Emma Du, James F. Fleming, Shui-Long Wang, Gary M. Spitsen, Roger J. Davis,
... confluence in the absence of antibiotics unless indicated. B53 cells (CHO cells expressing apoB53 (18Du E. Kurth ... apoB). Resistant cells were characterized as described below. B53 cells were co-transfected with a pcDNA3 plasmid ... plasmid at a 1:19 molar ratio into B53 cells. Cells were selected in 500 μg/ml ... using the ECL detection kit (Amersham Pharmacia Biotech). B53 and JF7 cells were grown to 80% confluence ... when apoB53 is stably expressed in CHO cells (B53 cells), it is rapidly degraded, producing an N- ...
Tópico(s): Lipid metabolism and biosynthesis
1999 - Elsevier BV | Journal of Biological Chemistry
Patrick N. Bisimwa, Juliette R. Ongus, Lucilla Steinaa, Espoir Basengere Bisimwa, Edwina Bochere, Eunice Machuka, Jean-Baka Domelevo Entfellner, Edward Okoth, Roger Pellé,
... DNA. The assembled Uvira ASFV genome, termed Uvira B53, was 180,916 bp long that could be ... relationship with selected representative genomes clustered the Uvira B53 strain together with ASFV genotype X reported to ... 168 ORFs were fully conserved in the Uvira B53. The other 38 ORFs were divergent mainly due ... and Ken05/Tk1 were absent from the Uvira B53 genome including three members of MGF 360, four ... end of the genome was truncated in Uvira B53. Moreover, ORFs DP96R and p285L were also absent in the Uvira B53 genome. In contrast, the ORF MGF 110-5L ...
Tópico(s): T-cell and Retrovirus Studies
2021 - BioMed Central | Virology Journal
Franziska L. Lederer, Ulrike Weinert, Tobias Günther, Johannes Raff, Stephan Weiß, Katrin Pollmann,
Lysinibacillus sphaericus JG-B53 was isolated from the uranium mining waste pile Haberland near Johanngeorgenstadt, Germany. Previous studies have shown that many bacteria ... of the S-layer of L. sphaericus JG-B53, which possesses outstanding recrystallization and metal-binding properties. ... encoded in the genome of L. sphaericus JG-B53 were identified using next-generation sequencing technology followed ... bioinformatic analyses. The genome of L. sphaericus JG-B53 encodes at least eight putative S-layer protein ...
Tópico(s): Mine drainage and remediation techniques
2013 - Microbiology Society | Microbiology
Allen J. Norin, Rachelle Mendoza, Michael Augenbraun, Ballabh Das,
... as the primary end-point. One HLA allele, B53, appeared to be more prevalent in the hospitalized ... percent of positive subjects, 24.5). The percent B53 positive in non-hospitalized COVID-19 patients was ... greater deaths (73 percent) were observed in HLA B53 positive hospitalized COVID-19 patients compared to hospitalized COVID-19 patients who were B53 negative (40 percent). Multi-variate analysis indicated that HLA B53 positive Black hospitalized COVID-19 patients were at ... death than Black COVID-19 patients who were B53 negative. Consideration for accelerated vaccination and treatment should ...
Tópico(s): Diabetes and associated disorders
2021 - Elsevier BV | Human Immunology
Ambika Mathur, D Kamat, Brian G. Van Ness, Richard G. Lynch,
... bearing ascitic tumors of the IgE-secreting hybridoma B53 (epsilon, kappa, anti-dinitrophenyl) developed large numbers of ... decline in serum IgE levels in mice with B53 tumors and to identify host factors that might ... involved in this process. We observed that ascitic B53 cells recovered at increasing time points from BALB/ ... heavy chain gene expression did not occur when B53 tumors were passaged in nu+/nu+ mice or ... by the earlier and more pronounced inhibition of B53 IgE in mice infused with Fc epsilon R(+) ...
Tópico(s): Synthesis and Biological Evaluation
1987 - American Association of Immunologists | The Journal of Immunology
Xiaolong Li, Nishant K. Singh, David R. Collins, Robert Ng, Angela Zhang, Pedro A. Lamothe, Peter Shahinian, Shutong Xu, Kemin Tan, Alicja Piechocka‐Trocha, Jonathan M. Urbach, Jeffrey K. Weber, Gaurav D. Gaiha, Overbeck C. Takou Mbah, Tien Huynh, Sophia Cheever, James Chen, Michael E. Birnbaum, Ruhong Zhou, Bruce D. Walker, Jia‐Huai Wang,
... disease-protective HLA-B57 and disease-neutral HLA-B53. Despite robust targeting of QW9 in persons expressing ... S3T is consistently reduced when presented by HLA-B53 but not by HLA-B57. Crystal structures show ... S3T-HLA by both alleles. The TCR-QW9-B53 ternary complex structure manifests how the QW9-B53 can elicit effective CTLs and suggests sterically hindered cross-recognition by QW9_S3T-B53. We observe populations of cross-reactive TCRs for B57, but not B53 and also find greater peptide-HLA stability for ...
Tópico(s): T-cell and B-cell Immunology
2023 - Nature Portfolio | Nature Communications
Keats Nelms, Brian G. Van Ness, Richard G. Lynch, Ambika Mathur,
... vitro co-culture of IgE-secreting hybridoma cells (B53) with spleen cells harvested from mice with established B53 tumours results in a specific, T cell-dependent suppression of ϵ-chain expression in the B53 cells. The role of immunoglobulin enhancers in the suppression of IgE synthesis in B53 cells was examined by transfecting B53 cells with CAT expression vectors containing the immunoglobulin ... T cell-dependent suppression of IgE synthesis in B53 cells correlates with a specific inactivation of the ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
1991 - Elsevier BV | Molecular Immunology
Koichi Hattori, Takao Hirano, Hiroaki Miyajima, Norifumi Yamakawa, Shoji Ikeda, Kiyoshi Yoshino, Masatoshi Tateno, Kazuo Oshimi, Nobuhiko Kayagaki, Hideo Yagita∥, Ko Okumura,
... mice that had been inoculated with IgE‐producing B53 hybridoma cells of BALB/c origin as a ... R7785 without BMS significantly prolonged the survival of B53‐inoculated CBF1 mice by inhibiting the infiltration of B53 cells into the liver and spleen. Transplantation of ... recipients due to acute GVHD while efficiently eliminating B53 cells. Administration of KB‐R7785 along with B6 BMS resulted in a 50% survival of B53‐inoculated CBF1 mice over 50 d without histological manifestations of acute GVHD or residual B53 cells. These results indicate the beneficial effects of ...
Tópico(s): Multiple Myeloma Research and Treatments
1999 - Wiley | British Journal of Haematology
Christian Zwiener, Michael U. Kumke, Gudrun Abbt‐Braun, F. H. Frimel,
... isolated from two contaminated groundwater samples (B22 and B53) from a site of a former gas facility. ... collected from the contamination plume whereas the sample B53 FA was collected downstream. Distinct differences were exhibited ... as the HIC and SEC chromatograms of the B53 FA sample resemble those of the FA fraction ... Charakterisierung Von den zwei kontaminierten Grundwasserproben B22 und B53 eines ehemaligen Gaswerksgeländes wurden Huminstoffe (HS) isoliert. Dabei ... wobei B22 FA direkt aus der Schadstoffahne und B53 FA aus dem Abstrombereich stammt. Berücksichtigt man die ...
Tópico(s): Marine and coastal ecosystems
1999 - Wiley | Acta hydrochimica et hydrobiologica
Michael Aidoo, Ajit Lalvani, Sarah C. Gilbert, Jiang Hu, Pierre Daubersies, N. Hurt, Hilton Whittle, Pierre Druihle, Adrian V. S. Hill,
... from several preerythrocytic antigens. The association of HLA-B53 with resistance to severe malaria in West Africa ... has been shown to be recognized by HLA-B53-specific cytotoxic T lymphocytes (CTL), but HLA-B53 epitopes were not found in four other antigens. ... in it a new epitope restricted by HLA-B53. Several CTL epitopes restricted by other class I ...
Tópico(s): Hepatitis C virus research
2000 - American Society for Microbiology | Infection and Immunity
Koichi Hattori, T Hirano, Kazuo Oshimi, Hideo Yagita∥, Ko Okumura,
... BMS). significantly prolonged the survival of IgE-producing B53 hybridoma cell-inoculated (C57BL/6 x BALB/c) F1 (CBF1) mice by inhibiting the infiltration of B53 cells into the liver and spleen. Transplantation of ... recipients due to acute GVHD while efficiently eliminating B53 cells. Administration of KB-R7785 along with B6 BMS resulted in 50% survival of B53-inoculated CBF1 mice over 50 days without histological manifestations of acute GVHD or residual B53 cells. These results suggest that KB-R7785 could ...
Tópico(s): Acute Myeloid Leukemia Research
2000 - Taylor & Francis | Leukemia & lymphoma/Leukemia and lymphoma
Ambika Mathur, Brian G. Van Ness, Richard G. Lynch,
... injected i.p. with the IgE-secreting hybridomas B53 (epsilon, kappa anti-DNP), SE1.3 (epsilon, kappa, ... IgE (Fc epsilon R+ T lymphocytes). Mice with B53 or SE1.3 hybridomas initially developed high concentrations ... with spleen cells harvested from mice with established B53 tumors was used to investigate the mechanisms involved ... when cocultured with spleen cells from mice with B53 tumors.
Tópico(s): Immune Cell Function and Interaction
1990 - American Association of Immunologists | The Journal of Immunology
Sergio Rivera P., Georgina Márquez, Ana María Cipriani, Manzur Hassanhi, Carmen Villalobos, Alba Fuenmayor, Maribel Chávez, Milagros Montiel,
... associated to the ESRD were: HLA-B38, B51, B53 and B62. Negatively associated antigens were: HLA-A9, ... haplotypes positively associated were: HLA-A2-B51, A2-B53, A23-B38 and A68-B38. The negatively associated ... I asociados a ESRD fueron: HLA-B38, B51, B53, B62; y los asociados negativamente resultaron HLA-A9, ... haplotipos asociados positivamente fueron: HLA-A2-B51, A2-B53, A23-B38 y A68-B38. Los haplotipos asociados ...
Tópico(s): Diabetes and associated disorders
2012 - Elsevier BV | Inmunología
Stanley D. Dunn, Jennifer Chandler,
... Leu156 and Tyr24–Leu156, respectively;b34–156 and b53–156, forms of the cytoplasmic domain of the ... of the b cytoplasmic domain,b34–156 or b53–156, have been described previously (40McLachlin D.T. ... mixtures of the soluble b domainsb34–156 or b53–156 with δ sedimented slightly more rapidly than ... and tyrosine residues present in b34–156 and b53–156 were added at their N termini during ...
Tópico(s): Pediatric Hepatobiliary Diseases and Treatments
1998 - Elsevier BV | Journal of Biological Chemistry
Zemin Yao, B D Blackhart, MacRae F. Linton, Stacy Taylor, Stephen G. Young, Brian J. McCarthy,
... apoB proteins (apoB18, -B23, -B28, -B31, -B48, and -B53). Immunoblotting of apoB proteins secreted into the culture ... whereas particles containing apoB28, -B31, -B37, -B48, and -B53 exhibited progressive decreases in density. The density distribution ... nondenaturing gel electrophoresis, apoB28, -B31, -B37, -B48, and -B53 formed their own discrete particles, and there was ...
Tópico(s): Peroxisome Proliferator-Activated Receptors
1991 - Elsevier BV | Journal of Biological Chemistry
F Gotch, Steve McAdam, C.E.M. Allsopp, Awen Gallimore, John Elvin, Marie Paule Kiény, AV Hill, Andrew J. McMichael, H. Whittle,
... HIV2 gag that is recognized by CD8+ HLA-B53 CTL using an amino acid sequence motif predicted from analysis of endogenous peptides eluted from HLA-B53 molecules. This peptide, from an HIV2/SIV conserved ... of SIV or infected with SIV virus. HLA-B53-restricted, HIV2 gag-specific CTL did not recognize ...
Tópico(s): vaccines and immunoinformatics approaches
1993 - American Association of Immunologists | The Journal of Immunology
Kathrine J. Smith, Scott W. Reid, Karl Harlos, Andrew J. McMichael, David I. Stuart, John I. Bell, E. Yvonne Jones,
... of the human MHC class I molecule HLA-B53 complexed to two nonameric peptide epitopes (from the ... HLA-B alleles. Relative to other alleles, the B53 peptide-binding groove is widened by a significant ( ...
Tópico(s): T-cell and B-cell Immunology
1996 - Cell Press | Immunity
E R Heise, Carolina H. Manning, Leroy R. Thacker,
... reduced risk of sensitization, and five allelotypes (B42,B53; A 10,19,36) were associated with an ... to be sensitized per allelotype. Recipients with B42, B53 or A36 were at increased risk of preformed ... A1: DR3-B42-A30; DR6-B42-A30; DR11-B53-A30 (RR range 2.76-1.48) with ...
Tópico(s): Vascular anomalies and interventions
2001 - Wiley | Clinical Transplantation
Jesús Yagüe, Jesús Vázquez, José A. Łópez de Castro,
... Pro2 and nonpolar C‐terminal residues, including HLA‐B53, an antigen associated with protection against severe malaria. ... peptidic anchors suggests that B*3910 and HLA‐B53 may bind common peptides.
Tópico(s): Immunotherapy and Immune Responses
1998 - Wiley | Tissue Antigens
Matthew Revington, Derek T. McLachlin, Gary S. Shaw, Stanley D. Dunn,
... 0.062.13 ± 0.111.36 ± 0.04 b53–15611,8982.02 ± 0.072.40 ± 0.021. ... 011.08 ± 0.01N- and C-terminal truncations b53–1228,3651.96 ± 0.051.89 ± 0.031.25 ± 0.03 b53–122, pH 5.08,3651.95 ± 0.021. ...
Tópico(s): Advanced Electron Microscopy Techniques and Applications
1999 - Elsevier BV | Journal of Biological Chemistry
... for Bacillus sp.224 B4 and Bac.subtilis B53 for 48-72 h.When the buckwheat was ... fermented with Bifidobacterium breve BV-B, Bacillus subtilis B53, and Lactobacillus buchneri, the contents of rutin and ... fermented by Bacillus sp.224 B4, Bac.subtilis B53, Bac.subtilis KCCM11315, Bif.animalis, and Bif.breve ...
Tópico(s): GABA and Rice Research
2017 - OMICS Publishing Group | Fermentation Technology
Priscillar Mumo Mutungi, Vitalis W. Wekesa, Justus Onguso, Erustus Kanga, Steve B. S. Baleba, Hamadi Boga,
... 5 M NaCl; three isolates (B23, B19, and B53) produced indole acetic acid (IAA) and only one ... solubilize phosphate on Pikovskaya agar. Isolates, B19 and B53 exhibited more than 50% of mycelial inhibition in ... bean seedlings by the bacterial endophytes, B19 and B53 resulted in the biocontrol of F. solani in ...
Tópico(s): Plant Pathogenic Bacteria Studies
2022 - Frontiers Media | Frontiers in Plant Science
Dan Li, Xiaodong Bao, Jinping Pang, Xueping Hu, Longling Wang, Jiajia Wang, Zhaoxu Yang, Lei Xu, Siyu Wang, Qinjie Weng, Sunliang Cui, Tingjun Hou,
... by structural optimization of HP-19. Therein, compound B53 exhibits the best transrepression activity (IC50 NF-κB = ... 005 ± 0.001 μM) and no transactivation activity. B53 can efficiently reduce the expression of inflammatory factors ... effect and is highly specific to GR. Furthermore, B53 is able to significantly relieve dermatitis on a ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2022 - American Chemical Society | Journal of Medicinal Chemistry
Neeraj Gupta, Zhiwu Yan, Patricia LoRusso, Justin L. Ricker, Dawn M. Carlson, Rajendra Pradhan,
... Information: Mol Cancer Ther 2009;8(12 Suppl):B53.
Tópico(s): Advanced Breast Cancer Therapies
2009 - American Association for Cancer Research | Molecular Cancer Therapeutics
Amos B. Oppenheim, Susan Gottesman, Max E. Gottesman,
... of lacZ from pL takes place in the b53 deletion (−252 base-pairs to −160 base-pairs) but not in wild-type phage. The b53 deletion thus removes the tI terminator. It also ...
Tópico(s): Bacterial Genetics and Biotechnology
1982 - Elsevier BV | Journal of Molecular Biology
Lilien Chertkoff, Mariana Herrera Piñero, A. H. Mota, Ethel Palavecino, Leonardo Fainboim, M. Leonardo Satz,
... 4c" antigenic cluster (HLA-B18, B51, B52 and B53) showed that the EcoRV/4.6 kb-band ... in 5/5 B52 cells and 4/4 B53 samples.
Tópico(s): Immunotherapy and Immune Responses
1988 - Elsevier BV | Human Immunology
A model of cathode catalyst layer (CCL) performance by Perry et al. [ J. Electrochem. Soc. , 145 , 5 (1998)] shows that there exists optimal effective diffusion coefficient of oxygen , which provides close to minimal voltage loss in the CCL. The dependence has two slopes: at , decreases rapidly, whereas for , lowering of due to better oxygen transport is marginal. The value of is proportional to the product of cell current and CCL thickness. Oxygen diffusivity depends on CCL porosity; thus, may serve as a reference ...
Tópico(s): Membrane-based Ion Separation Techniques
2009 - Electrochemical Society | Electrochemical and Solid-State Letters
7R4. Simulating, Analyzing, and Animating Dynamical Systems: A Guide to XPPAUT for Researchers and Students. - B Ermentrout (Dept of Math, Univ of Pittsburgh). SIAM, Philadelphia. 2002. 290 pp. Softcover. ISBN 0-89871-506-7. $63.00.Reviewed by A Mahajan (Dept of Mech Eng and Energy Processes, S Illinois Univ, Carbondale IL 62901).The book is a hands-on tutorial for a software package called XPPAUT. This software package is used for simulating, analyzing, and animating dynamic systems. Essentially, the ...
Tópico(s): Numerical methods for differential equations
2003 - American Society of Mechanical Engineers | Applied Mechanics Reviews
M.G. Guttridge, Christian A. Burr, P. T. Klouda,
... 1 p. 43-46 Identification of HLA-B35, B53, B18, B5, B78, and B17 alleles by the ...
Tópico(s): Blood groups and transfusion
1994 - Wiley | Tissue Antigens
Nickolai V. Kukhtarev, T. Kukhtareva, Sonia Gallegos,
Application of single-beam reflective laser optical interferometry for oil films and droplets in water detection and characterization is discussed. Oil films can be detected by the appearance of characteristic interference patterns. Analytical expressions describing intensity distribution in these interference patterns allow determination of oil film thickness, size of oil droplets, and distance to the oil film from the observation plane. Results from these analyses indicate that oil spill aging ...
Tópico(s): Petroleum Processing and Analysis
2011 - Optica Publishing Group | Applied Optics