Produção Nacional
Revisado por pares
Rafael Carneiro Bastos, Carlos Franciney Moreira Vasconcelos, Marcela Bezerra Paiva, Thomas Dominik de Sousa dos Reis, Ricardo Basto Souza, Hélcio Silva dos Santos, Paulo Nogueira Bandeira, Lissiana Magna Vasconcelos Aguiar, Rodrigo Maranguape Silva da Cunha,
Oxidative stress is related to health problems including neurological and neurodegenerativedisturbs, such as Parkinson's disease. Natural compounds are reported as source of antioxidant molecules. Therefore, this study aimed to analyze the antioxidant and neuroprotective potential of a new diterpene isolated from C. argyrophylloides (MP-1). Male Wistar rats (250-300 g) were used to evaluate MP-1 antiparkinsonian potential through neurodegenerative model induced by the neurotoxin 6-hydroxydopamine ( ...
Tópico(s): Biological and pharmacological studies of plants
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