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By David Spanier Diplomatic Correspondent, By Our Diplomatic Correspondent, From Our Own Correspondent, By George Clark Pilitical Correspondent, By Paul Routledge, By Our Political Correspondent, By George Clark Political Correspondent, By Our Political Staff, By a Staff Reporter, From Hugh Noyes, From Christopher Walker, By Our Theatre Reporter, From Peter Nichols, From John Chartres, From Ian Murray, From Our Correspondent, From Robert Schuil, From David Watts, By Louis Heren, By Huon Mallalieu, From David Bonavia, By Peter Strafford, From Mario Modiano, From John Woodcock Cricket Correspondent, By Stephen Fox, By Rex Bellamy Squash Rackets Correspondent, By Norman Fox Football Correspondent, By Peter West Rugby Correspondent, By Michael Phillips Racing Correspondent, Geoff Temple, From Ray Kennedy, By Sydney Friskin, by Rodney Cowton, by Roy Close, by Nancy Foy, by Ross Davies, by Keith Lockyer, R.D., Michael Ratcliffe, Stanley Sadie, William Mann, Joan Chissell, Barry Millington, David Williams, Lord Chalfont, Charles Hargrove, Eric Heffer, David Wood, ANTHONY P. HOPKINS, , J. H. H. MACRAE, , CHRISTOPHER THORNE, , S. A. GOURLAY, , HEW WATT, , MICHAEL JEANS, , JOHN BARTLETT, , J. MICHAEL HOARE, , PETER TRENCH, , ABRAHAM MARCUS, , ROBIN WORDSWORTH, , MADEAU STEWART, , By Robert Nowell, Hugh Clayton, C.F.B., By David Blake, By Maurice Corina Industrial Editor, By Edward Townsend, By Melvyn Westlake, By Ronald Pullen Banking Correspondent, By Our Financial Staff, By Christopher Thomas Labour Reporter, By Malcolm Brown, From Peter Norman, By Peter Hill, Frank Vogl, Rodney Cowton, N. J. M. ABBOTT, , N. C. JOHNSON, , P. G. CAUDLE, , M. E. DERBYSHIRE, , Ronald Faux, BY THE FINANCIAL EDITOR, David Blake, Michael Baily, Desmond Quigley, David Robinson, Ray Maughan, Bryan Appleyard, Wallace Jackson Commodities Editor, Ray Maugham, Gerald Ely,

... City, Ocean, The Institute Of Marine Engineers, Msc, Bim, Dickins & Jones, Armc, Henry Butcher & Co, Professional Enterprises. ... premiums), German metal union holds poll on strike, BIM issues election manifesto, Briefly Boost for Queens Moat ...

1978 - Gale Group | TDA

Artigo Revisado por pares

Kazuhiro Ishii, Yoshifumi Adachi, Masakazu Hatanaka, Hiromi Sakamoto, Jun-ichi Furuyama,

Abstract Cell hybrids (BIM) were produced between human neuroblastoma cells (IMR‐32) and thymidine auxotrophs (B3T) of rat nerve‐like cells (B103) in ... to obtain cell lines undergoing stable neuronal differentiation. BIM cells exhibited the growth properties of partial transformation: 1) When the cell growth reached a plateau, BIM cells ceased to proliferate and expressed a differentiated ... they extended neurites. 2) When cultured in methylcellulose, BIM cells formed colonies, indicating that BIM cells have ...

Tópico(s): Nerve injury and regeneration

1990 - Wiley | Journal of Cellular Physiology

Jornais Acesso aberto

Julia Llewellyn Smith, Anthony Harris, Widget Finn, Tunku Varadarajan, Jon Ashworth, A. Markides, Willy Newlands, Anatol Lieven, Brenda Reid (Chariman), M. Dunton, R. W. Morris, Keith Kyle, Ian Brodie and James Bone, Alison Roberts Arts Reporter, Sarah Bagnall, Insurance Correspondent, Andrew Longmore, Harvey Elliott, Ben Preston, Cristina Odone, Philip Howard, Jeremy Kingston, James Bone, Rory Brogan, Rex Hunt, Lynne Truss, Simon Coates, John Jackson, Simon Wilde, Kevin Eason, Colin Narbrough, Geoff Brown, Stuart Jones Tennis Correspondent, Philip Bassett Industrial Editor, Joe Joseph, Arthur Leathley Political Correspondent, Martin Fletcher, Abby Tan, Norman Hammond, Archaeology Correspondent, Martin Flanagan, Alice Thomson Political Reporter, John O'leary, Education Editor, Peter Rayner, Raymond Keene Chess Correspondent, Helmut Schmidt, Richard Evans, Racing Correspondent, Peter Ackroyd, Peter Waymark, Richard Ford Home Correspondent, Alan Hamilton, Robin Young, Pat Blair, Tim Judah, Balkans Correspondent, Rodney Milnes, Sean MacCarthaigh, Stella Tillyard, Daniel Johnson, Robert Bruce, Michael Hamlyn, Janet Bush, Kevin Eason Motoring Correspondent, David Hands, Sarah Bagnall, John Percival, Philip Bassett, Industrial Editor, M. F. Lowe, R. P. Ralph, Kate Muir, Alan Saunders, Susan Gilchrist, Janet Morgan, John Woodcock, George Brock, Michael Theodoulou, Janet Daley, Mohammad Safaei, David Miller, Professor James Drife, Peter Carr, Mabyn Gordon, John Hopkins Golf Correspondent, Alison Roberts, Peter Hill, J. R. Gregory, David Powell Athletics Correspondent, Tim Jones, Transport Correspondent, Raymond Keene, Arthur Leathley and Philip Webster, David Robinson, David Keane, Emma Wilkins, Sue Kernaghan, Andrew Roberts, Paul Marett, Colin Narbrough World Trade Correspondent, Mr Denys Coomber, Arthur Seldon, Roger Boyes, Richard Siddle, Nicholas Bennett, Philip Webster, Political Editor, Kate Alderson, D. P. Marchessini, Julian Muscat, Adam Fresco, Colin Campbell, Mining Correspondent, Richard Duce, Dr James Le Fanu, William Rees-Mogg, Henry Gold, M. K. Ewans, Sara McConnell, Christopher Walker, Kenneth Gosling, Felix Karthaus, P. J. Bucklitsch, Mel Webb, Gerald Larner, Amanda Craig, Bryan Marson-Smith, Peter Riddell, Ben MacIntyre, Alan Lee Cricket Correspondent, Jeremy Bath, Philip Pangalos, Michael Binyon, Diplomatic Editor, Kate Bassett, Michael Horsnell, Nigel Hawkes Science Editor, Benedict Nightingale, Gwen Robinson, Marianne Curphey, Arthur Leathley, Michael Henderson, Tim Wilding, Michael Evans, John Phillips, Kathryn Bingham, Colin Campbell, David Hands, Rugby Correspondent, Richard Ford, Catherine Milton, Christopher Irvine, John Watson,

... of tax spectrum The Bank of Bermuda Limited BIM Ltd Widespread falls Polo The Document Company The ... Kavelle CVa Recruitment Holdings Mercedes-Benz Finance Ltd BIM Ltd Paul a Hendry & Company CJA PA Sharelink ...

1994 - Gale Group | TDA

Artigo Revisado por pares

G. Sassolas, Y. Khalfallah, J.A. Chayvialle, Richard A. Cohen, S. Merabet, Jean-Paul Casez, Pierre Calvet, P. CABRERA,

BIM 23014 (BIM) is a long-acting octapeptide somatostatin analog. We studied the effects of this analog on the secretion of ... in normal men. In the first protocol three BIM doses (125, 250, and 500 μg) and vehicle ... night. In the second protocol, eight men received BIM, administered by constant sc infusion during the night ... infusion. Nocturnal GH secretion was suppressed by the BIM infusion (P < 0.001). GH secretion, stimulated by ... infusion (P < 0.001), was reduced by concomitant BIM infusion (P < 0.001) and was pulsatile during ...

Tópico(s): Growth Hormone and Insulin-like Growth Factors

1989 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism

Jornais Acesso aberto

By George Clark Political Staff, By Alan Hamilton Labour Staff, From Trevor Fishlock Merthyr Tydfil, , From Arthur Reed Air Correspondent, From Michael Hornsby, From Christopher Walker, From Our Correspondent, By Stephen Jessel Educational Correspondent, From Our Education Correspondent, By Peter Waymark, From Robert Fisk, By Paul Routledge Labour Correspondent, By Our Medical Correspondent, By Frank Roberts Local Government Correspondent, By Our Agricultural Correspondent, By Our Political Staff, By John Roper Medical Reporter, Sally White, By Our Architectural Reporter, By Our Transport Correspondent, By David Wood Political Editor, By a Staff Reporter, From Harry Golombek Chess Correspondent, From Dan van der Vat, From Roger Berthoud, From Ian Murray, Labour Staff, By Our Communications Reporter, From Our Own Correspondent, From Charles Hargrove, From Richard Wigg, From Our Latin America Correspondent, From Fred Emery, From Eric Marsden, From David Housego, By Rex Bellamy Tennis Correspondent, By Michael Phillips Racing Correspondent, By Pamela Macgregor-Morris, By Julian Mounter Motoring Correspondent, Katie Stewart, Tom Milne, John Percival, Joan Chissell, Irving Wardle, William Mann, Charles Lewsen, Stanley Sadie, Richard Harris, Patrick Brogan, Ian McDonald, PHS, Hugh Munro, GORDON BOWEN, , ARTHUR LING, , C. PIENING, , F. WAYNE KING, , MARK K. BENENSON, , C. C. ADDISON, , R. B. PINK, , TRUDIE DEMBOVITZ, , KENNET, , TONY DE ALWIS, , WILLIAM PICKLES, , WYN ROBERTS, , TONY SMYTHE, , DON GRESSWELL, , DAVID WINNICK, , DESMOND LEE, , IRIS C. LESLIE, , PAUL TYLER, , FRANK SPENCER, , By Our Coins Correspondent, From Our Berlin Correspondent, By Andrew Wilson, By Sally White, From Frank Vogl, By Our Financial Staff, By Anthony Rowley, By Philip Dyer, By Maurice Corina Industrial Editor, By R. W. Shakespeare Northern Industrial Correspondent, By Clifford Webb Midland Industrial Correspondent, By Richard Spiegelberg, By Guy Hawtin, By Malcolm Brown, By Dennis Dwyer, By Peter Hill, By Our Air Correspondent, By Ronald Kershaw Northern Industrial Correspondent, From John Earle, Adrian Hope, BY THE FINANCIAL EDITOR, P. ALLEN, , A. LAWSON, , RUTH COLYER, , E. G. WHITE, , By Roger Vielyove, M. B. DANIELS, , From Our US Economics Correspondent, DONALD BARKSHIRE, , R. M. JENKINS, , M. T. W. JEANS, , Guy Hawtin, Kenneth Owen, Philip Dyer, Gerald Ely,

... 25 pc, A chill wind blows along the BIM's corridors, Japan car firm signs pact to ... answer charges, Business Diary: 'Forthright' manager for the BIM Joker from Eastern Airlines, Fresh strike halts second ...

1972 - Gale Group | TDA

Carta Acesso aberto Revisado por pares

Sophie C. Cazanave, Gregory J. Gores,

... proteins, include BH3-interacting domain death agonist (Bid), Bim, Bmf, p53 up-regulated modulator of apoptosis (Puma), ... messengers induce cell death remain controversial; however, Bid, Bim, and Puma are thought to directly activate the ... death domain agonist; Bik, Bcl-2 interacting killer; Bim, Bcl-2 interacting mediator of death; Bmf, Bcl- ... 7 and ultimately apoptosis. The BH3-only protein Bim is also crucial to Fas-mediated apoptosis. Bim, which can be phosphorylated and activated by JNK, ... xL neutralize the deleterious effects of Bid and Bim, and may also directly prevent Bax and/or ...

Tópico(s): Liver physiology and pathology

2009 - Lippincott Williams & Wilkins | Hepatology

Jornais Acesso aberto

By Maurice Corina Industrial Editor, By Our Political Editor, From Robert Fisk, By Paul Routledge Labour Correspondent, By Our Business News Staff, By Arthur Reed Air Correspondent, From Dan van der Vat, By a Staff Reporter, By Hugh Noyes Parliamentary Correspondent, From Our Correspondent, By Ian Murray Labour Staff, From Arthur Osman, By Our Social Services Correspondent, By Our Medical Correspondent, By Our Legal Correspondent, By Our Labour Staff, By Philip Howard, Christopher Walker, Sally White, By John Roper, Medical Reporter, From Our Correspondent Bristol, June 8, From Roger Berthoud, From Pearce Wright and Roger Choate, From Roger Choate, From David Cross, From Charles Hargrove, From Peter Hazelhurst, From Michael Knipe, From Our Own Correspondent, From Ian McDonald, From Fred Emery, By Our Religious Affairs Correspondent, By Louis Heren, From Philip Short, From Michael Hornsby, From Mario Modiano, From Michael Wolfers Africa Correspondent, John Russell Taylor, Irving Wardle, Stanley Sadie, R.M., S.W., Joan Chissell, Charles Lewsen, William Mann, Kate Stewart, By John Woodcock Cricket Correspondent, By Rex Bellamy Tennis Correspondent, By John Nicholls, By Neil Allen Athletics Correspondent, By Jim Railton, By Michael Phillips Racing Correspondent, Golf Correspondent By Peter Ryde, By Pamela Macgregor-Morris, Michael Baily Transport Correspondent, Neil Allen, PHS, Stephen Jessel Education Correspondent, S. P. Q. RAHTZ, , PETER KEMP., DAVID W. PENNICK., FALKNER WINTON, JOHN WATSON, , DAHLIA SAXBY., ANN HARDING., DAVID CROUCH., TONY CROWE, , S. COWAN., F. CLANCY., MONEM A. K. el-ALFI, , MONTAGUE COHEN., YASMA CANAAN., PETER CREW., H. A. WATERSON, , MICHAEL WOODRUFF., H. CAMPBELL., PETER FORSTER., JOHN WHITLOCK, , By Geraldine Norman Sale Room Correspondent, J.C. writes:, Ed Berman writes:-, From Our Diplomatic Correspondent, H. M. writes:, By Ian Morison, By John Winder, By Peter Hill, From Anthony Thomas, By Andrew Wilson, By A. Goodrick-Clarke, By Melvyn Westlake, By Our Economics Staff, By Guy Hawtin, BY THE FINANCIAL EDITOR, HANS WOLFF., HAROLD C. EAGERS, J. WRIGHT., CLAUDE JOHNSON., R. L. JONES, , MARGARET LILEY., R. GARRATT, , A. D. CARSTAIRS., ROBERT W. MOWAT, , Kenneth Owen, Robert Jones, By Gerald Ely, By Patricia Tisdall, By Business News Staff, Philip Dyer, John Whitmore, by Valerie Gilbert, by Michael Toynbee editor, Conferences, Exhibitions & Executive Travel, by Helen McGregor, by Richard Brooks, by Peter Hobday, by Anthony Charles, by William Webb, by Michael Duke, by John Lawless, Philip Howard reports,

... Bulgarian plot. Business and Finance: The Money Supply, BIM working party takes hard look at redundancy, Equities ... 2 more supertankers, Muddled priorities on redundancy from BIM, Arrest warrant for bank chief, 100 workers at ...

1972 - Gale Group | TDA

Artigo Revisado por pares

Edurne San José‐Eneriz, Xabier Agirre, Antonio Jiménez‐Velasco, Lucía Cordeu, Vanesa Martı́n, Víctor Arqueros, Leire Gárate, Vicente Fresquet, Francisco Cervantes, José A. Martínez-Climent, Anabel Heiniger, António Torres, Felipe Prósper, José Román‐Gómez,

... of the pro-apoptotic BCL-2-interacting mediator (BIM) has recently been implicated in imatinib-induced apoptosis ... However, the mechanisms involved in the regulation of BIM in CML and its role in the clinical ... and methods We analysed the mRNA expression of BIM in 100 newly diagnosed patients with CML in ... and were transfected with two different siRNAs against BIM and cell proliferation and apoptosis were analysed. Results We demonstrated that down-regulation of BIM expression was present in 36% of the patients ...

Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment

2009 - Elsevier BV | European Journal of Cancer

Livro

Springer Link

Jornais Acesso aberto

From Brian Cashinella, By Our Political Editor, From Our Correspondent, By a Statt Reporter, By Giles Smith, From Christopher Walker, By Our Parliamentary Correspondent, By Sally White, By Paul Routledge, By Our Labour Staff, By Our Political Staff, By Our Agricultural Correspondent, From Jeremiah O'Leary, From Richard Wigg, From Our Own Correspondent, From Derek Wilson, By Peter Reddaway, By Geraldine Norman Sale Room Correspondent, From David Housego, From Roger Choate, By Jim Snow Northern Racing Correspondent, By Julian Mounter Motoring Correspondent, By Rex Bellamy Tennis Correspondent, By Peter Ryde Golf Correspondent, From Sydney Friskin, By Peter West Rugby Correspondent, By Geoffrey Green Football Correspondent, Andrew Graham, Harry Golombek, David Wade, Stephen Walsh, Joan Chissell, Ronald Hayman, Guy Brett, William Mann, Sir Hugh Greene, Roy Hay, Katie Stewart, Edward Mayer, John Carter, Ronald Faux, Chris Dunkley, Leonard Amey, PHS, Tony Aldous, ELIZABETH HURSTFIELD., BROCKWAY, , C. DAY-LEWIS, ISAIAH BERLIN, PETER CALVOCORESSI, HUGH GREENE, IRIS MURDOCH, WILLIAM PLOMER, MAX REINHARDT STEPHEN SPENDER., ROSALIE WOODMAN, , ROBIN DARWIN., W. E. S. BOND., FRED PEART, , WILLIAM SHEPHERD., WILLIAM ROSE, , CLAUDE SIMMONDS., J. K. COLVILLE, , ANDREW FAULDS., BERAM SAKLATVALA., ARRAN, , REX ROBERTS., RONALD L. JOHNSON, , ANTONY BUCK, PHILIP GOODHART., PHILIPPA PULLAR., KAY DICK, , JOAN DAMPNEY, , BEAUMONT OF WHITLEY, , By Dr Alistair Kee, , J.M.R., G.O.N., prof D. S. Lees, Sir John Partridge, By Anthony Rowley, By R. W. Shakespeare Northern industrial Correspondent, By Business News Staff, By Arthur Reed Air Correspondent, From Fred Emery, By Dennis Dwyer, By Kenneth Owen, From David Cross, By Melvyn Westlake, By A. Goodrick-Clarke, BY THE FINANCIAL EDITOR, By Roger Vielvoye, By Paul Routledge Labour Staff, Halldora Blair, MARGARET STONE, Margaret Stone, John Drummond, By Richard Spiegelberg, J.D., By Innis Macbeath, Ronald Irving,

... explained, Stainless steel stockists may benefit from discount, BIM criticizes industry code as ineffective, Company Meeting SIME ...

1971 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Sophie C. Cazanave, Justin L. Mott, Nafisa A. Elmi, Steven F. Bronk, Nathan W. Werneburg, Yuko Akazawa, Alişan Kahraman, Sean Garrison, Gerard P. Zambetti, Michael Charlton, Gregory J. Gores,

... pro-apoptotic members of the Bcl-2 family Bim, Bad, and Bax (26Lei K. Davis R.J. ... This group of proteins includes Bad, Bid, Bik, Bim, Bmf, Hrk, NOXA, and PUMA, which display sequence ... induce apoptosis. BH3-only proteins such as Bid, Bim, and PUMA can directly activate the multidomain pro- ... 1871) Google Scholar). Among the BH3-only proteins, Bim has been identified as contributing to lipoapoptosis (12Barreyro ... 163) Google Scholar). Indeed, saturated FFA up-regulates Bim expression, and small interfering RNA targeted knockdown of ...

Tópico(s): Lipid metabolism and biosynthesis

2009 - Elsevier BV | Journal of Biological Chemistry

Livro

Springer Link

Jornais Acesso aberto

By John Whitmore Financial Staff, By Anthony Rowley Financial Staff, From Nicholas Ashford, From George Clark and Martin Huckerby, By Tim Jones Labour Staff, By Our Labour Staff, By a Staff Reporter, From Robert Parker, By Our Political Staff, From Christopher Walker, By David Leigh, By Clive Borrell, From Our Correspondent, By Michael Hatfield Political Staff, From Our Veterinary Correspondent, By Our Medical Reporter, From Fred Emery, By Ronald Kershaw Northern Industrial Correspondent, By Staff Reporters, By John Young Planning Reporter, By Our Education Correspondent, From Charles Hargrove, From Our Own Correspondent, From Dan van der Vat, West German elections, From Roger Berthoud, From Richard Wigg, From Our Parliamentary Staff, From Michael Knine, From Frank Vogl, From Robert Fisk, From Eric Marsden, Geraldine Norman, European Parliament Luxembourg, By Michael Seely, By Michael Phillips Racing Correspondent, By a Special Correspondent, By Gerry Harrison, From Norman Fox Football Correspondent, By John Blunsden, By Neil Allen Boxing Correspondent, Paddy Kitchen, Ned Chaillet, Irving Wardle, Stanley Reynolds, William Mann, Keith Horner, Gerald Ely, Bernard Levin, Colin Lovelace, PHS, MARGARET MALLETT., BERTRAM L. BARNBY., WINSTON S. CHURCHILL, J. C. SLESSOR, MRAF., FRANCIS PERKINS., RONALD COHEN, , DAVID HOLBROOK., RONALD M. BELL, , DAVID ROFFEN:, A. M. KHAN., S. A. MALIK., M. THAIN, , THOMAS BRAUN, , PAULINE STEVENS., By Our Horticultural Correspondent, From Christopher Warman Local Government Correspondent, By Our Planning Reporter, by Eric Fordham, E. F., by Alan Grainge, Melvyn Westlake Economics Staff, By Clifford Webb, By Margaret Stone, From Patrick Brogan, By Business News Staff, By Peter Hill, From Michael Hornsby, John Brennan, BY THE FINANCIAL EDITOR, KENNETH ADAMS., M. H. N. POTOK., P. A. HILL, , J. HAZLETON, , From Frank Vogl US Economics Correspondent, By Kenneth Owen, By Ronald Emler, B. DURANT, By Maurice Corina Industrial Editor, By Desmond Quigley,

... British Mohair spinning its way to new peak, BIM wants more say by management, Wood & Sons (Holdings) ...

1976 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Martina Klee, Kathrin Pallauf, Sonia Alcalá, Aarne Fleischer, Felipe X. Pimentel‐Muiños,

... to trigger mitochondrial apoptosis (Mund et al, 2003). Bim mediates death induced by ER stress (Puthalakath et al, 2007), a process that involves Bim translocation to reticular membranes (Morishima et al, 2004). ... Bax. We found that the BH3-only molecules Bim and Puma are able to fully induce cytochrome ... C) Polyclonal AU-Bak–cb5-expressing cells undergo Bim- and Puma-induced apoptosis. Cells were transduced with ... h later. The inset shows expression of HA-Bim, HA-tBid and HA-Puma in bak,bax−/− ... pathways by overexpressing the BH3-only molecules BimEL (Bim hereafter), tBid and Puma, three family members known ...

Tópico(s): Endoplasmic Reticulum Stress and Disease

2009 - Springer Nature | The EMBO Journal

Jornais Acesso aberto

Douglas Houghton, Victoria McKee, Bob Ross, Anatol Lieven, Peter Evans, Mark Souster and Michael Horsnell, J. A. Davis Clerk to the Justices, David Rhys Jones, Cliff Feltham, Sally Brompton, Robin Oakley, Hilary Finch, F. A. Mann, Jeremy Kingston, Clifford Longley Religious Affairs Editor, James Bone, Clive Davis, Wilson, Richard Evans, Media Editor, Carol Leonard, Stuart Jones Football Correspondent, Pat Butcher Athletic Correspondent, Heather Neill, Colin Narbrough, Margareta Pagano, Michael Seely Racing Correspondent, Joe Joseph, Martin Fletcher, Mitchell Platts, Golf Correspondent, Peter Ball, Jill Sherman, Social Services Correspondent, Clare Hogg, Donatella Lorch, Louise Taylor, Roland Rudd Employment Affairs Reporter, Thomson Prentice Science Correspondent, David Tytler Education Editor, Peter Waymark, Peter Bills, Sir Charles Morrison, David Smith Economics Correspondent, Shona Crawford Poole, Travel Editor, George Thomson, David Hands, Edward Gorman, Thomson Prentice, Norman de Mesquita, David Rowan, David Young and Pearce Wright, B. H. Parker (Councillor, British Orienteering Federation), Steven Downes, Gavin Bell, David Cross, Peter Warner, Nicholas Harling, Dennis Signy, Chris Thau, (Michael Phillips), Alan Toogood, Horticulture Correspondent, Wolfgang Münchau, Meredith Etherington-Smith, Jill Sherman and Nicholas Wood, David Lindley, Catherine Sampson, M. J. Boleat Director-General, Philip F. Nind, Peter Davalle, Müller, Craig Brown, Steve Acteson, Peter Bryan, Stewart Tendler Crime Reporter, Richard Evans, Craig Seton, Richard Owen, Paul Charman, Martin Searby, Irving Wardle, Ian Ross, Geoffrey Foster, David Sapsted, David Crouch, Derek Harris, Industrial Editor, Brian Beel, Keith MacKlin, David Hands Rugby Correspondent, Jamie Dettmer, David Brewerton, Susan Jowett, Jill Sherman Social Services Correspondent, Philip Kleinman, Iain MacLeod, D. Grant Lawrence, Graham Searjeant, Financial Editor, Clive White, Matthew Parris, Sarah Jane Checkland Art Market Correspondent, Jonathan Rendall, Michael Seely, Owen Jenkins, Alan Lee Cricket Correspondent, Denis Mahon, Philip Webster, Andrew Lycett, Stephen Pettitt, Roper Mead (former Assistant Secretary, Press Council), Frances Rice, (Chairman), Martin Waller, George Chesterton, Noël Goodwin, Tim Jones and Roland Rudd, David Nicholson-Lord, Cliff J. Patterson, Alan Amos, R. J. Worden, Amir Taheri, Colin Campbell, Tony Hetherington, David Young Energy Correspondent, Philip Jacobson, Ann Hills, Ray Whitney, Brian Davis, Vivien Goldsmith, Family Money Editor,

... in £7.6m deal New Tokyo stake for BIM SA stake in North Sea New credit card ...

1989 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Kostas Paschos, Paul Smith, Emma Anderton, Jaap M. Middeldorp, Robert E. White, Martin J. Allday,

... of the pro-apoptotic Bcl-2-family member Bim and enhance cell survival. This involves the activities ... and appears to be predominantly directed at regulating Bim mRNA synthesis, although post-transcriptional regulation of Bim has been reported. Here we show that protein ... no contribution to the EBV-associated repression of Bim in latently infected B cells. However, treatment of ... mechanisms are involved in the down-regulation of Bim. This was initially confirmed by chromatin immunoprecipitation analysis ...

Tópico(s): Histiocytic Disorders and Treatments

2009 - Public Library of Science | PLoS Pathogens

Jornais Acesso aberto

By Davir Spanier, By Marcel Berlins Legal Correspondent, By Henry Stanhope Defence Correspondent, From Charles Hargrove, By Melvyn Westlake, By George Clark Political Correspondent, By Stewart Tendler Crime Reporter, From Patricia Clough, By Paul Routledge Labour Editor, By Arthur Osman, By Stewart Tendler and Robert Parker, By Margaret Stone, From Our Own Correspondent, By David Nicholson-Lord, By Michael Baily Transport Correspondent, By John Roper Health Services Correspondent, By Donald Macintyre Labour Reporter, By Robin Young Consumer Affairs Correspondent, By Our Consumer Affairs Correspondent, By Stewart Tendler, From Our Correspondent, From Ronald Faux, From Ian Bradley, By Annabel Ferriman, From John Groser, By Pearce Wright Science Editor, From Diana Geddes Education Correspondent, By Our Religious Affairs Correspondent, From Michael Hornsby, From Peter Nichols, From Ian Murray, From Michael Binyon, By Our Foreign Staff, From James Reston New York Times columnist, From David Watts, , From Michael Knipe, From Peter Hazelhurst, From David Cross, From Diana Patt, From Richard Wigg, From David Bonavia, John Higgins, Paddy Kitchen, Stanley Reynolds, William Mann, Barry Millington, Irving Wardle, John Pereival, Ned Chaillet, By Tom German, By Srikumar Sen, By a Staff Reporter, By Ronald Faux, From Christopher Plumridge, By Jim Railton, By Rex Bellamy Squash rackets Correspondent, Cliff Temple, By Michael Phillips Racing Correspondent, Ronald Butt, Philip Howard, Dr Mervyn Stockwood, , PHS, John Biffen, TOM SHARPE, , P. W. SHARMAN, , SIDNEY R. CAMPION, , PETER ROBERTS, , JOHN TILNEY, , MAURICE BRUCE, , BROCKWAY, , JULIAN CRITCHLEY, , WILLIAM WRIGHT, , JOAN E. WHEELER-BENNETT, , ZOE HERSOY, , BEATRICE MUSGRAVE, , P. A. KEEN, , ECCLES, , DAVID MILLE DANIEL, , CHARLOTTE HORSFIELD, , E. A. VINCENT, , By Our Diplomatic Correspondent, By Geraldine Norman Sale Room Correspondent, By Our Music Reporter, Two fellow officers, Mr George Mikes, A. H. P. N., Michael Ratcliffe, Myrna Blumberg, Sheridan Morley, Tom Hutchinson, E. C. Hodgkin, by Prudence Glynn, By Patricia Tisdall, By Our Banking Correspondent, By Roger Vielvoye Energy Correspondent, From Michael Leapman, From Frank Vogl, By Maurice Corina Industrial Editor, By Caroline Atkinson, By Malcolm Brown, Christopher Wilkins, By Ronald Kershaw, By Peter Hill Industrial Correspondent, By R. W. Shakespeare, ST JOHN ELSTUB, , JOHN ATWELL, , CHARLES PRINGLE, , R. C. COATES, , G. A. DUMMETT, , C. N. THOMPSON, , P. MORETON, , LESLIE BIRTS, , BY THE FINANCIAL EDITOR, David Blake, By Bryan Appleyard, By Victor Felstead, By Ray Maughan, By Our Financial Staff, By Margaret Drummond, Peter Waymark, Jacqueline Grapin, Pangloss, by David Blake, by Maurice Bommensath, by Leo Fischer, by Heinz Pentzlin, by Peter Gillies, by Michel Godet and Olivier Ruyssen, by Michael Hornsby, by Sergio Devecchi, by Hans Baumann, by Jacques Attali,

... Reports, Leyland loss cancels NEB profit from Rolls, BIM rejects statutory profit Plan, Eurosyndicat, Commodities, Building a ...

1978 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Brona M. Murphy, Tobías Engel, Alexia Paucard, Seiji Hatazaki, Genshin Mouri, Katsuhiro Tanaka, Liam P. Tuffy, Eva M. Jiménez‐Mateos, Ina Woods, Mark Dunleavy, Helena P. Bonner, Robert Meller, Roger P. Simon, Andreas Strasser, Jochen H.M. Prehn, David C. Henshall,

... protein, Bcl-2 interacting mediator of cell death (Bim), increased in the rat hippocampus but not in ... onset status epilepticus. In this study, we examined Bim expression in mice and compared seizure damage between wild-type and Bim-deficient animals. Status epilepticus induced by intra-amygdala ... factors associated with transcriptional and posttranslational activation of Bim, such as CHOP and c-Jun NH(2)- ... kinases, was significant within 1 h. Upregulation of bim mRNA was evident after 2 h and Bim protein increased between 4 and 24 h. Hippocampal ...

Tópico(s): Ubiquitin and proteasome pathways

2009 - Springer Nature | Cell Death and Differentiation

Periodico Acesso aberto

SciELO

Artigo Acesso aberto Revisado por pares

Nicolas Houde, Estelle Chamoux, Martine Bisson, Sophie Roux,

... may activate the intrinsic apoptosis pathway, which involves Bim, the expression of which was increased in the ... TGF-β1-induced osteoclast apoptosis was lower when Bim expression was suppressed, and inhibiting the Smad pathway abolished Bim up-regulation following TGF-β stimulation. This could ... may activate the intrinsic apoptosis pathway, which involves Bim, the expression of which was increased in the ... TGF-β1-induced osteoclast apoptosis was lower when Bim expression was suppressed, and inhibiting the Smad pathway ...

Tópico(s): Bone health and treatments

2009 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

From JOHN CHARTRES and GARRY LLOYD, By a Staff Reporter, From LOUIS HEREN, By Our Foreign Staff, From JOHN ROPER, From Our Churches Correspondent, From David Wilsworth, From RONALD FAUX, BY OUR POLITICAL STAFF, BY A STAFF REPORTER, By PETER EVANS, By STEPHEN JESSEL, From CHARLES HARGROVE, From HAROLD FRANKLIN, By ROY LEWIS, From Our Correspondent, From PAUL HOFMANN, Our Paris Correspondent, FROM OUR OWN CORRESPONDENT, From DAVID BONAVIA, From DAN VAN DER VAT, From Our Own Correspondent, From PAUL MARTIN, FROM OUR CORRESPONDENT, From LEO GOODSTADT, By JOHN WOODCOCK, Cricket Correspondent, By PETER MARSON, By U. A. TITLEY, By ANDREW PORTER, By JOHN NICHOLLS, By Our Rifle Shooting Correspondent, From Our Special Correspondent, From an Irish Racing Correspondent, By Our Racing Correspondent, By Our Newmarket Correspondent, By Our Northern Correspondent, From ST. JOHN DONN-BYRNE, By JIM RAILTON, By REX BELLAMY, Tennis Correspondent, By NEIL ALLEN, Athletics Correspondent, David Wood Political Editor, John Chartres, MICHAEL LEAPMAN, PHS, By George Clark, GERALD HOWARTH, TREVOR HUDDLESTON, BEAUMONT OF WHITLEY, DAVID M. S. STEEL, ANDREW FAULDS, PATRICK WALL, BYRON CRIDDLE., DAVID BARNES., CARL FOREMAN, LARRY ADLER., PETER H. LEARNER, JOHN HUNT, By Squadron Leader Tony Nicholson, ELIZABETH VICE, GRAHAM SANSBURY, E. M. COCKBURN., By LEONARD AMEY, From ANTHONY SMITH, Sir Dingle Foot, By John Percival, By Karl Dallas, Leonard Buckley, Alan Blyth, By Alan Blyth, By Stanley Sadie, by Penny Hunter Symon, By Nature Times News Service, By GERALD ELY, By MICHAEL THOMAS, Labour Correspondent, By CLIVE CALLOW, Our Economic Staff, By GEORGE CLARK, Political Staff, By HUGH STEPHENSON, By CLIFFORD WEBB, Midland Industrial Correspondent, By ROSS DAVIES, From MICHAEL BAILY, Shipping Correspondent, From FRANK VOGL, By GILES SMITH, MALCOLM BROWN, By ANTHONY ROWLEY, European Industrial Correspondent, BY THE FINANCIAL EDITOR, DOROTHY HENRY, J. A. OOCHRANE, RONALD KERSHAW, H. P. CARSE, Anthony Thomas, Anthony Rowley, BERRY RITCHIE, Edited by Robert Jones, Robert Jones, Joe Roeber, Gillian O'Connor, Innis Macbeath, By JOHN WOODLAND,

... BSC dispute, Phillips evaluates N Sea oil strike, BIM sets up new centre, company NEWS Wiggins Teape ...

1970 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Shuang Chen, Yun Dai, Xin‐Yan Pei, Steven Grant,

... kills transformed cells in association with displacement of Bim from Bcl-2. The histone deactetylase (HDAC) inhibitor ... ABT-737 might interact with agents that upregulate Bim. Expression profiling of BH3-only proteins indicated that SBHA increased Bim, Puma, and Noxa expression, while SBHA concentrations that upregulated Bim significantly potentiated ABT-737 lethality. Concordance between SBHA-mediated Bim upregulation and interactions with ABT-737 was observed ... various human leukemia and myeloma cells. SBHA-induced Bim was largely sequestered by Bcl-2 and Bcl- ...

Tópico(s): Multiple Myeloma Research and Treatments

2009 - Taylor & Francis | Molecular and Cellular Biology

Jornais Acesso aberto

By DAVID WOOD, Political Correspondent, From ROGER NICHOLSON, From HENRY KAMM, BY A STAFF REPORTER, By PETER RYDE, From Our United Nations Correspondent, By the News Team, FROM OUR NORTHERN CORRESPONDENT-Hull, Oct. 15, BY CLIVE BORRELL, By Our Education Correspondent, By GEOFFREY CHARLES, Motoring Correspondent, BY OUR POLITICAL STAFF, By a Staff Reporter, FROM A STAFF REPORTER-Cambridge, Oct. 15, By PHILIP HOWARD, By RITA MARSHALL, From PETER STRAFFORD-Brussels, Oct. 15, From Our Correspondent, FROM OUR OWN CORRESPONDENT-Washington, Oct. 15, FROM OUR OWN CORRESPONDENT-Paris, Oct. 15, From MICHAEL WOLFERS-Lagos, Oct. 15, From Our Own Correspondent, From Our Special Correspondent, From FRED EMERY-Singapore, Oct. 15, From HILARY BRIGSTOCKE-Ottawa, Oct. 15, FROM OUR OWN CORRESPONDENT-Tokyo, Oct. 15, By Nature-Times News Service, June Rose, Prudence Fay, From HUGH NOYES, Parliamentary Correspondent-Westminster, Tuesday, From Mr. J. W. Pardoe, Liberal M.P. for Cornwall, North, J. W. PARDOE., From Mr. Graham H. Greenwell, GRAHAM H. GREENWELL., From Mr. K. M. Feeny, K. M. FEENY., From Sir Herbert Thompson, HERBERT THOMPSON., From Professor S. C. Harland, F.R.S., S. C. HARLAND., From Dr. Enid Starkie, ENID STARKIE., From Mr. P. A. Davidson Smith, P. A. DAVIDSON SMITH, From Mr. Nicolas Bentley, NICOLAS BENTLEY., From Major-General Sir Miles Graham, MILES GRAHAM, From Mr. Richard L. Bishop, RICHARD L. BISHOP., From Mr. Leonard Woolf, LEONARD WOOLF., From Miss Katherine Hudson, KATHERINE HUDSON., From Mr. S. O. Speakman, S. O. SPEAKMAN., From Mr. John Wyndham, JOHN WYNDHAM., From Mr. Simon Griffin, SIMON GRIFFIN., By Sir Oswald Mosley, From Mrs. N. E. Mustoe, ANNE MUSTOE., From Mr. R. W. Ellis, R. W. ELLIS, From Mr. Fred Uhlman, FRED UHLMAN., From Mr. Roger Stratford, ROGER STRATFORD, From NEIL ALLEN, From DAVID CAZES, From REX BELLAMY, From GINA HUNT, From RONALD FAUX, By MICHAEL PHILLIPS, Racing Correspondent, By GEOFFREY GREEN, Football Correspondent, By PETER MARSON, By BRIAN MOORE, By BEVIS HILLIER. Sale Room Correspondent, By ANTHONY THOMAS, Banking Correspondent, By HUGH STEPHENSON, From MAURICE CORINA-Oslo, Oct. 15, By CHRISTOPHER MARLEY, By MICHAEL THOMAS, Labour Staff, BERRY RITCHIE, By JAMES DAGLISH, By CLIFFORD WEBB Midland Industrial Correspondent, DAVID DAVIS, BY THE FINANCIAL EDITOR, From PAUL HORNE, BY BUSINESS NEWS STAFF, EWART PARKINSON., JOHN GRAHAM, FROM THE LONDON GAZETTE, by Douglas Armstrong, by Bernard Cahier, by Martin Lewis, by Eric Dymock, by Stuart Marshall, by Patrick Macnaghten, by Jerry Ames, by Alan Baker, Group Managing Editor, Automotive Design Engineering, by Harold Dvoretsky, Australian Consolidated Press, by Alan Brinton, by Edward Eves, by Bob Campbell, by Christopher Meakin, by Dennis May, by Harry Heywood, by Phil Drackett,

... peak, Why we dropped English bid-by Plessey, BIM accent on marketing, BUSINESS diary A crucial year ...

1968 - Gale Group | TDA