Masahiro Kanai, Shea J. Andrews, Mattia Cordioli, Christine Stevens, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Akiko Iwasaki, Juha Karjalainen, Juha Mehtonen, Matti Pirinen, Karolina Chwiałkowska, Amy Trankiem, Mary K. Balaconis, Kumar Veerapen, Brooke N. Wolford, Hajar Fauzan Ahmad, Shea J. Andrews, Kathrin Aprile von Hohenstaufen Puoti, Cindy G. Boer, Palwendé Romuald Boua, Guillaume Butler‐Laporte, Carmen L. Cadilla, Karolina Chwiałkowska, Francesca Colombo, Venceslas Douillard, Nicole Dueker, Atanu Kumar Dutta, Yasser M. El‐Sherbiny, Madonna M. Eltoukhy, Sahar Esmaeeli, Annika Faucon, Marie-Julie Favé, Israel Fernández Cadenas, Margherita Francescatto, Laurent C. Francioli, Lude Franke, Macarena Fuentes‐Guajardo, Rocío Gallego Durán, David Gómez-Cabrero, Emi N. Harry, Philip R. Jansen, József Szentpéteri, Elżbieta Kaja, Masahiro Kanai, Chloe Kirk, Athanasios Kousathanas, José Eduardo Krieger, Sanjay Patel, Audrey Lemaçon, Sophie Limou, Píetro Lió, Eirini Marouli, M. Marttila, Carolina Medina‐Gómez, Yael Michaeli, Isabelle Migeotte, Soumyajit Mondal, Andrés Moreno‐Estrada, Leire Moya, Tomoko Nakanishi, Jamal Nasir, Dorote Pasko, Nathaniel M. Pearson, Alexandre C. Pereira, James R. Priest, Vid Prijatelj, Ivana Nedeljković, Alexander Teumer, Réka Várnai, Manuel Romero‐Gómez, Christina Roos, Jeffrey Rosenfeld, Ruolin Li, Eva C. Schulte, Claudia Schurmann, Bahareh Sedaghati-khayat, Doaa Shaheen, Ilangumaran Shivanathan, Csilla Sipeky, Zhou Sirui, Pasquale Striano, Yosuke Tanigawa, Alicia Utrilla Remesal, Nirmal Vadgama, Costanza L. Vallerga, Sander W. van der Laan, Ricardo A. Verdugo, Qingbo Wang, Wei Zhou, Ummu Afeera Zainulabid, Ruth N. Zárate, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Catherine H. Weldon, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Alexander S. Hatoum, Amit Agrawal, Ryan Bogdan, Sarah M. C. Colbert, Wesley K. Thompson, Chun Fan, Emma C. Johnson, Lyudmila Niazyan, Mher Davidyants, Arsen Arakelyan, Diana Avetyan, Makhabbat Bekbossynova, Ainur Tauekelova, Mukhtar Tuleutayev, Aliya Sailybayeva, Yerlan Ramankulov, Elena Zholdybayeva, Jarkyn Dzharmukhanov, Kuat Kassymbek, Tatyana Tsechoeva, Gulsimzhan Turebayeva, Zauresh Smagulova, Timur Muratov, Sadyk Khamitov, Alex S. F. Kwong, Nicholas J. Timpson, Mari Niemi, Souad Rahmouni, Julien Guntz, Y Beguin, Mattia Cordioli, Sara Pigazzini, Lindokuhle Nkambule, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Stéphanie Gofflot, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Nicky Tiembe, David Morrison, Jonathan Afilalo, Vincent Mooser, J. Brent Richards, Simon Rousseau, Madéleine Durand, Guillaume Butler‐Laporte, Vincenzo Forgetta, Lætitia Laurent, Zaman Afrasiabi, Meriem Bouab, Chris Tselios, Xiaoqing Xue, Marc Afilalo, Maureen Oliveira, Janick St-Cyr, Ariane Boisclair, Jiannis Ragoussis, Daniel Auld, Daniel E. Kaufmann, G. Mark Lathrop, Guillaume Bourque, Simon Décary, Emilia Liana Falcone, Alexandre Montpetit, Alain Piché, Christel Renoux, Natàlia Blay, Sze Man Tse, Ma’n H. Zawati, Lea K. Davis, Nancy J. Cox, Jennifer E. Below, Julia Sealock, Annika Faucon, Megan M. Shuey, Hannah G. Polikowsky, Lauren E. Petty, Douglas M. Shaw, Hung‐Hsin Chen, Wanying Zhu, Axel Schmidt, Kerstin U. Ludwig, Carlo Maj, Selina Rolker, Daniella Balla, Pari Behzad, Markus M. Nöthen, Julia Fazaal, Verena Keitel, Verena Keitel, Björn‐Erik Ole Jensen, Torsten Feldt, Nikolaus Marx, Michael Dreher, Isabell Pink, Markus Cornberg, Thomas Illig, Clara Lehmann, Philipp Schommers, Jan Rybniker, Max Augustin, Lisa Knopp, Ingo Kurth, Thomas Eggermann, Sonja Volland, Marc Moritz Berger, Thorsten Brenner, Anke Hinney, Oliver Witzke, Margarethe Konik, Robert Bals, Christian Herr, Nicole Ludwig, Jörn Walter, Eicke Latz, Susanne V. Schmidt, Jennifer D. Brooks, Shelley B. Bull, Lloyd T. Elliott, France Gagnon, Celia M.T. Greenwood, Rayjean J. Hung, Jerry Lawless, Andrew D. Paterson, Lei Sun, Michael J. Rauh, Laurent Briollais, Anne‐Claude Gingras, Yvonne Bombard, Trevor J. Pugh, Jared T. Simpson, Lee Goneau, Anat R. Halevy, David M. Maslove, Bjug Borgundvaag, Luke Devine, Erin Bearss, David Richardson, Saranya Arnoldo, Steven Friedman, Ahmed Taher, Seth Stern, Marc Dagher, Jovanka Vasilevska‐Ristovska, Catherine M. Biggs, Beata Mickiewicz, Lisa J. Strug, Stephen W. Scherer, Naveed Aziz, Steven J.M. Jones, Bartha Maria Knoppers, Mark Lathrop, Stuart E. Turvey, Rae S. M. Yeung, Upton Allen, Angela M. Cheung, Margaret S. Herridge, Miranda Hunt, Jordan Lerner‐Ellis, Jennifer Taher, Rulan S. Parekh, Linda T. Hiraki, Juthaporn Cowan, Francine M. Ducharme, Mario Ostrowski, François P. Bernier, Jim Kellner, Elika Garg, Samantha Yoo, Caitlyn Vlasschaert, Erika Frangione, Monica Chung, Abdul Noor, Elena Greenfeld, Karen Colwill, Marc Clausen, Gary Chao, FengYun Yue, Marvin J. Fritzler, Joseph Whitney, Bhooma Thiruvahindrapuram, Jean‐Michel Garant, Rohan Abraham, Adrienne D. Davis, Aaron Campigotto,
Investigating the role of host genetic factors in COVID-19 severity and susceptibility can inform our understanding of the underlying biological mechanisms that influence adverse outcomes and drug development 1,2 .Here we present a second updated genome-wide association study (GWAS) on COVID-19 severity and infection susceptibility to SARS-CoV-2 from the COVID-19 Host Genetic Initiative (data release 7).We performed a meta-analysis of up to 219,692 cases and over 3 million controls, identifying 51 ...
Nature Portfolio
Constantine A. Gatsonis, Denise R. Aberle, Christine D. Berg, William C. Black, Timothy R. Church, Richard M. Fagerstrom, Barbara Galen, Ilana F. Gareen, Jonathan Goldin, John K. Gohagan, Bruce J. Hillman, C. Carl Jaffe, Barnett S. Kramer, David A. Lynch, Pamela M. Marcus, Mitchell D. Schnall, Daniel C. Sullivan, Dorothy Sullivan, Carl J. Zylak, Christopher H. Cagnon, Dianna D. Cody, Glenn Fletcher, Michael Flynn, Philip F. Judy, Randell Kruger, Frederick J. Larke, Michael F. McNitt‐Gray, Thomas Payne, J. Anthony Seibert, Xizeng Wu, Gerald F. Abbott, Judith K. Amorosa, R. Graham Barr, Phillip M. Boiselle, Caroline Chiles, Robert A. Clark, Lynn Coppage, Robert Falk, Elliot K. Fishman, David Gemmel, Jonathan Goldin, Eric T. Goodman, Eric Hart, Todd R. Hazelton, Elizabeth Johnson, Ella A. Kazerooni, Barbara L. McComb, Geoffrey McLennan, Reginald F. Munden, James Ravenel, Michael A. Sullivan, Stephen J. Swensen, Drew A. Torigian, Kay H. Vydareny, John A. Worrell, Peter W. Balkin, Mona N. Fouad, Matthew T. Freedman, Kavita Garg, Edward P. Gelmann, David S. Gierada, William G. Hocking, Subbarao Inampudi, Claudine Isaacs, Paul A. Kvale, Howard Mann, William Manor, Hrudaya Nath, Douglas J. Reding, David L. Spizarny, Diane C. Strollo, John Waltz, Mei‐Hsiu Chen, Fenghai Duan, Grant Izmirilian, Paul F. Pinsky, Philip C. Prorok, Anthony B. Miller, Martin J. Edelman, William K. Evans, Robert S. Fontana, Mitchell Machtay, Kenneth W. Clark, Kathy L. Clingan, Melissa Ford, Guillermo Márquez, Steven M. Moore, Peter Ohan, Thomas Payne, Steven Peace, Jennifer L. Rosenbaum, R. Graham Barr, William C. Black, Drew A. Torigian, Kay H. Vydareny, John A. Worrell, Robert C. Young, David S. Alberts, David L. DeMets, Peter Greenwald, Paula Jacobs, Theresa C. McLoud, David P. Naidich, James M. Tatum, Edward A. Sausville, Wylie Burke, Gene Colice, Brenda K. Edwards, Scott Emerson, John Fletcher, Sylvan Green, Russell Harris, Jeffrey S. Klein, Edward L. Korn, Robert Mayer, Joe V. Selby, David W. Sturges, Bruce W. Turnbull, Thomas J. Watson, Stephen Baylin, Neil E. Caporaso, Philip A. Dennis, Steve Dubinett, Wilbur A. Franklin, William E. Grizzle, Fred R. Hirsch, Pierre P. Massion, Kathy McKeeta-Frobeck, John D. Minna, Edward F. Patz, Margaret R. Spitz, Christine B. Berg, Donald K. Corle, Ping Hu, Grant Izmirlian, Jennifer Gaegler, Susan Hoffman, Charles Jackson, Erin O. Lange, Evanthia Papadopoulos, Constantine Gatsonis, Ilana F. Gareen, Charles Apgar, Anna Boyle, Tom Caldwell, Nancy Fredericks, Deborah Harbison, Donna Hartfeil, Sharon Jones, Steve King, Irene Mahon, Rosa Medina, Cindy Masiejczyk, Peter Zamora, Hank Brastater, Vish Iyer, Jincy George, Dinakar Gopalakrishnan, Patricia Blair, Michael Bradley, C. Crozier, M. Oh, Nicole Spiese, Chris Steward, Mary Kelly-Truran, Tess Thompson, Erin Cunningham, Anthony Levering, Kathleen McMurtrie, Michael Nahill, Sharlene Snowden, Kesha Smith, Fraser Wilton, Timothy T. Welsh, Rex Welsh, Wendell Christie, Stephanie Clabo, Roberta Clune, Natalie Cunningham, J. C. Upshaw Downs, Lindsey Dymond, Julianne Falcone, Shani Harris, Pam Harvey, Jane E. Hill, Laura Hill, Donna Letizia, Kendrick Looney, Hugh McGinley, Angelee Mean, Marcella Moore, Ryan J. Norton, Valentina Ortico, Sophia Sabina, R. Cabrera Sole, Jo Ann Stetz, Arnold Ssali, John Stubblefield, Tina Taylor, Shovonna White, Jiahong Lu, Amanda Adams, Sarah E. Baum, Meridith Blevins, Patricia S. Fox, Vincent Girardi, Jeremy Gorelick, EDWARD LIVINGSTON HUNT, Quentin McMullen, Karthikeyan Meganathan, Regina Rendas‐Baum, Jo Rean D Sicks, Bradley S. Snyder, Melanie Yeh, Maryann Duggan, Cheryl Souza, Jack Cahill, Brenda Brewer, Barbara O’Brien, G. Devereux, Melissa S. Fritz, Miriam Galbraith, Judith Harkins, Kristen Keating, Kirk Midkiff, Usha Singh, Thea Palmer Zimmerman, Nancy Payte, Helen Price, Clifford Caughman, Ramachandra Chanapatna, Mike Florzyk, Annabelle Lee, Alan Morgan, Jennifer Yang, L. Ellen Martinusen, June McSwain, Rhonda Rosario, Jagdish Singh, R. Adam DeBaugh, Sharan Campleman, Mary Mesnard, Lawrence R. Ragard, Terry Lewis, Lois Roberts, Vijayasri Narayanaswami, Vanessa Ralda, William C. Lake, Thomas Riley, Jonathan B. Clapp, Joe Austin, Brian K. Irons, Fang F. Xu, Gordon C. Jones, Michael A. Young, Andrew Goodman, Crissy Kibic, Patricia Sheridan, Nancy Kadish, Denise Moline, Rachel Phillips, Michele Adkinson, David Creed, Tammy DeCoste, Debbie Gembala, Sally Hurst, Elizabeth M. King, Joy Knowles, Pamela McBride, Patricia Pangburn, Judy Preston, Karen T. Stokes, Patricia Tesch, Susan Wenmoth, Linda Galocy, Deanna Mandley, Gail Orvis, Alphonso Dial, Letitia Clark, Lawrence Cohen, Joanne Gerber, Carlos Jamis‐Dow, Erini Makariou, Edward R. Smith, Amy Garrett, Colleen McGuire, Sarah Neff, Tara Riley, Sara Cantrell, Glynis Marsh, Chrispina Wray, Baigalmaa Yondonsambuu, Ulander Giles, Morgan Ford, Venus Brown, Amy Lita Evangelista,
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older current and former heavy smokers for early detection of lung cancer, which is the leading cause of cancer-related death in the United States. Five-year survival rates approach 70% with surgical resection of stage IA disease; however, more than 75% of individuals have incurable locally advanced or metastatic disease, the latter ...
Radiological Society of North America
Mari Niemi, Juha Karjalainen, Rachel G. Liao, Benjamin M. Neale, Mark J. Daly, Andrea Ganna, Gita A. Pathak, Shea J. Andrews, Masahiro Kanai, Kumar Veerapen, Israel Fernández‐Cadenas, Eva C. Schulte, Pasquale Striano, M. Marttila, Camelia C. Minică, Eirini Marouli, Mohd Anisul Karim, Frank R. Wendt, Jeanne E. Savage, Laura Sloofman, Guillaume Butler‐Laporte, Han‐Na Kim, Stavroula Kanoni, Yukinori Okada, Jinyoung Byun, Younghun Han, Mohammed Jashim Uddin, George Davey Smith, Cristen J. Willer, Joseph D. Buxbaum, Juha Mehtonen, Hilary K. Finucane, Mattia Cordioli, Alicia R. Martin, Wei Zhou, Bogdan Paşaniuc, Hanna Julienne, Hugues Aschard, Huwenbo Shi, Loïc Yengo, Renato Polimanti, Maya Ghoussaini, Jeremy Schwartzentruber, Ian Dunham, Karolina Chwiałkowska, Margherita Francescatto, Amy Trankiem, Mary K. Balaconis, Lea K. Davis, Sulggi A. Lee, James R. Priest, Alessandra Renieri, Vijay G. Sankaran, David A. van Heel, Patrick Deelen, J. Brent Richards, Tomoko Nakanishi, Les Biesecker, V. Eric Kerchberger, J. Kenneth Baillie, Francesca Mari, Anna Bernasconi, J. Kenneth Baillie, Arif Canakoglu, Brooke N. Wolford, Annika Faucon, Atanu Kumar Dutta, Claudia Schurmann, Emi N. Harry, Ewan Birney, Huy Nguyen, Jamal Nasir, Mari Kaunisto, Matthew Solomonson, Nicole Dueker, Nirmal Vadgama, Sophie Limou, Souad Rahmouni, Hamdi Mbarek, Dima Darwish, Md Mesbah Uddin, Raquel Albertos, Jordi Pèrez‐Tur, Ruolin Li, Lasse Folkersen, Ida Moltke, Nils Koelling, Alexander Teumer, Athanasios Kousathanas, Alicia Utrilla, Ricardo A. Verdugo, Ruth Zárate, Carolina Medina‐Gómez, David Gómez-Cabrero, Elena Carnero‐Montoro, Carmen L. Cadilla, Andrés Moreno‐Estrada, Adriana Garmendia, Leire Moya, Bahareh Sedaghati-khayat, Palwendé Romuald Boua, Marie-Julie Favé, Laurent C. Francioli, Audrey Lemaçon, Isabelle Migeotte, Sanjay Patel, Réka Várnai, József Szentpéteri, Csilla Sipeky, Francesca Colombo, Kathrin von Hohenstaufen, Píetro Lió, Costanza L. Vallerga, Qingbo Wang, Yosuke Tanigawa, Hogune Im, Chulho Han, Han Song, Jiwoo Lim, Y.‐A. Lee, Sugyeong Kim, Sangyoon Im, Biljana Atanasovska, Hajar Fauzan Ahmad, Cindy G. Boer, Philip R. Jansen, Lude Franke, Elżbieta Kaja, Dorota Pasko, Ingrid Kennis-Szilagyi, Sergey A. Kornilov, Vid Prijatelj, Ivana Nedeljković, Ilangkumaran Sivanadhan, Sarala Perumal, Sahar Esmaeeli, Nathaniel M. Pearson, Adam Auton, Janie F. Shelton, Anjali J. Shastri, Teresa Filshtein-Sonmez, Daniella Coker, Antony Symons, Jorge Esparza-Gordillo, Stella Aslibekyan, Jared O’Connell, Chelsea Ye, Catherine H. Weldon, Minoli A. Perera, Kevin J. O’Leary, Matthew Tuck, Travis J. O’Brien, David Meltzer, Peter H. O’Donnell, Edith A. Nutescu, Guang Yang, Cristina Alarcón, Stefanie Herrmann, Sophia Mazurek, Jeff Banagan, Zacharia Hamidi, April Barbour, Noora Raffat, Diana Moreno, Paula N. Friedman, Bart Ferwerda, Diederik van de Beek, Matthijs C. Brouwer, Alexander P. J. Vlaar, W. Joost Wiersinga, Daniëlle Posthuma, Elleke Tissink, A. H. Koos Zwinderman, Emil Uffelmann, Michiel A. van Agtmael, Anne Geke Algera, Frank van Baarle, Diane Bax, Martijn Beudel, Harm Jan Bogaard, Marije K. Bomers, Peter I. Bonta, Lieuwe D. J. Bos, Michela Botta, Justin de Brabander, Godelieve de Bree, Sanne de Bruin, Marianna Bugiani, Esther Bulle, Osoul Chouchane, Alex Cloherty, Dave A. Dongelmans, Paul Elbers, Lucas M. Fleuren, Suzanne E. Geerlings, Bart F. Geerts, Teunis B. H. Geijtenbeek, Armand R. J. Girbes, Abraham Goorhuis, Martin P. Grobusch, Florianne Hafkamp, Laura A. Hagens, Jörg Hamann, Vanessa Harris, Robert Hemke, Sabine Hermans, Leo Heunks, Markus W. Hollmann, Janneke Horn, Joppe W. Hovius, Menno D. de Jong, Rutger Koning, Niels van Mourik, Jeannine F. Nellen, Esther J. Nossent, Frederique Paulus, Edgar Peters, Tom van der Poll, Bennedikt Preckel, Jan M. Prins, Jorinde Raasveld, Tom D. Y. Reijnders, Michiel Schinkel, Marcus J. Schultz, Alex R. Schuurman, Kim Sigaloff, Marry R. Smit, Cornelis Stijnis, Willemke Stilma, Charlotte E. Teunissen, Patrick Thoral, Anissa M. Tsonas, Marc van der Valk, Denise P. Veelo, Heder de Vries, Michèle van Vugt, Dorien Wouters, René Minnaar, Adrie Kromhout, Kees W. J. van Uffelen, Ruud A. Wolterman, Genevieve Roberts, Daniel J. Park, Catherine A. Ball, Marie V. Coignet, Shannon McCurdy, Spencer C. Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Miloš Pavlović, Eurie L. Hong, Kristin A. Rand, Ahna R. Girshick, Harendra Guturu, Asher Haug Baltzell, Souad Rahmouni, Julien Guntz, Y Beguin, Sara Pigazzini, Lindokuhle Nkambule, Youssef Bouysran, Adeline Busson, Xavier Peyrassol, Françoise Wilkin, Bruno Pichon, Guillaume Smits, Isabelle Vandernoot, Jean‐Christophe Goffard, Michel Georges, Michel Moutschen, Benoît Misset, Gilles Darcis, Julien Guiot, Laurent Jadot, Samira Azarzar, Patricia Dellot, Stéphanie Gofflot, Sabine Claassen, Axelle Bertrand, Gilles Parzibut, Mathilde Clarinval, Catherine Moermans, Olivier Malaise, Kamilia El Kandoussi, Raphaël Thonon, Pascale Huynen, Alyssia Mesdagh, Sofia Ferreira Melo, Nicolas Jacques, Emmanuel Di Valentin, François Giroule,
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-19
Nature Portfolio
María J. Redondo, Susan Geyer, Andrea K. Steck, Seth A. Sharp, John M. Wentworth, Michael N. Weedon, Peter A. Antinozzi, Jay M. Sosenko, Mark A. Atkinson, Alberto Pugliese, Richard A. Oram, Peter A. Antinozzi, Mark A. Atkinson, Manuela Battaglia, Dorothy J. Becker, P. J. Bingley, Emanuele Bosi, Jan C. Buckner, Peter G. Colman, Peter A. Gottlieb, Kevan C. Herold, Richard A. Insel, Tom Kay, Mikael Knip, Jennifer B. Marks, Antoinette Moran, James L. Palmer, Mark Peakman, Louis H. Philipson, Alberto Pugliese, P. Raskin, Henry Rodriguez, Bart O. Roep, William E. Russell, Desmond Schatz, Diane K. Wherrett, Darrell M. Wilson, William E. Winter, Anette‐Gabriele Ziegler, Christophe Benoist, J.J. Blum, Peter Chase, Michael Clare‐Salzler, Raphael Clynes, George S. Eisenbarth, C. Garrison Fathman, Gilman D. Grave, Bernhard J. Hering, Francine Kaufman, Ellen W. Leschek, J. Mahon, Kirsti Näntö‐Salonen, Gerald T. Nepom, Tihamer Orban, Robertson Parkman, Mark D. Pescovitz, John Peyman, Maria Grazia Roncarolo, Olli Simell, Robert Sherwin, Mark Siegelman, Andrea K. Steck, James W. Thomas, Massimo Trucco, J. Richard Wagner, Carla J. Greenbaum, Katarzyna Bourcier, Richard A. Insel, Jeffrey P. Krischer, Ellen W. Leschek, Lisa Rafkin, Lisa M. Spain, Catherine C. Cowie, Mary A. Foulkes, Heidi Krause‐Steinrauf, John M. Lachin, Saúl Malozowski, John Peyman, J P Ridge, Peter J. Savage, Jay S. Skyler, Stephanie J. Zafonte, Norma S. Kenyon, Irene Santiago, Jay M. Sosenko, Brian N. Bundy, Michael Abbondondolo, Timothy E. Adams, Darlene Amado, Ilma Asif, Matthew Boonstra, Brian N. Bundy, Cristina Burroughs, David Cuthbertson, Mary Deemer, Christopher Eberhard, Steve Fiske, Julie Ford, Jennifer Garmeson, Heather Guillette, Susan Geyer, Brian Hays, Courtney Henderson, Martha Henry, Kathleen Heyman, Belinda Hsiao, Christina Karges, Nichole Keaton, Amanda Kinderman, Pat Law, Ashely Leinbach, Cristin Linton, Shu Liu, Jennifer Lloyd, Jamie Malloy, Kristin Maddox, Julie Martin, Jessica Miller, Éric Milliot, Margaret Moore, Sarah Müller, Thuy Trang Nguyen, Ryan O’Donnell, Vanessa Oduah, Jennifer Pilger, A. Roberts, Kelly Sadler, Tina Stavros, Roy Tamura, Keith Wood, Ping Xu, Kenneth C. Young, Persida Alies, Franz Badias, Aaron Baker, Monica Bassi, Craig A. Beam, David Boulware, London Bounmananh, Susan Bream, Doug Freeman, Jessica Gough, Jinin Ginem, Moriah Granger, M C Holloway, Michelle Kieffer, Page Lane, Lavanya Nallamshetty, Yazandra Parrimon, Kate Paulus, Joy Ramiro, AQesha Luvon Ritzie, Archana Sharma, Audrey Shor, Xiaohong Song, Amanda Terry, Jeanne Weinberger, Margaret Wootten, Pamela Harding, Susan McDonough, Paula McGee, Kimberly Owens Hess, Donna Phoebus, Scott Quinlan, Erica Raiden, Emily Batts, Chris Buddy, Kristin Kirpatrick, Mary Ramey, Ann Shultz, Chris Webb, Melita Romesco, Judith Fradkin, Emily A. Blumberg, Gerald J. Beck, David J. Brillon, Rose Gubitosi‐Klug, Lori M. Laffel, Robert M. Veatch, Dennis Wallace, Jonathan Braun, Åke Lernmark, Bernard C. Lo, Herman Mitchell, Ali Naji, Jørn Nerup, Trevor J. Orchard, Michael W. Steffes, Anastasios A. Tsiatis, Bernard Zinman, Brett Loechelt, Lindsey R. Baden, Michael D. Green, Adriana Weinberg, Santica M. Marcovina, Jerry P. Palmer, Adriana Weinberg, Liping Yu, Sunanda Babu, William E. Winter, George S. Eisenbarth, Polly J. Bingley, Raphael Clynes, Linda A. DiMeglio, George S. Eisenbarth, Brian Hays, Jennifer B. Marks, Della Matheson, Henry Rodriguez, Darrell M. Wilson, María J. Redondo, David Rodríguez‐Gómez, Xiati Zheng, Sandra Lidia Peralta Peña, Massimo Pietropaolo, Emily Batts, Tyler Brown, Jane H. Buckner, Angela Dove, Marissa Hammond, Deborah Hefty, Jani Klein, Kristen Kuhns, McKenzie Letlau, Sandra Lord, Marli McCulloch‐Olson, Lisa M. Miller, Gerald T. Nepom, Jared Odegard, Mary Ramey, Elaine Sachter, Marissa St. Marie, Kimberly Stickney, Dana VanBuecken, Ben Vellek, Christine A. Webber, Laurie Allen, Jenna Bollyk, Nicole Hilderman, Hebatullah Ismail, Steve Lamola, Srinath Sanda, Heather Vendettuoli, David Tridgell, Roshanak Monzavi, Meredith Bock, Lynda K. Fisher, Mary Halvorson, Debra Jeandron, Mimi S. Kim, Jamie Wood, Mitchell E. Geffner, Francine Kaufman, Robertson Parkman, Christine Salazar, Robin Goland, Raphael Clynes, Steve Cook, Matthew Freeby, Mary Gallagher, Rachelle Gandica, Ellen Greenberg, Amy Kurland, Sarah Pollak, Amy Wolk, Mary Chan, Linda Koplimae, Elizabeth Levine, Kelly Smith, Jeniece Trast, Linda A. DiMeglio, Janice Blum, Carmella Evans‐Molina, Robin Hufferd, Bonnie Jagielo, Christy Kruse, Vanessa Patrick, Mark Rigby, Maria Spall, Kim Swinney, Jennifer Terrell, Lyla Christner, LeeAnn Ford, Sheryl Lynch, M D Stamm Menendez, Patricia Merrill, Mark D. Pescovitz, Henry Rodriguez, Cielo Alleyn, David A. Baidal, S.D. Fay, Jason L. Gaglia, Brittany Resnick, Sarah Szubowicz, Gordon C. Weir, Ronald Benjamin,
OBJECTIVE We tested the ability of a type 1 diabetes (T1D) genetic risk score (GRS) to predict progression of islet autoimmunity and T1D in at-risk individuals. RESEARCH DESIGN AND METHODS We studied the 1,244 TrialNet Pathway to Prevention study participants (T1D patients’ relatives without diabetes and with one or more positive autoantibodies) who were genotyped with Illumina ImmunoChip (median [range] age at initial autoantibody determination 11.1 years [1.2–51.8], 48% male, 80.5% non-Hispanic white, ...
American Diabetes Association