Kyung Tae Chung, Ying Shen, Linda M. Hendershot,
... Kar2p, the yeast homologue of BiP (27Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ... in the ATPase activity of BiP (27Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ... both Yarrowia lipolytica and Saccharomyces cerevisiae (27Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ... increase the ATPase activity of Kar2p (27Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ... Scholar), perhaps by preventing nucleotide rebinding (34Kabani M. Beckerich J.M. Brodsky J.L. Mol. Cell. Biol. ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2002 - Elsevier BV | Journal of Biological Chemistry
Rabah Redjoul, Anne Le Bouter, Vincent Parinet, Slim Fourati, Sébastien Maury,
... cell transplantation (HSCT).1Redjoul R Le Bouter A Beckerich F Fourati S Maury S Antibody response after ... reduction neutralisation test.1Redjoul R Le Bouter A Beckerich F Fourati S Maury S Antibody response after ... in univariate analyses.1Redjoul R Le Bouter A Beckerich F Fourati S Maury S Antibody response after ... months before vaccination.1Redjoul R Le Bouter A Beckerich F Fourati S Maury S Antibody response after ...
Tópico(s): Immunotherapy and Immune Responses
2021 - Elsevier BV | The Lancet Haematology
Catherine A. McLellan, Deborah A. Raynes, Vince Guerriero,
... FEBS Lett. 2002; PubMed Google Scholar, 9Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ... 6923-6934Crossref Scopus (69) Google Scholar, 10Kabani M. Beckerich J.M. Brodsky J.L. Mol. Cell. Biol. ... shares some sequence homology with HspBP1 (10Kabani M. Beckerich J.M. Brodsky J.L. Mol. Cell. Biol. ...
Tópico(s): Heat shock proteins research
2003 - Elsevier BV | Journal of Biological Chemistry
Anita Boisramé, Jean-Marie Beckerich, Claude Gaillardin,
... of this particle in cotranslational translocation (He, F., Beckerich, J. M., and Gaillardin, C. M.(1992) J. ... of this particle in cotranslational translocation (He, F., Beckerich, J. M., and Gaillardin, C. M.(1992) J. ...
Tópico(s): RNA and protein synthesis mechanisms
1996 - Elsevier BV | Journal of Biological Chemistry
Mehdi Kabani, Jean-Marie Beckerich, Jeffrey L. Brodsky,
... factor for yeast BiP (M. Kabani, J.-M. Beckerich, and C. Gaillardin, Mol. Cell. Biol. 20:6923- ...
Tópico(s): Fungal and yeast genetics research
2002 - Taylor & Francis | Molecular and Cellular Biology
Kang Sup Shim, Christoph Schmütte, Gregory Tombline, Christopher D. Heinen, Richard Fishel,
... ATP binding (for example, see Refs. 29Kabani M. Beckerich J.M. Brodsky J.L. Mol. Cell. Biol. ... PubMed Scopus (119) Google Scholar and 30Kabani M. Beckerich J.M. Gaillardin C. Mol. Cell. Biol. 2000; ...
Tópico(s): CRISPR and Genetic Engineering
2004 - Elsevier BV | Journal of Biological Chemistry
Mehdi Kabani, Jean-Marie Beckerich, Claude Gaillardin,
... reticulum membrane (A. Boisramé, M. Kabani, J. M. Beckerich, E. Hartmann, and C. Gaillardin, J. Biol. Chem. ...
Tópico(s): Signaling Pathways in Disease
2000 - Taylor & Francis | Molecular and Cellular Biology
Lorenzo Canti, Kevin K. Ariën, Isabelle Desombere, Stéphanie Humblet‐Baron, Pieter Pannus, Leo Heyndríckx, Aurélie Henry, Sophie Servais, Évelyne Willems, Grégory Ehx, Stanislas Goriely, Laurence Seidel, Johan Míchiels, Betty Willems, Maria E. Goossens, Yves Béguin, Arnaud Marchant, Frédéric Baron,
... Redjoul et al., 2021aRedjoul R. Le Bouter A. Beckerich F. Fourati S. Maury S. Antibody response after ... Redjoul et al., 2021aRedjoul R. Le Bouter A. Beckerich F. Fourati S. Maury S. Antibody response after ...
Tópico(s): Immunotherapy and Immune Responses
2022 - Cell Press | Cancer Cell
Feng He, Debbie Yaver, Jean-Marie Beckerich, David M. Ogrydziak, C. Gaillardin,
Tópico(s): Bacterial Genetics and Biotechnology
1990 - Springer Science+Business Media | Current Genetics
Feng He, J. M. Beckerich, Vanessa Ribes, David Tollervey, Claude Gaillardin,
Tópico(s): RNA Research and Splicing
1989 - Springer Science+Business Media | Current Genetics
Jean‐Marc Nicaud, Emmanuelle Fabre, J. M. Beckerich, Philippe Fournier, C. Gaillardin,
The alkaline extracellular protease (AEP) gene (XPR2) of the yeast Yarrowia lipolytica was cloned using synthetic oligonucleotide probes based on the N-terminal amino acid sequence of mature AEP. The XPR2 gene codes for a predicted precursor polypeptide of 46903 Da and a mature AEP of 30524 Da. We have increased XPR2 gene copy number by successive integration of XPR2-LYS5 and XPR2-URA3 vectors obtaining strains with one, two and three copies of the XPR2 gene at the XPR2 locus. A disrupting vector ...
Tópico(s): RNA and protein synthesis mechanisms
1989 - Elsevier BV | Journal of Biotechnology
Feng He, J. M. Beckerich, C. Gaillardin,
The yeast Yarrowia lipolytica contains two genes, SCR1 and SCR2, encoding a 7SL RNA associated with a signal recognition particle (SRP). To study 7SL RNA function in vivo we have systematically substituted the two conserved nucleotides G128 and A130 in loop 1 of SCR2-encoded 7SL RNA. All single mutations in either nucleotide have no effect. All double mutations are lethal except for one which results in temperature-sensitive growth. We have studied the synthesis and secretion of an alkaline extracellular ...
Tópico(s): Bacterial Genetics and Biotechnology
1992 - Elsevier BV | Journal of Biological Chemistry
Anita Boisramé, Marion Chasles, Anna Babour, Jean-Marie Beckerich, Claude Gaillardin,
The core component of the translocation apparatus, Sec61p or alpha, was previously cloned in Yarrowia lipolytica. Using anti-Sec61p antibodies, we showed that most of the translocation sites are devoted to co-translational translocation in this yeast, which is similar to the situation in mammalian cells but in contrast to the situation in Saccharomyces cerevisiae, where post-translational translocation is predominant. In order to characterize further the minimal translocation apparatus in Y. lipolytica, ...
Tópico(s): RNA and protein synthesis mechanisms
2002 - The Company of Biologists | Journal of Cell Science
Dominique Swennen, Marie-Françoise Paul, Laurence Vernis, Jean-Marie Beckerich, Alain Fournier, Claude Gaillardin,
Yarrowia lipolytica and Kluyveromyces lactis secretion vectors were constructed and assessed for the expression of heterologous proteins. An anti-Ras single-chain antibody fragment (scFv) coding sequence was fused in-frame to different pre- or prepro-regions, or downstream from a reporter secretory gene (Arxula adeninivorans glucoamylase), separated by a Kex2 protease (Kex2p)-like processing sequence. Both organisms are able to secrete soluble scFv, with yields depending on the nature of the expression ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2002 - Microbiology Society | Microbiology
Gerold Barth, Jean-Marie Beckerich, Ángel Domínguez, Stefan Kerscher, David M. Ogrydziak, Vladimir I. Titorenko, Claude Gaillardin,
The yeast Yarrowia lipolytica has been used for industrial bioconversions since the late 1960's, mainly by the food and chemical industries. The most important process is presently the production of citric acid from rapeseed oil, but Y. lipolytica has also been considered for various other applications, ranging from single cell protein to heterologous proteins production. Several of these procedures have received a GRAS status, which facilitates further applications of this yeast in the food and ...
Tópico(s): Biofuel production and bioconversion
2003 - Springer Science+Business Media | Topics in current genetics
Anna Babour, J. M. Beckerich, C. Gaillardin,
Abstract The UDP‐Glc:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that plays a determining part in the mechanism by which unfolded, partially folded or misfolded glycoproteins are retained into the ER. We have identified an UGT in the yeast Yarrowia lipolytica . This protein, of a predicted molecular weight of 165.7 kDa, is encoded by a 5054 bp coding sequence containing a 643 bp intron at position 682–1323. The N‐terminal part of the protein displays ...
Tópico(s): Cellular transport and secretion
2003 - Wiley | Yeast
Anna Babour, Mehdi Kabani, Anita Boisramé, Jean-Marie Beckerich,
Tópico(s): Transgenic Plants and Applications
2008 - Springer Science+Business Media | Current Genetics
S. Mansour, J. M. Beckerich, Pascal Bonnarme,
The consumption of lactate and amino acids is very important for microbial development and/or aroma production during cheese ripening. A strain of Yarrowia lipolytica isolated from cheese was grown in a liquid medium containing lactate in the presence of a low (0.1x) or high (2x) concentration of amino acids. Our results show that there was a dramatic increase in the growth of Y. lipolytica in the medium containing a high amino acid concentration, but there was limited lactate consumption. Conversely, ...
Tópico(s): Fungal and yeast genetics research
2008 - American Society for Microbiology | Applied and Environmental Microbiology
Sylvie Bazin, Christophe Beckerich, Marie Delaplace,
La LGV est-européenne a été mise en service le 10 juin 2007. Les acteurs économiques des territoires desservis attendent beaucoup de cette arrivée notamment en matière de développement des tourismes urbain et d'affaires. Mais un tel développement n'est pas automatique. C'est l'appropriation collective de l'innovation que constitue la desserte à grande vitesse dans un territoire qui est au coeur de ses effets positifs. En effet, cette appropriation collective constitue une innovation relationnelle ...
Tópico(s): Sharing Economy and Platforms
2010 - Katholieke Universiteit Leuven | BELGEO
Cuiren Chen, K.A. Abdelrahim, Isabelle Beckerich,
The process sensitivity analysis of continuous Ohmic heating process for soup products containing large particulates was performed by use of a validated computer modeling package to determine the critical control factors and their acceptable control ranges under given control targets. The major processing variables investigated included electrical conductivities of carrier fluid and particles, particle thermal diffusivity, surface heat transfer coefficient, particle size, particle concentration, ...
Tópico(s): Ultrasound and Hyperthermia Applications
2010 - Elsevier BV | Journal of Food Engineering
Maja A. Tocilescu, Uta Fendel, Klaus Zwicker, Stefan Kerscher, Ulrich Brandt,
... by PCR mutagenesis. After transformation (23Chen D.-C. Beckerich J.-M. Gaillardin C. Appl. Biochem. Biotechnol. 1997; ...
Tópico(s): Photosynthetic Processes and Mechanisms
2007 - Elsevier BV | Journal of Biological Chemistry
Céline N. Martineau, Jean-Marie Beckerich, Mehdi Kabani,
The yeast Saccharomyces cerevisiae has been used as a model for fungal biofilm formation due to its ability to adhere to plastic surfaces and to form mats on low-density agar petri plates. Mats are complex multicellular structures composed of a network of cables that form a central hub from which emanate multiple radial spokes. This reproducible and elaborate pattern is indicative of a highly regulated developmental program that depends on specific transcriptional programming, environmental cues, ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2007 - Oxford University Press | Genetics
Dominique Swennen, Jean-Marie Beckerich,
Protein secretion is a universal cellular process involving vesicles which bud and fuse between organelles to bring proteins to their final destination. Vesicle budding is mediated by protein coats; vesicle targeting and fusion depend on Rab GTPase, tethering factors and SNARE complexes. The Génolevures II sequencing project made available entire genome sequences of four hemiascomycetous yeasts, Yarrowia lipolytica, Debaryomyces hansenii, Kluyveromyces lactis and Candida glabrata. Y. lipolytica ...
Tópico(s): RNA and protein synthesis mechanisms
2007 - Springer Science+Business Media | BMC Evolutionary Biology
Agnès Hébert, Marie-Pierre Forquin-Gomez, Aurélie Roux, Julie Aubert, Christophe Junot, Valentin Loux, Jean-François Heilier, Pascal Bonnarme, Jean-Marie Beckerich, Sophie Landaud,
Tópico(s): Polyamine Metabolism and Applications
2011 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Sylvie Bazin, Christophe Beckerich, Corinne Blanquart, Marie Delaplace, Lidwine Vandenbossche,
Des projets de lignes a grande vitesse existent dans de nombreux pays. Les acteurs economiques des territoires desservis ou qui le seront, ont eu ou ont de multiples attentes concernant cette desserte qui modifie l'accessibilite de leurs territoires : dynamisme economique, arrivee de nouvelles entreprises et populations, developpement du tourisme, ou de projets immobiliers residentiels et de bureaux autour des gares, etc. La permanence de ces attentes, alors que le mythe des effets structurants des ...
Tópico(s): Urban and Freight Transport Logistics
2011 - CIG Media Group | Recherche Transports Sécurité
Agnès Hébert, Serge Casarégola, Jean-Marie Beckerich,
The evolution of the metabolism of sulfur compounds among yeast species was investigated. Differences between species were observed in the cysteine biosynthesis pathway. Most yeast species possess two pathways leading to cysteine production, the transsulfuration pathway and the O-acetyl-serine (OAS) pathway, with the exception of Saccharomyces cerevisiae and Candida glabrata, which only display the transsulfuration pathway, and Schizosaccharomyces pombe, which only have the OAS pathway. An examination ...
Tópico(s): Yeasts and Rust Fungi Studies
2011 - Oxford University Press | FEMS Yeast Research
Jing Zhang, Kyla M. Smith, Tracey Tackaberry, Xuejun Sun, Pat Carpenter, Melissa D. Slugoski, Morris J. Robins, Lars Peter Nielsen, Ireneusz Nowak, Stephen A. Baldwin, James D. Young, Carol E. Cass,
... Babour A. Barbe V. Barnay S. Blanchin S. Beckerich J.M. Beyne E. Bleykasten C. Boisrame A. ...
Tópico(s): Enzyme-mediated dye degradation
2006 - Elsevier BV | Journal of Biological Chemistry
Sylvie Bazin, Christophe Beckerich, Marie Delaplace, Sophie Masson,
La mise en service de la LGV Est-Européenne (LGV-Est) est prévue pour 2007. Cette ligne devrait modifier les conditions d’accessibilité de certaines villes de la région Champagne-Ardenne à Paris, ainsi qu’à des villes de province reliées au réseau LGV. L’objectif de cet article est d’évaluer les effets potentiels de la LGV-Est sur la cohésion territoriale de la région Champagne-Ardenne. La LGV-Est peut-elle contribuer à renforcer la cohésion territoriale de cette région, aujourd’hui faible, ou au ...
Tópico(s): European Socioeconomic and Political Studies
2006 - | Revue d’Économie Régionale & Urbaine
Agnès Hébert, Marie-Pierre Forquin-Gomez, Aurélie Roux, Julie Aubert, Christophe Junot, Jean-François Heilier, Sophie Landaud, Pascal Bonnarme, Jean-Marie Beckerich,
ABSTRACT Yarrowia lipolytica , located at the frontier of hemiascomycetous yeasts and fungi, is an excellent candidate for studies of metabolism evolution. This yeast, widely recognized for its technological applications, in particular produces volatile sulfur compounds (VSCs) that fully contribute to the flavor of smear cheese. We report here a relevant global vision of sulfur metabolism in Y. lipolytica based on a comparison between high- and low-sulfur source supplies (sulfate, methionine, or cystine) ...
Tópico(s): Fungal and yeast genetics research
2012 - American Society for Microbiology | Applied and Environmental Microbiology
... EMBO J. 8, 2225–2229. 74 He, F., Beckerich, J. M. and Gaillardin, C. (1992). A mutant ...
Tópico(s): Toxin Mechanisms and Immunotoxins
1993 - Wiley | Yeast