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Artigo Acesso aberto Revisado por pares

Susana Dias, Maria Eduarda Potes, Artur Armando de Moura Marinho, Manuel Malfeito‐Ferreira, V. Loureiro,

The evolution of the yeast flora was studied for an artisanal semi-hard ewes' cheese made from raw milk. Mean log10 yeast counts per gram of cheese body ranged from 2.7 to 6.4, with the higher counts observed after a ripening period of 30 days. The yeast population decreased thereafter and, at the end of curing process, reached values similar to those of the beginning. A total of 344 yeasts strains were randomly isolated from the curd and cheese body during the 60 days long ripening period. Esterase ...

Tópico(s): Yeasts and Rust Fungi Studies

2000 - Elsevier BV | International Journal of Food Microbiology

Artigo Acesso aberto Revisado por pares

Artur Evangelista, Armando Salas, Aída Ribera, Ignacio Ferreira‐González, Hug Cuéllar, Víctor Pineda, Teresa González‐Alujas, Bart Bijnens, Gaietà Permanyer-Miralda, David García‐Dorado,

Background— Patent false lumen in aortic dissection has been associated with poor prognosis. We aimed to assess the natural evolution of this condition and predictive factors. Methods and Results— One hundred eighty-four consecutive patients, 108 surgically treated type A and 76 medically treated type B, were discharged after an acute aortic dissection with patent false lumen. Transesophageal echocardiography was performed before discharge, and computed tomography was performed at 3 months and yearly ...

Tópico(s): Cardiac Structural Anomalies and Repair

2012 - Lippincott Williams & Wilkins | Circulation

Artigo Acesso aberto Revisado por pares

Patrícia Ramos, Carla Pereira, Ana T. P. C. Gomes, Rodrigo T. Neto, Adelaide Almeida, Sónia A.O. Santos, Artur M. S. Silva, Armando J. D. Silvestre,

Agroforestry by-products have gained rising attention in recent years as they represent inexpensive and abundant raw materials that are a source of added-value chemicals, e.g., for food and pharmaceutical applications, as well as for bioenergy generation. Pinus pinaster Ait. bark extracts are consumed worldwide for their cardiovascular benefits, whilst the health potential of Pinus pinea L. bark has not yet been deeply exploited. Therefore, this study highlights the chemical characterisation of ...

Tópico(s): Thermochemical Biomass Conversion Processes

2022 - Multidisciplinary Digital Publishing Institute | Applied Sciences

Artigo Revisado por pares

Patrícia Ramos, Catarina Moreirinha, Sónia A.O. Santos, Adelaide Almeida, Carmen S. R. Freire, Artur M. S. Silva, Armando J. D. Silvestre,

Salix (Salicaceae) species bark extracts are traditionally consumed due to their anti-inflammatory and analgesic benefits, mainly attributed to phenolic compounds. However, this biomass could be further exploited calling upon other extractive components, namely the lipophilic fraction. Hence, the present study highlights, for the first time, the chemical characterisation and the inhibitory effect of S. viminalis L., S. atrocinerea Brot. and S. fragilis L. bark lipophilic dichloromethane extracts ...

Tópico(s): Natural product bioactivities and synthesis

2019 - Elsevier BV | Industrial Crops and Products

Artigo Acesso aberto Revisado por pares

Antoine S. Almeida, Rita Ferreira, Artur M. S. Silva, Armando C. Duarte, Bruno Miguel Neves, Regina M.B.O. Duarte,

The impact of inhalable fine particulate matter (PM2.5, aerodynamic diameter <2.5 μm) on public health is of great concern worldwide. Knowledge on their harmful effects are mainly due to studies carried out with whole air particles, with the contribution of their different fractions remaining largely unknown. Herein, a set of urban PM2.5 samples were collected during daytime and nighttime periods in autumn and spring, aiming to address the seasonal and day-night variability of water-soluble organic ...

Tópico(s): Air Quality Monitoring and Forecasting

2019 - American Chemical Society | Environmental Science & Technology

Artigo Acesso aberto Revisado por pares

Patrícia Ramos, Catarina Moreirinha, Sara Silva, Eduardo M. Costa, Mariana Veiga, Ezequiel R. Coscueta, Sónia A.O. Santos, Adelaide Almeida, Manuela Pintado, Carmen S. R. Freire, Artur M. S. Silva, Armando J. D. Silvestre,

Salix spp. have been exploited for energy generation, along with folk medicine use of bark extracts for antipyretic and analgesic benefits. Bark phenolic components, rather than salicin, have demonstrated interesting bioactivities, which may ensure the sustainable bioprospection of Salix bark. Therefore, this study highlights the detailed phenolic characterization, as well as the in vitro antioxidant, anti-hypertensive, Staphylococcus aureus growth inhibitory effects, and biocompatibility of Salix ...

Tópico(s): Ginkgo biloba and Cashew Applications

2019 - Multidisciplinary Digital Publishing Institute | Antioxidants

Artigo Acesso aberto Revisado por pares

Dina Rodrigues, Ana Rita Costa-Pinto, Sérgio Sousa, Marta W. Vasconcelos, Manuela Pintado, Leonel Pereira, Teresa Rocha‐Santos, João Pinto da Costa, Artur M. S. Silva, Armando C. Duarte, Ana Gomes, Ana C. Freitas,

Seaweeds, which have been widely used for human consumption, are considered a potential source of biological compounds, where enzyme-assisted extraction can be an efficient method to obtain multifunctional extracts. Chemical characterization of

Tópico(s): Echinoderm biology and ecology

2019 - Multidisciplinary Digital Publishing Institute | Marine Drugs

Artigo Acesso aberto Revisado por pares

Joana L. C. Sousa, Patrícia Ramos, Carmen S. R. Freire, Artur M. S. Silva, Armando J. D. Silvestre,

The chemical composition of lipophilic bark extracts from Pinus pinaster and Pinus pinea cultivated in Portugal was evaluated using gas chromatography-mass spectrometry. Diterpenic resin acids were found to be the main components of these lipophilic extracts, ranging from 0.96 g kg−1 dw in P. pinea bark to 2.35 g kg−1 dw in P. pinaster bark. In particular, dehydroabietic acid (DHAA) is the major constituent of both P. pinea and P. pinaster lipophilic fractions, accounting for 0.45 g kg−1 dw and 0. ...

Tópico(s): Plant biochemistry and biosynthesis

2018 - Multidisciplinary Digital Publishing Institute | Applied Sciences

Artigo Revisado por pares

Regina M.B.O. Duarte, M. Piñeiro-Iglesias, Purificación López-Mahı́a, Soledad Muniategui‐Lorenzo, Jorge Moreda–Piñeiro, Artur M. S. Silva, Armando C. Duarte,

This study investigates the structural composition and major sources of water-soluble organic matter (WSOM) from PM2.5 collected, in parallel, during summer and winter, in two contrasting suburban sites at Iberian Peninsula Coast: Aveiro (Portugal) and Coruña (Spain). PM10 samples were also collected at Coruña for comparison. Ambient concentrations of PM2.5, total nitrogen (TN), and WSOM were higher in Aveiro than in Coruña, with the highest levels found in winter at both locations. In Coruña, concentrations ...

Tópico(s): Atmospheric Ozone and Climate

2018 - Elsevier BV | The Science of The Total Environment

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Regina M.B.O. Duarte, João T.V. Matos, Andreia S. Paula, Sónia P. Lopes, Guilherme Martins Pereira, Pérola de Castro Vasconcellos, Adriana Gioda, Renato S. Carreira, Artur M. S. Silva, Armando C. Duarte, Patricia Smichowski, Néstor Y. Rojas, Odon Sánchez-Ccoyllo,

This study describes and compares the key structural units present in water-soluble organic carbon (WSOC) fraction of atmospheric aerosols collected in different South American (Colombia – Medellín and Bogotá, Peru – Lima, Argentina – Buenos Aires, and Brazil – Rio de Janeiro, São Paulo, and Porto Velho, during moderate (MBB) and intense (IBB) biomass burning) and Western European (Portugal – Aveiro and Lisbon) locations. Proton nuclear magnetic resonance (1H NMR) spectroscopy was employed to assess the relative ...

Tópico(s): Atmospheric aerosols and clouds

2017 - Elsevier BV | Environmental Pollution

Artigo Revisado por pares

João T.V. Matos, Regina M.B.O. Duarte, Sónia P. Lopes, Artur M. S. Silva, Armando C. Duarte,

Organic Aerosols (OAs) are typically defined as highly complex matrices whose composition changes in time and space. Focusing on time vector, this work uses two-dimensional nuclear magnetic resonance (2D NMR) techniques to examine the structural features of water-soluble (WSOM) and alkaline-soluble organic matter (ASOM) sequentially extracted from fine atmospheric aerosols collected in an urban setting during cold and warm seasons. This study reveals molecular signatures not previously decoded in NMR- ...

Tópico(s): Spectroscopy and Laser Applications

2017 - Elsevier BV | Environmental Pollution

Artigo Revisado por pares

Sónia P. Lopes, João T.V. Matos, Artur M. S. Silva, Armando C. Duarte, Regina M.B.O. Duarte,

Solution-state 1H NMR spectroscopy was applied to characterize the structural features of water- and alkaline-soluble organic matter (WSOM and ASOM, respectively) sequentially extracted from fine urban atmospheric aerosols collected over different seasons. The objectives of this study were twofold: (i) to compare the functional characteristics of fine aerosol WSOM and the yet unknown ASOM, and (ii) to assess the sources of WSOM and ASOM at an urban location. The 1H NMR analysis confirmed that the WSOM ...

Tópico(s): Air Quality Monitoring and Forecasting

2015 - Elsevier BV | Atmospheric Environment

Artigo Revisado por pares

Regina M.B.O. Duarte, Artur M. S. Silva, Armando C. Duarte,

The potential and the limitations of combining two-dimensional nuclear magnetic resonance (2D NMR) techniques to deliver new qualitative information on the substructures present in water-soluble organic compounds (WSOC) from fine atmospheric aerosols collected during Winter and Spring/Summer seasons are highlighted in this study. The WSOC fractions were extracted from quartz filter samples and further separated into hydrophobic acids and hydrophilic acids fractions by using a XAD-8/XAD-4 isolation ...

Tópico(s): Spectroscopy and Laser Applications

2008 - American Chemical Society | Environmental Science & Technology

Artigo Revisado por pares

Ana M. L. Seca, Artur M. S. Silva, Armando J. D. Silvestre, José A. S. Cavaleiro, Fernando M. J. Domingues, Carlos Pascoal Neto,

Four lignans, boehmenan H {2-(4-hydroxy-3-methoxyphenyl)-5-[3-(4-hydroxy-3-methoxycinnamoyloxy)propyl]-3-hydroxymethyl-7-methoxybenzodihydrofuran}, boehmenan K {2-(4-hydroxy-3-methoxyphenyl)-5-[3-(4-hydroxycinnamoyloxy)-1-propenyl]-3-(4-hydroxy-3-methoxycinnamoyloxymethyl)-7-methoxybenzodihydrofuran}, threo-carolignan H {threo-1-(4-hydroxy-3-methoxyphenyl)-2-{4-[3-(4-hydroxy-3-methoxycinnamoyloxy)propyl]-2-methoxyphenoxy}-1,3-propanodiol}, and threo-carolignan K {threo-1-(4-hydroxy-3-methoxyphenyl)- ...

Tópico(s): Hibiscus Plant Research Studies

2001 - Elsevier BV | Phytochemistry

Artigo Revisado por pares

Ana M. L. Seca, Artur M. S. Silva, Armando J. D. Silvestre, José A. S. Cavaleiro, Fernando M. J. Domingues, Carlos Pascoal Neto,

Two new acyclic phenylpropane lignanamides, grossamide K and erythro-canabisine H, and the naphthol glucoside 2,5-dimethyl-3-O-β-d-glucopyranosylnaphthol, along with six known compounds were isolated from the acetone extract of bark of Hibiscus cannabinus. All structures were established by spectroscopic methods including 2D NMR techniques, which allowed the correction of certain previously reported 13C NMR assignments of grossamide.

Tópico(s): Hibiscus Plant Research Studies

2001 - Elsevier BV | Phytochemistry

Artigo Revisado por pares

Ana M. L. Seca, Artur M. S. Silva, Armando J. D. Silvestre, José A. S. Cavaleiro, Fernando M. J. Domingues, Carlos Pascoal Neto,

GC/MS studies of the light petroleum extracts obtained from different morphological regions of kenaf (Hibiscus cannabinus) showed large differences between the composition of the bark and of the core. The non-polar lipid constituents were essentially fatty acids (30.7% in bark; 53.3% in core), long chain alcohols (19.3% in bark), alkanes (22.0% in bark), sterols (12.5% in bark; 25.4% in core) and triterpenes (11.2% in bark). Octacosanyl eicosanoate (15.7%) was detected only in the bark extract and was ...

Tópico(s): Magnolia and Illicium research

2000 - Wiley | Phytochemical Analysis

Artigo Acesso aberto Revisado por pares

Patrícia R. Pinto, Artur Vieira, Diamantino Pereira, Armando Almeida,

Abstract Acute postsurgical pain (APSP) is a common and anticipated problem after surgery with detrimental consequences if not appropriately managed. This study examined the independent and joint contribution of presurgical demographic, clinical, and psychological variables as predictors of APSP intensity, evaluated using an 11-point numeric rating scale, after inguinal hernioplasty, one of the most performed surgeries worldwide. In a prospective observational cohort study, a consecutive sample of 135 men ...

Tópico(s): Musculoskeletal pain and rehabilitation

2017 - Elsevier BV | Journal of Pain

Artigo Revisado por pares

Artur Mayerhofer, Andrzej Bartke, ARMANDO G. AMADOR AND TIM BEGAN,

Localization of mast cells in the testis and ability of histamine (HA) to stimulate testicular testosterone (T) production in vitro were examined in gonadally active adult golden hamsters, kept under a long daily photoperiod (LD) and in gonadally regressed adult golden hamsters exposed to an inhibitory short photoperiod (SD). In both groups mast cells were present in the capsule of the testes and occasionally in vicinity of intratesticular blood vessels. Histamine stimulated T production in a dose dependent ...

Tópico(s): Aquatic life and conservation

1989 - Oxford University Press | Endocrinology

Artigo Brasil Produção Nacional Revisado por pares

Bernardo Cassimiro Fonseca de Oliveira, Artur Antonio Seibert, Vicente K. Borges, Armando Albertazzi, Robert Schmitt,

Carbon fibre reinforced plastics (CFRPs) are replacing metals in fields such as aerospace due to their high mechanical strength and low weight. They have an anisotropic behaviour, which hinders the analysis of structural impairment caused by damages like impacts. Optical lock-in thermography (OLT) can be used to assess CFRP integrity and image processing tools can be applied to measure the area affected by impacts on the thermal images. There are several alternatives for segmenting those images and ...

Tópico(s): Infrared Target Detection Methodologies

2020 - Taylor & Francis | Nondestructive Testing And Evaluation

Artigo Revisado por pares

Dina Rodrigues, Ana C. Freitas, Sérgio Sousa, Manuela Amorim, Marta W. Vasconcelos, João Pinto da Costa, Artur M. S. Silva, Teresa Rocha‐Santos, Armando C. Duarte, Ana Gomes,

Edible mushrooms including Pholiota nameko are excellent sources of extractable bioactive compounds with much to explore. Enzymatic extractions with Cellulase and Viscozyme were responsible for highest extraction yields (67-77%). No strong antioxidant activity was observed although extracts were able to scavenge ABTS(+) and OH(+). Potential prebiotic activity was observed in all extracts, some increasing 1.4-2 Log cycles of Lactobacillus acidophilus La-5 and Bifidobacterium animalis BB12. 30-50% ...

Tópico(s): Microbial Metabolites in Food Biotechnology

2016 - Elsevier BV | Food Chemistry

Artigo Revisado por pares

Patrícia Ramos, Ângela R. Guerra, Olinda Guerreiro, Carmen S. R. Freire, Artur M. S. Silva, Maria F. Duarte, Armando J. D. Silvestre,

Lipophilic extracts of Cynara cardunculus L. var. altilis (DC) from the south of Portugal (Baixo Alentejo) were studied by gas chromatography–mass spectrometry. One sesquiterpene lactone, four pentacyclic triterpenes, and four sterols were reported for the first time as cultivated cardoon components, namely, deacylcynaropicrin, β- and α-amyrin, lupenyl and ψ-taraxasteryl acetates, stigmasterol, 24-methylenecholesterol, campesterol, and Δ5-avenasterol. In addition, other new compounds were identified: ...

Tópico(s): Botanical Studies and Applications

2013 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Brasil Produção Nacional Revisado por pares

Fernando Hallwass, Manuel Schmidt, Han Sun, Artur Mazur, Grit Kummerlöwe, Burkhard Luy, Armando Navarro‐Vázquez, Christian Griesinger, Uwe M. Reinscheid,

Gemeinsam stark: Eine neue Methode ermöglicht die zuverlässige Messung residualer chemischer Verschiebungsanisotropien (RCSAs) als zusätzliche NMR-spektroskopische Parameter für die Konformations- und Konfigurationsbestimmung kleiner Moleküle. Am Beispiel von Estron und 13-epi-Estron (siehe Strukturen) wird gezeigt, dass nur die gemeinsame Nutzung von RCSAs und dipolaren Restkopplungen zur eindeutigen Unterscheidung der beiden Diastereomere führt.

Tópico(s): Advanced NMR Techniques and Applications

2011 - Wiley | Angewandte Chemie

Artigo Brasil Produção Nacional Revisado por pares

Fernando Hallwass, Manuel Schmidt, Han Sun, Artur Mazur, Grit Kummerlöwe, Burkhard Luy, Armando Navarro‐Vázquez, Christian Griesinger, Uwe M. Reinscheid,

Together we are strong: A new, robust method allows the measurement of residual chemical shift anisotropies for the determination of conformation and configuration of molecules in organic solvents. The power of the method is shown by the example of estrone and 13-epi-estrone (see structures), where only the combined use of residual chemical shift anisotropies and residual dipolar couplings leads to the distinction of the two diastereomers. Detailed facts of importance to specialist readers are published ...

Tópico(s): Metabolomics and Mass Spectrometry Studies

2011 - Wiley | Angewandte Chemie International Edition

Artigo

Alexander G.G. Turpie, Alfredo E. Farjat, Sylvia Haas, Walter Ageno, Jeffrey I. Weitz, Samuel Z. Goldhaber, Shinya Goto, Pantep Angchaisuksiri, Gloria Kayani, Renato D. Lópes, Chern‐En Chiang, Harry Gibbs, Eric Tse, Peter Verhamme, Hugo Ten Cate, Juan Muntaner, Sebastian Schellong, Henri Bounameaux, Paolo Prandoni, Uma Maheshwari, Ajay K. Kakkar, A. Loualidi, Abdürrahim Çolak, Abraham F. Bezuidenhout, A.T.O. Abdool-Carrim, Addala Azeddine, Adriaan Beyers, A Dees, Ahmed Mohamed, Ahmet Aksoy, Akihiko Abiko, Akinori Watanabe, Alan Krichell, Alberto Alfredo Fernandez, Alberto Tosetto, Alexey Khotuntsov, Alisha Oropallo, Alison Slocombe, Allan Kelly, Amanda Clark, Amr Gad, Amy Arouni, Andor Schmidt, Andrea Berni, Andres Javier Kleiban, A Machowski, Andrey Kazakov, Ángel Gálvez, Ann Lockman, Anna Falanga, Anoop Chauhan, Antoni Riera‐Mestre, Antonino Mazzone, Armando D’Angelo, Artur Haddad Herdy, Atsushi Kato, Ayman Abd Elhamid Ebrahim Mahmoud Salem, Azlan Husin, Barbara Erdelyi, Barry Jacobson, Beatrice Amann‐Vesti, Bektaş Battaloğlu, Benedicte Wilson, Benilde Cosmi, Bergmann Jean Francois, Berremeli Toufek, Beverley Hunt, Bhavesh Natha, Bisher Mustafa, Bonnie Chi Shan Kho, Boulon Carine, Brian Zidel, Brisot Dominique, Brousse Christophe, Bruno Trimarco, Canhua Luo, Carlos Alberto Cuneo, Carlos Jerjes‐Sánchez, Carsten Schwencke, Cas Cader, Celal Yavuz, Cesar Javier Zaidman, Charles A. Lunn, Chau‐Chung Wu, Cheng Hock Toh, Chern‐En Chiang, Chevrier Elisa, Chien‐Hsun Hsia, Chien-Lung Huang, Chi‐Hang Kevin Kwok, Chih-Cheng Wu, Chi‐Hung Huang, Chris Ward, Christian Opitz, Christina Jeanneret‐Gris, Chung Yin Ha, Chun‐Yao Huang, Claude Luyeye Bidi, Clifford Smith, Cornelia Brauer, Corrado Lodigiani, Françis Couturaud, Cynthia Wu, Daniel Staub, Daniel Theodoro, Daniela Poli, David Acevedo, David Adler, David Jiménez, David Keeling, David Scott, Davide Imberti, Desmond Creagh, Desmurs‐Clavel Helene, Dirk Hagemann, Dirk Le Roux, Dirk Skowasch, Dmitry Belenky, Dmitry Dorokhov, Dmitry Petrov, D. A. Zateyshchikov, Domenico Prisco, Dorthe Svenstrup Møller, Dusan Kucera, Ehab M. Esheiba, Е. П. Панченко, Elkouri Dominique, Emre Doğan, Emre Kubat, Enrique Diaz Diaz, Eric Wai Choi Tse, Erik Yeo, Erman Hashas, Ernst Gröchenig, Eros Tiraferri, Erwin Blessing, E Michele, Esther Usandizaga, Ettore Porreca, Fabián Ferroni, Falvo Nicolas, Félix Ayala-Paredes, Firas Koura, Fitjerald Henry, Franco Cosmi, Frans Erdkamp, Gadel Kamalov, Garcia‐Bragado Dalmau, Garrigues Damien, Garry Klein, Gaurand Shah, Geert Hollanders, Geno J. Merli, Georg Plassmann, George Platt, Germain Poirier, German Sokurenko, Ghassan Haddad, Gholam Ali, Giancarlo Agnelli, Gin Gin Gan, Grace Kaye‐Eddie, Grégoire Le Gal, Gregory Allen, Guillermo Antonio Llamas Esperón, Guillot Jean‐Paul, Hagen Gerofke, Hallah Elali, Hana Burianová, Hans‐Juergen Ohler, Haofu Wang, Harald Darius, Harinder Gogia, Harry Striekwold, Harry Gibbs, Hatice Canan Hasanoğlu, Hatice Türker, Hendrik Franow, Henri Bounameaux, Herbert De Raedt, Herman Schroë, Hesham Salah ElDin, Hesham Zidan, Hiroaki Nakamura, Ho Young Kim, Holger Lawall, Hong Zhu, Hongyan Tian, Ho‐Young Yhim, Hugo Ten Cate, Hun-Gyu Hwang, Hyeok Shim, Igor Kim, И. А. Либов, Igor Sonkin, I.А. Suchkov, Ik‐Chan Song, İlker Kiriş, И Н Староверов, Irene Looi, Isabel M. De La Azuela Tenorio, İsmail Savaş, И. Г. Гордеев, Ivo Podpera, Jae Hoon Lee, Jameela Sathar, James Welker, Jan Beyer‐Westendorf, J Kvasnička, Jan Vanwelden, J.I. Kim, Jaromira Svobodova, Jaspal Gujral, Javier Marino, Javier Tristan Galvar, Jeannine Kassis, Jen‐Yuan Kuo, Jhih-Yuan Shih, Jihyun Kwon, Jin Hyun Joh, Jin Hyun Park, Jin Seok Kim, Jinghua Yang, J Krupicka, Jiří Laštůvka, Jiri Pumprla, Jiří Veselý, Juan Carlos Souto, João Antônio Corrêa, Johan Duchateau, John Perry Fletcher, J. del Toro, J. del Toro, Jorge Guillermo Chavez Paez, Jørn Dalsgaard Nielsen, Jose Dalmo Araujo Filho, José Francisco Kerr Saraiva, José Antonio Díaz Peromingo, Jose Lara, José Luis Fedele, José María Suriñach, Joseph Chacko, Juan Muntaner, Juan Carlos Álvarez Benitez, Juan Moreno Hoyos Abril, Julian Humphrey, Julio Bono, Junji Kanda, Juree Boondumrongsagoon, Kai Hang Yiu, Kanchana Chansung, Karin A. Boomars, Kate Burbury, Katsuhiro Kondo, Kemal Karaarslan, Kensuke Takeuchi, Knut Kroeger, Konstantin Zrazhevskiy, Koscál Svatopluk, Kou‐Gi Shyu, Kristel Vandenbosch, Kuan‐Cheng Chang, Kuan‐Ming Chiu, Kubina Jean‐Manuel, Zhi‐Cheng Jing, Kwo‐Chang Ueng, Lalita Norasetthada, L Binet, Lee Ping Chew, Lei Zhang, Leone Maria Cristina, Lidwine W. Tick, Lilia Beatriz Schiavi, Lily Lee Lee Wong, Lohana Borges, Louis Botha, Luc Capiau, Luc Timmermans, Luciano Eduardo López, Luigi Ria, Luis Blasco, Luis Alberto Guzman, Luis Flota Cervera, Mahe Isabelle, Manuel Monreal Bosch, Manuel de los Rios Ibarra, Manuel Núñez Fernandez, Marc Carrier, Marcelo Barrionuevo, Marco Antonio Alcocer Gamba, Marco Cattaneo, Marco Moia, Margaret Bowers, Mariam Chetanachan, Mario Alberto Berli, Mark Fixley,

Venous thromboembolism (VTE), encompassing both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a leading cause of morbidity and mortality worldwide.GARFIELD-VTE is a prospective, non-interventional observational study of real-world treatment practices. We aimed to capture the 36-month clinical outcomes of 10,679 patients with objectively confirmed VTE enrolled between May 2014 and January 2017 from 415 sites in 28 countries.A total of 6582 (61.6 %) patients had DVT alone, 4097 (38.4 %) had PE ± DVT. ...

Elsevier BV

Artigo

Jeffrey I. Weitz, Sylvia Haas, Walter Ageno, Samuel Z. Goldhaber, Alexander G.G. Turpie, Shinya Goto, Pantep Angchaisuksiri, Jørn Dalsgaard Nielsen, Gloria Kayani, Alfredo E. Farjat, Sebastian Schellong, Henri Bounameaux, LG Mantovani, Paolo Prandoni, Ajay K. Kakkar, A. Loualidi, Abdürrahim Çolak, Abraham F. Bezuidenhout, A.T.O. Abdool-Carrim, Addala Azeddine, Adriaan Beyers, A Dees, Ahmed Mohamed, Ahmet Aksoy, Akihiko Abiko, Akinori Watanabe, Alan Krichell, Alberto Alfredo Fernandez, Alberto Tosetto, Alexey Khotuntsov, Alisha Oropallo, Alison Slocombe, Allan Kelly, Amanda Clark, Amr Gad, Amy Arouni, Andor Schmidt, Andrea Berni, Andres Javier Kleiban, A Machowski, Andrey Kazakov, Ángel Gálvez, Ann Lockman, Anna Falanga, Anoop Chauhan, Antoni Riera‐Mestre, Antonino Mazzone, Armando D’Angelo, Artur Haddad Herdy, Atsushi Kato, Ayman Abd Elhamid Ebrahim Mahmoud Salem, Azlan Husin, Barbara Erdelyi, Barry Jacobson, Beatrice Amann‐Vesti, Bektaş Battaloğlu, Benedicte Wilson, Benilde Cosmi, Bergmann Jean Francois, Berremeli Toufek, Beverley J. Hunt, Bhavesh Natha, Bisher Mustafa, Bonnie Chi Shan Kho, Boulon Carine, Brian Zidel, Brisot Dominique, Brousse Christophe, Bruno Trimarco, Canhua Luo, Carlos Alberto Cuneo, Carlos Jerjes‐Sánchez, Carsten Schwencke, Cas Cader, Celal Yavuz, Cesar Javier Zaidman, Charles A. Lunn, Chau‐Chung Wu, Cheng Hock Toh, Chern‐En Chiang, Chevrier Elisa, Chien‐Hsun Hsia, Chien-Lung Huang, Chi‐Hang Kevin Kwok, Chih-Cheng Wu, Chi‐Hung Huang, Chris Ward, Christian Opitz, Christina Jeanneret‐Gris, Chung Yin Ha, Chun‐Yao Huang, Claude Luyeye Bidi, Clifford Smith, Cornelia Brauer, Corrado Lodigiani, Françis Couturaud, Cynthia Wu, Daniel Staub, Daniel Theodoro, Daniela Poli, David Acevedo, David Adler, David Jiménez, David Keeling, David Scott, Davide Imberti, Desmond Creagh, Desmurs‐Clavel Helene, Dirk Hagemann, Dirk Le Roux, Dirk Skowasch, Dmitry Belenky, Dmitry Dorokhov, Dmitry Petrov, D. A. Zateyshchikov, Domenico Prisco, Dorthe Svenstrup Møller, Dusan Kucera, Ehab M. Esheiba, Е. П. Панченко, Elkouri Dominique, Emre Doğan, Emre Kubat, Enrique Diaz Diaz, Eric Wai Choi Tse, Erik Yeo, Erman Hashas, Ernst Gröchenig, Eros Tiraferri, Erwin Blessing, E Michele, Esther Usandizaga, Ettore Porreca, Fabián Ferroni, Falvo Nicolas, Félix Ayala-Paredes, Firas Koura, Fitjerald Henry, Franco Cosmi, Frans Erdkamp, Gadel Kamalov, Garcia‐Bragado Dalmau, Garrigues Damien, Garry Klein, Gaurand Shah, Geert Hollanders, Geno J. Merli, Georg Plassmann, George Platt, Germain Poirier, German Sokurenko, Ghassan Haddad, Gholam Ali, Giancarlo Agnelli, Gin Gin Gan, Grace Kaye‐Eddie, Grégoire Le Gal, Gregory Allen, Guillermo Antonio Llamas Esperón, Guillot Jean‐Paul, Hagen Gerofke, Hallah Elali, Hana Burianová, Hans‐Juergen Ohler, Haofu Wang, Harald Darius, Harinder Gogia, Harry Striekwold, Harry Gibbs, Hatice Canan Hasanoğlu, Hatice Türker, Hendrik Franow, Henri Bounameaux, Herbert De Raedt, Herman Schroë, Hesham Salah ElDin, Hesham Zidan, Hiroaki Nakamura, Ho Young Kim, Holger Lawall, Hong Zhu, Hongyan Tian, Ho-Young Yhim, Hugo Ten Cate, Hun-Gyu Hwang, Hyeok Shim, Igor Kim, И. А. Либов, Igor Sonkin, I.А. Suchkov, Ik‐Chan Song, İlker Kiriş, И Н Староверов, Irene Looi, Isabel M. De La Azuela Tenorio, İsmail Savaş, И. Г. Гордеев, Ivo Podpera, Jae Hoon Lee, Jameela Sathar, James Welker, Jan Beyer‐Westendorf, J Kvasnička, Jan Vanwelden, J.I. Kim, Jaromira Svobodova, Jaspal Gujral, Javier Marino, Javier Tristan Galvar, Jeannine Kassis, Jen‐Yuan Kuo, Jhih-Yuan Shih, Jihyun Kwon, Jin Hyun Joh, Jin Hyun Park, Jin Seok Kim, Jinghua Yang, J Krupicka, Jiří Laštůvka, Jiri Pumprla, Jiří Veselý, Juan Carlos Souto, João Antônio Corrêa, Johan Duchateau, John Perry Fletcher, J. del Toro, J. del Toro, Jorge Guillermo Chavez Paez, Jørn Dalsgaard Nielsen, Jose Dalmo Araujo Filho, Jose F. Kerr Saraiva, José Antonio Díaz Peromingo, Jose Lara, José Luis Fedele, José María Suriñach, Joseph Chacko, Juan Muntaner, Juan Carlos Álvarez Benitez, Juan Moreno Hoyos Abril, Julian Humphrey, Julio Bono, Junji Kanda, Juree Boondumrongsagoon, Kai Hang Yiu, Kanchana Chansung, Karin A. Boomars, Kate Burbury, Katsuhiro Kondo, Kemal Karaarslan, Kensuke Takeuchi, Knut Kroeger, Konstantin Zrazhevskiy, Koscál Svatopluk, Kou‐Gi Shyu, Kristel Vandenbosch, Kuan‐Cheng Chang, Kuan‐Ming Chiu, Kubina Jean‐Manuel, Zhi‐Cheng Jing, Kwo‐Chang Ueng, Lalita Norasetthada, L Binet, Lee Ping Chew, Lei Zhang, Leone Maria Cristina, Lidwine W. Tick, Lilia Beatriz Schiavi, Lily Lee Lee Wong, Lohana Borges, Louis Botha, Luc Capiau, Luc Timmermans, Luciano Eduardo López, Luigi Ria, Luis Blasco, Luis Alberto Guzman, Luis Flota Cervera, Mahe Isabelle, Manuel Monreal Bosch, Manuel de los Rios Ibarra, Manuel Núñez Fernandez, Marc Carrier, Marcelo Barrionuevo, Marco Antonio Alcocer Gamba, Marco Cattaneo, Marco Moia, Margaret Bowers, Mariam Chetanachan, Mario Alberto Berli, Mark Fixley, Markus Faghih, Markus Stüecker, Marlin Schul, Martin Banyai, Martín Koretzky, Martin Myriam,

Springer Science+Business Media

Artigo

Sylvia Haas, Walter Ageno, Jeffrey I. Weitz, Samuel Z. Goldhaber, Alexander G.G. Turpie, Shinya Goto, Pantep Angchaisuksiri, Joern Dalsgaard Nielsen, Gloria Kayani, Audrey Zaghdoun, Alfredo E. Farjat, Sebastian Schellong, Henri Bounameaux, LG Mantovani, Paolo Prandoni, Ajay K. Kakkar, A. Loualidi, Abdürrahim Çolak, Abraham F. Bezuidenhout, A.T.O. Abdool-Carrim, Addala Azeddine, Adriaan Beyers, A Dees, Ahmed Mohamed, Ahmet Aksoy, Akihiko Abiko, Akinori Watanabe, Alan Krichell, Alberto Alfredo Fernandez, Alberto Tosetto, Alexey Khotuntsov, Alisha Oropallo, Alison Slocombe, Allan Kelly, Amanda Clark, Amr Gad, Amy Arouni, Andor Schmidt, Andrea Berni, Andres Javier Kleiban, A Machowski, Andrey Kazakov, Ángel Gálvez, Ann Lockman, Anna Falanga, Anoop Chauhan, Antoni Riera‐Mestre, Antonino Mazzone, Armando D’Angelo, Artur Haddad Herdy, Atsushi Kato, Ayman Abd Elhamid Ebrahim, Mahmoud Salem, Azlan Husin, Barbara Erdelyi, Barry Jacobson, Beatrice Amann‐Vesti, Bektaş Battaloğlu, Benedicte Wilson, Benilde Cosmi, Bergmann Jean Francois, Berremeli Toufek, Beverley Hunt, Bhavesh Natha, Bisher Mustafa, Bonnie Chi Shan Kho, Boulon Carine, Brian Zidel, Brisot Dominique, Brousse Christophe, Bruno Trimarco, Canhua Luo, Carlos Alberto Cuneo, Carlos Jerjes‐Sánchez, Carsten Schwencke, Cas Cader, Celal Yavuz, Cesar Javier Zaidman, Charles A. Lunn, Chau‐Chung Wu, Cheng Hock Toh, Chern‐En Chiang, Chevrier Elisa, Chien‐Hsun Hsia, Chien‐Lung Huang, Chi‐Hang Kevin Kwok, Chih‐Cheng Wu, Chi‐Hung Huang, Chris Ward, Christian Opitz, Christina Jeanneret‐Gris, Chung Yin Ha, Chun‐Yao Huang, Claude Luyeye Bidi, Clifford Smith, Cornelia Brauer, Corrado Lodigiani, Françis Couturaud, Cynthia Wu, Daniel Staub, Daniel Theodoro, D. Poli, Riesco Acevedo, David Adler, David Jiménez, David Keeling, David Scott, Davide Imberti, Desmond Creagh, Desmurs‐Clavel Helene, Dirk Hagemann, Dirk Le Roux, Dirk Skowasch, Dmitry Belenky, Dmitry Dorokhov, Dmitry Petrov, D. A. Zateyshchikov, Domenico Prisco, Dorthe Svenstrup Møller, Dusan Kucera, Ehab M. Esheiba, Е. П. Панченко, Elkouri Dominique, Emre Doğan, Emre Kubat, Enrique Diaz Diaz, Eric Wai Choi Tse, Erik Yeo, Erman Hashas, Ernst Gröchenig, Eros Tiraferri, Erwin Blessing, E Michele, Esther Usandizaga, Ettore Porreca, Fabián Ferroni, Falvo Nicolas, F. Ayala‐Paredes, Firas Koura, Fitjerald Henry, Franco Cosmi, Frans Erdkamp, Gadel Kamalov, Garcia‐Bragado Dalmau, Garrigues Damien, Garry Klein, Gaurand Shah, Geert Hollanders, Geno J. Merli, Georg Plassmann, George Platt, Germain Poirier, German Sokurenko, Ghassan Haddad, Gholam Ali, Giancarlo Agnelli, Gin Gin Gan, Grace Kaye‐Eddie, Grégoire Le Gal, Gregory Allen, Guillermo Antonio Llamas Esperón, Guillot Jean‐Paul, Hagen Gerofke, Hallah Elali, Hana Burianová, Hans‐Juergen Ohler, Haofu Wang, Harald Darius, Harinder Gogia, Harry Striekwold, Harry Gibbs, Hatice Canan Hasanoğlu, Hatice Türker, Hendrik Franow, Herbert De Raedt, Herman Schroë, Hesham Salah ElDin, Hesham Zidan, Hiroaki Nakamura, Ho Young Kim, Holger Lawall, Hong Zhu, Hongyan Tian, Ho‐Young Yhim, Hugo Ten Cate, Hun-Gyu Hwang, Hyeok Shim, Igor Kim, И. А. Либов, Igor Sonkin, I.А. Suchkov, Ik‐Chan Song, İlker Kiriş, И Н Староверов, Irene Looi, Isabel M. De La Azuela Tenorio, İsmail Savaş, И. Г. Гордеев, Ivo Podpera, Jae Hoon Lee, Jameela Sathar, James Welker, Jan Beyer‐Westendorf, J Kvasnička, Jan Vanwelden, J.I. Kim, Jaromira Svobodova, Jaspal Gujral, Javier Marino, Javier Tristan Galvar, Jeannine Kassis, Jen‐Yuan Kuo, Jhih‐Yuan Shih, Jihyun Kwon, Jin Hyun Joh, Jin Hyun Park, Jin Seok Kim, Jinghua Yang, J Krupicka, Jiří Laštůvka, Jiri Pumprla, Jiří Veselý, Juan Carlos Souto, João Antônio Corrêa, Johan Duchateau, John Perry Fletcher, J. del Toro, J. del Toro, Jorge Guillermo Chavez Paez, Jose Dalmo Araujo Filho, José Francisco Kerr Saraiva, José Antonio Díaz Peromingo, Jose Lara, José Luis Fedele, José María Suriñach, Joseph Chacko, Juan Muntaner, Juan Carlos Álvarez Benitez, Juan Moreno Hoyos Abril, Julian Humphrey, Julio Bono, Junji Kanda, Juree Boondumrongsagoon, Kai Hang Yiu, Kanchana Chansung, Karin A. Boomars, Kate Burbury, Katsuhiro Kondo, Kemal Karaarslan, Kensuke Takeuchi, Knut Kroeger, Konstantin Zrazhevskiy, Koscál Svatopluk, Kou‐Gi Shyu, Kristel Vandenbosch, Kuan‐Cheng Chang, Kuan‐Ming Chiu, Kubina Jean‐Manuel, Zhi‐Cheng Jing, Kwo‐Chang Ueng, Lalita Norasetthada, L Binet, Lee Ping Chew, Lei Zhang, Leone Maria Cristina, Lidwine W. Tick, Lilia Beatriz Schiavi, Lily Lee Lee Wong, Lohana Borges, Louis Botha, Luc Capiau, Luc Timmermans, Luciano Eduardo López, Luigi Ria, Luis Blasco, Luis Alberto Guzman, Luis Flota Cervera, Mahe Isabelle, Manuel Monreal Bosch, Manuel de los Rios Ibarra, Manuel Núñez Fernandez, Marc Carrier, Marcelo Barrionuevo, Marco Antonio Alcocer Gamba, Marco Cattaneo, Marco Moia, Margaret Bowers, Mariam Chetanachan, Mario Alberto Berli, Mark Fixley, Markus Faghih, Markus Stüecker, Marlin Schul, Martin Banyai, Martín Koretzky, Martin Myriam,

Parenteral anticoagulants and vitamin K antagonists (VKAs) have constituted the cornerstone of venous thromboembolism (VTE) treatment. Meanwhile, direct oral anticoagulants (DOACs) provide physicians with an alternative. The Global Anticoagulant Registry in the FIELD (GARFIELD)-VTE observes real-world treatment practices.Describe initial anticoagulation (AC) treatment patterns in VTE patients who received parenteral AC, VKAs, and/or DOACs within ±30 days of diagnosis.VTE patients were categorized into ...

Elsevier BV

Artigo Acesso aberto Revisado por pares

Cátia S. D. Oliveira, Patrícia Moreira, Judite Resende, Maria Teresa Cruz, Cláudia Pereira, Artur M. S. Silva, Sónia A.O. Santos, Armando J. D. Silvestre,

Acacia dealbata biomass, either from forest exploitation or from the management of invasive species, can be a strategic topic, namely as a source of high-value compounds. In this sense, the present study aimed at the detailed characterization of the lipophilic components of different morphological parts of A. dealbata and the evaluation of their cytotoxicity in cells representative of different mammals' tissues. The chemical composition of lipophilic extracts from A. dealbata bark, wood and leaves ...

Tópico(s): Essential Oils and Antimicrobial Activity

2020 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences

Revisão Acesso aberto Revisado por pares

Joana L. C. Sousa, Carmen S. R. Freire, Armando J. D. Silvestre, Artur M. S. Silva,

Betulinic acid (BA) and its natural analogues betulin (BN), betulonic (BoA), and 23-hydroxybetulinic (HBA) acids are lupane-type pentacyclic triterpenoids. They are present in many plants and display important biological activities. This review focuses on the chemical transformations used to functionalize BA/BN/BoA/HBA in order to obtain new derivatives with improved biological activity, covering the period since 2013 to 2018. It is divided by the main chemical transformations reported in the literature, ...

Tópico(s): Phytochemical compounds biological activities

2019 - Multidisciplinary Digital Publishing Institute | Molecules

Artigo Acesso aberto Revisado por pares

Lúcia Oliveira, Dmitry V. Evtuguin, Nereida Cordeiro, Armando J. D. Silvestre, Artur M. S. Silva, Isabel Torres,

Dioxane lignin (DL) isolated from leaf sheaths of banana plant (Musa acuminata Colla var. cavendish) and in situ lignin were submitted to a comprehensive structural characterization employing spectroscopic (UV, FTIR, solid state 13C CP-MAS NMR, liquid state 13C and 1H NMR) and chemical degradation techniques (permanganate and nitrobenzene oxidation). Results obtained showed that banana plant leaf sheath lignin is of HGS type with a molar proportion of p-hydroxyphenyl (H)/guaiacyl (G)/syringyl (S) units ...

Tópico(s): Plant Gene Expression Analysis

2006 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Revisado por pares

Susana Isabel Pereira, Carmen S. R. Freire, Carlos Pascoal Neto, Armando J. D. Silvestre, Artur M. S. Silva,

The chemical composition of the essential oil of the fruits collected from Eucalyptus globulus trees grown in Portugal has been studied; 33 components were identified, representing 94.5% of the oil, which comprises roughly equal amounts of monoterpenes (50.4%) and sesquiterpenes (49.6%). The major components identified were aromadendrene (25.1%), followed by α-phellandrene (17.2%), 1,8-cineole (11.7%), ledene (5.83%) and globulol (5.23%). Copyright © 2005 John Wiley & Sons, Ltd.

Tópico(s): Natural product bioactivities and synthesis

2005 - Wiley | Flavour and Fragrance Journal