Ebrahim Yarali, Maria Klimopoulou, M. Kristen David, Pouyan E. Boukany, U. Staufer, Lidy E. Fratila‐Apachitei, Amir A. Zadpoor, Angelo Accardo, Mohammad J. Mirzaali,
... are two parameters determining the elastic behavior of biomaterials. While the effects of elastic modulus on the ... Poisson's ratio. The micro-architecture of meta-biomaterials determines not only the Poisson's ratio but ... micro-architectural parameters. Here, we computationally design meta-biomaterials with controlled Poisson's ratios, ranging between -0. ... size, and effective elastic modulus. The 3D meta-biomaterials were additively manufactured at the micro-scale using ... The response of murine preosteoblasts to these meta-biomaterials was then studied using in vitro cell culture ...
Tópico(s): Dental materials and restorations
2024 - Elsevier BV | Acta Biomaterialia
Xiang Meng, Wen-Da Wang, Su-Ran Li, Zhi‐Jun Sun, Lu Zhang,
... osteoarthritis, rheumatoid arthritis and osteoporosis. Conventional bone tissue biomaterials are not adequately adapted to complex bone microenvironment. ... IV) oxide, a variety of tailored cerium-based biomaterials have been widely developed, including bioactive glasses, scaffolds, ... we highlight the latest advances in cerium-based biomaterials for inflammatory and metabolic bone diseases and bone-related tumors. Tailored cerium-based biomaterials have already demonstrated their value in disease prevention, ...
Tópico(s): Nanoplatforms for cancer theranostics
2024 - Elsevier BV | Acta Biomaterialia
Mojtaba Ansari, Ahmad Darvishi,
... a wound to prevent infection and secondary damage. Biomaterials applied in wound management have advanced significantly. Natural biomaterials are increasingly used due to their advantages including ... expensive extraction methods. Therefore, their combination with synthetic biomaterials and/or adding bioactive agents has become an ... of natural wound healing and the effect of biomaterials on its direction, type, and level will be ... polysaccharides and proteins were selected as desirable natural biomaterials, polymers as synthetic biomaterials with variable and suitable ...
Tópico(s): Silk-based
2024 - Frontiers Media | Frontiers in Bioengineering and Biotechnology
Yan Wu, Luxin Li, Zuojun Ning, Changrong Li, Yongkui Yin, Kaiyuan Chen, Li Lu, Fei Xu, Jie Gao,
... stress and promoting cell differentiation. The interaction between biomaterials and tissue cells significantly affects biomaterial-tissue integration and tissue regeneration. In recent years, it has been found that biomaterials can affect various processes related to tissue regeneration by regulating autophagy. The utilization of biomaterials in a controlled environment has become a prominent ... migration, apoptosis, and extracellular matrix formation. In addition, biomaterials possess the potential to serve as carriers for ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2024 - BioMed Central | Cell Communication and Signaling
Xinran Song, Luodan Yu, Liang Chen, Yu Chen,
ConspectusCatalytic biomaterials, an emerging frontier in biomaterials research, offer tremendous potential to circumvent the limitations of traditional treatment approaches, such as low specificity and adverse effects. By harnessing the intrinsic physicochemical properties of materials, catalytic biomaterials, especially nanoscale catalytic biomaterials (termed catalytic nanomedicine), can directly engage with a ... The extensively investigated natural enzymes mimicked by catalytic biomaterials include peroxidases, oxidases, superoxide dismutases, catalase, and glutathione ...
Tópico(s): Extracellular vesicles in disease
2024 - American Chemical Society | Accounts of Materials Research
Hillary Mndlovu, Pradeep Kumar, Lisa C. du Toit, Yahya E. Choonara,
Abstract The biological response to biomaterials plays a crucial role in selecting suitable materials for the formulation and development of tissue engineering platforms. Biodegradation is one of the properties that is considered in selecting appropriate biomaterials for biomedical applications. Biodegradation is the process of ... distribution, metabolism, excretion, and toxicity (ADMET) process of biomaterials and small molecules in the body. Degradation of biomaterials can be followed by assessing the physical, mechanical, ...
Tópico(s): 3D Printing in Biomedical Research
2024 - Nature Portfolio | npj Materials Degradation
IntechOpen
Yomna K. Abdallah, Alberto T. Estévez,
... high-potential tool has opened wide possibilities for biomaterials research-driven design. That is based on developing biomaterials for multi-scale applications in the design realm ... reflect very detailed physical characteristics of the proposed biomaterials from micro to macro. However, this biomaterials research-driven design approach aided by AI text- ... generation models in this design process. Furthermore, since biomaterials research-driven design is focused not only on design studies but also the biomaterials engineering research and process, it requires a sufficient ...
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2023 - Multidisciplinary Digital Publishing Institute | Designs
Pralhad Pesode, Shivprakash Barve, Sagar V. Wankhede, Akbar Ahmad,
Over the past few years, 3D-printed biomaterials have gained widespread usage in the manufacturing of orthopaedic implants. 3D-printed implants have low weight, minimal material waste, ease of creation, the ... starch combinations have immense potential for generating sustainable biomaterials. Carbon, which is a key category of sustainable biomaterials, is found in a wide range of carbonaceous gels and biomaterials based on cellulose fibres and carbon nanotube. The ... the most recent developments, uses, and challenges for biomaterials made from sustainable resources. In this article, the ...
Tópico(s): 3D Printing in Biomedical Research
2023 - Hindawi Publishing Corporation | Advances in Materials Science and Engineering
Reeya Agrawal, Sangeeta Singh, Kuldeep K. Saxena, Dharam Buddhi,
The paper provides an introduction to biomaterials covered and their available types, such as metal, ceramic, polymer, and composites. Biomaterials are structures, devices, or materials that may repair or implant tissue. Biomaterials are biocompatible that have high mechanical strength, and need a long time to break down. A biomaterial is any natural or synthetic material that regularly ... and polymeric implant materials and systems. Polymers as biomaterials have had a significant impact on medical technology ...
Tópico(s): Bone Tissue Engineering Materials
2023 - SAGE Publishing | Proceedings of the Institution of Mechanical Engineers Part E Journal of Process Mechanical Engineering
Pratik Das, Suvendu Manna, Shivam Roy, Samit Kumar Nandi, Piyali Basak,
Abstract Background Biomaterials are vital products used in clinical sectors as alternatives to several biological macromolecules for tissue engineering techniques owing ... of wound healing relies on the type of biomaterials being incorporated for the fabrication of skin substitutes ... several databases to identify the most frequently used biomaterials for the development of successful wound healing agents ... advances in the utilization of natural and synthetic biomaterials (alone/in combination) to speed up the regeneration ...
Tópico(s): Periodontal Regeneration and Treatments
2023 - BioMed Central | Burns & Trauma
Minna Xiao, Qinglai Tang, Shiying Zeng, Qian Yang, Xinming Yang, Xinying Tong, Gangcai Zhu, Lanjie Lei, Shisheng Li,
... effects still limit its widespread application. Fortunately, advanced biomaterials effectively contribute immunotherapy and play an important role ... review discusses immunotherapies and the development of related biomaterials for application in the field. The review first ... mechanisms. Further, it focuses on the types of biomaterials applied in immunotherapy and related research on metal ... introduce the preparation and processing technologies of these biomaterials (liposomes, microspheres, microneedles, and hydrogels) and summarize their ...
Tópico(s): RNA Interference and Gene Delivery
2023 - BioMed Central | Biomaterials Research
Shutao Zhang, Hongtao Yang, Minqi Wang, Diego Mantovani, Ke Yang, Frank Witte, Lili Tan, Bing Yue, Xinhua Qu,
... combatting bacterial infections.•The design principles for antimicrobial biomaterials vary depending on the immune microenvironment at different stages of infection.•Immunomodulatory biomaterials display robust antimicrobial efficacy and vaccine attributes in ... immune microenvironment at different stages of infection makes biomaterials with direct antimicrobial activity unsatisfactory for the long- ... increasing mortality may be partly attributed to the biomaterials failing to modulate the active antimicrobial action of ...
Tópico(s): Immunotherapy and Immune Responses
2023 - Elsevier BV | The Innovation
Directory of Open Access Journals (DOAJ)
Md. Zobair Al Mahmud, Md Hosne Mobarak, Nayem Hossain, Md Aminul Islam, Md. Thohid Rayhan,
... driven by the development and utilization of innovative biomaterials. This comprehensive review aims to provide an in-depth analysis of emerging breakthroughs in biomaterials for orthopedic applications, focusing on the diverse range of materials employed in this sector. Biomaterials have revolutionized orthopedic surgery by offering tailored solutions ... improving overall quality of life. This review categorizes biomaterials into three main groups: metals, ceramics, and polymers, with a special emphasis on composite biomaterials. Metal alloys, such as titanium and its alloys, ...
Tópico(s): Titanium Alloys Microstructure and Properties
2023 - Elsevier BV | Bioprinting
Patritsia Stathatou, Liz Corbin, J. Carson Meredith, Alysia Garmulewicz,
Biomaterials, used here to signify 100% biobased and biodegradable materials, can offer a promising solution for transitioning ... combating plastic pollution. To ensure their environmental benefits, biomaterials must derive from regenerative, non-polluting feedstocks that ... by-products present a favorable feedstock option for biomaterials production. Although this is an improvement over sourcing ... must be considered. Furthermore, the nutrient value of biomaterials for specific soil ecosystems is often overlooked despite ...
Tópico(s): Microplastics and Plastic Pollution
2023 - Multidisciplinary Digital Publishing Institute | Sustainability
Pralhad Pesode, Shivprakash Barve,
... is beneficial for the research and development of biomaterials and the production of new sustainable biomaterials. Eco-friendly biomaterials should be promoted. As prospective substitutes for conventional materials, a variety of biomaterials have been conceived and produced to date and ... The sustainability component in the additive manufacturing of biomaterials is the main goal of this article. There is discussion of various metallic biomaterials, including titanium, stainless steel, magnesium, cobalt-chromium alloy, ...
Tópico(s): Bone Tissue Engineering Materials
2023 - Taylor & Francis | Journal of Industrial and Production Engineering