Anthony Harries, P Gomani, Roger Teck, Olga Ascurra de Teck, E Bakali, Rony Zachariah, Edwin Libamba, Andrina Mwansambo, Felix Salaniponi, Rex Mpazanje,
... author on: Oxford Academic PubMed Google Scholar Olga Ascurra de Teck, Olga Ascurra de Teck bMedicins sans Frontieres-Luxembourg, Thyolo District, ...
Tópico(s): HIV Research and Treatment
2004 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Leila Meyer, Karin Esemann‐Quadros, Ana Lúcia Bertarello Zeni,
... Serra do Itajai National Park, Atlantic Forest area, Ascurra city, Santa Catarina state, Brazil. Fourty-two inhabitants ...
Tópico(s): Phytochemistry and Bioactivity Studies
2012 - UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL | Revista Brasileira de Biociências
Yerisf C. Torres Ascurra, Lisha Zhang, AmirAli Toghani, Chenlei Hua, Nandeesh Jalahalli Rangegowda, Andrés Posbeyikian, Hsuan Pai, Xiao Lin, Pieter J. Wolters, Doret Wouters, R. de Blok, Niels Steigenga, M.J.M. Paillart, Richard G. F. Visser, Sophien Kamoun, Thorsten Nürnberger, Vivianne G. A. A. Vleeshouwers,
Plant cell surface pattern recognition receptors (PRRs) and intracellular immune receptors cooperate to provide immunity to microbial infection. Both receptor families have coevolved at an accelerated rate, but the evolution and diversification of PRRs is poorly understood. We have isolated potato surface receptor Pep-13 receptor unit (PERU) that senses Pep-13, a conserved immunogenic peptide pattern from plant pathogenic
Tópico(s): Legume Nitrogen Fixing Symbiosis
2023 - American Association for the Advancement of Science | Science
Produção Nacional
Iêda M. Orioli, Helen Dolk, Jorge S. López‐Camelo, Boris Groisman, Adriana Benavides‐Lara, Lucas G. Giménez, Daniel Mattos, Marta Ascurra, Eliana de Aquino Bonilha, Maria Aurora Canessa‐Tapia, Giovanny Vinícius Araújo de França, Paula Hurtado‐Villa, Marisol Ibarra‐Ramírez, Rosa Pardo, Dania Maria Pastora, Ignacio Zarante, Flávia Mahatma Schneider Soares, Flávia Martinez de Carvalho, Mariana Piola,
Abstract The early detection of congenital anomaly epidemics occurs when comparing current with previous frequencies in the same population. The success of epidemiologic surveillance depends on numerous factors, including the accuracy of the rates available in the base period, wide population coverage, and short periodicity of analysis. This study aims to describe the Latin American network of congenital malformation surveillance: ReLAMC, created to increase epidemiologic surveillance in Latin America. ...
Tópico(s): Child Nutrition and Water Access
2020 - Wiley | American Journal of Medical Genetics Part C Seminars in Medical Genetics
Produção Nacional
Revisado por pares
Ana Carolina Brusius‐Facchin, Ida Vanessa Döederlein Schwartz, Constantin Zimmer, Márcia Gonçalves Ribeiro, Angelina Xavier Acosta, Dafne Dain Gandelman Horovitz, Isabella Lopes Monlleó, Marshall Ítalo Barros Fontes, Agnes Cristina Fett‐Conte, Ruy P. Oliveira Sobrinho, Andréa R. Duarte, Raquel Boy, Paulina Mabe, Marta Ascurra, Maria De Michelena, Karen Tylee, G. T. N. Besley, M.C.V. Garreton, Roberto Giugliani, Sandra Leistner‐Segal,
In this study, 103 unrelated South-American patients with mucopolysaccharidosis type II (MPS II) were investigated aiming at the identification of iduronate-2-sulfatase (IDS) disease causing mutations and the possibility of some insights on the genotype–phenotype correlation The strategy used for genotyping involved the identification of the previously reported inversion/disruption of the IDS gene by PCR and screening for other mutations by PCR/SSCP. The exons with altered mobility on SSCP were sequenced, ...
Tópico(s): Glycogen Storage Diseases and Myoclonus
2013 - Elsevier BV | Molecular Genetics and Metabolism
Simon D Makombe, Edwin Libamba, Eustice Mhango, Olga de Ascurra Teck, John Aberle‐Grasse, Mindy Hochgesang, Erik J Schouten, Anthony Harries,
Malawi is scaling-up provision of free antiretroviral therapy (ART) in the public sector. In the fourth quarter of 2004 and the first quarter of 2005, 3261 and 4530 new patients, respectively, were started on ART. Of these patients, approximately 40% were male and 95% were adults aged > or =13 years. The age group data show that women who accessed ART were in general 10 years younger than men. Between 84% and 90% of patients were started on ART because of being clinically assessed as being in WHO stages ...
Tópico(s): HIV/AIDS drug development and treatment
2006 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Edwin Libamba, Simon D Makombe, Eustice Mhango, Olga de Ascurra Teck, Eddie Limbambala, Erik J Schouten, Anthony Harries,
To describe the supervision, monitoring and evaluation strategies used to assess the delivery of antiretroviral therapy during nationwide scale-up of treatment in Malawi.In the first quarter of 2005, the HIV Unit of the Ministry of Health and its partners (the Lighthouse Clinic; Médecins Sans Frontières-Belgium, Thyolo district; and WHO's Country Office) undertook structured supervision and monitoring of all public sector health facilities in Malawi delivering antiretroviral therapy.Data monitoring ...
Tópico(s): HIV/AIDS Impact and Responses
2006 - World Health Organization | Bulletin of the World Health Organization
John R. Forney, Chansuda Wongsrichanalai, Alan J. Magill, Leslie G. Craig, Jeeraphat Sirichaisinthop, Christian T. Bautista, R. Scott Miller, Christian F. Ockenhouse, Kent E. Kester, Naomi Aronson, E. M. Andersen, Higinio A. Quino-Ascurra, Carlos Vidal, Kimberly Moran, Clinton K. Murray, Caroline Cady DeWitt, D. Gray Heppner, Kevin C. Kain, W. Ripley Ballou, Robert A. Gasser,
ABSTRACT The Para Sight F test was developed as a pioneer industry effort in the large-scale, process-controlled production of a device for the rapid diagnosis of malaria. This device performed well in field settings but was limited to the detection of a single malaria species, Plasmodium falciparum. The Para Sight F+V assay advanced upon the Para Sight F test format by incorporating a monoclonal antibody directed against a proprietary Plasmodium vivax -specific antigen, in addition to the antibody ...
Tópico(s): Vector-borne infectious diseases
2003 - American Society for Microbiology | Journal of Clinical Microbiology
John R. Forney, Alan J. Magill, Chansuda Wongsrichanalai, Jeeraphat Sirichaisinthop, Christian T. Bautista, D. Gray Heppner, R. Scott Miller, Christian F. Ockenhouse, Alex Gubanov, Robyn Shafer, Caroline Cady DeWitt, Higinio A. Quino-Ascurra, Kent E. Kester, Kevin C. Kain, Douglas S. Walsh, W. Ripley Ballou, Robert A. Gasser,
ABSTRACT Microscopic detection of parasites has been the reference standard for malaria diagnosis for decades. However, difficulty in maintaining required technical skills and infrastructure has spurred the development of several nonmicroscopic malaria rapid diagnostic devices based on the detection of malaria parasite antigen in whole blood. The Para Sight F test is one such device. It detects the presence of Plasmodium falciparum -specific histidine-rich protein 2 by using an antigen-capture immunochromatographic ...
Tópico(s): Vector-borne infectious diseases
2001 - American Society for Microbiology | Journal of Clinical Microbiology
Antonieta Rojas de Árias, Eloísa Amália Vieira Ferro, Alba Inchausti, Marta Ascurra, Nidia Acosta, Enrique M. Rodríguez, Alain Fournet,
The insecticidal, moulting inhibition and trypanocidal effects of crude extracts of 7 Paraguayan Asteraceae were evaluated on Triatoma infestans and bloodstream forms of Trypanosoma cruzi, respectively. Both mutagenicity and toxicity were evaluated by sister chromatid exchange (SCE) in human peripheral lymphocyte culture and by the lethality test of Artemia salina. The ethanolic extracts from Chromolaena christieana (stem and bark), Achyrocline satureoides (leaves and flowers) and Mikania cordifolia ( ...
Tópico(s): Synthesis and Biological Evaluation
1995 - Elsevier BV | Journal of Ethnopharmacology
Carlos R. Ferreira, María Beatriz de Herreros,
... Institute (IICS) where he organized a cytogenetic laboratory (Ascurra 1997). The Department of Genetics within the IICS ... able to afford the costs of these services (Ascurra 2004). Chromosomal microarrays are not performed in the ... American Collaborative Study of Congenital Malformations, or ECLAMC (Ascurra 1997). Agriculture, and in particular soy cultivation, is ... found a chromosomal anomaly in 4% of cases (Ascurra et al. 2002). However, the abortion policy in ... recommended dietary intake of iodine doubles during pregnancy (Ascurra et al. 2013). Although this study was not ...
Tópico(s): Indigenous Health and Education
2014 - Wiley | Molecular Genetics & Genomic Medicine
Rony Zachariah, Roger Teck, O Ascurra, P.A. Humblet, Anthony Harries,
Malawi offers antiretroviral treatment (ART) to all HIV-positive adults who are clinically classified as being in WHO clinical stage III or IV without ‘universal’ CD4 testing. This study was conducted among such adults attending a rural district hospital HIV/AIDS clinic (a) to determine the proportion who have CD4 counts ≥350 cells/μl, (b) to identify risk factors associated with such CD4 counts and (c) to assess the validity and predictive values of possible clinical markers for CD4 counts ≥350 cells/ ...
Tópico(s): HIV Research and Treatment
2005 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
Juliane Lasarzik de Ascurra, Anna Ehrle, Ralf Einspanier, Christoph Lischer,
Autologous conditioned serum (ACS) is commonly used for the treatment of human and equine osteoarthritis (OA). The objective of this study was to investigate the influence of incubation time and incubation tube on concentrations of interleukin-1 receptor antagonist (IL-1ra), interleukin-1 beta (IL-1β), and insulin-like growth factor-1 (IGF-1) in ACS of horses with and without OA. Blood samples of 7 control horses and 6 horses with naturally occurring OA were obtained. The concentration of serum IL-1ra, ...
Tópico(s): Tendon Structure and Treatment
2019 - Elsevier BV | Journal of Equine Veterinary Science
Márcia Saraiva, Magdalena E. Ściślak, Yerisf C. Torres Ascurra, Tatiana Martí Ferrando, Nikola Zic, Cyril Henard, Pieter van West, Franziska Trusch, Vivianne G. A. A. Vleeshouwers,
Oomycetes form a phylogenetically distinct group of eukaryotic microorganisms that include some of the most notorious pathogens of plants and animals. Through the deployment of a remarkably diverse array of effector proteins, oomycete pathogens succeed to overcome host defences and cause infection. Effectors can operate extracellularly or enter living cells where they target diverse subcellular compartments. Genome sequence information indicates that oomycetes express several hundred host-translocating ...
Tópico(s): Plant Pathogens and Resistance
2022 - Elsevier BV | Fungal Biology Reviews
Romari Alejandra Martinez, Elodia Torres, Mariela Nieves, Valeria Szapkievich, S Rodríguez, Alicia Schinini, Marta Ascurra, Marta Dolores Mudry,
Abstract The tufted capuchin, Cebus apella is a New World Monkey (NWM) species widely used in biomedicine. Its genetic variability has been assessed through various genetic tools. The present study offers a cytogenetic characterization of two captive colonies of Paraguayan specimens, in order to increase the current information on the role of cytogenetic polymorphisms in management of captive capuchins, specially useful for those employed as biomedical models. G-banding confirms all individual as ...
Tópico(s): Genomics and Chromatin Dynamics
2004 - University of Florence | Caryologia
Gonzalo Espinoza-Ascurra, Iván Gonzales-Graus, Mónica Meléndez-Marón, Rufino Cabrera,
La pandemia de COVID-19 ha incrementado la magnitud de enfermedades mentales como la depresión no solo entre la población general, sino también en el personal de salud. En Perú no se conocen la prevalencia y los factores asociados con depresión en personal de salud. El objetivo es determinar la prevalencia e identificar los factores asociados con depresión en el personal de salud, en el contexto de la pandemia por SARS-CoV-2. Se realizó un estudio transversal analítico entre mayo y septiembre, 2020 ...
Tópico(s): Healthcare professionals’ stress and burnout
2021 - Elsevier BV | Revista Colombiana de Psiquiatría
Marta Ascurra, Adriana Valenzuela, Mirna Salinas, Stella Rodríguez, Giovanna Porzio, Lourdes Ortíz, Andrea C. Nunez, Pamela Álvarez,
... las reportadas para la población hispánica. Correspondencia: Marta Ascurra; Correo: marta.ascurra@gmail.com Conflicto de intereses: Los autores declaran ...
Tópico(s): Oral and Craniofacial Lesions
2019 - Sociedad Paraguaya de Pediatría | Pediatría (Asunción)
... Giovanni Buzzi para a familia em 1886 em Ascurra no Medio Vale do Itajai, Estado de Santa ...
Tópico(s): Urban Development and Societal Issues
2021 - Brazilian Journal of Development | Brazilian Journal of Development
Xiao Lin, Yerisf C. Torres Ascurra, Happyka Fillianti, Laura Dethier, Laura de Rond, Emmanouil Domazakis, Carolina Aguilera‐Galvez, Afewerki Yohannes Kiros, E. Jacobsen, Richard G. F. Visser, Thorsten Nürnberger, Vivianne G. A. A. Vleeshouwers,
Pattern-triggered immunity (PTI) in plants is mediated by cell surface-localized pattern recognition receptors (PRRs) upon perception of microbe-associated molecular pattern (MAMPs). MAMPs are conserved molecules across microbe species, or even kingdoms, and PRRs can confer broad-spectrum disease resistance. Pep-13/25 are well-characterized MAMPs in Phytophthora species, which are renowned devastating oomycete pathogens of potato and other plants, and for which genetic resistance is highly wanted. ...
Tópico(s): Plant pathogens and resistance mechanisms
2023 - Frontiers Media | Frontiers in Plant Science
Yerisf C. Torres Ascurra, Xiao Lin, Pieter J. Wolters, Vivianne G. A. A. Vleeshouwers,
The identification, understanding, and deployment of immune receptors are crucial to achieve high-level and durable resistance for crops against pathogens. In potato, many R genes have been identified using map-based cloning strategies. However, this is a challenging and laborious task that involves the development of a high number of molecular markers for the initial mapping, and the screening of thousands of plants for fine mapping. Bulked segregant RNA-Seq (BSR-Seq) has proven to be an efficient ...
Tópico(s): Plant-Microbe Interactions and Immunity
2021 - Springer Science+Business Media | Methods in molecular biology
Rafael José Bona, Fabrícia Durieux Zucco, Bruna José Fontoura, Cynthia Morgana Boos de Quadros,
... analisar a percepção dos professores da cidade de Ascurra/SC sobre o uso de livro didático da ...
Tópico(s): Science and Education Research
2023 - UNIVERSIDADE FEDERAL DE GOIÁS | Revista Inter-Ação
Produção Nacional
Revisado por pares
Edith F. Legal, Marta Ascurra, Gislaine Custódio, Horacio Legal-Ayala, Magna Monteiro, Celeste Vega, María José Fernández-Nestosa, Sonia Vega, Elis R. Sade, Izabel M.M. Coelho, Enilze M.S.F. Ribeiro, Iglenir João Cavalli, Bonald C. Figueiredo,
The tumor suppressor gene TP53 is the most frequently mutated gene in human cancer, and the germline TP53 R337H mutation is the most common mutation reported to date. However, this mutation is associated with a lower cumulative lifetime cancer risk than other mutations in the p53 DNA-binding domain. A detailed statistical analysis of 171,500 DNA tests in Brazilian neonates found that 0.27% of the general population is positive for this mutation, and some of the estimated 200,000 Brazilian R337H ...
Tópico(s): Viral-associated cancers and disorders
2015 - Elsevier BV | Cancer Epidemiology
María Beatriz de Herreros, Marta Ascurra, R Franco,
El sindrome de Williams, sindrome de Williams- Beuren, hipercalcemia idiopatica o sindrome de estenosis aortica supravalvular, es un desorden de etiologia genetica caracterizado por facies dismorfica con caracteristicas tipicas, retraso mental, deficiencia del crecimiento, anomalias del tejido conectivo, anomalias cardiovasculares, una personalidad tipica y, a veces, hipercalcemia en la infancia. La frecuencia de este sindrome ha sido estimada en 1 en 10000 a 20000 nacimientos. La causa del mismo, ...
Tópico(s): Williams Syndrome Research
2007 - Universidad Nacional de Asunción | Memorias del Instituto de Investigaciones en Ciencias de la Salud
Lourdes Ortiz Paranza, Marta Cristina Sanabria, Laura González, Marta Ascurra,
Introducción: El estado nutricional adecuado resulta fundamental en los pacientes con Fibrosis QuÃstica (FQ) debido a que incide sobre la función pulmonar y la mortalidad de los mismos.
Tópico(s): Cystic Fibrosis Research Advances
2017 - Sociedad Paraguaya de Pediatría | Pediatría (Asunción)
Mónica Ruoti, Mónica Ruoti, Graciela Rojas de Torres, M Ontano, S Rodríguez, Marta Ascurra,
Los defectos del tubo neural (DTN) incluyen un amplio espectro de malformaciones congenitas. La mas frecuente es la espina bifida abierta que cursa con grados variables de paralisis de las extremidades inferiores y alteraciones vesicales e intestinales. Actualmente se pueden reducir los DTN mediante el acido folico (AF). El objetivo principal de este estudio fue determinar el conocimiento periconcepcional de AF. Se realizo un cuestionario a 800 mujeres puerperas, internadas en la Catedra de Ginecologia ...
Tópico(s): Congenital Anomalies and Fetal Surgery
2016 - Universidad Nacional de Asunción | Memorias del Instituto de Investigaciones en Ciencias de la Salud
Marta Ascurra, Edgar Giménez Caballero, Margarita Samudio,
INTRODUCCIONLa Cobertura Universal de Salud (CUS) es uno de los conceptos más poderosos de la salud pública para llevar a un ámbito concreto lo que se expresa como el derecho a la salud de la población.Esta universalización se entiende como la disponibilidad, acceso y utilización efectiva de servicios de salud integrales cuando se necesita sin que la persona o la familia tenga que incurrir en gastos excesivos o incluso correr riesgo de una ruina financiera o empobrecimiento a causa de ello (1).Para ...
Tópico(s): Hemoglobinopathies and Related Disorders
2015 - Universidad Nacional de Asunción | Memorias del Instituto de Investigaciones en Ciencias de la Salud
Mara B. de Herreros, Marta Ascurra,
El sindrome de Masa, Sindrome de Bianchine-Lewis, Sindrome de Gareis- Masson, Sindrome de retardo mental ligado al X y pulgar incluido, retardo mental con pulgar en aduccion o retardo mental con pulgar incluido congenito, Sindrome de CRASH; es una forma de retardo mental raro, de etiologia recesiva ligada al X. Los criterios mayores de diagnostico son: retardo mental, afasia, marcha arrastrando los pies y aduccion de los pulgares, de donde viene su nombre por las siglas en ingles (Mental retardation, ...
Tópico(s): Genomics and Rare Diseases
2005 - Universidad Nacional de Asunción | Memorias del Instituto de Investigaciones en Ciencias de la Salud
S Rodríguez, Norma Monjagata, Marta Ascurra,
La evidencia citogenetica de una trisomia del cromosoma 9, ya sea de todo o parte del brazo corto, con o sin trisomia para el brazo largo, produce retardo mental y caracteristicas fisico clinicas constantes. Se presenta a una nina de 2 anos y seis meses de edad, derivada al consultorio de genetica por talla baja, hipoacusia, ausencia del lenguaje. Primera hija, de padres no consanguineos, padre de 31 anos de edad y madre de 29 anos con prenatal controlado. Al examen fisico presenta una circunferencia ...
Tópico(s): Genomics and Rare Diseases
2005 - Universidad Nacional de Asunción | Memorias del Instituto de Investigaciones en Ciencias de la Salud
... Deolinda Maciel; Father Alberto Leon, and Dr. Marta Ascurra, among others.
Tópico(s): Biomedical Ethics and Regulation
2009 - Springer Nature (Netherlands) | Philosophy and medicine
Christian Alexander Yataco-Wilcas, Alberto Salazar-Ascurra, Bruno Eduardo Díaz-Llanes, Yosimar Salomón Coasaca-Tito, Luis Alberto Lengua-Vega, Cristian Eugenio Salazar-Campos,
Background: The foramen magnum, as an anatomical structure, holds clinical and functional significance due to its strategic location in the craniovertebral transition. A detailed understanding of its dimensions and shapes is crucial for better comprehension of related pathologies and for enhancing neurosurgical techniques within a specific population. The objective is to measure precise morphometric reference points of the foramen magnum in individuals of Peruvian ancestry, aiming to establish specific ...
Tópico(s): Spine and Intervertebral Disc Pathology
2024 - Medknow | Surgical Neurology International