well established. A major advance has been the identification of mrgprb2 (human orthologue, MRGPX2) as mediating IgE-independent mast cell activation. We sought to define mechanisms of mast cell activation and MRGPRX2 in human UC. Methods Colon tissues were collected from patients with UC for bulk RNA sequencing and lamina propria ...
Tópico(s): Asthma and respiratory diseases
2021 - Elsevier BV | Gastroenterology
Gillian M. Belbin, Sinéad Cullina, Stéphane Wenric, Emily R. Soper, Benjamin S. Glicksberg, Denis Torre, Arden Moscati, Genevieve L. Wojcik, Ruhollah Shemirani, Noam D. Beckmann, Ariella Cohain, Elena P. Sorokin, Danny S. Park, José Luis Ambite, Ian O. Ellis, Adam Auton, Erwin P. Böttinger, Judy H. Cho, Ruth J. F. Loos, Noura S. Abul‐Husn, Noah Zaitlen, Christopher R. Gignoux, Eimear E. Kenny,
Understanding population health disparities is an essential component of equitable precision health efforts. Epidemiology research often relies on definitions of race and ethnicity, but these population labels may not adequately capture disease burdens and environmental factors impacting specific sub-populations. Here, we propose a framework for repurposing data from electronic health records (EHRs) in concert with genomic data to explore the demographic ties that can impact disease burdens. Using ...
Tópico(s): Epigenetics and DNA Methylation
2021 - Cell Press | Cell
Chai Young Jung, Jong-Ye Choi, Seong Jik Jeong, Kyunghee Cho, Yong Duk Koo, Jin Hee Bae, Sukil Kim,
Arden Syntax is a Health Level Seven International (HL7) standard language that is used for representing medical knowledge as logic statements. Arden Syntax Markup Language (ArdenML) is a new representation of Arden Syntax based on XML. Compilers are required to execute medical logic modules (MLMs) in the hospital environment. However, ArdenML may also replace the compiler. The purpose of this study is to demonstrate that MLMs, encoded in ArdenML, can be transformed into a commercial rule engine format ...
Tópico(s): Biomedical Text Mining and Ontologies
2016 - Elsevier BV | Artificial Intelligence in Medicine
Margaret A. Taub, Matthew P. Conomos, Rebecca Keener, Kruthika Iyer, Joshua S. Weinstock, Lisa R. Yanek, John Lane, Tyne W. Miller‐Fleming, Jennifer A. Brody, Laura M. Raffield, Caitlin McHugh, Deepti Jain, Stephanie M. Gogarten, Cecelia Laurie, Ali R. Keramati, Marios Arvanitis, Albert V. Smith, Ben Heavner, Lucas Barwick, Lewis C. Becker, Joshua C. Bis, John Blangero, Eugene R. Bleecker, Esteban G. Burchard, Juan C. Celedón, Yen Chang, Brian Custer, Dawood Darbar, Lisa de las Fuentes, Dawn L. DeMeo, Barry I. Freedman, Melanie E. Garrett, Mark T. Gladwin, Susan R. Heckbert, Bertha Hidalgo, Marguerite R. Irvin, Talat Islam, W. Craig Johnson, Stefan Kääb, Lenore Launer, Jiwon Lee, Simin Liu, Arden Moscati, Kari E. North, Patricia A. Peyser, Nicholas Rafaels, Christine E. Seidman, Daniel E. Weeks, Fayuan Wen, Marsha M. Wheeler, L. Keoki Williams, Ivana V. Yang, Wei Zhao, Stella Aslibekyan, Paul L. Auer, Donald W. Bowden, Brian E. Cade, Zhanghua Chen, Michael H. Cho, L. Adrienne Cupples, Joanne E. Curran, Michelle Daya, Ranjan Deka, Celeste Eng, Tasha E. Fingerlin, Xiuqing Guo, Lifang Hou, Shih‐Jen Hwang, Jill M. Johnsen, Eimear E. Kenny, Albert M. Levin, Chunyu Liu, Ryan L. Minster, Take Naseri, Mehdi Nouraie, Muagututi‘a Sefuiva Reupena, Éster Cerdeira Sabino, Jennifer A. Smith, Nicholas L. Smith, Jessica Lasky‐Su, James G. Taylor, Marilyn J. Telen, Hemant K. Tiwari, Russell P. Tracy, Marquitta J. White, Yingze Zhang, Kerri L. Wiggins, Scott T. Weiss, Ramachandran S. Vasan, Kent D. Taylor, Moritz F. Sinner, Edwin K. Silverman, M. Benjamin Shoemaker, Wayne H.-H. Sheu, Frank C. Sciurba, David A. Schwartz, Jerome I. Rotter, Daniel Roden, Susan Redline, Benjamin A. Raby, Bruce M. Psaty, Juan M. Peralta, Nicholette D. Palmer, Sergeï Nekhai, Courtney G. Montgomery, Braxton D. Mitchell, Deborah A. Meyers, Stephen T. McGarvey, Angel C. Y. Mak, Ruth J. F. Loos, Rajesh Kumar, Charles Kooperberg, Barbara A. Konkle, Shannon Kelly, Sharon L. R. Kardia, Robert C. Kaplan, Jiang He, Hongsheng Gui, Frank D. Gilliland, Bruce D. Gelb, Myriam Fornage, Patrick T. Ellinor, Mariza de Andrade, Adolfo Correa, Yii‐Der Ida Chen, Eric Boerwinkle, Kathleen C. Barnes, Allison E. Ashley‐Koch, Donna K. Arnett, Christine M. Albert, Cathy C. Laurie, Gonçalo R. Abecasis, Deborah A. Nickerson, James G. Wilson, Stephen S. Rich, Daniel Levy, Ingo Ruczinski, Abraham Aviv, Thomas W. Blackwell, Timothy A. Thornton, Jeff O’Connell, Nancy J. Cox, James A. Perry, Mary Armanios, Alexis Battle, Nathan Pankratz, Alexander P. Reiner, Rasika A. Mathias,
Genetic studies on telomere length are important for understanding age-related diseases. Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based association study for TL across ancestrally diverse individuals (European, African, Asian, and Hispanic/Latino) from the NHLBI Trans-Omics for Precision Medicine (TOPMed) program. We used whole-genome sequencing (WGS) of whole blood for variant genotype calling and the bioinformatic estimation ...
Tópico(s): Single-cell and spatial transcriptomics
2022 - Elsevier BV | Cell Genomics
Stefan Schölzel, Wolfgang Zimmermann, Georg Schwarzkopf, Fritz Grunert, Brigitta Rogaczewski, John A. Thompson,
... PubMed Scopus (52) Google Scholar A newly developed CHO transfectant was included that expresses CEACAM7 and was recently developed in our laboratory with the use of CEACAM7 cDNA that was described elsewhere.21Thompson J Zimmermann W Nollau P Neumaier M Weber-Arden J Schrewe H Craig I Willcocks T CGM2, ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2000 - Elsevier BV | American Journal Of Pathology
Sunhong Kim, Kwangho Jee, Dohoon Kim, Hyongjong Koh, Jongkyeong Chung,
... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... 3 activation (50Srivastava R.K. Srivastava A.R. Cho-Chung Y.S. Longo D.L. Oncogene. 1999; ...
Tópico(s): Cancer Mechanisms and Therapy
2001 - Elsevier BV | Journal of Biological Chemistry
Jake A. Kushner, Laura J. Simpson, Lynn M. Wartschow, Shaodong Guo, Matthew M. Rankin, Ramon Parsons, Morris F. White,
... W.H. Wright C.V. White M.F. Arden K.C. Accili D. J. Clin. Investig. 2002; ... W.H. Wright C.V. White M.F. Arden K.C. Accili D. J. Clin. Investig. 2002; ... W.H. Wright C.V. White M.F. Arden K.C. Accili D. J. Clin. Investig. 2002; ... W.H. Wright C.V. White M.F. Arden K.C. Accili D. J. Clin. Investig. 2002; ...
Tópico(s): Metabolism, Diabetes, and Cancer
2005 - Elsevier BV | Journal of Biological Chemistry
Andrew Sunters, Silvia Fernández de Mattos, Marie Ståhl, Jan J. Brosens, Georgia Zoumpoulidou, Catherine Saunders, Paul J. Coffer, René H. Medema, R. Charles Coombes, Eric W.‐F. Lam,
... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... H. Meisenhelder J. Hunter T. Cavenee W.K. Arden K.C. Proc. Natl. Acad. Sci. U. S. ... cancer (26.Page C. Huang M. Jin X. Cho K. Lilja J. Reynolds R.K. Lin J. ...
Tópico(s): Cancer Mechanisms and Therapy
2003 - Elsevier BV | Journal of Biological Chemistry
Brittney Jung‐Hynes, Minakshi Nihal, Weixiong Zhong, Nihal Ahmad,
... Viars C.S. Czekay S. Cavenee W.K. Arden K.C. Genomics.. 1998; 47: 187-199Google Scholar), ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell.. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell.. ...
Tópico(s): Autophagy in Disease and Therapy
2008 - Elsevier BV | Journal of Biological Chemistry
Yvonne Ng, Georg Ramm, James G. Burchfield, Adelle C.F. Coster, Jacqueline Stöckli, David E. James,
... H. Meisenhelder J. Hunter T. Cavenee W.K. Arden K.C. Proc. Natl. Acad. Sci. U.S. ... H. Meisenhelder J. Hunter T. Cavenee W.K. Arden K.C. Proc. Natl. Acad. Sci. U.S. ... muscle, adipose tissue, and liver (5Whiteman E.L. Cho H. Birnbaum M.J. Trends Endocrinol. Metab. 2002; ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2009 - Elsevier BV | Journal of Biological Chemistry
Makoto Hiromura, Futoshi Suizu, Masumi Narita, Keiichi Kinowaki, Masayuki Noguchi,
... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ...
Tópico(s): Macrophage Migration Inhibitory Factor
2006 - Elsevier BV | Journal of Biological Chemistry
Jean Picquet, Oscar J. Abilez, J. Penard, Y. Jousset, Marie Christine Rousselet, B Enon,
... Berguer R. Kline R.A. Jacobs J.R. Arden R.L. Carotid resection and replacement with autogenous ... PubMed Scopus (43) Google Scholar, 20Jacobs J.R. Arden R.L. Marks S.C. Kline R. Berguer ...
Tópico(s): Abdominal vascular conditions and treatments
2005 - Elsevier BV | Journal of Vascular Surgery
Robert Somerville, Jean‐Michel Longpré, Katherine A. Jungers, J. Michael Engle, Monique Ross, Stephen P. Evanko, Thomas N. Wight, Richard Leduc, Suneel Apte,
... Kelner G.S. Turbeville L.A. Boyer A. Arden K.C. Maki R.A. Genomics. 2000; 67: ... Kelner G.S. Turbeville L.A. Boyer A. Arden K.C. Maki R.A. Genomics. 2000; 67: ... PerkinElmer Life Sciences), dried, and exposed for fluorography. CHO.RPE 40 cells (22Spence M.J. Sucic J. ...
Tópico(s): Complement system in diseases
2003 - Elsevier BV | Journal of Biological Chemistry
Laurent Muller, Angus Cameron, Yolanda M. Fortenberry, Ekaterina V. Apletalina, Iris Lindberg,
... life in the hour range (31Guest P.C. Arden S.D. Bennett D.L. Clark A. Rutherford ... to pro-PC2 and PC2 (31Guest P.C. Arden S.D. Bennett D.L. Clark A. Rutherford ... Pro-PC2 was purified from the medium of CHO cells expressing high levels of pro-PC2 and ...
Tópico(s): Biotin and Related Studies
2000 - Elsevier BV | Journal of Biological Chemistry
Stuart R. Arden, Jeroo D. Sinor, William K. Potthoff, Elias Aizenman,
... medium, Life Technologies, Inc. Chinese hamster ovary cells (CHO-K1; ATTC CCL61) were grown in Ham's ... 10% fetal bovine serum, and 1 mm glutamine (CHO media) in 50- or 200-ml flasks at ... Technologies, Inc.) in 1 ml of serum-free CHO media per well. Of the total DNA 0. ... with the transfection solution, cells were refed with CHO medium containing 300 μm ketamine or 1 mm5, ... DTT and DTNB on recombinant receptors expressed in CHO cells (33Boeckman F.A. Aizenman E. Neurosci. Lett. ... or NR1(C744S) subunits were transiently transfected into CHO cells along with either NR2A or NR2B to ...
Tópico(s): Peroxisome Proliferator-Activated Receptors
1998 - Elsevier BV | Journal of Biological Chemistry
Takashi Katome, Toshiyuki Obata, Rie Matsushima, Norihisa Masuyama, Lewis C. Cantley, Yukiko Gotoh, Kazuhiro Kishi, Hiroshi Shiota, Yousuke Ebina,
... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Cell. ... Culture—COS-7 cells and Chinese hamster ovary (CHO) cells stably expressing Myc-tagged rat glucose transporter ... TCID50) was determined as pfu/ml, and either CHO cells or 3T3-L1 adipocytes were infected at ... MOI; pfu/cell), as indicated. Adenoviral Gene Transduction—CHO-GLUT4myc cells or 3T3-L1 adipocytes (the 8th ... Dominant Negative Akt Inhibited Insulin Actions in Both CHO Cells and 3T3-L1 Adipocytes—We generated recombinant ... adenovirus markedly enhanced Akt kinase activity in both CHO cells and 3T3-L1 adipocytes. In parallel, the ...
Tópico(s): Pancreatic function and diabetes
2003 - Elsevier BV | Journal of Biological Chemistry
Xiang‐An Li, William B. Titlow, Brian A. Jackson, Nathalia Giltiay, Mariana Nikolova‐Karakashian, Annette Uittenbogaard, Eric J. Smart,
... Inc., Rockville, MD) (19.Jorgensen M. Wagner P. Arden W. Jackson B. J. Neurosci. Res. 2000; 59: ... mechanism responsible for this stimulation. We used ldl7A CHO cells to examine the potential role of SR- ... Fig. 1 is an immunoblot demonstrating that the CHO cell lines express SR-BI, eNOS, or both ... causes an increase in intracellular calcium, we loaded CHO cells expressing SR-BI and eNOS with fura- ... to SR-BI promoted Akt activation, we treated CHO cells expressing both SR-BI and eNOS with ... confirm this finding, we measured eNOS activity in CHO cells expressing both SR-BI and eNOS in ...
Tópico(s): Sphingolipid Metabolism and Signaling
2002 - Elsevier BV | Journal of Biological Chemistry
Nilou Arden, Brian S. Majors, Shin‐hyung Ahn, George A. Oyler, Michael J. Betenbaugh,
... E3 ubiquitin ligase for p53. Both 293 and CHO cells expressing MDM2 were examined under both batch ... control cells with the largest enhancements observed in CHO cells. When CHO cells were passaged without medium exchange, cells expressing ... to spent media initially, both 293–MDM2 and CHO–MDM2 cells continued to grow for 2 days ... DNA analysis using flow cytometry confirmed that while CHO controls were found to be undergoing DNA fragmentation, CHO–MDM2 cells exhibit DNA degradation at a much ...
Tópico(s): Cancer Research and Treatments
2006 - Wiley | Biotechnology and Bioengineering
Dandan Wang, Xiaoxiao Yang, Yuanli Chen, Ke Gong, Maoyun Yu, Yongyao Gao, Ximei Wu, Huaqing Hu, Chenzhong Liao, Jihong Han, Yajun Duan,
... Juo P. Hu L.S. Anderson M.J. Arden K.C. Blenis J. Greenberg M.E. Akt ... of determinants for circulating PCSK9, LDL and total CHO levels. To determine it, we collected serum samples form 24 volunteers and determined levels of CHO, LDL, PCSK9, and ascorbic acid. Consistent with the previous study, serum CHO and LDL levels were positively correlated to PCSK9 ... ascorbic acid levels were negatively correlated to serum CHO and LDL levels (Fig. 6, L and M), ...
Tópico(s): Vitamin C and Antioxidants Research
2020 - Elsevier BV | Journal of Biological Chemistry