A. G. Morison, Jon Ashworth, Charles Hall, Nick Nuttall Environment Correspondent, Gillian Bowditch Scotland Correspondent, Alexandra Frean, Emma Wilkins and Barry Pickthall, Patricia Davies, Simon Barnes, Richard Ford, Home Correspondent, Adam Zamoyski, Bill Frost, Richard Thomson, M. J. Mitchell, Janet Bush, Economics Correspondent, Harvey Elliott, David Rhys Jones, Ivo Tennant, Barbara Bell, James Landale, Political Reporter, Philip Howard, Hilary Finch, Ian Murray, Warwick Lightfoot, Alexandra Frean Media Correspondent, Benno and Margaret Pollak, Jeff Davies, Carl Mortished, Dessa Trevisan, Nick Nuttall, Environment Correspondent, Simon Wilde, Tim Sweeney, Geoff Brown, Robert Sheehan, Bridge Correspondent, Joe Joseph, Giles Coren, Robert Miller, J. Sykes, Martin Fletcher, Roger Maynard and Adam Sage, Tom Rhodes and Sam Kiley, John Redwood, Jim Marshall, Debra Craine, Christopher Leaver, Raymond Keene Chess Correspondent, Anne Longfield, Thomas De Waal, Dalya Alberge Arts Correspondent, Peter Ackroyd, Peter Waymark, Michael Evans, Defence Correspondent, Robin Young, Mike Rosewell Rowing Correspondent, Eamonn Butler, Robert Bruce, Michael Clark, John Young, Anatole Kaletsky, Joan Baldock, R. T. Porter, David Hands, Ian McIntyre, Peter Barnard, Nicholas Wood and Janet Bush, John Bailey, Margot Norman, Rachel Bridge, James Mauro, Lucy Berrington, Lin Jenkins, Arthur Leathley, Political Correspondent, Gillian Bowditch, Scotland Correspondent, Ariana Grimes, Clive Fisher, Harvey Elliott Travel Correspondent, Janet Bush and Richard Thomson, Brian Martin, David Powell Athletics Correspondent, Raymond Keene, Jonathan Prynn, Adam Sage, Christine Buckley, Jonathan Prynn Transport Correspondent, Peter Goldsmith, Elizabeth Creak, Alix Ramsay, P. H. S, Nigel Hawkes, Barry Pickthall, Kate Alderson, Julian Muscat, Christopher Thomas, William Rees-Mogg, Joanna Pitman, David Churchill, Giles Whittell, Michael Kallenbach, Christopher Kent, Mel Webb, Peter Dolphin, Kathryn Knight, Anjana Ahuja, Norman Goodacre, Ben MacIntyre, Tony Dawe, Richard Beeston, Ben Macintyre, Graham Searjeant, David Walker, Martin Waller, Edward Grayson, Dr Thomas Stuttaford, Marianne Curphey, R. Isaacson, Yasunari Matsuura, David Powell, Margaret Fieldhouse, John Phillips, Colin Campbell, A. H. P. Humphrey, D. L. Heaton, Walter Ellis, Richard Ford,
Play the ?50,000 Game Interest rate rise sought by the Bank Clarke faces dilemma on inflation Steffi Graf's father held in tax inquiry Index Mr Norris ...
1995 - Gale Group | TDA
... 293–300.https://doi.org/10.1080/096031096334321Christopher Adam, Benno Ndulu, Nii Kwaku Sowa Liberalisation and Seigniorage revenue ...
Tópico(s): Energy Efficiency and Management
1974 - University of Chicago Press | Journal of Political Economy
Giles Smith, Andrew Robson, Janice Turner, Phil Yates, Christina Hardyment, Alexi Mostrous, Nicholas D. Hart, Robert Cole, Barry Forshaw, Rupert Mellor, Leo Lewis Asia Business Correspondent, Caroline Stacey, Christopher Whalen, David Aaronovitch, Amanda Ursell, Simon Barnes, Robin Pagnamenta Energy and Environment Editor, Laura Whateley, Peter Lansley, Barbara Pike, Simon Hills, Claire McDonald, Mark Souster, James MacMillan, Catherine Boyle, John Mulvey, Jane Knight, Sarah Urwin Jones, Michael Evans Defence Editor, Mike Harvey, Philip Howard, Carol Midgley, Ian King, John Freeman, Christine Seib, Daphne Paul, David Chater, Kate Wighton, James Bone, James Ducker, Andy Hayman, Melissa Katsoulis, James Alexander-Sinclair, Clive Davis, Rachel Campbell-Johnston, David Bull Executive Director, David Jeffs, Patrick Kidd, Jane Taylor-Hayhurst, Graham Stewart, Lauren Thompson, Joe Warwick, James Hider, Emma Griffin, John Bungey, Kevin Eason, Chris Sullivan, Andrew Norfolk, Giles Coren, Robin Pagnamenta, Rosie Millard, Vivienne Parry, Caroline Hendrie, Dr Copperfield, Ben Webster Transport Correspondent, Nancy Durrant, Vinny Lee, Valerie Elliott, Rachel Sylvester, Le Touessrok, Peter Jones, Roger Brown, Dominic Walsh, Andrew Douglas-Home Chairman, Dan Sabbagh Media Editor, Debra Craine, Rory Watson, Jane MacQuittty's, Joe Swift, John Sutherland, Tom Charity, Allan Simmons, Peter Stiff, Tim Reid, Daniel Finkelstein, Jeanette Winterson, Laura Lovett, Tom Gatti, Peter Millar, Nicholas Roe, C. Engel, Rhys Blakely, Richard Lloyd Parry, David Hands, Charles Bremner, Guillem Balague, Lucy Sweeney, Tim Teeman, David Charter, Derwent May, Kate Muir, Irene Glausiusz, Aggie MacKenzie, Russell Kempson, Ed Potton, Suzy Jagger, Trevor Johnston, Stephen Anderton, Sarah Vine, Mark Atherton, Lisa Armstrong, John Westerby, Jane Wheatley, Ron Goldstein, Tom Baldwin, Douglas Rankine, Sally Baker, Rose Garnett, Pete Paphides, Chemmy Alcott, Rob Wright, John Shepherd, Christina Koning, Edward Gorman Motor Racing Correspondent, Neil Harman Tennis Correspondent, Raymond Keene, Adam Sage, Sean O'Neill Crime and Security Editor, Suzi Godson, Lewis Smith, Kate Saunders, Rupert Penry-Jones, Matt Hughes, Bruce Dessau, Gordon Ramsay, Christine Buckley Industrial Editor, Sean O'Neill, Dr Maggie Atkinson President, Kaveh Solhekol, John Moore, Roger Phillips, Jeremy Page, Rick Jones, Chris Campling, Alice Thomson, Adam Fresco Crime Correspondent, Patrick Hosking, Richard Owen, Damian Whitworth, Rebecca O'connor, Ross Leckie, Erica Wagner, James Charles, Tom Whipple, Nick Hasell, Catriona Bass, Carlton Books, Margaret Reynolds, Robin Renwick, Kevin Maher, David Hands Rugby Correspondent, Richard Hobson Deputy Cricket Corresondent, Paul Simons, Mike Mulvihill, Nicholas Clee, Ann Brady, Steve Jelbert, Nigel Kendall, Nick Szczepanik, Joanna Pitman, Dominic Kennedy, Philip Webster Political Editor, Richard Ehrlich, Ian King Deputy Business Editor, Robert Crampton, Craig Lord, Kevin Eason Sports News Correspondent, Harriet Addison, Dominic Maxwell, Dr Andrew Tustian, Prue White, Matthew Parris, Mark Bridge, Helen Power, George Caulkin, Alan Franks, Tim Wapshott, Russell Jenkins, Caitlin Moran, Lesley Thomas, Neil Fisher, John Pincham, Iain Finlayson, Peter Riddell, Jeremy Page South Asia Correspondent, Joe Clay, John Naish, Mark Henderson, Martin Waller, Chris Ayres, Sir William Fox, Valentine Low, Patrick Foster, Sarah Butler, Ashling O'Connor, Anna Shepard, Benedict Nightingale, Anne Richardson, Louise Cohen, Rick Broadbent Athletics Correspondent, Stephen Dalton, Alyson Rudd, Frances Gibb, Tom Chesshyre, Tony Halpin, Chris Moore, Richard Morrison, David Budworth, Adam Sherwin, Valerie Grove, Simon Crompton, James Christopher, Alan Lee Racing Correspondent, Alan Price-Talbot, Alan Jackson, Owen Slot, Stephen Foster, Matt Roberts, Kim Newman, Mike Atherton Chief Cricket Correspondent, Alex Hardy, Miles Costello, Jan Raath, Sir Andrew Likierman, David Robertson, Richard Ford, Joan Smith, Mary Hodgson, Tom Devlin,
... North Face Director: Philipp Stölzl, 12A, 121min Stars: Benno Fürmann, Florian Lukas, Ulrich Tukur On selected release, ...
2008 - Gale Group | TDA
Benno Brummer, Adam Bertl, Ingo Potrykus, Hubert Felle, Roger W. Parish°,
Auxin Coleoptile Cytosolic pH Fusicoccin Growth Membrane potential Zea mays
Tópico(s): Enzyme-mediated dye degradation
1985 - Wiley | FEBS Letters
Andrew Robson, Phil Yates, Jon Ashworth, Raymond Snoddy Media Editor, Matthew Bannister, Alun Morris, David Spooner, Robert Cole, James Moore, Simon Barnes, Peter Lansley, Anne Woodham, Claire McDonald, Mark Souster, John Allen, Adrian Ham, Director-General, Ian Winrow, Jane Bolton, Philip Howard, Ian Cobain, Hilary Finch, David Chater, Bronwen Maddox Foreign Editor, Carl Mortishead and Mike Leldig, Heather Neill, Geoff Brown, Joe Joseph, John O'Leary Education Editor, Ben Webster Transport Correspondent, David McVay, Philip Webster and Tom Baldwin, Robert C. Mulholland, Thrasy Petropoulos, Stewart Tendler Crime Correspondent, Jack Malvern, Dominic Walsh, R. L. Black, Debra Craine, Jim McCue, Andrew R. Ledingham, Leon Marks, Tim Reid, Daniel Finkelstein, Ruth Gledhill Religion Correspondent, Adeline Iziren, R. Turner, Robin Young, Alan Hamilton, Oliver Wright, Nick Wyke, Greg Hurst and David Charter, Anselm Kuhn, Roland Watson, Zahid Hussain and Michael Evans Defence Editor, Charles Bremner, Helen Rumbelow, Rachel Campbell Johnston, David Charter, Clive Mathieson Telecoms Correspondent, Caroline Merrell Banking Correspondent, Angela Jameson, Russell Kempson, Richard Cork, Iain K. Stiven, Oliver Kay, M. Hammerton, Jon Mays, Matt Dickinson Football Correspondent, Ann Treneman, Geoffrey Dean, Rob Wright, Roland Watson and Christopher Walker, James Doran and Clive Mathieson, Raymond Keene, Matthew Pryor, John Russell Taylor, John Grigg, Kenneth Tynan, Edward de Bono, Oliver Holt, Richard Owen, Erica Wagner, Emily Davies, Oliver August, Nick Hasell, David Hands Rugby Correspondent, Adam Fresco, Nick Szczepanik, Douglas Izzard, Caroline Merrell and James Moore, Dearbáil Jordan, Mary Ann Sieghart, James Doran, Brian Trump, Simon de Bruxelles and Roger Boyes, Melissa Kite Political Correspondent, Christopher Walker, Kevin McCarra, Matthew Parris, Chris McGrath, Mark Court Health Industries Correspondent, Peter Riddell, Lea Paterson Economics Editor, Catherine O'Brien, Ben Webster, Stephen Sharp, Simon Jenkins, Lea Paterson, Catherine Philp, Melinda Letts, Martin Waller, Chris Ayres, James Jackson, Alan Coren, Laura Peek, Benedict Nightingale, Stephen Dalton, Peter Smith, Russell Celyn Jones, Alice Miles, Adam Sage and Daniel McGrory, Anne Ashworth, Allan Hall, Alan Lee Racing Correspondent, Sally Patten, Jan Raath, Edward Gorman Sailing Correspondent, Richard Beeston and Charles Bremner, Pamela Townsend, Sally Patten Retail Correspondent, Patience Wheatcroft, Christopher Irvine,
... Personal Column Anniversaries Forthcoming marriages Latest wills Marriages Benno Pollak Inner-city GP who did pioneering work ...
2001 - Gale Group | TDA
Hubert Felle, Benno Brummer, Adam Bertl, Roger W. Parish,
Microelectrodes were used to measure simultaneously the effects of indole-3-acetic acid (IAA) on membrane potential and cytosolic pH of corn coleoptile cells. IAA caused an initial depolarization followed by hyperpolarization, the latter displaying rhythmic oscillations. The extent of the changes in membrane potential was dependent on IAA concentration, and hyperpolarization, but not depolarization, could be detected with concentrations of IAA as low as 10 nM. Membrane hyperpolarization was preceded ...
Tópico(s): Light effects on plants
1986 - National Academy of Sciences | Proceedings of the National Academy of Sciences
C. S. LOCH., DAWSON BURNS., CECIL WALSH, , J. E. C. WELLDON., JOHN G. TALBOT., (FROM OUR CORRESPONDENT.)., ADAM BLOCK., JOHN WILLIAMS BENN., EGIDIO VITALI., CHARLES GOUGH., ROBERT ANDERSON., S. H. BUTCHER., OBSERVER., Our Tangier Correspondent.,
... The Lords And The Licensing Bill.. Reviews: Mr. Benno Schonberger., The Grimson Quartet., Salle Erard., The Strings ...
1908 - Gale Group | TDA
Vera Großmann, Martina Höckner, Houda Karmous‐Benailly, Desheng Liang, Rudolf Puttinger, Roberto Quadrelli, Benno Röthlisberger, Adam M. Huber, Lingqian Wu, Ana Spreiz, Christine Fauth, Martin Erdel, Johannes Zschocke, Gerd Utermann, Dieter Kotzot,
Grossmann V, Höckner M, Karmous‐Benailly H, Liang D, Puttinger R, Quadrelli R, Röthlisberger B, Huber A, Wu L, Spreiz A, Fauth C, Erdel M, Zschocke J, Utermann G, Kotzot D. Parental origin of apparently balanced de novo complex chromosomal rearrangements investigated by microdissection, whole genome amplification, and microsatellite‐mediated haplotype analysis. Complex chromosomal rearrangements (CCRs) are rare findings in clinical cytogenetics. As a result of the high risk of unbalanced segregation, ...
Tópico(s): Prenatal Screening and Diagnostics
2010 - Wiley | Clinical Genetics
Giles Smith, Richard Mabey, Andrew Robson, Janice Turner, Mark Winspear, Caroline Tilson, Jon Ashworth, Alexandra Frean and Bob Graham, David Adams, John Smith, Haydn Davies, Robert Cole, Matthew Syed, Bel Mooney, Rupert Mellor, mike tyson, Isabel Allende, CAH, David Sloan, Greg Hurst Political Correspondent, Jane MacQuitty, Simon Barnes, Tim De Lisle, Peter Lansley, Jill Hartley, Robert Thicknesse, Paul Hoggart, Ian Blackshaw, Ivo Tennant, Chris Rogers, Cath Urquhart Trvel Editor, Peter Cadogan, David Bickford, Dr Toby Murcott, Philip Howard, Hannah Betts, Carol Midgley, Camilla Cavendish, Dan Frank, John Freeman, David Chater, Zoe Strimpel, James Harkin, James Bone, James Ducker, Rachel Campbell-Johnston, Nic Hopkins, Hannah McGill, Clive Davis, Richard Hobson One-Day Cricket Correspondent, Kate Reardon, Chris Bowers, São paulo, Declan Buckley, Ginny Dougary, Wendy Ide, John Bungey, Kevin Eason, Geoff Brown, Bronwen Maddox Foreign Editors, Clare Stewart, Giles Coren, Richard Hudson, Grànne Gilmore, Dr Copperfield, Joe Williams and Joel Pannick, Antonia Senior, Pat Gibson, David McVay, Nancy Durrant, AC, John Clarke, Valerie Elliott, David Goldberg, James Doran Wall Street Correspondent, Debra Craine, Shirley English, Mark and Magnus, Gerard Jones, Gary Jacob, Mike Pattenden, Graham Duffill, Victoria Segal, Allan Simmons, Norman Harris, Joe Morgan, Victoria Brown, Dr Jane Collins, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Dan Sabbagh, Jane Clarke, Robert Cole Deputy Business Editor, Richard Ford Home Correspondent, Candida Crewe, Nick Robinson, Alan Hamilton, Jack Malvern Arts Reproter, Lucy S. Ripon, Michael Prowse, Rhys Blakely, Roland Watson, John Sandalls, Richard Lloyd Parry, Tom Reid, David Hands, Frayn Yeoman, Tina Gaudoin, Graham Keeley, Scott von Doviak, Ron Lewis, Heather McGregor, Matt Dickinson Chief Football Correspondent, Brian Carlo, Greg Hurst, Genevieve Fox, Tim Teeman, Derwent May, Arwa Haider, Angela Jameson, Kate Muir, Sarah Thompstone, Tom Baldwin and Jon Ashworth, Tom Petherick, Peter Paphides, David Rowan, Dan Silver, Ed Potton, Jerome Burne, Gary Duncan Economics Editor, Oliver Kay, Mr. R. L. Oxfordshire, Amber Cowan, PC, Ben MaCintyre, Sarah Vine, Mark Atherton, Simon de Bruxelies, John Westerby, Rick Broadbent, Patrick Hosking Investment Editor, Calum Carmichael, Jo Morries, Jenny Lewis, Lisa Armstrong, Jill Sherman Whitehall Editor, Mark Henderson Science Correspondent, Chris Power, Chris Smith, Dr Feelgood, Martyn Palmer, Simon de Bruxelles, Rob Wright, Geoffrey Dean, Magnus Grimond, Knights Bachelor, Gabriel Rozenberg, Benjamin Fry, Raymond Keene, Christine Buckley, Hayley McMullan, Matthew Pryor, John Attwood, Richard Brass, Rebecca O'Connor, Frizzell County, Kaveh Solhekol, Jeremy Page, Neville Scott, Andrew G. Marshall, Rick Jones, Fran Yeoman, Richard Owen, Gránne Gilmore, Mark Irving, Rebecca O'connor, Sean O'Neil, Roger Boyes, Peter Dixon, Gerdard Baker US Editor, David Hands Rugby Correspondent, Ruth Scurr, John Connolly, Paul Simons, Victoria O'brien, Adam Fresco, Nick Szczepanik, John Goodbody, Nell Harman Tennis Correspondent, Andy Williams, JD, Robert Crampton, Ian Johns, Mel Webb, Philip Webster and Charles Bremner, Julie Burchill, Dame Judith Olivia Dench, Philip Roe, Matthew Parris, Keith Thomas, Simon Taylor, Amanda Craig, Ian Davis, Philp Howard, Russell Jenkins, Ingrid Mansell, Nick Hasell Stok Markets, Alan Lee, Jonathan Rendall, Tony Hannan, Celia Dodd, Rajeav Syal, Sheila Keating, Caitlin Moran, Ben Watts, Edward owen and Daniel McGrory, Elizabeth Noyes, Alison Gibson, Anne Ashworth Personal Finance Editor, Kieran Falconer, Lewis Stuart, Martin Waller, Mark Henderson, James Jackson, Carl Mortished International Business Editor, Ashling O'Connor, Darian Leader, Angus Batey, Mark MacKinzie, Jill Crawshaw, Stephen Dalton, Ben Hoyle, Valerie Lucas, Bill Edgar, Alyson Rudd, Tom Chesshyre, Paul Connolly, James Christopher, Rebecca Magill, Colin Dauris, Simon Crompton, R. M. Lamming, Alexandra Blair Education Correspondent, Alan Jackson, Owen Slot, Anne Celine Jaeger, Robbie Millen, Will Hide, Jenny Davey, Simon Worral and Jayne Dowle, Christopher Foster, Andrew Dow, Peter Klinger, Patience Wheatcroft, Hannahd Betts, Anthony Browne and Rory Watson, Christopher Irvine, George Guise, Irma Kurtz, Tom Chesshrye,
... to Neverland in a beautiful … Sky Movies Entertainment Benno furmann and Heath Ledger are out to save ...
2005 - Gale Group | TDA
Benno Pokorny, Michelle Adams,
The diversity of C&I sets is often a cause for uncertainty and confusion, and probably one of the reasons for the still unsatisfactory acceptance of C&I as a support for implementation of sustainable forest management so far. In order to halt this erosion of confidence in C&I the presented paper evaluated the diversity of five C&I sets (CIFOR, ACM, FSC, ITTO and Tarapoto) relevant for the Brazilian Amazon by analyzing frequencies of C&I in relation to parameters about content and quality. The study ...
Tópico(s): Forest Management and Policy
2003 - Commonwealth Forestry Association | The International Forestry Review
Benno Schnyder, Jacqueline Adam, Andri Rauch, Maria Christine Thurnheer, Werner J. Pichler,
Abacavir hypersensitivity (AH) is a potentially severe drug reaction that frequently involves the skin, the liver, and the lung. It is peculiar because of the following features: (a) It is strongly associated with HLA-B*57:01; 47% of HLA-B*57:1 carriers develop AH on exposure. Thus, HLA-B*57:01 has become an established marker for the identification of patients at risk of AH.1Mallal S. Phillips E. Carosi G. Molina J.M. Workman C. Tomazic J. et al.PREDICT-1 Study TeamHLA-B*5701 screening for hypersensitivity ...
Tópico(s): Asthma and respiratory diseases
2013 - Elsevier BV | Journal of Allergy and Clinical Immunology
Ebru Baykara, Benno Gesierich, Ruth Adam, Anil M. Tuladhar, J. Matthijs Biesbroek, Huiberdina L. Koek, Stefan Ropele, Éric Jouvent, Hugues Chabriat, Birgit Ertl‐Wagner, Michael Ewers, Reinhold Schmidt, Frank–Erik de Leeuw, Geert Jan Biessels, Martin Dichgans, Marco Duering,
Objective To establish a fully automated, robust imaging marker for cerebral small vessel disease (SVD) and related cognitive impairment that is easy to implement, reflects disease burden, and is strongly associated with processing speed, the predominantly affected cognitive domain in SVD. Methods We developed a novel magnetic resonance imaging marker based on diffusion tensor imaging, skeletonization of white matter tracts, and histogram analysis. The marker (peak width of skeletonized mean diffusivity [ ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2016 - Wiley | Annals of Neurology
Charles Adams, Benno Ferrarini, Donghyun Park,
The central objective of this paper is to empirically examine the issue of fiscal sustainability in developing Asia. To do so, we first diagnose the region's public finances by analyzing the evolution of key fiscal indicators over time and across subregions. We then estimate fiscal policy response functions that measure the adjustment of the primary fiscal balance to public debt positions. Overall, our results indicate that the region's public finances are in good shape as a result of responsible ...
Tópico(s): Local Government Finance and Decentralization
2010 - RELX Group (Netherlands) | SSRN Electronic Journal
Joern Groene, Ulrich Mansmann, Reinhard Meister, Eike Staub, Stefan Roepcke, Maya Heinze, Irina Klaman, Thomas Brümmendorf, K. Hermann, Christoph Loddenkemper, Christian Pilarsky, Benno Mann, Hans‐Peter Adams, H. J. Buhr, André Rosenthal,
Abstract UICC stage II and III colorectal cancers (CRC) differ fundamentally in prognosis and therapeutic concepts. To analyze differential gene expression between both stages and to establish a relationship between molecular background and clinical presentation, tumor material from 36 unselected consecutive patients presenting with sporadic CRC, 18 UICC stage II and 18 UICC stage III, were laser microdissected to separate epithelial tumor cells. Gene expression levels were measured using U133A Affymetrix ...
Tópico(s): Colorectal Cancer Screening and Detection
2006 - Wiley | International Journal of Cancer
Susanne Hipp, Petra Deegen, Joachim Wahl, Diann Blanset, Oliver S. Thomas, Benno Rattel, Paul J. Adam, Matthias Friedrich,
Abstract BI 836909 is a Bispecific T cell Engager (BiTE®), designed to redirect the body's endogenous T cells towards cells expressing B cell maturation antigen (BCMA) on the cell surface. BCMA is a highly plasma cell specific antigen and shows homogeneous expression on the cell surface of multiple myeloma, plasma cell leukemia and plasmacytoma cells. In normal tissues, BCMA expression is restricted to plasma cells, while other normal tissues do not express BCMA. This highly selective expression pattern ...
Tópico(s): Immunotherapy and Immune Responses
2015 - Elsevier BV | Blood
Susanne Hipp, YT Tai, Diann Blanset, P Deegen, Jochen Wahl, Oliver S. Thomas, Benno Rattel, Paul J. Adam, K C Anderson, Matthias Friedrich,
B-cell maturation antigen (BCMA) is a highly plasma cell-selective protein that is expressed on malignant plasma cells of multiple myeloma (MM) patients and therefore is an ideal target for T-cell redirecting therapies. We developed a bispecific T-cell engager (BiTE) targeting BCMA and CD3ɛ (BI 836909) and studied its therapeutic impacts on MM. BI 836909 induced selective lysis of BCMA-positive MM cells, activation of T cells, release of cytokines and T-cell proliferation; whereas BCMA-negative cells ...
Tópico(s): Immunotherapy and Immune Responses
2016 - Springer Nature | Leukemia
Susanne Hipp, Y-T Tai, Diann Blanset, P Deegen, Jochen Wahl, Oliver S. Thomas, Benno Rattel, Paul J. Adam, K C Anderson, Matthias G. Friedrich,
Correction to: Leukemia advance online publication 13 January 2017; doi:10.1038/leu.2016.388 Following the publication of this article, it was noted that the HTML version contained the wrong AAP date. The correct AAP date is 27 December 2016.
Tópico(s): Multiple Myeloma Research and Treatments
2017 - Springer Nature | Leukemia
Christopher Adam, Benno J. Ndulu, Nii Kwaku Sowa,
This article examines the implications for seigniorage revenue of exchange rate and asset market liberalisation. It is argued that liberalisation lowers the average and marginal seigniorage capacity of governments by increasing the elasticity of substitution between base money and other financial assets. Moreover, to the extent that exchange rate liberalisation eliminates goods market rationing, it simultaneously reduces the return to holding precautionary and speculative money balances. The implication ...
Tópico(s): Fiscal Policies and Political Economy
1996 - Taylor & Francis | The Journal of Development Studies
Barry Demchak, David Otasek, Alexander R. Pico, Gary D. Bader, Keiichiro Ono, Brett Settle, Eric Sage, John H. Morris, William J.R. Longabaugh, Christian Lopes, Michael Kucera, Adam Treister, Benno Schwikowski, Piet Molenaar, Trey Ideker,
Cytoscape is the premiere platform for interactive analysis, integration and visualization of network data. While Cytoscape itself delivers much basic functionality, it relies on community-written apps to deliver specialized functions and analyses. To date, Cytoscape's CyREST feature has allowed researchers to write workflows that call basic Cytoscape functions, but provides no access to its high value app-based functions. With Cytoscape Automation, workflows can now call apps that have been upgraded ...
Tópico(s): Gene expression and cancer classification
2018 - Faculty of 1000 | F1000Research
I F DUFF, John R. Gamble, P W WILLIS, P. Hodgson, W S WILSON, J A POLHEMUS,
... Thrombosis and embolism. I. International Conference, Basel, 1954, Benno Schwabe & Co., Basel, p. 31. Google Scholar11. Adams WR: Treatment of cardiovascular diseases with anticoagulants, Postgrad. ...
Tópico(s): Atrial Fibrillation Management and Outcomes
1955 - American College of Physicians | Annals of Internal Medicine
Peter Cornillon, Jennifer Adams, M. Benno Blumenthal, Eric P. Chassignet, Ethan Davis, Steve C. Hankin, James L. Kinter, Roy Mendelssohn, James T. Potemra, Ashwanth Srinivasan, J. Sirott,
2009 - Oceanography Society | Oceanography
Marco Duering, M. Konieczny, Steffen Tiedt, Ebru Baykara, Anil M. Tuladhar, Esther van Leijsen, Philippe Lyrer, Stefan T. Engelter, Benno Gesierich, Melanie Achmüller, Christian Barro, Ruth Adam, Michael Ewers, Martin Dichgans, Jens Kühle, Frank–Erik de Leeuw, Nils Peters,
Neurofilament light chain (NfL) is a blood marker for neuroaxonal damage. We assessed the association between serum NfL and cerebral small vessel disease (SVD), which is highly prevalent in elderly individuals and a major cause of stroke and vascular cognitive impairment.Using a cross-sectional design, we studied 53 and 439 patients with genetically defined SVD (Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy [CADASIL]) and sporadic SVD, respectively, as well ...
Tópico(s): Amyotrophic Lateral Sclerosis Research
2018 - | Journal of Stroke
Heike Martini, Martin Weidenbörner, Susanne Adams, Benno Kunz,
3- and 7-hydroxyflavone and their acetic acid esters were tested against Cladosporium herbarum and Penicillium glabrum for antifungal activity. The effect of the hydroxylated flavones was relatively low whereas the ester derivatives were substantially more active.
Tópico(s): Natural product bioactivities and synthesis
1997 - Cambridge University Press | Mycological Research
James Sackerman, Jennifer J. Donegan, Colin S. Cunningham, Ngoc Nhung Nguyen, Kelly Lawless, Adam Long, Robert H. Benno, Georgianna G. Gould,
Zebrafish (Danio rerio) associative responses are useful for pharmaceutical and toxicology screening, behavioral genetics, and discovering neural mechanisms involved in behavioral modulation. In novel environments, zebrafish swim to tank bottoms and dark backgrounds, behaviors attributed to anxiety associated with threat of predation. To examine possible genetic effects of inbreeding and segregation on this behavior, we compared Zebrafish International Resource Center (ZIRC) AB and WIK lines to zebrafish ...
Tópico(s): Zebrafish Biomedical Research Applications
2010 - eScholarship Publishing, University of California | International Journal of Comparative Psychology
Jacqueline Adam, Klara Eriksson, Benno Schnyder, Stefano Fontana, Werner J. Pichler, Daniel Yerly,
The antiretroviral drug abacavir (abc) elicits severe drug hypersensitivity reactions in HLA ‐ B *5701 + individuals. To understand the abc‐specific activation of CD 8 + T cells, we generated abc‐specific T ‐cell clones (abc‐ TCC s). Abc reactivity could not be linked to the metabolism and/or processing of the drug, since abc metabolizing enzymes were not expressed in immune cells and inhibition of the proteasome in APC s did not affect TCC reactivity. Ca 2+ influx assays revealed different reactivity patterns ...
Tópico(s): Immune Cell Function and Interaction
2012 - Wiley | European Journal of Immunology
Thomas Höhler, Esther Reuss, Petra Adams, Brigitte Bartsch, Benno Weigmann, Markus Wörns, Peter R. Galle, Anja Victor, Markus F. Neurath,
Th1 and Th2 cytokines secreted by polarized effector T cells play a pivotal role in the development of autoimmune and allergic diseases. However, the genetic basis of cytokine production by T lymphocytes in humans is poorly understood. In this study, we investigated the genetic contribution to cytokine production and regulation of T cell-specific transcription factors in a prospective twin study. We found a substantial genetic contribution to the production of Th1 cytokines such as IFN-gamma and ...
Tópico(s): Immune Cell Function and Interaction
2005 - American Association of Immunologists | The Journal of Immunology
Benno Böckl, André Wedel, Adam Misik, Klaus Drechsler,
Automated Fiber Placement (AFP) is a widely used production process for the manufacturing of large scale CFRP parts. However, the occurrence of manufacturing defects such as gaps or overlaps is still a common problem in today’s AFP production environments. This study investigates the effect of different defect configurations on the mechanical performance (i.e., tensile strength, flexural strength, and shear strength) of AFP laminates. The results are then linked to the data generated “inline” by a ...
Tópico(s): Surface Roughness and Optical Measurements
2022 - SAGE Publishing | Journal of Reinforced Plastics and Composites
Benno Brinkhaus, Stephanie Roll, Susanne Jena, Katja Icke, Daniela Adam, Sylvia Binting, Fabian Lotz, Stefan N. Willich, Claudia M. Witt,
Although the available evidence is insufficient, acupuncture is used in patients suffering from chronic asthma. The aim of this pragmatic study was to investigate the effectiveness of acupuncture in addition to routine care in patients with allergic asthma compared to treatment with routine care alone.Patients with allergic asthma were included in a randomized controlled trial and randomized to receive up to 15 acupuncture sessions over 3 months or to a control group receiving routine care alone. ...
Tópico(s): Psychosomatic Disorders and Their Treatments
2017 - Mary Ann Liebert, Inc. | The Journal of Alternative and Complementary Medicine
Csaba Cserép, Balázs Pósfai, Nikolett Lénárt, Rebeka Fekete, Zsófia I. László, Zsolt Lele, Barbara Orsolits, Gábor Molnár, Steffanie Heindl, Anett D. Schwarcz, Katinka Ujvári, Zsuzsanna Környei, Krisztina Tóth, Eszter Szabadits, Beáta Sperlágh, Mária Baranyi, László Csiba, Tibor Hortobágyi, Zsófia Maglóczky, Bernadett Martinecz, Gábor Szabó, Ferenc Erdélyi, R. Szipöcs, Michael M. Tamkun, Benno Gesierich, Marco Duering, István Katona, Arthur Liesz, Gábor Tamás, Ádám Dénes,
Microglia are the main immune cells in the brain and have roles in brain homeostasis and neurological diseases. Mechanisms underlying microglia-neuron communication remain elusive. Here, we identified an interaction site between neuronal cell bodies and microglial processes in mouse and human brain. Somatic microglia-neuron junctions have a specialized nanoarchitecture optimized for purinergic signaling. Activity of neuronal mitochondria was linked with microglial junction formation, which was induced ...
Tópico(s): Immune cells in cancer
2019 - American Association for the Advancement of Science | Science
Waltraud Pfeilschifter, Dana Farahmand, Daniela Niemann, Benno Ikenberg, Carina Hohmann, Mario Abruscato, Sven Thonke, Adam Strzelczyk, Günther Hedtmann, Tobias Neumann‐Haefelin, Rainer Kollmar, Oliver C. Singer, A. Ferbert, Thorsten Steiner, Helmuth Steinmetz, Anke Reihs, Björn Misselwitz, Christian Foerch,
The first specific antidote for non-vitamin K antagonist oral anticoagulants (NOAC) has recently been approved. NOAC antidotes will allow specific treatment for 2 hitherto problematic patient groups: patients with oral anticoagulant therapy (OAT)-associated intracerebral hemorrhage (ICH) and maybe also thrombolysis candidates presenting on oral anticoagulation (OAT). We aimed to estimate the frequency of these events and hence the quantitative demand of antidote doses on a stroke unit.We extracted data ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2016 - Karger Publishers | Cerebrovascular Diseases