Arnold R. Palacios, Luca Morgantini, Ryan Trippel, Simone Crivellaro, Michael R. Abern,
Objective: To report early institutional experience with the single-port robotic platform and compare perioperative outcomes between single-port robot-assisted partial nephrectomies (SP-RAPN) and multiport robot-assisted partial nephrectomies (MP-RAPN) when utilizing a retroperitoneal approach. Methods: A retrospective chart review of patients who underwent SP-RAPN or MP-RAPN at our institution between November 1, 2013 and May 30, 2021 was performed. Surgical platforms were compared through univariate ...
Tópico(s): Minimally Invasive Surgical Techniques
2022 - Mary Ann Liebert, Inc. | Journal of Endourology
Maham Rais, Jonathan W. Lovelace, Xinghao S. Shuai, Walker Woodard, Steven Bishay, Leo Estrada, Ashwin R. Sharma, Austin Nguy, Anna Kulinich, Patricia S. Pirbhoy, Arnold R. Palacios, David L. Nelson, Khaleel A. Razak, Iryna M. Ethell,
Fragile X syndrome (FXS) is a leading genetic cause of autism and intellectual disability with cortical hyperexcitability and sensory hypersensitivity attributed to loss and hypofunction of inhibitory parvalbumin-expressing (PV) cells. Our studies provide novel insights into the role of excitatory neurons in abnormal development of PV cells during a postnatal period of inhibitory circuit refinement.To achieve Fragile X mental retardation gene (Fmr1) deletion and re-expression in excitatory neurons ...
Tópico(s): Congenital heart defects research
2021 - Elsevier BV | Neurobiology of Disease
Jonathan W. Lovelace, Maham Rais, Arnold R. Palacios, Xinghao S. Shuai, Steven Bishay, Otilia Popa, Patricia S. Pirbhoy, Devin K. Binder, David L. Nelson, Iryna M. Ethell, Khaleel A. Razak,
Fragile X syndrome (FXS) is a leading genetic cause of autism with symptoms that include sensory processing deficits. In both humans with FXS and a mouse model [Fmr1 knockout (KO) mouse], electroencephalographic (EEG) recordings show enhanced resting state gamma power and reduced sound-evoked gamma synchrony. We previously showed that elevated levels of matrix metalloproteinase-9 (MMP-9) may contribute to these phenotypes by affecting perineuronal nets (PNNs) around parvalbumin (PV) interneurons in the ...
Tópico(s): Congenital heart defects research
2019 - Oxford University Press | Cerebral Cortex
Teresa H. Wen, Sonia Afroz, Sarah M. Reinhard, Arnold R. Palacios, Kendal Tapia, Devin K. Binder, Khaleel A. Razak, Iryna M. Ethell,
Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli. Similar sensory deficits are also observed in adult Fmr1 knock-out (KO) mice and are reversed by genetic deletion of Matrix Metalloproteinase-9 (MMP-9) through yet unknown mechanisms. Here we present new evidence that impaired development of parvalbumin (PV)-expressing inhibitory interneurons may underlie hyper-responsiveness in auditory ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2017 - Oxford University Press | Cerebral Cortex
John B. Ruedas, Catherine Arnold, Gustavo Palacios, John H. Connor,
Zaire ebolavirus (EBOV) is the causative agent of the highly lethal Ebola virus disease and poses a significant threat to the global health community. Approved antivirals against EBOV are lacking; however, promising therapies targeting the EBOV glycoprotein are being developed. Efficacy testing of these candidate therapeutics relies on EBOV laboratory stocks, which when grown in tissue culture may acquire mutations in the glycoprotein. These mutations can produce inaccurate results in therapeutic ...
Tópico(s): Hepatitis B Virus Studies
2018 - American Society for Microbiology | Journal of Virology
Benjamin N. Schmeusser, Arnold R. Palacios, Eric Midenberg, Reza Nabavizadeh, Dattatraya Patil, R. Donald Harvey, Janetta Bryksin, Michael Connor, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
Abstract Background Black patients face disparities in cancer outcomes. Additionally, Black patients are more likely to be undertreated and underrepresented in clinical trials. The recent recommendation to remove race from the estimated glomerular filtration rate (eGFR) results in lower eGFR values for Black patients. The ramifications of this decision, both intended and unintended, are still being elucidated in the medical community. Here, the authors analyze the removal of race from eGFR for Black ...
Tópico(s): MRI in cancer diagnosis
2023 - Wiley | Cancer
Viraj A. Master, Benjamin N. Schmeusser, Adeboye O. Osunkoya, Arnold R. Palacios, Eric Midenberg, Lauren Yantorni, Kenneth Ogan, Mehmet Asım Bilen,
ABSTRACT Renal cell carcinoma with level IV tumor thrombus is a condition necessitating aggressive surgical management. Many solid organ malignancies often benefit from neoadjuvant treatments for tumor debulking and improvement of surgical outcomes. However, neoadjuvant treatments for renal cell carcinoma have been limited by its resistance to traditional chemotherapy and radiation. Emerging treatment modalities, such as immunotherapies, are exciting new options that may be therapeutically effective. ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2022 - | Journal of Immunotherapy and Precision Oncology
Faisal Akram, Kyle N. Kunze, Benjamin Kerzner, Alejandro González, Arnold R. Palacios, Brett R. Levine,
Background Femoral stem subsidence is a known cause of early implant failure, increasing the risk for aseptic loosening and periprosthetic fracture. Overall survivorship and subsidence in a novel porous tantalum-coated femoral prosthesis have not been well-studied. Methods Consecutive patients undergoing primary total hip arthroplasty with a porous tantalum-coated femoral prosthesis between January 2008 and January 2015 with minimum 5-year follow-up were included. Clinical and radiographic data ...
Tópico(s): Orthopedic Infections and Treatments
2020 - Elsevier BV | The Journal of Arthroplasty
Irene Palacios, Christine Arnold,
The Lisbon Treaty introduced key institutional changes to increase the relevance of elections to the European Parliament (EP). Among these was the ‘Spitzenkandidaten process’, which was introduced with the aim to increase the visibility of the EP elections and mobilise more citizens to turnout to vote. This article investigates the effect that the debates among the Lead Candidates had on voters’ perceptions about candidates and policy issues. To do this, we administered a two-wave panel online survey ...
Tópico(s): Public Administration and Political Analysis
2021 - SAGE Publishing | Politics
Arnold R. Palacios, Benjamin N. Schmeusser, Eric Midenberg, Dattatraya Patil, Lillian Xie, Reza Nabavizadeh, Kenneth Ogan, Kenneth Cardona, Shishir K. Maithel, Viraj A. Master,
Abstract Background and Objectives Retroperitoneal tumors with involvement of the inferior vena cava (IVC) often require resection of the IVC to achieve complete tumor removal. This study evaluates the safety and efficacy of IVC ligation without caval reconstruction. Methods A retrospective chart review of patients who underwent IVC ligation (IVC‐Ligation) and IVC resection with reconstruction (IVC‐Reconstruction) at our institution between May 2004 and April 2021 was performed. Outcomes from the two ...
Tópico(s): Renal cell carcinoma treatment
2022 - Wiley | Journal of Surgical Oncology
Edouard Nicaise, Benjamin N. Schmeusser, Adil Ali, Eric Midenberg, Arnold R. Palacios, Ethan Kearns, Sriram Ambadi, Sarah P. Psutka, Bassel Nazha, Jacqueline T. Brown, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
... Nicaise, Benjamin N. Schmeusser, Adil Ali, Eric Midenberg, Arnold R. Palacios, Ethan Kearns, Sriram Ambadi, Sarah P. Psutka, Bassel ... author Eric Midenberg More articles by this author Arnold R. Palacios More articles by this author Ethan Kearns More ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2024 - Lippincott Williams & Wilkins | The Journal of Urology
Saikat Nandi, Étienne Plésiat, Shiyang Zhong, Alicia Palacios, David Busto, Marcus Isinger, Lana Neoričić, Cord L. Arnold, Richard J. Squibb, R. Feifel, P. Decleva, A. L’Huillier, Fernando Martı́n, Mathieu Gisselbrecht,
Shape resonances in physics and chemistry arise from the spatial confinement of a particle by a potential barrier. In molecular photoionization, these barriers prevent the electron from escaping instantaneously, so that nuclei may move and modify the potential, thereby affecting the ionization process. By using an attosecond two-color interferometric approach in combination with high spectral resolution, we have captured the changes induced by the nuclear motion on the centrifugal barrier that sustains ...
Tópico(s): Advanced Chemical Physics Studies
2020 - American Association for the Advancement of Science | Science Advances
Maneesh Dave, Luca Di Martino, Rodrigo A. Somoza, Alexander Rodriguez‐Palacios, Arnold I. Caplan, Fabio Cominelli,
2016 - Elsevier BV | Gastroenterology
Benjamin N. Schmeusser, Arnold R. Palacios, Shishir K. Maithel, Viraj A. Master,
... Search for more papers by this authorArnold R. Palacios MD, MA, Arnold R. Palacios MD, MA Department of Urology, Emory ... Search for more papers by this authorArnold R. Palacios MD, MA, Arnold R. Palacios MD, MA Department of Urology, Emory University School ...
Tópico(s): Prostate Cancer Diagnosis and Treatment
2022 - Wiley | Journal of Surgical Oncology
Arnold R. Palacios, Luca Morgantini, Ryan Trippel, Simone Crivellaro, Michael Abern,
... PORT AND MULTIPORT RETROPERITONEAL ROBOT-ASSISTED PARTIAL NEPHRECTOMIES Arnold Palacios, Luca Morgantini, Ryan Trippel, Simone Crivellaro, and Michael ... Urological Association Education and Research, Inc.MetricsAuthor Information Arnold Palacios More articles by this author Luca Morgantini More ...
Tópico(s): Bladder and Urothelial Cancer Treatments
2022 - Lippincott Williams & Wilkins | The Journal of Urology
Benjamin N. Schmeusser, Eric Midenberg, Arnold R. Palacios, Nikhil Vettikattu, Dattatraya Patil, A Medline, Michelle Higgins, Manuel Armas‐Phan, Reza Nabavizadeh, Shreyas Joshi, Vikram M. Narayan, Sarah P. Psutka, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
Purpose Sarcopenia is associated with decreased survival and increased complications in patients with renal cell carcinoma. Readily identifying patients with low muscle composition that may experience worse outcomes or would benefit from preoperative intervention is of clinical interest. Traditional body composition analysis methods are resource intensive; therefore, linear segmentation with routine imaging has been proposed as a clinically practical alternative. This study assesses linear segmentation’ ...
Tópico(s): Colorectal Cancer Surgical Treatments
2022 - Frontiers Media | Frontiers in Oncology
John H. Powers, M. Lourdes Guerrero, Nancy Kline Leidy, Mary Fairchok, Alice Rosenberg, Andrés Hernández, Sonja Stringer, Christina Schofield, Patricia Rodríguez‐Zulueta, Katherine Kim, Patrick J. Danaher, Hilda Ortega-Gallegos, Elizabeth D. Bacci, Nathaniel Stepp, Arturo Galindo‐Fraga, Kristina St. Clair, Michael Rajnik, Erin A. McDonough, Michelande Ridoré, John Arnold, Eugene V. Millar, Guillermo M. Ruiz‐Palacios,
To develop content validity of a comprehensive patient-reported outcome (PRO) measure following current best scientific methodology to standardize assessment of influenza (flu) symptoms in clinical research. Stage I (Concept Elicitation): 1:1 telephone interviews with influenza-positive adults (≥18 years) in the US and Mexico within 7 days of diagnosis. Participants described symptom type, character, severity, and duration. Content analysis identified themes and developed the draft Flu-PRO instrument. ...
Tópico(s): Delphi Technique in Research
2015 - BioMed Central | BMC Infectious Diseases
Benjamin N. Schmeusser, Eric Midenberg, Arnold R. Palacios, Adil Ali, Dattatraya Patil, Michelle Higgins, Reza Nabavizadeh, Benjamin Croll, Milton Williams, J. E. SHEEHY, Bill Zheng, Vikram M. Narayan, Shreyas Joshi, Kenneth Ogan, Sarah P. Psutka, Mehmet Asım Bilen, Viraj A. Master,
Tópico(s): Peripheral Artery Disease Management
2023 - Elsevier BV | Clinical Genitourinary Cancer
Benjamin N. Schmeusser, Arnold R. Palacios, Eric Midenberg, Reza Nabavizadeh, Adil Ali, Dattatraya Patil, R. Donald Harvey, Janetta Bryksin, Michael Connor, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
... PATIENTS WITH RENAL CELL CARCINOMA Benjamin N. Schmeusser, Arnold R. Palacios, Eric Midenberg, Reza Nabavizadeh, Adil Ali, Dattatraya H. ... Benjamin N. Schmeusser More articles by this author Arnold R. Palacios More articles by this author Eric Midenberg More ...
Tópico(s): Renal Diseases and Glomerulopathies
2023 - Lippincott Williams & Wilkins | The Journal of Urology
Eric R. Midenberg, Benjamin N. Schmeusser, Arnold R. Palacios, Kristin E. Larsen, Dattatraya Patil, Ben Petrinec, Ben Croll, Thien‐Linh Le, Gordon Hong, Fangyi Rose Lin, Kaleena Jesson, Grace Lee, Frances Y. Kwon, Kenneth Ogan, Viraj A. Master,
Quantifying grit with the Short Grit Scale (Grit-S) has shown ability to predict success in various academic and professional domains. Grit has yet to be analyzed in patients with cancer.This study is a longitudinal analysis of prospectively distributed Grit-S surveys to patients undergoing radical or partial nephrectomy. Patients who completed a preoperative Grit-S survey with confirmed renal cell carcinoma (RCC) were included in the analysis. The relationship between preoperative grit scores and ...
Tópico(s): Optimism, Hope, and Well-being
2022 - AME Publishing Company | Translational Andrology and Urology
Marcela Henríquez‐Henríquez, Maria T. Acosta, Ariel F. Martinez, Jorge I. Vélez, Francisco Lopera, David Pineda, Juan David Palacio, Teresa Quiroga, Tilla S. Worgall, Richard J. Deckelbaum, Claudio A. Mastronardi, Brooke S. G. Molina, Benedetto Vitiello, Joanne B. Severe, Peter S. Jensen, L. Eugene Arnold, Kimberly Hoagwood, John E. Richters, Donald Vereen, Stephen P. Hinshaw, Glen R. Elliott, Karen C. Wells, Jeffery N. Epstein, Desiree W. Murray, C. Keith Conners, John S. March, James M. Swanson, Timothy Wigal, Dennis P. Cantwell, Howard Abikoff, Lily Hechtman, Laurence L. Greenhill, Jeffrey H. Newcorn, Brooke S. G. Molina, Betsy Hoza, William E. Pelham, Robert D. Gibbons, Sue M. Marcus, Kwan Hur, Helena C. Kraemer, Thomas Hanley, Karen Stern, Mauricio Arcos‐Burgos, Maximilian Muenke,
Attention deficit hyperactivity disorder (ADHD) is the most prevalent neurodevelopmental disorder in children, with genetic factors accounting for 75-80% of the phenotypic variance. Recent studies have suggested that ADHD patients might present with atypical central myelination that can persist into adulthood. Given the essential role of sphingolipids in myelin formation and maintenance, we explored genetic variation in sphingolipid metabolism genes for association with ADHD risk. Whole-exome genotyping ...
Tópico(s): Lysosomal Storage Disorders Research
2020 - Springer Nature | Translational Psychiatry
Catherine Arnold, Jonathan C. Guito, Louis A. Altamura, Sean Lovett, Elyse R. Nagle, Gustavo Palacios, Mariano Sánchez-Lockhart, Jonathan S. Towner,
The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral responses. This dynamic would contrast with humans, where MARV-mediated interferon (IFN) antagonism early in infection is thought to contribute to the severe, often fatal disease. The newly-annotated ERB genome and transcriptome have now enabled us to use a ...
Tópico(s): Viral gastroenteritis research and epidemiology
2018 - Multidisciplinary Digital Publishing Institute | Viruses
Joseph Prescott, Jonathan C. Guito, Jessica R. Spengler, Catherine Arnold, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Lisa Wiggleton Guerrero, Gustavo Palacios, Mariano Sánchez-Lockhart, César G. Albariño, Jonathan S. Towner,
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents without overt disease, while permitting sufficient replication to allow for transmission and maintenance in a population, is important for understanding the viral ecology and spillover to humans. The Egyptian rousette bat (ERB) has been identified ...
Tópico(s): Hepatitis B Virus Studies
2019 - American Society for Microbiology | mSphere
Edouard Nicaise, Benjamin N. Schmeusser, Adil Ali, Eric Midenberg, Arnold R. Palacios, Blaise Hartsoe, Ethan Kearns, Sriram Ambadi, Dattatraya Patil, Shreyas Joshi, Vikram M. Narayan, Sarah P. Psutka, Bassel Nazha, Jacqueline T. Brown, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
Abstract Introduction Baseline sarcopenia and postoperative changes in muscle mass are independently associated with overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) undergoing cytoreductive nephrectomy (CN). Here we examine the relationships between preoperative (baseline), postoperative changes in muscle quantity, and survival outcomes following CN as determined by linear segmentation, a clinic-friendly tool that rapidly estimates muscle mass. Materials & Methods Our nephrectomy ...
Tópico(s): Advanced X-ray and CT Imaging
2024 - Elsevier BV | Clinical Genitourinary Cancer
Edouard Nicaise, Benjamin N. Schmeusser, Adil Ali, Eric Midenberg, Arnold R. Palacios, Ethan Kearns, Sriram Ambadi, Dattatraya Patil, Shreyas Joshi, Vikram M. Narayan, Sarah P. Psutka, Bassel Nazha, Jacqueline T. Brown, Kenneth Ogan, Mehmet Asım Bilen, Viraj A. Master,
380 Background: Baseline sarcopenia and postoperative changes in muscle mass are independently associated with overall survival in patients with metastatic renal cell carcinoma (mRCC) undergoing cytoreductive nephrectomy (CN). Here we examine the relationship between preoperative (baseline) and postoperative changes in muscle quantity with survival outcomes following CN as determined by linear segmentation, a fast and clinic-friendly tool. Methods: Our nephrectomy database was reviewed for patients ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... the 2018 election, sixty-fiveyear-old Lieutenant Governor Arnold I Palacios, told reporters that he and Saipan's Republican ...
Tópico(s): Geology and Paleoclimatology Research
2023 - University of Hawaii Press | The Contemporary Pacific/The contemporary Pacific (Online)
... Governor Torres and his running mate, Senate President Arnold I Palacios. The administration had "accomplished a lot and… made ...
Tópico(s): Climate Change, Adaptation, Migration
2020 - University of Hawaii Press | The Contemporary Pacific/The contemporary Pacific (Online)
Alexandrea Arnold, J. A. Mering, Lenin D. Chari, Cristian Román‐Palacios, Huashu Li, hyn Victoria Petrys, Bryce Mitsunaga, Ben Elliott, John Wilson, Jamie Lucarelli, Ronny Boch, Daniel Ibarra, Lin Li, Majie Fan, Darrell S. Kaufman, Andrew S. Cohen, Robert B. Dunbar, James M. Russell, Stefan V. Lalonde, Priyadarsi D. Roy, Martin Dietzel, Xingqi Liu, Fengming Chang, Robert A. Eagle, Aradhna Tripati,
Abstract Lacustrine, riverine and spring carbonates represent archives of terrestrial climates and their geochemistry has been used to study palaeoenvironments. Clumped isotope thermometry is an emerging tool that has been applied to freshwater carbonates. Limited work has been done to evaluate comparative relationships between clumped isotopes and temperature in different types of modern freshwater carbonates. This study assembles an extensive calibration data set with 135 samples of modern freshwater ...
Tópico(s): Hydrocarbon exploration and reservoir analysis
2024 - Wiley | The Depositional Record
Michael Hamacher, Katrin Marcus, Christoph Stephan, Joachim Klose, Young Mok Park, Helmut E. Meyer,
... Scopus (31) Google Scholar, 4Hamacher M. Apweiler R. Arnold G. Becker A. Bluggel M. Carrette O. Colvis C. Dunn M.J. Frohlich T. Fountoulakis M. van Hall A. Herberg F. Ji J. Kretzschmar H. Lewczuk P. Lubec G. Marcus K. Martens L. Palacios Bustamante N. Park Y.M. Pennington S.R. ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2008 - Elsevier BV | Molecular & Cellular Proteomics
Benjamin N. Schmeusser, Adil Ali, Dattatraya Patil, Arnold R. Palacios, Manuel Armas‐Phan, Kenneth Ogan, Viraj A. Master,
616 Background: Accurate prediction of future glomerular function rate (fGFR) following nephrectomy in renal cell carcinoma (RCC) patients is of interest. A postoperative estimated glomerular filtration (eGFR) rate ≥ 45 mL/min/1.73m2 is considered favorable, with guidelines reflecting these findings. Though nephron sparing surgery is preferable, radical nephrectomy is often the preferred oncologic surgery. Various models to predict postoperative renal function have been proposed, with a new 2021 equation ...
Tópico(s): Renal and Vascular Pathologies
2023 - Lippincott Williams & Wilkins | Journal of Clinical Oncology