Timo T. Myöhänen, J. Arturo García‐Horsman, Jofre Tenorio‐Laranga, Pekka T. Männistö,
Prolyl oligopeptidase (POP) is a serine endopeptidase that hydrolyses proline-containing peptides shorter than 30 amino acids. POP may be associated with cognitive functions, possibly via the cleavage of neuropeptides. Recent studies have also suggested novel non-hydrolytic and non-catalytic functions for POP. Moreover, POP has also been proposed as a regulator of inositol 1,4,5-triphosphate signaling and several other functions such as cell proliferation and differentiation, as well as signal transduction ...
Tópico(s): Signaling Pathways in Disease
2009 - SAGE Publishing | Journal of Histochemistry & Cytochemistry
Mirva J. Hannula, Timo T. Myöhänen, J. Tenorio-Laranga, Pekka T. Männistö, J. Arturo García‐Horsman,
Prolyl oligopeptidase (EC 3.4.21.26, PREP) is a serine protease that hydrolyzes proline-containing peptides shorter than 30-mer but it has also nonhydrolytic functions. PREP has been shown to accelerate aggregation of wild-type α-synuclein (α-syn) under cell-free conditions, and PREP inhibitors can block this aggregation both in vitro and in vivo. α-syn is the main component of Lewy bodies in Parkinson's disease (PD) and Lewy body dementia. To clarify the possible interaction of PREP with other markers ...
Tópico(s): Adenosine and Purinergic Signaling
2013 - Elsevier BV | Neuroscience
Jofre Tenorio‐Laranga, Pekka T. Männistö, J. Arturo García‐Horsman,
Prolyl oligopeptidase (POP) is a serine protease that cleaves peptides shorter than 30-mer at the carboxyl side of an internal proline. POP has been proposed to be involved in some pathologies including mood disorders and neurodegenerative diseases. However, the physiological role of POP remains unknown. To validate POP as a drug target, it is essential to obtain a thorough understanding of its function in vivo. Identification of physiological substrates and products of POP is an important step towards ...
Tópico(s): Signaling Pathways in Disease
2011 - Bentham Science Publishers | CNS & Neurological Disorders - Drug Targets
Jofre Tenorio‐Laranga, Jarkko I. Venäläinen, Pekka T. Männistö, J. Arturo García‐Horsman,
Prolyl oligopeptidase (POP) is a serine protease that cleaves small peptides at the carboxyl side of an internal proline residue. Substance P, arginine-vasopressin, thyroliberin and gonadoliberin are proposed physiological substrates of this protease. POP has been implicated in a variety of brain processes, including learning, memory, and mood regulation, as well as in pathologies such as neurodegeneration, hypertension, and psychiatric disorders. Although POP has been considered to be a soluble ...
Tópico(s): Signaling Pathways in Disease
2008 - Wiley | FEBS Journal
Anne Penttinen, Jofre Tenorio‐Laranga, Anssi Siikanen, Markus Morawski, Steffen Roßner, J. Arturo García‐Horsman,
Inhibitors of prolyl oligopeptidase have been reported to be neuroprotective, especially in memory loss caused by lesion or disease. This enzyme has also been implicated in neurodegeneration. Although it was initially thought that prolyl oligopeptidase functioned to directly control of neuropeptide levels, emerging evidence points out in part that this peptidase modulates peptides which in turn regulate inflammatory responses. Here we review the recent literature which indicates a direct involvement ...
Tópico(s): Ubiquitin and proteasome pathways
2011 - Bentham Science Publishers | CNS & Neurological Disorders - Drug Targets
M.J. Moreno-Baylach, Katja A. Puttonen, Jofre Tenorio‐Laranga, Jarkko I. Venäläinen, Markus Storvik, Markus Forsberg, J. Arturo García‐Horsman,
Prolyl endopeptidase (PREP), probably acting through the inositol cycle, has been implicated in memory and learning. However, the physiological role of PREP is unknown. It has been shown that PREP expression, regulated in cerebellar granule cells, has probably a role in cell proliferation and differentiation. Here, we report the levels and subcellular distribution of PREP in human neuroblastoma SH-SY5Y cells in proliferating conditions and under differentiation induced by retinoic acid (RA). We analysed ...
Tópico(s): Neuropeptides and Animal Physiology
2011 - Karger Publishers | Neurosignals
Jofre Tenorio‐Laranga, Pekka T. Männistö, Maria Karayiorgou, Joseph A. Gogos, J. Arturo García‐Horsman,
Catechol-O-methyl transferase (COMT) methylates catechols, such as l-dopa and dopamine, and COMT deficient mice show dramatic shifts in the metabolite levels of catechols. Increase in catechol metabolite levels can, in principle, lead to oxidative stress but no indices of oxidative stress have been reported in COMT-knockout (KO) mice [Forsberg MM, Juvonen RO, Helisalmi P, Leppanen J, Gogos JA, Karayiorgou M, et al. Lack of increased oxidative stress in catechol-O-methyltransferase (COMT)-deficient mice. ...
Tópico(s): Mitochondrial Function and Pathology
2009 - Elsevier BV | Biochemical Pharmacology
Jofre Tenorio‐Laranga, F Coret-Ferrer, Buenaventura Casanova-Estruch, María Burgal, J. Arturo García‐Horsman,
Abstract Background Multiple sclerosis (MS) is a complex, inflammatory and neurodegenerative disease of the central nervous system leading to long-term disability. Recent studies indicate a close association between inflammation and neurodegeneration in all lesions and disease stages of MS. Prolyl oligopeptidase (POP) is a proline-specific serine protease that cleaves several neuroactive peptides. This peptidase has been implicated in neurodegeneration, as well as in the modulation of the inflammatory ...
Tópico(s): Neuropeptides and Animal Physiology
2010 - BioMed Central | Journal of Neuroinflammation
Timo T. Myöhänen, J. Tenorio-Laranga, Birgitta Jokinen, R Vázquez‐Sánchez, M.J. Moreno-Baylach, J. Arturo García‐Horsman, Pekka T. Männistö,
BACKGROUND AND PURPOSE A serine protease, prolyl oligopeptidase (POP) has been reported to be involved in the release of the pro-angiogenic tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Ac-SDKP) from its precursor, 43-mer thymosin β4 (Tβ4). Recently, it was shown that both POP activity and the levels of Ac-SDKP are increased in malignant tumours. The aim of this study was to clarify the release of Ac-SDKP, and test if POP and a POP inhibitor, 4-phenyl-butanoyl-L-prolyl-2(S)-cyanopyrrolidine (KYP-2047), can ...
Tópico(s): Neuropeptides and Animal Physiology
2010 - Wiley | British Journal of Pharmacology
Jofre Tenorio‐Laranga, Pekka T. Männistö, Markus Storvik, Pieter Van der Veken, J. Arturo García‐Horsman,
Prolyl oligopeptidase (PREP) cleaves short peptides at the C-side of proline. Although several proline containing neuropeptides have been shown to be efficiently cleaved by PREP in vitro, the actual physiological substrates of this peptidase are still a matter of controversy. The aim of this study was to evaluate the changes in the peptidome of rat tissues caused by a repeated 4-day administration of the potent and specific PREP inhibitor KYP-2047, using our recently developed iTRAQ-based technique. ...
Tópico(s): Signaling Pathways in Disease
2012 - Elsevier BV | Biochimie
Jofre Tenorio‐Laranga, Carmina Montoliú, Amparo Urios, Vicente Hernández‐Rabaza, Hanan Ahabrach, J. Arturo García‐Horsman, Vicente Felipo,
Liver failure in experimental animals or in human cirrhosis elicits neuroinflammation. Prolyl oligopeptidase (PREP) has been implicated in neuroinflammatory events in neurodegenerative diseases: PREP protein levels are increased in brain glial cells upon neuroinflammatory insults, but the circulating PREP activity levels are decreased in multiple sclerosis patients in a process probably mediated by bioactive peptides. In this work, we studied the variation of PREP levels upon liver failure and correlated ...
Tópico(s): Neuropeptides and Animal Physiology
2015 - BioMed Central | Journal of Neuroinflammation
Jofre Tenorio‐Laranga, M. Luz Valero, Pekka T. Männistö, Manuel M. Sánchez del Pino, J. Arturo García‐Horsman,
In vitro, prolyl oligopeptidase (POP) cleaves proline-containing bioactive peptides such as substance P, gonadotropin-releasing hormone, thyrotropin-releasing hormone, arginine-vasopressin, and neurotensin. Based on specific in vivo inhibition, POP has been suggested to be involved in cognitive and psychiatric processes but the identity of its physiological substrates has remained inconclusive. We have combined (a) sample snap-freezing and boiling buffer extraction, to limit protein degradation and ...
Tópico(s): Signaling Pathways in Disease
2009 - Elsevier BV | Analytical Biochemistry
Hugo G. Castelán‐Sánchez, Paola Elorrieta, Pedro Romoacca, Arturo Liñan-Torres, José Luis Sierra-Monzón, Ingrid Vera, Ramón Alberto Batista‐García, Silvia Tenorio‐Salgado, Gabriel Lizama‐Uc, Ernesto Pérez‐Rueda, María Antonieta Quispe-Ricalde, Sonia Dávila‐Ramos,
Intermediate-salinity environments are distributed around the world. Here, we present a snapshot characterization of two Peruvian thalassohaline environments at high altitude, Maras and Acos, which provide an excellent opportunity to increase our understanding of these ecosystems. The main goal of this study was to assess the structure and functional diversity of the communities of microorganisms in an intermediate-salinity environment, and we used a metagenomic shotgun approach for this analysis. ...
Tópico(s): Bacteriophages and microbial interactions
2019 - Multidisciplinary Digital Publishing Institute | Genes
Nancy Labastida-Mercado, Samantha Galindo-Becerra, Mónica Patricia González-Ramírez, Karla Miravete-Lagunes, Andrés Gómez‐De‐León, Sergio Ponce‐de‐León, Andrea P. Tenorio-Rojo, Nora Ángela Martagón-Herrera, Jesús Hernández-Reyes, Arturo García-Villaseñor, Esteban Burguette-Hernandez, Guillermo J Ruiz Delgado, David Gómez‐Almaguer, Guillermo J. Ruíz‐Argüelles,
Quality of life (QOL) is an important consideration in the counseling, implementation, and post treatment management of arduous treatments for life-threatening conditions, such as allogeneic hematopoietic cell transplantation (allo-HCT). QOL was analyzed in leukemia patients who underwent allo-HCT using reduced intensity conditioning (RIC) on an outpatient basis at either the Centro de Hematología y Medicina Interna de Puebla of the Clínica Ruiz or the Hematology Service of the Internal Medicine Department ...
Tópico(s): Cancer survivorship and care
2015 - Elsevier BV | Biology of Blood and Marrow Transplantation
Jofre Tenorio‐Laranga, Iida Peltonen, Salla Keskitalo, Gilberto Duran-Torres, Renuka Natarajan, Pekka T. Männistö, Antti Nurmi, Nina Vartiainen, Laura Airas, Irina Elovaara, J. Arturo García‐Horsman,
Prolyl oligopeptidase (PREP) has been considered as a drug target for the treatment of neurodegenerative diseases. In plasma, PREP has been found altered in several disorders of the central nervous system including multiple sclerosis (MS). Oxidative stress and the levels of an endogenous plasma PREP inhibitor have been proposed to decrease PREP activity in MS. In this work, we measured the circulating levels of PREP in patients suffering of relapsing remitting (RR), secondary progressive (SP), primary ...
Tópico(s): Cell Adhesion Molecules Research
2013 - Elsevier BV | Biochemical Pharmacology
Jossue Ortíz-Álvarez, Arturo Becerra, Alfonso Méndez-Tenorio, Jazmín Murcia-Garzón, Lourdes Villa‐Tanaca, García Hernández,
Abstract Cytochrome P450s from the CYP52 family participate in the assimilation of alkanes and fatty acids in fungi. In this work, the evolutionary history of a set of orthologous and paralogous CYP52 proteins from Saccharomycetales yeasts was inferred. Further, the phenotypic assimilation profiles were related with the distribution of cytochrome CYP52 members among species. The maximum likelihood phylogeny of CYP52 inferred proteins reveled a frequent ancient and modern duplication and loss events ...
Tópico(s): Microbial Natural Products and Biosynthesis
2020 - Nature Portfolio | Scientific Reports
Emilio Bouza, Maricela Valerio, Álex Soriano, Laura Morata, Enrique García Carús, Carmen Rodríguez, Carmen Hidalgo‐Tenorio, Antonio Pláta Ciézar, Patricia Muñóz, Antonio Vena, Ana Álvarez‐Uría, Ana Fernández‐Cruz, Ascensión Arroyo Nieto, Arturo Artero, José María Barbero Allende, Enrique Bernal, Francisco Javier Candel, Laura Castelo, Javier Cobo, Maria del Carmen Gálvez Contreras, R. Güerri Fernández, Juan Pablo Horcajada, Pablo Guisado‐Vasco, Juan Emilio Losa, Rafael Hervás, Simona Iftimie, Jiménez-Mejías Me, Francisco Jover, José Luis Lamas Ferreiro, Ana B. Serrano, Eduardo Malmierca, Mar Masiá, María Rosa Oltra Sempere, Alicia Rico, Dolors Rodríguez-Pardo, Sergio J. Rodriguez Alvarez, Rafael San Juan, Cristina Sarriá Cepeda, María Antonia Sepúlveda Berrocal, Beatriz Sobrino, Luisa Sorlí,
Dalbavancin is a lipoglycopeptide with a very prolonged half-life enabling treatment with a single intravenous administration that has been approved to treat complicated skin and soft-tissue infections. Information on the efficacy and safety of dalbavancin in other situations is very scarce. This retrospective study included adult patients who received at least one dose of dalbavancin between 2016 and 2017 in 29 institutions in Spain. The primary objective was to report the use of dalbavancin in ...
Tópico(s): Streptococcal Infections and Treatments
2017 - Elsevier BV | International Journal of Antimicrobial Agents
Jaime Mondragón-Ancelmo, Patricia García-Hernández, Luis Alejandro Ojas-Sandoval, Ignacio Arturo Domínguez Vara, Germán Gómez-Tenorio, Samuel Rebollar Rebollar,
Se caracterizó a los consumidores agroindustriales (CAI) de pequeños rumiantes para carne (PRC) en el Estado de México. Con una encuesta semiestructurada se obtuvo información sociodemográfica, de comercialización e importancia de los atributos de los PRC (peso vivo, sexo, raza, entre otros). Los datos se analizaron con la técnica de componentes principales, prueba de Tukey y Kruskal-Wallis. De acuerdo con su similitud entre objetos (73.3% de la varianza total y KMO= 0.802), se obtuvieron tres grupos ...
Tópico(s): Logistics and Transportation Systems
2018 - | Investigación y Ciencia de la Universidad Autónoma de Aguascalientes
Mirva J. Hannula, Timo T. Myöhänen, J. Tenorio-Laranga, Pekka T. Männistö, J. Arturo García‐Horsman,
The authors regret to report a minor error in the figure 4 legend on page 145. The authors incorrectly stated the color magenta for PREP and the color green for β-amyloid in the fluorescent photomicrographs. The correct text should read, “Representative fluorescent photomicrographs illustrating a colocalization of PREP (green) and β-amyloid (magenta) in Alzheimer’s disease (AD) and control human hippocampus (HC) and entorhinal cortex.” Prolyl oligopeptidase colocalizes with α-synuclein, β-amyloid, tau ...
Tópico(s): Peptidase Inhibition and Analysis
2013 - Elsevier BV | Neuroscience
Arturo Pabel Miranda-Aguirre, Sergio Hernández-García, Juan Alberto Tenorio-Torres, Miguel Arnoldo Farias-Alarcón, Solís Aura Erazo-Valle,
Los tumores neuroendocrinos (NET) son neoplasias poco comunes, pero con una tasa de inci dencia cada vez mas alta en el mundo. El objetivo de este estudio es describir la experiencia del Centro Medico Nacional “20 de noviembre” en el manejo de pacientes con NET. Material y metodo: Se realizo un estudio de tipo retrospectivo, transversal, observacional y descriptivo, en pacientes con diagnostico de NET atendidos en el Servicio de Oncologia quirurgica del Centro Medico Nacional “20 de noviembre”, de ...
Tópico(s): Neuroblastoma Research and Treatments
2012 - Elsevier BV | Gaceta Mexicana de Oncología
Jofre Tenorio‐Laranga, M. Luz Valero, Pekka T. Männistö, Manuel M. Sánchez del Pino, J. Arturo García‐Horsman,
Tópico(s): Glycosylation and Glycoproteins Research
2009 - Elsevier BV | Analytical Biochemistry
Irma Berenice Mulato-Briones, Ismael Olan Rodríguez-Ildefonso, Julián Antonio Jiménez-Tenorio, Patricia Isidra Cauich-Sánchez, María del Socorro Méndez-Tovar, Gerardo Aparicio‐Ozores, María Yicel Bautista-Hernández, Juan Francisco González-Parra, Jesús Cruz-Hernández, Ricardo López-Romero, Teresita María del Rosario Rojas-Sánchez, Raúl García-Palacios, Ónix Garay-Villar, Teresa Apresa-García, Juan López-Esparza, Daniel Marrero‐Rodríguez, Juan Arturo Castelán-Vega, Alicia Jiménez-Alberto, Mauricio Salcedo, Rosa María Ribas‐Aparicio,
Traditional microbiological methodology is valuable and essential for microbiota composition description and microbe role assignations at different anatomical sites, including cervical and vaginal tissues; that, combined with molecular biology strategies and modern identification approaches, could give a better perspective of the microbiome under different circumstances. This pilot work aimed to describe the differences in microbiota composition in non-cancer women and women with cervical cancer ...
Tópico(s): Cervical Cancer and HPV Research
2024 - Multidisciplinary Digital Publishing Institute | Cancers
Circe Gómez-Tenorio, Virgilia Soto‐Abraham, Carmen Díaz-Leal C, Juan A. García-Bello, Karen V. Ordaz-López, Norma E. Guerra-Hernández, Miguel Arturo Márquez-Gutierrez, Sergio Franco-Ornelas,
Las enfermedades por depósito lisosomal son un grupo heterogéneo de unos 50 trastornos metabólicos hereditarios.Estos trastornos tienen en común un déficit genético de enzimas u otras proteínas relacionadas con la hidrólisis de macromoléculas en los lisosomas. Salvo tres, que se heredan ligadas al cromosoma X, las demás tienen un patrón de herencia autosómico recesivo. Se clasifican por el tipo de sustrato que se acumula en los lisosomas.Por su prevalencia, se las considera enfermedades raras, aunque ...
Tópico(s): Trypanosoma species research and implications
2016 - Elsevier BV | Molecular Genetics and Metabolism
Rodrigo Guerrero, Pedro Rovetto,
... Pedro Pablo Scarpetta, Agustín Escobar, Enrique Garcés, Adolfo Tenorio, and Pablo García Aguilera, among others. The need to create a ...
Tópico(s): Health and Medical Education
2010 - University of Valle | Colombia medica
Isabel Zegrí‐Reiriz, Arístides de Alarcón, Patricia Muñóz, Manuel Martínez‐Sellés, Víctor José González Ramallo, José M. Miró, Carlos Falces, Claudia Gonzalez‐Rico, Xabier Kortajarena Urkola, José Antonio Lepe, Regino Rodríguez, José María Reguera Iglesias, Enrique Navas, Fernándo Domínguez, Pablo García‐Pavía, Fernando Fernández Sánchez, Mariam Noureddine, Gabriel Rosas, Javier de la Torre, José I. Aramendi, Elena Bereciartúa, Marı́a José Blanco, Roberto Blanco, María Victoria Boado, Marta Campaña Lázaro, Alejandro Crespo, Josune Goikoetxea, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Javier Nieto, David Rodrigo, David Rodríguez, Regino Rodríguez, Yolanda Vitoria, Roberto Voces, María Victoria García López, Radka Ivanova Georgieva, Guillermo Ojeda, Isabel Rodríguez Bailón, Josefa Ruíz Morales, Ana María Cuende, Tomás Echeverría, Ana Fuerte, Eduardo Gaminde, Miguel Ángel Goenaga, Pedro Idígoras, José Antonio Iribarren, Alberto Izaguirre Yarza, Xabier Kortajarena Urkola, Carlos Reviejo, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Nemesio Álvarez, José María Bravo-Ferrer, Laura Castelo, José J. Cuenca‐Castillo, Pedro Llinares, Enrique Míguez Rey, María Rodríguez Mayo, Efrén Sánchez, Dolores Sousa, F.J. Martínez-Moreno, M.M. Alonso, Beatriz Castro, Dácil García Rosado, Ma del Carmen Durán, Ma Antonia Miguel Gómez, Juan Lacalzada‐Almeida, Ibrahim Nassar, Antonio Pláta Ciézar, José Ma Reguera Iglesias, Víctor Asensi, Carlos Costas, Jesús de la Hera, Jonathan Fernández-Suárez, Lisardo Iglesias Fraile, Víctor León, José López Menéndez, Pilar Mencía Bajo, Carlos Morales, Alfonso Moreno Torrico, Carmen Palomo, B. Martínez, Ángeles Rodríguez Esteban, Raquel Rodríguez-García, Mauricio Telenti Asensio, Manuel Almela, Juan Ambrosioni, Manuel Azqueta, Merçè Brunet, Marta Bodro, Ramón Cartañá, Carlos Falces, Guillermina Fita, David Fuster, Cristina García de la Mària, Marta Hernández‐Meneses, Jaume Llopis Pérez, Francesc Marco, José M. Miró, Asunción Moreno, David Nicolás, Salvador Pié i Ninot, Eduard Quintana, Carlos Paré, Daniel Pereda, Juan M. Pericàs, José Luís Pomar, J. M. Ramírez, Irene Rovira, Elena Sandoval, Marta Sitges, Dolors Soy, Adrián Téllez, José M Tolosana, Bárbara Vidal, Jordi Vilà, Iván Adán, Javier Bermejo, Emilio Bouza, Daniel Celemín, Gregorio Cuerpo Caballero, Antonia Delgado-Montero, Ana Fernández‐Cruz, Ana García Mansilla, María Eugenia García Leoni, Víctor José González Ramallo, Martha Kestler Hernández, Amaia Marí Hualde, Mercedes Marín, Manuel Martínez‐Sellés, María Cruz Menárguez, Patricia Muñóz, Cristina Rincón, Hugo Rodríguez-Abella, Marta Rodríguez‐Créixems, Blanca Pinilla, Ángel Pinto, Maricela Valerio, Pilar Vázquez, Eduardo Verde Moreno, Isabel Antorrena, Belén Loeches, Alejandro Martín‐Quirós, Mar Moreno, Ulises Ramírez, Verónica Rial Bastón, María Pilar Romero‐Gómez, Araceli Saldaña, Jesús Agüero Balbín, Carlos Armiñanzas Castillo, Ana Arnáiz, Francisco Arnaíz de las Revillas, Manuel Cobo Belaustegui, María Carmen Fariñas, Concepción Fariñas-Álvarez, Rubén Gómez Izquierdo, Iván García, Claudia Gonzalez‐Rico, Manuel Gutiérrez‐Cuadra, José Gutiérrez Díez, Marcos Pajarón, José Antonio Parra, Ramón Teira, Jesús Zarauza, Fernándo Domínguez, Pablo García‐Pavía, Jesús G. Mirelis, Beatriz Orden, António Ramos, Marta Cobo Marcos, Tomasa Centella, José Manuel Hermida, José Luis Betrán Moya, Pilar Martín‐Dávila, Enrique Navas, Enrique Oliva, Alejandro del Río, Soledad Ruíz, Carmen Hidalgo‐Tenorio, Manuel Almendro Delia, Omar Araji, José Miguel Barquero, Román Calvo Jambrina, Marina de Cueto, Juan Gálvez-Acebal, Irene Méndez, Isabel Morales, Luis Eduardo López-Cortés, Arístides de Alarcón, Emilio García, Juan Luis Haro, José Antonio Lepe, Francisco López, Rafael Luque, Luis Javier Alonso, Pedro Azcárate, José Manuel Azcona, José Ramón Blanco, Lara García-Álvarez, José A. Oteo, Mercedes Sanz, Natividad Benito, Mercè Gurguí, Cristina Pacho, R. Pericás, Guillem Pons, Ángel L. Fernández, Amparo Martínez, Arturo Prieto, Benito Regueiro, Marino Vega, Andrés Canut Blasco, José Cordo Mollar, Juan Carlos Gainzarain Arana, Oscar García Uriarte, Alejandro Martín López, Zuriñe Ortiz de Zárate, José Antonio Urturi Matos, Fernándo Domínguez, Antonio Sánchez-Porto, José María Arribas, Elisa García Vázquez, Alicia Hernández Torres, Ana Lozano-Blázquez, Gonzalo de la Morena, Ángel Cabo Alonso, Javier Aramburu, Felicitas Elena Calvo, Anai Moreno Rodríguez, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, José Largo Pau, María Antonia Sepúlveda, Pilar Toledano Sierra, Sadaf Zafar Iqbal-Mirza, Eva Cascales Alcolea, Pilar Egea Serrano, Jose Roca, I. Keituqwa Yáñez, Ana Peláez Ballesta, Víctor Soriano, Eduardo Moreno Escobar, Alejandro Peña Monje, Valme Sánchez Cabrera, David Vinuesa García, María Arrizabalaga Asenjo, Carmen Luna, Juana Núñez Morcillo, Ma Cruz Pérez Seco, Aroa Villoslada Gelabert, Carmen Aured Guallar, Nuria Fernández Abad, Pilar García Mangas, Marta Matamala Adell, Ma Pilar Palacián Ruiz, Juan Carlos Porres, Begoña Alcaraz Vidal, Nazaret Cobos Trigueros, María Jesús Del Amor Espín, José Antonio Giner, Roberto Jiménez Sánchez, Amaya Jimeno Almazán, Alejandro Ortín Freire, Monserrat Viqueira González, Pere Pericás Ramis, Ma Ángels Ribas Blanco, Enrique Ruiz de Gopegui Bordes, Laura Vidal Bonet, Ma Carmen Bellón Munera, Elena Escribano Garaizábal, Antonia Tercero Martínez, Juan Carlos Segura Luque,
There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions. This study sought to describe the clinical and microbiological features of IE in patients with BAV and MVP and compare them with those of IE patients with and without IEAP indication, to determine the potential benefit of IEAP in these conditions. This analysis involved 3,208 ...
Elsevier BV | Journal of the American College of Cardiology
José Manuel Casas Rojo, Juan Miguel Antón Santos, Jesús Millán-Núñez-Cortés, Ricardo Gómez‐Huelgas, José Manuel Ramos, Manuel Rubio‐Rivas, Miguel-Ángel Corrales-González, Maria-Rosa Fernández-Madera-Martínez, José-Luis Beato-Pérez, Francisco Arnalich, Cristina Gallego‐Lezaún, Pablo Pérez‐Martínez, Sonia Molinos‐Castro, Yale Tung‐Chen, Manuel Madrazo, Manuel Méndez‐Bailón, Daniel Monge-Monge, Gema-María García-García, Rosa García Fenoll, N Gilabert, Rebeca Fuerte-Martínez, Marta Contreras-Sánchez, Nicolás Rhyman, Jorge Peris-García, Carlos Lumbreras, Ana Belén Barbero-Barrera, Blanca Beamonte-Vela, Coralia Bueno, Charo Burón-Fernández, Ruth Calderón-Hernáiz, Irene Casado-López, José Manuel Casas Rojo, Andrés Cortés-Troncoso, Pilar Cubo‐Romano, F Déodati, Alejandro Estrada-Santiago, Gonzalo García-Casasola Sánchez, Elena García Guijarro, Francisco Javier García Sánchez, Pilar García de la Torre, Mayte de Guzmán García-Monge, Davide Luordo, María Mateos González, José Antonio Melero-Bermejo, Cruz Pastor-Valverde, José Luis Pérez-Quero, Fernando Roque-Rojas, Lorea Roteta-García, Elena Sierra-Gonzalo, Francisco Javier Teigell-Muñoz, Juan Vicente de la Sota, Javier Villanueva-Martínez, Laura Abarca Casas, Álvaro Alejandre de Oña, Rubén Alonso Beato, Leyre Alonso Gonzalo, Jaime Alonso Muñoz, Crhistian‐Mario Oblitas, Cristina Ausín García, Marta Bacete Cebrián, Jesús Baltasar Corral, María Barrientos Guerrero, Alejandro David Bendala Estrada, María Calderón Moreno, Paula Carrascosa Fernández, Raquel Carrillo, Sabela Castañeda Pérez, Eva Cervilla Muñoz, Agustín Diego Chacón Moreno, Maria Carmen Cuenca Carvajal, Sergio De los Santos, Andrés Enríquez Gómez, Eduardo Fernández Carracedo, María Mercedes Ferreiro-Mazón Jenaro, Francisco Galeano Valle, Alejandra García‐García, Irene Garcia Fernandez-Bravo, María Eugenia García Leoni, María Gómez Antúnez, Candela González San Narciso, Anthony Alexander Gurjian, Lorena Jiménez Ibáñez, Cristina Lavilla Olleros, Cristina Llamazares Mendo, Sara L. Garcia, Víctor Mato Jimeno, Clara Millán Nohales, Jesús Millán Núñez-Cortés, Sergio Moragón Ledesma, Antonio Muiño Míguez, Cecilia Muñoz Delgado, Lucía Ordieres Ortega, Susana Pardo Sánchez, Alejandro Parra Virto, María Teresa Pérez Sanz, Blanca Pinilla Llorente, Sandra Piqueras Ruiz, Guillermo Soria Fernández‐Llamazares, María Toledano Macías, Neera Toledo Samaniego, Ana Torres do Rego, María Victoria Villalba García, Gracia Villarreal, María Zurita Etayo, Ma Mar Ayala-Gutiérrez, Rosa Bernal López, José Bueno Fonseca, Verónica Andrea Buonaiuto, Luis Francisco Caballero Martínez, Lidia Cobos-Palacios, Clara Costo Muriel, Francis de Windt, Ana Teresa Fernandez-Truchaud Christophel, Paula García Ocaña, Ricardo Gómez‐Huelgas, Javier Gorospe García, José Antonio Hurtado Oliver, Sergio Jansen‐Chaparro, Maria D. López‐Carmona, Pablo López Quirantes, Almudena López‐Sampalo, Elizabeth Lorenzo-Hernández, Juan José Mancebo Sevilla, Jesica Martín Carmona, Luis Miguel Pérez-Belmonte, Iván Pérez de Pedro, Araceli Pineda-Cantero, Carlos Romero Gómez, Michele Ricci, Jaime Sanz Cánovas, José Manuel Ramos, Xavier Corbella, Francesc Formiga Pérez, Narcı́s Homs, Abelardo Montero, José María Mora‐Luján, Manuel Rubio‐Rivas, Victoria Augustín Bandera, Javier García Alegría, Nicolás Jiménez-García, Jairo Luque del Pino, María Dolores Martín Escalante, Francisco Navarro Romero, Victoria Rodríguez, Julián Olalla, Ana María Álvarez Suárez, Carlos Delgado Vergés, Rosa Fernández-Madera Martínez, Eva Ma Fonseca Aizpuru, Alejandro Gómez Carrasco, Cristina Helguera Amezua, Juan Francisco López Caleya, Diego López Martínez, María del Mar Martínez López, Aleida Martínez Zapico, Carmen Olabuenaga Iscar, Lucía Pérez Casado, María Luisa Taboada Martínez, Lara María Tamargo Chamorro, José Luis Beato Pérez, Maria Lourdes Sáez Méndez, Jorge Álvarez Troncoso, Francisco Arnalich, Francisco Blanco Quintana, Carmen Busca, Sergio Carrasco Molina, Aránzazu Castellano Candalija, Germán Daroca Bengoa, Alejandro de Gea Grela, Alicia de Lorenzo Hernández, Alejandro Vidal, Carmen Fernández Capitán, Maria Francisca García Iglesias, Borja González Muñoz, Carmen Rosario Herrero Gil, Juan María Herrero‐Martínez, Víctor Hontañón, M.J. Jaras, Carlos Lahoz, Cristina Marcelo, Juan Carlos Martín Gutiérrez, Monica Martinez Prieto, Elena Martínez Robles, Araceli Saldaña, Alberto Moreno Fernández, José M. Prieto, Ana Noblejas Mozo, Carlos Manuel Oñoro López, Esmeralda Palmier Peláez, Marina Palomar Pampyn, María Angustias Quesada Simón, Juan Carlos Ramos Ramos, Luis Ramos Ruperto, Aquilino Sánchez Purificación, Teresa Sancho Bueso, Raquel Sorriguieta Torre, Clara Itziar Soto Abanedes, Yeray Untoria Tabares, Marta Varas Mayoral, Julia Vásquez Manau, Nicolás Alcalá Rivera, Anxela Crestelo Vieitez, Esther del Corral Beamonte, Jesús Díez‐Manglano, Isabel Fiteni Mera, María del Mar García Andreu, Martín Gericó Aseguinolaza, Cristina Gállego Lezaún, Claudia Josa‐Laorden, Raúl Martínez Murgui, Marta Teresa Matía Sanz, Antonio P. Arenas-de Larriva, Pilar Calero Espinal, Javier Delgado‐Lista, Francisco Fuentes, María del Carmen Guerrero Martínez, María Jesús Gómez Vázquez, Jose Jiménez Torres, Laura Limia Pérez, José López‐Miranda, Laura Martín Piedra, Marta Millán Orge, Javier Pascual Vinagre, Pablo Pérez‐Martínez, María Elena Revelles Vílchez, Ángela Rodrigo Martínez, Juan Luis Romero Cabrera, José D. Torres‐Peña, Maria del Carmen Beceiro Abad, María Aurora Freire Romero, Sonia Castro, Emilio Páez-Guillán, María Pazo Nuñez, Paula María Pesqueira Fontán, Ane Andrés Eisenhofer, Ana Arias Milla, Isolina Baños Pérez, Laura Benítez Gutiérrez, Javier Bilbao Garay, Jorge Calderón‐Parra, Alejandro Callejas Díaz, Erika Camacho Da Silva, MaCruz Carreño Hernández, Raquel Díaz, María Jesús Citores Sánchez, Carmen Cubero Gozalo, Valentín Cuervas-Mons Martínez, Laura Dorado Doblado, Sara de la Fuente Moral, Alberto Díaz de Santiago, Itziar Diego Yagüe, Ignacio Donate Velasco, Ana Duca, Pedro Durán del Campo, Gabriela Escudero López, Esther Expósito Palomo, Ana Fernández‐Cruz, Amy Galán Gómez, Sonia García, Beatriz García Revilla, Miguel Ángel García Viejo, Javier Gómez Irusta, Patricia González Merino, Edith Vanessa Gutiérrez Abreu, Isabel Gutiérrez, Ángela Gutiérrez Rojas, Andrea Gutiérrez Villanueva, Jesús Herráiz Jiménez, Fátima Ibáñez Estéllez, P. Laguna del Estal, Ma Carmen Máinez Saíz, Carmen de Mendoza Fernández, María Martínez Urbistondo, Fernando Martínez Vera, María Mateos Seirul-lo, Susana Mellor Pita, Patricia A. Mills Sánchez, Esther Montero Hernández, Alberto Mora Vargas, Víctor Moreno‐Torres, Ignacio Morrás De La Torre, Elena Múñez, Rosa Muñoz de Benito, Patricia Muñóz, Pablo Navarro Palomo, Ilduara Pintos Pascual, Arturo José Ramos Martín-Vegue, António Ramos, Celia Rodríguez Olleros, Alberto Roldán Montaud, Yolanda Romero Pizarro, Silvia Rosado García, Diana Ruiz de Domingo, David Sánchez Ortiz, Enrique Sánchez Chica, Irene Solano Almena,
Abstract In 2020, the COVID-19 pandemic followed a two-wave pattern in most countries. Hospital admission for COVID-19 in one wave or another could have affected mortality, especially among the older persons. The objective of this study was to evaluate whether the admission of older patients during the different waves, before SARS-CoV-2 vaccination was available, was associated with a different mortality. We compared the mortality rates of patients hospitalized during 2020 before (first wave) and ...
Nature Portfolio
José Manuel Ramos, Paula Sol Ventura, José-Manuel Casas-Rojo, Marc Mauri, Carlos Lumbreras, Aitor Ortiz de Latierro, Manuel Rubio‐Rivas, Luis Mérida-Rodrigo, Lucía Pérez-Casado, María Barrientos-Guerrero, V. Giner, Cristina Gallego‐Lezaún, Almudena Hernández Milian, Luís Manzano, Julio César Blázquez-Encinar, Marta Nataya Solís Marquínez, Marcos Guzmán García, Julia Lobo‐García, Victoria Achával-Rodríguez Valente, Celia Roig‐Martí, Marta León-Téllez, Pablo Tellería-Gómez, María Jesús González-Juárez, Ricardo Gómez‐Huelgas, Alejandro López‐Escobar, José Manuel Ramos, Carlos Lumbreras, Jesús Millán Núñez-Cortés, Juan Miguel Antón Santos, Ricardo Gómez‐Huelgas, Xavier Corbella, Francesc Formiga Pérez, Narcı́s Homs, Abelardo Montero, José María Mora‐Luján, Manuel Rubio‐Rivas, Victoria Augustín Bandera, Javier García Alegría, Nicolás Jiménez-García, Jairo Luque del Pino, María Dolores Martín Escalante, Francisco Navarro Romero, Victoria Rodríguez, Julián Olalla, Paloma Agudo de Blas, Coral Arévalo Cañas, Blanca Ayuso, José Bascuñana Morejón, Samara Campos Escudero, María Carnevali Frías, Santiago Cossio Tejido, Borja de Miguel Campo, Carmen Díaz Pedroche, Raquel Diaz Simón, Ana García Reyne, Laura Ibarra Veganzones, Lucía de Jorge Huerta, Antonio Lalueza Blanco, Jaime Laureiro Gonzalo, Jaime Lora-Tamayo, Carlos Lumbreras, Guillermo Maestro de la Calle, Rodrigo Miranda Godoy, Barbara Otero Perpiña, Diana Paredes-Ruíz, Marcos Sánchez Fernández, Javier Tejada Montes, Ana María Álvarez Suárez, Carlos Delgado Vergés, Rosa Fernández-Madera Martínez, Eva Ma Fonseca Aizpuru, Alejandro Gómez Carrasco, Cristina Helguera Amezua, Juan Francisco López Caleya, Diego López Martínez, María del Mar Martínez López, Aleida Martínez Zapico, Carmen Olabuenaga Iscar, Lucía Pérez Casado, María Luisa Taboada Martínez, Lara María Tamargo Chamorro, Laura Abarca Casas, Álvaro Alejandre de Oña, Rubén Alonso Beato, Leyre Alonso Gonzalo, Jaime Alonso Muñoz, Crhistian‐Mario Oblitas, Cristina Ausín García, Marta Bacete Cebrián, Jesús Baltasar Corral, María Barrientos Guerrero, Alejandro David Bendala Estrada, María Calderón Moreno, Paula Carrascosa Fernández, Raquel Carrillo, Sabela Castañeda Pérez, Eva Cervilla Muñoz, Agustín Diego Chacón Moreno, Maria Carmen Cuenca Carvajal, Sergio De los Santos, Andrés Enríquez Gómez, Eduardo Fernández Carracedo, María Mercedes Ferreiro-Mazón Jenaro, Francisco Galeano Valle, Alejandra García‐García, Irene Garcia Fernandez-Bravo, María Eugenia García Leoni, María Gómez Antúnez, Candela González San Narciso, Anthony Alexander Gurjian, Lorena Jiménez Ibáñez, Cristina Lavilla Olleros, Cristina Llamazares Mendo, Sara L. Garcia, Víctor Mato Jimeno, Clara Millán Nohales, Jesús Millán Núñez-Cortés, Sergio Moragón Ledesma, Antonio Muiño Míguez, Cecilia Muñoz Delgado, Lucía Ordieres Ortega, Susana Pardo Sánchez, Alejandro Parra Virto, María Teresa Pérez Sanz, Blanca Pinilla Llorente, Sandra Piqueras Ruiz, Guillermo Soria Fernández‐Llamazares, María Toledano Macías, Neera Toledo Samaniego, Ana Torres do Rego, María Victoria Villalba García, Gracia Villarreal, María Zurita Etayo, Rafael Aragón Lara, Inmaculada Cimadevilla Fernandez, Juan Carlos Cira García, Gema María García García, Julia Gonzalez Granados, Beatriz Guerrero Sánchez, Francisco Javier Monreal Periáñez, Maria Josefa Pascual Perez, José Luis Beato Pérez, Maria Lourdes Sáez Méndez, Nicolás Alcalá Rivera, Anxela Crestelo Vieitez, Esther del Corral Beamonte, Jesús Díez‐Manglano, Isabel Fiteni Mera, María del Mar García Andreu, Martín Gericó Aseguinolaza, Cristina Gállego Lezaún, Claudia Josa‐Laorden, Raúl Martínez Murgui, Marta Teresa Matía Sanz, Ma Mar Ayala-Gutiérrez, Rosa Bernal López, José Bueno Fonseca, Verónica Andrea Buonaiuto, Luis Francisco Caballero Martínez, Lidia Cobos-Palacios, Clara Costo Muriel, Francis de Windt, Ana Teresa Fernandez-Truchaud Christophel, Paula García Ocaña, Ricardo Gómez‐Huelgas, Javier Gorospe García, José Antonio Hurtado Oliver, Sergio Jansen‐Chaparro, Maria D. López‐Carmona, Pablo López Quirantes, Almudena López‐Sampalo, Elizabeth Lorenzo-Hernández, Juan José Mancebo Sevilla, Jesica Martín Carmona, Luis M. Pérez‐Belmonte, Iván Pérez de Pedro, Araceli Pineda-Cantero, Carlos Romero Gómez, Michele Ricci, Jaime Sanz Cánovas, Jorge Álvarez Troncoso, Francisco Arnalich, Francisco Blanco Quintana, Carmen Busca, Sergio Carrasco Molina, Aránzazu Castellano Candalija, Germán Daroca Bengoa, Alejandro de Gea Grela, Alicia de Lorenzo Hernández, Alejandro Vidal, Carmen Fernández Capitán, Maria Francisca García Iglesias, Borja González Muñoz, Carmen Rosario Herrero Gil, Juan María Herrero‐Martínez, Víctor Hontañón, M.J. Jaras, Carlos Lahoz, Cristina Marcelo, Juan Carlos Martín Gutiérrez, Monica Martinez Prieto, Elena Martínez Robles, Araceli Saldaña, Alberto Moreno Fernández, José M. Prieto, Ana Noblejas Mozo, Carlos Manuel Oñoro López, Esmeralda Palmier Peláez, Marina Palomar Pampyn, María Angustias Quesada Simón, Juan Carlos Ramos Ramos, Luis Ramos Ruperto, Aquilino Sánchez Purificación, Teresa Sancho Bueso, Raquel Sorriguieta Torre, Clara Itziar Soto Abanedes, Yeray Untoria Tabares, Marta Varas Mayoral, Julia Vásquez Manau, Maria del Carmen Beceiro Abad, María Aurora Freire Romero, Sonia Molinos Castro, Emilio Páez-Guillán, María Pazo Nuñez, Paula María Pesqueira Fontán, Antonio P. Arenas-de Larriva, Pilar Calero Espinal, Javier Delgado‐Lista, Francisco Fuentes, María del Carmen Guerrero Martínez, María Jesús Gómez Vázquez, Jose Jiménez Torres, Laura Limia Pérez, José López‐Miranda, Laura Martín Piedra, Marta Millán Orge, Javier Pascual Vinagre, Pablo Pérez‐Martínez, María Elena Revelles Vílchez, Ángela Rodrigo Martínez, Juan Luis Romero Cabrera, José D. Torres‐Peña, Marisa Asensio Tomás, David Baláž, David Bonet Tur, Ruth Cañizares Navarro, Paloma Chazarra Pérez, Jesús Corbacho Redondo, Eliana Damonte White, María Escamilla Espínola, Leticia Espinosa del Barrio, Pedro Jesús Esteve Atiénzar, Carles García Cervera, David Francisco García Núñez, Francisco Garrido Navarro, V. Giner, Angie Gómez Uranga, Javier Guzmán Martínez, Isidro Hernández Isasi, Lourdes Lajara Villar, Verónica Martínez Sempere, Juan Manuel Núñez Cruz, Sergio Palacios Fernández, Juan Jorge Peris García, Rafael Piñol Pleguezuelos, Andrea Riaño Pérez, José Miguel Seguí Ripoll, Azucena Sempere Mira, Philip Wikman-Jorgensen, Juan Ayllón, Arturo Artero, María del Mar Carmona Martín, María José Fabiá Valls, Maria de Mar Fernández Garcés, A Belda, Ian López Cruz, Manuel Madrazo López, Elisabeth Mateo Sanchis, Jaume Micó Gandia, Laura Piles Roger, Adela Maria Pina Belmonte, Alba Viana García, Ane Andrés Eisenhofer, Ana Arias Milla, Isolina Baños Pérez, Laura Benítez Gutiérrez, Javier Bilbao Garay, Jorge Calderón‐Parra, Alejandro Callejas Díaz, Erika Camacho Da Silva, MaCruz Carreño Hernández, Raquel Castejón Díaz, María Jesús Citores Sánchez, Carmen Cubero Gozalo, Valentín Cuervas-Mons Martínez, Laura Dorado Doblado,
Springer Science+Business Media
Carlos Montanā, Rodolfo Dirzo, Arturo Flores,
... Ramirez, A. Salinas, J. Sanchez-ken, and P. Tenorio 1993. Listados florísticos de México. X. Flora del Valle de Tehuacán-Cuicatlán. Instituto de Biología, Universidad Nacional Autónoma de México, México . Garcia, E. 1973. Modificaciones al sistema de clasificación climática ...
Tópico(s): Plant and animal studies
1997 - Wiley | Biotropica
Crhistian‐Mario Oblitas, Pablo Demelo-Rodríguez, Lucía Barrera-López, Francisco Galeano‐Valle, Manuel Rubio‐Rivas, Jairo Luque del Pino, V. Giner, Diana Paredes-Ruíz, Rosa Fernández-Madera Martínez, Martín Gericó Aseguinolaza, Ricardo Gómez‐Huelgas, Francisco Arnalich Fernández, José D. Torres‐Peña, José I. González, Manuel Méndez‐Bailón, Daniel Monge Monge, Santiago J. Freire Castro, Cruz Pastor Valverde, Enrique Rodilla, Marcos Guzmán García, María Rivas-Carmenado, César Gallo-Salazar, Marina Amparo Perea Ribis, José Manuel Casas Rojo, Jesús Millán Núñez-Cortés, Xavier Corbella, Francesc Formiga Pérez, Narcı́s Homs, Abelardo Montero, José María Mora‐Luján, Manuel Rubio‐Rivas, Victoria Augustín Bandera, Javier García Alegría, Nicolás Jiménez-García, Jairo Luque del Pino, María Dolores Martín Escalante, Francisco Navarro Romero, Victoria Rodríguez, Julián Olalla, Marisa Asensio Tomás, David Baláž, David Bonet Tur, Ruth Cañizares Navarro, Paloma Chazarra Pérez, Jesús Corbacho Redondo, Eliana Damonte White, María Escamilla Espínola, Leticia Espinosa del Barrio, Pedro Jesús Esteve Atiénzar, Carles García Cervera, David Francisco García Núñez, Francisco Garrido Navarro, V. Giner, Angie Gómez Uranga, Javier Guzmán Martínez, Isidro Hernández Isasi, Lourdes Lajara Villar, Verónica Martínez Sempere, Juan Manuel Núñez Cruz, Sergio Palacios Fernández, Juan Jorge Peris García, Rafael Piñol Pleguezuelos, Andrea Riaño Pérez, José Miguel Seguí Ripoll, Azucena Sempere Mira, Philip Wikman-Jorgensen, Paloma Agudo de Blas, Coral Arévalo Cañas, Blanca Ayuso García, José Bascuñana Morejón, Samara Campos Escudero, María Carnevali Frías, Santiago Cossio Tejido, Borja de Miguel Campo, Carmen Díaz Pedroche, Raquel Diaz Simón, Ana García Reyne, Laura Ibarra Veganzones, Lucía de Jorge Huerta, Antonio Lalueza Blanco, Jaime Laureiro Gonzalo, Jaime Lora‐Tamayo, Carlos Lumbreras, Guillermo Maestro de la Calle, Rodrigo Miranda Godoy, Barbara Otero Perpiña, Diana Paredes-Ruíz, Marcos Sánchez Fernández, Javier Tejada Montes, Ana María Álvarez Suárez, Carlos Delgado Vergés, Rosa Fernández-Madera Martínez, Eva Ma Fonseca Aizpuru, Alejandro Gómez Carrasco, Cristina Helguera Amezua, Juan Francisco López Caleya, Diego López Martínez, María del Mar Martínez López, Aleida Martínez Zapico, Carmen Olabuenaga Iscar, Lucía Pérez Casado, María Luisa Taboada Martínez, Lara María Tamargo Chamorro, Laura Abarca Casas, Álvaro Alejandre de Oña, Rubén Alonso Beato, Leyre Alonso Gonzalo, Jaime Alonso Muñoz, Crhistian‐Mario Oblitas, Cristina Ausín García, Marta Bacete Cebrián, Jesús Baltasar Corral, María Barrientos Guerrero, Alejandro David Bendala Estrada, María Calderón Moreno, Paula Carrascosa Fernández, Raquel Carrillo, Sabela Castañeda Pérez, Eva Cervilla Muñoz, Agustín Diego Chacón Moreno, Maria Carmen Cuenca Carvajal, Sergio De los Santos, Andrés Enríquez Gómez, Eduardo Fernández Carracedo, María Mercedes Ferreiro-Mazón Jenaro, Francisco Galeano Valle, Alejandra García‐García, Irene Garcia Fernandez-Bravo, María Eugenia García Leoni, María Gómez Antúnez, Candela González San Narciso, Anthony Alexander Gurjian, Lorena Jiménez Ibáñez, Cristina Lavilla Olleros, Cristina Llamazares Mendo, Sara L. Garcia, Víctor Mato Jimeno, Clara Millán Nohales, Jesús Millán Núñez-Cortés, Sergio Moragón Ledesma, Antonio Muiño Míguez, Cecilia Muñoz Delgado, Lucía Ordieres Ortega, Susana Pardo Sánchez, Alejandro Parra Virto, María Teresa Pérez Sanz, Blanca Pinilla Llorente, Sandra Piqueras Ruiz, Guillermo Soria Fernández‐Llamazares, María Toledano Macías, Neera Toledo Samaniego, Ana Torres do Rego, María Victoria Villalba García, Gracia Villarreal, María Zurita Etayo, Rafael Aragón Lara, Inmaculada Cimadevilla Fernandez, Juan Carlos Cira García, Gema María García García, Julia Gonzalez Granados, Beatriz Guerrero Sánchez, Francisco Javier Monreal Periáñez, Maria Josefa Pascual Perez, José Luis Beato Pérez, Maria Lourdes Sáez Méndez, Nicolás Alcalá Rivera, Anxela Crestelo Vieitez, Esther del Corral Beamonte, Jesús Díez‐Manglano, Isabel Fiteni Mera, María del Mar García Andreu, Martín Gericó Aseguinolaza, Cristina Gállego Lezaún, Claudia Josa‐Laorden, Raúl Martínez Murgui, Marta Teresa Matía Sanz, Ma Mar Ayala-Gutiérrez, Rosa Bernal López, José Bueno Fonseca, Verónica Andrea Buonaiuto, Luis Francisco Caballero Martínez, Lidia Cobos-Palacios, Clara Costo Muriel, Francis de Windt, Ana Teresa Fernandez-Truchaud Christophel, Paula García Ocaña, Ricardo Gómez‐Huelgas, Javier Gorospe García, José Antonio Hurtado Oliver, Sergio Jansen‐Chaparro, Maria D. López‐Carmona, Pablo López Quirantes, Almudena López‐Sampalo, Elizabeth Lorenzo-Hernández, Juan José Mancebo Sevilla, Jesica Martín Carmona, Luis Miguel Pérez-Belmonte, Iván Pérez de Pedro, Araceli Pineda-Cantero, Carlos Romero Gómez, Michele Ricci, Jaime Sanz Cánovas, Jorge Álvarez Troncoso, Francisco Arnalich Fernández, Francisco Blanco Quintana, Carmen Busca, Sergio Carrasco Molina, Aránzazu Castellano Candalija, Germán Daroca Bengoa, Alejandro de Gea Grela, Alicia de Lorenzo Hernández, Alejandro Vidal, Carmen Fernández Capitán, Maria Francisca García Iglesias, Borja González Muñoz, Carmen Rosario Herrero Gil, Juan María Herrero‐Martínez, Víctor Hontañón, M.J. Jaras, Carlos Lahoz, Cristina Marcelo, Juan Carlos Martín Gutiérrez, Monica Martinez Prieto, Elena Martínez Robles, Araceli Saldaña, Alberto Moreno Fernández, José M. Prieto, Ana Noblejas Mozo, Carlos Manuel Oñoro López, Esmeralda Palmier Peláez, Marina Palomar Pampyn, María Angustias Quesada Simón, Juan Carlos Ramos Ramos, Luis Ramos Ruperto, Aquilino Sánchez Purificación, Teresa Sancho Bueso, Raquel Sorriguieta Torre, Clara Itziar Soto Abanedes, Yeray Untoria Tabares, Marta Varas Mayoral, Julia Vásquez Manau, Maria del Carmen Beceiro Abad, María Aurora Freire Romero, Sonia Castro, Emilio Páez-Guillán, María Pazo Nuñez, Paula María Pesqueira Fontán, Antonio P. Arenas-de Larriva, Pilar Calero Espinal, Javier Delgado‐Lista, Francisco Fuentes, María del Carmen Guerrero Martínez, María Jesús Gómez Vázquez, Jose Jiménez Torres, Laura Limia Pérez, José López‐Miranda, Laura Martín Piedra, Marta Millán Orge, Javier Pascual Vinagre, Pablo Pérez‐Martínez, María Elena Revelles Vílchez, Ángela Rodrigo Martínez, Juan Luis Romero Cabrera, José D. Torres‐Peña, Gloria María Alonso Claudio, Víctor Barreales Rodríguez, Cristina Muñoz, Adela Carpio Pérez, María Victoria Coral Orbes, Daniel Encinas Sánchez, Sandra Inés Revuelta, Miguel Marcos, José I. González, José-Ángel Martín-Oterino, Leticia Moralejo Alonso, Sonia Peña Balbuena, María Luisa Pérez García, Ana Ramon Prados, Beatriz Rodríguez‐Alonso, Ángela Romero Alegría, María Sánchez Ledesma, Rosa Juana Tejera Pérez, Juan Ayllón, Arturo Artero, María del Mar Carmona Martín, María José Fabiá Valls, Maria de Mar Fernández Garcés, A Belda, Ian López Cruz, Manuel Madrazo, Elisabeth Mateo Sanchis, Jaume Micó Gandia, Laura Piles Roger, Adela Maria Pina Belmonte, Alba Viana García, Ane Andrés Eisenhofer,
Nature Portfolio
Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman, Joelle Mbatchou, Michael P. Turner, Sheila M. Gaynor, Tyler Joseph, Yuxin Zou, Daren Liu, Rachel Wade, Jeffrey Staples, Razvan Panea, Alex Popov, Xiaodong Bai, Suganthi Balasubramanian, Lukas Habegger, Rouel Lanche, Alex Lopez, Evan K. Maxwell, Marcus B. Jones, Humberto Garcia‐Ortíz, Raúl Ramírez-Reyes, Rogelio Santacruz-Benítez, Abhishek Nag, Katherine R. Smith, Amy Damask, Nan Lin, Charles Paulding, Mark Reppell, Sebastian Zöllner, Eric Jorgenson, William Salerno, Slavé Petrovski, John D. Overton, Jeffrey G. Reid, Timothy A. Thornton, Gonçalo R. Abecasis, Jaime Berúmen, Lorena Orozco, Rory Collins, Gonçalo R. Abecasis, Adolfo A. Ferrando, Michael Cantor, Giovanni Coppola, Andrew Deubler, Aris N. Economides, Katia Karalis, Luca A. Lotta, Lyndon J. Mitnaul, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Katherine Siminovitch, Christina Beechert, Erin D. Brian, Laura M. Cremona, Hang Du, Caitlin Forsythe, Zhenhua Gu, Kristy Guevara, Michael Lattari, Alexander Lopez, Kia Manoochehri, Manasi Pradhan, Raymond Reynoso, Ricardo Schiavo, Maria Sotiropoulos Padilla, Chenggu Wang, Sarah E. Wolf, Amelia Averitt, Nilanjana Banerjee, Dadong Li, Sameer Malhotra, Justin Mower, Mudasar Sarwar, Deepika Sharma, Jeffrey Staples, Jay Sundaram, Sean Yu, Aaron Zhang, Mona Nafde, George Mitra, Sujit Gokhale, Andrew Bunyea, Janice Clauer, Krishna Pawan Punuru, Sanjay Sreeram, Gisu Eom, Benjamin Sultan, Vrushali Mahajan, Eliot Austin, Koteswararao Makkena, Sean O’Keeffe, Tommy Polanco, Ayesha Rasool, William Salerno, Lance Zhang, Boris Boutkov, Evan Edelstein, Alexander Gorovits, Ju Guan, Alicia Hawes, Olga Krasheninina, Adam J. Mansfield, Evan K. Maxwell, Suying Bao, Kathie Sun, Chuanyi Zhang, Manuel Allen Revez Ferreira, Kathy Burch, Adrián I. Campos, Lei Chen, Sam Choi, Liron Ganel, Sheila M. Gaynor, Benjamin Geraghty, Akropravo Ghosh, Salvador Romero Martinez, Christopher E. Gillies, Lauren Gurski, Joseph Herman, Michael D. Kessler, Jack A. Kosmicki, Adam E. Locke, Priyanka Nakka, Anthony Marcketta, Arden Moscati, Aditeya Pandey, Anita Pandit, Jonathan Ross, Carlo Sidore, Eli A. Stahl, Maria Suciu, Peter VandeHaar, Sailaja Vedantam, Scott Vrieze, Rujin Wang, Kuan-Han Wu, Bin Ye, Blair Zhang, Olivier Delaneau, Maya Ghoussaini, Jingning Zhang, Brian D. Hobbs, Jon Silver, William Palmer, Rita Guerreiro, Jan Freudenberg, Amit D. Joshi, Antoine Baldassari, Cristen J. Willer, Sarah E. Graham, Jonas B. Nielsen, Mary Hass, Niek Verweij, George Hindy, Jonas Bovijn, Tanima De, Parsa Akbari, Luanluan Sun, Olukayode Sosina, Arthur Gilly, Peter Dornbos, Juan L. Rodriguez‐Flores, Moeen Riaz, Manav Kapoor, Gannie Tzoneva, Momodou W. Jallow, Anna Alkelai, Ariane Ayer, Veera M. Rajagopal, Sahar Gelfman, Vijay Kumar, Jacqueline M. Otto, Neel Parikshak, Ayşegül Güvenek, José Brás, Silvia Álvarez, Jessie Brown, Jin He, Hossein Khiabanian, Marcus B. Jones, Esteban Chen, Jaimee Hernandez, Michelle G. LeBlanc, Jason Mighty, Nirupama Nishtala, Nadia Rana, Jennifer Rico‐Varela, Jonathan Emberson, Richard Peto, Abraham Garduño-Martinez, A. García-López, Adrian Abarca-Cardoso, Adriana Caballero-Mondragon, Adriana Gutierrez-Parra, Adriana Leticia Diaz-Avila, Alan Emiliano Bautista-Hernandez, Alberto Méndez-Villalba, Aldo Shaid Ramos-Hernandez, Alejandra Alejo-Salazar, Alejandra Angelica Perez-Moncada, Alejandra Martinez, Alejandra Peralta-Gallardo, Alejandro Flores-Magana, Alfa Izamar Benitez-Garcia, Alicia González-Castillo, Alicia Villegas-Esparza, Alma Delia Morales-Bravo, Alma Fernanda Mora-Negrete, Alma Hernandez-Galicia, Alma Rosa Arenas-García, Alma Rosa Valentin-Martinez, Amalia Paredes-Rojas, Ambar Nayeli Flores-Sanchez, Amelia Ortiz-Jaen, America Juarez-Salazar, América Victoria Cervantes-Torres, Amparo Luviano-Martínez, Ana del Carmen Alejandro-Perez, Ana Dominguez-Alvarado, Ana Isabel Fuentes-Alvarado, Ana Karen Arreola-Olvera, Ana Laura Bautista-Sanchez, Ana Lilia Enríquez-Álvarez, Ana Lilia Reynoso-Valverde, Ana María Isidro-Cid, Ana Montserrat Lechuga-Mendoza, Andrea Esquivel-Mejía, Andrea Galvino-Antonio, Andrea Gomez-Luna, Andres Martinez-Martinez, Anel Aragón-Domínguez, Angelica Gamboa-Romero, Angélica Hernández Guerrero, Angelica Ruiz-Hernandez, Antonia González-María, Araceli Martínez-Santana, Araceli Rojas-Vásquez, Arcelia Rojas-Santamaría, Armida Sánchez-Corral, Athzin Berenice Rosas-Avila, Beatriz Cruz-Acevedo, Beatriz Gonzalez-Ibañes, Beatriz Rojas, Beatriz Velázquez-Mancilla, Belen Escalona-Franco, Bernardo Ochoa-Morales, Braulio Rivera-Cortés, Brenda Castañeda-Gazpar, Brenda J. Calderon-Garcia, Brenda Jimena Jimenez-Gutierrez, Brian Orlando Sanchez-Martin, Carlos Alberto Toxqui-Rico, Carlos Antonio Clemente-Montano, Carlos Daniel Jimenez-Gutierrez, Casandra Alvarez-Meneses, Catalina Gasca-Velázquez, Cecilia Luna-Barroso, César Marín-Pérez, Cinthia Calderon-Camacho, Cinthia Hernandez-Perez, Cinthia Xóchitl Hernández-Peralta, Clarinet Castillo-Rioja, Claudia Bustamante-Durán, Claudia Elizabeth Espinosa-Quintana, Claudia Lilia Galicia-Flores, Claudia Lizbeth Villagomez-Piña, Cynthya Berenice Sierra-Martinez, Daniel Fernández-Corona, Daniel Ordaz-Jiménez, Daniela Oreli Hernandez-Castillo, Daniela Ramirez-Aranda, Dante Zazhil Lopez-Guzman, Diana del Monte-Homobono, Diana Isabel Gonzalez-Enciso, Diana Laura Bolanos-Hernandez, Edith Elizabeth Valdez-Solano, Edith Gonzalez-Torres, Edson Alfonso Mercado-Hernández, Eduardo Alvarado-Valle, Elisa Morales-Martinez, Elizabet Gonzalez, Elsa Yadira Díaz-Martínez, Elvia Isabel Vázquez-Torres, Elvira Ramos-Mendoza, Emiliano del Rio-Gonzalez, Erika Alpizar-Flores, Erika García-García, Erika Pérez-Romero, Esmeralda Sanchez-Martinez, Estefania Perez-Perez, Estela Beatriz López-García, Estela Elisabeth Moran-De Los Santos, Esther Jerónimo-Hernández,
The Mexico City Prospective Study is a prospective cohort of more than 150,000 adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in Mexico City
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