Taku Ogura, Yasuo Mikami, Hitoshi Hase, Masaki Mori, Taturo Hayashida, Toshikazu Kubo,
... Dintinger H, Blum A, Olivier P, Laborde F, Bettembourg-Brault I, Pourel J, Loeuille D and Chary- ... Dintinger H, Blum A, Olivier P, Laborde F, Bettembourg-Brault I, Pourel J, Loeuille D and Chary- ...
Tópico(s): Spondyloarthritis Studies and Treatments
2005 - Slack Incorporated (United States) | Orthopedics
Michel Henrotay, Dalia Marques, Jean‐Claude Paicheler, Jean‐Claude Gall, André Nel,
A reconstruction of the palaeoenvironment of the insects Konservat-Lagerstatten from the lower Toarcian of Bascharage (Luxembourg) is proposed after the analysis of the stratigraphy and the fauna. It corresponds to an emersion episode during the process of filling of a bay.
Tópico(s): Paleontology and Stratigraphy of Fossils
1998 - Muséum national d'histoire naturelle | Geodiversitas
Tommaso Bosi, Federico Bigi, Andrea D’Ariano, Francesco Viti, Juan Pineda-Jaramillo,
... real train timetables for freight trains in the Bettembourg Eurohub Sud Terminal (Luxembourg) are used, and various ...
Tópico(s): Maritime Ports and Logistics
2023 - Elsevier BV | Computers & Industrial Engineering
Juan Pineda-Jaramillo, Federico Bigi, Tommaso Bosi, Francesco Viti, Andrea D’Ariano,
... Company of Luxembourg of freight rail operations between Bettembourg (Luxembourg) and other nine terminal stations across the ...
Tópico(s): Traffic Prediction and Management Techniques
2023 - Institute of Electrical and Electronics Engineers | IEEE Access
Giulio Superti‐Furga, Daniel H. Lackner, Tabea Wiedmer, Álvaro Inglés‐Prieto, Bárbara M. G. Barbosa, Enrico Girardi, Ulrich Goldmann, Bettina Gürtl, Kristaps Klavins, Christoph Klimek, Sabrina Lindinger, Eva Liñeiro-Retes, André C. Müller, Svenja Onstein, Gregor Redinger, Daniela Reil, Vitaly Sedlyarov, Gernot Wolf, Matthew Crawford, Robert A. Everley, David Hepworth, Shenping Liu, Stephen Noell, Mary Piotrowski, Robert V. Stanton, Hui Zhang, Salvatore Corallino, Andrea Faedo, Maria Insidioso, Giovanna Maresca, Loredana Redaelli, Francesca Sassone, Lia Scarabottolo, Michela Stucchi, Paola Tarroni, Sara Tremolada, Helena Batoulis, Andreas Becker, Eckhard Bender, Yung-Ning Chang, Alexander Ehrmann, Anke Müller‐Fahrnow, Vera Pütter, Diana Zindel, Bradford S. Hamilton, Martin Lenter, Diana Santacruz, Coralie Viollet, Charles E. Whitehurst, Kai Johnsson, Philipp Leippe, Birgit Baumgarten, Lena Chang, Yvonne Ibig, Martin Pfeifer, Jürgen Reinhardt, Julian Schönbett, Paul M. Selzer, Klaus Seuwen, Charles Bettembourg, Bruno Biton, Jörg Czech, Hélène de Foucauld, Michel Didier, Thomas Licher, Vincent Mikol, Antje Pommereau, Frédéric Puech, Veeranagouda Yaligara, A.M. Edwards, Brandon J. Bongers, Laura H. Heitman, Adriaan P. IJzerman, Hubert J. Sijben, Gerard J. P. van Westen, Justine M. Grixti, Douglas B. Kell, Farah Mughal, Neil Swainston, Marina Wright Muelas, Tina Bohstedt, N. Burgess-Brown, Liz Carpenter, Katharina L. Dürr, Jesper S. Hansen, Andreea Scacioc, Giulia Banci, Claire Colas, Daniela Digles, Gerhard F. Ecker, Barbara Füzi, Viktoria Gamsjäger, Melanie Grandits, Riccardo Martini, Florentina Troger, Patrick Altermatt, Cédric Doucerain, Franz Dürrenberger, Vania Manolova, Anna‐Lena Steck, Hanna Sundström, Maria Wilhelm, Claire M. Steppan,
The Innovative Medicines Initiative Consortium RESOLUTE has started to develop tools and produce data sets to de-orphanize transporters in the solute carrier protein (SLC) superfamily, thereby lowering the barrier for the scientific community to explore SLCs as an attractive drug target class. The Innovative Medicines Initiative Consortium RESOLUTE has started to develop tools and produce data sets to de-orphanize transporters in the solute carrier protein (SLC) superfamily, thereby lowering the barrier ...
Tópico(s): Amino Acid Enzymes and Metabolism
2020 - Nature Portfolio | Nature Reviews Drug Discovery
Fei Gao, Kevin Robe, Mathilde Bettembourg, Nathalia Navarro, Valérie Rofidal, Véronique Santoni, Frédéric Gaymard, Florence Vignols, Hannetz Roschzttardtz, Esther Izquierdo, Christian Dubos,
Iron (Fe) is an essential micronutrient for plant growth and development. Any defects in the maintenance of Fe homeostasis will alter plant productivity and the quality of their derived products. In Arabidopsis (Arabidopsis thaliana), the transcription factor ILR3 plays a central role in controlling Fe homeostasis. In this study, we identified bHLH121 as an ILR3-interacting transcription factor. Interaction studies showed that bHLH121 also interacts with the three closest homologs of ILR3 (i.e., basic- ...
Tópico(s): Plant nutrient uptake and metabolism
2019 - Oxford University Press | The Plant Cell
Julien Frouin, Antoine Languillaume, Justine Mas, Delphine Mieulet, Arnaud Boisnard, Axel Labeyrie, Mathilde Bettembourg, Charlotte Bureau, Eve Lorenzini, M. Portefaix, Patricia Turquay, Aurore Vernet, Christophe Périn, Nourollah Ahmadi, Brigitte Courtois,
Salinity tolerance is an important quality for European rice grown in river deltas. We evaluated the salinity tolerance of a panel of 235 temperate japonica rice accessions genotyped with 30,000 SNP markers. The panel was exposed to mild salt stress (50 mM NaCl; conductivity of 6 dS m-1) at the seedling stage. Eight different root and shoot growth parameters were measured for both the control and stressed treatments. The Na+ and K+ mass fractions of the stressed plants were measured using atomic ...
Tópico(s): Rice Cultivation and Yield Improvement
2018 - Public Library of Science | PLoS ONE
Jean François Dufayard, Mathilde Bettembourg, Iris Fischer, Gaëtan Droc, Emmanuel Guiderdoni, Christophe Périn, Nathalie Chantret, Anne Diévart,
Leucine-Rich Repeats Receptor-Like Kinase (LRR-RLK) genes represent a large and complex gene family in plants, mainly involved in development and stress responses. These receptors are composed of an LRR-containing extracellular domain (ECD), a transmembrane domain (TM) and an intracellular kinase domain (KD). To provide new perspectives on functional analyses of these genes in model and non-model plant species, we performed a phylogenetic analysis on 8,360 LRR-RLK receptors in 31 angiosperm genomes ( ...
Tópico(s): Plant Gene Expression Analysis
2017 - Frontiers Media | Frontiers in Plant Science
Mathilde Bettembourg, Audrey Dardou, Alain Audebert, Emilie Thomas, Julien Frouin, Emmanuel Guiderdoni, Nourollah Ahmadi, Christophe Périn, Anne Diévart, Brigitte Courtois,
Plant root systems play a major role in anchoring and in water and nutrient uptake from the soil. The root cone angle is an important parameter of the root system architecture because, combined with root depth, it helps to determine the volume of soil explored by the plant. Two genes, DRO1 and SOR1, and several QTLs for root cone angle have been discovered in the last 5 years.To find other QTLs linked to root cone angle, a genome-wide association mapping study was conducted on two panels of 162 ...
Tópico(s): Plant Molecular Biology Research
2017 - Springer Science+Business Media | Rice
Sophia Henry, Fanchon Divol, Mathilde Bettembourg, Charlotte Bureau, Emmanuel Guiderdoni, Christophe Périn, Anne Diévart,
The formation and differentiation of aerenchyma, i.e., air-containing cavities that are critical for flooding tolerance, take place exclusively in the cortex. The understanding of development and differentiation of the cortex is thus an important issue; however, studies on this tissue are limited, partly because of the lack of available molecular tools. We screened a commercially available library of cell wall antibodies to identify markers of cortical tissue in rice roots. Out of the 174 antibodies ...
Tópico(s): Plant Molecular Biology Research
2016 - Frontiers Media | Frontiers in Plant Science
Marc Lartaud, Christophe Périn, Brigitte Courtois, Emilie Thomas, Sophia Henry, Mathilde Bettembourg, Fanchon Divol, Nadège Lanau, Florence Artus, Charlotte Bureau, Jean‐Luc Verdeil, Gautier Sarah, Emmanuel Guiderdoni, Anne Diévart,
We developed the PHIV-RootCell software to quantify anatomical traits of rice roots transverse section images. Combined with an efficient root sample processing method for image acquisition, this program permits supervised measurements of areas (those of whole root section, stele, cortex and central metaxylem vessels), number of cell layers and number of cells per cell layer. The PHIV-RootCell toolset runs under ImageJ, an independent operating system that has a license-free status. To demonstrate ...
Tópico(s): Rice Cultivation and Yield Improvement
2015 - Frontiers Media | Frontiers in Plant Science
Anne Diévart, Christophe Périn, Judith Hirsch, Mathilde Bettembourg, Nadège Lanau, Florence Artus, Charlotte Bureau, Noël Nicolas, Gaëtan Droc, Peyramard Matthieu, Serge Pereira, Brigitte Courtois, Jean‐Benoit Morel, Emmanuel Guiderdoni,
Plants are constantly exposed to a variety of biotic and abiotic stresses that reduce their fitness and performance. At the molecular level, the perception of extracellular stimuli and the subsequent activation of defense responses require a complex interplay of signaling cascades, in which protein phosphorylation plays a central role. Several studies have shown that some members of the Leucine-Rich Repeat Receptor-Like Kinase (LRR-RLK) family are involved in stress and developmental pathways. We ...
Tópico(s): Plant nutrient uptake and metabolism
2015 - Elsevier BV | Plant Science
Marion Ouedraogo, Charles Bettembourg, Anthony Bretaudeau, Olivier Sallou, Christian Diot, Olivier Demeure, Frédéric Lecerf,
Background There has been a surge in studies linking genome structure and gene expression, with special focus on duplicated genes. Although initially duplicated from the same sequence, duplicated genes can diverge strongly over evolution and take on different functions or regulated expression. However, information on the function and expression of duplicated genes remains sparse. Identifying groups of duplicated genes in different genomes and characterizing their expression and function would therefore ...
Tópico(s): Gene expression and cancer classification
2012 - Public Library of Science | PLoS ONE
Marc Trossaërt, Pierre Boisseau, Agnès Quéméner, Marianne Sigaud, Marc Fouassier, Catherine Ternisien, A. LEFRANÇOIS‐BETTEMBOURG, Christine Tesson, Cathi-Ann Thomas, Stéphane Bézieau,
In most laboratories, the severity of hemophilia A is assessed by the factor VIII activity (FVIII:C) one-stage assay. However, comparisons of these results with those of two-stage assays can reveal discrepancies and suggest misdiagnosis.In this monocentric study, we measured FVIII:C with two methods (one-stage chronometric and chromogenic assays) in 307 (173 families) patients with moderate/mild hemophilia A. To compare results, we used a chronometric/chromogenic ratio. Discrepancy was defined as a ...
Tópico(s): Platelet Disorders and Treatments
2010 - Elsevier BV | Journal of Thrombosis and Haemostasis
J F Le Rouic, F Behar-Cohen, F. Azan, S. Bertin, O. Bettembourg, F Rumen, C Caudron, G Renard, D Chauvaud,
PURPOSE: Retinal detachment (RD) is a major complication of cataract surgery, which can be treated by either primary vitrectomy without indentation or the scleral buckling procedure. The aim of this study is to compare the results of these two techniques for the treatment of pseudophakic RD. PATIENTS AND METHODS: The charts of 40 patients (40 eyes) treated with scleral buckling for a primary pseudophakic RD were retrospectively studied and compared to the charts of 32 patients (32 eyes) treated with ...
Tópico(s): Vascular Malformations Diagnosis and Treatment
2008 - Elsevier BV | Journal Français d Ophtalmologie
Bénédicte Rennesson-Rey, Anne‐Christine Rat, Isabelle Chary-Valckenaere, Isabelle Bettembourg-Brault, Nadine Juge, Hervé Dintinger, J Pourel, Damien Lœuille,
To evaluate the influence of a joint effusion on the clinical response to a single injection of Hylan GF-20 for hip osteoarthritis. We prospectively included patients scheduled for intraarticular Hylan GF-20 injection to treat hip osteoarthritis. Disease severity was assessed based on the Kellgren-Lawrence radiological grade. Ultrasonography was performed to look for a joint effusion. The pain score on a visual analog scale, Lequesne algofunctional index, and WOMAC scores were recorded at baseline ...
Tópico(s): Veterinary Equine Medical Research
2008 - Elsevier BV | Joint Bone Spine
Keith Rawnsley, Martin de Keijzer, Lingli Wei, Solenn Bettembourg, W. Asyee, J.L. Massaferro, P. Swaby, Donna Drysdale, D. J. Boettcher,
Abstract Well performance is extremely variable in the stacked sequence of relatively tight Devonian and Mississippian carbonates in the northern part of the Waterton Complex, Alberta, Canada. This is despite having an extensively developed fracture system present in all the wells. In order to determine why some wells penetrated more permeable fractures than others, a full reinterpretation of the geophysical, structural, stress, matrix and dynamic data sets was carried out. Flow simulations at sector ...
Tópico(s): Hydraulic Fracturing and Reservoir Analysis
2007 - Geological Society of London | Geological Society London Special Publications
V. Hoenen-Clavert, Anne Christine Rat, Damien Loeuille, Isabelle Bettembourg-Brault, C. Michel-Batot, Alain Blum, J Pourel, Isabelle Chary-Valckenaere,
To determine the magnetic resonance imaging (MRI) criteria of most value in the assessment of patients with spondyloarthropathy (SpA) with axial or peripheral involvement.Fat suppressed (FS)-T2 and pre- and postinjection FS-T1 images were obtained in the most symptomatic region (axial or peripheral) of patients requiring tumor necrosis factor-a blockers. Thirty-eight MRI (21 axial and 17 peripheral) were blindly scored at synovial (S) and entheseal (E) sites by 2 experienced observers screening for 7 inflammatory ...
Tópico(s): Bone and Joint Diseases
2007 - The Journal of Rheumatology Publishing Company Limited | The Journal of Rheumatology
C. Michel-Batot, Hervé Dintinger, Alain Blum, Philippe Olivier, Fyriel Laborde, Isabelle Bettembourg-Brault, J Pourel, Damien Lœuille, Isabelle Chary-Valckenaere,
Only about 40 cases of septic arthritis of the facet joints have been reported to date. We report 6 new cases including 2 at the cervical spine, which is rarely involved. Mean age was 61.5 years; there were 5 men and 1 woman. Spinal pain and stiffness, fever, and asthenia were the presenting manifestations. Laboratory tests consistently showed inflammation. Among classical risk factors for infection, only noninsulin-dependent diabetes was noted, in a single patient. Mean time to the diagnosis was ...
Tópico(s): Osteomyelitis and Bone Disorders Research
2007 - Elsevier BV | Joint Bone Spine
Jérôme Canel, Jérôme Zaman, Julie Bettembourg, Marion Le Flem, S. Poissonnet,
Zirconium silicides are being investigated for use as neutron reflector materials for the next generation of nuclear power devices. Hot isostatically pressed monolithic Zr 3 Si 2 and reactive sintered Zr X Si Y composite are currently under development. The composite is obtained in situ and contains a ZrSi matrix embedding shell‐like Zr, Zr 2 Si, and ZrSi 2 domains with volume ratios depending on the initial Zr/Si ratio. Despite the lack of information on the mechanical properties of zirconium silicides, ...
Tópico(s): Advanced ceramic materials synthesis
2006 - Wiley | International Journal of Applied Ceramic Technology
Astrid Pinzano, Jean‐Pierre Ruaud, Yann Chéli, P. Gonord, Laurent Grossin, Isabelle Bettembourg-Brault, Pierre Gillet, E. Payan, Geneviève Guillot, P. Netter, Damien Lœuille,
Tópico(s): Knee injuries and reconstruction techniques
2004 - Springer Science+Business Media | Magnetic Resonance Materials in Physics Biology and Medicine
... Online publication date: 1-Jan-2012. Cochener B, Bettembourg O and Roussel B (2011) Sutures en ophtalmologie ...
Tópico(s): Pituitary Gland Disorders and Treatments
2004 - | Ophthalmic surgery, lasers & imaging retina
C. Jacobzone, C. Cochard-Marianowski, I. Kupfer, S. Benchekroun Bettembourg, Yves Dordain, L. Misery, Béatrice Cochener, B. Sassolas,
Background: Visual disturbance in the course of melanoma is rare.Specific localized metastases and drug toxic effects are frequently the cause.Recognition of a retinopathy raises several questions when the diagnosis of melanoma-associated retinopathy (MAR) can be confirmed.Descriptions of such patients in dermatologic literature are rare and deserve attention because therapeutic decisions are mandatory.Observations: A 70-year-old woman had a first melanoma in 1985 and a second primary melanoma in ...
Tópico(s): Ocular Oncology and Treatments
2004 - American Medical Association | Archives of Dermatology
Jean-François Le Rouic, O. Bettembourg, F D'Hermiès, F. Azan, G Renard, D Chauvaud,
Background To describe the indications for removal of Miragel episcleral buckles and to compare them with removed silicone sponges and solid silicone indentations. Methods Retrospective analysis of the charts of patients successfully treated for retinal detachment in whom the episcleral buckle was removed after surgery, with a minimal follow-up of 6 months. Results In a series of 90 eyes of 90 patients, including 38 cases of Miragel elements, 25 cases of solid silicone, and 27 cases of silicone ...
Tópico(s): Ocular Disorders and Treatments
2003 - Lippincott Williams & Wilkins | Retina
Christine Fardeau, Stéphane Romand, Narsing A. Rao, Nathalie Cassoux, O. Bettembourg, P. Thulliez, Phuc LeHoang,
PURPOSE: To determine the value of aqueous humor analysis for confirming the diagnosis of ocular toxoplasmosis in patients who present with atypical clinical features and to relate the results of local antibody production and polymerase chain reaction (PCR) with the extent of active retinitis and the immune status of the patient. DESIGN: Retrospective case series. METHODS: Sixty-seven consecutive patients with retinitis or retinochoroiditis that was clinically consistent with atypical ocular toxoplasmosis ...
Tópico(s): Herpesvirus Infections and Treatments
2002 - Elsevier BV | American Journal of Ophthalmology
Jean-François Le Rouic, Riad Antoine Bejjani, F. Azan, O. Bettembourg, G Renard, D Chauvaud,
Abstract. A step-by-step description of a surgical technique for episcleral Miragel® buckle removal is reported. After dissection of the conjunctiva and the capsule surrounding the Miragel® element, the extremity of the buckle is pulled out with a cryoprobe. The removal of Miragel® episcleral buckle with the cryoprobe is a safe and effective technique with a low fragmentation rate and a reduction of the surgical risk related to the use of sharp forceps near a possibly weakened sclera. Procedure ...
Tópico(s): Corneal surgery and disorders
2002 - | Ophthalmic surgery, lasers & imaging retina
P. Dureau, Tania Attié‐Bitach, Rémi Salomon, O. Bettembourg, Jeanne Amiel, Yves Uteza, Jean-Louis Dufier,
To characterize the ocular features of renal coloboma syndrome.Prospective, observational case series.Twelve patients referred by the pediatric nephrology clinic and the ophthalmic records of five additional patients.For each patient, age at the time of examination, gender, renal function, and presence of a mutation in the PAX2 gene were noted. All patients underwent measurement of visual acuity and anterior and posterior segment examination with fundus photography. Goldmann visual fields were tested ...
Tópico(s): Organ Donation and Transplantation
2001 - Elsevier BV | Ophthalmology
Jean-François Le Rouic, Riad Antoine Bejjani, F Rumen, C Caudron, O. Bettembourg, G Renard, D Chauvaud,
Tópico(s): Vascular Malformations Diagnosis and Treatment
2001 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology
A.M. Obry-Musset, D. Bettembourg, P.M. Cahen, I.C. Voegel, R.M. Frank,
With the introduction of fluoridated domestic salt in France in 1986, questions have arisen with respect to its efficacy in caries prevention. It has been of interest to compare the urinary excretion of fluoride in children who consume fluoridated salt to that in children who take fluoride tablets. Ninety-three schoolchildren, 10-14 years of age, participated in the study and were divided into four groups: group I consumed fluoridated salt with every meal; group II ate at a school restaurant once ...
Tópico(s): Dental Health and Care Utilization
1992 - Karger Publishers | Caries Research
Charles Bettembourg, Christian Diot, Olivier Dameron,
The analysis of gene annotations referencing back to Gene Ontology plays an important role in the interpretation of high-throughput experiments results. This analysis typically involves semantic similarity and particularity measures that quantify the importance of the Gene Ontology annotations. However, there is currently no sound method supporting the interpretation of the similarity and particularity values in order to determine whether two genes are similar or whether one gene has some significant ...
Tópico(s): Machine Learning in Bioinformatics
2015 - Public Library of Science | PLoS ONE