Produção Nacional
Revisado por pares
Wendel José Teles Pontes, Eraldo Lima, Erivelton Gonçalves da Cunha, Pedro Magno Teixeira de Andrade, Ailton Pinheiro Lôbo, Reginaldo Barros,
Recognition and acceptance of a suitable host plant by phytophagous insects requires the integration of visual, physical and chemical cues. The present study investigates the host cues that a specialist insect integrates to optimize oviposition decisions and whether these cues are weighted in a specific way. The study also determines whether the tomato fruit borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae), an important pest on Solanaceae in Brazil, shows a preference for oviposition ...
Tópico(s): Insect and Pesticide Research
2010 - Wiley | Physiological Entomology
Produção Nacional
Revisado por pares
Carolina Lôbo de Almeida Barros, Ana Luíza Lima Sousa, Brunella Mendonça Chinem, Rafaela Bernardes Rodrigues, Thiago Souza Veiga JARDIM, Sérgio Baiocchi Carneiro, Weimar Kunz Sebba Barroso, Paulo César Brandão Veiga Jardim,
Background: Studies have shown sodium restriction to have a beneficial effect on blood pressure (BP) of hypertensive patients.Objective: To evaluate the impact of light salt substitution for regular salt on BP of hypertensive patients.Methods: Uncontrolled hypertensive patients of both sexes, 20 to 65 years-old, on stable doses of antihypertensive drugs were randomized into Intervention Group (IG -receiving light salt) and Control Group (CG -receiving regular salt).Systolic BP (SBP) and diastolic BP (DBP) ...
Tópico(s): Nutritional Studies and Diet
2014 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Laetitia Koppe, Denise Mafra, Denis Fouque,
... PubMed Scopus (173) Google Scholar, 12.Mafra D. Lobo J.C. Barros A.F. et al.Role of altered intestinal ...
Tópico(s): Gastrointestinal motility and disorders
2015 - Elsevier BV | Kidney International
Produção Nacional
Revisado por pares
Paulo Henrique Santos Andrade, Adriano da Silva Santos, Carlos Adriano Santos Souza, Iza Maria Fraga Lôbo, Wellington Barros da Silva,
Background: The main objective of the present systematic review is to identify potential risk factors for adverse drug reactions (ADRs) through prospective cohort studies in pediatric inpatients. Methods: The data search was done in the following electronic databases PubMed/MEDLINE; Scopus; LILACS and Web of Science from the earliest record until 31 May 2015. Two reviewers independently screened each study and one of them assessed the methodological quality according to the Newcastle–Ottawa scale ...
Tópico(s): Patient Safety and Medication Errors
2017 - SAGE Publishing | Therapeutic Advances in Drug Safety
Produção Nacional
Revisado por pares
Paulo Henrique Santos Andrade, Iza Maria Fraga Lôbo, Wellington Barros da Silva,
The present study aims to identify the risk factors for adverse drug reactions (ADR) in pediatric inpatients.A prospective cohort study in one general pediatric ward in a hospital in Northeast Brazil was conducted in two stages: the first stage was conducted between August 17th and November 6th, 2015, and the second one between March 1st and August 25th, 2016. We included children aged 0-14 years 11 months hospitalized with a minimum stay of 48 hours. Observed outcomes were the ADR occurrence and ...
Tópico(s): Pharmacovigilance and Adverse Drug Reactions
2017 - Public Library of Science | PLoS ONE
João Lobo, Daniela Barros‐Silva, Rui Henrique, Cármen Jerónimo,
Epitranscriptomics has gained ground in recent years, especially after the advent of techniques for accurately studying these mechanisms. Among all modifications occurring in RNA molecules, N6-methyladenosine (m6A) is the most frequent, especially among mRNAs. m6A has been demonstrated to play important roles in many physiological processes and several disease states, including various cancer models (from solid to liquid tumors). Tumor cells’ epitranscriptome is indeed disrupted in a way to promote ...
Tópico(s): Cancer-related molecular mechanisms research
2018 - Multidisciplinary Digital Publishing Institute | Genes
José Pedro Sequeira, Vera Constâncio, Sofia Salta, João Lobo, Daniela Barros‐Silva, Carina Carvalho‐Maia, Jéssica Rodrigues, Isaac Braga, Rui Henrique, Cármen Jerónimo,
Decreased renal cell cancer-related mortality is an important societal goal, embodied by efforts to develop effective biomarkers enabling early detection and increasing the likelihood of curative treatment. Herein, we sought to develop a new biomarker for early and minimally invasive detection of renal cell carcinoma (RCC) based on a microRNA panel assessed by ddPCR.Plasma samples from patients with RCC (n = 124) or oncocytomas (n = 15), and 64 healthy donors, were selected. Hsa-miR-21-5p, hsa-miR-126- ...
Tópico(s): Circular RNAs in diseases
2022 - Multidisciplinary Digital Publishing Institute | Cancers
Produção Nacional
Revisado por pares
Alícia Matijasevich, Iná S. Santos, Mariângela Freitas da Silveira, Marlos Rodrigues Domingues, Aluísio J. D. Barros, Paula Lobo Marco, Fernando C. Barros,
The postnatal period is the ideal time to deliver interventions to improve the health of both the newborn and the mother. However, postnatal care shows low-level coverage in a large number of countries. The objectives of this study were to: 1) investigate inequities in maternal postnatal visits, 2) examine differences in postnatal care coverage between public and private providers and 3) explore the relationship between the absence of maternal postnatal visits and exclusive breastfeeding, use of ...
Tópico(s): Breastfeeding Practices and Influences
2009 - BioMed Central | BMC Public Health
Custódio Lobo Roriz, Lillian Barros, Ana Maria Carvalho, Celestino Santos‐Buelga, Isabel C.F.R. Ferreira,
Pterospartum tridentatum (L.) Willk., Gomphrena globosa L. and Cymbopogon citratus (DC) Stapf. are examples of medicinal plants with antioxidant properties on their own, but that can be improved when mixed. In the present work, the antioxidant activity and phenolic compounds were determined in the infusions prepared from the individual plants, and from mixtures of these plants in different proportions. P. tridentatum > C. citratus > G. globosa was the order observed for antioxidant efficacy, which can ...
Tópico(s): Bee Products Chemical Analysis
2015 - Elsevier BV | Food Chemistry
Custódio Lobo Roriz, Lillian Barros, Ana Maria Carvalho, Isabel C.F.R. Ferreira,
Pterospartum tridentatum (L.) Willk, Gomphrena globosa L., and Cymbopogon citratus (DC.) Stapf are medicinal plants that require a more detailed chemical characterization, given the importance of their consumption as infusions. Therefore, the individual profiles in tocopherols, free sugars, and organic acids were obtained by high performance liquid chromatography (HPLC) coupled to different detectors (fluorescence, refraction index, and photodiode array, resp.). C. citratus revealed the highest content ...
Tópico(s): Medicinal Plants and Bioactive Compounds
2014 - Hindawi Publishing Corporation | International Journal of Food Science
Custódio Lobo Roriz, Lillian Barros, Ana Maria Carvalho, Celestino Santos‐Buelga, Isabel C.F.R. Ferreira,
Pterospartum tridentatum (L.) Willk., Gomphrena globosa L. and Cymbopogon citratus (DC) Stapf. are examples of medicinal plants that demand a more detailed characterization. Therefore, phenolic composition (e.g., phenolic acids and flavonoids) was analyzed by chromatographic and mass spectrometry techniques and the antioxidant activity was also accessed through free radicals scavenging activity, reducing power and inhibition of lipid peroxidation in brain homogenates. C. citratus revealed the highest ...
Tópico(s): Saffron Plant Research Studies
2014 - Elsevier BV | Food Research International
Custódio Lobo Roriz, Lillian Barros, Miguel A. Prieto, Patrícia Morales, Isabel C.F.R. Ferreira,
The present study describes a novel mechanical process for the pigmented parts of Gomphrena globosa L. The effects of the variables of the maceration extraction of betacyanins have not been properly described. Therefore, this study also aims to optimize the conditions that maximize betacyanins extraction from G. globosa as an alternative source. Assisted by response surface methodology, an experimental design was developed for testing the extraction variables (time, temperature, ethanol-water proportion ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2017 - Elsevier BV | Food Chemistry
Custódio Lobo Roriz, Lillian Barros, Miguel A. Prieto, Maria Filomena Barreiro, Patrícia Morales, Isabel C.F.R. Ferreira,
Gomphrena globosa L. is a source of betacyanins, molecules with high colorant power. In order to replace conventional extraction techniques, microwave (MAE) and ultrasound assisted extraction (UAE) processes were optimized by the response surface methodology (RSM) to maximize the recovery of betacyanins from G. globosa. A five-level full factorial design of 24 combinations and 4 replicates was implemented for MAE and UAE. The optimum processing conditions for MAE (t = 8 min; T = 60 °C; Et = 0%; and S/L = 5 g/ ...
Tópico(s): Growth and nutrition in plants
2017 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Revisado por pares
Denise Mafra, Julie Calixto Lobo, A.F. Heras Barros, Laetitia Koppe, Nosratola D. Vaziri, Denis Fouque,
The normal intestinal microbiota plays a major role in the maintenance of health and disease prevention. In fact, the alteration of the intestinal microbiota has been shown to contribute to the pathogenesis of several pathological conditions, including obesity and insulin resistance, among others. Recent studies have revealed profound alterations of the gut microbial flora in patients and animals with chronic kidney disease (CKD). Alterations in the composition of the microbiome in CKD may contribute ...
Tópico(s): Gastrointestinal motility and disorders
2014 - Future Medicine | Future Microbiology
Produção Nacional
Revisado por pares
F. A. de Lobo, M. P. de Barros, Higo J. Dalmagro, Ândrea Carla Dalmolin, Walter Esfrain Pereira, É. C. de Souza, George L. Vourlitis, C. E. R. Ortíz,
A few errors in Table 3, equations 14,16, 18, 25, 29, and 38, and two supplementary files (ESM4 and ESM9) were found in the above-mentioned paper.The corrected table and equations are published here.However, these errors do not compromise the discussion and analysis in the paper.
Tópico(s): Remote Sensing in Agriculture
2014 - Institute of Experimental Botany of the Czech Academy of Sciences | Photosynthetica
F. A. de Lobo, M. P. de Barros, Higo J. Dalmagro, Ândrea Carla Dalmolin, Walter Esfrain Pereira, É. C. de Souza, George L. Vourlitis, C. E. R. Ortíz,
In this study, we presented the most commonly employed net photosynthetic light-response curves (P N/I curves) fitted by the Solver function of Microsoft Excel. Excel is attractive not only due to its wide availability as a part of the Microsoft Office suite but also due to the increased level of familiarity of undergraduate students with this tool as opposed to other statistical packages. In this study, we explored the use of Excel as a didactic tool which was built upon a previously published paper ...
Tópico(s): Leaf Properties and Growth Measurement
2013 - Institute of Experimental Botany of the Czech Academy of Sciences | Photosynthetica
Márcia Seiscento, Fernando Augusto Fluza de Melo, Jorge Ide Neto, Ana Maria Lobo Noronha, Jorge Barros Afiune, Tomiko Inomata, Maria Luíza Cruz,
pregnant patients, and those with renal failure were excluded from the study. Evaluation extended to twelve months after completion of treatment. Results: 70 patients with mean age of 37 years, 42 male, 44 caucasian, and 26 non-caucasian (two orientals), average duration of the condition of four years, and bilateral cavitary lesions in 55 (78.6%). Resistance to two drugs in 28.6%, 51.4% to three drugs, and 20% to four drugs. The most frequent risk predictor factor for MRTB was abandonment (54.3%) followed ...
Tópico(s): Tuberculosis Research and Epidemiology
1997 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal de Pneumologia
Produção Nacional
Revisado por pares
Marta Cristina Corsi de Filippi, Gisele Barata da Silva, V. L. Silva-Lobo, Márcio Vinícius de Carvalho Barros Côrtes, Alessandra Jackeline Guedes de Moraes, A. S. Prabhu,
Rice blast caused by Magnaporthe oryzae has the potential to cause 100% grain yield loss. The objective of this investigation was to identify rhizobacteria showing potential for plant growth stimulation and resistance induction under greenhouse conditions. Bacterial isolates were collected from the rhizosphere of rice plants from soils of Amazon, PA. Soil application with rhizobacteria was done by drenching with bacterial cell suspension before inoculating with virulent isolate of M. oryzae. Mass ...
Tópico(s): Plant tissue culture and regeneration
2011 - Elsevier BV | Biological Control
Produção Nacional
Revisado por pares
Alícia Matijasevich, César G. Victora, Aluísio J. D. Barros, Iná S. Santos, Paula Lobo Marco, Elaine Albernaz, Fernando C. Barros,
We analyzed trends in mortality among infants born to White and to Black or mixed-race women in 3 population-based cohorts representing all births in 1982, 1993, and 2004 in Pelotas, southern Brazil.Births were assessed during daily visits to all maternity hospitals. Maternal skin color was classified by the interviewers as White or Black or multi-racial. We used logistic regression to adjust for socioeconomic, demographic, and health services variables.The mortality rate among infants born to White ...
Tópico(s): Food Security and Health in Diverse Populations
2007 - American Public Health Association | American Journal of Public Health
Produção Nacional
Revisado por pares
Carolina Lôbo De Almeida Barros JACINTHO, Paulo César Brandão Veiga Jardim, Ana Luíza Lima Sousa, Thiago Souza Veiga JARDIM, Weimar Kunz Sebba Barroso,
The difficulty in understanding food labels demands their reformulation. The objective was to elaborate a proposal of nutritional labeling and to compare its understanding with current labels. A cross-sectional study was conducted in 2016. Socioeconomic and health data were collected and questionnaires were used to evaluate reading and comprehension of the current label (Group A) and the proposed label (Group P). Student's t test and chi-square test (p <5%) were applied. A total of 980 consumers participated ...
Tópico(s): Nutritional Studies and Diet
2019 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology
María Eugénia Mata, J.C. Rodrigues da Costa,
... da Rocha.43. Such as Arnaldo Gama, Costa Lobo, Gama Barros, José Anastácio de Figueiredo, Pinheiro Chagas, and Rebelo ...
Tópico(s): Economic Theory and Policy
2013 - Taylor & Francis | Business History
... 746Crossref PubMed Scopus (233) Google Scholar, 36Mafra D. Lobo J.C. Barros A.F. Koppe L. Vaziri N.D. Fouque ...
Tópico(s): Advanced Glycation End Products research
2017 - Elsevier BV | Journal of Renal Nutrition
Custódio Lobo Roriz, Lillian Barros, Miguel A. Prieto, Ana Ćirić, Marina Sokóvić, Patrícia Morales, Isabel C.F.R. Ferreira,
Although less explored than beetroot (Beta vulgaris L.), the flowers of Gomphrena globosa L. are a very suitable source of betacyanins with strong pigmentation features, together with many other desirable bioactive properties. Thus, the aim of this study was to enhance the antimicrobial and antifungal activities of a pigmented extract obtained from G. globosa flowers by ultrasound assisted extraction (UAE). The procedure was supported with the application of the response surface methodology, a robust ...
Tópico(s): Phytochemicals and Antioxidant Activities
2018 - Royal Society of Chemistry | Food & Function
Eurico de Barros Lobo Filho, Danièle Reyx, Irène Campistron, Pierre‐François Casals,
Abstract Some constituents and structures in the mixtures obtained by reaction of oxygen with model compounds of 1,4‐polyisoprene in the presence of phenylhydrazine ( 1 ) could be identified. Accelerated oxidation of monomeric units 2 of 1,4‐polyisoprene by phenyl radical generation (reaction of 1 with oxygen) and in situ decomposition of hydroperoxides, allow to explain the formation of epoxidized and hydroxylated units which were identified. Identification of phenylsubstituted alcohols and phenyl ketones ...
Tópico(s): Synthesis and properties of polymers
1985 - Wiley | Die Makromolekulare Chemie
Produção Nacional
Revisado por pares
Hudson Zanin, Paul May, Anderson Oliveira Lobo, Eduardo Saito, João Paulo Barros Machado, Guilherme Martins, V.J. Trava-Airoldi, E.J. Corat,
We report the effect of incorporation of multi-walled carbon nanotubes (MWCNT) on the mechanical, structural, optical and electrochemical properties of diamond-like carbon (DLC) thin films. The DLC/MWCNT hybrid composite was deposited onto stainless steel and quartz substrates by plasma enhanced chemical vapor deposition at low temperature (∼100°C). Raman spectra of DLC/MWCNT film have characteristics from both DLC and MWCNT. The optical bandgap energy decreases with the incorporation of nanotubes. ...
Tópico(s): Force Microscopy Techniques and Applications
2014 - Institute of Physics | Journal of The Electrochemical Society
Produção Nacional
Revisado por pares
Ana Roberta Pati Pascom, Clarissa Habckost Dutra de Barros, T Lobo, Elisiane Nelcina Pasini, Regina Aparecida Comparini, Fábio Mesquita,
Early diagnosis of infections with human immunodeficiency virus (HIV) is needed - especially among key populations such as sex workers, transgender people, men who have sex with men and people who use drugs.The Brazilian Ministry of Health developed a strategy called Viva Melhor Sabendo ("live better knowing") to increase HIV testing among key populations. In partnership with nongovernmental organizations (NGOs), a peer point-of-care testing intervention, using an oral fluid rapid test, was introduced ...
Tópico(s): Sex work and related issues
2016 - World Health Organization | Bulletin of the World Health Organization
Natália Martins, Custódio Lobo Roriz, Patrícia Morales, Lillian Barros, Isabel C.F.R. Ferreira,
Worldwide consumers seek most delightful and appealing foodstuffs, at the same time they require safer, more nutritious and healthier products. Color is one of the most important organoleptic attributes that directly affects consumers' acceptance and food selection. The present report aims to provide an extensive approach to the field of food (natural/synthetic) colorants, namely those who are currently allowed with established acceptable daily intake (ADI). It also describes the biotechnological ...
Tópico(s): Consumer Attitudes and Food Labeling
2016 - Elsevier BV | Trends in Food Science & Technology
Natália Martins, Custódio Lobo Roriz, Patrícia Morales, Lillian Barros, Isabel C.F.R. Ferreira,
Organoleptic characteristics largely determine food acceptance, selection, and subsequent consumption.
Tópico(s): Pharmacology and Obesity Treatment
2017 - Royal Society of Chemistry | Food & Function
João Lobo, Catarina Guimarães‐Teixeira, Daniela Barros‐Silva, Vera Miranda‐Gonçalves, Vânia Camilo, Rita de Cássia Avellaneda Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique, Cármen Jerónimo,
Novel treatment options are needed for testicular germ cell tumor (TGCT) patients, particularly important for those showing or developing cisplatin resistance, the major cause of cancer-related deaths. As TGCTs pathobiology is highly related to epigenetic (de)regulation, epidrugs are potentially effective therapies. Hence, we sought to explore, for the first time, the effect of the two most recently FDA-approved HDAC inhibitors (HDACis), belinostat and panobinostat, in (T)GCT cell lines including those ...
Tópico(s): Protein Degradation and Inhibitors
2020 - Multidisciplinary Digital Publishing Institute | Cancers
Vera Miranda‐Gonçalves, João Lobo, Catarina Guimarães‐Teixeira, Daniela Barros‐Silva, Rita de Cássia Avellaneda Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique, Cármen Jerónimo,
Germ cell tumors (GCTs) are developmental cancers, tightly linked to embryogenesis and germ cell development. The recent and expanding field of RNA modifications is being increasingly implicated in such molecular events, as well as in tumor progression and resistance to therapy, but still rarely explored in GCTs. In this work, and as a follow-up of our recent study on this topic in TGCT tissue samples, we aim to investigate the role of N6-methyladenosine (m6A), the most abundant of such modifications ...
Tópico(s): Cancer-related molecular mechanisms research
2021 - BioMed Central | Journal of Experimental & Clinical Cancer Research