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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Dimitrios C. Mastellos, Bruno G. P. Pires da Silva, Benedito Antônio Lopes da Fonseca, Natasha Peixoto Fonseca, Maria Auxiliadora‐Martins, Sara Mastaglio, Annalisa Ruggeri, Marina Sironi, Peter Radermacher, Akrivi Chrysanthopoulou, Panagiotis Skendros, Konstantinos Ritis, Ilenia Manfra, Simona Iacobelli, Markus Huber‐Lang, Bo Nilsson, Despina Yancopoulou, E. Sander Connolly, Cecília Garlanda, Fabio Ciceri, Antonio M. Risitano, Rodrigo T. Calado, John D. Lambris,

Growing clinical evidence has implicated complement as a pivotal driver of COVID-19 immunopathology. Deregulated complement activation may fuel cytokine-driven hyper-inflammation, thrombotic microangiopathy and NET-driven immunothrombosis, thereby leading to multi-organ failure. Complement therapeutics have gained traction as candidate drugs for countering the detrimental consequences of SARS-CoV-2 infection. Whether blockade of terminal complement effectors (C5, C5a, or C5aR1) may elicit similar ...

Tópico(s): SARS-CoV-2 and COVID-19 Research

2020 - Elsevier BV | Clinical Immunology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marília Santos Andrade, Fabiana De Carvalho Koffes, Ana Amélia BeneditoSilva, Antonio Carlos da Silva, Claudio André Barbosa de Lira,

Arm throwing represents a deciding element in handball. Ball velocity, aim accuracy, and dynamic stability of the shoulder are factors that influence throwing effectiveness. The purpose of this study was to examine the influence of muscle fatigue caused by simulated game activities (SGA) on shoulder rotational isokinetic muscle strength, muscle balance and throwing performance, and to examine the relationship between muscle strength and throwing performance. Ten national elite adult handball athletes ...

Tópico(s): Sports injuries and prevention

2016 - BioMed Central | BMC Sports Science Medicine and Rehabilitation

Artigo Brasil Produção Nacional Revisado por pares

Marília Santos Andrade, Claudio André Barbosa de Lira, Rodrigo Luiz Vancini, Alexandre Aparecido de Almeida, Ana Amélia BeneditoSilva, Antonio Carlos da Silva,

To evaluate the external (ER) and internal rotator (IR) muscles' isokinetic peak torque and conventional and functional strength ratios in handball players and controls of different ages. Cross-sectional and descriptive analysis. Exercise Physiology Laboratory. A total of 228 participants (108 athletes and 120 controls) were divided into five groups according to age, ranging from 13 to 36 years old. Isokinetic tests were performed concentrically at 60 and 300 deg s−1 and eccentrically at 300 deg s− ...

Tópico(s): Shoulder and Clavicle Injuries

2013 - Elsevier BV | Physical Therapy in Sport

Artigo Brasil Produção Nacional Revisado por pares

Marília Santos Andrade, Claudio André Barbosa de Lira, Fabiana De Carvalho Koffes, Naryana Mascarin, Ana Amélia BeneditoSilva, Antonio Carlos da Silva,

The purpose of this study was to determine differences in hamstrings-to-quadriceps (H/Q) peak torque ratios evaluated at different angular velocities between men and women who participate in judo, handball or soccer. A total of 166 athletes, including 58 judokas (26 females and 32 males), 39 handball players (22 females and 17 males), and 69 soccer players (17 females and 52 males), were evaluated using an isokinetic dynamometer. The H/Q isokinetic peak torque ratios were calculated at angular velocities ...

Tópico(s): Sports injuries and prevention

2012 - Taylor & Francis | Journal of Sports Sciences

Artigo Brasil Produção Nacional Revisado por pares

Osmair Benedito da Silva, Sérgio Antônio Spínola Machado,

In this work, the reduction reaction of paraquat herbicide was used to obtain analytical signals using electrochemical techniques of differential pulse voltammetry, square wave voltammetry and multiple square wave voltammetry. Analytes were prepared with laboratory purified water and natural water samples (from Mogi-Guaçu River, SP). The electrochemical techniques were applied to 1.0 mol L−1 Na2SO4 solutions, at pH 5.5, and containing different concentrations of paraquat, in the range of 1 to 10 ...

Tópico(s): Electrochemical sensors and biosensors

2012 - Royal Society of Chemistry | Analytical Methods

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paula Renata Lima Machado, Kléber Juvenal Silva Farias, Maira Gabriela Martins Pereira, Patrícia Pereira da Silva de Freitas, Benedito Antônio Lopes da Fonseca,

Kaposi's sarcoma (KS) is a common neoplastic disease in AIDS patients. The aim of this study was to evaluate the frequency of human herpesvirus 8 (HHV-8) infection in human immunodeficiency virus (HIV)-infected patients, with or without KS manifestations and correlate HHV-8 detection with KS staging.Analytic cross-sectional study conducted in a public tertiary-level university hospital in Ribeirão Preto, São Paulo, Brazil.Antibodies against HHV-8 lytic-phase antigens were detected by means of the immunofluorescence ...

Tópico(s): Parvovirus B19 Infection Studies

2015 - Medical Association of São Paulo | Sao Paulo Medical Journal

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Arlene J.M. Caldas, Denise R.C. Silva, Célia C.R. Pereira, Paulo Márcio Sousa Nunes, Benedito P. Silva, Antônio Augusto Moura da Silva, Aldina Barral, Jackson M. L. Costa,

Realizou-se estudo prospectivo com 648 crianças de zero a cinco anos no município da Raposa-MA, de julho/97 a junho/98, com o objetivo de avaliar as características da infecção por L.(L.)chagasi e verificar se existe associação entre desnutrição e infecção assintomática. Utilizou-se questionário com dados socioeconômicos, ambientais e hábitos de vida; realizou-se Intradermorreação de Montenegro(IDRM) com antígeno de L. amazonensis e Enzyme Linked Immunosorbant Assay(ELISA) para detectar infecção, ...

Tópico(s): Trypanosoma species research and implications

2001 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Benedito Rocha Vital, Antônio da Silva Maciel, Ricardo Marius Della Lúcia,

Este experimento teve como objetivo avaliar a resistência de juntas coladas formadas pelas combinações de lâminas provenientes de três posições no tronco da madeira de Eucalyptus grandis, Eucalyptus saligna e Pinus elliottii. Foram empregados adesivos à base de poliacetato de vinila de média e alta viscosidade e resorcinol-formaldeído nas gramaturas de 150 g/m², em face simples para o poliacetato de vinila de média e alta viscosidades e 300 g/m², em face dupla, para o adesivo resorcinólico. O teor ...

Tópico(s): Natural Fiber Reinforced Composites

2006 - Sociedade de Investigações Florestais | Revista Árvore

Artigo Acesso aberto Revisado por pares

Juliana Helena Chávez, Rafael Freitas de Oliveira França, Carlo José Freire Oliveira, Maria Teresa P. de Aquino, Kléber Juvenal Silva Farias, Paula Renata Lima Machado, Thelma Fátima Mattos Oliveira, Jonny Yokosawa, Edson García Soares, João S. Silva, Benedito Antônio Lopes da Fonseca, Luíz Tadeu Moraes Figueiredo,

Rocio virus (ROCV) caused an outbreak of human encephalitis during the 1970s in Brazil and its immunopathogenesis remains poorly understood. CC-chemokine receptor 5 (CCR5) is a chemokine receptor that binds to macrophage inflammatory protein (MIP-1 α). Both molecules are associated with inflammatory cells migration during infections. In this study, we demonstrated the importance of the CCR5 and MIP-1 α, in the outcome of viral encephalitis of ROCV-infected mice. CCR5 and MIP-1 α knockout mice survived ...

Tópico(s): interferon and immune responses

2013 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene

Artigo Brasil Produção Nacional Revisado por pares

Acácia Gonçalves Ferreira Leal, Rodrigo Luiz Vancini, Paulo Gentil, Ana Amélia BeneditoSilva, Antonio Carlos da Silva, Mário Hebling Campos, Marília Santos Andrade, Claudio André Barbosa de Lira,

Purpose The purpose of this paper was to assess the knowledge on sport and exercise science held by a sample of Brazilian physiotherapists, nutritionists and physical educators. Design/methodology/approach A cross-sectional research design was used. The answers given by 1,147 professionals (300 physiotherapists, 705 physical educators and 142 nutritionists) who participated in a qualifying process for a specialization course on exercise physiology were analyzed. Questions were analyzed on maximal ...

Tópico(s): Cardiovascular and exercise physiology

2018 - Emerald Publishing Limited | Health Education

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Janaína Luz Narciso-Schiavon, Leonardo de Lucca Schiavon, Roberto José de Carvalho‐Filho, Juliana P. Sampaio, Philipe Nicolas El Batah, Denize Vieira Barbosa, Maria Lúcia Gomes Ferraz, Antônio Eduardo Benedito Silva,

Although various studies have been published regarding the treatment of chronic hepatitis C (CHC) with peginterferon (Peg-IFN) and ribavirin, little is known regarding the real impact of gender on the characteristics that influence the effectiveness and safety of antiviral treatment for CHC patients. The objective of this study was to evaluate the influence of gender on HCV treatment outcomes.A retrospective analytical study was conducted among selected carriers of CHC genotype 1, who were treated ...

Tópico(s): Hepatitis B Virus Studies

2010 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Mariana Munari Magnus, Danillo Lucas Alves Espósito, Victor Antonio da Costa, Priscila Silva de Melo, Carolina Costa-Lima, Benedito Antônio Lopes da Fonseca, Marcelo Addas‐Carvalho,

Zika, a disease caused by Zika virus infections, has recently emerged and caused outbreaks in many parts of the world. The clinical manifestations of Zika are usually mild, mostly presenting as an exanthematic febrile disease, but on some occasions, it might be associated with microcephaly after intrauterine infection, and Guillain-Barré Syndrome. Zika virus is primarily transmitted by mosquito bites, but other means of transmission have been described, and potential risk for blood transmission ...

Tópico(s): Malaria Research and Control

2018 - Elsevier BV | Hematology Transfusion and Cell Therapy

Artigo Brasil Produção Nacional Revisado por pares

Roberto José de Carvalho‐Filho, Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon, Juliana P. Sampaio, Valéria Pereira Lanzoni, Maria Lúcia Gomes Ferraz, Antonio E. Benedito Silva,

Abstract Background: Recent reports suggest that hepatitis C virus (HCV) carriers with serological markers of prior hepatitis B virus (HBV) infection have more advanced liver fibrosis, irrespective of HBV‐DNA detection. Aims: We sought to assess the prevalence and impact of previous HBV infection in patients with HCV chronic infection. Methods: This cross‐sectional study included hepatitis B surface antigen‐ and human immunodeficiency virus‐negative subjects with positive HCV‐RNA. All patients had ...

Tópico(s): Liver Disease Diagnosis and Treatment

2008 - Wiley | Liver International

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Da Silva, Alexandre H. Lopes, Jhimmy Talbot, Nerry T. Cecílio, Mateus Rossato, Rangel L. Silva, Guilherme R. Souza, Cássia Regina Silva, Guilherme Lucas, Benedito Antônio Lopes da Fonseca, Eurico Arruda, José C. Alves‐Filho, Fernando Q. Cunha, Thiago M. Cunha,

Herpetic neuralgia is the most important symptom of herpes zoster disease, which is caused by Varicella zoster . Nevertheless, the pathophysiological mechanisms involved in herpetic neuralgia are not totally elucidated. Here, we examined the neuroimmune interactions at the sensory ganglia that account for the genesis of herpetic neuralgia using a murine model of Herpes Simplex Virus Type-1 (HSV-1) infection. The cutaneous HSV-1 infection of mice results in the development of a zosteriform-like skin ...

Tópico(s): Dermatology and Skin Diseases

2017 - Society for Neuroscience | Journal of Neuroscience

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Antônio da Silva Maciel, Benedito Rocha Vital, Ricardo Marius Della Lúcia, Alexandre Santos Pimenta,

O objetivo deste trabalho foi avaliar as propriedades de painéis fabricados com partículas de madeira, poliestireno (PS) e polietileno tereftalato (PET). Foram utilizadas três proporções, em relação à massa seca de madeira, de poliestireno (0, 25 e 50%) e duas proporções de PET/PS (5/20 e 10/40%), combinadas com 50, 75 ou 100% de partículas de madeira de Pinus elliottii. Os painéis foram produzidos com adesivos à base de uréia-formaldeído ou de fenol-formaldeído, em três teores (0, 4 ou 6%) e três níveis ...

Tópico(s): Mechanical Behavior of Composites

2004 - Sociedade de Investigações Florestais | Revista Árvore

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luciano Bello Costa, Maria Lúcia Gomes Ferraz, Renata de Mello Perez, Adalgisa S.P. Ferreira, Carla Adriana Loureiro de Matos, Valéria Pereira Lanzoni, Antônio Eduardo Benedito Silva,

There is increasing interest in the identification of factors associated with liver disease progression in patients infected with hepatitis C virus (HCV). We assessed host-related factors associated with a histologically advanced stage of this disease and determined the rate of liver fibrosis progression in HCV-infected patients. We included patients submitted to liver biopsy, who were anti-HCV and HCV RNA positive, who showed a parenteral risk factor (blood transfusion or intravenous drug use), and ...

Tópico(s): Liver Disease and Transplantation

2002 - Elsevier BV | The Brazilian Journal of Infectious Diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Alan Ferreira Leite de Lima, Milton César Costa Campos, Thalita Silva Martins, Guilherme Abadia da Silva, Wildson Benedito Mendes Brito, Luís Antônio Coutrim dos Santos, Ivanildo Amorim de Oliveira, José Maurício da Cunha,

The south of the Brazilian Amazon is one of the largest cattle-producing regions in Brazil, however, most of the pastures are in low fertility soils. Thus, cattle breeders compensate for the low production of pastures, increasing the size of the areas, generating more deforestation and burning. These practices increase the chemical degradation process of Amazonian soils, making them increasingly infertile when improperly managed. With this, the objective of the work was to evaluate the impacts caused ...

Tópico(s): Forest ecology and management

2022 - Nature Portfolio | Scientific Reports

Artigo Brasil Produção Nacional Revisado por pares

Sérgio Marangoni, Marcos Hikari Toyama, Eliane Candiani Arantes, JoséR. Giglio, Carlos A. da Silva, Everardo M. Carneiro, Antonio Ari Gonçalves, Benedito Oliveira,

Highly purified Tityustoxin V (TsTX-V), an a-toxin isolated from the venom of the Brazilian scorpion Tityus serrulatus, was obtained by ion exchange chromatography on carboxymethylcellulose-52. It was shown to be homogeneous by reverse phase high performance liquid chromatography, N-terminal sequencing (first 39 residues) of the reduced and alkylated protein and by polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate and tricine. Following enzymatic digestion, the complete amino ...

Tópico(s): Cardiac electrophysiology and arrhythmias

1995 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - General Subjects

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Roberto Benedito de Paiva e Silva, Antonio Sérgio Ramalho,

A triagem populacional de heterozigotos assintomáticos para fins de orientação genética é um procedimento bastante controvertido, por envolver o risco de rotulação, discriminação, estigmatização, perda de auto-estima e invasão de privacidade. Assim sendo, investigou-se no presente trabalho os efeitos da orientação genética fornecida a indivíduos diagnosticados como heterozigotos do gene da hemoglobina S (heterozigotos AS, portadores do traço falciforme) durante a triagem de doadores de sangue. Foram ...

Tópico(s): Prenatal Screening and Diagnostics

1997 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Antônio Camargo Martins, Thasciany Moraes Pereira, Humberto Oliart-Guzmán, Breno Matos Delfino, Saulo Augusto Silva Mantovani, Athos Muniz Braña, Fernando Luiz Cunha Castelo Branco, José Alcântara Filgueira Júnior, Ana Paula Santos, Alanderson Alves Ramalho, Andréia Silva Guimarães, Thiago Santos de Araújo, Cristieli Sérgio de Menezes Oliveira, Benedito Antônio Lopes da Fonseca, Mônica da Silva-Nunes,

This study aimed to evaluate the prevalence of serum IgG dengue in children in an Amazonian population, to assess the seroconversion rate in 12 months, and to estimate how many seropositive children had a prior clinical diagnosis of dengue. We conducted a population-based study between 2010 and 2011, with children aged 6 months to 12 years that were living in the urban area of a small town in the Brazilian Amazon. The prevalence of IgG antibodies against dengue antigens was determined by indirect ...

Tópico(s): Viral Infections and Vectors

2014 - Hindawi Publishing Corporation | Interdisciplinary Perspectives on Infectious Diseases

Artigo Brasil Produção Nacional Revisado por pares

Silvia Naomi de Oliveira Uehara, Christini Takemi Emori, Patrícia da Silva Fucuta Pereira, Renata de Mello Perez, José Osmar Medina Pestana, Valéria Pereira Lanzoni, Ivonete Sandra Souza e Silva, Antônio Eduardo Benedito Silva, Maria Lúcia Gomes Ferraz,

Abstract Background information regarding histological progression of hepatitis C after renal transplant ( RT x) is scarce. Aims To analyze clinical and laboratory evolution and histological progression of hepatitis C in patients evaluated before and after RT x. Methods Twenty‐two HCV ‐infected patients submitted to liver biopsy pre‐ and post‐ RT x were included. A semiquantitative analysis of necroinflammatory activity and fibrosis staging was performed and the two biopsies were compared. Results ...

Tópico(s): Liver Disease and Transplantation

2012 - Wiley | Clinical Transplantation

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ernesto Antônio Figueiró Filho, Geraldo Duarte, Alzira Amélia Martins Rosa e Silva, Benedito Antônio Lopes da Fonseca, Marisa Márcia Mussi‐Pinhata, Silvana Maria Quintana, Patrícia El Beitune,

OBJETIVO: avaliar os efeitos de drogas anti-retrovirais isoladas e em associação sobre as taxas de fertilidade em ratas prenhes expostas a estes fármacos, bem como o efeito perinatal nas crias. MÉTODOS: foram utilizadas ratas fêmeas prenhes adultas da raça Wistar, pesando inicialmente entre 200 e 230 g. Foram testadas a azidotimidina (AZT), lamivudina (3TC) e nelfinavir (NFV), cujas dosagens foram padronizadas em 10 vezes a dose normalmente utilizada em gestantes, proporcionalmente ao peso dos animais. ...

Tópico(s): Pregnancy and Medication Impact

2002 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia

Artigo Brasil Produção Nacional Revisado por pares

Eduardo Algranti, Elizabete Medina Coeli Mendonça, E.M. DeCapitani, Jefferson Benedito Pires de Freitas, H.C. Silva, Marco Antônio Bussacos,

Abstract Background Production of asbestos‐cement products in Brazil started in the 1940s, peaked in the 60–70s and is still an active industry. This study was designed to assess the non‐malignant effects of asbestos exposure in the asbestos‐cement industry in Brazil. Methods A group of 828 former asbestos‐cement workers enrolled in a cross‐sectional and cohort study of respiratory morbidity, submitted to a detailed occupational history, respiratory symptoms questionnaire, spirometry, PA chest x‐ ...

Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

2001 - Wiley | American Journal of Industrial Medicine

Artigo Brasil Produção Nacional Revisado por pares

Gustavo Pompermaier Garlet, Walter Martins, Benedito Antônio Lopes da Fonseca, Beatriz Rossetti Ferreira, João S. Silva,

Abstract Objective: Inflammatory reactions raised in response to periodontopathogens are thought to trigger pathways of periodontal tissue destruction. We therefore investigated the expression of matrix metalloproteinases (MMPs) and the osteoclastogenic factor receptor activator of nuclear factor‐ κ B ligand (RANKL), their respective tissue inhibitors of metalloproteinases (TIMPs) and osteoprotegerin (OPG) in different forms of human periodontal diseases (PDs), and the possible correlation with the expression ...

Tópico(s): Oral and gingival health research

2004 - Wiley | Journal Of Clinical Periodontology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Paulo Marcos da Matta Guedes, Fredy R. S. Gutierrez, Grace Kelly Silva, Renata Dellalibera-Joviliano, Gerson Jhonatan Rodrigues, Lusiane Maria Bendhack, Anis Rassi, Anis Rassi, André Schmidt, Benedito Carlos Maciel, José Antônio Marin‐Neto, João S. Silva,

Background Myocardium damage during Chagas' disease results from the immunological imbalance between pro- and production of anti-inflammatory cytokines and has been explained based on the Th1–Th2 dichotomy and regulatory T cell activity. Recently, we demonstrated that IL-17 produced during experimental T. cruzi infection regulates Th1 cells differentiation and parasite induced myocarditis. Here, we investigated the role of IL-17 and regulatory T cell during human Chagas' disease. Methodology/Principal ...

Tópico(s): T-cell and Retrovirus Studies

2012 - Public Library of Science | PLoS neglected tropical diseases

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Kléber Juvenal Silva Farias, Paula Renata Lima Machado, Benedito Antônio Lopes da Fonseca,

Dengue viruses are the most important arthropod‐borne viruses in terms of morbidity and mortality in the world. Since there is no dengue vaccine available for human use, we have set out to investigate the use of chloroquine as an antiviral drug against dengue. Chloroquine, an amine acidotropic drug known to affect intracellular exocytic pathways by increasing endosomal pH, was used in the in vitro treatment of Vero and C6/36 cells infected with dengue virus type 2 (DENV‐2). Real‐time RT‐PCR and plaque ...

Tópico(s): Viral Infections and Vectors

2013 - Hindawi Publishing Corporation | The Scientific World JOURNAL

Artigo Brasil Produção Nacional Revisado por pares

Cristina Melo Rocha, Renata de Mello Perez, Adalgisa P. Ferreira, Roberto José de Carvalho‐Filho, Fábio Pace, Ivonete S. Silva, José Osmar Medina Pestana, Valéria Pereira Lanzoni, Antônio Eduardo Benedito Silva, Maria Lúcia Gomes Ferraz,

Patients with end-stage renal disease (ESRD) show a high prevalence of hepatitis C, with a negative impact on the survival on hemodialysis and after renal transplantation. We evaluated the efficacy and tolerance of interferon-alpha (IFN-alpha) in HCV-infected ESRD patients on dialysis.Forty-six HCV-RNA-positive ESRD patients were studied. IFN-alpha regimen consisted of 3 million units three times a week for 12 months, and the patients were followed up for 6 months. End-of-treatment, and sustained ...

Tópico(s): Liver Disease Diagnosis and Treatment

2006 - Wiley | Liver International

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Raul Carlos Wahle, Renata Mello Perez, Patrícia Fucuta Pereira, Elze Maria Gomes Oliveira, Christini Takemi Emori, Silvia Naomi de Oliveira Uehara, Ivonete Sandra de Souza Silva, Antônio Eduardo Benedito Silva, Maria Lúcia Gomes Ferraz,

In coinfected HBV/HCV patients, HBV replication is usually suppressed by HCV over the time. No study to date has evaluated the HBV viremia in long-term follow-up after HCV treatment in hemodialysis patients with HBV/HCV coinfection. This study aimed to assess the evolution of HBV viremia after HCV treatment in this special population. Ten hemodialysis patients with HBV/HCV coinfection with dominant HCV infection (HBV lower than 2000 IU/mL) and significant fibrosis were treated with interferon-alpha ...

Tópico(s): Liver Disease Diagnosis and Treatment

2015 - Elsevier BV | The Brazilian Journal of Infectious Diseases

Artigo Brasil Produção Nacional Revisado por pares

Ivani Bisordi, Silvana Levis, Adriana Yurika Maeda, Akemi Suzuki, Teresa Keico Nagasse-Sugahara, Renato Pereira de Souza, Luiz Eloy Pereira, Jorge B. García, Matheus de P. Cerroni, Franko de A. e Silva, Cecília L. S. Santos, Benedito Antônio Lopes da Fonseca,

Arenavirus Sabiá was originally isolated from a fatal human infection in Brazil, and after the occurrence of the second fatal human case in São Paulo state, epidemiologic and virologic studies were performed in the area where the patient lived, aiming at the identification of the Sabiá natural rodent reservoir. A broadly cross-reactive enzyme-linked immunosorbent assay (ELISA) was used to screen for antibody-positive samples. Antibodies to arenavirus were detected in two of the 55 samples of Calomys ...

Tópico(s): Viral gastroenteritis research and epidemiology

2015 - Mary Ann Liebert, Inc. | Vector-Borne and Zoonotic Diseases