Víctor Manuel Magdaleno-Madrigal, Alejandro Valdés‐Cruz, David Martı́nez-Vargas, Adrián Martínez, Salvador Almazán, Rodrigo Fernández‐Mas, Augusto Fernández‐Guardiola,
This work analyzed the effect of electrical stimulation of the nucleus of the solitary tract (NTS) on the development of electrical amygdaloid kindling (AK) in freely moving cats.Nine male adult cats with implanted electrodes in both amygdalae (basolateral nucleus), both lateral geniculate bodies, left NTS, and both prefrontal cortices were used. Electromyogram and electrooculogram also were recorded. The AK was performed every 24 h (1-s train, 1-ms pulses, 60 Hz, 300-600 microA). The NTS was stimulated ...
Tópico(s): Neuroscience and Neural Engineering
2002 - Wiley | Epilepsia
Alejandro Valdés‐Cruz, Víctor Manuel Magdaleno-Madrigal, David Martı́nez-Vargas, Rodrigo Fernández‐Mas, Salvador Almazán‐Alvarado, Adrián Martínez, Augusto Fernández‐Guardiola,
The effect of electrical vagus nerve stimulation (VNS) on sleep and behavior was analyzed in freely moving cats. Eight cats were prepared for 23-h sleep recordings. The left vagus nerve of four of them was stimulated during 1 min, five times at 1-h intervals, for 5 days. The VNS induces: ipsilateral myosis, blinking, licking, abdominal contractions, upward gaze, swallowing, and eventually yawning and compulsive eating, as well as an increase of ponto-geniculate–occipital (PGO) wave density and of ...
Tópico(s): Neuroscience of respiration and sleep
2002 - Elsevier BV | Progress in Neuro-Psychopharmacology and Biological Psychiatry
R. Cruz‐Martínez, Antonio Méndez, J. Dueñas‐Riaño, Ricardo Ordorica‐Flores, Jaime Nieto‐Zermeño, P. Malagón‐Salazar, C. Medina‐Noyola, Carlos Rebolledo-Fernández,
... Querétaro, Mexico; ‡Unidad de Investigación en Neurodesarrollo 'Dr Augusto Fernández Guardiola', Instituto de Neurobiología, Universidad Nacional Autónoma de ...
Tópico(s): Neonatal Respiratory Health Research
2015 - Wiley | Ultrasound in Obstetrics and Gynecology
José Alejandro Cano, Abraham Allec Londoño Pineda, Emiro Antonio Campo, Sergio Augusto Fernández Henao,
This study analyzes the preferences and perceptions of consumers in e-marketplaces to design and guide sustainable business models based on economic, social, environmental, and technological dimensions. The results are based on a sample of 387 respondents to analyze the main reasons and benefits for using e-marketplaces, the preferences, and perceptions of consumers regarding sustainability dimensions in e-marketplaces, and the assessment of technological features of digital platforms. Using descriptive ...
Tópico(s): Digital Marketing and Social Media
2023 - Springer Science+Business Media | Journal of Open Innovation Technology Market and Complexity
Cecilia Eugenia María Grossi, Elisa Fantino, Federico Serral, Myriam S. Zawoznik, Darío Augusto Fernandez Do Porto, Rita M. Ulloa,
A Gram-negative pink-pigmented bacillus (named 2A) was isolated from Solanum tuberosum L. cv. Desirée plants that were strikingly more developed, presented increased root hair density, and higher biomass than other potato lines of the same age. The 16S ribosomal DNA sequence, used for comparative gene sequence analysis, indicated that strain 2A belongs to the genus Methylobacterium. Nucleotide identity between Methylobacterium sp. 2A sequenced genome and the rest of the species that belong to the ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
2020 - Frontiers Media | Frontiers in Plant Science
Brigitte Leblon, Pedro Augusto Fernández García, Steven Oldford, David A. MacLean, Mike Flannigan,
In Canada, fire danger is rated by the Canadian forest fire danger rating system (CFFDRS). One of its components is the fire weather index (FWI) system, which has among others the drought code (DC). DC is used here as a surrogate of dead forest fuel moisture. DC values were computed from weather data acquired between 1993 and 1999 and compared to 10-day composite NOAA-AVHRR images acquired over Canadian northern boreal forests. They were yearly correlated with single compositing period and cumulative ...
Tópico(s): Fire effects on ecosystems
2006 - Elsevier BV | International Journal of Applied Earth Observation and Geoinformation
Patricia de Gortari, R.M. Uribe, Arlene García-Vázquez, Argel Aguilar‐Valles, Ana Laura Martínez, Alejandro Domínguez Valdés, Jean-Louis Charli, Augusto Fernández‐Guardiola, Patricia Joseph‐Bravo,
Subthreshold electrical stimulation of the amygdala (kindling) activates neuronal pathways increasing the expression of several neuropeptides including thyrotropin releasing-hormone (TRH). Partial kindling enhances TRH expression and the activity or its inactivating ectoenzyme; once kindling is established (stage V), TRH and its mRNA levels are further increased but TRH-binding and pyroglutamyl aminopeptidase II (PPII) activity decreased in epileptogenic areas. To determine whether variations in TRH ...
Tópico(s): Neuroscience and Neuropharmacology Research
2005 - Elsevier BV | Neurochemistry International
Augusto Fernández‐Guardiola, Ana Laura Martínez, Alejandro Valdés‐Cruz, Víctor Manuel Magdaleno-Madrigal, Daniel Godoy Martinêz, Rodrigo Fernández‐Mas,
Summary: Purpose : To analyze the effect of prolonged (daily) electrical vagus nerve stimulation (VNS) on daily amygdaloid kindling (AK) in freely moving cats. Methods : Fifteen adult male cats were implanted in both temporal lobe amygdalae, both lateral geniculate bodies, and prefrontal cortices. A bipolar hook (5‐mm separation) stainless steel electrode also was implanted in the unsectioned left vagus nerve. AK only was performed on five of the cats as a control. The remaining 10 cats were recorded under ...
Tópico(s): Urinary Bladder and Prostate Research
1999 - Wiley | Epilepsia
Patricia de Gortari, Augusto Fernández‐Guardiola, Adrián Martínez, Miguel Cisneros, Patricia Joseph‐Bravo,
Pyroglutamyl peptidase II (PPII) is a neuronal ectoenzyme responsible for thyrotropin releasing hormone (TRH) degradation at the synaptic cleft. PPII, heterogeneously distributed in different brain regions and adenohypophysis, is regulated under various endocrine conditions where TRH is involved in thyrotropin or prolactin regulation but only at the adenohypophyseal level. TRH can downregulate PPII activity in cultured adenohypophyseal cells. TRH present in extrahypothalamic brain areas has been postulated ...
Tópico(s): Aldose Reductase and Taurine
1995 - Elsevier BV | Brain Research
Augusto Fernández‐Guardiola, Adrián Martínez, Rodrigo Fernández‐Mas,
The effect of repeated Na-penicillin (PCN) microinjections in the temporal lobe amygdala (AM) of free-moving cats was investigated in order to establish if kindling epileptogenesis is possible with this procedure. The cortical propagation of the PCN-induced post-discharge in AM and the sequence of behavioral changes induced by PCN were similar to those of AM electrical kindling. Nevertheless, the epileptogenic effect of PCN had a different evolution from that of electrical kindling, since some PCN ...
Tópico(s): Memory and Neural Mechanisms
1995 - Elsevier BV | Epilepsy Research
José María Calvo, Augusto Fernández‐Guardiola,
We analyzed the electrical activity of the basolateral amygdala (BLA), anterior and posterior regions of the cingulate gyrus (A-CG and P-CG), the dorsal hippocampus (DH), the anterior ventral thalamic nucleus (AVTN), and the sensory motor cortex during the rapid eye movements and ponto-geniculo-occipital (PGO) activity of REM sleep in cats in chronic preparation. Polygraphic recordings and computational peri event averages using the phasic contractions of the lateral rectus muscle (LR) of the eyeball ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
1984 - Oxford University Press | SLEEP
Carlos Paz, Efraín Reygadas, Augusto Fernández‐Guardiola,
Polygraphic sleep studies were conducted in six cats just before cerebellectomy and 3 and 10 days after the operation.These studies were continued in the four surviving animals 30, 100, 200, 300, and 315 days postoperatively.The findings confirmed the existence of two postoperative phases correlated with the degeneration of brainstem structures: an initial period (day 3) was characterized by a significant increase in wakefulness; a second, later period (days 10 and 30) was distinguished by numerous ...
Tópico(s): Zebrafish Biomedical Research Applications
1982 - Oxford University Press | SLEEP
Elizabeth Ruiz-Primo, José Luis Parra Jurado, Herrera Arturo Solís, J Maisterrena, Augusto Fernández‐Guardiola, Carlos Valverde-R,
Nine primary myxedematous patients were subjected to all-night polysomnographic recordings under the following conditions: (1) basal or myxedematous state; (2) acute replacement therapy (treatment with thyroid hormones at doses that increased weekly to the maximal replacement dose, Mrd); and (3) chronic replacement therapy (maintenance on the Mrd; euthyroid state). The most striking abnormality found in the sleep pattern during the myxedematous state was observed in both young adult (greater than 20 years ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
1982 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
José María Calvo, Raúl Alvarado, Rafael Briones, Carlos Paz, Augusto Fernández‐Guardiola,
Development of amygdaloid kindling was analyzed during REM sleep and during wakefulness. Daily evolution of electrographic and behavioral changes was significantly delayed in REM kindled rats. The number of kindling trials required to reach the first generalized convulsive seizure was also significantly increased in comparison with awake kindled animals. Changes in sleep organization were measured under REM kindling conditions. A significant increase in total sleep time and in the percentage of ...
Tópico(s): Epilepsy research and treatment
1982 - Elsevier BV | Neuroscience Letters
A. Salgado‐Benftez, Rafael Briones, Augusto Fernández‐Guardiola,
Summary: A penicillin focus was induced in the postcruciate region of the cerebral cortex of the cat. Analyzing the Purkinje cell unit responses to consecutive interictal paroxysms, 60% of the cells studied (total number, 148) were found to respond with activation and 25%, with deactivation; the others were not uniform in their responses. These different response patterns were attributed to the high patchy topographic relation between the cerebral cortex and the cerebellar system as well as to the ...
Tópico(s): Neonatal and fetal brain pathology
1982 - Wiley | Epilepsia
Osvaldo Vindrola, Rafael Briones, Miguel Asai, Augusto Fernández‐Guardiola,
Tópico(s): Pain Mechanisms and Treatments
1981 - Elsevier BV | Neuroscience Letters
Osvaldo Vindrola, Rafael Briones, Miguel Asai, Augusto Fernández‐Guardiola,
Brain content of leucine-enkephalin and methionine-enkephalin changes independently during kindling of the amygdala. Both peptides were measured after 4, 8, 15 and 21 days of stimulation. Leuenkephalin showed a progressive increase during the kindling: the results on the 4th day did not differ significantly from the controls, whereas those on the 8th day displayed an increase only in the stimulated left hemisphere and those on the 15th day showed an increase in both hemispheres. This increase was ...
Tópico(s): Neuroscience and Neuropharmacology Research
1981 - Elsevier BV | Neuroscience Letters
Miguel Condés‐Lara, José María Calvo, Augusto Fernández‐Guardiola,
Stimulation (1/10 sec, 1–2 msec) of the tooth pulp of volunteers was carried out for 120 min at an intensity that produced bearable pain. Cortical evoked potentials, electroencephalographic activity, electromyograms of the superciliary and masseter muscles and galvanic skin response were recorded. Every 30 min, without suspending the stimulation, the subjects were questioned with respect to the sensations accompanying the stimuli. A progressive decrease in all polygraphic responses was observed which ...
Tópico(s): Pediatric Pain Management Techniques
1981 - Lippincott Williams & Wilkins | Pain
Carlos M. Contreras, Teresa González-Estrada, Daniel Zarabozo, Augusto Fernández‐Guardiola,
Motor incoordination, euphoria and hallucinations are symptoms reported for humans voluntarily intoxicated by industrial solvents. An epileptic-like consciousness impairment has also been noted. The present paper describes a technique used for the experimental study of solvent intoxication in which toluene and benzene can be applied directly into the trachea of freely moving cats with chronically implanted electrodes. This technique permits the control of solvent dose and time of exposure. Results ...
Tópico(s): Neuroscience and Neural Engineering
1979 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Carlos Valverde-R, L.S. Pastrana, Jorge Alejandro Cebada Ruíz, Herrera Arturo Solís, José Luis Parra Jurado, C.M. Sordo, Augusto Fernández‐Guardiola, J Maisterrena,
Amphetamine, a clinically used sympathomimetic central-acting drug, was administered in Spansule capsules in a blind schedule to 8 normal obse volunteers in a daily (8 a.m.) single 15 dose for 7 days. The study, conducted in the metabolic ward, included two 7 day placebo periods (pre- and post-drug). During the 1st placebo period, all subjects exhibited within the 1st 2 h of sleep a clear and significant nocturnal increase of growth hormone (GH) closely related with sleep stages 3 and 4. Thyrotropin ( ...
Tópico(s): Regulation of Appetite and Obesity
1976 - Karger Publishers | Neuroendocrinology
Augusto Fernández‐Guardiola, Fructuoso Ayala,
The electrical activity of several cortical and subcortical structures was analyzed in cats during electrically and pentamethylenetetrazol-induced seizures. These activities were compared with the spinal monosynaptic reflex variations during the same seizures. The following results are described:1.1. The monosynaptic spinal reflex is initially facilitated during the tonic phase and when it is elicited in the vicinity of a clonic wave.2.2. In the last stages of the seizure, the monosynaptic spinal ...
Tópico(s): EEG and Brain-Computer Interfaces
1971 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Fernando Antón‐Tay, José-Luis Dı́az, Augusto Fernández‐Guardiola,
Various doses of melatonin were administered to normal and epileptic subjects. Increase of EEG alpha activity, sleep, imagery, and a feeling of well-being and elation were found. A decrease in paroxistic grapho-elements of the epileptic patients was also noticed. When two parkinsonians received 1.2 g of melatonin orally for four weeks, a striking improvement in the symptoms and signs of the disease was detected.
Tópico(s): Sleep and Wakefulness Research
1971 - Elsevier BV | Life Sciences
Augusto Fernández‐Guardiola, Thalı́a Harmony, Eduardo R. S. Roldán,
1. The visual responses (ERG, evoked potentials of the optic chiasm, LGB and visual cortex) and the pupillary diameter were recorded simultaneously with each photic stimulation. 2. Changes in the amplitude of the evoked responses along the visual pathways were produced by slight ocular movements. 3. Spontaneous and centrally induced pupillary movements modified the visual responses. The magnitude of the b wave of the ERG and of the early deflection of the chiasmatic potential show a close relationship ...
Tópico(s): Retinal Development and Disorders
1964 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Robert S. Dow, Augusto Fernández‐Guardiola, E Manni,
Tópico(s): Neural dynamics and brain function
1962 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Robert S. Dow, Augusto Fernández‐Guardiola, E Manni,
The cerebellar influence on the cobalt experimental epilepsy has been investigated in unrestrained, unanesthetized rats by stimulation, total removal and temporary cooling of the cerebellum. Cerebellar stimulation generally provoked inhibition of the epileptic waves produced in the brain by cobalt application and depressed the sensory responses in the cerebral cortex. The occasional reversed facilitatory effects of the stimulation are discussed in the light of other peculiar effects of cerebellar ...
Tópico(s): Amino Acid Enzymes and Metabolism
1962 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
Augusto Fernández‐Guardiola, E Manni, Jacob Hayes Wilson, Robert S. Dow,
Cerebellar unitary discharge has been recorded with microelectrodes from cerebellar cortex and nuclei before, during, and after different convulsive patterns induced in curarized rats by electrical stimulation of the brain, by intraperitoneal injection of convulsant drugs (Megimide or Metrazol), and by anoxia. It has been compared simultaneously with the electrical activity of the cerebral cortex (sensorimotor area) recorded either with microelectrodes or with concentric electrodes. Low-voltage, single ...
Tópico(s): Neonatal and fetal brain pathology
1962 - Elsevier BV | Experimental Neurology
Augusto Fernández‐Guardiola, Enrique Roldán R., Ma.Luisa Fanjul, Consuelo Castells,
Tópico(s): Neuroscience and Neuropharmacology Research
1961 - Elsevier BV | Electroencephalography and Clinical Neurophysiology
R Naquet, H Régis, M. Fischer-Williams, Augusto Fernández‐Guardiola,
Journal Article VARIATIONS IN THE RESPONSES EVOKED BY LIGHT ALONG THE SPECIFIC PATHWAYS Get access R. NAQUET, R. NAQUET From the Department of Neurobiology, University of Marseille Search for other works by this author on: Oxford Academic PubMed Google Scholar H. REGIS, H. REGIS From the Department of Neurobiology, University of Marseille Search for other works by this author on: Oxford Academic PubMed Google Scholar M. FISCHER-WILLIAMS, M. FISCHER-WILLIAMS From the Department of Neurobiology, University ...
Tópico(s): Neural dynamics and brain function
1960 - Oxford University Press | Brain
Jairo Muñóz-Delgado, Gustavo Luna‐Villegas, Ricardo Mondragón‐Ceballos, Augusto Fernández‐Guardiola,
There are reasons to consider incomplete the description of sleep in many non-human primate species. Recording animals by highly sensitive videos to obtain detailed descriptions of nighttime behavior and evidence of muscle activity while in a resting posture, seems a promising approach to the non-invasive study of sleep in non-human primates. The present work describes the use of ultrasensitive videocameras to record and analyze spontaneous nighttime behaviors in captive non-human primates. Its ...
Tópico(s): Primate Behavior and Ecology
1995 - Wiley | American Journal of Primatology
Augusto Fernández‐Guardiola, V. M. Okujava, Elisa Guma,
SUMMARY In “encáephale isole” preparations eye movements and depression of the electromyo‐gram of neck muscles were recorded during interclonic electrical silences and coinciding with the arrest of the seizures elicited by electrocortical stimulation. In the intact curarized animal the interclonic periods of electrical silence and arrest of seizure discharges were accompanied by a low voltage fast activity in dorsal limbic structures, pontine, and mesencephalic nuclei. At the end of the seizure, ...
Tópico(s): EEG and Brain-Computer Interfaces
1968 - Wiley | Epilepsia