... Occupational Therapy and Obsessive-Compulsive Disorder Stephanie M. Bavaro Stephanie M. Bavaro Stephanie M. Bavaro, OTR, is a First Lieutenant in the United ... PubMed Google Scholar Author & Article Information Stephanie M. Bavaro wrote this article in her private capacity. No ... Cite Icon Cite Search Site Citation Stephanie M. Bavaro; Occupational Therapy and Obsessive-Compulsive Disorder. Am J ...
Tópico(s): Occupational Therapy Practice and Research
1991 - American Occupational Therapy Association | American Journal of Occupational Therapy
Gianluca Trifirò, Valentina Isgrò, Ylenia Ingrasciotta, Valentina Ientile, Luca L’Abbate, Saveria Serena Foti, Valeria Belleudi, Francesca Romana Poggi, Andrea Fontana, Ugo Moretti, Riccardo Lora, Alberto Sabaini, Ilenia Senesi, Carla Sorrentino, Maria R. Puzo, Angela Padula, Mariano Fusco, Roberta Giordana, Valentina Solfrini, Aurora Puccini, Paola Rossi, Stefania Del Zotto, Olivia Leoni, Martina Zanforlini, Domenica Ancona, Vito Bavaro, Donatella Garau, Stefano Ledda, Salvatore Scondotto, Alessandra Allotta, Marco Tuccori, Rosa Gini, Giampaolo Bucaneve, David Franchini, Anna Cavazzana, Valeria Biasi, Stefania Spila Alegiani, Marco Massari, Gianluca Trifirò, Ugo Moretti, Riccardo Lora, Alberto Sabaini, Valentina Isgrò, Ylenia Ingrasciotta, Valentina Ientile, Luca L’Abbate, Saveria Serena Foti, Stefania Spila Alegiani, Valeria Belleudi, Francesca Romana Poggi, Andrea Fontana, Marco Massari, Ilaria Andretta, Matilde Tanaglia, Ilenia Senesi, Carla Sorrentino, Maria Rosalia Puzo, Angela Padula, Antonio Carriero, S. Sassano, Caterina De Sarro, Simona Mirarchi, Caterina Palleria, Caterina De Sarro, Mariano Fusco, Roberta Giordana, Marianna Balestrieri, Stefania Rostan, Annalisa Capuano, Francesca Futura Bernardi, Ugo Trama, Alessandro Russo, Maria Grazia Fumo, Valeria Belleudi, Francesca Romana Poggi, Antonio Addis, Felice Musicco, Valentina Solfrini, Ester Sapigni, Aurora Puccini, Ilaria Mazzetti, Debora Podetti, Anna Maria Potenza, Victoria Nikitina, Rita Ricciardelli, Nazanin Mogheiseh, Silvia Croce, Paola Rossi, A. Pettinelli, Stefania Del Zotto, Lucian Ejlli, Olivia Leoni, Ida Fortino, Michele Ercolanoni, Arianna Mazzone, Andrea Angelo Nisic, Simone Schiatti, Monica Ludergnani, Martina Zanforlini, Mauro Mancini, Luigi Patregnani, Paolo Fabbietti, Elisa Antonicelli, Antea Maria Pia Mangano, Annalisa Campomori, Silvana Anna Maria Urru, Giorgio Costa, Giovanni Maria Guarrera, Domenica Ancona, Vito Bavaro, Paolo Stella, Donatella Garau, Enrico Serra, Stefano Ledda, Paolo Carta, Salvatore Scondotto, Alessandra Allotta, Rosa Gini, Marco Tuccori, Alfredo Vannacci, Ersilia Lucenteforte, M Parrilli, Irma Convertino, Giampaolo Bucaneve, Marcello De Giorgi, David Franchini, R Rocchi, Mariangela Rossi, Giovanna Scroccaro, Anna Cavazzana, Valeria Biasi, Paola Deambrosis, Giampietro Grindelli, Eliana Ferroni,
Biological drugs have improved the management of immune-mediated inflammatory diseases (IMIDs) despite being associated with important safety issues such as immunogenicity, infections, and malignancies in real-world settings.The aim of this study was to explore the potential of a large Italian multi-database distributed network for use in the postmarketing surveillance of biological drugs, including biosimilars, in patients with IMID.A retrospective cohort study was conducted using 13 Italian regional ...
Tópico(s): Tuberculosis Research and Epidemiology
2021 - Adis, Springer Healthcare | BioDrugs
Jesús M. González-Pérez, Ricardo Remond-Roa, Onofre Rullan-Salamanca, Sònia Vives-Miró,
... the spaces of social reproduction of Varadero and Bávaro-Punta Cana. The existence of human settlements before ...
Tópico(s): Cruise Tourism Development and Management
2016 - Elsevier BV | Habitat International
Lynn M. Bavaro, Paolo. Montangero, Jerome B. Keister,
... reductive elimination of hydrogen on triruthenium clustersLynn M. Bavaro, Paolo Montangero, and Jerome B. KeisterCite this: J. ...
Tópico(s): Catalytic Processes in Materials Science
1983 - American Chemical Society | Journal of the American Chemical Society
Alfonso de Jesús Jiménez Martínez,
... otras ciudades del Turismo en el Caribe (Varadero, Bávaro-Punta Cana),editado por Jesús M. González, participan ... contrapunto temático de las ciudades analizadas (Varadero y Bávaro-Punta Cana), las diferentes situaciones que se encuentran ...
Tópico(s): Regional Development and Innovation
2013 - University of Alicante | Investigaciones Turísticas
Lidia Dalfino, Monica Stufano, Davide Fiore Bavaro, Lucia Diella, Alessandra Belati, Stefania Stolfa, Federica Romanelli, Luigi Ronga, Rosa Di Mussi, Francesco Murgolo, Daniela Loconsole, Maria Chironna, Adriana Mosca, Maria Teresa Montagna, Annalisa Saracino, Salvatore Grasso,
Evidence-based, standard antibiotic therapy for ventilator-associated pneumonia (VAP) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) is a relevant unmet clinical need in the intensive care unit (ICU). We aimed to evaluate the effectiveness of first-line therapy with old and novel CRAB active antibiotics in monomicrobial VAP caused by CRAB. A prospective, observational study was performed in a mixed non-COVID-19 ICU. The primary outcome measure was clinical failure upon first-line targeted ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2023 - Multidisciplinary Digital Publishing Institute | Antibiotics
Alberto Enrico Maraolo, Federica Licciardi, Ivan Gentile, Annalisa Saracino, Alessandra Belati, Davide Fiore Bavaro,
(SM) represents a challenging pathogen due to its resistance profile. A systematic review of the available evidence was conducted to evaluate the best treatment of SM infections to date, focusing on trimethoprim/sulfamethoxazole (TMP/SMX), fluoroquinolones (FQs), and tetracycline derivatives (TDs).
Tópico(s): Infections and bacterial resistance
2023 - Multidisciplinary Digital Publishing Institute | Antibiotics
Davide Fiore Bavaro, Roberta Papagni, Alessandra Belati, Lucia Diella, Antonio De Luca, Gaetano Brindicci, Nicolò De Gennaro, Francesco Di Gennaro, Federica Romanelli, Stefania Stolfa, Luigi Ronga, Adriana Mosca, Francesco Pomarico, Maria Dell’Aera, Monica Stufano, Lidia Dalfino, Salvatore Grasso, Annalisa Saracino,
Bloodstream infections (BSI) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) are associated with high mortality with limited treatment. The aim of this study is to compare effectiveness and safety of colistin-based versus cefiderocol-based therapies for CRAB-BSI.This is a retrospective observational study enrolling patients with monomicrobial CRAB-BSIs treated with colistin or cefiderocol from 1 January 2020, to 31 December 2022. The 30-day all-cause mortality rate was the primary outcome. ...
Tópico(s): Pneumonia and Respiratory Infections
2023 - Adis, Springer Healthcare | Infectious Diseases and Therapy
Roberta Papagni, Roberta Novara, Maria Letizia Minardi, Luisa Frallonardo, Gianfranco Giorgio Panico, Elisabetta Pallara, Sergio Cotugno, Tommaso Ascoli Bartoli, Giacomo Guido, Elda De Vita, Aurelia Ricciardi, Valentina Totaro, Michele Camporeale, Francesco Vladimiro Segala, Davide Fiore Bavaro, Giulia Patti, Gaetano Brindicci, Carmen Pellegrino, Michele Mariani, Giovanni Putoto, Loredana Sarmati, Chiara Castellani, Annalisa Saracino, Francesco Di Gennaro, Emanuele Nicastri,
According to both definitions of US Centers for Disease Control and Prevention and World Health Organization, Neglected Tropical Diseases (NTDs) are a group of preventable and treatable parasitic, viral, and bacterial diseases that affect more than one billion people globally. They generally afflict the more indigent patients of the world and historically have not received as much attention as other diseases. NTDs tend to thrive in low-income regions, where water quality, sanitation and access to ...
Tópico(s): Parasites and Host Interactions
2023 - Frontiers Media | Frontiers in Tropical Diseases
Eleonora De Matteis, Federico De Santis, Raffaele Ornello, Bruno Censori, Valentina Puglisi, Luisa Vinciguerra, Alessia Giossi, Pietro Di Viesti, Vincenzo Inchingolo, Giovanni Matteo Fratta, Marina Diomedi, Maria Rosaria Bagnato, Silvia Cenciarelli, Chiara Bedetti, Chiara Padiglioni, Tiziana Tassinari, Valentina Saia, Alessandro Russo, Marco Petruzzellis, Domenico Maria Mezzapesa, Martina Caccamo, Giuseppe Rinaldi, Alessandra Bavaro, Maurizio Paciaroni, Maria Giulia Mosconi, Matteo Foschi, Pietro Querzani, Francesco Muscia, Serena Gallo Cassarino, Paolo Candelaresi, Antonio De Mase, Maria Guarino, Letizia Maria Cupini, Enzo Sanzaro, Andrea Zini, Salvatore La Spada, Carmela Palmieri, Federica Nicoletta Sepe, Simone Beretta, Cristina Paci, Emanuele Alessandro Caggia, Maria Vittoria De Angelis, Laura Bonanni, Gino Volpi, Rossana Tassi, Francesca Pistoia, Umberto Scoditti, Agnese Tonon, Giovanna Viticchi, Giampietro Ruzza, Patrizia Nencini, Anna Cavallini, Danilo Toni, Stefano Ricci, Simona Sacco, Maria Cristina Acciarri, Chiara Alessi, Stefania Martina Angelocola, Paola Ajdinaj, Leonardo Barbarini, Valentina Barone, Maraia Cristina Baruffi, Maria Chiara Bassi, Mario Beccia, Simone Bellavia, Leonardo Biscetti, Novella Bonaffini, Laura Bolamperti, Maria Roberta Bongioanni, Marianna Brienza, Gian Luca Bruzzone, Valentina Cameriere, Alessandro Campagnaro, Roberto Cappellani, Manuel Cappellari, Luigi Caputi, Patrizio Cardinali, Lorenzo Coppo, Antonella Boni, Ivo Giuseppe De Franco, Cristina De Luca, Susanna Diamanti, Francesco Di Blasio, Caterina Di Carmine, Filomena Di Lisi, Anna di Giovanni, Claudia Faini, Carlo Ferrarese, Thomas Fleetwood, Alberto Fortini, Giovanni Frisullo, Debora Galotto, Antonio Genovese, Luana Gentile, Paolo Invernizzi, Sara La Starza, Federica Letteri, Giovanni Manobianca, Marina Mannino, Michela Marcon, Maela Masato, Federico Mazzacane, E. Menegazzo, C. Menichetti, Daniela C. Mónaco, Federica Naldi, Serena Nannucci, C Occhipinti, Daniele Orsucci, Silvia Paolucci, Francesco Passarelli, Giulio Papiri, Giuseppe Pelliccioni, Francesco Perini, Vincenza Pinto, Eleonora Potente, Emanuele Puca, Maria Chiara Ricciardi, Cinzia Roberti, Michele Romoli, Francesca Rondelli, Eugenia Rota, Monia Russo, Elisa Sacchini, Alessandra Sanna, Gaspare Scaglione, Andrea Scalvini, Irene Scala, Ciro Scarpato, Giovanna Servillo, Eleonora Sgarlata, Mauro Silvestrini, Marco Simonetto, Emanuele Spina, Roberto Tarletti, Valeria Terruso, Pierluigi Tocco, Laura Tudisco, Gloria Valcamonica, Martina Valente, Marco Vista, Antonio Zito, Cecilia Zivelonghi,
Randomized controlled trials (RCTs) proved that short-term (21-90 days) dual antiplatelet therapy (DAPT) reduces the risk of early ischemic recurrences after a noncardioembolic minor stroke or high-risk transient ischemic attack (TIA) without substantially increasing the hemorrhagic risk. We aimed at understanding whether and how real-world use of DAPT differs from RCTs.READAPT (Real-Life Study on Short-Term Dual Antiplatelet Treatment in Patients With Ischemic Stroke or TIA) is a prospective cohort ...
Tópico(s): Peripheral Artery Disease Management
2023 - Lippincott Williams & Wilkins | Stroke
Nicola Veronese, Francesco Vladimiro Segala, Luca Carruba, Anna La Carrubba, Francesco Pollicino, Giusi Di Franco, Giacomo Guido, M Cormio, Alessia Lugli, Laura De Santis, Vittorio Guerra, Martino Pepe, Rocco Tritto, Marco Matteo Ciccone, Davide Fiore Bavaro, Gaetano Brindicci, Pasquale Mansueto, Lydia Giannitrapani, Francesco Di Gennaro, Mario Barbagallo, Annalisa Saracino,
Abstract In respiratory infections, anemia is both a consequence of acute inflammation and a predictor of poor clinical outcomes. There are few studies investigating the role of anemia in COVID-19, suggesting a potential role in predicting disease severity. In this study, we aimed to assess the association between the presence of anemia at admission and incidence of severe disease and death in patients hospitalized for COVID-19. Data from all adult patients admitted for COVID-19 in University Hospital “ ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2023 - Nature Portfolio | Scientific Reports
Francesco Di Gennaro, Claudia Marotta, Lucy Ramirez, Hamilton Cardoso, Chivite Alamo, Vasco Cinturao, Davide Fiore Bavaro, Dezi Cornelia Mahotas, Marzia Lazzari, Chenene Fernando, Natalia Chimundi, Andrea Atzori, Izilda Chaguruca, Francesca Tognon, Helga Guambe Dos Anjos, Giovanna De Meneghi, Mireille Tribie, Fabrizia Del Greco, Edson Namarime, Edoardo Occa, Giovanni Putoto, Anton Pozniak, Annalisa Saracino,
Adolescent mental health (MH) is a significant global health concern, which is extremely relevant when referring to adolescents and youth living with HIV (AYHIV). In Mozambique, ∼52% of the population is 10 for women, [adjusting odds ratio (AOR): 1.46, 95% confidence interval (CI): 1.01-2.10], for workers (AOR: 2.18, 95% CI: 1.12-4.23) and people living with HIV (AOR: 1.78, 95% CI: 1.25-2.54). Higher values of CAGE (≥2) and PTSD (≥3) seemed to be associated only with HIV-positive status (AOR: 4.87, 95% CI: 3. ...
Tópico(s): Adolescent and Pediatric Healthcare
2022 - Mary Ann Liebert, Inc. | AIDS Patient Care and STDs
Eugenio Milano, Aurelia Ricciardi, Raffaella Casciaro, Elisabetta Pallara, Elda De Vita, Davide Fiore Bavaro, Angela Maria Vittoria Larocca, Pasquale Stefanizzi, Silvio Tafuri, Annalisa Saracino,
In March, people living with HIV infection (PLWH) were included in the risk category of fragile people for severe COVID-19 receiving priority access to vaccination with BNT162b2 vaccine. The aim of the study was to evaluate the immunogenicity and safety of the two doses regimen. The antibodies titer for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) was evaluated after 21 days since the first administration (Time 1), 1 (Time 2), and 3 (Time 3) months post-vaccination. Information ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - Wiley | Journal of Medical Virology
Francesco Di Gennaro, Nicola Veronese, Claudia Marotta, Jae Il Shin, Ai Koyanagi, Andrea Silenzi, Mario Antunes, Annalisa Saracino, Davide Fiore Bavaro, Pınar Soysal, Francesco Vladimiro Segala, Laurie T. Butler, Eugenio Milano, Mario Barbagallo, Yvonne Barnett, Christopher N. Parris, Emanuele Nicastri, Damiano Pizzol, Lee Smith,
Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against ...
Tópico(s): Herpesvirus Infections and Treatments
2022 - Multidisciplinary Digital Publishing Institute | Microorganisms
Nicola Veronese, Roberta Bonica, Sergio Cotugno, Ottavia Tulone, Michele Camporeale, Lee Smith, Mike Trott, Olivier Bruyère, Luigi Mirarchi, Giuseppina Rizzo, Davide Fiore Bavaro, Mario Barbagallo, Ligia J. Domínguez, Claudia Marotta, Andrea Silenzi, Emanuele Nicastri, Annalisa Saracino, Francesco Di Gennaro,
Although the understanding of several aspects of long COVID-19 syndrome is increasing, there is limited literature regarding the treatment of these signs and symptoms. The aim of our systematic review was to understand which therapies have proved effective against the symptoms of long COVID-19.
Tópico(s): COVID-19 and Mental Health
2022 - Multidisciplinary Digital Publishing Institute | Viruses
David Jiménez, Parth Rali, Kevin C. Doerschug,
... patients with COVID-19.1Scardapane A. Villani L. Bavaro D.F. et al.Pulmonary artery filling defects ...
Tópico(s): COVID-19 and healthcare impacts
2022 - Elsevier BV | CHEST Journal
Roberta Papagni, Carmen Pellegrino, Francesco Di Gennaro, Giulia Patti, Aurelia Ricciardi, Roberta Novara, Sergio Cotugno, Maria Musso, Giacomo Guido, Luigi Ronga, Stefania Stolfa, Davide Fiore Bavaro, Federica Romanelli, Valentina Totaro, Rossana Lattanzio, Giuseppina De Iaco, Fabrizio Palmieri, Annalisa Saracino, Gina Gualano,
Vitamin D plays a crucial role in many infectious diseases, such as tuberculosis (TB), that remains one of the world's top infectious killers with 1.5 million deaths from TB in 2021. Vitamin D suppresses the replication of Mycobacterium tuberculosis in vitro and showed a promising role in TB management as a result of its connection with oxidative balance. Our review encourages the possible in vivo benefit of a joint administration with other vitamins, such as vitamin A, which share a known antimycobacterial ...
Tópico(s): Tuberculosis Research and Epidemiology
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Giacomo Rossino, Marina Simona Robescu, Ester Licastro, Claudia Tedesco, Ilaria Martello, Luciana Maffei, Gregory Vincenti, Teodora Bavaro, Simona Collina,
Abstract Over the last decades, biocatalysis has achieved growing interest thanks to its potential to enable high efficiency, high yield, and eco‐friendly processes aimed at the production of pharmacologically relevant compounds. Particularly, biocatalysis proved an effective and potent tool in the preparation of chiral molecules, and the recent innovations of biotechnologies and nanotechnologies open up a new era of further developments in this field. Different strategies are now available for ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2022 - Wiley | Chirality
Wieneke Dijk, Caterina Villa, Sara Benedé, Εmilia Vassilopoulou, Isabel Mafra, María Garrido‐Arandia, Mónica Martínez‐Blanco, Grégory Bouchaud, Tamara Hoppenbrouwers, Simona L. Bavaro, Linda Giblin, Karen Knipping, Ana Castro, Susana Delgado, Joana Costa, Shanna Bastiaan‐Net,
Abstract New types of protein sources will enter our diet in a near future, reinforcing the need for a straightforward in vitro (cell‐based) screening model to test and predict the safety of these novel proteins, in particular their potential risk for de novo allergic sensitization. The Adverse Outcome Pathway (AOP) for allergen sensitization describes the current knowledge of key events underlying the complex cellular interactions that proceed allergic food sensitization. Currently, there is no consensus ...
Tópico(s): Microbial Inactivation Methods
2022 - Wiley | Comprehensive Reviews in Food Science and Food Safety
Francesco Di Gennaro, Alessandra Belati, Ottavia Tulone, Lucia Diella, Davide Fiore Bavaro, Roberta Bonica, Vincenzo Genna, Lee Smith, Mike Trott, Olivier Bruyère, Luigi Mirarchi, Claudia Cusumano, Ligia J. Domínguez, Annalisa Saracino, Nicola Veronese, Mario Barbagallo,
The long-term consequences of the coronavirus disease 19 (COVID-19) are likely to be frequent but results hitherto are inconclusive. Therefore, we aimed to define the incidence of long-term COVID signs and symptoms as defined by the World Health Organization, using a systematic review and meta-analysis of observational studies. A systematic search in several databases was carried out up to 12 January 2022 for observational studies reporting the cumulative incidence of long COVID signs and symptoms ...
Tópico(s): COVID-19 and Mental Health
2022 - Springer Science+Business Media | Internal and Emergency Medicine
Alessandra Belati, Davide Fiore Bavaro, Lucia Diella, Nicolò De Gennaro, Francesco Di Gennaro, Annalisa Saracino,
Objectives: The aim of this study was to describe our experience of a combination treatment including meropenem/vaborbactam (M/V) plus aztreonam (ATM) for bloodstream infections (BSIs) due to ceftazidime/avibactam-resistant Klebsiella pneumoniae (CAZ/AVI-R-Kp), for which gene typing was not available at the time the blood culture (BC) results were obtained. Methods: Between 20 July and 22 August 2021, in our hospital laboratory, the molecular test for carbapenemase gene typing was not available. All ...
Tópico(s): Infections and bacterial resistance
2022 - Multidisciplinary Digital Publishing Institute | Antibiotics
Angela De Palma, Mirko Girolamo Cantatore, Francesco Di Gennaro, Francesca Del Signore, Teodora Panza, Debora Brascia, Giulia De Iaco, Doroty Sampietro, Rosatea Quercia, Marcella Genualdo, Ondina Pizzuto, Giuseppe Garofalo, Fabio Signorile, Davide Fiore Bavaro, Gaetano Brindicci, Nicolò De Gennaro, Annalisa Saracino, Nicola Quaranta, Gianfranco Favia, Giuseppe Marulli,
Descending necrotizing mediastinitis (DNM) is an acute, rare, severe condition with high mortality, but the optimal management protocol is still controversial. We retrospectively analyzed the results of multidisciplinary management in patients treated for DNM at our center over the last twenty years. Fifteen male patients, mean age 49.07 ± 14.92 years, were treated: 9 with cervico-pharyngeal etiopathogenesis, 3 peri-tonsillar/tonsillar, 2 odontogenic, 1 post-surgical; 6 with DNM type I, 6 with type ...
Tópico(s): Infectious Diseases and Tuberculosis
2022 - Multidisciplinary Digital Publishing Institute | Antibiotics
Nicole Bavaro, Deborah Gakpo, Anisha Mittal, Jillian C. Bensko, Tanya M. Laidlaw, Kathleen M. Buchheit,
Aspirin-exacerbated respiratory disease (AERD), the triad of asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and respiratory reactions to cyclooxygenase-1 inhibitors, is characterized by difficult-to-treat upper and lower respiratory symptoms. It is a type 2–mediated inflammatory disease marked by blood and tissue eosinophilia, dysregulated cysteinyl leukotriene production, and mast cell activation.1 Nasal polyposis in AERD is often severe and refractory to standard-of-care management including ...
Tópico(s): Respiratory and Cough-Related Research
2021 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
Giulia Patti, Carmen Pellegrino, Aurelia Ricciardi, Roberta Novara, Sergio Cotugno, Roberta Papagni, Giacomo Guido, Valentina Totaro, Giuseppina De Iaco, Federica Romanelli, Stefania Stolfa, Maria Letizia Minardi, Luigi Ronga, Ilenia Fato, Rossana Lattanzio, Davide Fiore Bavaro, Gina Gualano, Loredana Sarmati, Annalisa Saracino, Fabrizio Palmieri, Francesco Di Gennaro,
(1) Background: Tuberculosis (TB) is one of the world’s top infectious killers, in fact every year 10 million people fall ill with TB and 1.5 million people die from TB. Vitamins have an important role in vital functions, due to their anti-oxidant, pro-oxidant, anti-inflammatory effects and to metabolic functions. The aim of this review is to discuss and summarize the evidence and still open questions regarding vitamin supplementation as a prophylactic measure in those who are at high risk of Mycobacterium ...
Tópico(s): Vitamin D Research Studies
2021 - Multidisciplinary Digital Publishing Institute | Antibiotics
Anum Minhas, Nisha A. Gilotra, Erin Goerlich, Thomas S. Metkus, Brian T. Garibaldi, Garima Sharma, Nicole Bavaro, Susan Phillip, Erin D. Michos, Allison G. Hays,
Background: Although troponin elevation is common in COVID-19, the extent of myocardial dysfunction and its contributors to dysfunction are less well-characterized. We aimed to determine the prevalence of subclinical myocardial dysfunction and its association with mortality using speckle tracking echocardiography (STE), specifically global longitudinal strain (GLS) and myocardial work efficiency (MWE). We also tested the hypothesis that reduced myocardial function was associated with increased systemic ...
Tópico(s): Cardiovascular Disease and Adiposity
2021 - Frontiers Media | Frontiers in Cardiovascular Medicine
Francesco Vladimiro Segala, Davide Fiore Bavaro, Francesco Di Gennaro, Federica Salvati, Claudia Marotta, Annalisa Saracino, Rita Murri, Massimo Fantoni,
Antimicrobial resistance is an urgent threat to public health and global development; in this scenario, the SARS-CoV2 pandemic has caused a major disruption of healthcare systems and practices. A narrative review was conducted on articles focusing on the impact of COVID-19 on multidrug-resistant gram-negative, gram-positive bacteria, and fungi. We found that, worldwide, multiple studies reported an unexpected high incidence of infections due to methicillin-resistant
Tópico(s): Nosocomial Infections in ICU
2021 - Multidisciplinary Digital Publishing Institute | Viruses
Davide Fiore Bavaro, Alessandra Belati, Lucia Diella, Monica Stufano, Federica Romanelli, Luca Scalone, Stefania Stolfa, Luigi Ronga, Leonarda Maurmo, Maria Dell’Aera, Adriana Mosca, Lidia Dalfino, Salvatore Grasso, Annalisa Saracino,
Cefiderocol is a new cephalosporin displaying against extensively resistant (XDR) Gram-negative bacteria. We report our experience with cefiderocol-based combination therapies as “rescue” treatments in immunocompromised or critically ill patients or in patients with post-surgical infections who had failed previous regimens. A total of 13 patients were treated from 1 September 2020 to 31 March 2021. In total, 5/13 (38%) patients were classified as critically ill, due to severe COVID-19 lung failure; ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2021 - Multidisciplinary Digital Publishing Institute | Antibiotics
Mariacristina Poliseno, Davide Fiore Bavaro, Gaetano Brindicci, Giovanni Luzzi, D Carretta, Antonio Spinarelli, Raffaella Messina, Maria Paola Miolla, Teresa Immacolata Achille, Maria Rosaria Dibartolomeo, Maria Dell’Aera, Annalisa Saracino, Gioacchino Angarano, Stefano Favale, Carlo D’Agostino, Biagio Moretti, Francesco Signorelli, Camilla Taglietti, Sergio Carbonara,
The study aimed to evaluate the impact of dalbavancin therapy on both hospital length-of-stay (LOS) and treatment-related costs, as well as to describe the clinical outcome, in a retrospective cohort of patients with diverse Gram-positive bacterial infections, hospitalized in different specialty Units. From July 2017 to July 2019, clinical and sociodemographic data were collected for all hospitalized patients switched to dalbavancin for the treatment of Gram-positive infections. LOS and treatment- ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2021 - Adis, Springer Healthcare | Clinical Drug Investigation
Joana Costa, Caterina Villa, Kitty Verhoeckx, Tanja Ćirković Veličković, Denise Schrama, Paola Roncada, Pedro M. Rodrigues, Cristian Piras, Laura Martín‐Pedraza, Linda Monaci, Elena Molina, Gabriel Mazzucchelli, Isabel Mafra, Roberta Lupi, Daniel Lozano‐Ojalvo, Colette Larré, Julia Klueber, É. Gelencsér, Cristina Bueno, Araceli Díaz‐Perales, Sara Benedé, Simona L. Bavaro, Annette Kuehn, Karin Hoffmann‐Sommergruber, Thomas Holzhauser,
Key determinants for the development of an allergic response to an otherwise ‘harmless’ food protein involve different factors like the predisposition of the individual, the timing, the dose, the route of exposure, the intrinsic properties of the allergen, the food matrix (e.g. lipids) and the allergen modification by food processing. Various physicochemical parameters can have an impact on the allergenicity of animal proteins. Following our previous review on how physicochemical parameters shape ...
Tópico(s): Allergic Rhinitis and Sensitization
2021 - Springer Nature | Clinical Reviews in Allergy & Immunology
Simona L. Bavaro, Gianfranco Mamone, Gianluca Picariello, Michael Callanan, Yihong Chen, André Brodkorb, Linda Giblin,
Infant Milk Formula (IMF) is designed as a breastmilk substitute to satisfy the nutritional requirements during the first months of life. This study investigates the effects of two IMF processing technologies on cow milk protein digestion using an infant static in vitro gastrointestinal model. The degree of protein hydrolysis at the end of the gastric phase was 3.7-fold higher for IMF produced by high temperature (IMF-HT), compared to IMF produced by cascade membrane filtration (IMF-CMF), as assessed ...
Tópico(s): Infant Nutrition and Health
2021 - Elsevier BV | Food Chemistry