... TG-02-2020-0030Ximena Alejandra Flechas Chaparro, Leonardo Augusto de Vasconcelos Gomes Pivot decisions in startups: a systematic literature ...
Tópico(s): Housing Market and Economics
1939 - University of Chicago Press | Journal of Political Economy

Leonardo Augusto de Vasconcelos Gomes, Rafael Augusto Seixas Reis de Paula, Ana Lúcia Figueiredo Facin, Vinícius Chagas Brasil, Mário Sérgio Salerno,
Setting the right approach for new product development (NPD) in the presence of uncertainty remains an ongoing debate in innovation management. Stage‐gate systems (SGS) and agile methodology (AM) are the dominant approaches. Recently, hybrid approaches (combining SGS and AM) have been proposed. Although these hybrid approaches represent a significant development in NPD, combining them without considering their design principles might lead to contradictory and competing conceptual formulations, thus ...
Tópico(s): Design Education and Practice
2021 - Wiley | R and D Management

Carlos Augusto Carvalho de Vasconcelos, João Augusto Farias de Oliveira, L COSTA, Rubem Carlos Araújo Guedes,
AbstractAbstractThis study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72 h prior to the SD-recordings. The SD was recorded continuously for 3-4 h in 13 well-nourished (W) and 15 early-malnourished (M) adult rats. One to two hours after the beginning of the recording session, a sub-convulsing intraperitoneal (i.p.) injection of pilocarpine ( ...
Tópico(s): Sleep and related disorders
2004 - Taylor & Francis | Nutritional Neuroscience

Leonardo Augusto de Vasconcelos Gomes, Vinícius Chagas Brasil, Rafael Augusto Seixas Reis de Paula, Ana Lúcia Figueiredo Facin, Frederico César de Vasconcelos Gomes, Mário Sérgio Salerno,
Managers of exploratory projects might face uncertainties over long timeframes at different levels (e.g., project, portfolio, organization, and network). Although literature offers some guidance on how to deal with uncertainties (mainly at the project level), there is a need for more empirical ground and theoretical development of a systemic approach to the management of uncertainties. To fill this gap, this article employs a multiple case approach in two established firms, investigating six exploratory ...
Tópico(s): Construction Project Management and Performance
2019 - SAGE Publishing | Project Management Journal

Roberta Vasconcellos Menezes de Azevedo, Eduardo A. Oliveira, Mônica Maria de Almeida Vasconcelos, Breno Augusto Campos de Castro, Fabiana Resende Pereira, Nathalia Filgueiras Vilaça Duarte, Patricia Moraes Resende de Jesus, Giovana Teixeira Branco Vaz, Eleonora Moreira Lima,
The lower urinary tract dysfunction (LUTD) corresponds to changes in the filling or emptying of urine caused by neurogenic, anatomical and functional alterations.To evaluate the impact of treatment in children and adolescents with LUTD.Historical cohort of 15 year follow-up with the participation of 192 patients (123F, 69M), aged 0.1 to 16.8 years, analyzed at admission (T0) and at final follow-up (T1). Most patients belong to a neurologic bladder dysfunction group (60.4%). The treatment was uroterapy ...
Tópico(s): Pelvic floor disorders treatments
2014 - Sociedade Brasileira de Nefrologia | Brazilian Journal of Nephrology

André Belico de Vasconcelos, Mateus Augusto de Carvalho Santana, Alexandre Martins Costa Santos, Marcelo M. Santoro, M. A. Lagares,
Microscopy has been used in the routine evaluation of sperm metabolism. Nevertheless, it has limited capacity to preview male fertility. As calorimetry may be used to evaluate directly the metabolic activity of a biological system, the aim of this study was to use microcalorimetry as an additive method for sperm metabolism evaluation of cooled equine semen. Two ejaculates of four stallions were collected and motility, viability (eosin 3%) and membrane functional integrity (hyposmotic swelling test) ...
Tópico(s): thermodynamics and calorimetric analyses
2010 - Wiley | Andrologia

Ana Lúcia Figueiredo Facin, Leonardo Augusto de Vasconcelos Gomes, Mauro de Mesquita Spínola, Mário Sérgio Salerno,
Platforms have been considered as a paradigm for managing new product development and innovation. Since their introduction, studies on platforms have introduced multiple conceptualizations, leading to a fragmentation of research and different perspectives. By systematically reviewing the platform literature and combining bibliometric and content analyses, this paper examines the platform concept and its evolution, proposes a thematic classification, and highlights emerging trends in the literature. ...
Tópico(s): Business Strategy and Innovation
2016 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Engineering Management

Leonardo Augusto de Vasconcelos Gomes, Ana Lúcia Figueiredo Facin, Mário Sérgio Salerno, Rodrigo Kazuo Ikenami,
The innovation ecosystem construct has emerged as a promising approach in the literature on strategy, innovation and entrepreneurship. It draws upon former business ecosystem literature. However, the term innovation ecosystem has been employed in very polysemic and sometimes competing ways. Many adjectives used with reference to innovation ecosystems render the consolidation of the construct more difficult - which its characteristics, boundaries and relation with other, to some extent competing, constructs, ...
Tópico(s): Innovation and Knowledge Management
2016 - Elsevier BV | Technological Forecasting and Social Change

Vinícius Chagas Brasil, Mário Sérgio Salerno, Leonardo Augusto de Vasconcelos Gomes,
Real Options (RO) has been indicated to valuate projects with high uncertainty. However, literature points to challenges and asks for an organizational understanding of its use. So: Why do managers search for the RO approach to valuate radical innovation projects? Based on five in-depth case studies, we discuss hidden organizational and managerial issues related to the search for RO to valuate radical innovation. We argue that managers search for RO to cope with the "paradox of organizational fit", ...
Tópico(s): Intellectual Capital and Performance Analysis
2018 - Elsevier BV | Journal of Engineering and Technology Management

Antonio Carlos Braz, Adriana Marotti de Mello, Leonardo Augusto de Vasconcelos Gomes, Paulo Tromboni de Souza Nascimento,
The bullwhip effect, or how uncertainty associated with the end customers' demand propagates through the entire supply chain, has been widely discussed in supply-chain management literature. Although there is a well-established research stream on the causes and mitigating factors for the bullwhip effect in forward supply chains, few studies have investigated how this phenomenon manifests itself in closed-loop supply chains. We argue that this phenomenon can affect the supply chain's environmental ...
Tópico(s): Supply Chain and Inventory Management
2018 - Elsevier BV | Journal of Cleaner Production

Leonardo Augusto de Vasconcelos Gomes, Ana Lúcia Figueiredo Facin, Flávio Hourneaux,
Research on performance management (PM) of networks and radical innovation has largely developed along two isolated paths. On the one hand, a growing body of knowledge addresses the use of performance management systems in the context of networks (notably for production and incremental innovation). On the other hand, radical innovation scholars have shown how innovation initiatives that are more uncertain demand the use of new approaches (e.g., new project management routines or different evaluative ...
Tópico(s): Accounting and Organizational Management
2019 - Wiley | Creativity and Innovation Management

Ximena Alejandra Flechas Chaparro, Leonardo Augusto de Vasconcelos Gomes, Paulo Tromboni de Souza Nascimento,
Purpose The purpose of this paper is to identify how project portfolio selection (PPS) methods have evolved and which approaches are more suitable for radical innovation projects. This paper addressed the following research question: how have the selection approaches evolved to better fit within radical innovation conditions? The current literature offers a number of selection approaches with different and, in some cases, conflicting nature. Therefore, there is a lack of understanding regarding when ...
Tópico(s): Innovation and Knowledge Management
2019 - Emerald Publishing Limited | Revista de Gestão

Leonardo Augusto de Vasconcelos Gomes, Henry Lopez‐Vega, Ana Lúcia Figueiredo Facin,
Consider an interorganizational open innovation project, in which different organizations cooperate to generate value for clients or to solve a technological problem. In this setting, both the focal firm and the partners face uncertainties over time (e.g., technological uncertainties, market uncertainties) and, therefore, the performance of the focal firm and the overall interorganizational project depend on that firm's ability to assess potential uncertainties. The process of diffusion of a particular ...
Tópico(s): Open Source Software Innovations
2020 - Elsevier BV | International Journal of Project Management

Leonardo Augusto de Vasconcelos Gomes, Aline Mariane de Faria, Felipe Mendes Borini, Ximena Alejandra Flechas Chaparro, Matheus Graciani dos Santos, Guilherme Soares Gurgel Amaral,
Purpose Accessing and sharing dispersed knowledge in ecosystems is neither easy nor automatic. In ecosystems, focal firms should purposely create the right conditions and act to deal with dispersed knowledge. This study aims to investigate how focal firms manage dispersed knowledge in ecosystems characterized by a set of autonomous, heterogeneous, yet interdependent actors involved in experimentation under uncertainty. Design/methodology/approach Following a conceptual framework based on preceding ...
Tópico(s): Complex Systems and Decision Making
2021 - Emerald Publishing Limited | Journal of Knowledge Management

Leonardo Augusto de Vasconcelos Gomes, Ximena Alejandra Flechas Chaparro, Ana Lúcia Figueiredo Facin, Felipe Mendes Borini,
The introduction of supply chain management (SCM) between the 1980s and 1990s represented a breakthrough in the field of management. SCM provides the analytical and theoretical background to design, plan, and manage production activities involving complex chains of firms. Nowadays, both production activities and incremental and radical innovation are organized through complex networks. Innovations, especially radical ones, have unique characteristics related to production flows, which generate new ...
Tópico(s): Complex Systems and Decision Making
2021 - Elsevier BV | Technological Forecasting and Social Change

Leonardo Augusto de Vasconcelos Gomes, Ana Lúcia Figueiredo Facin, Mário Sérgio Salerno,
The propagation of uncertainty occurs when information, perceived as revealing uncertainty, spreads through the innovation ecosystem. This paper explores how entrepreneurs cope with uncertainty propagation. Drawing on four in-depth inductive case studies of innovation ecosystems, we characterise the phenomenon of uncertainty propagation and the mechanisms by which entrepreneurs might manage the same. The mechanisms are: i) identification of a protected niche; ii) use of cognitive alignment; iii) ...
Tópico(s): Private Equity and Venture Capital
2021 - Elsevier BV | Technological Forecasting and Social Change

Ximena Alejandra Flechas Chaparro, Leonardo Augusto de Vasconcelos Gomes,
Purpose Entrepreneurs' pivot decisions are poorly understood. The purpose of this paper is to review the existing literature on pivot decisions to identify the different conceptualizations, research streams and main theoretical building blocks and to offer a baseline framework for future studies on this phenomenon. Design/methodology/approach A systematic literature review of 86 peer-reviewed papers published between January 2008 and October 2020, focusing on the pivot decision in startups, was ...
Tópico(s): Innovation and Socioeconomic Development
2021 - Emerald Publishing Limited | International Journal of Entrepreneurial Behaviour & Research

Leonardo Augusto de Vasconcelos Gomes, Aline Mariane de Faria, Antonio Carlos Braz, Adriana Marotti de Mello, Felipe Mendes Borini, Aldo Roberto Ometto,
The transition of the traditional economy towards the circular economy (CE) is strongly linked to the emergence and development of ecosystems that produce a coherent circular value proposition. However, the literature on how firms create and manage circular ecosystems is unclear. We propose a theoretical framework for managing circular ecosystems involving autonomous yet interdependent actors that create and capture circular values. To achieve this goal, we conducted qualitative research through ...
Tópico(s): Service and Product Innovation
2022 - Elsevier BV | International Journal of Production Economics

Leonardo Augusto de Vasconcelos Gomes, Matheus Graciani dos Santos, Ana Lúcia Figueiredo Facin,
Firms face the challenge of creating and managing global innovation ecosystems (GIEs) to develop radical innovation. In such a situation, focal firms and their partners may deal with global and local uncertainties requiring unique managerial approaches and strategies. Consequently, uncertainty management becomes central to explaining why some ecosystems successfully develop more radical innovations while others fail in a global landscape. Prior research lacks insight into how focal firms orchestrate ...
Tópico(s): Innovation Diffusion and Forecasting
2022 - Elsevier BV | Technological Forecasting and Social Change

Leonardo Augusto de Vasconcelos Gomes, Ana Lúcia Figueiredo Facin, Lorenna Fernandes Leal, Eduardo Zancul, Mário Sérgio Salerno, Felipe Mendes Borini,
Ecosystem management (EM) encompasses all the activities required to design and manage ecosystems for distributed value creation. Although the literature represents a growing body of knowledge on the unique challenges related to operating within an ecosystem, there is a limited understanding of EM from an organisational perspective, including its general purpose (mandate and theoretical reasons), structures, boundaries, and roles. Through a rich inductive case study of five business-to-business (B2B) ...
Tópico(s): Digital Platforms and Economics
2022 - Elsevier BV | Industrial Marketing Management

Mário Sérgio Salerno, Leonardo Augusto de Vasconcelos Gomes, Débora Oliveira da Silva, Raoni Barros Bagno, Simone de Lara Teixeira Uchôa Freitas,
The innovation process has traditionally been understood as a predefined sequence of phases: idea generation, selection, development, and launch/diffusion/sales. Drawing upon contingency theory, we argue that innovation process may follow a number of different paths. Our research focuses on a clear theoretical and managerial question, i.e., how does a firm organize and plan resource allocation for those innovation processes that do not easily fit into traditional models. This question, in turn, ...
Tópico(s): Construction Project Management and Performance
2014 - Elsevier BV | Technovation

Mário de Almeida Pereira Coutinho, Elba Bandeira, Juliana Maria Coelho Maia de Almeida, Emanuelle Tenorio Albuquerque Madruga Godoi, Germana Augusto de Vasconcelos, Francisco Bandeira,
Osteoporosis and atherosclerosis share common risk factors and the association of low bone mass with increased cardiovascular morbidity and mortality has been demonstrated in some studies. Nevertheless, most studies have been focused on women and only a few on individuals with type 2 diabetes mellitus (T2DM). The measurement of carotid intimal-medial thickness (CIMT) is able to detect early atherosclerotic changes and is a predictive marker of cardiovascular events. The aim of this study was to assess ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2013 - SAGE Publishing | Clinical Medicine Insights Endocrinology and Diabetes

Leonardo Augusto de Vasconcelos Gomes, Mário Sérgio Salerno, Robert Phaal, David Probert,
Radically innovative products and services are frequently developed and commercialized by new ventures. In this context, entrepreneurs may face the challenge of coordinating a complex network of actors in the presence of individual and collective uncertainties. Previous literature on entrepreneurship has focused on how entrepreneurs manage individual uncertainties (those that affect a single firm) rather than collective uncertainties that also affect members of the innovation ecosystem, which in ...
Tópico(s): Private Equity and Venture Capital
2017 - Elsevier BV | Technological Forecasting and Social Change

Leonardo Augusto de Vasconcelos Gomes, Dánika A. Castillo-Ospina, Ana Lúcia Figueiredo Facin, Camila dos Santos Ferreira, Aldo Roberto Ometto,
The prominence of the circular ecosystem raises questions about how firms innovate by creating and enhancing circular ecosystems. Using multiple case studies of seven companies and their circular ecosystems, we propose a new framework which we refer to as circular ecosystem innovation portfolio management. This new type of portfolio management addresses three different variations on circular innovation projects: new circular ecosystem innovation, architectural circular ecosystem innovation, and ...
Tópico(s): University-Industry-Government Innovation Models
2023 - Elsevier BV | Technovation

Adriana Hofmann Trevisan, Ana Lobo, Daniel Guzzo, Leonardo Augusto de Vasconcelos Gomes, Janaina Mascarenhas,
Industry 4.0 and digital technologies might significantly impact resource optimization in a smart circular economy. However, adopting digital technologies is not easy due to barriers that may arise during this process. While prior literature offers initial insights into barriers at the firm level, these studies pay less attention to these barriers' multi-level nature. Focusing only on one particular level while ignoring others may not unleash the full potential of DTs in a circular economy. To overcome ...
Tópico(s): Recycling and Waste Management Techniques
2023 - Elsevier BV | Journal of Environmental Management

Welder Angelo Baldassini, Luis Artur Loyola Chardulo, Josineudson Augusto II de Vasconcelos Silva, Jéssica Moraes Malheiros, Victor Augusto Domingos Dias, Rafael Espigolan, Fernando Baldi, Lúcia Galvão de Albuquerque, Talita Tanaka Fernandes, Pedro de Magalhães Padilha,
Subcutaneous fat deposition measured as backfat thickness (BFT) increases protection for the bovine carcass during cooling, conferring to BFT an important characteristic for the meat industry. To study the influence of BFT on meat quality traits of Nellore bulls (Bos indicus), data from 1652 animals aged 20–24 months in feedlot finishing were used. The principal component analysis (PCA) was performed to characterise meat quality variables in longissimus thoracis muscle. Measurements comprised the rib ...
Tópico(s): Genetic and phenotypic traits in livestock
2016 - CSIRO Publishing | Animal Production Science
Vinícius Chagas Brasil, Mário Sérgio Salerno, J. P. Eggers, Leonardo Augusto de Vasconcelos Gomes,
Overview Managing an innovation portfolio is crucial for firms looking to foster radical innovation. Radical innovation, however, creates challenges for traditional portfolio management systems. When companies do not adequately distinguish between incremental and radical innovation when designing their management systems, portfolio management decision-making processes will tend to favor incremental innovation. Radical innovation requires a broader, multilevel organizational approach. We propose ...
Tópico(s): Business Strategy and Innovation
2021 - Taylor & Francis | Research-Technology Management

Leonardo Augusto de Vasconcelos Gomes, Lidyane Stephane da Silva Barros,
Market formation in sustainability transitions is characterised by deep and longstanding uncertainty. Albeit prior research provides a rich repertoire of theoretical frameworks on how incumbent firms and entrepreneurs deal with uncertainty, there is still scant literature on the role of the government in orchestrating uncertainty concerning market formation. By studying multiple cases involving an innovation agency and municipalities in Brazil, we propose a new framework composed of a distinguishing ...
Tópico(s): Innovation and Knowledge Management
2022 - Elsevier BV | Environmental Innovation and Societal Transitions

Leonardo Augusto de Vasconcelos Gomes, André Leme Fleury, Maicon Gouvêa de Oliveira, Ana Lúcia Figueiredo Facin,
• This study explores how public innovation agencies use roadmaps to promote ecosystem creation and the advancement required to develop and commercialise systemic innovations • Three years of action research in the main Brazilian Public Innovation Agency contributed to building eight roadmaps. • The action research investigates a real-world situation and its transformation, yet its generalization is limited. • We proposed a framework to integrate ecosystem policy and roadmapping and implement it in real-world ...
Tópico(s): Innovation Policy and R&D
2021 - Elsevier BV | Technological Forecasting and Social Change

Sophia Barquete, Ana Hiromi Shimozono, Adriana Hofmann Trevisan, Camila Gonçalves Castro, Leonardo Augusto de Vasconcelos Gomes, Janaina Mascarenhas,
The circular economy (CE) aims to minimize the environmental impact caused throughout the entire production chain, which can be achieved by implementing circular strategies in collaboration with different actors within a business ecosystem. Although the close relationship between CE and business ecosystem concepts, which originated the term “circular ecosystem”, research about this subject is necessary, given the scarcity of empirical studies addressing the phenomenon. Therefore, this study aims to ...
Tópico(s): Environmental Sustainability in Business
2022 - Multidisciplinary Digital Publishing Institute | Sustainability