Lena Hell, Kristina Lurger, Lisa‐Marie Mauracher, Ella Grilz, Christina Maria Reumiller, Georg Schmidt, Huriye Ercan, Silvia Koder, Alice Assinger, José Basílio, Johanna Gebhart, Cihan Ay, Ingrid Pabinger, Maria Zellner,
Patients with antiphospholipid syndrome (APS) are at high risk of developing venous and arterial thromboembolism (TE). The role of platelets in the pathogenesis of these prothrombotic conditions is not yet fully understood. The aim of this study was to gain mechanistic insights into the role of platelets in APS by comparing the platelet proteome between lupus anticoagulant (LA)-positive patients with (LA+ TE+) and without a history of TE (LA+ TE-) and healthy controls. The platelet proteome of 47 patients ...
Tópico(s): Extracellular vesicles in disease
2020 - Springer Nature | Experimental & Molecular Medicine
Jorge Fernando Topete-Reyes, Javier Soto-Vargas, Marı́a Cristina Morán-Moguel, Ingrid Patricia Dávalos‐Rodríguez, E.L. Chávez‐González, Ignacio Garcı́a-De La Torre, Renato Parra‐Michel, Miguel Medina‐Pérez, Basilio Jalomo‐Martínez, Mario Salazar-Páramo,
The angiotensin (Ang)-converting enzyme (ACE) insertion/deletion (I/D) polymorphism determines Ang II levels, but its relationship with lupus nephritis (LN) in different populations is controversial.To describe the allelic and genotypic distribution of the I/D polymorphism in Mexican mestizos with LN and assess an association with histological classes.We included 24 patients with systemic lupus erythematosus (SLE) without nephropathy, 41 with LN, 144 healthy subjects, and 36 with primary glomerulonephritis ( ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2012 - Taylor & Francis | Immunopharmacology and Immunotoxicology
Joseph F. Speyer, Péter Lengyel, Carlos Basilio,
Tópico(s): Vasculitis and related conditions
1962 - National Academy of Sciences | Proceedings of the National Academy of Sciences
M Cuchacovich, Federica Solanes, Gonzalo Díaz, Tomás Cermenati, Samuel Avila, Juan Verdaguer, Juan Ignacio Verdaguer, Cristián Carpentier, Juan Stopel, Basilio Rojas, Traipe Leonidas, Patricia Gallardo, Francisca Sabugo, Mario Zanoli, Guillermo Merino, Francisco Villarroel,
Purpose: To prospectively compare 2 immunosupressive regimens in patients with active Vogt-Koyanagi-Harada disease in spite of systemic glucocorticoid treatment.Methods: Forty-four patients were diagnosed between 1998 and 2005. Twenty-one developed chronic intraocular inflammation in spite of glucocorticoid treatment and were randomized to receive either prednisone and azathioprine (AZA) (n = 12) or prednisone and cyclosporine (CyA) (n = 9).Results: In the AZA group Tyndall score decreased from 1.21 ± 1.10 ...
Tópico(s): Ocular Infections and Treatments
2010 - Taylor & Francis | Ocular Immunology and Inflammation
Ana K. Luchtenberg, Alana C. Basilio, Bárbara L. Charneski, Amanda Poltronieri, Brenda Martins Fernandes, Ana Lúcia Figueiredo Sarquis,
tentamos, no decorrer de um ano, alcançar uma comunidade distante e carente com
Tópico(s): Calpain Protease Function and Regulation
2019 - | Jornal Paranaense de Pediatria
Ernestina Santos, Ana Luísa Rocha, Vanessa Oliveira, Daniela Ferro, Raquel Samões, Ana Paula Sousa, Sónia Figueiroa, Teresa Mendonça, Pedro Abreu, Joana Guimarães, Raquel Sousa, Cláudia Melo, Inês Correia, João Durães, Lívia Sousa, João Ferreira, João de Sá, Filipa Sousa, Marta Sequeira, Ana Sofia Correia, Ana André, Carlos Basílio, Marta Arenga, Irene Mendes, Inês Brás Marques, Sandra Perdigão, Helena Felgueiras, Ivânia Alves, Filipe Correia, Cândida Barroso, Armando Morganho, Cátia Carmona, Filipe Palavra, Mariana Santos, Vasco Salgado, Adelaide Palos, Hipólito Nzwalo, Ângela Timóteo, Rui Guerreiro, Luís Isidoro, Daniela Boleixa, Paula Carneiro, Esmeralda Neves, Ana Silva, Guilherme Gonçalves, Maria Isabel Leite, María José Sá,
Neuromyelitis optica spectrum disorder (NMOSD) is a rare disorder in which astrocyte damage and/or demyelination often cause severe neurological deficits.To identify Portuguese patients with NMOSD and assess their epidemiological/clinical characteristics.This was a nationwide multicenter study. Twenty-four Portuguese adult and 3 neuropediatric centers following NMOSD patients were included.A total of 180 patients met the 2015 Wingerchuk NMOSD criteria, 77 were AQP4-antibody positive (Abs+), 67 MOG- ...
Tópico(s): Systemic
2021 - Elsevier BV | Multiple Sclerosis and Related Disorders
Candela Rodríguez-Pomar, Jesús Pintor, Basilio Colligris, Gonzalo Carracedo,
... such as Sjögren´s Syndrome, rheumatoid arthritis, systemic lupus erythematosus and some drug administration. The treatment of ...
Tópico(s): Advancements in Transdermal Drug Delivery
2017 - Taylor & Francis | Expert Opinion on Pharmacotherapy
Produção Nacional
Revisado por pares
Regina C. Basilio, Francisco Eugênio Loducca, Paulo C. Haddad,
... auto-immune diseases, such as pemphigus vulgaris, systemic lupus erythematosus).The main goal is to prevent or ...
Tópico(s): Streptococcal Infections and Treatments
2004 - Elsevier BV | The Brazilian Journal of Infectious Diseases
Lena Hell, Kristina Lurger, Lisa‐Marie Mauracher, Christina Maria Reumiller, Georg Schmidt, Silvia Koder, Alice Assinger, José Basílio, Johanna Gebhart, Cihan Ay, Ingrid Pabinger, Maria Zellner,
Objectives: Patients with lupus anticoagulants (LA) are at high risk to develop thromboembolism (TE). Previous studies have shown that platelets from LA positive patients show an increased activation status. The aim of this study was to gain deeper insights into the role of platelets in the antiphospholipid syndrome by investigating the platelet proteome of LA positive patients with TE (LA+TE+), LA positive patients without TE (LA+TE-) and of healthy controls.
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2019 - Thieme Medical Publishers (Germany) | Hämostaseologie
M Cuchacovich, Patricio Pacheco, Gonzalo Díaz, Basilio Rojas, Juan O. Stoppel, Guillermo Merino, Juan Ignacio Verdaguer, Juan Verdaguer, Francisco Villarroel,
Role of Azathioprine in steroid resistant non infectious ocular inflammatory diseasesBackground: Topical and systemic steroids are the first line of treatment of non infectious inflammatory ocular disease.Immunosuppresants are reserved as a second line treatment.Aim: To evaluate the role of Azathioprine (AZA) as a coadyuvant immunosuppressive treatment for non infectious ocular inflammatory diseases (OIDs) resistant to systemic steroid therapy in a retrospective, noncomparative interventional case ...
Tópico(s): Systemic
2007 - Q16635223 | Revista médica de Chile
Leonidas Traipe C, Guillermo Conté L, Francisco J Conte S, Santiago Ibáñez L, Patricio Meza R, Basilio Rojas U, Marianela Cuneo, Juan Verdaguer T,
Markers of thrombophilia in patients with retinal vein thrombosis
Tópico(s): Retinal Diseases and Treatments
2005 - Q16635223 | Revista médica de Chile
Produção Nacional
RONIERISSON DE LIMA SARAH, Vitória Severo Jeremias de Ávila, Milena Aguiar de Oliveira, Isabela Pela Freire, Bruno Basilio de Castro Moura,
... prática clínica. Estas condições, como a artrite reumatoide, lúpus eritematoso sistêmico e esclerose sistêmica, podem afetar o ...
Tópico(s): Youth, Drugs, and Violence
2024 - Arche Scientific and Editorial Consultancy | Revista Ibero-Americana de Humanidades, Ciências e Educação
Meritxell Sallés, Sónia Mínguez, Saúl Mario Gelman, Roser Tuneu, Mercè López de Recalde, Basilio Rodríguez, Jaume Trapé, Damià Perich, Ana Muñoz, Sandra Ros, Óscar Bernadich, J Quintero González,
... DNA positive subjects met criteria for erythematosus systemic lupus or systemic sclerosis. The majority were women (88%) ...
Tópico(s): Hypertrophic osteoarthropathy and related conditions
2019 - BMJ | Annals of the Rheumatic Diseases
JORGE ORELLANA R, BASILIO ROJAS U, FRANCISCO VILLARROEL C, PATRICIO ARÁNGUIZ Z,
Corneal autoimmune endotheliopathy as manifestation of intermediate uveitis in childrenBackground: Intermediate Uveitis (IU) is an important cause of uveitis in children.It is considered a chronic intraocular inflammation that mainly affects the anterior vitreous and peripheral retina.Pars Planitis is a subtype of IU, consisting of a white opacity that covers the pars plana and ora serrata plus vitreous condensations in the eye.Corneal endothelium disease is a rare clinical finding associated with ...
Tópico(s): Nephrotoxicity and Medicinal Plants
2008 - Elsevier BV | Revista chilena de pediatría