Produção Nacional
Revisado por pares
Dérica Gonçalves Tavares, Bárbara Viana Lessa Barbosa, Rodrigo Lopes Ferreira, Whasley Ferreira Duarte, Patrícia Gomes Cardoso,
Few studies have been carried out on the biotechnological potential of microorganisms growing inside caves. Fungi are found in several environments and are sources of metabolites that present biological activities and can be used for industrial purpose. The objective of this study was to evaluate the antioxidant activity and phenolic compounds of extract from pigment-producing fungi isolated from Brazilian caves. The antioxidant activity was evaluated using the free radical scavenging methods 1, ...
Tópico(s): Phytochemicals and Antioxidant Activities
2018 - Elsevier BV | Biocatalysis and Agricultural Biotechnology
Produção Nacional
Revisado por pares
Rafael de Almeida Barros, Yaremis Meriño‐Cabrera, Camilo Elber Vital, Neilier Junior, Cauê N de Oliveira, Samuel Lessa Barbosa, João V Marques Gonçalves Assis, Humberto JO Ramos, Maria Goreti de Almeida Oliveira,
Abstract BACKGROUND Anticarsia gemmatalis larvae are key defoliating pests of soybean plants. Inorganic insecticides, harmful to the environment and human health, are the main molecules used in the control of this pest. To apply more sustainable management methods, organic molecules with high specificities, such as proteinaceous protease inhibitors, have been sought. Thus, molecular docking studies, kinetics assays, and biological tests were performed to evaluate the inhibitory activity of two peptides ( ...
Tópico(s): Insect Pest Control Strategies
2020 - Wiley | Pest Management Science
Produção Nacional
Revisado por pares
Yaremis Meriño‐Cabrera, Tiago Antônio de Oliveira Mendes, José Gregório Severiche Castro, Samuel Lessa Barbosa, Maria Lı́gia Rodrigues Macedo, Maria Goreti de Almeida Oliveira,
The economic loss in soybean crops caused by the Lepidoptera insects has encouraged the search for new strategies to control this pest, which are currently based on synthetic insecticides. This paper evaluated the ability of ApTI (Adenanthera pavonina trypsin inhibitor) to inhibit trypsin-like proteins from Anticarsia gemmatalis by docking, molecular dynamics, and enzymatic and survival assay. The docking and molecular dynamic simulation between trypsin and ApTI were performed using the program CLUSPRO ...
Tópico(s): Computational Drug Discovery Methods
2020 - Wiley | Archives of Insect Biochemistry and Physiology
Produção Nacional
Revisado por pares
Larissa da Rocha Lessa, Flávio Barbosa Luz, Rebeca Maffra de Rezende, Sandra Maria Barbosa Durães, Ben J. Harrison, Gabriela B. de Menezes, Leonardo F. Fontenelle,
We compared the sociodemographic and psychiatric features of treatment-seeking patients with (n=17) and without (n=29) primary hyperhidrosis (HYH) attending an outpatient dermatological clinic. Subjects were assessed with a structured clinical questionnaire, the Mini International Neuropsychiatric Interview, as well as the Screening for Abnormal Olfactory Experiences (to assess for symptoms of olfactory reference syndrome), the Obsessive-Compulsive Inventory-Revised, the Social Phobia Inventory, the ...
Tópico(s): Migraine and Headache Studies
2014 - Lippincott Williams & Wilkins | Journal of Psychiatric Practice
... 1111/ahe.12247Ana Flávia Ribeiro Machado Michel, Fabiana Lessa Silva, Fernando Sérgio Barbosa, Tatiane Furtado de Carvalho, Jaqueline Maria Silva Pinto, ...
Tópico(s): Evolution and Paleontology Studies
1941 - University of Chicago Press | The Quarterly Review of Biology
Augusto César Ferreira de Moraes, Maria Beatriz Lacerda, Luís A. Moreno, Bernardo Lessa Horta, Heráclito Barbosa Carvalho,
Several studies have reported high prevalence of risk factors for cardiovascular disease in adolescents. To perform: i) systematically review the literature on the prevalence of high blood pressure (HBP) in adolescents; ii) analyze the possible methodological factors associated with HBP; and iii) compare the prevalence between developed and developing countries. We revised 10 electronic databases up to August 11, 2013. Only original articles using international diagnosis of HBP were considered. The ...
Tópico(s): Cardiovascular Health and Disease Prevention
2014 - Wolters Kluwer | Medicine
Produção Nacional
Francisco Barroso da Silva, Geocleber Gomes de Sousa, José Thomas Machado de Sousa, Carla Ingryd Nojosa Lessa, Fred Denílson Barbosa da Silva,
ABSTRACT The objective of this study was to evaluate the production of watermelon seedlings irrigated with saline waters and cultivated in different types of environments and substrates. The experimental design was completely randomized with split-split plots, in which the plot corresponded to two growing environments (EN1 = full sun and EN2 = 50% shade black net), the subplot to two types of irrigation water (IW1 = 0.8 and IW2 = 2.5 dS m-1) and the sub-subplot to four types of substrates (SB1 = vermiculite + ...
Tópico(s): Plant tissue culture and regeneration
2020 - UNIVERSIDADE FEDERAL RURAL DO SEMI-ARIDO | Revista Caatinga
Produção Nacional
Waneska Alexandra Alves, Divanise Suruagy Correia, Lívia Lessa de Brito Barbosa, Leonardo Moreira Lopes, Márcio Ighor Azevedo Silva de Mendo Melânia,
Objetivo: descrever o perfil epidemiológico e a magnitude dos homicídios ocorridos no município de Maceió
Tópico(s): Injury Epidemiology and Prevention
2014 - MINISTÉRIO DA SAÚDE | Epidemiologia e Serviços de Saúde
Produção Nacional
Revisado por pares
Mirelle Nayana de Sousa Santos, Nícolas Oliveira de Araújo, Fernanda Ferreira de Araújo, Mariana Aparecida da Silva, Samuel Lessa Barbosa, Maria Goreti de Almeida Oliveira, Olinto Liparini Pereira, Münevver Doğramacı, Fernando Luíz Finger,
Postharvest losses related to dry rot can reach 60% during long-term storage of potato tubers. Current control methods do not provide an efficient solution to control dry rot, and inducing resistance through elicitors may be a promising way to manage this disease. In this study, we evaluated the ability of 1,4-dimethylnaphthalene (1,4-DMN) and methyl jasmonate (MeJa) to induce resistance to dry rot caused by Fusarium nirenbergiae, using 'Asterix' and 'Challenger' under refrigerated storage conditions. ...
Tópico(s): Plant Disease Management Techniques
2023 - Elsevier BV | Postharvest Biology and Technology
Bruce J. Hillman, Constantine Gatsonis, Daniel C. Sullivan,
... do câncer de pulmão: passado, presente e futuroTHAMINE LESSA E.S.ANDRADE, SORIARAMOS-BARBOSA, JORGE L.PEREIRA-SILVA2002 | Jornal de Pneumologia, Vol. ...
Tópico(s): Radiation Dose and Imaging
1999 - Radiological Society of North America | Radiology
... Gaúchas. J. C. Paixão Cortes and L. C. Barbosa Lessa. (Commissão Nacional de Folclore do I.B.E. ...
Tópico(s): Physical Education and Sports Studies
1958 - Cambridge University Press | Journal of the International Folk Music Council
Produção Nacional
Revisado por pares
Rafaella Ribeiro Sâmia, Natasha Dantas Lorenzo, Bárbara Viana Lessa Barbosa, Ana Luísa Ferreira Fonseca, Cleiton Antônio Nunes, Sabrina Carvalho Bastos,
The heating of oils and fats at high temperatures can lead to an oxidation process that involves a series of complex reactions producing a great diversity of oxidation products, including peroxides and free fatty acids. One of the foods normally prepared by quick frying using oils and fats is chicken eggs. This study aimed to evaluate the percentage of oil and fat absorption, peroxide index, degree of acidity, p-anisidine value, and TOTOX as well as the lipid profile of chicken eggs prepared whole ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2022 - Elsevier BV | International Journal of Gastronomy and Food Science
Produção Nacional
Revisado por pares
Francisco José Gondim Pitanga, Ínes Lessa, Paulo José Bastos Barbosa, Simone Jatene Oliveira Barbosa, Cecília Costa, Adair da Silva Lopes,
OBJETIVO: Analisar a quantidade (intensidade e duração) de atividade física total e em seus diferentes domínios (trabalho, deslocamento, atividade doméstica e tempo livre) como preditores da ausência de diabetes em população de etnia negra. MÉTODOS: Estudo transversal com amostra de 2305 adultos negros de 20 anos a 96 anos de idade, sendo 902 (39,1%) homens, residentes na cidade de Salvador, Bahia, Brasil. Foram construídas curvas Receiver Operating Characteristic (ROC) e comparadas às áreas entre a ...
Tópico(s): Obesity, Physical Activity, Diet
2010 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Produção Nacional
Revisado por pares
Francisco José Gondim Pitanga, Ínes Lessa, Paulo José Bastos Barbosa, Simone Janete Oliveira Barbosa, Cecília Costa, Adair da Silva Lopes,
OBJETIVO: Analisar a prevalência e os fatores sociodemográficos associados aos diferentes domínios da atividade física em adultos de etnia negra. MÉTODOS: Estudo transversal com amostra de 2.305 adultos negros de 20 a 96 anos de idade, sendo 902 (39,1%) homens, residentes na cidade de Salvador, BA, Brasil. Foram analisadas as variáveis sociodemográficas sexo, idade, escolaridade, nível socioeconômico (NSE), estado civil, discriminação racial no trabalho/escola (DRTE), em ambientes públicos (DRAPU) e ...
Tópico(s): Health and Lifestyle Studies
2012 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Aparecida Souza Machado Bruna, Henrique de Oliveira Reis João, Santos Cruz Lindaiá, Ingrid Lessa Leal, Dantas Viana Barbosa Josiane, B.A. Joyce, Izabel Druzian Janice,
The aim of this study was to obtain and characterize biodegradable films of cassava starch plasticized with glycerol and reinforced with nanocellulose from coconut fibers. The mechanical and physical-chemical properties of the nano-biocomposites films obtained were evaluated. The method used to investigate the viability of incorporating coconut nanocellulose in films was applied through a statistical design of the response surface of 17 formulations containing three independent variables (starch, ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2017 - Academic Journals | AFRICAN JOURNAL OF BIOTECHNOLOGY
Produção Nacional
Revisado por pares
Famiely Colman Machado de Machado, Carla Aparecida Cielo, Marcus Miranda Lessa, Luiz Henrique Fonseca Barbosa,
To characterize the voice of elderly people engaged in aerobics.Collection of phonation /a:/ from 58 elderly people engaged in aerobics for perceptual voice analysis (RASATI scale) and computed acoustics (Multi Dimensional Voice Program Advanced, software of Kay Pentax®, that analyzes up to 33 measures, proposing normal ranges according to sex). The Spearman correlation test was used, with significance level of 5%.The association between auditory-perceptual assessment of voice and acoustic parameters ...
Tópico(s): Music and Audio Processing
2015 - Elsevier BV | Journal of Voice
Produção Nacional
Revisado por pares
Johan S. Perez Campos, Yaremis Meriño‐Cabrera, Javier G. Mantilla‐Afanador, Graziela Domingues de Almeida Lima, Samuel Lessa Barbosa, Camilo Elber Vital, Rafael de Almeida Barros, Neilier Rodrigues‐Junior, Eugênio E. Oliveira, M. G. A. Oliveira,
Abstract Proteases present in the salivary glands of phytosuccivorous insects are responsible for the initial breakdown of dietary protein into the amino acids necessary for insect growth and development. Here, we characterised the total proteases and trypsin‐like activities in the salivary glands of the Neotropical brown stink bug, Euschistus heros (F.) and used in silico and biochemical approaches to determine the interactions between trypsin‐like enzymes and the soybean Kunitz trypsin inhibitor ( ...
Tópico(s): Entomopathogenic Microorganisms in Pest Control
2021 - Wiley | Annals of Applied Biology
Patrícia Santos de Souza Delfini, Caroline Dombi-Barbosa, Felipe Lessa da Fonseca, Carlos Mendes Tavares, Alberto Olavo Advicula Reis,
INTRODUÇÃO: os Centros de Atenção Psicossocial Infantojuvenil (CAPSi) constituem ponta de lança das ações da Reforma Psiquiátrica Brasileira e têm por finalidade o atendimento de crianças e adolescentes com transtornos psíquicos graves. O objetivo é caracterizar o perfil dos usuários de um CAPSi, considerando sexo, idade, hipótese diagnóstica, origem do encaminhamento, inserção escolar e motivo de consulta. MÉTODO: por meio de um protocolo, foram coletados dados da totalidade de prontuários ativos ...
Tópico(s): Health, Nursing, Elderly Care
2009 - UNIVERSIDADE DE SÃO PAULO | Journal of Human Growth and Development
Produção Nacional
Revisado por pares
Paulo José Bastos Barbosa, Ínes Lessa, Naomar de Almeida Filho, Lucélia Batista Neves Cunha Magalhães, Jenny Araújo,
To identify and propose the optimal waist circumference cut-off points (WCp) for the diagnosis of central obesity (CO) in a Brazilian population, so as to compare these cut-off points with those recommended by the ATPIII (WC-ATPIII), and to estimate the difference in prevalence rates of metabolic syndrome (MS) using the two criteria.Cross-sectional study conducted in a population subgroup of 1439 adults in the city of Salvador, Brazil. ROC curves of waist circumference (WC) were plotted to identify diabetes ...
Tópico(s): Nutritional Studies and Diet
2006 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Mariana Jardim Azambuja, Márcia Radanovic, Mônica Santoro Haddad, Carla Cristina Adda, Egberto Reis Barbosa, Letı́cia Lessa Mansur,
Language alterations in Huntington's disease (HD) are reported, but their nature and correlation with other cognitive impairments are still under investigation. This study aimed to characterize the language disturbances in HD and to correlate them to motor and cognitive aspects of the disease. We studied 23 HD patients and 23 controls, matched for age and schooling, using the Boston Diagnostic Aphasia Examination, Boston Naming Test, the Token Test, Animal fluency, Action fluency, FAS-COWA, the Symbol ...
Tópico(s): Mitochondrial Function and Pathology
2012 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
... of traditionalist movement), thesis defended by Luiz Carlos Barbosa Lessa during the I Traditionalist Congress, in 1954, still ... sociological influence of the School of Chicago in Barbosa Lessa’s ideas. For this, it’s necessary to ...
Tópico(s): Urban Development and Societal Issues
2011 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Esboços histórias em contextos globais
Produção Nacional
Revisado por pares
Marília Lessa de Vasconcelos Queiroz, José Antônio Delfino Barbosa Filho, Daniel Albiero, Daniel de Freitas Brasil, Rafaela Paula Melo,
A preocupação com o bem-estar dos animais de produção tem sido muito debatida no meio acadêmico. Contudo, para que o bem-estar animal seja aplicado amplamente nas propriedades rurais é necessário que haja demanda dos consumidores por este produto diferenciado. Diante disso, o principal objetivo deste trabalho foi avaliar o nível de conhecimento dos consumidores de produtos de origem animal, de Fortaleza, Ceará, sobre o bem-estar dos animais de produção e sua disposição em pagar por produtos que ...
Tópico(s): Agricultural and Food Sciences
2014 - UNIVERSIDADE FEDERAL DO CEARÁ | Ciência Agronômica/Revista ciência agronômica
Produção Nacional
Revisado por pares
Mariana Jardim Azambuja, Mônica Santoro Haddad, Márcia Radanovic, Egberto Reis Barbosa, Letı́cia Lessa Mansur,
Verbal fluency tasks have been identified as important indicators of executive functioning impairment in patients with frontal lobe dysfunction. Although the usual evaluation of this ability considers phonologic and semantic criteria, there is some evidence that fluency of verbs would be more sensitive in disclosing frontostriatal physiopathology since frontal regions primarily mediate retrieval of verbs. Huntington's disease usually affects these circuitries.To compare three types of verbal fluency ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2007 - Associação Neurologia Cognitiva e do Comportamento | Dementia & Neuropsychologia
Produção Nacional
Revisado por pares
Alynne da Silva Barbosa, Matheus Lessa Cardozo, Laís Verdan Dib, Ana Beatriz Monteiro Fonseca, Cláudia Maria Antunes Uchôa, Otílio Machado Pereira Bastos, Maria Regina Reis Amendoeira,
The aim of the present study was to evaluate the growth rate of Balantidium coli in three xenic media cultures. Between 2013 and 2015, 10 B. coli isolates obtained from feces of Cynomolgus macaques, and 30 isolates from feces of pigs were studied. An inoculum of 500 trophozoites was transferred to tubes containing LES, TYSGM-9 and Pavlova media. These cultures were evaluated at incubation times of 24, 48, 72 and 96 hours. In most of strains analyzed wasn't showed significant difference in the growth ...
Tópico(s): Amoebic Infections and Treatments
2018 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Produção Nacional
Revisado por pares
Douglas Villela de Oliveira Lessa, Rodrigo Costa Portilho-Ramos, Catia F Barbosa, Aline Roberti da Silva, André Belem, Bruno Turcq, Ana Luíza Spadano Albuquerque,
The distribution of planktonic foraminifera in box-core tops under the influence of a western boundary upwelling system along the southeastern Brazilian continental margin was examined to evaluate the similarity percentage (SIMPER) and to create a biofacies model for paleoenvironmental applications. Species associated with warm and oligotrophic water were distributed in the Rio de Janeiro sector of the Campos Basin, while productive water species were most abundant in the Rio de Janeiro sector of ...
Tópico(s): Marine and coastal ecosystems
2014 - Elsevier BV | Marine Micropaleontology
Produção Nacional
Revisado por pares
Renata Moraes Bielemann, Bernardo Lessa Horta, Silvana Paiva Orlandi, Thiago Gonzalez Barbosa-Silva, Marı́a Cristina González, Maria Cecília Formoso Assunção, Denise Petrucci Gigante,
Lean mass (LM) is an important parameter in clinical outcomes, which highlights the necessity of reliable tools for its estimation. The adductor pollicis muscle thickness (APMT) is easily accessible and suffers minimal interference from the adjacent subcutaneous fat tissue.To assess the relationship between the APMT and LM in a sample of Southern Brazilian adults.Participants were adults from the 1982 Pelotas (Brazil) Birth Cohort. LM was measured by dual energy X-ray absorptiometry (DXA). LM and lean ...
Tópico(s): Frailty in Older Adults
2015 - Elsevier BV | Clinical Nutrition
Produção Nacional
Revisado por pares
José Antônio Delfino Barbosa Filho, Marília Lessa Vasconcelos Queiroz, Daniel de Freitas Brasil, Frederico Márcio Corrêa Vieira, Iran José Oliveira da Silva,
The objective of this study was to characterize the microclimatic profile of broiler transport trucks under commercial conditions, in the summer, by continuous monitoring of environmental variables (temperature and air relative humidity). Three loads were monitored from farm to slaughterhouse, considering factors such as distance and day periods (morning, afternoon, and night). To obtain the profile of the environmental variables during journey, data loggers, that determined the microclimate to which ...
Tópico(s): Effects of Environmental Stressors on Livestock
2014 - Sociedade Brasileira de Engenharia Agrícola | Engenharia Agrícola
Produção Nacional
Revisado por pares
Henderson Castelo Sousa, Geocleber Gomes de Sousa, Paulo Bumba Chiumbua Cambissa, Carla Ingryd Nojosa Lessa, Geovana Ferreira Goes, Fred Denílson Barbosa da Silva, Fernanda da S. Abreu, Thales Vinícius de Araújo Viana,
ABSTRACT Semi-arid regions present the inherent problem of accumulation of salts in the soil due to the use of brackish water for irrigation, and water deficit compromises the growth and physiological indices of crops. This study evaluated the effect of salt and water stress on growth and gas exchange in the zucchini cv. Caserta crop. The study was conducted at the University of International Integration of Afro-Brazilian Lusophony, Redenção, Ceará State, Brazil. The experimental design was completely ...
Tópico(s): Soil Management and Crop Yield
2022 - UNIVERSIDADE FEDERAL DE CAMPINA GRANDE | Revista Brasileira de Engenharia Agrícola e Ambiental
Produção Nacional
Revisado por pares
Verônica Aparecida Faustino, Rafael de Almeida Barros, Neilier Junior, Samuel Lessa Barbosa, Camilo Elber Vital, Felipe Lopes da Silva, Yaremis Meriño‐Cabrera, Wellington G. Campos, Humberto Josué de Oliveira Ramos, Maria Goreti de Almeida Oliveira,
Tópico(s): Insect-Plant Interactions and Control
2021 - Springer Science+Business Media | Phytoparasitica
Gilmar Reis, Eduardo Augusto dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Vitoria Helena de Souza Campos, Thiago Santiago Ferreira, Castilho Vitor Quirino dos Santos, Ana Maria Ribeiro Nogueira, Ana Paula Figueiredo Guimaraes Almeida, Leonardo Cançado Monteiro Savassi, Adhemar Dias de Figueiredo Neto, Carina Bitarães, Aline Cruz Milagres, Eduardo Diniz Callegari, Maria Izabel Campos Simplicio, Luciene Barra Ribeiro, Rosemary Oliveira, Ofir Harari, Lindsay A. Wilson, Jamie I. Forrest, Hinda Ruton, Sheila Sprague, Paula McKay, Christina M. Guo, Gordon Guyatt, Craig R. Rayner, David R. Boulware, Nicole Ezer, Todd C. Lee, Emily G. McDonald, Mona Bafadhel, Christopher Butler, Josue Rodrigues Silva, Mark Dybul, Edward J. Mills, Gilmar Reis, Eduardo Augusto dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Castilho Vitor Quirino dos Santos, Ana Maria Ribeiro Nogueira, Ana Paula Figueiredo Guimaraes Almeida, Adhemar Dias de Figueiredo Neto, Leonardo Cançado Monteiro Savassi, Luciene Barra Ribeiro, Maria Izabel Campos Simplicio, Thiago Santiago Ferreira, Vitoria Helena de Souza Campos, Lehana Thabane, Jamie I. Forrest, Edward J. Mills, D. William Cameron, James Orbinski, Sonal Singh, Kristian Thorlund, Jonas Häggström, Heloísa A. Costa, Nayara S. Drumont, Stephanny Kelvyn Bessa, João V.B. Vieira, Vania R Campos, Rosemary Oliveira, Lineria HM Suterio, Josue Rodrigues Silva, Adelino de melo Freire, Ana Carolina Fialho Dias Rocha, Ana Paula de Faria Gonçalves, Andressa França, Carlos Eduardo Dias Igídio, Igor César de Oliveira Sousa, Iracema Luisa Quintino de Carvalho, Larissa Maria Manini Benavides, Patrícia de Oliveira Pereira, Phelipy Marques de Sousa, Sabrina de Almeida Lima, Silvia Helena Sousa Pietra Pedroso, Snaydia Viegas Resende, Wellington da Silva Rocha, Thamiris Caldeira Alves, Aline Lúcia de Jesus Martins, Amanda Gouvêa Mesquita, Amanda Larissa Alves Mendes, Anna Beatriz Oliveira Mendes, Anna Clara de Jesus Oliveira, Carolina Couto de Azevedo Cysne, Clara Bensemann Gontijo Pereira, Cecília Campos Siqueira, Ednilson Barbosa Dias, Emanuelle Cristina Soares Gonçalves, Fernanda Leal Guimarães, Flavio E Giorgeto, Gabriel Torga Saade Rodrigues, Gislânia Neres de Sousa, Júlia Campos de Rezende, Júlia Diniz Assis Moreira, Isabela Canabrava Soares, João Victor Barbosa Silveira, Joselaine Gomes de Souza, Juliana Marques Santos Ferreira, Kênia Sthéfhane Guimarães Gonçalves, Laura Campos Oliveira, Layane Maria de Almeida, Letícia Campos Siqueira, Letícia de Fátimas Costa, Lorena Gabrielle Miranda Maciel, Lorena Giovanna Silva Peixoto, Lorena Mesquita Alves, Luana Rosa Rodrigues, Leonardo Silva de Almeida, Marcela Luíza Amaral Resende Lara, Luíza Lanna França Reis, M. Horacio, Maria Eduarda Martins Soares, Maria Luiza Magalhães Parreiras, M. Siqueira, Mariana Cristina Flores Mariano, Marina Guimarães Bragatto, Matheus Andrade Almeida e Silva, Mayra Estefane Silva dos Santos, Mirele Augusta Batista Ribeiro, Nayara Santos Drumond, Pedro Hosken Fernandes Guimarães, Pollyana Maria Silva Diniz, Roberta Dumont Paiva Lopes, Rosemary Oliveira, Stephanny Kelvyn Bessa, Sheila Soares Anselmo, Tainara Silva Vieira, Tatiana Aparecida Gomes da Silva, Thais Campos Siqueira, Vânia Regina Carmo, Vitor Augusto Lima do Vale, Vitor Vilaça Oliveira, Wedsley Sander Lopes dos Santos, Aline Daniele de Almeida Abreu, Bernardo Saraiva Resende de Camargos, Camila Araújo Heringer, Daniel Jacinto Mendonça Filho, Eriane Damasia Faria de Almeida Abreu, Felipe augusto Pereira Barnabé, Felipe Alves Vieira, Gabriella Fagundes Carvalho, Higor Gomes Mussi, Hilton Cardoso Arruda Macedo, Igor Bernardes Caciquinho, João Pedro Ribeiro Santos, João Ricardo Garcia Costa, José Lauro Guimarães Cardoso, Júlia Berlim de Abreu, Lorena Rodrigues de Carvalho, Lorena Amaral de Oliveira, Luana Rocha Oliveira Matos, Marcela Ferreira Brito, Mariana Cavaliere Batista e Silva, Matheus Lucca Ângelo Costa Rodrigues, Mateus de Oliveira Ferreira, Murilo Passinati Perez, Natalia Batista Zanetti, Rafaela Ribeiro de Almeida, Sarah Jeniffer da Silva Jamar, Sofia Caporalli Barbosa, Sofia Vianna von Bentzeen Rios, Stella Silva Rosa, Thomaz Takashi Ferreira Morimoto, Verônica de Araújo Libânio costa, Vitor Augusto Alves da Silva, Amanda Cypestre Alves Batista, Ana Flávia Gomes Viana, Ângela Rodrigues Vieira Santos, Anna Luiza Ribeiro Flores, Arthur Guimarães Rodrigues Dutra, Bruna Luiza Maia, Clarisse Lourdes Nadú de Almeida, Daniel Domingues Barbosa, Daniela Medeiros, D Silva, Diuly Ane Faria Rezende, Felipe Menezes Andrade, Fernanda Rúbia Batista, Gabriela Ferreira Reis, Giovane Carvalho Constantino Ferreira de Paula, Geovani de Araújo Júnior, Henrique Amaral Fonseca Pires, Jéssica Aguilar da Silva, Isabela Lovatti Rovetta, Júlia Silva Rangel, Júlia Lima Soares de Paula, Juliana de Oliveira Costa, Lucas Júnio da Silva, Luiz Gustavo Fernandes Dias, Lívia Francino Oliveira, Lucas Rodrigues Pereira Barros, Lucas de Souza Gontijo Pessoa, Lucas Klier Silva, Maria Luísa Lara Lanza Stabile, Mariana da Rocha Assis Pinto, Nicholas Vanzin Cunha, Paloma Alister Vilela da Silva, Rafael Silva Rodrigues Soares, Thais Gomes de Oliveira, Victor Oliveira de Araújo, Wesley Costa Arcanjo, A Vanetti, Ana Carolina Araújo Lage Santos, Ariade Gomes Freitas, Felipe Viana Santos, Fernanda Freitas Pinheiro, Fernanda Perez Rocha, Filipe Viana Santos, Giulia de Jesus Marcolino, Humberto Drumond Filho, Isabela Gontijo Mendonça, Isadora Gomides Faria, José Victor Mendes Milhomem, Larissa Milagres Mol, Letícia de Fátima Costa, Marcelo Bernardes Rocha Júnior, Maria Constâncio Miranda, Nathália Euclides Gonçalves, Suzana Cristina Ricco, Thiago Araújo do Nascimento, Amanda Luiza do Espírito Santo Pinheiro, Ana Carolina Matos Ferreira, Ana Caroline Santos Silva, Ana Luiza Silva Taveira, Bruno Victor de Souza Lima, Débora Siqueira Diana, Emanuela Pontes Pereira Silveira, Francisca Lina Campos Gonçalves, Gabriel C. Costa, Geraldo César Barroso de Souza, Guilherme Aurelio D'Oliveira Alves, Isadora Luiza Teixeira Neto, Jordanna Porto Inácio, J. Silverio, Lara Silveira Marques, Larissa Martins do Nascimento, Larissa Oliveira Moreira, Lorena Luiza Soares de Oliveira, Lucas Eduardo Lessa Mussi, Lucas Medeiros Ruas, Luiza Nogueira Assis Barbosa, Luiz Otávio de Sousa, Marcelo Rodrigues da Costa Fernandes, Maria Eduarda Guimarães de Souza, Maria Thereza Figueiredo Bélem Calazans, Mariana Rodrigues Marinho de Bastos, Pedro Henrique Arcanjo Alvarenga, Quimberli Vassinave Cujuí, Rafaela Valadares Diniz, Rafael Cota Andrade Ferreira de Souza, Rita de Cássia Silva, Vinícius Alves Corrêa, Vinícius Carvalho de Oliveira, Vitória Aparecida Cunha, Viviane Costa Santos, Ana Paula Figueiredo Guimaraes Almeida, Ana Paula Guimarães Alves de Carvalho, Antônio Henrique Batista Jorge, Artur Pimenta Ribeiro, Elisângela Santos Sena, Cleide Rocha Veloso, Gonçalvino Eleutério Murta, Inara Maria Gomes Cardoso, João Warley Alves, Jorge Fernando Rocha Veloso, Joyce Souto Barbosa Pimenta de Figueiredo, Karolina Campos Sampaio Lopes, Larissa Vieira Souza, Loren Montanha Costa, Ludimila Pereira de Souza, Maria de Fátima César Lima, Maria Izabel Silveira Gonçalves, Marizete Gislaine Mendes, Mayra Darlliane Loiola Silva, Raissa Rocha e Fonseca, Samuel de Oliveira, Thiago Rodrigues Ferro, Aline Cruz Milagres, Ana Carolina Aguiar Estevam, Ana Martins de Oliveira, André Henrique de Sousa Oliveira, Carina Bitarães, Carla Stefany Oliveira França, Hayka K. Rodrigues Freire, Laís Aparecida dos Reis Gama, Laylla Michelle Pereira, Luciléia Alcântara Gomes e Silva, Patrícia Santana Assis, Regiane Aparecida de Andrade, Thaís de Paula Ferreira da Silva, Thiago de Alcântara César, Adriana Marcos Mendes Rabelo, Aline do Carmo Rosa, Ana Paula Vilas Boas Wherberth, André Gustavo Pinto de Souza, André Luiz Souza Gomes,
Background: Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with COVID-19. Objective: To determine whether the combination of fluvoxamine and inhaled budesonide would increase treatment effects in a highly vaccinated population. Design: Randomized, placebo-controlled, adaptive platform trial. (ClinicalTrials.gov: NCT04727424) Setting: 12 clinical sites in Brazil. Participants: Symptomatic adults ...
American College of Physicians